-
1
-
-
0028201732
-
Tolerance, danger, and the extended family
-
Matzinger P (1994) Tolerance, danger, and the extended family. Annu Rev Immunol 12, 991–1045.
-
(1994)
Annu Rev Immunol
, vol.12
, pp. 991-1045
-
-
Matzinger, P.1
-
2
-
-
0032695108
-
Natural adjuvants: endogenous activators of dendritic cells
-
Gallucci S, Lolkema M & Matzinger P (1999) Natural adjuvants: endogenous activators of dendritic cells. Nat Med 5, 1249–1255.
-
(1999)
Nat Med
, vol.5
, pp. 1249-1255
-
-
Gallucci, S.1
Lolkema, M.2
Matzinger, P.3
-
3
-
-
0034614897
-
Consequences of cell death: exposure to necrotic tumor cells, but not primary tissue cells or apoptotic cells, induces the maturation of immunostimulatory dendritic cells
-
Sauter B, Albert ML, Francisco L, Larsson M, Somersan S & Bhardwaj N (2000) Consequences of cell death: exposure to necrotic tumor cells, but not primary tissue cells or apoptotic cells, induces the maturation of immunostimulatory dendritic cells. J Exp Med 191, 423–434.
-
(2000)
J Exp Med
, vol.191
, pp. 423-434
-
-
Sauter, B.1
Albert, M.L.2
Francisco, L.3
Larsson, M.4
Somersan, S.5
Bhardwaj, N.6
-
4
-
-
0034687696
-
Cell injury releases endogenous adjuvants that stimulate cytotoxic T cell responses
-
Shi Y, Zheng W & Rock KL (2000) Cell injury releases endogenous adjuvants that stimulate cytotoxic T cell responses. Proc Natl Acad Sci USA 97, 14590–14595.
-
(2000)
Proc Natl Acad Sci USA
, vol.97
, pp. 14590-14595
-
-
Shi, Y.1
Zheng, W.2
Rock, K.L.3
-
5
-
-
34447116244
-
Identification of a key pathway required for the sterile inflammatory response triggered by dying cells
-
Chen CJ, Kono H, Golenbock D, Reed G, Akira S & Rock KL (2007) Identification of a key pathway required for the sterile inflammatory response triggered by dying cells. Nat Med 13, 851–856.
-
(2007)
Nat Med
, vol.13
, pp. 851-856
-
-
Chen, C.J.1
Kono, H.2
Golenbock, D.3
Reed, G.4
Akira, S.5
Rock, K.L.6
-
6
-
-
41149118513
-
How dying cells alert the immune system to danger
-
Kono H & Rock KL (2008) How dying cells alert the immune system to danger. Nat Rev Immunol 8, 279–289.
-
(2008)
Nat Rev Immunol
, vol.8
, pp. 279-289
-
-
Kono, H.1
Rock, K.L.2
-
7
-
-
47949099098
-
Origin and physiological roles of inflammation
-
Medzhitov R (2008) Origin and physiological roles of inflammation. Nature 454, 428–435.
-
(2008)
Nature
, vol.454
, pp. 428-435
-
-
Medzhitov, R.1
-
8
-
-
84856209374
-
-
13th edn, Wiley-Blackwell, Oxford, in press
-
Delves PJ, Martin SJ, Burton DJ & Roitt IM (2016) Essential Immunology, 13th edn. Wiley-Blackwell, Oxford, in press.
-
(2016)
Essential Immunology
-
-
Delves, P.J.1
Martin, S.J.2
Burton, D.J.3
Roitt, I.M.4
-
10
-
-
78650096176
-
Neutrophil elastase, proteinase 3, and cathepsin G as therapeutic targets in human diseases
-
Korkmaz B, Horwitz MS, Jenne DE & Gauthier F (2010) Neutrophil elastase, proteinase 3, and cathepsin G as therapeutic targets in human diseases. Pharmacol Rev 62, 726–759.
-
(2010)
Pharmacol Rev
, vol.62
, pp. 726-759
-
-
Korkmaz, B.1
Horwitz, M.S.2
Jenne, D.E.3
Gauthier, F.4
-
11
-
-
1542287347
-
Neutrophil extracellular traps kill bacteria
-
Brinkmann V, Reichard U, Goosmann C, Fauler B, Uhlemann Y, Weiss DS, Weinrauch Y & Zychlinsky A (2004) Neutrophil extracellular traps kill bacteria. Science 303, 1532–1535.
-
(2004)
Science
, vol.303
, pp. 1532-1535
-
-
Brinkmann, V.1
Reichard, U.2
Goosmann, C.3
Fauler, B.4
Uhlemann, Y.5
Weiss, D.S.6
Weinrauch, Y.7
Zychlinsky, A.8
-
12
-
-
79952213893
-
The paradox of the neutrophil's role in tissue injury
-
Segel GB, Halterman MW & Lichtman MA (2011) The paradox of the neutrophil's role in tissue injury. J Leukoc Biol 89, 359–372.
-
(2011)
J Leukoc Biol
, vol.89
, pp. 359-372
-
-
Segel, G.B.1
Halterman, M.W.2
Lichtman, M.A.3
-
13
-
-
80755180850
-
Tumor promotion via injury- and death-induced inflammation
-
Kuraishy A, Karin M & Grivennikov SI (2011) Tumor promotion via injury- and death-induced inflammation. Immunity 35, 467–477.
-
(2011)
Immunity
, vol.35
, pp. 467-477
-
-
Kuraishy, A.1
Karin, M.2
Grivennikov, S.I.3
-
14
-
-
74549167783
-
Regulation of adaptive immunity by the innate immune system
-
Iwasaki A & Medzhitov R (2010) Regulation of adaptive immunity by the innate immune system. Science 327, 291–295.
-
(2010)
Science
, vol.327
, pp. 291-295
-
-
Iwasaki, A.1
Medzhitov, R.2
-
15
-
-
0037066427
-
The danger model: a renewed sense of self
-
Matzinger P (2002) The danger model: a renewed sense of self. Science 296, 301–305.
-
(2002)
Science
, vol.296
, pp. 301-305
-
-
Matzinger, P.1
-
16
-
-
84954395099
-
L-1α and inflammasome-independent IL-1β promote neutrophil infiltration following alum vaccination
-
Oleszycka E, Moran HB, Tynan GA, Hearnden CH, Coutts G, Campbell M, Allan SM, Scott CJ & Lavelle EC (2016) L-1α and inflammasome-independent IL-1β promote neutrophil infiltration following alum vaccination. FEBS J 283, 9–24.
