-
2
-
-
78049393407
-
Mitochondrial protein quality control systems in aging and disease
-
Luce K., Weil A.C., Osiewacz H.D. Mitochondrial protein quality control systems in aging and disease. Adv. Exp. Med. Biol. 2010, 694:108-125.
-
(2010)
Adv. Exp. Med. Biol.
, vol.694
, pp. 108-125
-
-
Luce, K.1
Weil, A.C.2
Osiewacz, H.D.3
-
4
-
-
46349103594
-
A mitochondrial protein compendium elucidates complex I disease biology
-
Pagliarini D.J., Calvo S.E., Chang B., Sheth S.A., Vafai S.B., Ong S.E., Walford G.A., Sugiana C., Boneh A., Chen W.K., Hill D.E., Vidal M., Evans J.G., Thorburn D.R., Carr S.A., Mootha V.K. A mitochondrial protein compendium elucidates complex I disease biology. Cell 2008, 134:112-123.
-
(2008)
Cell
, vol.134
, pp. 112-123
-
-
Pagliarini, D.J.1
Calvo, S.E.2
Chang, B.3
Sheth, S.A.4
Vafai, S.B.5
Ong, S.E.6
Walford, G.A.7
Sugiana, C.8
Boneh, A.9
Chen, W.K.10
Hill, D.E.11
Vidal, M.12
Evans, J.G.13
Thorburn, D.R.14
Carr, S.A.15
Mootha, V.K.16
-
5
-
-
68749112707
-
Importing mitochondrial proteins: machineries and mechanisms
-
Chacinska A., Koehler C.M., Milenkovic D., Lithgow T., Pfanner N. Importing mitochondrial proteins: machineries and mechanisms. Cell 2009, 138:628-644.
-
(2009)
Cell
, vol.138
, pp. 628-644
-
-
Chacinska, A.1
Koehler, C.M.2
Milenkovic, D.3
Lithgow, T.4
Pfanner, N.5
-
6
-
-
71749108967
-
Mitochondrial protein homeostasis: the cooperative roles of chaperones and proteases
-
Voos W. Mitochondrial protein homeostasis: the cooperative roles of chaperones and proteases. Res. Microbiol. 2009, 160:718-725.
-
(2009)
Res. Microbiol.
, vol.160
, pp. 718-725
-
-
Voos, W.1
-
7
-
-
77956362155
-
Protein homeostasis and aging in neurodegeneration
-
Douglas P.M., Dillin A. Protein homeostasis and aging in neurodegeneration. J. Cell Biol. 2010, 190:719-729.
-
(2010)
J. Cell Biol.
, vol.190
, pp. 719-729
-
-
Douglas, P.M.1
Dillin, A.2
-
8
-
-
33646127577
-
Molecular chaperones and protein quality control
-
Bukau B., Weissman J., Horwich A. Molecular chaperones and protein quality control. Cell 2006, 125:443-451.
-
(2006)
Cell
, vol.125
, pp. 443-451
-
-
Bukau, B.1
Weissman, J.2
Horwich, A.3
-
9
-
-
78049383942
-
Protein homeostasis in models of aging and age-related conformational disease
-
Kikis E.A., Gidalevitz T., Morimoto R.I. Protein homeostasis in models of aging and age-related conformational disease. Adv. Exp. Med. Biol. 2010, 694:138-159.
-
(2010)
Adv. Exp. Med. Biol.
, vol.694
, pp. 138-159
-
-
Kikis, E.A.1
Gidalevitz, T.2
Morimoto, R.I.3
-
10
-
-
1542344435
-
Proteasomes and their kin: proteases in the machine age
-
Pickart C.M., Cohen R.E. Proteasomes and their kin: proteases in the machine age. Nat. Rev. Mol. Cell Biol. 2004, 5:177-187.
-
(2004)
Nat. Rev. Mol. Cell Biol.
, vol.5
, pp. 177-187
-
-
Pickart, C.M.1
Cohen, R.E.2
-
11
-
-
79959389010
-
AAA+ proteases: ATP-fueled machines of protein destruction
-
Sauer R.T., Baker T.A. AAA+ proteases: ATP-fueled machines of protein destruction. Annu. Rev. Biochem. 2011, 80:587-612.
-
(2011)
Annu. Rev. Biochem.
, vol.80
, pp. 587-612
-
-
Sauer, R.T.1
Baker, T.A.2
-
12
-
-
0037009130
-
Molecular chaperones as essential mediators of mitochondrial biogenesis
-
Voos W., Röttgers K. Molecular chaperones as essential mediators of mitochondrial biogenesis. Biochim. Biophys. Acta 2002, 1592:51-62.
-
(2002)
Biochim. Biophys. Acta
, vol.1592
, pp. 51-62
-
-
Voos, W.1
Röttgers, K.2
-
13
-
-
33745475570
-
On the brotherhood of the mitochondrial chaperones mortalin and heat shock protein 60
-
Deocaris C.C., Kaul S.C., Wadhwa R. On the brotherhood of the mitochondrial chaperones mortalin and heat shock protein 60. Cell Stress Chaperones 2006, 11:116-128.
-
(2006)
Cell Stress Chaperones
, vol.11
, pp. 116-128
-
-
Deocaris, C.C.1
Kaul, S.C.2
Wadhwa, R.3
-
14
-
-
17044387386
-
Hsp70 chaperones: cellular functions and molecular mechanism
-
Mayer M.P., Bukau B. Hsp70 chaperones: cellular functions and molecular mechanism. Cell. Mol. Life Sci. 2005, 62:670-684.
-
(2005)
Cell. Mol. Life Sci.
, vol.62
, pp. 670-684
-
-
Mayer, M.P.1
Bukau, B.2
-
15
-
-
0028965273
-
Partner proteins determine multiple functions of hsp70s
-
Rassow J., Voos W., Pfanner N. Partner proteins determine multiple functions of hsp70s. Trends Cell Biol. 1995, 5:207-212.
-
(1995)
Trends Cell Biol.
, vol.5
, pp. 207-212
-
-
Rassow, J.1
Voos, W.2
Pfanner, N.3
-
16
-
-
33646847503
-
The diverse roles of J-proteins, the obligate Hsp70 co-chaperone
-
Craig E.A., Huang P., Aron R., Andrew A. The diverse roles of J-proteins, the obligate Hsp70 co-chaperone. Rev. Physiol. Biochem. Pharmacol. 2006, 156:1-21.
-
(2006)
Rev. Physiol. Biochem. Pharmacol.
, vol.156
, pp. 1-21
-
-
Craig, E.A.1
Huang, P.2
Aron, R.3
Andrew, A.4
-
17
-
-
0031556950
-
Mge1 functions as a nucleotide release factor for Ssc1, a mitochondrial Hsp70 of Saccharomyces cerevisiae
-
Miao B., Davis J.E., Craig E.A. Mge1 functions as a nucleotide release factor for Ssc1, a mitochondrial Hsp70 of Saccharomyces cerevisiae. J. Mol. Biol. 1997, 265:541-552.
-
(1997)
J. Mol. Biol.
, vol.265
, pp. 541-552
-
-
Miao, B.1
Davis, J.E.2
Craig, E.A.3
-
18
-
-
77953021149
-
The ribosome-bound Hsp70 homolog Ssb of Saccharomyces cerevisiae
-
Peisker K., Chiabudini M., Rospert S. The ribosome-bound Hsp70 homolog Ssb of Saccharomyces cerevisiae. Biochim. Biophys. Acta 2010, 1803:662-672.
-
(2010)
Biochim. Biophys. Acta
, vol.1803
, pp. 662-672
-
-
Peisker, K.1
Chiabudini, M.2
Rospert, S.3
-
19
-
-
0023182502
-
SSC1, a member of the 70-kDa heat shock protein multigene family of Saccharomyces cerevisiae, is essential for growth
-
Craig E.A., Kramer J., Kosic-Smithers J. SSC1, a member of the 70-kDa heat shock protein multigene family of Saccharomyces cerevisiae, is essential for growth. Proc. Natl. Acad. Sci. U. S. A. 1987, 84:4156-4160.
-
(1987)
Proc. Natl. Acad. Sci. U. S. A.
, vol.84
, pp. 4156-4160
-
-
Craig, E.A.1
Kramer, J.2
Kosic-Smithers, J.3
-
20
-
-
0025039149
-
Requirement for hsp70 in the mitochondrial matrix for translocation and folding of precursor proteins
-
Kang P.J., Ostermann J., Shilling J., Neupert W., Craig E.A., Pfanner N. Requirement for hsp70 in the mitochondrial matrix for translocation and folding of precursor proteins. Nature 1990, 348:137-143.
-
(1990)
Nature
, vol.348
, pp. 137-143
-
-
Kang, P.J.1
Ostermann, J.2
Shilling, J.3
Neupert, W.4
Craig, E.A.5
Pfanner, N.6
-
21
-
-
0033782977
-
The mitochondrial protein import motor
-
Strub A., Lim J.H., Pfanner N., Voos W. The mitochondrial protein import motor. Biol. Chem. 2000, 381:943-949.
-
(2000)
Biol. Chem.
, vol.381
, pp. 943-949
-
-
Strub, A.1
Lim, J.H.2
Pfanner, N.3
Voos, W.4
-
22
-
-
0034328890
-
Protein unfolding by mitochondria. The Hsp70 import motor
-
Matouschek A., Pfanner N., Voos W. Protein unfolding by mitochondria. The Hsp70 import motor. EMBO Rep. 2000, 1:404-410.
-
(2000)
EMBO Rep.
, vol.1
, pp. 404-410
-
-
Matouschek, A.1
Pfanner, N.2
Voos, W.3
-
23
-
-
0027490849
-
A dual role for mitochondrial heat shock protein 70 in membrane translocation of preproteins
-
Gambill B.D., Voos W., Kang P.J., Miao B., Langer T., Craig E.A., Pfanner N. A dual role for mitochondrial heat shock protein 70 in membrane translocation of preproteins. J. Cell Biol. 1993, 123:109-117.
-
(1993)
J. Cell Biol.
, vol.123
, pp. 109-117
-
-
Gambill, B.D.1
Voos, W.2
Kang, P.J.3
Miao, B.4
Langer, T.5
Craig, E.A.6
Pfanner, N.7
-
24
-
-
0033612301
-
The protein import motor of mitochondria: unfolding and trapping of preproteins are distinct and separable functions of matrix Hsp70
-
Voisine C., Craig E.A., Zufall N., von Ahsen O., Pfanner N., Voos W. The protein import motor of mitochondria: unfolding and trapping of preproteins are distinct and separable functions of matrix Hsp70. Cell 1999, 97:565-574.
-
(1999)
Cell
, vol.97
, pp. 565-574
-
-
Voisine, C.1
Craig, E.A.2
Zufall, N.3
von Ahsen, O.4
Pfanner, N.5
Voos, W.6
-
25
-
-
0028046847
-
Mitochondrial protein import: biochemical and genetic evidence for interaction of matrix hsp70 and the inner membrane protein MIM44
-
Rassow J., Maarse A.C., Krainer E., Kübrich M., Müller H., Meijer M., Craig E.A., Pfanner N. Mitochondrial protein import: biochemical and genetic evidence for interaction of matrix hsp70 and the inner membrane protein MIM44. J. Cell Biol. 1994, 127:1547-1556.
