메뉴 건너뛰기




Volumn 109, Issue 5, 2012, Pages 1673-1678

IL-33 is processed into mature bioactive forms by neutrophil elastase and cathepsin G

Author keywords

Alveolar epithelium; Inflammatory protease; Innate immunity; Serine protease inhibitor

Indexed keywords

CATHEPSIN G; INTERLEUKIN 33; LEUKOCYTE ELASTASE; PROTEINASE;

EID: 84857134135     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1115884109     Document Type: Article
Times cited : (472)

References (45)
  • 1
    • 62649139025 scopus 로고    scopus 로고
    • Immunological and inflammatory functions of the interleukin-1 family
    • Dinarello CA (2009) Immunological and inflammatory functions of the interleukin-1 family. Annu Rev Immunol 27:519-550.
    • (2009) Annu Rev Immunol , vol.27 , pp. 519-550
    • Dinarello, C.A.1
  • 2
    • 75549091673 scopus 로고    scopus 로고
    • The IL-1 family: Regulators of immunity
    • Sims JE, Smith DE (2010) The IL-1 family: regulators of immunity. Nat Rev Immunol 10: 89-102.
    • (2010) Nat Rev Immunol , vol.10 , pp. 89-102
    • Sims, J.E.1    Smith, D.E.2
  • 3
    • 79953813107 scopus 로고    scopus 로고
    • Interleukin-1 in the pathogenesis and treatment of inflammatory diseases
    • Dinarello CA (2011) Interleukin-1 in the pathogenesis and treatment of inflammatory diseases. Blood 117:3720-3732.
    • (2011) Blood , vol.117 , pp. 3720-3732
    • Dinarello, C.A.1
  • 7
    • 53249093714 scopus 로고    scopus 로고
    • Molecular mimicry between IL-33 and KSHV for attachment to chromatin through the H2A-H2B acidic pocket
    • Roussel L, Erard M, Cayrol C, Girard JP (2008) Molecular mimicry between IL-33 and KSHV for attachment to chromatin through the H2A-H2B acidic pocket. EMBO Rep 9: 1006-1012.
    • (2008) EMBO Rep , vol.9 , pp. 1006-1012
    • Roussel, L.1    Erard, M.2    Cayrol, C.3    Girard, J.P.4
  • 8
    • 74049121313 scopus 로고    scopus 로고
    • IL-33: A tissue derived cytokine pathway involved in allergic inflammation and asthma
    • Smith DE (2010) IL-33: a tissue derived cytokine pathway involved in allergic inflammation and asthma. Clin Exp Allergy 40:200-208.
    • (2010) Clin Exp Allergy , vol.40 , pp. 200-208
    • Smith, D.E.1
  • 9
    • 75549087056 scopus 로고    scopus 로고
    • Disease-associated functions of IL-33: The new kid in the IL-1 family
    • Liew FY, Pitman NI, McInnes IB (2010) Disease-associated functions of IL-33: the new kid in the IL-1 family. Nat Rev Immunol 10:103-110.
    • (2010) Nat Rev Immunol , vol.10 , pp. 103-110
    • Liew, F.Y.1    Pitman, N.I.2    McInnes, I.B.3
  • 10
  • 11
    • 77957113600 scopus 로고    scopus 로고
    • A large-scale, consortium-based genomewide association study of asthma
    • GABRIEL Consortium
    • Moffatt MF, et al.; GABRIEL Consortium (2010) A large-scale, consortium-based genomewide association study of asthma. N Engl J Med 363:1211-1221.
    • (2010) N Engl J Med , vol.363 , pp. 1211-1221
    • Moffatt, M.F.1
  • 12
    • 49449111630 scopus 로고    scopus 로고
    • IL-33 exacerbates antigen-induced arthritis by activating mast cells
    • Xu D, et al. (2008) IL-33 exacerbates antigen-induced arthritis by activating mast cells. Proc Natl Acad Sci USA 105:10913-10918.
    • (2008) Proc Natl Acad Sci USA , vol.105 , pp. 10913-10918
    • Xu, D.1
  • 13
    • 61649117392 scopus 로고    scopus 로고
    • Inhibition of interleukin-33 signaling attenuates the severity of experimental arthritis
    • Palmer G, et al. (2009) Inhibition of interleukin-33 signaling attenuates the severity of experimental arthritis. Arthritis Rheum 60:738-749.