-
(2016)
FEBS J
, vol.283
, pp. 9-24
-
-
Oleszycka, E.1
Moran, H.B.2
Tynan, G.A.3
Hearnden, C.H.4
Coutts, G.5
Campbell, M.6
Allan, S.M.7
Scott, C.J.8
Lavelle, E.C.9
-
17
-
-
79961167250
-
DNA released from dying host cells meditates aluminum adjuvant activity
-
Marichal T, Ohata K, Bedoret D, Mesnil C, Sabatel C, Kobiyama K, Lekeux P, Coban C, Akira S, Ishii KJ et al. (2011) DNA released from dying host cells meditates aluminum adjuvant activity. Nat Med 17, 996–1002.
-
(2011)
Nat Med
, vol.17
, pp. 996-1002
-
-
Marichal, T.1
Ohata, K.2
Bedoret, D.3
Mesnil, C.4
Sabatel, C.5
Kobiyama, K.6
Lekeux, P.7
Coban, C.8
Akira, S.9
Ishii, K.J.10
-
18
-
-
77957943307
-
Intravascular danger signals guide neutrophils to sites of sterile inflammation
-
McDonald B, Pittman K, Menezes GB, Hirota SA, Slaba I, Waterhouse CC, Beck PL, Muruve DA & Kubes P (2010) Intravascular danger signals guide neutrophils to sites of sterile inflammation. Science 330, 362–366.
-
(2010)
Science
, vol.330
, pp. 362-366
-
-
McDonald, B.1
Pittman, K.2
Menezes, G.B.3
Hirota, S.A.4
Slaba, I.5
Waterhouse, C.C.6
Beck, P.L.7
Muruve, D.A.8
Kubes, P.9
-
19
-
-
84879420249
-
Neutrophil swarms require LTB4 and integrins at sites of cell death in vivo
-
Lämmermann T, Afonso PV, Angermann BR, Wang JM, Kastenmüller W, Parent CA & Germain RN (2013) Neutrophil swarms require LTB4 and integrins at sites of cell death in vivo. Nature 498, 371–375.
-
(2013)
Nature
, vol.498
, pp. 371-375
-
-
Lämmermann, T.1
Afonso, P.V.2
Angermann, B.R.3
Wang, J.M.4
Kastenmüller, W.5
Parent, C.A.6
Germain, R.N.7
-
20
-
-
84934859494
-
Evaluation of the contribution of multiple DAMPs and DAMP receptors in cell death-induced sterile inflammatory responses
-
Kataoka H, Kono H, Patel Z, Kimura Y & Rock KL (2014) Evaluation of the contribution of multiple DAMPs and DAMP receptors in cell death-induced sterile inflammatory responses. PLoS ONE 9, e104741.
-
(2014)
PLoS ONE
, vol.9
-
-
Kataoka, H.1
Kono, H.2
Patel, Z.3
Kimura, Y.4
Rock, K.L.5
-
21
-
-
77953187290
-
Uric acid promotes an acute inflammatory response to sterile cell death in mice
-
Kono H, Chen CJ, Ontiveros F & Rock KL (2010) Uric acid promotes an acute inflammatory response to sterile cell death in mice. J Clin Invest 120, 1939–1949.
-
(2010)
J Clin Invest
, vol.120
, pp. 1939-1949
-
-
Kono, H.1
Chen, C.J.2
Ontiveros, F.3
Rock, K.L.4
-
22
-
-
77952769075
-
Identification of the cellular sensor that stimulates the inflammatory response to sterile cell death
-
Kono H, Karmarkar D, Iwakura Y & Rock KL (2010) Identification of the cellular sensor that stimulates the inflammatory response to sterile cell death. J Immunol 184, 4470–4478.
-
(2010)
J Immunol
, vol.184
, pp. 4470-4478
-
-
Kono, H.1
Karmarkar, D.2
Iwakura, Y.3
Rock, K.L.4
-
23
-
-
73949118676
-
Necrotic cells trigger a sterile inflammatory response through the Nlrp3 inflammasome
-
Iyer SS, Pulskens WP, Sadler JJ, Butter LM, Teske GJ, Ulland TK, Eisenbarth SC, Florquin S, Flavell RA, Leemans JC et al. (2009) Necrotic cells trigger a sterile inflammatory response through the Nlrp3 inflammasome. Proc Natl Acad Sci USA 106, 20388–20393.
-
(2009)
Proc Natl Acad Sci USA
, vol.106
, pp. 20388-20393
-
-
Iyer, S.S.1
Pulskens, W.P.2
Sadler, J.J.3
Butter, L.M.4
Teske, G.J.5
Ulland, T.K.6
Eisenbarth, S.C.7
Florquin, S.8
Flavell, R.A.9
Leemans, J.C.10
-
24
-
-
33746747096
-
MyD88-dependent IL-1 receptor signaling is essential for gouty inflammation stimulated by monosodium urate crystals
-
Chen CJ, Shi Y, Hearn A, Fitzgerald K, Golenbock D, Reed G, Akira S & Rock KL (2006) MyD88-dependent IL-1 receptor signaling is essential for gouty inflammation stimulated by monosodium urate crystals. J Clin Invest 116, 2262–2271.
-
(2006)
J Clin Invest
, vol.116
, pp. 2262-2271
-
-
Chen, C.J.1
Shi, Y.2
Hearn, A.3
Fitzgerald, K.4
Golenbock, D.5
Reed, G.6
Akira, S.7
Rock, K.L.8
-
25
-
-
36849056773
-
IL-1R1/MyD88 signaling and the inflammasome are essential in pulmonary inflammation and fibrosis in mice
-
Gasse P, Mary C, Guenon I, Noulin N, Charron S, Schnyder-Candrian S, Schnyder B, Akira S, Quesniaux VF, Lagente V et al. (2007) IL-1R1/MyD88 signaling and the inflammasome are essential in pulmonary inflammation and fibrosis in mice. J Clin Invest 117, 3786–3799.
