-
1
-
-
33748560432
-
Ghrelin modulates the activity and synaptic input organization of midbrain dopamine neurons while promoting appetite
-
A. Abizaid, Z.W. Liu, Z.B. Andrews, M. Shanabrough, E. Borok, J.D. Elsworth, R.H. Roth, M.W. Sleeman, M.R. Picciotto, M.H. Tschöp, and et al. Ghrelin modulates the activity and synaptic input organization of midbrain dopamine neurons while promoting appetite J. Clin. Invest. 116 2006 3229 3239
-
(2006)
J. Clin. Invest.
, vol.116
, pp. 3229-3239
-
-
Abizaid, A.1
Liu, Z.W.2
Andrews, Z.B.3
Shanabrough, M.4
Borok, E.5
Elsworth, J.D.6
Roth, R.H.7
Sleeman, M.W.8
Picciotto, M.R.9
Tschöp, M.H.10
-
2
-
-
84863664040
-
Perinuclear mitochondrial clustering creates an oxidant-rich nuclear domain required for hypoxia-induced transcription
-
A.B. Al-Mehdi, V.M. Pastukh, B.M. Swiger, D.J. Reed, M.R. Patel, G.C. Bardwell, V.V. Pastukh, M.F. Alexeyev, and M.N. Gillespie Perinuclear mitochondrial clustering creates an oxidant-rich nuclear domain required for hypoxia-induced transcription Sci. Signal. 5 2012 ra47
-
(2012)
Sci. Signal.
, vol.5
, pp. ra47
-
-
Al-Mehdi, A.B.1
Pastukh, V.M.2
Swiger, B.M.3
Reed, D.J.4
Patel, M.R.5
Bardwell, G.C.6
Pastukh, V.V.7
Alexeyev, M.F.8
Gillespie, M.N.9
-
3
-
-
70449673061
-
Ghrelin promotes and protects nigrostriatal dopamine function via a UCP2-dependent mitochondrial mechanism
-
Z.B. Andrews, D. Erion, R. Beiler, Z.W. Liu, A. Abizaid, J. Zigman, J.D. Elsworth, J.M. Savitt, R. DiMarchi, M. Tschoep, and et al. Ghrelin promotes and protects nigrostriatal dopamine function via a UCP2-dependent mitochondrial mechanism J. Neurosci. 29 2009 14057 14065
-
(2009)
J. Neurosci.
, vol.29
, pp. 14057-14065
-
-
Andrews, Z.B.1
Erion, D.2
Beiler, R.3
Liu, Z.W.4
Abizaid, A.5
Zigman, J.6
Elsworth, J.D.7
Savitt, J.M.8
DiMarchi, R.9
Tschoep, M.10
-
4
-
-
12144284373
-
Uncoupling protein-2 is critical for nigral dopamine cell survival in a mouse model of Parkinson's disease
-
Z.B. Andrews, B. Horvath, C.J. Barnstable, J. Elsworth, L. Yang, M.F. Beal, R.H. Roth, R.T. Matthews, and T.L. Horvath Uncoupling protein-2 is critical for nigral dopamine cell survival in a mouse model of Parkinson's disease J. Neurosci. 25 2005 184 191
-
(2005)
J. Neurosci.
, vol.25
, pp. 184-191
-
-
Andrews, Z.B.1
Horvath, B.2
Barnstable, C.J.3
Elsworth, J.4
Yang, L.5
Beal, M.F.6
Roth, R.H.7
Matthews, R.T.8
Horvath, T.L.9
-
6
-
-
49649122302
-
UCP2 mediates ghrelin's action on NPY/AgRP neurons by lowering free radicals
-
Z.B. Andrews, Z.W. Liu, N. Walllingford, D.M. Erion, E. Borok, J.M. Friedman, M.H. Tschöp, M. Shanabrough, G. Cline, G.I. Shulman, and et al. UCP2 mediates ghrelin's action on NPY/AgRP neurons by lowering free radicals Nature 454 2008 846 851
-
(2008)
Nature
, vol.454
, pp. 846-851
-
-
Andrews, Z.B.1
Liu, Z.W.2
Walllingford, N.3
Erion, D.M.4
Borok, E.5
Friedman, J.M.6
Tschöp, M.H.7
Shanabrough, M.8
Cline, G.9
Shulman, G.I.10
-
7
-
-
33745895656
-
Uncoupling protein-2 promotes nigrostriatal dopamine neuronal function
-
Z.B. Andrews, A. Rivera, J.D. Elsworth, R.H. Roth, L. Agnati, B. Gago, A. Abizaid, M. Schwartz, K. Fuxe, and T.L. Horvath Uncoupling protein-2 promotes nigrostriatal dopamine neuronal function Eur. J. Neurosci. 24 2006 32 36
-
(2006)
Eur. J. Neurosci.
, vol.24
, pp. 32-36
-
-
Andrews, Z.B.1
Rivera, A.2
Elsworth, J.D.3
Roth, R.H.4
Agnati, L.5
Gago, B.6
Abizaid, A.7
Schwartz, M.8
Fuxe, K.9
Horvath, T.L.10
-
8
-
-
0033667705
-
Disruption of the uncoupling protein-2 gene in mice reveals a role in immunity and reactive oxygen species production
-
D. Arsenijevic, H. Onuma, C. Pecqueur, S. Raimbault, B.S. Manning, B. Miroux, E. Couplan, M.C. Alves-Guerra, M. Goubern, R. Surwit, and et al. Disruption of the uncoupling protein-2 gene in mice reveals a role in immunity and reactive oxygen species production Nat. Genet. 26 2000 435 439
-
(2000)
Nat. Genet.
, vol.26
, pp. 435-439
-
-
Arsenijevic, D.1
Onuma, H.2
Pecqueur, C.3
Raimbault, S.4
Manning, B.S.5
Miroux, B.6
Couplan, E.7
Alves-Guerra, M.C.8
Goubern, M.9
Surwit, R.10
-
9
-
-
0141482021
-
Activation of ATP-sensitive K+ (K(ATP)) channels by H2O2 underlies glutamate-dependent inhibition of striatal dopamine release
-
M.V. Avshalumov, and M.E. Rice Activation of ATP-sensitive K+ (K(ATP)) channels by H2O2 underlies glutamate-dependent inhibition of striatal dopamine release Proc. Natl. Acad. Sci. USA 100 2003 11729 11734
-
(2003)
Proc. Natl. Acad. Sci. USA
, vol.100
, pp. 11729-11734
-
-
Avshalumov, M.V.1
Rice, M.E.2
-
10
-
-
58249110569
-
Positive and negative regulation of insulin signaling by reactive oxygen and nitrogen species
-
N. Bashan, J. Kovsan, I. Kachko, H. Ovadia, and A. Rudich Positive and negative regulation of insulin signaling by reactive oxygen and nitrogen species Physiol. Rev. 89 2009 27 71
-
(2009)
Physiol. Rev.
