-
1
-
-
77951681958
-
Cytotoxic and non-cytotoxic roles of the CTL/NK protease granzyme B
-
Afonina I.S., Cullen S.P., Martin S.J. Cytotoxic and non-cytotoxic roles of the CTL/NK protease granzyme B. Immunol. Rev. 2010, 235:105-116.
-
(2010)
Immunol. Rev.
, vol.235
, pp. 105-116
-
-
Afonina, I.S.1
Cullen, S.P.2
Martin, S.J.3
-
2
-
-
82455175456
-
Granzyme B-dependent proteolysis acts as a switch to enhance the proinflammatory activity of IL-1α
-
Afonina I.S., Tynan G.A., Logue S.E., Cullen S.P., Bots M., Lüthi A.U., Reeves E.P., McElvaney N.G., Medema J.P., Lavelle E.C., Martin S.J. Granzyme B-dependent proteolysis acts as a switch to enhance the proinflammatory activity of IL-1α. Mol. Cell 2011, 44:265-278.
-
(2011)
Mol. Cell
, vol.44
, pp. 265-278
-
-
Afonina, I.S.1
Tynan, G.A.2
Logue, S.E.3
Cullen, S.P.4
Bots, M.5
Lüthi, A.U.6
Reeves, E.P.7
McElvaney, N.G.8
Medema, J.P.9
Lavelle, E.C.10
Martin, S.J.11
-
3
-
-
0036745064
-
Association of mutations in the NALP3/CIAS1/PYPAF1 gene with a broad phenotype including recurrent fever, cold sensitivity, sensorineural deafness, and AA amyloidosis
-
Aganna E., Martinon F., Hawkins P.N., Ross J.B., Swan D.C., Booth D.R., Lachmann H.J., Bybee A., Gaudet R., Woo P., et al. Association of mutations in the NALP3/CIAS1/PYPAF1 gene with a broad phenotype including recurrent fever, cold sensitivity, sensorineural deafness, and AA amyloidosis. Arthritis Rheum. 2002, 46:2445-2452.
-
(2002)
Arthritis Rheum.
, vol.46
, pp. 2445-2452
-
-
Aganna, E.1
Martinon, F.2
Hawkins, P.N.3
Ross, J.B.4
Swan, D.C.5
Booth, D.R.6
Lachmann, H.J.7
Bybee, A.8
Gaudet, R.9
Woo, P.10
-
4
-
-
1642285783
-
NALP3 forms an IL-1beta-processing inflammasome with increased activity in Muckle-Wells autoinflammatory disorder
-
Agostini L., Martinon F., Burns K., McDermott M.F., Hawkins P.N., Tschopp J. NALP3 forms an IL-1beta-processing inflammasome with increased activity in Muckle-Wells autoinflammatory disorder. Immunity 2004, 20:319-325.
-
(2004)
Immunity
, vol.20
, pp. 319-325
-
-
Agostini, L.1
Martinon, F.2
Burns, K.3
McDermott, M.F.4
Hawkins, P.N.5
Tschopp, J.6
-
5
-
-
84896736292
-
CD8+ Tcell granzyme B activates keratinocyte endogenous IL-18
-
Akeda T., Yamanaka K., Tsuda K., Omoto Y., Gabazza E.C., Mizutani H. CD8+ Tcell granzyme B activates keratinocyte endogenous IL-18. Arch. Dermatol. Res. 2014, 306:125-130.
-
(2014)
Arch. Dermatol. Res.
, vol.306
, pp. 125-130
-
-
Akeda, T.1
Yamanaka, K.2
Tsuda, K.3
Omoto, Y.4
Gabazza, E.C.5
Mizutani, H.6
-
6
-
-
73949088791
-
Caspase 3 inactivates biologically active full length interleukin-33 as a classical cytokine but does not prohibit nuclear translocation
-
Ali S., Nguyen D.Q., Falk W., Martin M.U. Caspase 3 inactivates biologically active full length interleukin-33 as a classical cytokine but does not prohibit nuclear translocation. Biochem. Biophys. Res. Commun. 2010, 391:1512-1516.
-
(2010)
Biochem. Biophys. Res. Commun.
, vol.391
, pp. 1512-1516
-
-
Ali, S.1
Nguyen, D.Q.2
Falk, W.3
Martin, M.U.4
-
7
-
-
80051926552
-
The dual function cytokine IL-33 interacts with the transcription factor NF-κB to dampen NF-κB-stimulated gene transcription
-
Ali S., Mohs A., Thomas M., Klare J., Ross R., Schmitz M.L., Martin M.U. The dual function cytokine IL-33 interacts with the transcription factor NF-κB to dampen NF-κB-stimulated gene transcription. J.Immunol. 2011, 187:1609-1616.
-
(2011)
J.Immunol.
, vol.187
, pp. 1609-1616
-
-
Ali, S.1
Mohs, A.2
Thomas, M.3
Klare, J.4
Ross, R.5
Schmitz, M.L.6
Martin, M.U.7
-
8
-
-
80054700818
-
Activated MCTC mast cells infiltrate diseased lung areas in cystic fibrosis and idiopathic pulmonary fibrosis
-
Andersson C.K., Andersson-Sjöland A., Mori M., Hallgren O., Pardo A., Eriksson L., Bjermer L., Löfdahl C.G., Selman M., Westergren-Thorsson G., Erjefält J.S. Activated MCTC mast cells infiltrate diseased lung areas in cystic fibrosis and idiopathic pulmonary fibrosis. Respir. Res. 2011, 12:139.
-
(2011)
Respir. Res.
, vol.12
, pp. 139
-
-
Andersson, C.K.1
Andersson-Sjöland, A.2
Mori, M.3
Hallgren, O.4
Pardo, A.5
Eriksson, L.6
Bjermer, L.7
Löfdahl, C.G.8
Selman, M.9
Westergren-Thorsson, G.10
Erjefält, J.S.11
-
9
-
-
84885966098
-
Proapoptotic chemotherapeutic drugs induce noncanonical processing and release of IL-1β via caspase-8 in dendritic cells
-
Antonopoulos C., El Sanadi C., Kaiser W.J., Mocarski E.S., Dubyak G.R. Proapoptotic chemotherapeutic drugs induce noncanonical processing and release of IL-1β via caspase-8 in dendritic cells. J.Immunol. 2013, 191:4789-4803.
-
(2013)
J.Immunol.
, vol.191
, pp. 4789-4803
-
-
Antonopoulos, C.1
El Sanadi, C.2
Kaiser, W.J.3
Mocarski, E.S.4
Dubyak, G.R.5
-
10
-
-
0000814155
-
Nucleotide sequence of human monocyte interleukin 1 precursor cDNA
-
Auron P.E., Webb A.C., Rosenwasser L.J., Mucci S.F., Rich A., Wolff S.M., Dinarello C.A. Nucleotide sequence of human monocyte interleukin 1 precursor cDNA. Proc. Natl. Acad. Sci. USA 1984, 81:7907-7911.
-
(1984)
Proc. Natl. Acad. Sci. USA
, vol.81
, pp. 7907-7911
-
-
Auron, P.E.1
Webb, A.C.2
Rosenwasser, L.J.3
Mucci, S.F.4
Rich, A.5
Wolff, S.M.6
Dinarello, C.A.7
-
11
-
-
84863268229
-
Contradictory functions (activation/termination) of neutrophil proteinase 3 enzyme (PR3) in interleukin-33 biological activity
-
Bae S., Kang T., Hong J., Lee S., Choi J., Jhun H., Kwak A., Hong K., Kim E., Jo S., Kim S. Contradictory functions (activation/termination) of neutrophil proteinase 3 enzyme (PR3) in interleukin-33 biological activity. J.Biol. Chem. 2012, 287:8205-8213.
-
(2012)
J.Biol. Chem.
, vol.287
, pp. 8205-8213
-
-
Bae, S.1
Kang, T.2
Hong, J.3
Lee, S.4
Choi, J.5
Jhun, H.6
Kwak, A.7
Hong, K.8
Kim, E.9
Jo, S.10
Kim, S.11
-
12
-
-
79957571971
-
IL-33-activated dendritic cells are critical for allergic airway inflammation
-
Besnard A.G., Togbe D., Guillou N., Erard F., Quesniaux V., Ryffel B. IL-33-activated dendritic cells are critical for allergic airway inflammation. Eur. J. Immunol. 2011, 41:1675-1686.
-
(2011)
Eur. J. Immunol.
, vol.41
, pp. 1675-1686
-
-
Besnard, A.G.1
Togbe, D.2
Guillou, N.3
Erard, F.4
Quesniaux, V.5
Ryffel, B.6
-
13
-
-
84922404569
-
Altered subcellular localization of IL-33 leads to non-resolving lethal inflammation
-
Bessa J., Meyer C.A., de Vera Mudry M.C., Schlicht S., Smith S.H., Iglesias A., Cote-Sierra J. Altered subcellular localization of IL-33 leads to non-resolving lethal inflammation. J.Autoimmun. 2014, 55:33-41.
-
(2014)
J.Autoimmun.
, vol.55
, pp. 33-41
-
-
Bessa, J.1
Meyer, C.A.2
de Vera Mudry, M.C.3
Schlicht, S.4
Smith, S.H.5
Iglesias, A.6
Cote-Sierra, J.7
-
14
-
-
0023947763
-
Generation of biologically active interleukin-1 beta by proteolytic cleavage of the inactive precursor
-
Black R.A., Kronheim S.R., Cantrell M., Deeley M.C., March C.J., Prickett K.S., Wignall J., Conlon P.J., Cosman D., Hopp T.P., et al. Generation of biologically active interleukin-1 beta by proteolytic cleavage of the inactive precursor. J.Biol. Chem. 1988, 263:9437-9442.