-
(2007)
J Clin Invest
, vol.117
, pp. 3786-3799
-
-
Gasse, P.1
Mary, C.2
Guenon, I.3
Noulin, N.4
Charron, S.5
Schnyder-Candrian, S.6
Schnyder, B.7
Akira, S.8
Quesniaux, V.F.9
Lagente, V.10
-
26
-
-
47849097202
-
Silica crystals and aluminum salts activate the NALP3 inflammasome through phagosomal destabilization
-
Hornung V, Bauernfeind F, Halle A, Samstad EO, Kono H, Rock KL, Fitzgerald KA & Latz E (2008) Silica crystals and aluminum salts activate the NALP3 inflammasome through phagosomal destabilization. Nat Immunol 9, 847–856.
-
(2008)
Nat Immunol
, vol.9
, pp. 847-856
-
-
Hornung, V.1
Bauernfeind, F.2
Halle, A.3
Samstad, E.O.4
Kono, H.5
Rock, K.L.6
Fitzgerald, K.A.7
Latz, E.8
-
27
-
-
70949103587
-
Role of proinflammatory cytokines IL-18 and IL-1beta in bleomycin-induced lung injury in humans and mice
-
Hoshino T, Okamoto M, Sakazaki Y, Kato S, Young HA & Aizawa H (2009) Role of proinflammatory cytokines IL-18 and IL-1beta in bleomycin-induced lung injury in humans and mice. Am J Respir Cell Mol Biol 41, 661–670.
-
(2009)
Am J Respir Cell Mol Biol
, vol.41
, pp. 661-670
-
-
Hoshino, T.1
Okamoto, M.2
Sakazaki, Y.3
Kato, S.4
Young, H.A.5
Aizawa, H.6
-
28
-
-
77951800951
-
NLRP3 inflammasomes are required for atherogenesis and activated by cholesterol crystals
-
Duewell P, Kono H, Rayner KJ, Sirois CM, Vladimer G, Bauernfeind FG, Abela GS, Franchi L, Nuñez G, Schnurr M et al. (2010) NLRP3 inflammasomes are required for atherogenesis and activated by cholesterol crystals. Nature 464, 1357–1361.
-
(2010)
Nature
, vol.464
, pp. 1357-1361
-
-
Duewell, P.1
Kono, H.2
Rayner, K.J.3
Sirois, C.M.4
Vladimer, G.5
Bauernfeind, F.G.6
Abela, G.S.7
Franchi, L.8
Nuñez, G.9
Schnurr, M.10
-
29
-
-
84879419779
-
Damage-associated molecular patterns control neutrophil recruitment
-
Pittman K & Kubes P (2013) Damage-associated molecular patterns control neutrophil recruitment. J Innate Immun 5, 315–323.
-
(2013)
J Innate Immun
, vol.5
, pp. 315-323
-
-
Pittman, K.1
Kubes, P.2
-
30
-
-
0037928705
-
Recombinant human heat shock protein 60 does not induce the release of tumor necrosis factor alpha from murine macrophages
-
Gao B & Tsan MF (2003) Recombinant human heat shock protein 60 does not induce the release of tumor necrosis factor alpha from murine macrophages. J Biol Chem 278, 22523–22529.
-
(2003)
J Biol Chem
, vol.278
, pp. 22523-22529
-
-
Gao, B.1
Tsan, M.F.2
-
31
-
-
33845893860
-
Pivotal advance: analysis of proinflammatory activity of highly purified eukaryotic recombinant HMGB1 (amphoterin)
-
Rouhiainen A, Tumova S, Valmu L, Kalkkinen N & Rauvala H (2007) Pivotal advance: analysis of proinflammatory activity of highly purified eukaryotic recombinant HMGB1 (amphoterin). J Leukoc Biol 81, 49–58.
-
(2007)
J Leukoc Biol
, vol.81
, pp. 49-58
-
-
Rouhiainen, A.1
Tumova, S.2
Valmu, L.3
Kalkkinen, N.4
Rauvala, H.5
-
32
-
-
34247236200
-
Toll-like receptor 9-dependent activation by DNA-containing immune complexes is mediated by HMGB1 and RAGE
-
Tian J, Avalos AM, Mao SY, Chen B, Senthil K, Wu H, Parroche P, Drabic S, Golenbock D, Sirois C et al. (2007) Toll-like receptor 9-dependent activation by DNA-containing immune complexes is mediated by HMGB1 and RAGE. Nat Immunol 8, 487–496.
-
(2007)
Nat Immunol
, vol.8
, pp. 487-496
-
-
Tian, J.1
Avalos, A.M.2
Mao, S.Y.3
Chen, B.4
Senthil, K.5
Wu, H.6
Parroche, P.7
Drabic, S.8
Golenbock, D.9
Sirois, C.10
-
33
-
-
34250837518
-
A novel role for HMGB1 in TLR9-mediated inflammatory responses to CpG-DNA
-
Ivanov S, Dragoi AM, Wang X, Dallacosta C, Louten J, Musco G, Sitia G, Yap GS, Wan Y, Biron CA et al. (2007) A novel role for HMGB1 in TLR9-mediated inflammatory responses to CpG-DNA. Blood 110, 1970–1981.
-
(2007)
Blood
, vol.110
, pp. 1970-1981
-
-
Ivanov, S.1
Dragoi, A.M.2
Wang, X.3
Dallacosta, C.4
Louten, J.5
Musco, G.6
Sitia, G.7
Yap, G.S.8
Wan, Y.9
Biron, C.A.10
-
34
-
-
44449162626
-
High mobility group box 1 protein binding to lipopolysaccharide facilitates transfer of lipopolysaccharide to CD14 and enhances lipopolysaccharide-mediated TNF-α production in human monocytes
-
Youn JH, Oh YJ, Kim ES, Choi JE & Shin JS (2008) High mobility group box 1 protein binding to lipopolysaccharide facilitates transfer of lipopolysaccharide to CD14 and enhances lipopolysaccharide-mediated TNF-α production in human monocytes. J Immunol 180, 5067–5074.
-
(2008)
J Immunol
, vol.180
, pp. 5067-5074
-
-
Youn, J.H.1
Oh, Y.J.2
Kim, E.S.3
Choi, J.E.4
Shin, J.S.5
-
35
-
-
42149192003
-
HMGB1 develops enhanced proinflammatory activity by binding to cytokines
-
Sha Y, Zmijewski J, Xu Z & Abraham E (2008) HMGB1 develops enhanced proinflammatory activity by binding to cytokines. J Immunol 180, 2531–2537.