, vol.89
, pp. 27-71
-
-
Bashan, N.1
Kovsan, J.2
Kachko, I.3
Ovadia, H.4
Rudich, A.5
-
11
-
-
0036683694
-
Brain mitochondrial uncoupling protein 2 (UCP2): A protective stress signal in neuronal injury
-
I. Bechmann, S. Diano, C.H. Warden, T. Bartfai, R. Nitsch, and T.L. Horvath Brain mitochondrial uncoupling protein 2 (UCP2): A protective stress signal in neuronal injury Biochem. Pharmacol. 64 2002 363 367
-
(2002)
Biochem. Pharmacol.
, vol.64
, pp. 363-367
-
-
Bechmann, I.1
Diano, S.2
Warden, C.H.3
Bartfai, T.4
Nitsch, R.5
Horvath, T.L.6
-
12
-
-
33847065926
-
Role for mitochondrial reactive oxygen species in brain lipid sensing: Redox regulation of food intake
-
A. Benani, S. Troy, M.C. Carmona, X. Fioramonti, A. Lorsignol, C. Leloup, L. Casteilla, and L. Pénicaud Role for mitochondrial reactive oxygen species in brain lipid sensing: redox regulation of food intake Diabetes 56 2007 152 160
-
(2007)
Diabetes
, vol.56
, pp. 152-160
-
-
Benani, A.1
Troy, S.2
Carmona, M.C.3
Fioramonti, X.4
Lorsignol, A.5
Leloup, C.6
Casteilla, L.7
Pénicaud, L.8
-
13
-
-
33947574775
-
Reduced TOR signaling extends chronological life span via increased respiration and upregulation of mitochondrial gene expression
-
N.D. Bonawitz, M. Chatenay-Lapointe, Y. Pan, and G.S. Shadel Reduced TOR signaling extends chronological life span via increased respiration and upregulation of mitochondrial gene expression Cell Metab. 5 2007 265 277
-
(2007)
Cell Metab.
, vol.5
, pp. 265-277
-
-
Bonawitz, N.D.1
Chatenay-Lapointe, M.2
Pan, Y.3
Shadel, G.S.4
-
14
-
-
25144476923
-
Physiological functions of the mitochondrial uncoupling proteins UCP2 and UCP3
-
M.D. Brand, and T.C. Esteves Physiological functions of the mitochondrial uncoupling proteins UCP2 and UCP3 Cell Metab. 2 2005 85 93
-
(2005)
Cell Metab.
, vol.2
, pp. 85-93
-
-
Brand, M.D.1
Esteves, T.C.2
-
15
-
-
70349976007
-
The TOM complex is involved in the release of superoxide anion from mitochondria
-
M. Budzińska, H. Gałgańska, A. Karachitos, M. Wojtkowska, and H. Kmita The TOM complex is involved in the release of superoxide anion from mitochondria J. Bioenerg. Biomembr. 41 2009 361 367
-
(2009)
J. Bioenerg. Biomembr.
, vol.41
, pp. 361-367
-
-
Budzińska, M.1
Gałgańska, H.2
Karachitos, A.3
Wojtkowska, M.4
Kmita, H.5
-
16
-
-
1842665662
-
Mitochondrial signaling: The retrograde response
-
R.A. Butow, and N.G. Avadhani Mitochondrial signaling: The retrograde response Mol. Cell 14 2004 1 15
-
(2004)
Mol. Cell
, vol.14
, pp. 1-15
-
-
Butow, R.A.1
Avadhani, N.G.2
-
19
-
-
84901410479
-
Mitochondria as signaling organelles
-
N.S. Chandel Mitochondria as signaling organelles BMC Biol. 12 2014 34
-
(2014)
BMC Biol.
, vol.12
, pp. 34
-
-
Chandel, N.S.1
-
20
-
-
20244377700
-
Uncoupling protein 2 protects dopaminergic neurons from acute 1,2,3,6-methyl-phenyl-tetrahydropyridine toxicity
-
B. Conti, S. Sugama, J. Lucero, R. Winsky-Sommerer, S.A. Wirz, P. Maher, Z. Andrews, A.M. Barr, M.C. Morale, C. Paneda, and et al. Uncoupling protein 2 protects dopaminergic neurons from acute 1,2,3,6-methyl-phenyl-tetrahydropyridine toxicity J. Neurochem. 93 2005 493 501
-
(2005)
J. Neurochem.
, vol.93
, pp. 493-501
-
-
Conti, B.1
Sugama, S.2
Lucero, J.3
Winsky-Sommerer, R.4
Wirz, S.A.5
Maher, P.6
Andrews, Z.7
Barr, A.M.8
Morale, M.C.9
Paneda, C.10
-
21
-
-
33845582594
-
A central thermogenic-like mechanism in feeding regulation: An interplay between arcuate nucleus T3 and UCP2
-
A. Coppola, Z.W. Liu, Z.B. Andrews, E. Paradis, M.C. Roy, J.M. Friedman, D. Ricquier, D. Richard, T.L. Horvath, X.B. Gao, and S. Diano A central thermogenic-like mechanism in feeding regulation: An interplay between arcuate nucleus T3 and UCP2 Cell Metab. 5 2007 21 33
-
(2007)
Cell Metab.
, vol.5
, pp. 21-33
-
-
Coppola, A.1
Liu, Z.W.2
Andrews, Z.B.3
Paradis, E.4
Roy, M.C.5
Friedman, J.M.6
Ricquier, D.7
Richard, D.8
Horvath, T.L.9
Gao, X.B.10
Diano, S.11
-
22
-
-
0037456519
-
The distribution and mechanism of action of ghrelin in the CNS demonstrates a novel hypothalamic circuit regulating energy homeostasis
-
M.A. Cowley, R.G. Smith, S. Diano, M. Tschöp, N. Pronchuk, K.L. Grove, C.J. Strasburger, M. Bidlingmaier, M. Esterman, M.L. Heiman, and et al. The distribution and mechanism of action of ghrelin in the CNS demonstrates a novel hypothalamic circuit regulating energy homeostasis Neuron 37 2003 649 661
-
(2003)
Neuron
, vol.37
, pp. 649-661
-
-
Cowley, M.A.1
Smith, R.G.2
Diano, S.3
Tschöp, M.4
Pronchuk, N.5
Grove, K.L.6
Strasburger, C.J.7
Bidlingmaier, M.8
Esterman, M.9
Heiman, M.L.10
-
23
-
-
84901849008
-
Effects of the mitochondrial respiratory chain on longevity in C. Elegans
-
B.M. Dancy, M.M. Sedensky, and P.G. Morgan Effects of the mitochondrial respiratory chain on longevity in C. elegans Exp. Gerontol. 56 2014 245 255
-
(2014)
Exp. Gerontol.
