PTEN-inducible kinase 1 (PINK1)/Park6 is indispensable for normal heart function

Proceedings of the National Academy of Sciences of the United States of America

Volumn 108, Issue 23, 2011, Pages 9572-9577

  Billia, Filio ^a,b   Hauck, Ludger ^a   Konecny, Filip ^c   Rao, Vivek ^b   Shen, Jie ^d   Mak, Tak Wah ^a  

^a Princess Margaret Hospital   (Canada)

^b UNIVERSITY HEALTH NETWORK   (Canada)

^c UNIVERSITY OF TORONTO   (Canada)

^d HARVARD MEDICAL SCHOOL   (United States)

Author keywords

Mitochondrial energetics; Mitochondrial swelling; Mitochonopathy

Indexed keywords

PROTEIN SERINE THREONINE KINASE; PTEN INDUCIBLE KINASE 1; UNCLASSIFIED DRUG;

ADULT; AGED; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; APOPTOSIS; ARTICLE; CAPILLARY DENSITY; CELL FUNCTION; CONTROLLED STUDY; DISORDERS OF MITOCHONDRIAL FUNCTIONS; ENZYME ACTIVITY; ENZYME LOCALIZATION; FEMALE; FIBROSIS; HEART FAILURE; HEART FUNCTION; HEART LEFT VENTRICLE FAILURE; HEART MUSCLE CELL; HEART VENTRICLE FUNCTION; HEART VENTRICLE HYPERTROPHY; HOMEOSTASIS; HUMAN; IN VIVO STUDY; MALE; MITOCHONDRION; MOUSE; NONHUMAN; OXIDATIVE STRESS; PHENOTYPE; PRIORITY JOURNAL; REGULATORY MECHANISM;

ADULT; ANIMALS; ANIMALS, NEWBORN; BLOTTING, WESTERN; CARDIOMEGALY; CELLS, CULTURED; FEMALE; HEART FAILURE; HUMANS; MALE; MEMBRANE POTENTIAL, MITOCHONDRIAL; MICE; MICE, KNOCKOUT; MICROSCOPY, FLUORESCENCE; MIDDLE AGED; MUTATION; MYOCARDIUM; MYOCYTES, CARDIAC; PROTEIN KINASES; RATS; RATS, WISTAR; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; TIME FACTORS; VENTRICULAR DYSFUNCTION, LEFT;

MUS;

EID: 79959344616     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1106291108     Document Type: Article

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