-
(1988)
J.Biol. Chem.
, vol.263
, pp. 9437-9442
-
-
Black, R.A.1
Kronheim, S.R.2
Cantrell, M.3
Deeley, M.C.4
March, C.J.5
Prickett, K.S.6
Wignall, J.7
Conlon, P.J.8
Cosman, D.9
Hopp, T.P.10
-
15
-
-
35748940015
-
Opposing activities of two novel members of the IL-1 ligand family regulate skin inflammation
-
Blumberg H., Dinh H., Trueblood E.S., Pretorius J., Kugler D., Weng N., Kanaly S.T., Towne J.E., Willis C.R., Kuechle M.K., et al. Opposing activities of two novel members of the IL-1 ligand family regulate skin inflammation. J.Exp. Med. 2007, 204:2603-2614.
-
(2007)
J.Exp. Med.
, vol.204
, pp. 2603-2614
-
-
Blumberg, H.1
Dinh, H.2
Trueblood, E.S.3
Pretorius, J.4
Kugler, D.5
Weng, N.6
Kanaly, S.T.7
Towne, J.E.8
Willis, C.R.9
Kuechle, M.K.10
-
16
-
-
84871125002
-
Cutting edge: FAS (CD95) mediates noncanonical IL-1β and IL-18 maturation via caspase-8 in an RIP3-independent manner
-
Bossaller L., Chiang P.I., Schmidt-Lauber C., Ganesan S., Kaiser W.J., Rathinam V.A., Mocarski E.S., Subramanian D., Green D.R., Silverman N., et al. Cutting edge: FAS (CD95) mediates noncanonical IL-1β and IL-18 maturation via caspase-8 in an RIP3-independent manner. J.Immunol. 2012, 189:5508-5512.
-
(2012)
J.Immunol.
, vol.189
, pp. 5508-5512
-
-
Bossaller, L.1
Chiang, P.I.2
Schmidt-Lauber, C.3
Ganesan, S.4
Kaiser, W.J.5
Rathinam, V.A.6
Mocarski, E.S.7
Subramanian, D.8
Green, D.R.9
Silverman, N.10
-
17
-
-
84894344719
-
Role of caspase-1 in nuclear translocation of IL-37, release of the cytokine, and IL-37 inhibition of innate immune responses
-
Bulau A.M., Nold M.F., Li S., Nold-Petry C.A., Fink M., Mansell A., Schwerd T., Hong J., Rubartelli A., Dinarello C.A., Bufler P. Role of caspase-1 in nuclear translocation of IL-37, release of the cytokine, and IL-37 inhibition of innate immune responses. Proc. Natl. Acad. Sci. USA 2014, 111:2650-2655.
-
(2014)
Proc. Natl. Acad. Sci. USA
, vol.111
, pp. 2650-2655
-
-
Bulau, A.M.1
Nold, M.F.2
Li, S.3
Nold-Petry, C.A.4
Fink, M.5
Mansell, A.6
Schwerd, T.7
Hong, J.8
Rubartelli, A.9
Dinarello, C.A.10
Bufler, P.11
-
18
-
-
33846101552
-
IL-33, the IL-1-like cytokine ligand for ST2 receptor, is a chromatin-associated nuclear factor invivo
-
Carriere V., Roussel L., Ortega N., Lacorre D.A., Americh L., Aguilar L., Bouche G., Girard J.P. IL-33, the IL-1-like cytokine ligand for ST2 receptor, is a chromatin-associated nuclear factor invivo. Proc. Natl. Acad. Sci. USA 2007, 104:282-287.
-
(2007)
Proc. Natl. Acad. Sci. USA
, vol.104
, pp. 282-287
-
-
Carriere, V.1
Roussel, L.2
Ortega, N.3
Lacorre, D.A.4
Americh, L.5
Aguilar, L.6
Bouche, G.7
Girard, J.P.8
-
19
-
-
0025871386
-
Involvement of a calpain-like protease in the processing of the murine interleukin 1 alpha precursor
-
Carruth L.M., Demczuk S., Mizel S.B. Involvement of a calpain-like protease in the processing of the murine interleukin 1 alpha precursor. J.Biol. Chem. 1991, 266:12162-12167.
-
(1991)
J.Biol. Chem.
, vol.266
, pp. 12162-12167
-
-
Carruth, L.M.1
Demczuk, S.2
Mizel, S.B.3
-
20
-
-
67049158193
-
The IL-1-like cytokine IL-33 is inactivated after maturation by caspase-1
-
Cayrol C., Girard J.P. The IL-1-like cytokine IL-33 is inactivated after maturation by caspase-1. Proc. Natl. Acad. Sci. USA 2009, 106:9021-9026.
-
(2009)
Proc. Natl. Acad. Sci. USA
, vol.106
, pp. 9021-9026
-
-
Cayrol, C.1
Girard, J.P.2
-
21
-
-
34447116244
-
Identification of a key pathway required for the sterile inflammatory response triggered by dying cells
-
Chen C.J., Kono H., Golenbock D., Reed G., Akira S., Rock K.L. Identification of a key pathway required for the sterile inflammatory response triggered by dying cells. Nat. Med. 2007, 13:851-856.
-
(2007)
Nat. Med.
, vol.13
, pp. 851-856
-
-
Chen, C.J.1
Kono, H.2
Golenbock, D.3
Reed, G.4
Akira, S.5
Rock, K.L.6
-
22
-
-
84885922086
-
Interleukin newcomers creating new numbers in rheumatology: IL-34 to IL-38
-
Clavel G., Thiolat A., Boissier M.C. Interleukin newcomers creating new numbers in rheumatology: IL-34 to IL-38. Joint Bone Spine 2013, 80:449-453.
-
(2013)
Joint Bone Spine
, vol.80
, pp. 449-453
-
-
Clavel, G.1
Thiolat, A.2
Boissier, M.C.3
-
23
-
-
0032989434
-
Converting enzyme-independent release of tumor necrosis factor alpha and IL-1beta from a stimulated human monocytic cell line in the presence of activated neutrophils or purified proteinase 3
-
Coeshott C., Ohnemus C., Pilyavskaya A., Ross S., Wieczorek M., Kroona H., Leimer A.H., Cheronis J. Converting enzyme-independent release of tumor necrosis factor alpha and IL-1beta from a stimulated human monocytic cell line in the presence of activated neutrophils or purified proteinase 3. Proc. Natl. Acad. Sci. USA 1999, 96:6261-6266.
-
(1999)
Proc. Natl. Acad. Sci. USA
, vol.96
, pp. 6261-6266
-
-
Coeshott, C.1
Ohnemus, C.2
Pilyavskaya, A.3
Ross, S.4
Wieczorek, M.5
Kroona, H.6
Leimer, A.H.7
Cheronis, J.8
-
24
-
-
77249085646
-
Differential release of chromatin-bound IL-1alpha discriminates between necrotic and apoptotic cell death by the ability to induce sterile inflammation
-
Cohen I., Rider P., Carmi Y., Braiman A., Dotan S., White M.R., Voronov E., Martin M.U., Dinarello C.A., Apte R.N. Differential release of chromatin-bound IL-1alpha discriminates between necrotic and apoptotic cell death by the ability to induce sterile inflammation. Proc. Natl. Acad. Sci. USA 2010, 107:2574-2579.
-
(2010)
Proc. Natl. Acad. Sci. USA
, vol.107
, pp. 2574-2579
-
-
Cohen, I.1
Rider, P.2
Carmi, Y.3
Braiman, A.4
Dotan, S.5
White, M.R.6
Voronov, E.7
Martin, M.U.8
Dinarello, C.A.9
Apte, R.N.10
-
25
-
-
84924415042
-
A small-molecule inhibitor of the NLRP3 inflammasome for the treatment of inflammatory diseases
-
Coll R.C., Robertson A.A., Chae J.J., Higgins S.C., Muñoz-Planillo R., Inserra M.C., Vetter I., Dungan L.S., Monks B.G., Stutz A., et al. A small-molecule inhibitor of the NLRP3 inflammasome for the treatment of inflammatory diseases. Nat. Med. 2015, 21:248-255.
-
(2015)
Nat. Med.
, vol.21
, pp. 248-255
-
-
Coll, R.C.1
Robertson, A.A.2
Chae, J.J.3
Higgins, S.C.4
Muñoz-Planillo, R.5
Inserra, M.C.6
Vetter, I.7
Dungan, L.S.8
Monks, B.G.9
Stutz, A.10
-
26
-
-
0034456694
-
Human keratinocytes are major producers of IL-18: predominant expression of the unprocessed form
-
Companjen A.R., van der Velden V.H., Vooys A., Debets R., Benner R., Prens E.P. Human keratinocytes are major producers of IL-18: predominant expression of the unprocessed form. Eur. Cytokine Netw. 2000, 11:383-390.
-
(2000)
Eur. Cytokine Netw.
, vol.11
, pp. 383-390
-
-
Companjen, A.R.1
van der Velden, V.H.2
Vooys, A.3
Debets, R.4
Benner, R.5
Prens, E.P.6
-
27
-
-
0037833742
-
Caspase-activation pathways in apoptosis and immunity
-
Creagh E.M., Conroy H., Martin S.J. Caspase-activation pathways in apoptosis and immunity. Immunol. Rev. 2003, 193:10-21.