, vol.56
, pp. 245-255
-
-
Dancy, B.M.1
Sedensky, M.M.2
Morgan, P.G.3
-
24
-
-
44349154324
-
Overexpression of UCP2 protects thalamic neurons following global ischemia in the mouse
-
T. Deierborg, T. Wieloch, S. Diano, C.H. Warden, T.L. Horvath, and G. Mattiasson Overexpression of UCP2 protects thalamic neurons following global ischemia in the mouse Journal of cerebral blood flow and metabolism: official journal of the International Society of Cerebral Blood Flow and Metabolism 28 2008 1186 1195
-
(2008)
Journal of Cerebral Blood Flow and Metabolism: Official Journal of the International Society of Cerebral Blood Flow and Metabolism
, vol.28
, pp. 1186-1195
-
-
Deierborg, T.1
Wieloch, T.2
Diano, S.3
Warden, C.H.4
Horvath, T.L.5
Mattiasson, G.6
-
25
-
-
84855584488
-
Mitochondrial uncoupling protein 2 (UCP2) in glucose and lipid metabolism
-
S. Diano, and T.L. Horvath Mitochondrial uncoupling protein 2 (UCP2) in glucose and lipid metabolism Trends Mol. Med. 18 2012 52 58
-
(2012)
Trends Mol. Med.
, vol.18
, pp. 52-58
-
-
Diano, S.1
Horvath, T.L.2
-
26
-
-
0033696297
-
Mitochondrial uncoupling protein 2 (UCP2) in the nonhuman primate brain and pituitary
-
S. Diano, H.F. Urbanski, B. Horvath, I. Bechmann, A. Kagiya, G. Nemeth, F. Naftolin, C.H. Warden, and T.L. Horvath Mitochondrial uncoupling protein 2 (UCP2) in the nonhuman primate brain and pituitary Endocrinology 141 2000 4226 4238
-
(2000)
Endocrinology
, vol.141
, pp. 4226-4238
-
-
Diano, S.1
Urbanski, H.F.2
Horvath, B.3
Bechmann, I.4
Kagiya, A.5
Nemeth, G.6
Naftolin, F.7
Warden, C.H.8
Horvath, T.L.9
-
27
-
-
0242468451
-
Uncoupling protein 2 prevents neuronal death including that occurring during seizures: A mechanism for preconditioning
-
S. Diano, R.T. Matthews, P. Patrylo, L. Yang, M.F. Beal, C.J. Barnstable, and T.L. Horvath Uncoupling protein 2 prevents neuronal death including that occurring during seizures: A mechanism for preconditioning Endocrinology 144 2003 5014 5021
-
(2003)
Endocrinology
, vol.144
, pp. 5014-5021
-
-
Diano, S.1
Matthews, R.T.2
Patrylo, P.3
Yang, L.4
Beal, M.F.5
Barnstable, C.J.6
Horvath, T.L.7
-
28
-
-
33344479006
-
Ghrelin controls hippocampal spine synapse density and memory performance
-
S. Diano, S.A. Farr, S.C. Benoit, E.C. McNay, I. da Silva, B. Horvath, F.S. Gaskin, N. Nonaka, L.B. Jaeger, W.A. Banks, and et al. Ghrelin controls hippocampal spine synapse density and memory performance Nat. Neurosci. 9 2006 381 388
-
(2006)
Nat. Neurosci.
, vol.9
, pp. 381-388
-
-
Diano, S.1
Farr, S.A.2
Benoit, S.C.3
McNay, E.C.4
Da Silva, I.5
Horvath, B.6
Gaskin, F.S.7
Nonaka, N.8
Jaeger, L.B.9
Banks, W.A.10
-
29
-
-
80052496920
-
Peroxisome proliferation-associated control of reactive oxygen species sets melanocortin tone and feeding in diet-induced obesity
-
S. Diano, Z.W. Liu, J.K. Jeong, M.O. Dietrich, H.B. Ruan, E. Kim, S. Suyama, K. Kelly, E. Gyengesi, J.L. Arbiser, and et al. Peroxisome proliferation-associated control of reactive oxygen species sets melanocortin tone and feeding in diet-induced obesity Nat. Med. 17 2011 1121 1127
-
(2011)
Nat. Med.
, vol.17
, pp. 1121-1127
-
-
Diano, S.1
Liu, Z.W.2
Jeong, J.K.3
Dietrich, M.O.4
Ruan, H.B.5
Kim, E.6
Suyama, S.7
Kelly, K.8
Gyengesi, E.9
Arbiser, J.L.10
-
30
-
-
54849438798
-
Exercise-induced synaptogenesis in the hippocampus is dependent on UCP2-regulated mitochondrial adaptation
-
M.O. Dietrich, Z.B. Andrews, and T.L. Horvath Exercise-induced synaptogenesis in the hippocampus is dependent on UCP2-regulated mitochondrial adaptation J. Neurosci. 28 2008 10766 10771
-
(2008)
J. Neurosci.
, vol.28
, pp. 10766-10771
-
-
Dietrich, M.O.1
Andrews, Z.B.2
Horvath, T.L.3
-
31
-
-
84866108680
-
Limitations in anti-obesity drug development: The critical role of hunger-promoting neurons
-
M.O. Dietrich, and T.L. Horvath Limitations in anti-obesity drug development: The critical role of hunger-promoting neurons Nat. Rev. Drug Discov. 11 2012 675 691
-
(2012)
Nat. Rev. Drug Discov.
, vol.11
, pp. 675-691
-
-
Dietrich, M.O.1
Horvath, T.L.2
-
32
-
-
84884877043
-
Mitochondrial dynamics controlled by mitofusins regulate Agrp neuronal activity and diet-induced obesity
-
M.O. Dietrich, Z.W. Liu, and T.L. Horvath Mitochondrial dynamics controlled by mitofusins regulate Agrp neuronal activity and diet-induced obesity Cell 155 2013 188 199
-
(2013)
Cell
, vol.155
, pp. 188-199
-
-
Dietrich, M.O.1
Liu, Z.W.2
Horvath, T.L.3
-
33
-
-
84925538202
-
Hypothalamic Agrp neurons drive stereotypic behaviors beyond feeding
-
M.O. Dietrich, M.R. Zimmer, J. Bober, and T.L. Horvath Hypothalamic Agrp neurons drive stereotypic behaviors beyond feeding Cell 160 2015 1222 1232
-
(2015)
Cell
, vol.160
, pp. 1222-1232
-
-
Dietrich, M.O.1
Zimmer, M.R.2
Bober, J.3
Horvath, T.L.4
-
34
-
-
78650944949
-
The cell-non-autonomous nature of electron transport chain-mediated longevity
-
J. Durieux, S. Wolff, and A. Dillin The cell-non-autonomous nature of electron transport chain-mediated longevity Cell 144 2011 79 91
-
(2011)
Cell
, vol.144
, pp. 79-91
-
-
Durieux, J.1
Wolff, S.2
Dillin, A.3
-
35
-
-
0037033039
-
Superoxide activates mitochondrial uncoupling protein 2 from the matrix side. Studies using targeted antioxidants
-
K.S. Echtay, M.P. Murphy, R.A. Smith, D.A. Talbot, and M.D. Brand Superoxide activates mitochondrial uncoupling protein 2 from the matrix side. Studies using targeted antioxidants J. Biol. Chem. 277 2002 47129 47135
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 47129-47135
-
-
Echtay, K.S.1
Murphy, M.P.2
Smith, R.A.3
Talbot, D.A.4
Brand, M.D.5
-
36
-
-
84901842374
-
Imaging dynamic redox processes with genetically encoded probes
-
D. Ezeriņa, B. Morgan, and T.P. Dick Imaging dynamic redox processes with genetically encoded probes J. Mol. Cell. Cardiol. 73 2014 43 49
-
(2014)