-
(2008)
J Immunol
, vol.180
, pp. 2531-2537
-
-
Sha, Y.1
Zmijewski, J.2
Xu, Z.3
Abraham, E.4
-
36
-
-
70149098507
-
The alarmin HMGB1 acts in synergy with endogenous and exogenous danger signals to promote inflammation
-
Hreggvidsdottir HS, Ostberg T, Wähämaa H, Schierbeck H, Aveberger AC, Klevenvall L, Palmblad K, Ottosson L, Andersson U & Harris HE (2009) The alarmin HMGB1 acts in synergy with endogenous and exogenous danger signals to promote inflammation. J Leukoc Biol 86, 655–662.
-
(2009)
J Leukoc Biol
, vol.86
, pp. 655-662
-
-
Hreggvidsdottir, H.S.1
Ostberg, T.2
Wähämaa, H.3
Schierbeck, H.4
Aveberger, A.C.5
Klevenvall, L.6
Palmblad, K.7
Ottosson, L.8
Andersson, U.9
Harris, H.E.10
-
37
-
-
77954005130
-
Endogenous ligands of TLR2 and TLR4: agonists or assistants?
-
Erridge C (2009) Endogenous ligands of TLR2 and TLR4: agonists or assistants? J Leukoc Biol 87, 989–999.
-
(2009)
J Leukoc Biol
, vol.87
, pp. 989-999
-
-
Erridge, C.1
-
38
-
-
84455192723
-
Real-time imaging reveals that P2Y2 and P2Y12 receptor agonists are not chemoattractants and macrophage chemotaxis to complement C5a is phosphatidylinositol 3-kinase (PI3K)- and p38 mitogen-activated protein kinase (MAPK)-independent
-
Isfort K, Ebert F, Bornhorst J, Sargin S, Kardakaris R, Pasparakis M, Bähler M, Schwerdtle T, Schwab A & Hanley PJ (2011) Real-time imaging reveals that P2Y2 and P2Y12 receptor agonists are not chemoattractants and macrophage chemotaxis to complement C5a is phosphatidylinositol 3-kinase (PI3K)- and p38 mitogen-activated protein kinase (MAPK)-independent. J Biol Chem 286, 44776–44787.
-
(2011)
J Biol Chem
, vol.286
, pp. 44776-44787
-
-
Isfort, K.1
Ebert, F.2
Bornhorst, J.3
Sargin, S.4
Kardakaris, R.5
Pasparakis, M.6
Bähler, M.7
Schwerdtle, T.8
Schwab, A.9
Hanley, P.J.10
-
39
-
-
84937577488
-
Diverse activators of the NLRP3 inflammasome promote IL-1β secretion by triggering necrosis
-
Cullen SP, Kearney CJ, Clancy DM & Martin SJ (2015) Diverse activators of the NLRP3 inflammasome promote IL-1β secretion by triggering necrosis. Cell Rep 11, 1535–1548.
-
(2015)
Cell Rep
, vol.11
, pp. 1535-1548
-
-
Cullen, S.P.1
Kearney, C.J.2
Clancy, D.M.3
Martin, S.J.4
-
40
-
-
68249137289
-
Suppression of interleukin-33 bioactivity through proteolysis by apoptotic caspases
-
Lüthi AU, Cullen SP, McNeela EA, Duriez PJ, Afonina IS, Sheridan C, Brumatti G, Taylor RC, Kersse K, Vandenabeele P et al. (2009) Suppression of interleukin-33 bioactivity through proteolysis by apoptotic caspases. Immunity 31, 84–98.
-
(2009)
Immunity
, vol.31
, pp. 84-98
-
-
Lüthi, A.U.1
Cullen, S.P.2
McNeela, E.A.3
Duriez, P.J.4
Afonina, I.S.5
Sheridan, C.6
Brumatti, G.7
Taylor, R.C.8
Kersse, K.9
Vandenabeele, P.10
-
41
-
-
84958115094
-
Neutrophil-derived proteases escalate inflammation through activation of IL-36 family cytokines
-
Henry CM, Sullivan GP, Clancy DM, Afonina IS, Kulms D & Martin SJ (2016) Neutrophil-derived proteases escalate inflammation through activation of IL-36 family cytokines. Cell Rep 14, 708–722.
-
(2016)
Cell Rep
, vol.14
, pp. 708-722
-
-
Henry, C.M.1
Sullivan, G.P.2
Clancy, D.M.3
Afonina, I.S.4
Kulms, D.5
Martin, S.J.6
-
42
-
-
47249089097
-
IL-1, IL-18, and IL-33 families of cytokines
-
Arend WP, Palmer G & Gabay C (2008) IL-1, IL-18, and IL-33 families of cytokines. Immunol Rev 223, 20–38.
-
(2008)
Immunol Rev
, vol.223
, pp. 20-38
-
-
Arend, W.P.1
Palmer, G.2
Gabay, C.3
-
43
-
-
75549091673
-
The IL-1 family: regulators of immunity
-
Sims JE & Smith DE (2010) The IL-1 family: regulators of immunity. Nat Rev Immunol 10, 89–102.
-
(2010)
Nat Rev Immunol
, vol.10
, pp. 89-102
-
-
Sims, J.E.1
Smith, D.E.2
-
44
-
-
84937605509
-
Proteolytic processing of interleukin-1 family cytokines: variations on a common theme
-
Afonina IS, Müller C, Martin SJ & Beyaert R (2015) Proteolytic processing of interleukin-1 family cytokines: variations on a common theme. Immunity 42, 991–1004.
-
(2015)
Immunity
, vol.42
, pp. 991-1004
-
-
Afonina, I.S.1
Müller, C.2
Martin, S.J.3
Beyaert, R.4
-
45
-
-
0026507126
-
A novel heterodimeric cysteine protease is required for interleukin-1β processing in monocytes
-
Thornberry NA, Bull HG, Calaycay JR, Chapman KT, Howard AD, Kostura MJ, Miller DK, Molineaux SM, Weider JR, Aunins J et al. (1992) A novel heterodimeric cysteine protease is required for interleukin-1β processing in monocytes. Nature 356, 768–774.
-
(1992)
Nature
, vol.356
, pp. 768-774
-
-
Thornberry, N.A.1
Bull, H.G.2
Calaycay, J.R.3
Chapman, K.T.4
Howard, A.D.5
Kostura, M.J.6
Miller, D.K.7
Molineaux, S.M.8
Weider, J.R.9
Aunins, J.10
-
46
-
-
15644369352
-
Activation of interferon-gamma inducing factor mediated by interleukin-1beta converting enzyme
-
Gu Y, Kuida K, Tsutsui H, Ku G, Hsiao K, Fleming MA, Hayashi N, Higashino K, Okamura H, Nakanishi K et al. (1997) Activation of interferon-gamma inducing factor mediated by interleukin-1beta converting enzyme. Science 273, 206–209.