    • (2009) Arthritis Rheum , vol.60 , pp. 738-749
    • Palmer, G.1
  • 14
    • 77952324145 scopus 로고    scopus 로고
    • Epithelial-derived IL-33 and its receptor ST2 are dysregulated in ulcerative colitis and in experimental Th1/Th2 driven enteritis
    • Pastorelli L, et al. (2010) Epithelial-derived IL-33 and its receptor ST2 are dysregulated in ulcerative colitis and in experimental Th1/Th2 driven enteritis. Proc Natl Acad Sci USA 107:8017-8022.
    • (2010) Proc Natl Acad Sci USA , vol.107 , pp. 8017-8022
    • Pastorelli, L.1
  • 16
    • 69449106110 scopus 로고    scopus 로고
    • IL-1 family members and STAT activators induce cytokine production by Th2, Th17, and Th1 cells
    • Guo L, et al. (2009) IL-1 family members and STAT activators induce cytokine production by Th2, Th17, and Th1 cells. Proc Natl Acad Sci USA 106:13463-13468.
    • (2009) Proc Natl Acad Sci USA , vol.106 , pp. 13463-13468
    • Guo, L.1
  • 17
    • 75749122181 scopus 로고    scopus 로고
    • Innate production of T(H)2 cytokines by adipose tissue-associated c-Kit(+)Sca-1(+) lymphoid cells
    • Moro K, et al. (2010) Innate production of T(H)2 cytokines by adipose tissue-associated c-Kit(+)Sca-1(+) lymphoid cells. Nature 463:540-544.
    • (2010) Nature , vol.463 , pp. 540-544
    • Moro, K.1
  • 18
    • 77951817855 scopus 로고    scopus 로고
    • Nuocytes represent a new innate effector leukocyte that mediates type-2 immunity
    • Neill DR, et al. (2010) Nuocytes represent a new innate effector leukocyte that mediates type-2 immunity. Nature 464:1367-1370.
    • (2010) Nature , vol.464 , pp. 1367-1370
    • Neill, D.R.1
  • 19
    • 77954926597 scopus 로고    scopus 로고
    • Systemically dispersed innate IL-13-expressing cells in type 2 immunity
    • Price AE, et al. (2010) Systemically dispersed innate IL-13-expressing cells in type 2 immunity. Proc Natl Acad Sci USA 107:11489-11494.
    • (2010) Proc Natl Acad Sci USA , vol.107 , pp. 11489-11494
    • Price, A.E.1
  • 20
    • 79959380307 scopus 로고    scopus 로고
    • Innate lymphoid cells mediate influenza-induced airway hyperreactivity independently of adaptive immunity
    • Chang YJ, et al. (2011) Innate lymphoid cells mediate influenza-induced airway hyperreactivity independently of adaptive immunity. Nat Immunol 12:631-638.
    • (2011) Nat Immunol , vol.12 , pp. 631-638
    • Chang, Y.J.1
  • 21
    • 85027948313 scopus 로고    scopus 로고
    • Innate lymphoid cells promote lung-tissue homeostasis after infection with influenza virus
    • 10.1038/ni.2131
    • Monticelli LA, et al. (2011) Innate lymphoid cells promote lung-tissue homeostasis after infection with influenza virus. Nat Immunol 12:1045-1054 10.1038/ni.2131.
    • (2011) Nat Immunol , vol.12 , pp. 1045-1054
    • Monticelli, L.A.1
  • 22
    • 78649821588 scopus 로고    scopus 로고
    • IL-33 is a crucial amplifier of innate rather than acquired immunity
    • Oboki K, et al. (2010) IL-33 is a crucial amplifier of innate rather than acquired immunity. Proc Natl Acad Sci USA 107:18581-18586.
    • (2010) Proc Natl Acad Sci USA , vol.107 , pp. 18581-18586
    • Oboki, K.1
  • 23
    • 67049158193 scopus 로고    scopus 로고
    • The IL-1-like cytokine IL-33 is inactivated after maturation by caspase-1
    • Cayrol C, Girard JP (2009) The IL-1-like cytokine IL-33 is inactivated after maturation by caspase-1. Proc Natl Acad Sci USA 106:9021-9026.
    • (2009) Proc Natl Acad Sci USA , vol.106 , pp. 9021-9026