-
(1994)
J. Cell Biol.
, vol.127
, pp. 1547-1556
-
-
Rassow, J.1
Maarse, A.C.2
Krainer, E.3
Kübrich, M.4
Müller, H.5
Meijer, M.6
Craig, E.A.7
Pfanner, N.8
-
26
-
-
0028556615
-
Dynamic interaction between Isp45 and mitochondrial hsp70 in the protein import system of the yeast mitochondrial inner membrane
-
Kronidou N.G., Oppliger W., Bolliger L., Hannavy K., Glick B.S., Schatz G., Horst M. Dynamic interaction between Isp45 and mitochondrial hsp70 in the protein import system of the yeast mitochondrial inner membrane. Proc. Natl. Acad. Sci. U. S. A. 1994, 91:12818-12822.
-
(1994)
Proc. Natl. Acad. Sci. U. S. A.
, vol.91
, pp. 12818-12822
-
-
Kronidou, N.G.1
Oppliger, W.2
Bolliger, L.3
Hannavy, K.4
Glick, B.S.5
Schatz, G.6
Horst, M.7
-
27
-
-
4444315535
-
The presequence translocase-associated protein import motor of mitochondria. Pam16 functions in an antagonistic manner to Pam18
-
Li Y., Dudek J., Guiard B., Pfanner N., Rehling P., Voos W. The presequence translocase-associated protein import motor of mitochondria. Pam16 functions in an antagonistic manner to Pam18. J. Biol. Chem. 2004, 279:38047-38054.
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 38047-38054
-
-
Li, Y.1
Dudek, J.2
Guiard, B.3
Pfanner, N.4
Rehling, P.5
Voos, W.6
-
28
-
-
0141865519
-
Tim14, a novel key component of the import motor of the TIM23 protein translocase of mitochondria
-
Mokranjac D., Sichting M., Neupert W., Hell K. Tim14, a novel key component of the import motor of the TIM23 protein translocase of mitochondria. EMBO J. 2003, 22:4945-4956.
-
(2003)
EMBO J.
, vol.22
, pp. 4945-4956
-
-
Mokranjac, D.1
Sichting, M.2
Neupert, W.3
Hell, K.4
-
29
-
-
10744228445
-
A J-protein is an essential subunit of the presequence translocase associated protein import motor of mitochondria
-
Truscott K.N., Voos W., Frazier A.E., Lind M., Li Y., Geissler A., Dudek J., Müller H., Sickmann A., Meyer H.E., Meisinger C., Guiard B., Rehling P., Pfanner N. A J-protein is an essential subunit of the presequence translocase associated protein import motor of mitochondria. J. Cell Biol. 2003, 163:707-713.
-
(2003)
J. Cell Biol.
, vol.163
, pp. 707-713
-
-
Truscott, K.N.1
Voos, W.2
Frazier, A.E.3
Lind, M.4
Li, Y.5
Geissler, A.6
Dudek, J.7
Müller, H.8
Sickmann, A.9
Meyer, H.E.10
Meisinger, C.11
Guiard, B.12
Rehling, P.13
Pfanner, N.14
-
30
-
-
0345133332
-
J-protein co-chaperone of the mitochondrial inner membrane required for protein import into the mitochondrial matrix
-
D'Silva P., Schilke B., Walter W., Andrew A., Craig E. J-protein co-chaperone of the mitochondrial inner membrane required for protein import into the mitochondrial matrix. Proc. Natl. Acad. Sci. U. S. A. 2003, 100:13839-13844.
-
(2003)
Proc. Natl. Acad. Sci. U. S. A.
, vol.100
, pp. 13839-13844
-
-
D'Silva, P.1
Schilke, B.2
Walter, W.3
Andrew, A.4
Craig, E.5
-
31
-
-
0027994692
-
Mitochondrial GrpE is present in a complex with hsp70 and preproteins in transit across membranes
-
Voos W., Gambill B.D., Laloraya S., Ang D., Craig E.A., Pfanner N. Mitochondrial GrpE is present in a complex with hsp70 and preproteins in transit across membranes. Mol. Cell. Biol. 1994, 14:6627-6634.
-
(1994)
Mol. Cell. Biol.
, vol.14
, pp. 6627-6634
-
-
Voos, W.1
Gambill, B.D.2
Laloraya, S.3
Ang, D.4
Craig, E.A.5
Pfanner, N.6
-
32
-
-
0029856628
-
The nucleotide exchange factor MGE exerts a key function in the ATP-dependent cycle of mt-Hsp70-Tim44 interaction driving mitochondrial protein import
-
Schneider H.C., Westermann B., Neupert W., Brunner M. The nucleotide exchange factor MGE exerts a key function in the ATP-dependent cycle of mt-Hsp70-Tim44 interaction driving mitochondrial protein import. EMBO J. 1996, 15:5796-5803.
-
(1996)
EMBO J.
, vol.15
, pp. 5796-5803
-
-
Schneider, H.C.1
Westermann, B.2
Neupert, W.3
Brunner, M.4
-
33
-
-
0029670827
-
The delta psi- and Hsp70/MIM44-dependent reaction cycle driving early steps of protein import into mitochondria
-
Ungermann C., Guiard B., Neupert W., Cyr D.M. The delta psi- and Hsp70/MIM44-dependent reaction cycle driving early steps of protein import into mitochondria. EMBO J. 1996, 15:735-744.
-
(1996)
EMBO J.
, vol.15
, pp. 735-744
-
-
Ungermann, C.1
Guiard, B.2
Neupert, W.3
Cyr, D.M.4
-
34
-
-
0029934520
-
Differential requirement for the mitochondrial Hsp70-Tim44 complex in unfolding and translocation of preproteins
-
Voos W., von Ahsen O., Müller H., Guiard B., Rassow J., Pfanner N. Differential requirement for the mitochondrial Hsp70-Tim44 complex in unfolding and translocation of preproteins. EMBO J. 1996, 15:2668-2677.
-
(1996)
EMBO J.
, vol.15
, pp. 2668-2677
-
-
Voos, W.1
von Ahsen, O.2
Müller, H.3
Guiard, B.4
Rassow, J.5
Pfanner, N.6
-
35
-
-
0037099608
-
The protein import motor of mitochondria: a targeted molecular ratchet driving unfolding and translocation
-
Okamoto K., Brinker A., Paschen S.A., Moarefi I., Hayer-Hartl M., Neupert W., Brunner M. The protein import motor of mitochondria: a targeted molecular ratchet driving unfolding and translocation. EMBO J. 2002, 21:3659-3671.
-
(2002)
EMBO J.
, vol.21
, pp. 3659-3671
-
-
Okamoto, K.1
Brinker, A.2
Paschen, S.A.3
Moarefi, I.4
Hayer-Hartl, M.5
Neupert, W.6
Brunner, M.7
-
36
-
-
0035282966
-
The mitochondrial Hsp70-dependent import system actively unfolds preproteins and shortens the lag phase of translocation
-
Lim J.H., Martin F., Guiard B., Pfanner N., Voos W. The mitochondrial Hsp70-dependent import system actively unfolds preproteins and shortens the lag phase of translocation. EMBO J. 2001, 20:941-950.
-
(2001)
EMBO J.
, vol.20
, pp. 941-950
-
-
Lim, J.H.1
Martin, F.2
Guiard, B.3
Pfanner, N.4
Voos, W.5
-
37
-
-
33646557371
-
Hsp70 chaperones accelerate protein translocation and the unfolding of stable protein aggregates by entropic pulling
-
De Los Rios P., Ben-Zvi A., Slutsky O., Azem A., Goloubinoff P. Hsp70 chaperones accelerate protein translocation and the unfolding of stable protein aggregates by entropic pulling. Proc. Natl. Acad. Sci. U. S. A. 2006, 103:6166-6171.
-
(2006)
Proc. Natl. Acad. Sci. U. S. A.
, vol.103
, pp. 6166-6171
-
-
De Los Rios, P.1
Ben-Zvi, A.2
Slutsky, O.3
Azem, A.4
Goloubinoff, P.5
-
38
-
-
0035794158
-
Mitochondrial Hsp70 Ssc1: role in protein folding
-
Liu Q., Krzewska J., Liberek K., Craig E.A. Mitochondrial Hsp70 Ssc1: role in protein folding. J. Biol. Chem. 2001, 276:6112-6118.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 6112-6118
-
-
Liu, Q.1
Krzewska, J.2
Liberek, K.3
Craig, E.A.4
-
39
-
-
0030933229
-
Sequential action of two hsp70 complexes during protein import into mitochondria
-
Horst M., Oppliger W., Rospert S., Schönfeld H.J., Schatz G., Azem A. Sequential action of two hsp70 complexes during protein import into mitochondria. EMBO J. 1997, 16:1842-1849.
-
(1997)
EMBO J.
, vol.16
, pp. 1842-1849
-
-
Horst, M.1
Oppliger, W.2
Rospert, S.3
Schönfeld, H.J.4
Schatz, G.5
Azem, A.6
-
40
-
-
0028284879
-
Mdj1p, a novel chaperone of the DnaJ family, is involved in mitochondrial biogenesis and protein folding
-
Rowley N., Prip-Buus C., Westermann B., Brown C., Schwarz E., Barrell B., Neupert W. Mdj1p, a novel chaperone of the DnaJ family, is involved in mitochondrial biogenesis and protein folding. Cell 1994, 77:249-259.
-
(1994)
Cell
, vol.77
, pp. 249-259
-
-
Rowley, N.1
Prip-Buus, C.2
Westermann, B.3
Brown, C.4
Schwarz, E.5
Barrell, B.6
Neupert, W.7
-
41
-
-
0029020451
-
The role of the GrpE homologue, Mge1p, in mediating protein import and protein folding in mitochondria
-
Westermann B., Prip-Buus C., Neupert W., Schwarz E. The role of the GrpE homologue, Mge1p, in mediating protein import and protein folding in mitochondria. EMBO J. 1995, 14:3452-3460.
-
(1995)
EMBO J.
, vol.14
, pp. 3452-3460
-
-
Westermann, B.1
Prip-Buus, C.2
Neupert, W.3
Schwarz, E.4
-
42
-
-
0033499799
-
Dual role of the mitochondrial chaperone Mdj1p in inheritance of mitochondrial DNA in yeast
-
Duchniewicz M., Germaniuk A., Westermann B., Neupert W., Schwarz E., Marszalek J. Dual role of the mitochondrial chaperone Mdj1p in inheritance of mitochondrial DNA in yeast. Mol. Cell. Biol. 1999, 19:8201-8210.
-
(1999)
Mol. Cell. Biol.
, vol.19
, pp. 8201-8210
-
-
Duchniewicz, M.1
Germaniuk, A.2
Westermann, B.3
Neupert, W.4
Schwarz, E.5
Marszalek, J.6
-
43
-
-
0028073776
-
Mitochondrial heat shock protein 70, a molecular chaperone for proteins encoded by mitochondrial DNA
-
Herrmann J.M., Stuart R.A., Craig E.A., Neupert W. Mitochondrial heat shock protein 70, a molecular chaperone for proteins encoded by mitochondrial DNA. J. Cell Biol. 1994, 127:893-902.