-
(2003)
Immunol. Rev.
, vol.193
, pp. 10-21
-
-
Creagh, E.M.1
Conroy, H.2
Martin, S.J.3
-
28
-
-
38049103314
-
Mechanisms of granule-dependent killing
-
Cullen S.P., Martin S.J. Mechanisms of granule-dependent killing. Cell Death Differ. 2008, 15:251-262.
-
(2008)
Cell Death Differ.
, vol.15
, pp. 251-262
-
-
Cullen, S.P.1
Martin, S.J.2
-
29
-
-
62649139025
-
Immunological and inflammatory functions of the interleukin-1 family
-
Dinarello C.A. Immunological and inflammatory functions of the interleukin-1 family. Annu. Rev. Immunol. 2009, 27:519-550.
-
(2009)
Annu. Rev. Immunol.
, vol.27
, pp. 519-550
-
-
Dinarello, C.A.1
-
30
-
-
84866904408
-
Keep up the heat on IL-1
-
Dinarello C.A. Keep up the heat on IL-1. Blood 2012, 120:2538-2539.
-
(2012)
Blood
, vol.120
, pp. 2538-2539
-
-
Dinarello, C.A.1
-
31
-
-
0037679086
-
Interleukin 18 and interleukin 18 binding protein: possible role in immunosuppression of chronic renal failure
-
Dinarello C.A., Novick D., Rubinstein M., Lonnemann G. Interleukin 18 and interleukin 18 binding protein: possible role in immunosuppression of chronic renal failure. Blood Purif. 2003, 21:258-270.
-
(2003)
Blood Purif.
, vol.21
, pp. 258-270
-
-
Dinarello, C.A.1
Novick, D.2
Rubinstein, M.3
Lonnemann, G.4
-
32
-
-
84864545087
-
Treating inflammation by blocking interleukin-1 in a broad spectrum of diseases
-
Dinarello C.A., Simon A., van der Meer J.W. Treating inflammation by blocking interleukin-1 in a broad spectrum of diseases. Nat. Rev. Drug Discov. 2012, 11:633-652.
-
(2012)
Nat. Rev. Drug Discov.
, vol.11
, pp. 633-652
-
-
Dinarello, C.A.1
Simon, A.2
van der Meer, J.W.3
-
33
-
-
84929167350
-
Context-dependent role of IL-18 in cancer biology and counter-regulation by IL-18BP
-
Fabbi M., Carbotti G., Ferrini S. Context-dependent role of IL-18 in cancer biology and counter-regulation by IL-18BP. J.Leukoc. Biol. 2015, 97:665-675.
-
(2015)
J.Leukoc. Biol.
, vol.97
, pp. 665-675
-
-
Fabbi, M.1
Carbotti, G.2
Ferrini, S.3
-
34
-
-
79952447647
-
Chronic blockade of interleukin-1 (IL-1) prevents and attenuates neuropathic pain behavior and spontaneous ectopic neuronal activity following nerve injury
-
Gabay E., Wolf G., Shavit Y., Yirmiya R., Tal M. Chronic blockade of interleukin-1 (IL-1) prevents and attenuates neuropathic pain behavior and spontaneous ectopic neuronal activity following nerve injury. Eur. J. Pain 2011, 15:242-248.
-
(2011)
Eur. J. Pain
, vol.15
, pp. 242-248
-
-
Gabay, E.1
Wolf, G.2
Shavit, Y.3
Yirmiya, R.4
Tal, M.5
-
35
-
-
84890235827
-
The interleukin-1 family: back to the future
-
Garlanda C., Dinarello C.A., Mantovani A. The interleukin-1 family: back to the future. Immunity 2013, 39:1003-1018.
-
(2013)
Immunity
, vol.39
, pp. 1003-1018
-
-
Garlanda, C.1
Dinarello, C.A.2
Mantovani, A.3
-
36
-
-
34848875155
-
Pattern of interleukin-1beta secretion in response to lipopolysaccharide and ATP before and after interleukin-1 blockade in patients with CIAS1 mutations
-
Gattorno M., Tassi S., Carta S., Delfino L., Ferlito F., Pelagatti M.A., D'Osualdo A., Buoncompagni A., Alpigiani M.G., Alessio M., et al. Pattern of interleukin-1beta secretion in response to lipopolysaccharide and ATP before and after interleukin-1 blockade in patients with CIAS1 mutations. Arthritis Rheum. 2007, 56:3138-3148.
-
(2007)
Arthritis Rheum.
, vol.56
, pp. 3138-3148
-
-
Gattorno, M.1
Tassi, S.2
Carta, S.3
Delfino, L.4
Ferlito, F.5
Pelagatti, M.A.6
D'Osualdo, A.7
Buoncompagni, A.8
Alpigiani, M.G.9
Alessio, M.10
-
37
-
-
0031004174
-
Caspase-1 processes IFN-gamma-inducing factor and regulates LPS-induced IFN-gamma production
-
Ghayur T., Banerjee S., Hugunin M., Butler D., Herzog L., Carter A., Quintal L., Sekut L., Talanian R., Paskind M., et al. Caspase-1 processes IFN-gamma-inducing factor and regulates LPS-induced IFN-gamma production. Nature 1997, 386:619-623.
-
(1997)
Nature
, vol.386
, pp. 619-623
-
-
Ghayur, T.1
Banerjee, S.2
Hugunin, M.3
Butler, D.4
Herzog, L.5
Carter, A.6
Quintal, L.7
Sekut, L.8
Talanian, R.9
Paskind, M.10
-
38
-
-
7444272876
-
Proteomics-based identification of proteins interacting with Smad3: SREBP-2 forms a complex with Smad3 and inhibits its transcriptional activity
-
Grimsby S., Jaensson H., Dubrovska A., Lomnytska M., Hellman U., Souchelnytskyi S. Proteomics-based identification of proteins interacting with Smad3: SREBP-2 forms a complex with Smad3 and inhibits its transcriptional activity. FEBS Lett. 2004, 577:93-100.
-
(2004)
FEBS Lett.
, vol.577
, pp. 93-100
-
-
Grimsby, S.1
Jaensson, H.2
Dubrovska, A.3
Lomnytska, M.4
Hellman, U.5
Souchelnytskyi, S.6
-
39
-
-
84857175933
-
Dectin-1 is an extracellular pathogen sensor for the induction and processing of IL-1β via a noncanonical caspase-8 inflammasome
-
Gringhuis S.I., Kaptein T.M., Wevers B.A., Theelen B., van der Vlist M., Boekhout T., Geijtenbeek T.B. Dectin-1 is an extracellular pathogen sensor for the induction and processing of IL-1β via a noncanonical caspase-8 inflammasome. Nat. Immunol. 2012, 13:246-254.
-
(2012)
Nat. Immunol.
, vol.13
, pp. 246-254
-
-
Gringhuis, S.I.1
Kaptein, T.M.2
Wevers, B.A.3
Theelen, B.4
van der Vlist, M.5
Boekhout, T.6
Geijtenbeek, T.B.7
-
40
-
-
15644369352
-
Activation of interferon-gamma inducing factor mediated by interleukin-1beta converting enzyme
-
Gu Y., Kuida K., Tsutsui H., Ku G., Hsiao K., Fleming M.A., Hayashi N., Higashino K., Okamura H., Nakanishi K., et al. Activation of interferon-gamma inducing factor mediated by interleukin-1beta converting enzyme. Science 1997, 275:206-209.
-
(1997)
Science
, vol.275
, pp. 206-209
-
-
Gu, Y.1
Kuida, K.2
Tsutsui, H.3
Ku, G.4
Hsiao, K.5
Fleming, M.A.6
Hayashi, N.7
Higashino, K.8
Okamura, H.9
Nakanishi, K.10
-
41
-
-
73249139175
-
Caspase 1-independent activation of interleukin-1beta in neutrophil-predominant inflammation
-
Guma M., Ronacher L., Liu-Bryan R., Takai S., Karin M., Corr M. Caspase 1-independent activation of interleukin-1beta in neutrophil-predominant inflammation. Arthritis Rheum. 2009, 60:3642-3650.
-
(2009)
Arthritis Rheum.
, vol.60
, pp. 3642-3650
-
-
Guma, M.1
Ronacher, L.2
Liu-Bryan, R.3
Takai, S.4
Karin, M.5
Corr, M.6
-
42
-
-
84858775590
-
Lung natural helper cells are a critical source of Th2 cell-type cytokines in protease allergen-induced airway inflammation
-
Halim T.Y., Krauss R.H., Sun A.C., Takei F. Lung natural helper cells are a critical source of Th2 cell-type cytokines in protease allergen-induced airway inflammation. Immunity 2012, 36:451-463.
-
(2012)
Immunity
, vol.36
, pp. 451-463
-
-
Halim, T.Y.1
Krauss, R.H.2
Sun, A.C.3
Takei, F.4
-
43
-
-
84896343916
-
Group 2 innate lymphoid cells are critical for the initiation of adaptive T helper 2 cell-mediated allergic lung inflammation
-
Halim T.Y., Steer C.A., Mathä L., Gold M.J., Martinez-Gonzalez I., McNagny K.M., McKenzie A.N., Takei F. Group 2 innate lymphoid cells are critical for the initiation of adaptive T helper 2 cell-mediated allergic lung inflammation. Immunity 2014, 40:425-435.
