The protonophore CCCP interferes with lysosomal degradation of autophagic cargo in yeast and mammalian cells

Autophagy

Volumn 9, Issue 11, 2013, Pages 1862-1875

  Padman, Benjamin S ^a   Bach, Markus ^a   Lucarelli, Giuseppe ^a   Prescott, Mark ^a   Ramm, Georg ^a  

^a MONASH UNIVERSITY   (Australia)

Author keywords

CCCP; DiOC6; Lysosomal chloride; Mitophagy; MitoTracker; PARK2; Parkin; TMRM

Indexed keywords

CARBONYL CYANIDE CHLOROPHENYLHYDRAZONE; PARKIN;

ACIDIFICATION; ARTICLE; AUTOPHAGOSOME; AUTOPHAGY; CELL FUNCTION; CYTOPLASM; ELECTRON MICROSCOPY; ENDOCYTOSIS; HELA CELL; LYSOSOME; MAMMAL CELL; MITOCHONDRIAL MEMBRANE POTENTIAL; MITOCHONDRION; MITOPHAGY; NONHUMAN; PH; PROTEIN EXPRESSION; YEAST CELL;

MAMMALIA;

CCCP; DIOC6; LYSOSOMAL CHLORIDE; MITOPHAGY; MITOTRACKER; PARK2; PARKIN; TMRM;

AUTOPHAGY; BIOLOGICAL TRANSPORT; CARBONYL CYANIDE M-CHLOROPHENYL HYDRAZONE; COLORING AGENTS; HEK293 CELLS; HELA CELLS; HUMANS; HYDROGEN-ION CONCENTRATION; INTRACELLULAR MEMBRANES; LYSOSOMES; MEMBRANE POTENTIALS; MEMBRANE TRANSPORT PROTEINS; MITOCHONDRIAL DEGRADATION; PHAGOSOMES; RECEPTORS, CELL SURFACE; SACCHAROMYCES CEREVISIAE; UBIQUITIN-PROTEIN LIGASES; VACUOLES;

EID: 84887466109     PISSN: 15548627     EISSN: 15548635     Source Type: Journal    
DOI: 10.4161/auto.26557     Document Type: Article

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