J. Mol. Cell. Cardiol.
, vol.73
, pp. 43-49
-
-
Ezeriņa, D.1
Morgan, B.2
Dick, T.P.3
-
37
-
-
84856821006
-
Signal transduction by mitochondrial oxidants
-
T. Finkel Signal transduction by mitochondrial oxidants J. Biol. Chem. 287 2012 4434 4440
-
(2012)
J. Biol. Chem.
, vol.287
, pp. 4434-4440
-
-
Finkel, T.1
-
38
-
-
0031019249
-
Uncoupling protein-2: A novel gene linked to obesity and hyperinsulinemia
-
C. Fleury, M. Neverova, S. Collins, S. Raimbault, O. Champigny, C. Levi-Meyrueis, F. Bouillaud, M.F. Seldin, R.S. Surwit, D. Ricquier, and C.H. Warden Uncoupling protein-2: A novel gene linked to obesity and hyperinsulinemia Nat. Genet. 15 1997 269 272
-
(1997)
Nat. Genet.
, vol.15
, pp. 269-272
-
-
Fleury, C.1
Neverova, M.2
Collins, S.3
Raimbault, S.4
Champigny, O.5
Levi-Meyrueis, C.6
Bouillaud, F.7
Seldin, M.F.8
Surwit, R.S.9
Ricquier, D.10
Warden, C.H.11
-
40
-
-
77956186783
-
Mitochondrial reactive oxygen species regulate cellular signaling and dictate biological outcomes
-
R.B. Hamanaka, and N.S. Chandel Mitochondrial reactive oxygen species regulate cellular signaling and dictate biological outcomes Trends Biochem. Sci. 35 2010 505 513
-
(2010)
Trends Biochem. Sci.
, vol.35
, pp. 505-513
-
-
Hamanaka, R.B.1
Chandel, N.S.2
-
41
-
-
84874229027
-
Mitochondrial reactive oxygen species promote epidermal differentiation and hair follicle development
-
R.B. Hamanaka, A. Glasauer, P. Hoover, S. Yang, H. Blatt, A.R. Mullen, S. Getsios, C.J. Gottardi, R.J. DeBerardinis, R.M. Lavker, and N.S. Chandel Mitochondrial reactive oxygen species promote epidermal differentiation and hair follicle development Sci. Signal. 6 2013 ra8
-
(2013)
Sci. Signal.
, vol.6
, pp. ra8
-
-
Hamanaka, R.B.1
Glasauer, A.2
Hoover, P.3
Yang, S.4
Blatt, H.5
Mullen, A.R.6
Getsios, S.7
Gottardi, C.J.8
DeBerardinis, R.J.9
Lavker, R.M.10
Chandel, N.S.11
-
42
-
-
0037458619
-
Voltage-dependent anion channels control the release of the superoxide anion from mitochondria to cytosol
-
D. Han, F. Antunes, R. Canali, D. Rettori, and E. Cadenas Voltage-dependent anion channels control the release of the superoxide anion from mitochondria to cytosol J. Biol. Chem. 278 2003 5557 5563
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 5557-5563
-
-
Han, D.1
Antunes, F.2
Canali, R.3
Rettori, D.4
Cadenas, E.5
-
43
-
-
84879602902
-
Evaluating and responding to mitochondrial dysfunction: The mitochondrial unfolded-protein response and beyond
-
C.M. Haynes, C.J. Fiorese, and Y.F. Lin Evaluating and responding to mitochondrial dysfunction: The mitochondrial unfolded-protein response and beyond Trends Cell Biol. 23 2013 311 318
-
(2013)
Trends Cell Biol.
, vol.23
, pp. 311-318
-
-
Haynes, C.M.1
Fiorese, C.J.2
Lin, Y.F.3
-
44
-
-
80053124673
-
Taking a "good" look at free radicals in the aging process
-
S. Hekimi, J. Lapointe, and Y. Wen Taking a "good" look at free radicals in the aging process Trends Cell Biol. 21 2011 569 576
-
(2011)
Trends Cell Biol.
, vol.21
, pp. 569-576
-
-
Hekimi, S.1
Lapointe, J.2
Wen, Y.3
-
46
-
-
0037397649
-
Uncoupling proteins-2 and 3 influence obesity and inflammation in transgenic mice
-
T.L. Horvath, S. Diano, S. Miyamoto, S. Barry, S. Gatti, D. Alberati, F. Livak, A. Lombardi, M. Moreno, F. Goglia, and et al. Uncoupling proteins-2 and 3 influence obesity and inflammation in transgenic mice International journal of obesity and related metabolic disorders: journal of the International Association for the Study of Obesity 27 2003 433 442
-
(2003)
International Journal of Obesity and Related Metabolic Disorders: Journal of the International Association for the Study of Obesity
, vol.27
, pp. 433-442
-
-
Horvath, T.L.1
Diano, S.2
Miyamoto, S.3
Barry, S.4
Gatti, S.5
Alberati, D.6
Livak, F.7
Lombardi, A.8
Moreno, M.9
Goglia, F.10
-
47
-
-
0033492873
-
Brain uncoupling protein 2: Uncoupled neuronal mitochondria predict thermal synapses in homeostatic centers
-
T.L. Horvath, C.H. Warden, M. Hajos, A. Lombardi, F. Goglia, and S. Diano Brain uncoupling protein 2: uncoupled neuronal mitochondria predict thermal synapses in homeostatic centers J. Neurosci. 19 1999 10417 10427
-
(1999)
J. Neurosci.
, vol.19
, pp. 10417-10427
-
-
Horvath, T.L.1
Warden, C.H.2
Hajos, M.3
Lombardi, A.4
Goglia, F.5
Diano, S.6
-
48
-
-
84908068704
-
Feedback regulation via AMPK and HIF-1 mediates ROS-dependent longevity in Caenorhabditis elegans
-
A.B. Hwang, E.A. Ryu, M. Artan, H.W. Chang, M.H. Kabir, H.J. Nam, D. Lee, J.S. Yang, S. Kim, W.B. Mair, and et al. Feedback regulation via AMPK and HIF-1 mediates ROS-dependent longevity in Caenorhabditis elegans Proc. Natl. Acad. Sci. USA 111 2014 E4458 E4467
-
(2014)
Proc. Natl. Acad. Sci. USA
, vol.111
, pp. E4458-E4467
-
-
Hwang, A.B.1
Ryu, E.A.2
Artan, M.3
Chang, H.W.4
Kabir, M.H.5
Nam, H.J.6
Lee, D.7
Yang, J.S.8
Kim, S.9
Mair, W.B.10
-
49
-
-
84859475062
-
Regulation of acid-base transporters by reactive oxygen species following mitochondrial fragmentation
-
D. Johnson, E. Allman, and K. Nehrke Regulation of acid-base transporters by reactive oxygen species following mitochondrial fragmentation Am. J. Physiol. Cell Physiol. 302 2012 C1045 C1054
-
(2012)
Am. J. Physiol. Cell Physiol.