-
(2014)
Immunity
, vol.40
, pp. 425-435
-
-
Halim, T.Y.1
Steer, C.A.2
Mathä, L.3
Gold, M.J.4
Martinez-Gonzalez, I.5
McNagny, K.M.6
McKenzie, A.N.7
Takei, F.8
-
44
-
-
79952535973
-
The cystic fibrosis neutrophil: a specialized yet potentially defective cell
-
Hayes E., Pohl K., McElvaney N.G., Reeves E.P. The cystic fibrosis neutrophil: a specialized yet potentially defective cell. Arch. Immunol. Ther. Exp. (Warsz.) 2011, 59:97-112.
-
(2011)
Arch. Immunol. Ther. Exp. (Warsz.)
, vol.59
, pp. 97-112
-
-
Hayes, E.1
Pohl, K.2
McElvaney, N.G.3
Reeves, E.P.4
-
45
-
-
0025220123
-
Processing of precursor interleukin 1 beta and inflammatory disease
-
Hazuda D.J., Strickler J., Kueppers F., Simon P.L., Young P.R. Processing of precursor interleukin 1 beta and inflammatory disease. J.Biol. Chem. 1990, 265:6318-6322.
-
(1990)
J.Biol. Chem.
, vol.265
, pp. 6318-6322
-
-
Hazuda, D.J.1
Strickler, J.2
Kueppers, F.3
Simon, P.L.4
Young, P.R.5
-
46
-
-
0025882834
-
Structure-function mapping of interleukin 1 precursors. Cleavage leads to a conformational change in the mature protein
-
Hazuda D.J., Strickler J., Simon P., Young P.R. Structure-function mapping of interleukin 1 precursors. Cleavage leads to a conformational change in the mature protein. J.Biol. Chem. 1991, 266:7081-7086.
-
(1991)
J.Biol. Chem.
, vol.266
, pp. 7081-7086
-
-
Hazuda, D.J.1
Strickler, J.2
Simon, P.3
Young, P.R.4
-
47
-
-
33744960322
-
Human keratinocytes acquire cellular cytotoxicity under UV-B irradiation. Implication of granzyme B and perforin
-
Hernandez-Pigeon H., Jean C., Charruyer A., Haure M.J., Titeux M., Tonasso L., Quillet-Mary A., Baudouin C., Charveron M., Laurent G. Human keratinocytes acquire cellular cytotoxicity under UV-B irradiation. Implication of granzyme B and perforin. J.Biol. Chem. 2006, 281:13525-13532.
-
(2006)
J.Biol. Chem.
, vol.281
, pp. 13525-13532
-
-
Hernandez-Pigeon, H.1
Jean, C.2
Charruyer, A.3
Haure, M.J.4
Titeux, M.5
Tonasso, L.6
Quillet-Mary, A.7
Baudouin, C.8
Charveron, M.9
Laurent, G.10
-
48
-
-
34247187374
-
UVA induces granzyme B in human keratinocytes through MIF: implication in extracellular matrix remodeling
-
Hernandez-Pigeon H., Jean C., Charruyer A., Haure M.J., Baudouin C., Charveron M., Quillet-Mary A., Laurent G. UVA induces granzyme B in human keratinocytes through MIF: implication in extracellular matrix remodeling. J.Biol. Chem. 2007, 282:8157-8164.
-
(2007)
J.Biol. Chem.
, vol.282
, pp. 8157-8164
-
-
Hernandez-Pigeon, H.1
Jean, C.2
Charruyer, A.3
Haure, M.J.4
Baudouin, C.5
Charveron, M.6
Quillet-Mary, A.7
Laurent, G.8
-
49
-
-
77953609646
-
Serine proteases of the human immune system in health and disease
-
Heutinck K.M., ten Berge I.J., Hack C.E., Hamann J., Rowshani A.T. Serine proteases of the human immune system in health and disease. Mol. Immunol. 2010, 47:1943-1955.
-
(2010)
Mol. Immunol.
, vol.47
, pp. 1943-1955
-
-
Heutinck, K.M.1
ten Berge, I.J.2
Hack, C.E.3
Hamann, J.4
Rowshani, A.T.5
-
50
-
-
0026048272
-
Interleukin 1 is processed and released during apoptosis
-
Hogquist K.A., Nett M.A., Unanue E.R., Chaplin D.D. Interleukin 1 is processed and released during apoptosis. Proc. Natl. Acad. Sci. USA 1991, 88:8485-8489.
-
(1991)
Proc. Natl. Acad. Sci. USA
, vol.88
, pp. 8485-8489
-
-
Hogquist, K.A.1
Nett, M.A.2
Unanue, E.R.3
Chaplin, D.D.4
-
51
-
-
0032482168
-
Production of mice deficient in genes for interleukin (IL)-1alpha, IL-1beta, IL-1alpha/beta, and IL-1 receptor antagonist shows that IL-1beta is crucial in turpentine-induced fever development and glucocorticoid secretion
-
Horai R., Asano M., Sudo K., Kanuka H., Suzuki M., Nishihara M., Takahashi M., Iwakura Y. Production of mice deficient in genes for interleukin (IL)-1alpha, IL-1beta, IL-1alpha/beta, and IL-1 receptor antagonist shows that IL-1beta is crucial in turpentine-induced fever development and glucocorticoid secretion. J.Exp. Med. 1998, 187:1463-1475.
-
(1998)
J.Exp. Med.
, vol.187
, pp. 1463-1475
-
-
Horai, R.1
Asano, M.2
Sudo, K.3
Kanuka, H.4
Suzuki, M.5
Nishihara, M.6
Takahashi, M.7
Iwakura, Y.8
-
52
-
-
0026336480
-
Probing the role of interleukin-1 beta convertase in interleukin-1 beta secretion
-
Howard A.D., Chartrain N., Ding G.F., Kostura M.J., Limjuco G., Schmidt J.A., Tocci M.J. Probing the role of interleukin-1 beta convertase in interleukin-1 beta secretion. Agents Actions Suppl. 1991, 35:77-83.
-
(1991)
Agents Actions Suppl.
, vol.35
, pp. 77-83
-
-
Howard, A.D.1
Chartrain, N.2
Ding, G.F.3
Kostura, M.J.4
Limjuco, G.5
Schmidt, J.A.6
Tocci, M.J.7
-
53
-
-
79951821248
-
IL-1F5, -F6, -F8, and -F9: a novel IL-1 family signaling system that is active in psoriasis and promotes keratinocyte antimicrobial peptide expression
-
Johnston A., Xing X., Guzman A.M., Riblett M., Loyd C.M., Ward N.L., Wohn C., Prens E.P., Wang F., Maier L.E., et al. IL-1F5, -F6, -F8, and -F9: a novel IL-1 family signaling system that is active in psoriasis and promotes keratinocyte antimicrobial peptide expression. J.Immunol. 2011, 186:2613-2622.
-
(2011)
J.Immunol.
, vol.186
, pp. 2613-2622
-
-
Johnston, A.1
Xing, X.2
Guzman, A.M.3
Riblett, M.4
Loyd, C.M.5
Ward, N.L.6
Wohn, C.7
Prens, E.P.8
Wang, F.9
Maier, L.E.10
-
54
-
-
73249144903
-
Inflammatory arthritis in caspase 1 gene-deficient mice: contribution of proteinase 3 to caspase 1-independent production of bioactive interleukin-1beta
-
Joosten L.A., Netea M.G., Fantuzzi G., Koenders M.I., Helsen M.M., Sparrer H., Pham C.T., van der Meer J.W., Dinarello C.A., van den Berg W.B. Inflammatory arthritis in caspase 1 gene-deficient mice: contribution of proteinase 3 to caspase 1-independent production of bioactive interleukin-1beta. Arthritis Rheum. 2009, 60:3651-3662.
-
(2009)
Arthritis Rheum.
, vol.60
, pp. 3651-3662
-
-
Joosten, L.A.1
Netea, M.G.2
Fantuzzi, G.3
Koenders, M.I.4
Helsen, M.M.5
Sparrer, H.6
Pham, C.T.7
van der Meer, J.W.8
Dinarello, C.A.9
van den Berg, W.B.10
-
55
-
-
0034192466
-
Dual role of caspase-11 in mediating activation of caspase-1 and caspase-3 under pathological conditions
-
Kang S.J., Wang S., Hara H., Peterson E.P., Namura S., Amin-Hanjani S., Huang Z., Srinivasan A., Tomaselli K.J., Thornberry N.A., et al. Dual role of caspase-11 in mediating activation of caspase-1 and caspase-3 under pathological conditions. J.Cell Biol. 2000, 149:613-622.
-
(2000)
J.Cell Biol.
, vol.149
, pp. 613-622
-
-
Kang, S.J.1
Wang, S.2
Hara, H.3
Peterson, E.P.4
Namura, S.5
Amin-Hanjani, S.6
Huang, Z.7
Srinivasan, A.8
Tomaselli, K.J.9
Thornberry, N.A.10
-
56
-
-
80455176839
-
Non-canonical inflammasome activation targets caspase-11
-
Kayagaki N., Warming S., Lamkanfi M., Vande Walle L., Louie S., Dong J., Newton K., Qu Y., Liu J., Heldens S., et al. Non-canonical inflammasome activation targets caspase-11. Nature 2011, 479:117-121.
-
(2011)
Nature
, vol.479
, pp. 117-121
-
-
Kayagaki, N.1
Warming, S.2
Lamkanfi, M.3
Vande Walle, L.4
Louie, S.5
Dong, J.6
Newton, K.7
Qu, Y.8
Liu, J.9
Heldens, S.10
-
57
-
-
0025182760
-
Identification of calcium-activated neutral protease as a processing enzyme of human interleukin 1 alpha
-
Kobayashi Y., Yamamoto K., Saido T., Kawasaki H., Oppenheim J.J., Matsushima K. Identification of calcium-activated neutral protease as a processing enzyme of human interleukin 1 alpha. Proc. Natl. Acad. Sci. USA 1990, 87:5548-5552.