-
(1997)
Science
, vol.273
, pp. 206-209
-
-
Gu, Y.1
Kuida, K.2
Tsutsui, H.3
Ku, G.4
Hsiao, K.5
Fleming, M.A.6
Hayashi, N.7
Higashino, K.8
Okamura, H.9
Nakanishi, K.10
-
47
-
-
1842640230
-
Interleukin (IL)-1F6, IL-1F8, and IL-1F9 signal through IL-1Rrp2 and IL-1RAcP to activate the pathway leading to NF-kappaB and MAPKs
-
Towne JE, Garka KE, Renshaw BR, Virca GD & Sims JE (2004) Interleukin (IL)-1F6, IL-1F8, and IL-1F9 signal through IL-1Rrp2 and IL-1RAcP to activate the pathway leading to NF-kappaB and MAPKs. J Biol Chem 279, 13677–13688.
-
(2004)
J Biol Chem
, vol.279
, pp. 13677-13688
-
-
Towne, J.E.1
Garka, K.E.2
Renshaw, B.R.3
Virca, G.D.4
Sims, J.E.5
-
48
-
-
82455175456
-
Granzyme B-dependent proteolysis acts as a switch to enhance the pro-inflammatory activity of IL-1alpha
-
Afonina IA, Tynan GA, Logue SE, Cullen SP, Bots M, Lüthi AU, Reeves EP, McElvaney NG, Medema JP, Lavelle EC et al. (2011) Granzyme B-dependent proteolysis acts as a switch to enhance the pro-inflammatory activity of IL-1alpha. Mol Cell 44, 265–278.
-
(2011)
Mol Cell
, vol.44
, pp. 265-278
-
-
Afonina, I.A.1
Tynan, G.A.2
Logue, S.E.3
Cullen, S.P.4
Bots, M.5
Lüthi, A.U.6
Reeves, E.P.7
McElvaney, N.G.8
Medema, J.P.9
Lavelle, E.C.10
-
49
-
-
84908541933
-
Central domain of IL-33 is cleaved by mast cell proteases for potent activation of group-2 innate lymphoid cells
-
Lefrançais E, Duval A, Mirey E, Roga S, Espinosa E, Cayrol C & Girard JP (2014) Central domain of IL-33 is cleaved by mast cell proteases for potent activation of group-2 innate lymphoid cells. Proc Natl Acad Sci USA 111, 15502–15507.
-
(2014)
Proc Natl Acad Sci USA
, vol.111
, pp. 15502-15507
-
-
Lefrançais, E.1
Duval, A.2
Mirey, E.3
Roga, S.4
Espinosa, E.5
Cayrol, C.6
Girard, J.P.7
-
50
-
-
84857134135
-
IL-33 is processed into mature bioactive forms by neutrophil elastase and cathepsin G
-
Lefrançais E, Roga S, Gautier V, Gonzalez-de-Peredo A, Monserrat B, Girard JP & Cayrol C (2012) IL-33 is processed into mature bioactive forms by neutrophil elastase and cathepsin G. Proc Natl Acad Sci USA 31, 1673–1678.
-
(2012)
Proc Natl Acad Sci USA
, vol.31
, pp. 1673-1678
-
-
Lefrançais, E.1
Roga, S.2
Gautier, V.3
Gonzalez-de-Peredo, A.4
Monserrat, B.5
Girard, J.P.6
Cayrol, C.7
-
51
-
-
84874217124
-
TIR8/SIGIRR is an interleukin-1 receptor/toll like receptor family member with regulatory functions in inflammation and immunity
-
Riva F, Bonavita E, Barbati E, Muzio M, Mantovani A & Garlanda C (2012) TIR8/SIGIRR is an interleukin-1 receptor/toll like receptor family member with regulatory functions in inflammation and immunity. Front Immunol 3, A322.
-
(2012)
Front Immunol
, vol.3
, pp. 322
-
-
Riva, F.1
Bonavita, E.2
Barbati, E.3
Muzio, M.4
Mantovani, A.5
Garlanda, C.6
-
52
-
-
84901807090
-
The TLR and IL-1 signalling network at a glance
-
Cohen P (2014) The TLR and IL-1 signalling network at a glance. J Cell Sci 127, 2383–2390.
-
(2014)
J Cell Sci
, vol.127
, pp. 2383-2390
-
-
Cohen, P.1
-
53
-
-
62649139025
-
Immunological and inflammatory functions of the interleukin-1 family
-
Dinarello CA (2009) Immunological and inflammatory functions of the interleukin-1 family. Annu Rev Immunol 27, 519–550.
-
(2009)
Annu Rev Immunol
, vol.27
, pp. 519-550
-
-
Dinarello, C.A.1
-
54
-
-
84940380928
-
A distinct function of regulatory T cells in tissue protection
-
Arpaia N, Green JA, Moltedo B, Arvey A, Hemmers S, Yuan S, Treuting PM & Rudensky AY (2015) A distinct function of regulatory T cells in tissue protection. Cell 162, 1078–1089.
-
(2015)
Cell
, vol.162
, pp. 1078-1089
-
-
Arpaia, N.1
Green, J.A.2
Moltedo, B.3
Arvey, A.4
Hemmers, S.5
Yuan, S.6
Treuting, P.M.7
Rudensky, A.Y.8
-
55
-
-
34249882513
-
IL-33 and ST2 comprise a critical biomechanically induced and cardioprotective signaling system
-
Sanada S, Hakuno D, Higgins LJ, Schreiter ER, McKenzie AN & Lee RT (2007) IL-33 and ST2 comprise a critical biomechanically induced and cardioprotective signaling system. J Clin Invest 117, 1538–1549.
-
(2007)
J Clin Invest
, vol.117
, pp. 1538-1549
-
-
Sanada, S.1
Hakuno, D.2
Higgins, L.J.3
Schreiter, E.R.4
McKenzie, A.N.5
Lee, R.T.6
-
56
-
-
84874248044
-
Intracellular interleukin-1 receptor 2 binding prevents cleavage and activity of interleukin-1α, controlling necrosis-induced sterile inflammation
-
Zheng Y, Humphry M, Maguire JJ, Bennett MR & Clarke MC (2013) Intracellular interleukin-1 receptor 2 binding prevents cleavage and activity of interleukin-1α, controlling necrosis-induced sterile inflammation. Immunity 38, 285–295.