, vol.302
, pp. C1045-C1054
-
-
Johnson, D.1
Allman, E.2
Nehrke, K.3
-
50
-
-
84655163961
-
Measuring reactive oxygen and nitrogen species with fluorescent probes: Challenges and limitations
-
B. Kalyanaraman, V. Darley-Usmar, K.J. Davies, P.A. Dennery, H.J. Forman, M.B. Grisham, G.E. Mann, K. Moore, L.J. Roberts 2nd, and H. Ischiropoulos Measuring reactive oxygen and nitrogen species with fluorescent probes: challenges and limitations Free Radic. Biol. Med. 52 2012 1 6
-
(2012)
Free Radic. Biol. Med.
, vol.52
, pp. 1-6
-
-
Kalyanaraman, B.1
Darley-Usmar, V.2
Davies, K.J.3
Dennery, P.A.4
Forman, H.J.5
Grisham, M.B.6
Mann, G.E.7
Moore, K.8
Roberts, L.J.9
Ischiropoulos, H.10
-
51
-
-
84924385915
-
Hypothalamic POMC neurons promote cannabinoid-induced feeding
-
M. Koch, L. Varela, J.G. Kim, J.D. Kim, F. Hernández-Nuño, S.E. Simonds, C.M. Castorena, C.R. Vianna, J.K. Elmquist, Y.M. Morozov, and et al. Hypothalamic POMC neurons promote cannabinoid-induced feeding Nature 519 2015 45 50
-
(2015)
Nature
, vol.519
, pp. 45-50
-
-
Koch, M.1
Varela, L.2
Kim, J.G.3
Kim, J.D.4
Hernández-Nuño, F.5
Simonds, S.E.6
Castorena, C.M.7
Vianna, C.R.8
Elmquist, J.K.9
Morozov, Y.M.10
-
52
-
-
0037039366
-
A significant portion of mitochondrial proton leak in intact thymocytes depends on expression of UCP2
-
S. Krauss, C.Y. Zhang, and B.B. Lowell A significant portion of mitochondrial proton leak in intact thymocytes depends on expression of UCP2 Proc. Natl. Acad. Sci. USA 99 2002 118 122
-
(2002)
Proc. Natl. Acad. Sci. USA
, vol.99
, pp. 118-122
-
-
Krauss, S.1
Zhang, C.Y.2
Lowell, B.B.3
-
54
-
-
78650177082
-
Inhibition of respiration extends C. Elegans life span via reactive oxygen species that increase HIF-1 activity
-
S.J. Lee, A.B. Hwang, and C. Kenyon Inhibition of respiration extends C. elegans life span via reactive oxygen species that increase HIF-1 activity Curr. Biol. 20 2010 2131 2136
-
(2010)
Curr. Biol.
, vol.20
, pp. 2131-2136
-
-
Lee, S.J.1
Hwang, A.B.2
Kenyon, C.3
-
55
-
-
33747039288
-
Mitochondrial reactive oxygen species are required for hypothalamic glucose sensing
-
C. Leloup, C. Magnan, A. Benani, E. Bonnet, T. Alquier, G. Offer, A. Carriere, A. Périquet, Y. Fernandez, A. Ktorza, and et al. Mitochondrial reactive oxygen species are required for hypothalamic glucose sensing Diabetes 55 2006 2084 2090
-
(2006)
Diabetes
, vol.55
, pp. 2084-2090
-
-
Leloup, C.1
Magnan, C.2
Benani, A.3
Bonnet, E.4
Alquier, T.5
Offer, G.6
Carriere, A.7
Périquet, A.8
Fernandez, Y.9
Ktorza, A.10
-
56
-
-
84890129552
-
Using exomarkers to assess mitochondrial reactive species in vivo
-
A. Logan, H.M. Cochemé, P.B. Li Pun, N. Apostolova, R.A. Smith, L. Larsen, D.S. Larsen, A.M. James, I.M. Fearnley, S. Rogatti, and et al. Using exomarkers to assess mitochondrial reactive species in vivo Biochim. Biophys. Acta 1840 2014 923 930
-
(2014)
Biochim. Biophys. Acta
, vol.1840
, pp. 923-930
-
-
Logan, A.1
Cochemé, H.M.2
Li Pun, P.B.3
Apostolova, N.4
Smith, R.A.5
Larsen, L.6
Larsen, D.S.7
James, A.M.8
Fearnley, I.M.9
Rogatti, S.10
-
57
-
-
84907016676
-
PPARγ ablation sensitizes proopiomelanocortin neurons to leptin during high-fat feeding
-
L. Long, C. Toda, J.K. Jeong, T.L. Horvath, and S. Diano PPARγ ablation sensitizes proopiomelanocortin neurons to leptin during high-fat feeding J. Clin. Invest. 124 2014 4017 4027
-
(2014)
J. Clin. Invest.
, vol.124
, pp. 4017-4027
-
-
Long, L.1
Toda, C.2
Jeong, J.K.3
Horvath, T.L.4
Diano, S.5
-
58
-
-
84861938799
-
Complex I generated, mitochondrial matrix-directed superoxide is released from the mitochondria through voltage dependent anion channels
-
M.S. Lustgarten, A. Bhattacharya, F.L. Muller, Y.C. Jang, T. Shimizu, T. Shirasawa, A. Richardson, and H. Van Remmen Complex I generated, mitochondrial matrix-directed superoxide is released from the mitochondria through voltage dependent anion channels Biochem. Biophys. Res. Commun. 422 2012 515 521
-
(2012)
Biochem. Biophys. Res. Commun.
, vol.422
, pp. 515-521
-
-
Lustgarten, M.S.1
Bhattacharya, A.2
Muller, F.L.3
Jang, Y.C.4
Shimizu, T.5
Shirasawa, T.6
Richardson, A.7
Van Remmen, H.8
-
59
-
-
84910141948
-
Mitochondrial dynamics and inheritance during cell division, development and disease
-
P. Mishra, and D.C. Chan Mitochondrial dynamics and inheritance during cell division, development and disease Nat. Rev. Mol. Cell Biol. 15 2014 634 646
-
(2014)
Nat. Rev. Mol. Cell Biol.