-
(1990)
Proc. Natl. Acad. Sci. USA
, vol.87
, pp. 5548-5552
-
-
Kobayashi, Y.1
Yamamoto, K.2
Saido, T.3
Kawasaki, H.4
Oppenheim, J.J.5
Matsushima, K.6
-
58
-
-
0002928890
-
Identification of a monocyte specific pre-interleukin 1 beta convertase activity
-
Kostura M.J., Tocci M.J., Limjuco G., Chin J., Cameron P., Hillman A.G., Chartrain N.A., Schmidt J.A. Identification of a monocyte specific pre-interleukin 1 beta convertase activity. Proc. Natl. Acad. Sci. USA 1989, 86:5227-5231.
-
(1989)
Proc. Natl. Acad. Sci. USA
, vol.86
, pp. 5227-5231
-
-
Kostura, M.J.1
Tocci, M.J.2
Limjuco, G.3
Chin, J.4
Cameron, P.5
Hillman, A.G.6
Chartrain, N.A.7
Schmidt, J.A.8
-
59
-
-
0028920863
-
Altered cytokine export and apoptosis in mice deficient in interleukin-1 beta converting enzyme
-
Kuida K., Lippke J.A., Ku G., Harding M.W., Livingston D.J., Su M.S., Flavell R.A. Altered cytokine export and apoptosis in mice deficient in interleukin-1 beta converting enzyme. Science 1995, 267:2000-2003.
-
(1995)
Science
, vol.267
, pp. 2000-2003
-
-
Kuida, K.1
Lippke, J.A.2
Ku, G.3
Harding, M.W.4
Livingston, D.J.5
Su, M.S.6
Flavell, R.A.7
-
60
-
-
0036020218
-
Interleukin-1F7B (IL-1H4/IL-1F7) is processed by caspase-1 and mature IL-1F7B binds to the IL-18 receptor but does not induce IFN-gamma production
-
Kumar S., Hanning C.R., Brigham-Burke M.R., Rieman D.J., Lehr R., Khandekar S., Kirkpatrick R.B., Scott G.F., Lee J.C., Lynch F.J., et al. Interleukin-1F7B (IL-1H4/IL-1F7) is processed by caspase-1 and mature IL-1F7B binds to the IL-18 receptor but does not induce IFN-gamma production. Cytokine 2002, 18:61-71.
-
(2002)
Cytokine
, vol.18
, pp. 61-71
-
-
Kumar, S.1
Hanning, C.R.2
Brigham-Burke, M.R.3
Rieman, D.J.4
Lehr, R.5
Khandekar, S.6
Kirkpatrick, R.B.7
Scott, G.F.8
Lee, J.C.9
Lynch, F.J.10
-
61
-
-
0343474749
-
Identification of a membrane-associated interleukin 1 in macrophages
-
Kurt-Jones E.A., Beller D.I., Mizel S.B., Unanue E.R. Identification of a membrane-associated interleukin 1 in macrophages. Proc. Natl. Acad. Sci. USA 1985, 82:1204-1208.
-
(1985)
Proc. Natl. Acad. Sci. USA
, vol.82
, pp. 1204-1208
-
-
Kurt-Jones, E.A.1
Beller, D.I.2
Mizel, S.B.3
Unanue, E.R.4
-
62
-
-
0023199874
-
Membrane interleukin 1 induction on human endothelial cells and dermal fibroblasts
-
Kurt-Jones E.A., Fiers W., Pober J.S. Membrane interleukin 1 induction on human endothelial cells and dermal fibroblasts. J.Immunol. 1987, 139:2317-2324.
-
(1987)
J.Immunol.
, vol.139
, pp. 2317-2324
-
-
Kurt-Jones, E.A.1
Fiers, W.2
Pober, J.S.3
-
63
-
-
84901310586
-
Mechanisms and functions of inflammasomes
-
Lamkanfi M., Dixit V.M. Mechanisms and functions of inflammasomes. Cell 2014, 157:1013-1022.
-
(2014)
Cell
, vol.157
, pp. 1013-1022
-
-
Lamkanfi, M.1
Dixit, V.M.2
-
64
-
-
84857134135
-
IL-33 is processed into mature bioactive forms by neutrophil elastase and cathepsin G
-
Lefrançais E., Roga S., Gautier V., Gonzalez-de-Peredo A., Monsarrat B., Girard J.P., Cayrol C. IL-33 is processed into mature bioactive forms by neutrophil elastase and cathepsin G. Proc. Natl. Acad. Sci. USA 2012, 109:1673-1678.
-
(2012)
Proc. Natl. Acad. Sci. USA
, vol.109
, pp. 1673-1678
-
-
Lefrançais, E.1
Roga, S.2
Gautier, V.3
Gonzalez-de-Peredo, A.4
Monsarrat, B.5
Girard, J.P.6
Cayrol, C.7
-
65
-
-
0028984948
-
Mice deficient in IL-1 beta-converting enzyme are defective in production of mature IL-1 beta and resistant to endotoxic shock
-
Li P., Allen H., Banerjee S., Franklin S., Herzog L., Johnston C., McDowell J., Paskind M., Rodman L., Salfeld J., et al. Mice deficient in IL-1 beta-converting enzyme are defective in production of mature IL-1 beta and resistant to endotoxic shock. Cell 1995, 80:401-411.
-
(1995)
Cell
, vol.80
, pp. 401-411
-
-
Li, P.1
Allen, H.2
Banerjee, S.3
Franklin, S.4
Herzog, L.5
Johnston, C.6
McDowell, J.7
Paskind, M.8
Rodman, L.9
Salfeld, J.10
-
66
-
-
84923676031
-
Extracellular forms of IL-37 inhibit innate inflammation invitro and invivo but require the IL-1 family decoy receptor IL-1R8
-
Li S., Neff C.P., Barber K., Hong J., Luo Y., Azam T., Palmer B.E., Fujita M., Garlanda C., Mantovani A., et al. Extracellular forms of IL-37 inhibit innate inflammation invitro and invivo but require the IL-1 family decoy receptor IL-1R8. Proc. Natl. Acad. Sci. USA 2015, 112:2497-2502.
-
(2015)
Proc. Natl. Acad. Sci. USA
, vol.112
, pp. 2497-2502
-
-
Li, S.1
Neff, C.P.2
Barber, K.3
Hong, J.4
Luo, Y.5
Azam, T.6
Palmer, B.E.7
Fujita, M.8
Garlanda, C.9
Mantovani, A.10
-
67
-
-
0037108528
-
Pseudomonas aeruginosa activates human mast cells to induce neutrophil transendothelial migration via mast cell-derived IL-1 alpha and beta
-
Lin T.J., Garduno R., Boudreau R.T., Issekutz A.C. Pseudomonas aeruginosa activates human mast cells to induce neutrophil transendothelial migration via mast cell-derived IL-1 alpha and beta. J.Immunol. 2002, 169:4522-4530.
-
(2002)
J.Immunol.
, vol.169
, pp. 4522-4530
-
-
Lin, T.J.1
Garduno, R.2
Boudreau, R.T.3
Issekutz, A.C.4
-
68
-
-
84883815093
-
Structural insights into the interaction of IL-33 with its receptors
-
Liu X., Hammel M., He Y., Tainer J.A., Jeng U.S., Zhang L., Wang S., Wang X. Structural insights into the interaction of IL-33 with its receptors. Proc. Natl. Acad. Sci. USA 2013, 110:14918-14923.
-
(2013)
Proc. Natl. Acad. Sci. USA
, vol.110
, pp. 14918-14923
-
-
Liu, X.1
Hammel, M.2
He, Y.3
Tainer, J.A.4
Jeng, U.S.5
Zhang, L.6
Wang, S.7
Wang, X.8
-
69
-
-
84925776039
-
IL-37 requires IL-18Rα and SIGIRR/IL-1R8 to diminish allergic airway inflammation in mice
-
Lunding L., Webering S., Vock C., Schröder A., Raedler D., Schaub B., Fehrenbach H., Wegmann M. IL-37 requires IL-18Rα and SIGIRR/IL-1R8 to diminish allergic airway inflammation in mice. Allergy 2015, 70:366-373.
-
(2015)
Allergy
, vol.70
, pp. 366-373
-
-
Lunding, L.1
Webering, S.2
Vock, C.3
Schröder, A.4
Raedler, D.5
Schaub, B.6
Fehrenbach, H.7
Wegmann, M.8
-
70
-
-
68249137289
-
Suppression of interleukin-33 bioactivity through proteolysis by apoptotic caspases
-
Lüthi A.U., Cullen S.P., McNeela E.A., Duriez P.J., Afonina I.S., Sheridan C., Brumatti G., Taylor R.C., Kersse K., Vandenabeele P., et al. Suppression of interleukin-33 bioactivity through proteolysis by apoptotic caspases. Immunity 2009, 31:84-98.