-
(2013)
Immunity
, vol.38
, pp. 285-295
-
-
Zheng, Y.1
Humphry, M.2
Maguire, J.J.3
Bennett, M.R.4
Clarke, M.C.5
-
57
-
-
84939499267
-
IL-33 released by alum is responsible for early cytokine production and has adjuvant properties
-
Rose WA, Okragly AJ, Patel CN & Benschop RJ (2015) IL-33 released by alum is responsible for early cytokine production and has adjuvant properties. Sci Rep 5, 13146.
-
(2015)
Sci Rep
, vol.5
, pp. 13146
-
-
Rose, W.A.1
Okragly, A.J.2
Patel, C.N.3
Benschop, R.J.4
-
58
-
-
84943546474
-
Interleukin-1α activity in necrotic endothelial cells is controlled by caspase-1 cleavage of interleukin-1 receptor-2: implications for allograft rejection
-
Burzynski LC, Humphry M, Bennett MR & Clarke MC (2015) Interleukin-1α activity in necrotic endothelial cells is controlled by caspase-1 cleavage of interleukin-1 receptor-2: implications for allograft rejection. J Biol Chem 290, 25188–25196.
-
(2015)
J Biol Chem
, vol.290
, pp. 25188-25196
-
-
Burzynski, L.C.1
Humphry, M.2
Bennett, M.R.3
Clarke, M.C.4
-
59
-
-
84942856523
-
Caspase-11 cleaves gasdermin D for non-canonical inflammasome signalling
-
Kayagaki N, Stowe IB, Lee BL, O'Rourke K, Anderson K, Warming S, Cuellar T, Haley B, Roose-Girma M, Phung QT et al. (2015) Caspase-11 cleaves gasdermin D for non-canonical inflammasome signalling. Nature 526, 666–671.
-
(2015)
Nature
, vol.526
, pp. 666-671
-
-
Kayagaki, N.1
Stowe, I.B.2
Lee, B.L.3
O'Rourke, K.4
Anderson, K.5
Warming, S.6
Cuellar, T.7
Haley, B.8
Roose-Girma, M.9
Phung, Q.T.10
-
60
-
-
84942892037
-
Cleavage of GSDMD by inflammatory caspases determines pyroptotic cell death
-
Shi J, Zhao Y, Wang K, Shi X, Wang Y, Huang H, Zhuang Y, Cai T, Wang F & Shao F (2015) Cleavage of GSDMD by inflammatory caspases determines pyroptotic cell death. Nature 526, 660–665.
-
(2015)
Nature
, vol.526
, pp. 660-665
-
-
Shi, J.1
Zhao, Y.2
Wang, K.3
Shi, X.4
Wang, Y.5
Huang, H.6
Zhuang, Y.7
Cai, T.8
Wang, F.9
Shao, F.10
-
61
-
-
0028984948
-
Mice deficient in IL-1 beta-converting enzyme are defective in production of mature IL-1 beta and resistant to endotoxic shock
-
Li P, Allen H, Banerjee S, Franklin S, Herzog L, Johnston C, McDowell J, Paskind M, Rodman L, Salfeld J et al. (1995) Mice deficient in IL-1 beta-converting enzyme are defective in production of mature IL-1 beta and resistant to endotoxic shock. Cell 80, 401–411.
-
(1995)
Cell
, vol.80
, pp. 401-411
-
-
Li, P.1
Allen, H.2
Banerjee, S.3
Franklin, S.4
Herzog, L.5
Johnston, C.6
McDowell, J.7
Paskind, M.8
Rodman, L.9
Salfeld, J.10
-
62
-
-
32944468985
-
Gout-associated uric acid crystals activate the NALP3 inflammasome
-
Martinon F, Pétrilli V, Mayor A, Tardivel A & Tschopp J (2006) Gout-associated uric acid crystals activate the NALP3 inflammasome. Nature 440, 237–241.
-
(2006)
Nature
, vol.440
, pp. 237-241
-
-
Martinon, F.1
Pétrilli, V.2
Mayor, A.3
Tardivel, A.4
Tschopp, J.5
-
63
-
-
84953231157
-
Cutting edge: IL-36 receptor promotes resolution of intestinal damage
-
Medina-Contreras O, Harusato A, Nishio H, Flannigan KL, Ngo V, Leoni G, Neumann PA, Geem D, Lili LN, Ramadas RA et al. (2016) Cutting edge: IL-36 receptor promotes resolution of intestinal damage. J Immunol 196, 34–38.
-
(2016)
J Immunol
, vol.196
, pp. 34-38
-
-
Medina-Contreras, O.1
Harusato, A.2
Nishio, H.3
Flannigan, K.L.4
Ngo, V.5
Leoni, G.6
Neumann, P.A.7
Geem, D.8
Lili, L.N.9
Ramadas, R.A.10
-
64
-
-
84874269082
-
The transcription of the alarmin cytokine interleukin-1 alpha is controlled by hypoxia inducible factors 1 and 2 alpha in hypoxic cells
-
Rider P, Kaplanov I, Romzova M, Bernardis L, Braiman A, Voronov E & Apte RN (2012) The transcription of the alarmin cytokine interleukin-1 alpha is controlled by hypoxia inducible factors 1 and 2 alpha in hypoxic cells. Front Immunol 3, 290.
-
(2012)
Front Immunol
, vol.3
, pp. 290
-
-
Rider, P.1
Kaplanov, I.2
Romzova, M.3
Bernardis, L.4
Braiman, A.5
Voronov, E.6
Apte, R.N.7
-
65
-
-
43249125839
-
Innate immune activation through Nalp3 inflammasome sensing of asbestos and silica
-
Dostert C, Pétrilli V, Van Bruggen R, Steele C, Mossman BT & Tschopp J (2008) Innate immune activation through Nalp3 inflammasome sensing of asbestos and silica. Science 320, 674–677.