-
(1994)
J. Cell Biol.
, vol.127
, pp. 893-902
-
-
Herrmann, J.M.1
Stuart, R.A.2
Craig, E.A.3
Neupert, W.4
-
44
-
-
0029757416
-
The cold sensitivity of a mutant of Saccharomyces cerevisiae lacking a mitochondrial heat shock protein 70 is suppressed by loss of mitochondrial DNA
-
Schilke B., Forster J., Davis J., James P., Walter W., Laloraya S., Johnson J., Miao B., Craig E.A. The cold sensitivity of a mutant of Saccharomyces cerevisiae lacking a mitochondrial heat shock protein 70 is suppressed by loss of mitochondrial DNA. J. Cell Biol. 1996, 134:603-613.
-
(1996)
J. Cell Biol.
, vol.134
, pp. 603-613
-
-
Schilke, B.1
Forster, J.2
Davis, J.3
James, P.4
Walter, W.5
Laloraya, S.6
Johnson, J.7
Miao, B.8
Craig, E.A.9
-
45
-
-
0032540929
-
Mt-Hsp70 homolog, Ssc2p, required for maturation of yeast frataxin and mitochondrial iron homeostasis
-
Knight S.A.B., Sepuri N.B.V., Pain D., Dancis A. Mt-Hsp70 homolog, Ssc2p, required for maturation of yeast frataxin and mitochondrial iron homeostasis. J. Biol. Chem. 1998, 273:18389-18393.
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 18389-18393
-
-
Knight, S.A.B.1
Sepuri, N.B.V.2
Pain, D.3
Dancis, A.4
-
46
-
-
0033621156
-
Evidence for a conserved system for iron metabolism in the mitochondria of Saccharomyces cerevisiae
-
Schilke B., Voisine C., Beinert H., Craig E. Evidence for a conserved system for iron metabolism in the mitochondria of Saccharomyces cerevisiae. Proc. Natl. Acad. Sci. U. S. A. 1999, 96:10206-10211.
-
(1999)
Proc. Natl. Acad. Sci. U. S. A.
, vol.96
, pp. 10206-10211
-
-
Schilke, B.1
Voisine, C.2
Beinert, H.3
Craig, E.4
-
47
-
-
47249094614
-
Maturation of iron-sulfur proteins in eukaryotes: mechanisms, connected processes, and diseases
-
Lill R., Muhlenhoff U. Maturation of iron-sulfur proteins in eukaryotes: mechanisms, connected processes, and diseases. Annu. Rev. Biochem. 2008, 77:669-700.
-
(2008)
Annu. Rev. Biochem.
, vol.77
, pp. 669-700
-
-
Lill, R.1
Muhlenhoff, U.2
-
48
-
-
0035970292
-
The mitochondrial proteins Ssq1 and Jac1 are required for the assembly of iron sulfur clusters in mitochondria
-
Lutz T., Westermann B., Neupert W., Herrmann J.M. The mitochondrial proteins Ssq1 and Jac1 are required for the assembly of iron sulfur clusters in mitochondria. J. Mol. Biol. 2001, 307:815-825.
-
(2001)
J. Mol. Biol.
, vol.307
, pp. 815-825
-
-
Lutz, T.1
Westermann, B.2
Neupert, W.3
Herrmann, J.M.4
-
49
-
-
0035852737
-
Jac1, a mitochondrial J-type chaperone, is involved in the biogenesis of Fe/S clusters in Saccharomyces cerevisiae
-
Voisine C., Cheng Y.C., Ohlson M., Schilke B., Hoff K., Beinert H., Marszalek J., Craig E.A. Jac1, a mitochondrial J-type chaperone, is involved in the biogenesis of Fe/S clusters in Saccharomyces cerevisiae. Proc. Natl. Acad. Sci. U. S. A. 2001, 98:1483-1488.
-
(2001)
Proc. Natl. Acad. Sci. U. S. A.
, vol.98
, pp. 1483-1488
-
-
Voisine, C.1
Cheng, Y.C.2
Ohlson, M.3
Schilke, B.4
Hoff, K.5
Beinert, H.6
Marszalek, J.7
Craig, E.A.8
-
50
-
-
0035850757
-
The two mitochondrial heat shock proteins 70, Ssc1 and Ssq1, compete for the cochaperone Mge1
-
Schmidt S., Strub A., Röttgers K., Zufall N., Voos W. The two mitochondrial heat shock proteins 70, Ssc1 and Ssq1, compete for the cochaperone Mge1. J. Mol. Biol. 2001, 313:13-26.
-
(2001)
J. Mol. Biol.
, vol.313
, pp. 13-26
-
-
Schmidt, S.1
Strub, A.2
Röttgers, K.3
Zufall, N.4
Voos, W.5
-
51
-
-
3142716203
-
Sequence-specific interaction between mitochondrial Fe-S scaffold protein Isu and Hsp70 Ssq1 is essential for their in vivo function
-
Dutkiewicz R., Schilke B., Cheng S., Knieszner H., Craig E.A., Marszalek J. Sequence-specific interaction between mitochondrial Fe-S scaffold protein Isu and Hsp70 Ssq1 is essential for their in vivo function. J. Biol. Chem. 2004, 279:29167-29174.
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 29167-29174
-
-
Dutkiewicz, R.1
Schilke, B.2
Cheng, S.3
Knieszner, H.4
Craig, E.A.5
Marszalek, J.6
-
52
-
-
33744948235
-
Characterization of the interaction between the J-protein Jac1p and the scaffold for Fe-S cluster biogenesis, Isu1p
-
Andrew A.J., Dutkiewicz R., Knieszner H., Craig E.A., Marszalek J. Characterization of the interaction between the J-protein Jac1p and the scaffold for Fe-S cluster biogenesis, Isu1p. J. Biol. Chem. 2006, 281:14580-14587.
-
(2006)
J. Biol. Chem.
, vol.281
, pp. 14580-14587
-
-
Andrew, A.J.1
Dutkiewicz, R.2
Knieszner, H.3
Craig, E.A.4
Marszalek, J.5
-
53
-
-
33646342998
-
The Hsp70 chaperone Ssq1p is dispensable for iron-sulfur cluster formation on the scaffold protein Isu1p
-
Dutkiewicz R., Marszalek J., Schilke B., Craig E.A., Lill R., Mühlenhoff U. The Hsp70 chaperone Ssq1p is dispensable for iron-sulfur cluster formation on the scaffold protein Isu1p. J. Biol. Chem. 2006, 281:7801-7808.
-
(2006)
J. Biol. Chem.
, vol.281
, pp. 7801-7808
-
-
Dutkiewicz, R.1
Marszalek, J.2
Schilke, B.3
Craig, E.A.4
Lill, R.5
Mühlenhoff, U.6
-
54
-
-
0036809967
-
Structure and function of the GroE chaperone
-
Walter S. Structure and function of the GroE chaperone. Cell. Mol. Life Sci. 2002, 59:1589-1597.
-
(2002)
Cell. Mol. Life Sci.
, vol.59
, pp. 1589-1597
-
-
Walter, S.1
-
55
-
-
0024396544
-
Identification and electron microscopic analysis of a chaperonin oligomer from Neurospora crassa mitochondria
-
Hutchinson E.G., Tichelaar W., Hofhaus G., Weiss H., Leonard K.R. Identification and electron microscopic analysis of a chaperonin oligomer from Neurospora crassa mitochondria. EMBO J. 1989, 8:1485-1490.
-
(1989)
EMBO J.
, vol.8
, pp. 1485-1490
-
-
Hutchinson, E.G.1
Tichelaar, W.2
Hofhaus, G.3
Weiss, H.4
Leonard, K.R.5
-
56
-
-
0024972083
-
Mitochondrial heat-shock protein hsp60 is essential for assembly of proteins imported into yeast mitochondria
-
Cheng M.Y., Hartl F.U., Martin J., Pollock R.A., Kalusek F., Neupert W., Hallberg E.M., Hallberg R.L., Horwich A.L. Mitochondrial heat-shock protein hsp60 is essential for assembly of proteins imported into yeast mitochondria. Nature 1989, 337:620-625.
-
(1989)
Nature
, vol.337
, pp. 620-625
-
-
Cheng, M.Y.1
Hartl, F.U.2
Martin, J.3
Pollock, R.A.4
Kalusek, F.5
Neupert, W.6
Hallberg, E.M.7
Hallberg, R.L.8
Horwich, A.L.9
-
57
-
-
0024972079
-
Characterization of the yeast HSP60 gene coding for a mitochondrial assembly factor
-
Reading D.S., Hallberg R.L., Myers A.M. Characterization of the yeast HSP60 gene coding for a mitochondrial assembly factor. Nature 1989, 337:655-659.
-
(1989)
Nature
, vol.337
, pp. 655-659
-
-
Reading, D.S.1
Hallberg, R.L.2
Myers, A.M.3
-
58
-
-
0024458504
-
Protein folding in mitochondria requires complex formation with hsp60 and ATP hydrolysis
-
Ostermann J., Horwich A.L., Neupert W., Hartl F.U. Protein folding in mitochondria requires complex formation with hsp60 and ATP hydrolysis. Nature 1989, 341:125-130.
-
(1989)
Nature
, vol.341
, pp. 125-130
-
-
Ostermann, J.1
Horwich, A.L.2
Neupert, W.3
Hartl, F.U.4
-
59
-
-
0032113635
-
A single ring is sufficient for productive chaperonin-mediated folding in vivo
-
Nielsen K.L., Cowan N.J. A single ring is sufficient for productive chaperonin-mediated folding in vivo. Mol. Cell 1998, 2:93-99.
-
(1998)
Mol. Cell
, vol.2
, pp. 93-99
-
-
Nielsen, K.L.1
Cowan, N.J.2
-
60
-
-
0031896846
-
Directionality of polypeptide transfer in the mitochondrial pathway of chaperone-mediated protein folding
-
Heyrovska N., Frydman J., Höhfeld J., Hartl F.U. Directionality of polypeptide transfer in the mitochondrial pathway of chaperone-mediated protein folding. Biol. Chem. 1998, 379:301-309.
-
(1998)
Biol. Chem.
, vol.379
, pp. 301-309
-
-
Heyrovska, N.1
Frydman, J.2
Höhfeld, J.3
Hartl, F.U.4
-
61
-
-
0030063416
-
Hsp60-independent protein folding in the matrix of yeast mitochondria
-
Rospert S., Looser R., Dubaquié Y., Matouschek A., Glick B.S., Schatz G. Hsp60-independent protein folding in the matrix of yeast mitochondria. EMBO J. 1996, 15:764-774.
-
(1996)
EMBO J.
, vol.15
, pp. 764-774
-
-
Rospert, S.1
Looser, R.2
Dubaquié, Y.3
Matouschek, A.4
Glick, B.S.5
Schatz, G.6
-
62
-
-
0032531727
-
Identification of in vivo substrates of the yeast mitochondrial chaperonins reveals overlapping but non-identical requirement for hsp60 and hsp10
-
Dubaquie Y., Looser R., Fünfschilling U., Jenö P., Rospert S. Identification of in vivo substrates of the yeast mitochondrial chaperonins reveals overlapping but non-identical requirement for hsp60 and hsp10. EMBO J. 1998, 17:5868-5876.
-
(1998)
EMBO J.