-
(2009)
Immunity
, vol.31
, pp. 84-98
-
-
Lüthi, A.U.1
Cullen, S.P.2
McNeela, E.A.3
Duriez, P.J.4
Afonina, I.S.5
Sheridan, C.6
Brumatti, G.7
Taylor, R.C.8
Kersse, K.9
Vandenabeele, P.10
-
72
-
-
51049100571
-
Stimulation of Toll-like receptor 3 and 4 induces interleukin-1beta maturation by caspase-8
-
Maelfait J., Vercammen E., Janssens S., Schotte P., Haegman M., Magez S., Beyaert R. Stimulation of Toll-like receptor 3 and 4 induces interleukin-1beta maturation by caspase-8. J.Exp. Med. 2008, 205:1967-1973.
-
(2008)
J.Exp. Med.
, vol.205
, pp. 1967-1973
-
-
Maelfait, J.1
Vercammen, E.2
Janssens, S.3
Schotte, P.4
Haegman, M.5
Magez, S.6
Beyaert, R.7
-
73
-
-
0022364132
-
Cloning, sequence and expression of two distinct human interleukin-1 complementary DNAs
-
March C.J., Mosley B., Larsen A., Cerretti D.P., Braedt G., Price V., Gillis S., Henney C.S., Kronheim S.R., Grabstein K., et al. Cloning, sequence and expression of two distinct human interleukin-1 complementary DNAs. Nature 1985, 315:641-647.
-
(1985)
Nature
, vol.315
, pp. 641-647
-
-
March, C.J.1
Mosley, B.2
Larsen, A.3
Cerretti, D.P.4
Braedt, G.5
Price, V.6
Gillis, S.7
Henney, C.S.8
Kronheim, S.R.9
Grabstein, K.10
-
74
-
-
84860390352
-
Interleukin-36-receptor antagonist deficiency and generalized pustular psoriasis
-
Marrakchi S., Guigue P., Renshaw B.R., Puel A., Pei X.Y., Fraitag S., Zribi J., Bal E., Cluzeau C., Chrabieh M., et al. Interleukin-36-receptor antagonist deficiency and generalized pustular psoriasis. N.Engl. J. Med. 2011, 365:620-628.
-
(2011)
N.Engl. J. Med.
, vol.365
, pp. 620-628
-
-
Marrakchi, S.1
Guigue, P.2
Renshaw, B.R.3
Puel, A.4
Pei, X.Y.5
Fraitag, S.6
Zribi, J.7
Bal, E.8
Cluzeau, C.9
Chrabieh, M.10
-
75
-
-
84861435630
-
A perspective on mammalian caspases as positive and negative regulators of inflammation
-
Martin S.J., Henry C.M., Cullen S.P. A perspective on mammalian caspases as positive and negative regulators of inflammation. Mol. Cell 2012, 46:387-397.
-
(2012)
Mol. Cell
, vol.46
, pp. 387-397
-
-
Martin, S.J.1
Henry, C.M.2
Cullen, S.P.3
-
76
-
-
0022638421
-
Intracellular localization of human monocyte associated interleukin 1 (IL 1) activity and release of biologically active IL 1 from monocytes by trypsin and plasmin
-
Matsushima K., Taguchi M., Kovacs E.J., Young H.A., Oppenheim J.J. Intracellular localization of human monocyte associated interleukin 1 (IL 1) activity and release of biologically active IL 1 from monocytes by trypsin and plasmin. J.Immunol. 1986, 136:2883-2891.
-
(1986)
J.Immunol.
, vol.136
, pp. 2883-2891
-
-
Matsushima, K.1
Taguchi, M.2
Kovacs, E.J.3
Young, H.A.4
Oppenheim, J.J.5
-
77
-
-
80053624991
-
Interleukin 37 expression protects mice from colitis
-
McNamee E.N., Masterson J.C., Jedlicka P., McManus M., Grenz A., Collins C.B., Nold M.F., Nold-Petry C., Bufler P., Dinarello C.A., Rivera-Nieves J. Interleukin 37 expression protects mice from colitis. Proc. Natl. Acad. Sci. USA 2011, 108:16711-16716.
-
(2011)
Proc. Natl. Acad. Sci. USA
, vol.108
, pp. 16711-16716
-
-
McNamee, E.N.1
Masterson, J.C.2
Jedlicka, P.3
McManus, M.4
Grenz, A.5
Collins, C.B.6
Nold, M.F.7
Nold-Petry, C.8
Bufler, P.9
Dinarello, C.A.10
Rivera-Nieves, J.11
-
78
-
-
55349138368
-
Human and mouse granzyme A induce a proinflammatory cytokine response
-
Metkar S.S., Menaa C., Pardo J., Wang B., Wallich R., Freudenberg M., Kim S., Raja S.M., Shi L., Simon M.M., Froelich C.J. Human and mouse granzyme A induce a proinflammatory cytokine response. Immunity 2008, 29:720-733.
-
(2008)
Immunity
, vol.29
, pp. 720-733
-
-
Metkar, S.S.1
Menaa, C.2
Pardo, J.3
Wang, B.4
Wallich, R.5
Freudenberg, M.6
Kim, S.7
Raja, S.M.8
Shi, L.9
Simon, M.M.10
Froelich, C.J.11
-
79
-
-
0026040529
-
Rapid and specific conversion of precursor interleukin 1 beta (IL-1 beta) to an active IL-1 species by human mast cell chymase
-
Mizutani H., Schechter N., Lazarus G., Black R.A., Kupper T.S. Rapid and specific conversion of precursor interleukin 1 beta (IL-1 beta) to an active IL-1 species by human mast cell chymase. J.Exp. Med. 1991, 174:821-825.
-
(1991)
J.Exp. Med.
, vol.174
, pp. 821-825
-
-
Mizutani, H.1
Schechter, N.2
Lazarus, G.3
Black, R.A.4
Kupper, T.S.5
-
80
-
-
0023263620
-
Determination of the minimum polypeptide lengths of the functionally active sites of human interleukins 1 alpha and 1 beta
-
Mosley B., Dower S.K., Gillis S., Cosman D. Determination of the minimum polypeptide lengths of the functionally active sites of human interleukins 1 alpha and 1 beta. Proc. Natl. Acad. Sci. USA 1987, 84:4572-4576.
-
(1987)
Proc. Natl. Acad. Sci. USA
, vol.84
, pp. 4572-4576
-
-
Mosley, B.1
Dower, S.K.2
Gillis, S.3
Cosman, D.4
-
81
-
-
0023165175
-
The interleukin-1 receptor binds the human interleukin-1 alpha precursor but not the interleukin-1 beta precursor
-
Mosley B., Urdal D.L., Prickett K.S., Larsen A., Cosman D., Conlon P.J., Gillis S., Dower S.K. The interleukin-1 receptor binds the human interleukin-1 alpha precursor but not the interleukin-1 beta precursor. J.Biol. Chem. 1987, 262:2941-2944.
-
(1987)
J.Biol. Chem.
, vol.262
, pp. 2941-2944
-
-
Mosley, B.1
Urdal, D.L.2
Prickett, K.S.3
Larsen, A.4
Cosman, D.5
Conlon, P.J.6
Gillis, S.7
Dower, S.K.8
-
82
-
-
33745009509
-
Deficiency of interleukin-18 in mice leads to hyperphagia, obesity and insulin resistance
-
Netea M.G., Joosten L.A., Lewis E., Jensen D.R., Voshol P.J., Kullberg B.J., Tack C.J., van Krieken H., Kim S.H., Stalenhoef A.F., et al. Deficiency of interleukin-18 in mice leads to hyperphagia, obesity and insulin resistance. Nat. Med. 2006, 12:650-656.
-
(2006)
Nat. Med.
, vol.12
, pp. 650-656
-
-
Netea, M.G.1
Joosten, L.A.2
Lewis, E.3
Jensen, D.R.4
Voshol, P.J.5
Kullberg, B.J.6
Tack, C.J.7
van Krieken, H.8
Kim, S.H.9
Stalenhoef, A.F.10
-
83
-
-
0347364681
-
Membrane-associated IL-1 contributes to chronic synovitis and cartilage destruction in human IL-1 alpha transgenic mice
-
Niki Y., Yamada H., Kikuchi T., Toyama Y., Matsumoto H., Fujikawa K., Tada N. Membrane-associated IL-1 contributes to chronic synovitis and cartilage destruction in human IL-1 alpha transgenic mice. J.Immunol. 2004, 172:577-584.
-
(2004)
J.Immunol.
, vol.172
, pp. 577-584
-
-
Niki, Y.1
Yamada, H.2
Kikuchi, T.3
Toyama, Y.4
Matsumoto, H.5
Fujikawa, K.6
Tada, N.7
-
84
-
-
77958149102
-
IL-37 is a fundamental inhibitor of innate immunity
-
Nold M.F., Nold-Petry C.A., Zepp J.A., Palmer B.E., Bufler P., Dinarello C.A. IL-37 is a fundamental inhibitor of innate immunity. Nat. Immunol. 2010, 11:1014-1022.
-
(2010)
Nat. Immunol.
, vol.11
, pp. 1014-1022
-
-
Nold, M.F.1
Nold-Petry, C.A.2
Zepp, J.A.3
Palmer, B.E.4
Bufler, P.5
Dinarello, C.A.6
-
85
-
-
84925671141
-
IL-37 requires the receptors IL-18Rα and IL-1R8 (SIGIRR) to carry out its multifaceted anti-inflammatory program upon innate signal transduction
-
Nold-Petry C.A., Lo C.Y., Rudloff I., Elgass K.D., Li S., Gantier M.P., Lotz-Havla A.S., Gersting S.W., Cho S.X., Lao J.C., et al. IL-37 requires the receptors IL-18Rα and IL-1R8 (SIGIRR) to carry out its multifaceted anti-inflammatory program upon innate signal transduction. Nat. Immunol. 2015, 16:354-365.