, vol.15
, pp. 634-646
-
-
Mishra, P.1
Chan, D.C.2
-
60
-
-
58249093939
-
How mitochondria produce reactive oxygen species
-
M.P. Murphy How mitochondria produce reactive oxygen species Biochem. J. 417 2009 1 13
-
(2009)
Biochem. J.
, vol.417
, pp. 1-13
-
-
Murphy, M.P.1
-
61
-
-
84908138540
-
Mitochondrial dynamics in the central regulation of metabolism
-
C.M. Nasrallah, and T.L. Horvath Mitochondrial dynamics in the central regulation of metabolism Nat. Rev. Endocrinol. 10 2014 650 658
-
(2014)
Nat. Rev. Endocrinol.
, vol.10
, pp. 650-658
-
-
Nasrallah, C.M.1
Horvath, T.L.2
-
62
-
-
0038061012
-
A role for uncoupling protein-2 as a regulator of mitochondrial hydrogen peroxide generation
-
A. Negre-Salvayre, C. Hirtz, G. Carrera, R. Cazenave, M. Troly, R. Salvayre, L. Penicaud, and L. Casteilla A role for uncoupling protein-2 as a regulator of mitochondrial hydrogen peroxide generation FASEB journal: official publication of the Federation of American Societies for Experimental Biology 11 1997 809 815
-
(1997)
FASEB Journal: Official Publication of the Federation of American Societies for Experimental Biology
, vol.11
, pp. 809-815
-
-
Negre-Salvayre, A.1
Hirtz, C.2
Carrera, G.3
Cazenave, R.4
Troly, M.5
Salvayre, R.6
Penicaud, L.7
Casteilla, L.8
-
63
-
-
84858376953
-
Mitochondria: in sickness and in health
-
J. Nunnari, and A. Suomalainen Mitochondria: in sickness and in health Cell 148 2012 1145 1159
-
(2012)
Cell
, vol.148
, pp. 1145-1159
-
-
Nunnari, J.1
Suomalainen, A.2
-
64
-
-
79958068191
-
Regulation of yeast chronological life span by TORC1 via adaptive mitochondrial ROS signaling
-
Y. Pan, E.A. Schroeder, A. Ocampo, A. Barrientos, and G.S. Shadel Regulation of yeast chronological life span by TORC1 via adaptive mitochondrial ROS signaling Cell Metab. 13 2011 668 678
-
(2011)
Cell Metab.
, vol.13
, pp. 668-678
-
-
Pan, Y.1
Schroeder, E.A.2
Ocampo, A.3
Barrientos, A.4
Shadel, G.S.5
-
65
-
-
34548604499
-
Glucose sensing by POMC neurons regulates glucose homeostasis and is impaired in obesity
-
L.E. Parton, C.P. Ye, R. Coppari, P.J. Enriori, B. Choi, C.Y. Zhang, C. Xu, C.R. Vianna, N. Balthasar, C.E. Lee, and et al. Glucose sensing by POMC neurons regulates glucose homeostasis and is impaired in obesity Nature 449 2007 228 232
-
(2007)
Nature
, vol.449
, pp. 228-232
-
-
Parton, L.E.1
Ye, C.P.2
Coppari, R.3
Enriori, P.J.4
Choi, B.5
Zhang, C.Y.6
Xu, C.7
Vianna, C.R.8
Balthasar, N.9
Lee, C.E.10
-
66
-
-
69249211307
-
UCP2, a metabolic sensor coupling glucose oxidation to mitochondrial metabolism?
-
C. Pecqueur, C. Alves-Guerra, D. Ricquier, and F. Bouillaud UCP2, a metabolic sensor coupling glucose oxidation to mitochondrial metabolism? IUBMB Life 61 2009 762 767
-
(2009)
IUBMB Life
, vol.61
, pp. 762-767
-
-
Pecqueur, C.1
Alves-Guerra, C.2
Ricquier, D.3
Bouillaud, F.4
-
67
-
-
78650188983
-
An oscillatory switch in mTOR kinase activity sets regulatory T cell responsiveness
-
C. Procaccini, V. De Rosa, M. Galgani, L. Abanni, G. Calì, A. Porcellini, F. Carbone, S. Fontana, T.L. Horvath, A. La Cava, and G. Matarese An oscillatory switch in mTOR kinase activity sets regulatory T cell responsiveness Immunity 33 2010 929 941
-
(2010)
Immunity
, vol.33
, pp. 929-941
-
-
Procaccini, C.1
De Rosa, V.2
Galgani, M.3
Abanni, L.4
Calì, G.5
Porcellini, A.6
Carbone, F.7
Fontana, S.8
Horvath, T.L.9
La Cava, A.10
Matarese, G.11
-
68
-
-
84879430920
-
Sites of reactive oxygen species generation by mitochondria oxidizing different substrates
-
C.L. Quinlan, I.V. Perevoshchikova, M. Hey-Mogensen, A.L. Orr, and M.D. Brand Sites of reactive oxygen species generation by mitochondria oxidizing different substrates Redox Biol. 1 2013 304 312
-
(2013)
Redox Biol.
, vol.1
, pp. 304-312
-
-
Quinlan, C.L.1
Perevoshchikova, I.V.2
Hey-Mogensen, M.3
Orr, A.L.4
Brand, M.D.5
-
69
-
-
0032504772
-
Distribution of the uncoupling protein 2 mRNA in the mouse brain
-
D. Richard, R. Rivest, Q. Huang, F. Bouillaud, D. Sanchis, O. Champigny, and D. Ricquier Distribution of the uncoupling protein 2 mRNA in the mouse brain J. Comp. Neurol. 397 1998 549 560
-
(1998)
J. Comp. Neurol.
, vol.397
, pp. 549-560
-
-
Richard, D.1
Rivest, R.2
Huang, Q.3
Bouillaud, F.4
Sanchis, D.5
Champigny, O.6
Ricquier, D.7
-
70
-
-
0031799223
-
Neonatal brown adipose tissue, UCP1 and the novel uncoupling proteins
-
D. Ricquier Neonatal brown adipose tissue, UCP1 and the novel uncoupling proteins Biochem. Soc. Trans. 26 1998 120 123
-
(1998)
Biochem. Soc. Trans.
, vol.26
, pp. 120-123
-
-
Ricquier, D.1
-
71
-
-
84903936008
-
Unraveling the truth about antioxidants: Mitohormesis explains ROS-induced health benefits
-
M. Ristow Unraveling the truth about antioxidants: mitohormesis explains ROS-induced health benefits Nat. Med. 20 2014 709 711
-
(2014)
Nat. Med.