-
(2008)
Science
, vol.320
, pp. 674-677
-
-
Dostert, C.1
Pétrilli, V.2
Van Bruggen, R.3
Steele, C.4
Mossman, B.T.5
Tschopp, J.6
-
66
-
-
78650610580
-
Nanoparticles activate the NLR pyrin domain containing 3 (Nlrp3) inflammasome and cause pulmonary inflammation through release of IL-1α and IL-1β
-
Yazdi AS, Guarda G, Riteau N, Drexler SK, Tardivel A, Couillin I & Tschopp J (2010) Nanoparticles activate the NLR pyrin domain containing 3 (Nlrp3) inflammasome and cause pulmonary inflammation through release of IL-1α and IL-1β. Proc Natl Acad Sci USA 107, 19449–19454.
-
(2010)
Proc Natl Acad Sci USA
, vol.107
, pp. 19449-19454
-
-
Yazdi, A.S.1
Guarda, G.2
Riteau, N.3
Drexler, S.K.4
Tardivel, A.5
Couillin, I.6
Tschopp, J.7
-
67
-
-
84866552287
-
The IL-1-dependent sterile inflammatory response has a substantial caspase-1-independent component that requires cathepsin C
-
Kono H, Orlowski GM, Patel Z & Rock KL (2012) The IL-1-dependent sterile inflammatory response has a substantial caspase-1-independent component that requires cathepsin C. J Immunol 189, 3734–3740.
-
(2012)
J Immunol
, vol.189
, pp. 3734-3740
-
-
Kono, H.1
Orlowski, G.M.2
Patel, Z.3
Rock, K.L.4
-
68
-
-
0037432179
-
Identification of serum soluble ST2 receptor as a novel heart failure biomarker
-
Weinberg EO, Shimpo M, Hurwitz S, Tominaga S, Rouleau JL & Lee RT (2003) Identification of serum soluble ST2 receptor as a novel heart failure biomarker. Circulation 107, 721–726.
-
(2003)
Circulation
, vol.107
, pp. 721-726
-
-
Weinberg, E.O.1
Shimpo, M.2
Hurwitz, S.3
Tominaga, S.4
Rouleau, J.L.5
Lee, R.T.6
-
69
-
-
2442621252
-
Serum levels of the interleukin-1 receptor family member ST2 predict mortalityand clinical outcome in acute myocardial infarction
-
Shimpo M, Morrow DA, Weinberg EO, Sabatine MS, Murphy SA, Antman EM & Lee RT (2004) Serum levels of the interleukin-1 receptor family member ST2 predict mortalityand clinical outcome in acute myocardial infarction. Circulation 109, 2186–2190.
-
(2004)
Circulation
, vol.109
, pp. 2186-2190
-
-
Shimpo, M.1
Morrow, D.A.2
Weinberg, E.O.3
Sabatine, M.S.4
Murphy, S.A.5
Antman, E.M.6
Lee, R.T.7
-
70
-
-
84923384574
-
Application of IL-36 receptor antagonist weakens CCL20 expression and impairs recovery in the late phase of murine acetaminophen-induced liver injury
-
Scheiermann P, Bachmann M, Härdle L, Pleli T, Piiper A, Zwissler B, Pfeilschifter J & Mühl H (2015) Application of IL-36 receptor antagonist weakens CCL20 expression and impairs recovery in the late phase of murine acetaminophen-induced liver injury. Sci Rep 5, 8521.
-
(2015)
Sci Rep
, vol.5
, pp. 8521
-
-
Scheiermann, P.1
Bachmann, M.2
Härdle, L.3
Pleli, T.4
Piiper, A.5
Zwissler, B.6
Pfeilschifter, J.7
Mühl, H.8
-
71
-
-
84860390352
-
Interleukin-36-receptor antagonist deficiency and generalized pustular psoriasis
-
Marrakchi S, Guigue P, Renshaw BR, Puel A, Pei XY, Fraitag S, Zribi J, Bal E, Cluzeau C, Chrabieh M et al. (2011) Interleukin-36-receptor antagonist deficiency and generalized pustular psoriasis. N Engl J Med 365, 620–628.
-
(2011)
N Engl J Med
, vol.365
, pp. 620-628
-
-
Marrakchi, S.1
Guigue, P.2
Renshaw, B.R.3
Puel, A.4
Pei, X.Y.5
Fraitag, S.6
Zribi, J.7
Bal, E.8
Cluzeau, C.9
Chrabieh, M.10
-
72
-
-
84871608956
-
Mutation analysis of the IL36RN gene in 14 Japanese patients with generalized pustular psoriasis
-
Farooq M, Nakai H, Fujimoto A, Fujikawa H, Matsuyama A, Kariya N, Aizawa A, Fujiwara H, Ito M & Shimomura Y (2013) Mutation analysis of the IL36RN gene in 14 Japanese patients with generalized pustular psoriasis. Hum Mutat 34, 176–183.
-
(2013)
Hum Mutat
, vol.34
, pp. 176-183
-
-
Farooq, M.1
Nakai, H.2
Fujimoto, A.3
Fujikawa, H.4
Matsuyama, A.5
Kariya, N.6
Aizawa, A.7
Fujiwara, H.8
Ito, M.9
Shimomura, Y.10
-
73
-
-
66649121678
-
An autoinflammatory disease with deficiency of the interleukin-1-receptor antagonist
-
Aksentijevich I, Masters SL, Ferguson PJ, Dancey P, Frenkel J, van Royen-Kerkhoff A, Laxer R, Tedgård U, Cowen EW, Pham TH et al. (2009) An autoinflammatory disease with deficiency of the interleukin-1-receptor antagonist. N Engl J Med 360, 2426–2437.
-
(2009)
N Engl J Med
, vol.360
, pp. 2426-2437
-
-
Aksentijevich, I.1
Masters, S.L.2
Ferguson, P.J.3
Dancey, P.4
Frenkel, J.5
van Royen-Kerkhoff, A.6
Laxer, R.7
Tedgård, U.8
Cowen, E.W.9
Pham, T.H.10
-
74
-
-
66649113371
-
An autoinflammatory disease due to homozygous deletion of the IL1RN locus
-
Reddy S, Jia S, Geoffrey R, Lorier R, Suchi M, Broeckel U, Hessner MJ & Verbsky J (2009) An autoinflammatory disease due to homozygous deletion of the IL1RN locus. N Engl J Med 360, 2438–2444.