-
(2015)
Nat. Immunol.
, vol.16
, pp. 354-365
-
-
Nold-Petry, C.A.1
Lo, C.Y.2
Rudloff, I.3
Elgass, K.D.4
Li, S.5
Gantier, M.P.6
Lotz-Havla, A.S.7
Gersting, S.W.8
Cho, S.X.9
Lao, J.C.10
-
86
-
-
84892867717
-
Interleukin-18, more than a Th1 cytokine
-
Novick D., Kim S., Kaplanski G., Dinarello C.A. Interleukin-18, more than a Th1 cytokine. Semin. Immunol. 2013, 25:439-448.
-
(2013)
Semin. Immunol.
, vol.25
, pp. 439-448
-
-
Novick, D.1
Kim, S.2
Kaplanski, G.3
Dinarello, C.A.4
-
87
-
-
77954555721
-
IL-33 and IL-33 receptors in host defense and diseases
-
Oboki K., Ohno T., Kajiwara N., Saito H., Nakae S. IL-33 and IL-33 receptors in host defense and diseases. Allergol. Int. 2010, 59:143-160.
-
(2010)
Allergol. Int.
, vol.59
, pp. 143-160
-
-
Oboki, K.1
Ohno, T.2
Kajiwara, N.3
Saito, H.4
Nakae, S.5
-
88
-
-
0029080727
-
A novel costimulatory factor for gamma interferon induction found in the livers of mice causes endotoxic shock
-
Okamura H., Nagata K., Komatsu T., Tanimoto T., Nukata Y., Tanabe F., Akita K., Torigoe K., Okura T., Fukuda S., et al. A novel costimulatory factor for gamma interferon induction found in the livers of mice causes endotoxic shock. Infect. Immun. 1995, 63:3966-3972.
-
(1995)
Infect. Immun.
, vol.63
, pp. 3966-3972
-
-
Okamura, H.1
Nagata, K.2
Komatsu, T.3
Tanimoto, T.4
Nukata, Y.5
Tanabe, F.6
Akita, K.7
Torigoe, K.8
Okura, T.9
Fukuda, S.10
-
89
-
-
33845438996
-
Human mast cell chymase cleaves pro-IL-18 and generates a novel and biologically active IL-18 fragment
-
Omoto Y., Tokime K., Yamanaka K., Habe K., Morioka T., Kurokawa I., Tsutsui H., Yamanishi K., Nakanishi K., Mizutani H. Human mast cell chymase cleaves pro-IL-18 and generates a novel and biologically active IL-18 fragment. J.Immunol. 2006, 177:8315-8319.
-
(2006)
J.Immunol.
, vol.177
, pp. 8315-8319
-
-
Omoto, Y.1
Tokime, K.2
Yamanaka, K.3
Habe, K.4
Morioka, T.5
Kurokawa, I.6
Tsutsui, H.7
Yamanishi, K.8
Nakanishi, K.9
Mizutani, H.10
-
90
-
-
77955050873
-
Granzyme B is a novel interleukin-18 converting enzyme
-
Omoto Y., Yamanaka K., Tokime K., Kitano S., Kakeda M., Akeda T., Kurokawa I., Gabazza E.C., Tsutsui H., Katayama N., et al. Granzyme B is a novel interleukin-18 converting enzyme. J.Dermatol. Sci. 2010, 59:129-135.
-
(2010)
J.Dermatol. Sci.
, vol.59
, pp. 129-135
-
-
Omoto, Y.1
Yamanaka, K.2
Tokime, K.3
Kitano, S.4
Kakeda, M.5
Akeda, T.6
Kurokawa, I.7
Gabazza, E.C.8
Tsutsui, H.9
Katayama, N.10
-
91
-
-
84893745158
-
Are mast cells instrumental for fibrotic diseases?
-
Overed-Sayer C., Rapley L., Mustelin T., Clarke D.L. Are mast cells instrumental for fibrotic diseases?. Front. Pharmacol. 2013, 4:174.
-
(2013)
Front. Pharmacol.
, vol.4
, pp. 174
-
-
Overed-Sayer, C.1
Rapley, L.2
Mustelin, T.3
Clarke, D.L.4
-
92
-
-
0035819245
-
IL-1H, aninterleukin 1-related protein that binds IL-18 receptor/IL-1Rrp
-
Pan G., Risser P., Mao W., Baldwin D.T., Zhong A.W., Filvaroff E., Yansura D., Lewis L., Eigenbrot C., Henzel W.J., Vandlen R. IL-1H, aninterleukin 1-related protein that binds IL-18 receptor/IL-1Rrp. Cytokine 2001, 13:1-7.
-
(2001)
Cytokine
, vol.13
, pp. 1-7
-
-
Pan, G.1
Risser, P.2
Mao, W.3
Baldwin, D.T.4
Zhong, A.W.5
Filvaroff, E.6
Yansura, D.7
Lewis, L.8
Eigenbrot, C.9
Henzel, W.J.10
Vandlen, R.11
-
93
-
-
84889653647
-
Emerging role of interleukin-33 in autoimmune diseases
-
Pei C., Barbour M., Fairlie-Clarke K.J., Allan D., Mu R., Jiang H.R. Emerging role of interleukin-33 in autoimmune diseases. Immunology 2014, 141:9-17.
-
(2014)
Immunology
, vol.141
, pp. 9-17
-
-
Pei, C.1
Barbour, M.2
Fairlie-Clarke, K.J.3
Allan, D.4
Mu, R.5
Jiang, H.R.6
-
94
-
-
84865642101
-
Interleukin-1 beta and transforming growth factor-beta 3 cooperate to activate matrix metalloproteinase expression and invasiveness in A549 lung adenocarcinoma cells
-
Petrella B.L., Armstrong D.A., Vincenti M.P. Interleukin-1 beta and transforming growth factor-beta 3 cooperate to activate matrix metalloproteinase expression and invasiveness in A549 lung adenocarcinoma cells. Cancer Lett. 2012, 325:220-226.
-
(2012)
Cancer Lett.
, vol.325
, pp. 220-226
-
-
Petrella, B.L.1
Armstrong, D.A.2
Vincenti, M.P.3
-
95
-
-
0023957427
-
Crystal structure of the cytokine interleukin-1 beta
-
Priestle J.P., Schär H.P., Grütter M.G. Crystal structure of the cytokine interleukin-1 beta. EMBO J. 1988, 7:339-343.
-
(1988)
EMBO J.
, vol.7
, pp. 339-343
-
-
Priestle, J.P.1
Schär, H.P.2
Grütter, M.G.3
-
96
-
-
80555133279
-
IL-1α and IL-1β recruit different myeloid cells and promote different stages of sterile inflammation
-
Rider P., Carmi Y., Guttman O., Braiman A., Cohen I., Voronov E., White M.R., Dinarello C.A., Apte R.N. IL-1α and IL-1β recruit different myeloid cells and promote different stages of sterile inflammation. J.Immunol. 2011, 187:4835-4843.
-
(2011)
J.Immunol.
, vol.187
, pp. 4835-4843
-
-
Rider, P.1
Carmi, Y.2
Guttman, O.3
Braiman, A.4
Cohen, I.5
Voronov, E.6
White, M.R.7
Dinarello, C.A.8
Apte, R.N.9
-
97
-
-
53249093714
-
Molecular mimicry between IL-33 and KSHV for attachment to chromatin through the H2A-H2B acidic pocket
-
Roussel L., Erard M., Cayrol C., Girard J.P. Molecular mimicry between IL-33 and KSHV for attachment to chromatin through the H2A-H2B acidic pocket. EMBO Rep. 2008, 9:1006-1012.
-
(2008)
EMBO Rep.
, vol.9
, pp. 1006-1012
-
-
Roussel, L.1
Erard, M.2
Cayrol, C.3
Girard, J.P.4
-
98
-
-
84891705895
-
Mast cell chymase degrades the alarmins heat shock protein 70, biglycan, HMGB1, and interleukin-33 (IL-33) and limits danger-induced inflammation
-
Roy A., Ganesh G., Sippola H., Bolin S., Sawesi O., Dagälv A., Schlenner S.M., Feyerabend T., Rodewald H.R., Kjellén L., et al. Mast cell chymase degrades the alarmins heat shock protein 70, biglycan, HMGB1, and interleukin-33 (IL-33) and limits danger-induced inflammation. J.Biol. Chem. 2014, 289:237-250.
-
(2014)
J.Biol. Chem.
, vol.289
, pp. 237-250
-
-
Roy, A.1
Ganesh, G.2
Sippola, H.3
Bolin, S.4
Sawesi, O.5
Dagälv, A.6
Schlenner, S.M.7
Feyerabend, T.8
Rodewald, H.R.9
Kjellén, L.10
-
99
-
-
0141727395
-
Pralnacasan, an inhibitor of interleukin-1beta converting enzyme, reduces joint damage in two murine models of osteoarthritis
-
Rudolphi K., Gerwin N., Verzijl N., van der Kraan P., van den Berg W. Pralnacasan, an inhibitor of interleukin-1beta converting enzyme, reduces joint damage in two murine models of osteoarthritis. Osteoarthritis Cartilage 2003, 11:738-746.