, vol.20
, pp. 709-711
-
-
Ristow, M.1
-
72
-
-
79959350253
-
Extending life span by increasing oxidative stress
-
M. Ristow, and S. Schmeisser Extending life span by increasing oxidative stress Free Radic. Biol. Med. 51 2011 327 336
-
(2011)
Free Radic. Biol. Med.
, vol.51
, pp. 327-336
-
-
Ristow, M.1
Schmeisser, S.2
-
73
-
-
77952548782
-
How increased oxidative stress promotes longevity and metabolic health: The concept of mitochondrial hormesis (mitohormesis)
-
M. Ristow, and K. Zarse How increased oxidative stress promotes longevity and metabolic health: The concept of mitochondrial hormesis (mitohormesis) Exp. Gerontol. 45 2010 410 418
-
(2010)
Exp. Gerontol.
, vol.45
, pp. 410-418
-
-
Ristow, M.1
Zarse, K.2
-
74
-
-
66649109663
-
Antioxidants prevent health-promoting effects of physical exercise in humans
-
M. Ristow, K. Zarse, A. Oberbach, N. Klöting, M. Birringer, M. Kiehntopf, M. Stumvoll, C.R. Kahn, and M. Blüher Antioxidants prevent health-promoting effects of physical exercise in humans Proc. Natl. Acad. Sci. USA 106 2009 8665 8670
-
(2009)
Proc. Natl. Acad. Sci. USA
, vol.106
, pp. 8665-8670
-
-
Ristow, M.1
Zarse, K.2
Oberbach, A.3
Klöting, N.4
Birringer, M.5
Kiehntopf, M.6
Stumvoll, M.7
Kahn, C.R.8
Blüher, M.9
-
75
-
-
84858791998
-
Mitochondrial quality control: A matter of life and death for neurons
-
E.I. Rugarli, and T. Langer Mitochondrial quality control: A matter of life and death for neurons EMBO J. 31 2012 1336 1349
-
(2012)
EMBO J.
, vol.31
, pp. 1336-1349
-
-
Rugarli, E.I.1
Langer, T.2
-
76
-
-
42049114034
-
Transcriptional paradigms in mammalian mitochondrial biogenesis and function
-
R.C. Scarpulla Transcriptional paradigms in mammalian mitochondrial biogenesis and function Physiol. Rev. 88 2008 611 638
-
(2008)
Physiol. Rev.
, vol.88
, pp. 611-638
-
-
Scarpulla, R.C.1
-
77
-
-
84922800677
-
Protecting the mitochondrial powerhouse
-
M. Scheibye-Knudsen, E.F. Fang, D.L. Croteau, D.M. Wilson 3rd, and V.A. Bohr Protecting the mitochondrial powerhouse Trends Cell Biol. 25 2015 158 170
-
(2015)
Trends Cell Biol.
, vol.25
, pp. 158-170
-
-
Scheibye-Knudsen, M.1
Fang, E.F.2
Croteau, D.L.3
Wilson, D.M.4
Bohr, V.A.5
-
78
-
-
84907993113
-
TOR signaling couples oxygen sensing to lifespan in C. Elegans
-
M. Schieber, and N.S. Chandel TOR signaling couples oxygen sensing to lifespan in C. elegans Cell Rep. 9 2014 9 15
-
(2014)
Cell Rep.
, vol.9
, pp. 9-15
-
-
Schieber, M.1
Chandel, N.S.2
-
79
-
-
84877681309
-
Neuronal ROS signaling rather than AMPK/sirtuin-mediated energy sensing links dietary restriction to lifespan extension
-
S. Schmeisser, S. Priebe, M. Groth, S. Monajembashi, P. Hemmerich, R. Guthke, M. Platzer, and M. Ristow Neuronal ROS signaling rather than AMPK/sirtuin-mediated energy sensing links dietary restriction to lifespan extension Mol. Metab. 2 2013 92 102
-
(2013)
Mol. Metab.
, vol.2
, pp. 92-102
-
-
Schmeisser, S.1
Priebe, S.2
Groth, M.3
Monajembashi, S.4
Hemmerich, P.5
Guthke, R.6
Platzer, M.7
Ristow, M.8
-
80
-
-
84884823792
-
Mitofusin 2 in POMC neurons connects ER stress with leptin resistance and energy imbalance
-
M. Schneeberger, M.O. Dietrich, D. Sebastián, M. Imbernón, C. Castaño, A. Garcia, Y. Esteban, A. Gonzalez-Franquesa, I.C. Rodríguez, A. Bortolozzi, and et al. Mitofusin 2 in POMC neurons connects ER stress with leptin resistance and energy imbalance Cell 155 2013 172 187
-
(2013)
Cell
, vol.155
, pp. 172-187
-
-
Schneeberger, M.1
Dietrich, M.O.2
Sebastián, D.3
Imbernón, M.4
Castaño, C.5
Garcia, A.6
Esteban, Y.7
Gonzalez-Franquesa, A.8
Rodríguez, I.C.9
Bortolozzi, A.10
-
81
-
-
84878797603
-
Epigenetic silencing mediates mitochondria stress-induced longevity
-
E.A. Schroeder, N. Raimundo, and G.S. Shadel Epigenetic silencing mediates mitochondria stress-induced longevity Cell Metab. 17 2013 954 964
-
(2013)
Cell Metab.
, vol.17
, pp. 954-964
-
-
Schroeder, E.A.1
Raimundo, N.2
Shadel, G.S.3
-
82
-
-
34748850786
-
Glucose restriction extends Caenorhabditis elegans life span by inducing mitochondrial respiration and increasing oxidative stress
-
T.J. Schulz, K. Zarse, A. Voigt, N. Urban, M. Birringer, and M. Ristow Glucose restriction extends Caenorhabditis elegans life span by inducing mitochondrial respiration and increasing oxidative stress Cell Metab. 6 2007 280 293
-
(2007)
Cell Metab.
, vol.6
, pp. 280-293
-
-
Schulz, T.J.1
Zarse, K.2
Voigt, A.3
Urban, N.4
Birringer, M.5
Ristow, M.6
-
83
-
-
84868007565
-
Physiological roles of mitochondrial reactive oxygen species
-
L.A. Sena, and N.S. Chandel Physiological roles of mitochondrial reactive oxygen species Mol. Cell 48 2012 158 167
-
(2012)
Mol. Cell
, vol.48
, pp. 158-167
-
-
Sena, L.A.1
Chandel, N.S.2
-
84
-
-
0030920779
-
Mitochondrial DNA maintenance in vertebrates
-
G.S. Shadel, and D.A. Clayton Mitochondrial DNA maintenance in vertebrates Annu. Rev. Biochem. 66 1997 409 435
-
(1997)
Annu. Rev. Biochem.