    • Cayrol, C.1    Girard, J.P.2
  • 24
    • 68249137289 scopus 로고    scopus 로고
    • Suppression of interleukin-33 bioactivity through proteolysis by apoptotic caspases
    • Lüthi AU, et al. (2009) Suppression of interleukin-33 bioactivity through proteolysis by apoptotic caspases. Immunity 31:84-98.
    • (2009) Immunity , vol.31 , pp. 84-98
    • Lüthi, A.U.1
  • 25
    • 67651053209 scopus 로고    scopus 로고
    • Interleukin-33 is biologically active independently of caspase-1 cleavage
    • Talabot-Ayer D, Lamacchia C, Gabay C, Palmer G (2009) Interleukin-33 is biologically active independently of caspase-1 cleavage. J Biol Chem 284:19420-19426.
    • (2009) J Biol Chem , vol.284 , pp. 19420-19426
    • Talabot-Ayer, D.1    Lamacchia, C.2    Gabay, C.3    Palmer, G.4
  • 26
    • 73949088791 scopus 로고    scopus 로고
    • Caspase 3 inactivates biologically active full length interleukin-33 as a classical cytokine but does not prohibit nuclear translocation
    • Ali S, Nguyen DQ, Falk W, Martin MU (2010) Caspase 3 inactivates biologically active full length interleukin-33 as a classical cytokine but does not prohibit nuclear translocation. Biochem Biophys Res Commun 391:1512-1516.
    • (2010) Biochem Biophys Res Commun , vol.391 , pp. 1512-1516
    • Ali, S.1    Nguyen, D.Q.2    Falk, W.3    Martin, M.U.4
  • 27
    • 53749093767 scopus 로고    scopus 로고
    • The IL-1-like cytokine IL-33 is constitutively expressed in the nucleus of endothelial cells and epithelial cells in vivo: A novel 'alarmin'?
    • Moussion C, Ortega N, Girard JP (2008) The IL-1-like cytokine IL-33 is constitutively expressed in the nucleus of endothelial cells and epithelial cells in vivo: a novel 'alarmin'? PLoS ONE 3:e3331.
    • (2008) PLoS ONE , vol.3
    • Moussion, C.1    Ortega, N.2    Girard, J.P.3
  • 28
    • 0037062934 scopus 로고    scopus 로고
    • Release of chromatin protein HMGB1 by necrotic cells triggers inflammation
    • DOI 10.1038/nature00858
    • Scaffidi P, Misteli T, Bianchi ME (2002) Release of chromatin protein HMGB1 by necrotic cells triggers inflammation. Nature 418:191-195. (Pubitemid 34773774)
    • (2002) Nature , vol.418 , Issue.6894 , pp. 191-195
    • Scaffidi, P.1    Misteli, T.2    Bianchi, M.E.3
  • 29
    • 34447116244 scopus 로고    scopus 로고
    • Identification of a key pathway required for the sterile inflammatory response triggered by dying cells
    • Chen CJ, et al. (2007) Identification of a key pathway required for the sterile inflammatory response triggered by dying cells. Nat Med 13:851-856.
    • (2007) Nat Med , vol.13 , pp. 851-856
    • Chen, C.J.1
  • 30
    • 33845951211 scopus 로고    scopus 로고
    • DAMPs, PAMPs and alarmins: All we need to know about danger
    • Bianchi ME (2007) DAMPs, PAMPs and alarmins: all we need to know about danger. J Leukoc Biol 81:1-5.
    • (2007) J Leukoc Biol , vol.81 , pp. 1-5
    • Bianchi, M.E.1
  • 31
    • 77249085646 scopus 로고    scopus 로고
    • Differential release of chromatin-bound IL-1alpha discriminates between necrotic and apoptotic cell death by the ability to induce sterile inflammation
    • Cohen I, et al. (2010) Differential release of chromatin-bound IL-1alpha discriminates between necrotic and apoptotic cell death by the ability to induce sterile inflammation. Proc Natl Acad Sci USA 107:2574-2579.
    • (2010) Proc Natl Acad Sci USA , vol.107 , pp. 2574-2579
    • Cohen, I.1
  • 32
    • 80555133279 scopus 로고    scopus 로고