, vol.17
, pp. 5868-5876
-
-
Dubaquie, Y.1
Looser, R.2
Fünfschilling, U.3
Jenö, P.4
Rospert, S.5
-
63
-
-
0033582380
-
Two distinct mechanisms operate in the reactivation of heat-denatured proteins by the mitochondrial Hsp70/Mdj1p/Yge1p chaperone system
-
Kubo Y., Tsunehiro T., Nishikawa S., Nakai M., Ikeda E., Toh-e A., Morishima N., Shibata T., Endo T. Two distinct mechanisms operate in the reactivation of heat-denatured proteins by the mitochondrial Hsp70/Mdj1p/Yge1p chaperone system. J. Mol. Biol. 1999, 286:447-464.
-
(1999)
J. Mol. Biol.
, vol.286
, pp. 447-464
-
-
Kubo, Y.1
Tsunehiro, T.2
Nishikawa, S.3
Nakai, M.4
Ikeda, E.5
Toh-e, A.6
Morishima, N.7
Shibata, T.8
Endo, T.9
-
64
-
-
0030040712
-
Role of the mitochondrial DnaJ homologue, Mdj1p, in the prevention of heat-induced protein aggregation
-
Prip-Buus C., Westermann B., Schmitt M., Langer T., Neupert W., Schwarz E. Role of the mitochondrial DnaJ homologue, Mdj1p, in the prevention of heat-induced protein aggregation. FEBS Lett. 1996, 380:142-146.
-
(1996)
FEBS Lett.
, vol.380
, pp. 142-146
-
-
Prip-Buus, C.1
Westermann, B.2
Schmitt, M.3
Langer, T.4
Neupert, W.5
Schwarz, E.6
-
65
-
-
79952328398
-
Mitochondrial enzymes are protected from stress-induced aggregation by mitochondrial chaperones and the Pim1/LON protease
-
Bender T., Lewrenz I., Franken S., Baitzel C., Voos W. Mitochondrial enzymes are protected from stress-induced aggregation by mitochondrial chaperones and the Pim1/LON protease. Mol. Biol. Cell 2011, 22:541-554.
-
(2011)
Mol. Biol. Cell
, vol.22
, pp. 541-554
-
-
Bender, T.1
Lewrenz, I.2
Franken, S.3
Baitzel, C.4
Voos, W.5
-
66
-
-
0027946910
-
Molecular chaperones cooperate with PIM1 protease in the degradation of misfolded proteins in mitochondria
-
Wagner I., Arlt H., van Dyck L., Langer T., Neupert W. Molecular chaperones cooperate with PIM1 protease in the degradation of misfolded proteins in mitochondria. EMBO J. 1994, 13:5135-5145.
-
(1994)
EMBO J.
, vol.13
, pp. 5135-5145
-
-
Wagner, I.1
Arlt, H.2
van Dyck, L.3
Langer, T.4
Neupert, W.5
-
67
-
-
34247171756
-
Knockdown of mitochondrial heat shock protein 70 promotes progeria-like phenotypes in Caenorhabditis elegans
-
Kimura K., Tanaka N., Nakamura N., Takano S., Ohkuma S. Knockdown of mitochondrial heat shock protein 70 promotes progeria-like phenotypes in Caenorhabditis elegans. J. Biol. Chem. 2007, 282:5910-5918.
-
(2007)
J. Biol. Chem.
, vol.282
, pp. 5910-5918
-
-
Kimura, K.1
Tanaka, N.2
Nakamura, N.3
Takano, S.4
Ohkuma, S.5
-
68
-
-
34249741418
-
Involvement of mortalin in cellular senescence from the perspective of its mitochondrial import, chaperone, and oxidative stress management functions
-
Yaguchi T., Aida S., Kaul S.C., Wadhwa R. Involvement of mortalin in cellular senescence from the perspective of its mitochondrial import, chaperone, and oxidative stress management functions. Ann. N. Y. Acad. Sci. 2007, 1100:306-311.
-
(2007)
Ann. N. Y. Acad. Sci.
, vol.1100
, pp. 306-311
-
-
Yaguchi, T.1
Aida, S.2
Kaul, S.C.3
Wadhwa, R.4
-
69
-
-
33746296891
-
Proteomic identification of a stress protein, mortalin/mthsp70/GRP75: relevance to Parkinson disease
-
Jin J., Hulette C., Wang Y., Zhang T., Pan C., Wadhwa R., Zhang J. Proteomic identification of a stress protein, mortalin/mthsp70/GRP75: relevance to Parkinson disease. Mol. Cell. Proteomics 2006, 5:1193-1204.
-
(2006)
Mol. Cell. Proteomics
, vol.5
, pp. 1193-1204
-
-
Jin, J.1
Hulette, C.2
Wang, Y.3
Zhang, T.4
Pan, C.5
Wadhwa, R.6
Zhang, J.7
-
70
-
-
0027294734
-
Loss of mitochondrial hsp60 function: nonequivalent effects on matrix-targeted and intermembrane-targeted proteins
-
Hallberg E.M., Shu Y., Hallberg R.L. Loss of mitochondrial hsp60 function: nonequivalent effects on matrix-targeted and intermembrane-targeted proteins. Mol. Cell. Biol. 1993, 13:3050-3057.
-
(1993)
Mol. Cell. Biol.
, vol.13
, pp. 3050-3057
-
-
Hallberg, E.M.1
Shu, Y.2
Hallberg, R.L.3
-
71
-
-
0036138947
-
A subset of newly synthesized polypeptides in mitochondria from human endothelial cells exposed to hydroperoxide stress
-
Mitsumoto A., Takeuchi A., Okawa K., Nakagawa Y. A subset of newly synthesized polypeptides in mitochondria from human endothelial cells exposed to hydroperoxide stress. Free Radic. Biol. Med. 2002, 32:22-37.
-
(2002)
Free Radic. Biol. Med.
, vol.32
, pp. 22-37
-
-
Mitsumoto, A.1
Takeuchi, A.2
Okawa, K.3
Nakagawa, Y.4
-
72
-
-
0037009521
-
A mitochondrial specific stress response in mammalian cells
-
Zhao Q., Wang J., Levichkin I.V., Stasinopoulos S., Ryan M.T., Hoogenraad N.J. A mitochondrial specific stress response in mammalian cells. EMBO J. 2002, 21:4411-4419.
-
(2002)
EMBO J.
, vol.21
, pp. 4411-4419
-
-
Zhao, Q.1
Wang, J.2
Levichkin, I.V.3
Stasinopoulos, S.4
Ryan, M.T.5
Hoogenraad, N.J.6
-
73
-
-
4944234936
-
Compartment-specific perturbation of protein handling activates genes encoding mitochondrial chaperones
-
Yoneda T., Benedetti C., Urano F., Clark S.G., Harding H.P., Ron D. Compartment-specific perturbation of protein handling activates genes encoding mitochondrial chaperones. J. Cell Sci. 2004, 117:4055-4066.
-
(2004)
J. Cell Sci.
, vol.117
, pp. 4055-4066
-
-
Yoneda, T.1
Benedetti, C.2
Urano, F.3
Clark, S.G.4
Harding, H.P.5
Ron, D.6
-
74
-
-
43049159563
-
Decreased expression of the mitochondrial matrix proteases Lon and ClpP in cells from a patient with hereditary spastic paraplegia (SPG13)
-
Hansen J., Corydon T.J., Palmfeldt J., Durr A., Fontaine B., Nielsen M.N., Christensen J.H., Gregersen N., Bross P. Decreased expression of the mitochondrial matrix proteases Lon and ClpP in cells from a patient with hereditary spastic paraplegia (SPG13). Neuroscience 2008, 153:474-482.
-
(2008)
Neuroscience
, vol.153
, pp. 474-482
-
-
Hansen, J.1
Corydon, T.J.2
Palmfeldt, J.3
Durr, A.4
Fontaine, B.5
Nielsen, M.N.6
Christensen, J.H.7
Gregersen, N.8
Bross, P.9
-
75
-
-
0347481388
-
Misfolding, degradation, and aggregation of variant proteins. The molecular pathogenesis of short chain acyl-CoA dehydrogenase (SCAD) deficiency
-
Pedersen C.B., Bross P., Winter V.S., Corydon T.J., Bolund L., Bartlett K., Vockley J., Gregersen N. Misfolding, degradation, and aggregation of variant proteins. The molecular pathogenesis of short chain acyl-CoA dehydrogenase (SCAD) deficiency. J. Biol. Chem. 2003, 278:47449-47458.
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 47449-47458
-
-
Pedersen, C.B.1
Bross, P.2
Winter, V.S.3
Corydon, T.J.4
Bolund, L.5
Bartlett, K.6
Vockley, J.7
Gregersen, N.8
-
76
-
-
58149181486
-
Hsp104 and ClpB: protein disaggregating machines
-
Doyle S.M., Wickner S. Hsp104 and ClpB: protein disaggregating machines. Trends Biochem. Sci. 2009, 34:40-48.
-
(2009)
Trends Biochem. Sci.
, vol.34
, pp. 40-48
-
-
Doyle, S.M.1
Wickner, S.2
-
77
-
-
84855207518
-
The elusive middle domain of Hsp104 and ClpB: location and function
-
Desantis M.E., Shorter J. The elusive middle domain of Hsp104 and ClpB: location and function. Biochim. Biophys. Acta 2012, 1823:29-39.
-
(2012)
Biochim. Biophys. Acta
, vol.1823
, pp. 29-39
-
-
Desantis, M.E.1
Shorter, J.2
-
78
-
-
0035783169
-
Mechanisms of disaggregation and refolding of stable protein aggregates by molecular chaperones
-
Ben-Zvi A.P., Goloubinoff P. Mechanisms of disaggregation and refolding of stable protein aggregates by molecular chaperones. J. Struct. Biol. 2001, 135:84-93.
-
(2001)
J. Struct. Biol.
, vol.135
, pp. 84-93
-
-
Ben-Zvi, A.P.1
Goloubinoff, P.2
-
79
-
-
1642361660
-
The ClpB/Hsp104 molecular chaperone-a protein disaggregating machine
-
Lee S., Sowa M.E., Choi J.M., Tsai F.T. The ClpB/Hsp104 molecular chaperone-a protein disaggregating machine. J. Struct. Biol. 2004, 146:99-105.
-
(2004)
J. Struct. Biol.
, vol.146
, pp. 99-105
-
-
Lee, S.1
Sowa, M.E.2
Choi, J.M.3
Tsai, F.T.4
-
80
-
-
44849138934
-
Protein disaggregation by the AAA+ chaperone ClpB involves partial threading of looped polypeptide segments
-
Haslberger T., Zdanowicz A., Brand I., Kirstein J., Turgay K., Mogk A., Bukau B. Protein disaggregation by the AAA+ chaperone ClpB involves partial threading of looped polypeptide segments. Nat. Struct. Mol. Biol. 2008, 15:641-650.
-
(2008)
Nat. Struct. Mol. Biol.