, vol.66
, pp. 409-435
-
-
Shadel, G.S.1
Clayton, D.A.2
-
85
-
-
84864709300
-
UCP2 induced by natural birth regulates neuronal differentiation of the hippocampus and related adult behavior
-
J. Simon-Areces, M.O. Dietrich, G. Hermes, L.M. Garcia-Segura, M.A. Arevalo, and T.L. Horvath UCP2 induced by natural birth regulates neuronal differentiation of the hippocampus and related adult behavior PLoS ONE 7 2012 e42911
-
(2012)
PLoS ONE
, vol.7
, pp. e42911
-
-
Simon-Areces, J.1
Dietrich, M.O.2
Hermes, G.3
Garcia-Segura, L.M.4
Arevalo, M.A.5
Horvath, T.L.6
-
86
-
-
80053904684
-
Mitochondrial complex III ROS regulate adipocyte differentiation
-
K.V. Tormos, E. Anso, R.B. Hamanaka, J. Eisenbart, J. Joseph, B. Kalyanaraman, and N.S. Chandel Mitochondrial complex III ROS regulate adipocyte differentiation Cell Metab. 14 2011 537 544
-
(2011)
Cell Metab.
, vol.14
, pp. 537-544
-
-
Tormos, K.V.1
Anso, E.2
Hamanaka, R.B.3
Eisenbart, J.4
Joseph, J.5
Kalyanaraman, B.6
Chandel, N.S.7
-
87
-
-
84869228783
-
AgRP neurons: A switch between peripheral carbohydrate and lipid utilization
-
L. Varela, and T.L. Horvath AgRP neurons: A switch between peripheral carbohydrate and lipid utilization EMBO J. 31 2012 4252 4254
-
(2012)
EMBO J.
, vol.31
, pp. 4252-4254
-
-
Varela, L.1
Horvath, T.L.2
-
88
-
-
84892928725
-
UCP2 transports C4 metabolites out of mitochondria, regulating glucose and glutamine oxidation
-
A. Vozza, G. Parisi, F. De Leonardis, F.M. Lasorsa, A. Castegna, D. Amorese, R. Marmo, V.M. Calcagnile, L. Palmieri, D. Ricquier, and et al. UCP2 transports C4 metabolites out of mitochondria, regulating glucose and glutamine oxidation Proc. Natl. Acad. Sci. USA 111 2014 960 965
-
(2014)
Proc. Natl. Acad. Sci. USA
, vol.111
, pp. 960-965
-
-
Vozza, A.1
Parisi, G.2
De Leonardis, F.3
Lasorsa, F.M.4
Castegna, A.5
Amorese, D.6
Marmo, R.7
Calcagnile, V.M.8
Palmieri, L.9
Ricquier, D.10
-
89
-
-
84923325979
-
D-Glucosamine supplementation extends life span of nematodes and of ageing mice
-
S. Weimer, J. Priebs, D. Kuhlow, M. Groth, S. Priebe, J. Mansfeld, T.L. Merry, S. Dubuis, B. Laube, A.F. Pfeiffer, and et al. D-Glucosamine supplementation extends life span of nematodes and of ageing mice Nat. Commun. 5 2014 3563
-
(2014)
Nat. Commun.
, vol.5
, pp. 3563
-
-
Weimer, S.1
Priebs, J.2
Kuhlow, D.3
Groth, M.4
Priebe, S.5
Mansfeld, J.6
Merry, T.L.7
Dubuis, S.8
Laube, B.9
Pfeiffer, A.F.10
-
90
-
-
84928537166
-
Mitochondrial DNA stress primes the antiviral innate immune response
-
A.P. West, W. Khoury-Hanold, M. Staron, M.C. Tal, C.M. Pineda, S.M. Lang, M. Bestwick, B.A. Duguay, N. Raimundo, D.A. MacDuff, and et al. Mitochondrial DNA stress primes the antiviral innate immune response Nature 520 2015 553 557
-
(2015)
Nature
, vol.520
, pp. 553-557
-
-
West, A.P.1
Khoury-Hanold, W.2
Staron, M.3
Tal, M.C.4
Pineda, C.M.5
Lang, S.M.6
Bestwick, M.7
Duguay, B.A.8
Raimundo, N.9
MacDuff, D.A.10
-
92
-
-
42249088093
-
Reconciling the chemistry and biology of reactive oxygen species
-
C.C. Winterbourn Reconciling the chemistry and biology of reactive oxygen species Nat. Chem. Biol. 4 2008 278 286
-
(2008)
Nat. Chem. Biol.
, vol.4
, pp. 278-286
-
-
Winterbourn, C.C.1
-
93
-
-
84885857871
-
Recent advances in reactive oxygen species measurement in biological systems
-
J.F. Woolley, J. Stanicka, and T.G. Cotter Recent advances in reactive oxygen species measurement in biological systems Trends Biochem. Sci. 38 2013 556 565
-
(2013)
Trends Biochem. Sci.
, vol.38
, pp. 556-565
-
-
Woolley, J.F.1
Stanicka, J.2
Cotter, T.G.3
-
94
-
-
84907980823
-
C. Elegans epidermal wounding induces a mitochondrial ROS burst that promotes wound repair
-
S. Xu, and A.D. Chisholm C. elegans epidermal wounding induces a mitochondrial ROS burst that promotes wound repair Dev. Cell 31 2014 48 60
-
(2014)
Dev. Cell
, vol.31
, pp. 48-60
-
-
Xu, S.1
Chisholm, A.D.2
-
95
-
-
84900299463
-
The intrinsic apoptosis pathway mediates the pro-longevity response to mitochondrial ROS in C. Elegans
-
C. Yee, W. Yang, and S. Hekimi The intrinsic apoptosis pathway mediates the pro-longevity response to mitochondrial ROS in C. elegans Cell 157 2014 897 909
-
(2014)
Cell
, vol.157
, pp. 897-909
-
-
Yee, C.1
Yang, W.2
Hekimi, S.3
-
96
-
-
84900295547
-
Mitohormesis
-
J. Yun, and T. Finkel Mitohormesis Cell Metab. 19 2014 757 766
-
(2014)
Cell Metab.
, vol.19
, pp. 757-766
-
-
Yun, J.1
Finkel, T.2
-
97
-
-
84859475161
-
Impaired insulin/IGF1 signaling extends life span by promoting mitochondrial L-proline catabolism to induce a transient ROS signal
-
K. Zarse, S. Schmeisser, M. Groth, S. Priebe, G. Beuster, D. Kuhlow, R. Guthke, M. Platzer, C.R. Kahn, and M. Ristow Impaired insulin/IGF1 signaling extends life span by promoting mitochondrial L-proline catabolism to induce a transient ROS signal Cell Metab. 15 2012 451 465
-
(2012)
Cell Metab.
, vol.15
, pp. 451-465
-
-
Zarse, K.1
Schmeisser, S.2
Groth, M.3
Priebe, S.4
Beuster, G.5
Kuhlow, D.6
Guthke, R.7
Platzer, M.8
Kahn, C.R.9
Ristow, M.10
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