    • IL-1α and IL-1β recruit different myeloid cells and promote different stages of sterile inflammation
    • Rider P, et al. (2011) IL-1α and IL-1β recruit different myeloid cells and promote different stages of sterile inflammation. J Immunol 187:4835-4843.
    • (2011) J Immunol , vol.187 , pp. 4835-4843
    • Rider, P.1
  • 33
    • 33745559712 scopus 로고    scopus 로고
    • Neutrophil serine proteases: Specific regulators of inflammation
    • Pham CT (2006) Neutrophil serine proteases: specific regulators of inflammation. Nat Rev Immunol 6:541-550.
    • (2006) Nat Rev Immunol , vol.6 , pp. 541-550
    • Pham, C.T.1
  • 36
    • 73249139175 scopus 로고    scopus 로고
    • Caspase 1-independent activation of interleukin-1beta in neutrophil-predominant inflammation
    • Guma M, et al. (2009) Caspase 1-independent activation of interleukin-1beta in neutrophil-predominant inflammation. Arthritis Rheum 60:3642-3650.
    • (2009) Arthritis Rheum , vol.60 , pp. 3642-3650
    • Guma, M.1
  • 37
    • 73249144903 scopus 로고    scopus 로고
    • Inflammatory arthritis in caspase 1 gene-deficient mice: Contribution of proteinase 3 to caspase 1-independent production of bioactive interleukin- 1beta
    • Joosten LA, et al. (2009) Inflammatory arthritis in caspase 1 gene-deficient mice: contribution of proteinase 3 to caspase 1-independent production of bioactive interleukin- 1beta. Arthritis Rheum 60:3651-3662.
    • (2009) Arthritis Rheum , vol.60 , pp. 3651-3662
    • Joosten, L.A.1
  • 38
    • 77955053656 scopus 로고    scopus 로고
    • KU812 cells provide a novel in vitro model of the human IL-33/ ST2L axis: Functional responses and identification of signaling pathways
    • Tare N, et al. (2010) KU812 cells provide a novel in vitro model of the human IL-33/ ST2L axis: functional responses and identification of signaling pathways. Exp Cell Res 316:2527-2537.
    • (2010) Exp Cell Res , vol.316 , pp. 2527-2537
    • Tare, N.1
  • 40
    • 79955509396 scopus 로고    scopus 로고
    • Endogenous IL-33 enhances Th2 cytokine production and T-cell responses during allergic airway inflammation
    • Louten J, et al. (2011) Endogenous IL-33 enhances Th2 cytokine production and T-cell responses during allergic airway inflammation. Int Immunol 23:307-315.
    • (2011) Int Immunol , vol.23 , pp. 307-315
    • Louten, J.1
  • 41
    • 77956024623 scopus 로고    scopus 로고
    • IL-33 induces neutrophil migration in rheumatoid arthritis and is a target of anti-TNF therapy
    • Verri WA, Jr., et al. (2010) IL-33 induces neutrophil migration in rheumatoid arthritis and is a target of anti-TNF therapy. Ann Rheum Dis 69:1697-1703.
    • (2010) Ann Rheum Dis , vol.69 , pp. 1697-1703
    • Verri Jr., W.A.1
  • 44
    • 82455175456 scopus 로고    scopus 로고
    • Granzyme B-dependent proteolysis acts as a switch to enhance the proinflammatory activity of IL-1α
    • Afonina IS, et al. (2011) Granzyme B-dependent proteolysis acts as a switch to enhance the proinflammatory activity of IL-1α. Mol Cell 44:265-278.
    • (2011) Mol Cell , vol.44 , pp. 265-278
    • Afonina, I.S.1
  • 45
    • 67651033208 scopus 로고    scopus 로고
    • Mature interleukin-33 is produced by calpain-mediated cleavage in vivo
    • Hayakawa M, et al. (2009) Mature interleukin-33 is produced by calpain-mediated cleavage in vivo. Biochem Biophys Res Commun 387:218-222.
    • (2009) Biochem Biophys Res Commun , vol.387 , pp. 218-222
    • Hayakawa, M.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.