, vol.15
, pp. 641-650
-
-
Haslberger, T.1
Zdanowicz, A.2
Brand, I.3
Kirstein, J.4
Turgay, K.5
Mogk, A.6
Bukau, B.7
-
81
-
-
8844251486
-
Thermotolerance requires refolding of aggregated proteins by substrate translocation through the central pore of ClpB
-
Weibezahn J., Tessarz P., Schlieker C., Zahn R., Maglica Z., Lee S., Zentgraf H., Weber-Ban E.U., Dougan D.A., Tsai F.T., Mogk A., Bukau B. Thermotolerance requires refolding of aggregated proteins by substrate translocation through the central pore of ClpB. Cell 2004, 119:653-665.
-
(2004)
Cell
, vol.119
, pp. 653-665
-
-
Weibezahn, J.1
Tessarz, P.2
Schlieker, C.3
Zahn, R.4
Maglica, Z.5
Lee, S.6
Zentgraf, H.7
Weber-Ban, E.U.8
Dougan, D.A.9
Tsai, F.T.10
Mogk, A.11
Bukau, B.12
-
82
-
-
0027445711
-
HSP78 encodes a yeast mitochondrial heat shock protein in the Clp family of ATP-dependent proteases
-
Leonhardt S.A., Fearon K., Danese P.N., Mason T.L. HSP78 encodes a yeast mitochondrial heat shock protein in the Clp family of ATP-dependent proteases. Mol. Cell. Biol. 1993, 13:6304-6313.
-
(1993)
Mol. Cell. Biol.
, vol.13
, pp. 6304-6313
-
-
Leonhardt, S.A.1
Fearon, K.2
Danese, P.N.3
Mason, T.L.4
-
83
-
-
33749234536
-
Structure and function of Hsp78, the mitochondrial ClpB homolog
-
Leidhold C., Janowsky B.V., Becker D., Bender T., Voos W. Structure and function of Hsp78, the mitochondrial ClpB homolog. J. Struct. Biol. 2006, 156:149-164.
-
(2006)
J. Struct. Biol.
, vol.156
, pp. 149-164
-
-
Leidhold, C.1
Janowsky, B.V.2
Becker, D.3
Bender, T.4
Voos, W.5
-
84
-
-
0035824878
-
Importance of two ATP-binding sites for oligomerization, ATPase activity and chaperone function of mitochondrial Hsp78 protein
-
Krzewska J., Konopa G., Liberek K. Importance of two ATP-binding sites for oligomerization, ATPase activity and chaperone function of mitochondrial Hsp78 protein. J. Mol. Biol. 2001, 314:901-910.
-
(2001)
J. Mol. Biol.
, vol.314
, pp. 901-910
-
-
Krzewska, J.1
Konopa, G.2
Liberek, K.3
-
85
-
-
0029835946
-
The molecular chaperone Hsp78 confers compartment-specific thermotolerance to mitochondria
-
Schmitt M., Neupert W., Langer T. The molecular chaperone Hsp78 confers compartment-specific thermotolerance to mitochondria. J. Cell Biol. 1996, 134:1375-1386.
-
(1996)
J. Cell Biol.
, vol.134
, pp. 1375-1386
-
-
Schmitt, M.1
Neupert, W.2
Langer, T.3
-
86
-
-
0037008763
-
A bichaperone (Hsp70-Hsp78) system restores mitochondrial DNA synthesis following thermal inactivation of Mip1p polymerase
-
Germaniuk A., Liberek K., Marszalek J. A bichaperone (Hsp70-Hsp78) system restores mitochondrial DNA synthesis following thermal inactivation of Mip1p polymerase. J. Biol. Chem. 2002, 277:27801-27808.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 27801-27808
-
-
Germaniuk, A.1
Liberek, K.2
Marszalek, J.3
-
87
-
-
33644972955
-
Hsp78 chaperone functions in restoration of mitochondrial network following heat stress
-
Lewandowska A., Gierszewska M., Marszalek J., Liberek K. Hsp78 chaperone functions in restoration of mitochondrial network following heat stress. Biochim. Biophys. Acta 2006, 1763:141-151.
-
(2006)
Biochim. Biophys. Acta
, vol.1763
, pp. 141-151
-
-
Lewandowska, A.1
Gierszewska, M.2
Marszalek, J.3
Liberek, K.4
-
88
-
-
0035951385
-
Mitochondrial Hsp78, a member of the Clp/Hsp100 family in Saccharomyces cerevisiae, cooperates with Hsp70 in protein refolding
-
Krzewska J., Langer T., Liberek K. Mitochondrial Hsp78, a member of the Clp/Hsp100 family in Saccharomyces cerevisiae, cooperates with Hsp70 in protein refolding. FEBS Lett. 2001, 489:92-96.
-
(2001)
FEBS Lett.
, vol.489
, pp. 92-96
-
-
Krzewska, J.1
Langer, T.2
Liberek, K.3
-
89
-
-
0029583429
-
The mitochondrial ClpB homolog Hsp78 cooperates with matrix Hsp70 in maintenance of mitochondrial function
-
Moczko M., Schönfisch B., Voos W., Pfanner N., Rassow J. The mitochondrial ClpB homolog Hsp78 cooperates with matrix Hsp70 in maintenance of mitochondrial function. J. Mol. Biol. 1995, 254:538-543.
-
(1995)
J. Mol. Biol.
, vol.254
, pp. 538-543
-
-
Moczko, M.1
Schönfisch, B.2
Voos, W.3
Pfanner, N.4
Rassow, J.5
-
90
-
-
33644951058
-
The disaggregation activity of the mitochondrial ClpB homolog Hsp78 maintains Hsp70 function during heat stress
-
von Janowsky B., Major T., Knapp K., Voos W. The disaggregation activity of the mitochondrial ClpB homolog Hsp78 maintains Hsp70 function during heat stress. J. Mol. Biol. 2006, 357:793-807.
-
(2006)
J. Mol. Biol.
, vol.357
, pp. 793-807
-
-
von Janowsky, B.1
Major, T.2
Knapp, K.3
Voos, W.4
-
91
-
-
4444288866
-
Active solubilization and refolding of stable protein aggregates by cooperative unfolding action of individual hsp70 chaperones
-
Ben-Zvi A., De Los Rios P., Dietler G., Goloubinoff P. Active solubilization and refolding of stable protein aggregates by cooperative unfolding action of individual hsp70 chaperones. J. Biol. Chem. 2004, 279:37298-37303.
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 37298-37303
-
-
Ben-Zvi, A.1
De Los Rios, P.2
Dietler, G.3
Goloubinoff, P.4
-
92
-
-
84858955705
-
Reactivation of protein aggregates by mortalin and Tid1-the human mitochondrial Hsp70 chaperone system
-
Iosefson O., Sharon S., Goloubinoff P., Azem A. Reactivation of protein aggregates by mortalin and Tid1-the human mitochondrial Hsp70 chaperone system. Cell Stress Chaperones 2012, 17:57-66.
-
(2012)
Cell Stress Chaperones
, vol.17
, pp. 57-66
-
-
Iosefson, O.1
Sharon, S.2
Goloubinoff, P.3
Azem, A.4
-
93
-
-
1842457138
-
The ClpB homolog Hsp78 is required for the efficient degradation of proteins in the mitochondrial matrix
-
Röttgers K., Zufall N., Guiard B., Voos W. The ClpB homolog Hsp78 is required for the efficient degradation of proteins in the mitochondrial matrix. J. Biol. Chem. 2002, 277:45829-45837.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 45829-45837
-
-
Röttgers, K.1
Zufall, N.2
Guiard, B.3
Voos, W.4
-
94
-
-
0037033115
-
Mitochondrial DNA instability mutants of the bifunctional protein Ilv5p have altered organization in mitochondria and are targeted for degradation by Hsp78 and the Pim1p protease
-
Bateman J.M., Iacovino M., Perlman P.S., Butow R.A. Mitochondrial DNA instability mutants of the bifunctional protein Ilv5p have altered organization in mitochondria and are targeted for degradation by Hsp78 and the Pim1p protease. J. Biol. Chem. 2002, 277:47946-47953.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 47946-47953
-
-
Bateman, J.M.1
Iacovino, M.2
Perlman, P.S.3
Butow, R.A.4
-
95
-
-
0022360054
-
The role of ATP hydrolysis in the breakdown of proteins and peptides by protease La from Escherichia coli
-
Goldberg A.L., Waxman L. The role of ATP hydrolysis in the breakdown of proteins and peptides by protease La from Escherichia coli. J. Biol. Chem. 1985, 260:12029-12034.
-
(1985)
J. Biol. Chem.
, vol.260
, pp. 12029-12034
-
-
Goldberg, A.L.1
Waxman, L.2
-
96
-
-
77958477536
-
Crystal structure of Lon protease: molecular architecture of gated entry to a sequestered degradation chamber
-
Cha S.S., An Y.J., Lee C.R., Lee H.S., Kim Y.G., Kim S.J., Kwon K.K., De Donatis G.M., Lee J.H., Maurizi M.R., Kang S.G. Crystal structure of Lon protease: molecular architecture of gated entry to a sequestered degradation chamber. EMBO J. 2010, 29:3520-3530.
-
(2010)
EMBO J.
, vol.29
, pp. 3520-3530
-
-
Cha, S.S.1
An, Y.J.2
Lee, C.R.3
Lee, H.S.4
Kim, Y.G.5
Kim, S.J.6
Kwon, K.K.7
De Donatis, G.M.8
Lee, J.H.9
Maurizi, M.R.10
Kang, S.G.11
-
97
-
-
10744225162
-
The catalytic domain of Escherichia coli Lon protease has a unique fold and a Ser-Lys dyad in the active site
-
Botos I., Melnikov E.E., Cherry S., Tropea J.E., Khalatova A.G., Rasulova F., Dauter Z., Maurizi M.R., Rotanova T.V., Wlodawer A., Gustchina A. The catalytic domain of Escherichia coli Lon protease has a unique fold and a Ser-Lys dyad in the active site. J. Biol. Chem. 2004, 279:8140-8148.
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 8140-8148
-
-
Botos, I.1
Melnikov, E.E.2
Cherry, S.3
Tropea, J.E.4
Khalatova, A.G.5
Rasulova, F.6
Dauter, Z.7
Maurizi, M.R.8
Rotanova, T.V.9
Wlodawer, A.10
Gustchina, A.11
-
98
-
-
0020479616
-
Demonstration of an ATP-dependent, vanadate-sensitive endoprotease in the matrix of rat liver mitochondria
-
Desautels M., Goldberg A.L. Demonstration of an ATP-dependent, vanadate-sensitive endoprotease in the matrix of rat liver mitochondria. J. Biol. Chem. 1982, 257:11673-11679.
-
(1982)
J. Biol. Chem.
, vol.257
, pp. 11673-11679
-
-
Desautels, M.1
Goldberg, A.L.2
-
99
-
-
0028362456
-
Requirement for the yeast gene LON in intramitochondrial proteolysis and maintenance of respiration
-
Suzuki C.K., Suda K., Wang N., Schatz G. Requirement for the yeast gene LON in intramitochondrial proteolysis and maintenance of respiration. Science 1994, 264:273-276.
-
(1994)
Science
, vol.264
, pp. 273-276
-
-
Suzuki, C.K.1
Suda, K.2
Wang, N.3
Schatz, G.4
-
100
-
-
0028049082
-
PIM1 encodes a mitochondrial ATP-dependent protease that is required for mitochondrial function in the yeast Saccharomyces cerevisiae
-
van Dyck L., Pearce D.A., Sherman F. PIM1 encodes a mitochondrial ATP-dependent protease that is required for mitochondrial function in the yeast Saccharomyces cerevisiae. J. Biol. Chem. 1994, 269:238-242.