-
(2009)
N Engl J Med
, vol.360
, pp. 2438-2444
-
-
Reddy, S.1
Jia, S.2
Geoffrey, R.3
Lorier, R.4
Suchi, M.5
Broeckel, U.6
Hessner, M.J.7
Verbsky, J.8
-
76
-
-
84861435630
-
A perspective on mammalian caspases as positive and negative regulators of inflammation
-
Martin SJ, Henry CM & Cullen SP (2012) A perspective on mammalian caspases as positive and negative regulators of inflammation. Mol Cell 46, 387–397.
-
(2012)
Mol Cell
, vol.46
, pp. 387-397
-
-
Martin, S.J.1
Henry, C.M.2
Cullen, S.P.3
-
77
-
-
67049158193
-
The IL-1-like cytokine IL-33 is inactivated after maturation by caspase-1
-
Cayrol C & Girard JP (2009) The IL-1-like cytokine IL-33 is inactivated after maturation by caspase-1. Proc Natl Acad Sci USA 106, 9021–9026.
-
(2009)
Proc Natl Acad Sci USA
, vol.106
, pp. 9021-9026
-
-
Cayrol, C.1
Girard, J.P.2
-
78
-
-
77249085646
-
Differential release of chromatin-bound IL-1alpha discriminates between necrotic and apoptotic cell death by the ability to induce sterile inflammation
-
Cohen I, Rider P, Carmi Y, Braiman A, Dotan S, White MR, Voronov E, Martin MU, Dinarello CA & Apte RN (2010) Differential release of chromatin-bound IL-1alpha discriminates between necrotic and apoptotic cell death by the ability to induce sterile inflammation. Proc Natl Acad Sci USA 107, 2574–2579.
-
(2010)
Proc Natl Acad Sci USA
, vol.107
, pp. 2574-2579
-
-
Cohen, I.1
Rider, P.2
Carmi, Y.3
Braiman, A.4
Dotan, S.5
White, M.R.6
Voronov, E.7
Martin, M.U.8
Dinarello, C.A.9
Apte, R.N.10
-
79
-
-
82155183309
-
IL-36R ligands are potent regulators of dendritic and T cells
-
Vigne S, Palmer G, Lamacchia C, Martin P, Talabot-Ayer D, Rodriguez E, Ronchi F, Sallusto F, Dinh H, Sims JE et al. (2011) IL-36R ligands are potent regulators of dendritic and T cells. Blood 118, 5813–5823.
-
(2011)
Blood
, vol.118
, pp. 5813-5823
-
-
Vigne, S.1
Palmer, G.2
Lamacchia, C.3
Martin, P.4
Talabot-Ayer, D.5
Rodriguez, E.6
Ronchi, F.7
Sallusto, F.8
Dinh, H.9
Sims, J.E.10
-
80
-
-
84890235827
-
The interleukin-1 family: back to the future
-
Garlanda C, Dinarello CA & Mantovani A (2013) The interleukin-1 family: back to the future. Immunity 39, 1003–1018.
-
(2013)
Immunity
, vol.39
, pp. 1003-1018
-
-
Garlanda, C.1
Dinarello, C.A.2
Mantovani, A.3
-
81
-
-
84964300561
-
IL-1 is a critical regulator of group 2 innate lymphoid cell function and plasticity
-
Ohne Y, Silver JS, Thompson-Snipes L, Collet MA, Blanck JP, Cantarel BL, Copenhaver AM, Humbles AA & Liu YJ (2016) IL-1 is a critical regulator of group 2 innate lymphoid cell function and plasticity. Nat Immunol 17, 646–655.
-
(2016)
Nat Immunol
, vol.17
, pp. 646-655
-
-
Ohne, Y.1
Silver, J.S.2
Thompson-Snipes, L.3
Collet, M.A.4
Blanck, J.P.5
Cantarel, B.L.6
Copenhaver, A.M.7
Humbles, A.A.8
Liu, Y.J.9
-
82
-
-
27744446058
-
IL-33, an interleukin-1-like cytokine that signals via the IL-1 receptor-related protein ST2 and induces T helper type 2-associated cytokines
-
Schmitz J, Owyang A, Oldham E, Song Y, Murphy E, McClanahan TK, Zurawski G, Moshrefi M, Qin J, Li X et al. (2005) IL-33, an interleukin-1-like cytokine that signals via the IL-1 receptor-related protein ST2 and induces T helper type 2-associated cytokines. Immunity 23, 479–490.
-
(2005)
Immunity
, vol.23
, pp. 479-490
-
-
Schmitz, J.1
Owyang, A.2
Oldham, E.3
Song, Y.4
Murphy, E.5
McClanahan, T.K.6
Zurawski, G.7
Moshrefi, M.8
Qin, J.9
Li, X.10
-
83
-
-
49449111630
-
IL-33 exacerbates antigen-induced arthritis by activating mast cells
-
Xu D, Jiang HR, Kewin P, Li Y, Mu R, Fraser AR, Pitman N, Kurowska-Stolarska M, McKenzie AN, McInnes IB et al. (2008) IL-33 exacerbates antigen-induced arthritis by activating mast cells. Proc Natl Acad Sci USA 105, 10913–10918.
-
(2008)
Proc Natl Acad Sci USA
, vol.105
, pp. 10913-10918
-
-
Xu, D.1
Jiang, H.R.2
Kewin, P.3
Li, Y.4
Mu, R.5
Fraser, A.R.6
Pitman, N.7
Kurowska-Stolarska, M.8
McKenzie, A.N.9
McInnes, I.B.10
-
84
-
-
33745873727
-
A crucial role for interleukin (IL)-1 in the induction of IL-17-producing T cells that mediate autoimmune encephalomyelitis
-
Sutton C, Brereton C, Keogh B, Mills KH & Lavelle EC (2006) A crucial role for interleukin (IL)-1 in the induction of IL-17-producing T cells that mediate autoimmune encephalomyelitis. J Exp Med 203, 1685–1691.
-
(2006)
J Exp Med
, vol.203
, pp. 1685-1691
-
-
Sutton, C.1
Brereton, C.2
Keogh, B.3
Mills, K.H.4
Lavelle, E.C.5
-
85
-
-
84874206379
-
IL-1 family cytokines trigger sterile inflammatory disease
-
Lukens JR, Gross JM & Kanneganti TD (2012) IL-1 family cytokines trigger sterile inflammatory disease. Front Immunol 3, A315.
-
(2012)
Front Immunol
, vol.3
, pp. 2315
-
-
Lukens, J.R.1
Gross, J.M.2
Kanneganti, T.D.3
|