-
(1994)
J. Biol. Chem.
, vol.269
, pp. 238-242
-
-
van Dyck, L.1
Pearce, D.A.2
Sherman, F.3
-
101
-
-
15744384860
-
Downregulation of the human Lon protease impairs mitochondrial structure and function and causes cell death
-
Bota D.A., Ngo J.K., Davies K.J. Downregulation of the human Lon protease impairs mitochondrial structure and function and causes cell death. Free Radic. Biol. Med. 2005, 38:665-677.
-
(2005)
Free Radic. Biol. Med.
, vol.38
, pp. 665-677
-
-
Bota, D.A.1
Ngo, J.K.2
Davies, K.J.3
-
102
-
-
0036713692
-
Lon protease preferentially degrades oxidized mitochondrial aconitase by an ATP-stimulated mechanism
-
Bota D.A., Davies K.J. Lon protease preferentially degrades oxidized mitochondrial aconitase by an ATP-stimulated mechanism. Nat. Cell Biol. 2002, 4:674-680.
-
(2002)
Nat. Cell Biol.
, vol.4
, pp. 674-680
-
-
Bota, D.A.1
Davies, K.J.2
-
103
-
-
31344455097
-
Proteomic analysis of mitochondrial protein turnover: identification of novel substrate proteins of the matrix protease Pim1
-
Major T., von Janowsky B., Ruppert T., Mogk A., Voos W. Proteomic analysis of mitochondrial protein turnover: identification of novel substrate proteins of the matrix protease Pim1. Mol. Cell. Biol. 2006, 26:762-776.
-
(2006)
Mol. Cell. Biol.
, vol.26
, pp. 762-776
-
-
Major, T.1
von Janowsky, B.2
Ruppert, T.3
Mogk, A.4
Voos, W.5
-
104
-
-
77950676470
-
The role of protein quality control in mitochondrial protein homeostasis under oxidative stress
-
Bender T., Leidhold C., Ruppert T., Franken S., Voos W. The role of protein quality control in mitochondrial protein homeostasis under oxidative stress. Proteomics 2010, 10:1426-1443.
-
(2010)
Proteomics
, vol.10
, pp. 1426-1443
-
-
Bender, T.1
Leidhold, C.2
Ruppert, T.3
Franken, S.4
Voos, W.5
-
105
-
-
77951216461
-
Identification of novel oxidized protein substrates and physiological partners of the mitochondrial ATP-dependent Lon-like protease Pim1
-
Bayot A., Gareil M., Rogowska-Wrzesinska A., Roepstorff P., Friguet B., Bulteau A.L. Identification of novel oxidized protein substrates and physiological partners of the mitochondrial ATP-dependent Lon-like protease Pim1. J. Biol. Chem. 2010, 285:11445-114457.
-
(2010)
J. Biol. Chem.
, vol.285
, pp. 11445-114457
-
-
Bayot, A.1
Gareil, M.2
Rogowska-Wrzesinska, A.3
Roepstorff, P.4
Friguet, B.5
Bulteau, A.L.6
-
106
-
-
29044432842
-
Structural properties of substrate proteins determine their proteolysis by the mitochondrial AAA+ protease Pim1
-
von Janowsky B., Knapp K., Major T., Krayl M., Guiard B., Voos W. Structural properties of substrate proteins determine their proteolysis by the mitochondrial AAA+ protease Pim1. Biol. Chem. 2005, 386:1307-1317.
-
(2005)
Biol. Chem.
, vol.386
, pp. 1307-1317
-
-
von Janowsky, B.1
Knapp, K.2
Major, T.3
Krayl, M.4
Guiard, B.5
Voos, W.6
-
107
-
-
21644454699
-
Cleavage site selection within a folded substrate by the ATP-dependent lon protease
-
Ondrovicova G., Liu T., Singh K., Tian B., Li H., Gakh O., Perecko D., Janata J., Granot Z., Orly J., Kutejova E., Suzuki C.K. Cleavage site selection within a folded substrate by the ATP-dependent lon protease. J. Biol. Chem. 2005, 280:25103-25110.
-
(2005)
J. Biol. Chem.
, vol.280
, pp. 25103-25110
-
-
Ondrovicova, G.1
Liu, T.2
Singh, K.3
Tian, B.4
Li, H.5
Gakh, O.6
Perecko, D.7
Janata, J.8
Granot, Z.9
Orly, J.10
Kutejova, E.11
Suzuki, C.K.12
-
108
-
-
0344211512
-
Lack of a robust unfoldase activity confers a unique level of substrate specificity to the universal AAA protease FtsH
-
Herman C., Prakash S., Lu C.Z., Matouschek A., Gross C.A. Lack of a robust unfoldase activity confers a unique level of substrate specificity to the universal AAA protease FtsH. Mol. Cell 2003, 11:659-669.
-
(2003)
Mol. Cell
, vol.11
, pp. 659-669
-
-
Herman, C.1
Prakash, S.2
Lu, C.Z.3
Matouschek, A.4
Gross, C.A.5
-
109
-
-
0029762950
-
Promotion of mitochondrial membrane complex assembly by a proteolytically inactive yeast Lon
-
Rep M., van Dijl J.M., Suda K., Schatz G., Grivell L.A., Suzuki C.K. Promotion of mitochondrial membrane complex assembly by a proteolytically inactive yeast Lon. Science 1996, 274:103-106.
-
(1996)
Science
, vol.274
, pp. 103-106
-
-
Rep, M.1
van Dijl, J.M.2
Suda, K.3
Schatz, G.4
Grivell, L.A.5
Suzuki, C.K.6
-
110
-
-
0032168771
-
The ATPase and protease domains of yeast mitochondrial Lon: roles in proteolysis and respiration-dependent growth
-
van Dijl J.M., Kutejova E., Suda K., Perecko D., Schatz G., Suzuki C.K. The ATPase and protease domains of yeast mitochondrial Lon: roles in proteolysis and respiration-dependent growth. Proc. Natl. Acad. Sci. U. S. A. 1998, 95:10584-10589.
-
(1998)
Proc. Natl. Acad. Sci. U. S. A.
, vol.95
, pp. 10584-10589
-
-
van Dijl, J.M.1
Kutejova, E.2
Suda, K.3
Perecko, D.4
Schatz, G.5
Suzuki, C.K.6
-
111
-
-
0032523778
-
The ATP-dependent PIM1 protease is required for the expression of intron-containing genes in mitochondria
-
van Dyck L., Neupert W., Langer T. The ATP-dependent PIM1 protease is required for the expression of intron-containing genes in mitochondria. Genes Dev. 1998, 12:1515-1524.
-
(1998)
Genes Dev.
, vol.12
, pp. 1515-1524
-
-
van Dyck, L.1
Neupert, W.2
Langer, T.3
-
112
-
-
0037434941
-
The ATP-dependent Lon protease of Mus musculus is a DNA-binding protein that is functionally conserved between yeast and mammals
-
Lu B., Liu T., Crosby J.A., Thomas-Wohlever J., Lee I., Suzuki C.K. The ATP-dependent Lon protease of Mus musculus is a DNA-binding protein that is functionally conserved between yeast and mammals. Gene 2003, 306:45-55.
-
(2003)
Gene
, vol.306
, pp. 45-55
-
-
Lu, B.1
Liu, T.2
Crosby, J.A.3
Thomas-Wohlever, J.4
Lee, I.5
Suzuki, C.K.6
-
113
-
-
1842690145
-
DNA and RNA binding by the mitochondrial lon protease is regulated by nucleotide and protein substrate
-
Liu T., Lu B., Lee I., Ondrovicova G., Kutejova E., Suzuki C.K. DNA and RNA binding by the mitochondrial lon protease is regulated by nucleotide and protein substrate. J. Biol. Chem. 2004, 279:13902-13910.
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 13902-13910
-
-
Liu, T.1
Lu, B.2
Lee, I.3
Ondrovicova, G.4
Kutejova, E.5
Suzuki, C.K.6
-
114
-
-
34547117627
-
Roles for the human ATP-dependent Lon protease in mitochondrial DNA maintenance
-
Lu B., Yadav S., Shah P.G., Liu T., Tian B., Pukszta S., Villaluna N., Kutejova E., Newlon C.S., Santos J.H., Suzuki C.K. Roles for the human ATP-dependent Lon protease in mitochondrial DNA maintenance. J. Biol. Chem. 2007, 282:17363-17374.
-
(2007)
J. Biol. Chem.
, vol.282
, pp. 17363-17374
-
-
Lu, B.1
Yadav, S.2
Shah, P.G.3
Liu, T.4
Tian, B.5
Pukszta, S.6
Villaluna, N.7
Kutejova, E.8
Newlon, C.S.9
Santos, J.H.10
Suzuki, C.K.11
-
115
-
-
67651208925
-
Adapting the machine: adaptor proteins for Hsp100/Clp and AAA+ proteases
-
Kirstein J., Moliere N., Dougan D.A., Turgay K. Adapting the machine: adaptor proteins for Hsp100/Clp and AAA+ proteases. Nat. Rev. Microbiol. 2009, 7:589-599.
-
(2009)
Nat. Rev. Microbiol.
, vol.7
, pp. 589-599
-
-
Kirstein, J.1
Moliere, N.2
Dougan, D.A.3
Turgay, K.4
-
116
-
-
84855195754
-
ClpXP, an ATP-powered unfolding and protein-degradation machine
-
Baker T.A., Sauer R.T. ClpXP, an ATP-powered unfolding and protein-degradation machine. Biochim. Biophys. Acta 2012, 1823:15-28.
-
(2012)
Biochim. Biophys. Acta
, vol.1823
, pp. 15-28
-
-
Baker, T.A.1
Sauer, R.T.2
-
117
-
-
0032079329
-
The ClpXP and ClpAP proteases degrade proteins with carboxy-terminal peptide tails added by the SsrA-tagging system
-
Gottesman S., Roche E., Zhou Y., Sauer R.T. The ClpXP and ClpAP proteases degrade proteins with carboxy-terminal peptide tails added by the SsrA-tagging system. Genes Dev. 1998, 12:1338-1347.
-
(1998)
Genes Dev.
, vol.12
, pp. 1338-1347
-
-
Gottesman, S.1
Roche, E.2
Zhou, Y.3
Sauer, R.T.4
-
118
-
-
0031737552
-
Mcx1p, a ClpX homologue in mitochondria of Saccharomyces cerevisiae
-
van Dyck L., Dembowski M., Neupert W., Langer T. Mcx1p, a ClpX homologue in mitochondria of Saccharomyces cerevisiae. FEBS Lett. 1998, 438:250-254.
-
(1998)
FEBS Lett.
, vol.438
, pp. 250-254
-
-
van Dyck, L.1
Dembowski, M.2
Neupert, W.3
Langer, T.4
-
119
-
-
0029620843
-
Human ClpP protease: cDNA sequence, tissue-specific expression and chromosomal assignment of the gene
-
Bross P., Andresen B.S., Knudsen I., Kruse T.A., Gregersen N. Human ClpP protease: cDNA sequence, tissue-specific expression and chromosomal assignment of the gene. FEBS Lett. 1995, 377:249-252.
-
(1995)
FEBS Lett.
, vol.377
, pp. 249-252
-
-
Bross, P.1
Andresen, B.S.2
Knudsen, I.3
Kruse, T.A.4
Gregersen, N.5
-
120
-
-
7444254844
-
Crystallography and mutagenesis point to an essential role for the N-terminus of human mitochondrial ClpP
-
Kang S.G., Maurizi M.R., Thompson M., Mueser T., Ahvazi B. Crystallography and mutagenesis point to an essential role for the N-terminus of human mitochondrial ClpP. J. Struct. Biol. 2004, 148:338-352.
-
(2004)
J. Struct. Biol.
, vol.148
, pp. 338-352
-
-
Kang, S.G.1
Maurizi, M.R.2
Thompson, M.3
Mueser, T.4
Ahvazi, B.5
-
121
-
-
27444440627
-
Human mitochondrial ClpP is a stable heptamer that assembles into a tetradecamer in the presence of ClpX
-
Kang S.G., Dimitrova M.N., Ortega J., Ginsburg A., Maurizi M.R. Human mitochondrial ClpP is a stable heptamer that assembles into a tetradecamer in the presence of ClpX. J. Biol. Chem. 2005, 280:35424-35432.
-
(2005)
J. Biol. Chem.
, vol.280
, pp. 35424-35432
-
-
Kang, S.G.1
Dimitrova, M.N.2
Ortega, J.3
Ginsburg, A.4
Maurizi, M.R.5
-
122
-
-
0037036431
-
Functional proteolytic complexes of the human mitochondrial ATP-dependent protease, hClpXP
-
Kang S.G., Ortega J., Singh S.K., Wang N., Huang N.N., Steven A.C., Maurizi M.R. Functional proteolytic complexes of the human mitochondrial ATP-dependent protease, hClpXP. J. Biol. Chem. 2002, 277:21095-21102.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 21095-21102
-
-
Kang, S.G.1
Ortega, J.2
Singh, S.K.3
Wang, N.4
Huang, N.N.5
Steven, A.C.6
Maurizi, M.R.7
-
123
-
-
82255173966
-
The unfolded protein response: from stress pathway to homeostatic regulation
-
Walter P., Ron D. The unfolded protein response: from stress pathway to homeostatic regulation. Science 2011, 334:1081-1086.
-
(2011)
Science
, vol.334
, pp. 1081-1086
-
-
Walter, P.1
Ron, D.2
-
124
-
-
34848861368
-
ClpP mediates activation of a mitochondrial unfolded protein response in C. elegans
-
Haynes C.M., Petrova K., Benedetti C., Yang Y., Ron D. ClpP mediates activation of a mitochondrial unfolded protein response in C. elegans. Dev. Cell 2007, 13:467-480.
-
(2007)
Dev. Cell
, vol.13
, pp. 467-480
-
-
Haynes, C.M.1
Petrova, K.2
Benedetti, C.3
Yang, Y.4
Ron, D.5
-
125
-
-
76849100919
-
The matrix peptide exporter HAF-1 signals a mitochondrial UPR by activating the transcription factor ZC376.7 in C. elegans
-
Haynes C.M., Yang Y., Blais S.P., Neubert T.A., Ron D. The matrix peptide exporter HAF-1 signals a mitochondrial UPR by activating the transcription factor ZC376.7 in C. elegans. Mol. Cell 2010, 37:529-540.
-
(2010)
Mol. Cell
, vol.37
, pp. 529-540
-
-
Haynes, C.M.1
Yang, Y.2
Blais, S.P.3
Neubert, T.A.4
Ron, D.5
-
126
-
-
71749117953
-
AAA proteases in mitochondria: diverse functions of membrane-bound proteolytic machines
-
Tatsuta T., Langer T. AAA proteases in mitochondria: diverse functions of membrane-bound proteolytic machines. Res. Microbiol. 2009, 160:711-717.
-
(2009)
Res. Microbiol.
, vol.160
, pp. 711-717
-
-
Tatsuta, T.1
Langer, T.2
-
127
-
-
0039048984
-
Afg3p, a mitochondrial ATP-dependent metalloprotease, is involved in degradation of mitochondrially-encoded Cox1, Cox3, Cob, Su6, Su8 and Su9 subunits of the inner membrane complexes III, IV and V
-
Guélin E., Rep M., Grivell L.A. Afg3p, a mitochondrial ATP-dependent metalloprotease, is involved in degradation of mitochondrially-encoded Cox1, Cox3, Cob, Su6, Su8 and Su9 subunits of the inner membrane complexes III, IV and V. FEBS Lett. 1996, 381:42-46.
-
(1996)
FEBS Lett.
, vol.381
, pp. 42-46
-
-
Guélin, E.1
Rep, M.2
Grivell, L.A.3
-
128
-
-
0030008581
-
The YTA10-12 complex, an AAA protease with chaperone-like activity in the inner membrane of mitochondria
-
Arlt H., Tauer R., Feldmann H., Neupert W., Langer T. The YTA10-12 complex, an AAA protease with chaperone-like activity in the inner membrane of mitochondria. Cell 1996, 85:875-885.
-
(1996)
Cell
, vol.85
, pp. 875-885
-
-
Arlt, H.1
Tauer, R.2
Feldmann, H.3
Neupert, W.4
Langer, T.5
-
129
-
-
0029775087
-
AAA proteases with catalytic sites on opposite membrane surfaces comprise a proteolytic system for the ATP-dependent degradation of inner membrane proteins in mitochondria
-
Leonhard K., Herrmann J.M., Stuart R.A., Mannhaupt G., Neupert W., Langer T. AAA proteases with catalytic sites on opposite membrane surfaces comprise a proteolytic system for the ATP-dependent degradation of inner membrane proteins in mitochondria. EMBO J. 1996, 15:4218-4229.
-
(1996)
EMBO J.
, vol.15
, pp. 4218-4229
-
-
Leonhard, K.1
Herrmann, J.M.2
Stuart, R.A.3
Mannhaupt, G.4
Neupert, W.5
Langer, T.6
-
130
-
-
0032541406
-
The formation of respiratory chain complexes in mitochondria is under the proteolytic control of the m-AAA protease
-
Arlt H., Steglich G., Perryman R., Guiard B., Neupert W., Langer T. The formation of respiratory chain complexes in mitochondria is under the proteolytic control of the m-AAA protease. EMBO J. 1998, 17:4837-4847.
-
(1998)
EMBO J.
, vol.17
, pp. 4837-4847
-
-
Arlt, H.1
Steglich, G.2
Perryman, R.3
Guiard, B.4
Neupert, W.5
Langer, T.6
-
131
-
-
13244298414
-
Characterization of peptides released from mitochondria: evidence for constant proteolysis and peptide efflux
-
Augustin S., Nolden M., Müller S., Hardt O., Arnold I., Langer T. Characterization of peptides released from mitochondria: evidence for constant proteolysis and peptide efflux. J. Biol. Chem. 2005, 280:2691-2699.
-
(2005)
J. Biol. Chem.
, vol.280
, pp. 2691-2699
-
-
Augustin, S.1
Nolden, M.2
Müller, S.3
Hardt, O.4
Arnold, I.5
Langer, T.6
-
132
-
-
0033602381
-
Chaperone-like activity of the AAA domain of the yeast Yme1 AAA protease
-
Leonhard K., Stiegler A., Neupert W., Langer T. Chaperone-like activity of the AAA domain of the yeast Yme1 AAA protease. Nature 1999, 398:348-351.
-
(1999)
Nature
, vol.398
, pp. 348-351
-
-
Leonhard, K.1
Stiegler, A.2
Neupert, W.3
Langer, T.4
-
133
-
-
26844484821
-
The m-AAA protease defective in hereditary spastic paraplegia controls ribosome assembly in mitochondria
-
Nolden M., Ehses S., Koppen M., Bernacchia A., Rugarli E.I., Langer T. The m-AAA protease defective in hereditary spastic paraplegia controls ribosome assembly in mitochondria. Cell 2005, 123:277-289.
-
(2005)
Cell
, vol.123
, pp. 277-289
-
-
Nolden, M.1
Ehses, S.2
Koppen, M.3
Bernacchia, A.4
Rugarli, E.I.5
Langer, T.6
-
134
-
-
33750986200
-
A new function in translocation for the mitochondrial i-AAA protease Yme1: import of polynucleotide phosphorylase into the intermembrane space
-
Rainey R.N., Glavin J.D., Chen H.W., French S.W., Teitell M.A., Koehler C.M. A new function in translocation for the mitochondrial i-AAA protease Yme1: import of polynucleotide phosphorylase into the intermembrane space. Mol. Cell. Biol. 2006, 26:8488-8497.
-
(2006)
Mol. Cell. Biol.
, vol.26
, pp. 8488-8497
-
-
Rainey, R.N.1
Glavin, J.D.2
Chen, H.W.3
French, S.W.4
Teitell, M.A.5
Koehler, C.M.6
-
135
-
-
0344736798
-
Loss of m-AAA protease in mitochondria causes complex I deficiency and increased sensitivity to oxidative stress in hereditary spastic paraplegia
-
Atorino L., Silvestri L., Koppen M., Cassina L., Ballabio A., Marconi R., Langer T., Casari G. Loss of m-AAA protease in mitochondria causes complex I deficiency and increased sensitivity to oxidative stress in hereditary spastic paraplegia. J. Cell Biol. 2003, 163:777-787.
-
(2003)
J. Cell Biol.
, vol.163
, pp. 777-787
-
-
Atorino, L.1
Silvestri, L.2
Koppen, M.3
Cassina, L.4
Ballabio, A.5
Marconi, R.6
Langer, T.7
Casari, G.8
-
136
-
-
0028954475
-
Identification of a protein with homology to hsp90 that binds the type 1 tumor necrosis factor receptor
-
Song H.Y., Dunbar J.D., Zhang Y.X., Guo D., Donner D.B. Identification of a protein with homology to hsp90 that binds the type 1 tumor necrosis factor receptor. J. Biol. Chem. 1995, 270:3574-3581.
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 3574-3581
-
-
Song, H.Y.1
Dunbar, J.D.2
Zhang, Y.X.3
Guo, D.4
Donner, D.B.5
-
137
-
-
0029760873
-
A new member of the hsp90 family of molecular chaperones interacts with the retinoblastoma protein during mitosis and after heat shock
-
Chen C.F., Chen Y., Dai K., Chen P.L., Riley D.J., Lee W.H. A new member of the hsp90 family of molecular chaperones interacts with the retinoblastoma protein during mitosis and after heat shock. Mol. Cell. Biol. 1996, 16:4691-4699.
-
(1996)
Mol. Cell. Biol.
, vol.16
, pp. 4691-4699
-
-
Chen, C.F.1
Chen, Y.2
Dai, K.3
Chen, P.L.4
Riley, D.J.5
Lee, W.H.6
-
138
-
-
0034603178
-
The hsp90-related protein TRAP1 is a mitochondrial protein with distinct functional properties
-
Felts S.J., Owen B.A., Nguyen P., Trepel J., Donner D.B., Toft D.O. The hsp90-related protein TRAP1 is a mitochondrial protein with distinct functional properties. J. Biol. Chem. 2000, 275:3305-3312.
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 3305-3312
-
-
Felts, S.J.1
Owen, B.A.2
Nguyen, P.3
Trepel, J.4
Donner, D.B.5
Toft, D.O.6
-
139
-
-
0034633963
-
Immunoelectron microscopy provides evidence that tumor necrosis factor receptor-associated protein 1 (TRAP-1) is a mitochondrial protein which also localizes at specific extramitochondrial sites
-
Cechetto J.D., Gupta R.S. Immunoelectron microscopy provides evidence that tumor necrosis factor receptor-associated protein 1 (TRAP-1) is a mitochondrial protein which also localizes at specific extramitochondrial sites. Exp. Cell Res. 2000, 260:30-39.
-
(2000)
Exp. Cell Res.
, vol.260
, pp. 30-39
-
-
Cechetto, J.D.1
Gupta, R.S.2
-
140
-
-
28644443855
-
The HSP90 family of genes in the human genome: insights into their divergence and evolution
-
Chen B., Piel W.H., Gui L., Bruford E., Monteiro A. The HSP90 family of genes in the human genome: insights into their divergence and evolution. Genomics 2005, 86:627-637.
-
(2005)
Genomics
, vol.86
, pp. 627-637
-
-
Chen, B.1
Piel, W.H.2
Gui, L.3
Bruford, E.4
Monteiro, A.5
-
141
-
-
45549104450
-
The ATPase cycle of the mitochondrial Hsp90 analog Trap1
-
Leskovar A., Wegele H., Werbeck N.D., Buchner J., Reinstein J. The ATPase cycle of the mitochondrial Hsp90 analog Trap1. J. Biol. Chem. 2008, 283:11677-11688.
-
(2008)
J. Biol. Chem.
, vol.283
, pp. 11677-11688
-
-
Leskovar, A.1
Wegele, H.2
Werbeck, N.D.3
Buchner, J.4
Reinstein, J.5
-
142
-
-
5644259582
-
Involvement of tumor necrosis factor receptor-associated protein 1 (TRAP1) in apoptosis induced by beta-hydroxyisovalerylshikonin
-
Masuda Y., Shima G., Aiuchi T., Horie M., Hori K., Nakajo S., Kajimoto S., Shibayama-Imazu T., Nakaya K. Involvement of tumor necrosis factor receptor-associated protein 1 (TRAP1) in apoptosis induced by beta-hydroxyisovalerylshikonin. J. Biol. Chem. 2004, 279:42503-42515.
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 42503-42515
-
-
Masuda, Y.1
Shima, G.2
Aiuchi, T.3
Horie, M.4
Hori, K.5
Nakajo, S.6
Kajimoto, S.7
Shibayama-Imazu, T.8
Nakaya, K.9
-
143
-
-
34547138950
-
Heat shock protein 75 (TRAP1) antagonizes reactive oxygen species generation and protects cells from granzyme M-mediated apoptosis
-
Hua G., Zhang Q., Fan Z. Heat shock protein 75 (TRAP1) antagonizes reactive oxygen species generation and protects cells from granzyme M-mediated apoptosis. J. Biol. Chem. 2007, 282:20553-20560.
-
(2007)
J. Biol. Chem.
, vol.282
, pp. 20553-20560
-
-
Hua, G.1
Zhang, Q.2
Fan, Z.3
-
144
-
-
33846426804
-
Iron chelation study in a normal human hepatocyte cell line suggests that tumor necrosis factor receptor-associated protein 1 (TRAP1) regulates production of reactive oxygen species
-
Im C.N., Lee J.S., Zheng Y., Seo J.S. Iron chelation study in a normal human hepatocyte cell line suggests that tumor necrosis factor receptor-associated protein 1 (TRAP1) regulates production of reactive oxygen species. J. Cell. Biochem. 2007, 100:474-486.
-
(2007)
J. Cell. Biochem.
, vol.100
, pp. 474-486
-
-
Im, C.N.1
Lee, J.S.2
Zheng, Y.3
Seo, J.S.4
-
145
-
-
36248980938
-
Tumor necrosis factor-associated protein 1 (TRAP-1) protects cells from oxidative stress and apoptosis
-
Montesano Gesualdi N., Chirico G., Pirozzi G., Costantino E., Landriscina M., Esposito F. Tumor necrosis factor-associated protein 1 (TRAP-1) protects cells from oxidative stress and apoptosis. Stress 2007, 10:342-350.
-
(2007)
Stress
, vol.10
, pp. 342-350
-
-
Montesano Gesualdi, N.1
Chirico, G.2
Pirozzi, G.3
Costantino, E.4
Landriscina, M.5
Esposito, F.6
-
146
-
-
35348887850
-
Regulation of tumor cell mitochondrial homeostasis by an organelle-specific Hsp90 chaperone network
-
Kang B.H., Plescia J., Dohi T., Rosa J., Doxsey S.J., Altieri D.C. Regulation of tumor cell mitochondrial homeostasis by an organelle-specific Hsp90 chaperone network. Cell 2007, 131:257-270.
-
(2007)
Cell
, vol.131
, pp. 257-270
-
-
Kang, B.H.1
Plescia, J.2
Dohi, T.3
Rosa, J.4
Doxsey, S.J.5
Altieri, D.C.6
-
147
-
-
34547127902
-
PINK1 protects against oxidative stress by phosphorylating mitochondrial chaperone TRAP1
-
Pridgeon J.W., Olzmann J.A., Chin L.-S., Li L. PINK1 protects against oxidative stress by phosphorylating mitochondrial chaperone TRAP1. PLoS Biol. 2007, 5:1494-1503.
-
(2007)
PLoS Biol.
, vol.5
, pp. 1494-1503
-
-
Pridgeon, J.W.1
Olzmann, J.A.2
Chin, L.-S.3
Li, L.4
-
148
-
-
79952451427
-
Mitophagy: the latest problem for Parkinson's disease
-
Vives-Bauza C., Przedborski S. Mitophagy: the latest problem for Parkinson's disease. Trends Mol. Med. 2011, 17:158-165.
-
(2011)
Trends Mol. Med.
, vol.17
, pp. 158-165
-
-
Vives-Bauza, C.1
Przedborski, S.2
-
149
-
-
50149121528
-
The kinase domain of mitochondrial PINK1 faces the cytoplasm
-
Zhou C., Huang Y., Shao Y., May J., Prou D., Perier C., Dauer W., Schon E.A., Przedborski S. The kinase domain of mitochondrial PINK1 faces the cytoplasm. Proc. Natl. Acad. Sci. U. S. A. 2008, 105:12022-12027.
-
(2008)
Proc. Natl. Acad. Sci. U. S. A.
, vol.105
, pp. 12022-12027
-
-
Zhou, C.1
Huang, Y.2
Shao, Y.3
May, J.4
Prou, D.5
Perier, C.6
Dauer, W.7
Schon, E.A.8
Przedborski, S.9
-
150
-
-
79951967246
-
HTRA proteases: regulated proteolysis in protein quality control
-
Clausen T., Kaiser M., Huber R., Ehrmann M. HTRA proteases: regulated proteolysis in protein quality control. Nat. Rev. Mol. Cell Biol. 2011, 12:152-162.
-
(2011)
Nat. Rev. Mol. Cell Biol.
, vol.12
, pp. 152-162
-
-
Clausen, T.1
Kaiser, M.2
Huber, R.3
Ehrmann, M.4
-
151
-
-
25444491980
-
Structure and function of HtrA family proteins, the key players in protein quality control
-
Kim D.Y., Kim K.K. Structure and function of HtrA family proteins, the key players in protein quality control. J. Biochem. Mol. Biol. 2005, 38:266-274.
-
(2005)
J. Biochem. Mol. Biol.
, vol.38
, pp. 266-274
-
-
Kim, D.Y.1
Kim, K.K.2
-
152
-
-
0036752926
-
The HtrA family of proteases: implications for protein composition and cell fate
-
Clausen T., Southan C., Ehrmann M. The HtrA family of proteases: implications for protein composition and cell fate. Mol. Cell 2002, 10:443-455.
-
(2002)
Mol. Cell
, vol.10
, pp. 443-455
-
-
Clausen, T.1
Southan, C.2
Ehrmann, M.3
-
154
-
-
0033825336
-
Characterization of human HtrA2, a novel serine protease involved in the mammalian cellular stress response
-
Gray C.W., Ward R.V., Karran E., Turconi S., Rowles A., Viglienghi D., Southan C., Barton A., Fantom K.G., West A., Savopoulos J., Hassan N.J., Clinkenbeard H., Hanning C., Amegadzie B., Davis J.B., Dingwall C., Livi G.P., Creasy C.L. Characterization of human HtrA2, a novel serine protease involved in the mammalian cellular stress response. Eur. J. Biochem. 2000, 267:5699-5710.
-
(2000)
Eur. J. Biochem.
, vol.267
, pp. 5699-5710
-
-
Gray, C.W.1
Ward, R.V.2
Karran, E.3
Turconi, S.4
Rowles, A.5
Viglienghi, D.6
Southan, C.7
Barton, A.8
Fantom, K.G.9
West, A.10
Savopoulos, J.11
Hassan, N.J.12
Clinkenbeard, H.13
Hanning, C.14
Amegadzie, B.15
Davis, J.B.16
Dingwall, C.17
Livi, G.P.18
Creasy, C.L.19
-
155
-
-
0142246441
-
Loss of Omi mitochondrial protease activity causes the neuromuscular disorder of mnd2 mutant mice
-
Jones J.M., Datta P., Srinivasula S.M., Ji W., Gupta S., Zhang Z., Davies E., Hajnoczky G., Saunders T.L., Van Keuren M.L., Fernandes-Alnemri T., Meisler M.H., Alnemri E.S. Loss of Omi mitochondrial protease activity causes the neuromuscular disorder of mnd2 mutant mice. Nature 2003, 425:721-727.
-
(2003)
Nature
, vol.425
, pp. 721-727
-
-
Jones, J.M.1
Datta, P.2
Srinivasula, S.M.3
Ji, W.4
Gupta, S.5
Zhang, Z.6
Davies, E.7
Hajnoczky, G.8
Saunders, T.L.9
Van Keuren, M.L.10
Fernandes-Alnemri, T.11
Meisler, M.H.12
Alnemri, E.S.13
-
156
-
-
35748935851
-
The mitochondrial protease HtrA2 is regulated by Parkinson's disease-associated kinase PINK1
-
Plun-Favreau H., Klupsch K., Moisoi N., Gandhi S., Kjaer S., Frith D., Harvey K., Deas E., Harvey R.J., McDonald N., Wood N.W., Martins L.M., Downward J. The mitochondrial protease HtrA2 is regulated by Parkinson's disease-associated kinase PINK1. Nat. Cell Biol. 2007, 9:1243-1252.
-
(2007)
Nat. Cell Biol.
, vol.9
, pp. 1243-1252
-
-
Plun-Favreau, H.1
Klupsch, K.2
Moisoi, N.3
Gandhi, S.4
Kjaer, S.5
Frith, D.6
Harvey, K.7
Deas, E.8
Harvey, R.J.9
McDonald, N.10
Wood, N.W.11
Martins, L.M.12
Downward, J.13
|