-
(2003)
Osteoarthritis Cartilage
, vol.11
, pp. 738-746
-
-
Rudolphi, K.1
Gerwin, N.2
Verzijl, N.3
van der Kraan, P.4
van den Berg, W.5
-
100
-
-
0035008905
-
Juxtacrine effects of IL-1 alpha precursor promote iNOS expression in vascular smooth muscle cells
-
Sasu S., Cooper A.L., Beasley D. Juxtacrine effects of IL-1 alpha precursor promote iNOS expression in vascular smooth muscle cells. Am. J. Physiol. Heart Circ. Physiol. 2001, 280:H1615-H1623.
-
(2001)
Am. J. Physiol. Heart Circ. Physiol.
, vol.280
, pp. H1615-H1623
-
-
Sasu, S.1
Cooper, A.L.2
Beasley, D.3
-
101
-
-
27744446058
-
IL-33, an interleukin-1-like cytokine that signals via the IL-1 receptor-related protein ST2 and induces T helper type 2-associated cytokines
-
Schmitz J., Owyang A., Oldham E., Song Y., Murphy E., McClanahan T.K., Zurawski G., Moshrefi M., Qin J., Li X., et al. IL-33, an interleukin-1-like cytokine that signals via the IL-1 receptor-related protein ST2 and induces T helper type 2-associated cytokines. Immunity 2005, 23:479-490.
-
(2005)
Immunity
, vol.23
, pp. 479-490
-
-
Schmitz, J.1
Owyang, A.2
Oldham, E.3
Song, Y.4
Murphy, E.5
McClanahan, T.K.6
Zurawski, G.7
Moshrefi, M.8
Qin, J.9
Li, X.10
-
102
-
-
45949111754
-
The IL-1 family member 7b translocates to the nucleus and down-regulates proinflammatory cytokines
-
Sharma S., Kulk N., Nold M.F., Gräf R., Kim S.H., Reinhardt D., Dinarello C.A., Bufler P. The IL-1 family member 7b translocates to the nucleus and down-regulates proinflammatory cytokines. J.Immunol. 2008, 180:5477-5482.
-
(2008)
J.Immunol.
, vol.180
, pp. 5477-5482
-
-
Sharma, S.1
Kulk, N.2
Nold, M.F.3
Gräf, R.4
Kim, S.H.5
Reinhardt, D.6
Dinarello, C.A.7
Bufler, P.8
-
103
-
-
84896500701
-
Cutting edge: Endoplasmic reticulum stress licenses macrophages to produce mature IL-1β in response to TLR4 stimulation through a caspase-8- and TRIF-dependent pathway
-
Shenderov K., Riteau N., Yip R., Mayer-Barber K.D., Oland S., Hieny S., Fitzgerald P., Oberst A., Dillon C.P., Green D.R., et al. Cutting edge: Endoplasmic reticulum stress licenses macrophages to produce mature IL-1β in response to TLR4 stimulation through a caspase-8- and TRIF-dependent pathway. J.Immunol. 2014, 192:2029-2033.
-
(2014)
J.Immunol.
, vol.192
, pp. 2029-2033
-
-
Shenderov, K.1
Riteau, N.2
Yip, R.3
Mayer-Barber, K.D.4
Oland, S.5
Hieny, S.6
Fitzgerald, P.7
Oberst, A.8
Dillon, C.P.9
Green, D.R.10
-
104
-
-
0033958252
-
Four new members expand the interleukin-1 superfamily
-
Smith D.E., Renshaw B.R., Ketchem R.R., Kubin M., Garka K.E., Sims J.E. Four new members expand the interleukin-1 superfamily. J.Biol. Chem. 2000, 275:1169-1175.
-
(2000)
J.Biol. Chem.
, vol.275
, pp. 1169-1175
-
-
Smith, D.E.1
Renshaw, B.R.2
Ketchem, R.R.3
Kubin, M.4
Garka, K.E.5
Sims, J.E.6
-
105
-
-
0035575705
-
Neutrophil proteinase 3-mediated induction of bioactive IL-18 secretion by human oral epithelial cells
-
Sugawara S., Uehara A., Nochi T., Yamaguchi T., Ueda H., Sugiyama A., Hanzawa K., Kumagai K., Okamura H., Takada H. Neutrophil proteinase 3-mediated induction of bioactive IL-18 secretion by human oral epithelial cells. J.Immunol. 2001, 167:6568-6575.
-
(2001)
J.Immunol.
, vol.167
, pp. 6568-6575
-
-
Sugawara, S.1
Uehara, A.2
Nochi, T.3
Yamaguchi, T.4
Ueda, H.5
Sugiyama, A.6
Hanzawa, K.7
Kumagai, K.8
Okamura, H.9
Takada, H.10
-
106
-
-
84892788781
-
Generalized pustular psoriasis triggered by amoxicillin in monozygotic twins with compound heterozygous IL36RN mutations: comment on the article by Navarini etal
-
Sugiura K., Shoda Y., Akiyama M. Generalized pustular psoriasis triggered by amoxicillin in monozygotic twins with compound heterozygous IL36RN mutations: comment on the article by Navarini etal. J.Invest. Dermatol. 2014, 134:578-579.
-
(2014)
J.Invest. Dermatol.
, vol.134
, pp. 578-579
-
-
Sugiura, K.1
Shoda, Y.2
Akiyama, M.3
-
107
-
-
67651053209
-
Interleukin-33 is biologically active independently of caspase-1 cleavage
-
Talabot-Ayer D., Lamacchia C., Gabay C., Palmer G. Interleukin-33 is biologically active independently of caspase-1 cleavage. J.Biol. Chem. 2009, 284:19420-19426.
-
(2009)
J.Biol. Chem.
, vol.284
, pp. 19420-19426
-
-
Talabot-Ayer, D.1
Lamacchia, C.2
Gabay, C.3
Palmer, G.4
-
108
-
-
0026507126
-
A novel heterodimeric cysteine protease is required for interleukin-1 beta processing in monocytes
-
Thornberry N.A., Bull H.G., Calaycay J.R., Chapman K.T., Howard A.D., Kostura M.J., Miller D.K., Molineaux S.M., Weidner J.R., Aunins J., et al. A novel heterodimeric cysteine protease is required for interleukin-1 beta processing in monocytes. Nature 1992, 356:768-774.
-
(1992)
Nature
, vol.356
, pp. 768-774
-
-
Thornberry, N.A.1
Bull, H.G.2
Calaycay, J.R.3
Chapman, K.T.4
Howard, A.D.5
Kostura, M.J.6
Miller, D.K.7
Molineaux, S.M.8
Weidner, J.R.9
Aunins, J.10
-
109
-
-
82755163088
-
Interleukin-36 (IL-36) ligands require processing for full agonist (IL-36α, IL-36β, and IL-36γ) or antagonist (IL-36Ra) activity
-
Towne J.E., Renshaw B.R., Douangpanya J., Lipsky B.P., Shen M., Gabel C.A., Sims J.E. Interleukin-36 (IL-36) ligands require processing for full agonist (IL-36α, IL-36β, and IL-36γ) or antagonist (IL-36Ra) activity. J.Biol. Chem. 2011, 286:42594-42602.
-
(2011)
J.Biol. Chem.
, vol.286
, pp. 42594-42602
-
-
Towne, J.E.1
Renshaw, B.R.2
Douangpanya, J.3
Lipsky, B.P.4
Shen, M.5
Gabel, C.A.6
Sims, J.E.7
-
110
-
-
0033198677
-
Caspase-1-independent, Fas/Fas ligand-mediated IL-18 secretion from macrophages causes acute liver injury in mice
-
Tsutsui H., Kayagaki N., Kuida K., Nakano H., Hayashi N., Takeda K., Matsui K., Kashiwamura S., Hada T., Akira S., et al. Caspase-1-independent, Fas/Fas ligand-mediated IL-18 secretion from macrophages causes acute liver injury in mice. Immunity 1999, 11:359-367.
-
(1999)
Immunity
, vol.11
, pp. 359-367
-
-
Tsutsui, H.1
Kayagaki, N.2
Kuida, K.3
Nakano, H.4
Hayashi, N.5
Takeda, K.6
Matsui, K.7
Kashiwamura, S.8
Hada, T.9
Akira, S.10
-
111
-
-
15844367093
-
Cloning of the cDNA for human IFN-gamma-inducing factor, expression in Escherichia coli, and studies on the biologic activities of the protein
-
Ushio S., Namba M., Okura T., Hattori K., Nukada Y., Akita K., Tanabe F., Konishi K., Micallef M., Fujii M., et al. Cloning of the cDNA for human IFN-gamma-inducing factor, expression in Escherichia coli, and studies on the biologic activities of the protein. J.Immunol. 1996, 156:4274-4279.
-
(1996)
J.Immunol.
, vol.156
, pp. 4274-4279
-
-
Ushio, S.1
Namba, M.2
Okura, T.3
Hattori, K.4
Nukada, Y.5
Akita, K.6
Tanabe, F.7
Konishi, K.8
Micallef, M.9
Fujii, M.10
-
112
-
-
82755198022
-
Proliferative versus apoptotic functions of caspase-8 Hetero or homo: the caspase-8 dimer controls cell fate
-
van Raam B.J., Salvesen G.S. Proliferative versus apoptotic functions of caspase-8 Hetero or homo: the caspase-8 dimer controls cell fate. Biochim. Biophys. Acta 2012, 1824:113-122.
-
(2012)
Biochim. Biophys. Acta
, vol.1824
, pp. 113-122
-
-
van Raam, B.J.1
Salvesen, G.S.2
-
113
-
-
84897945579
-
The role IL-1 in tumor-mediated angiogenesis
-
Voronov E., Carmi Y., Apte R.N. The role IL-1 in tumor-mediated angiogenesis. Front. Physiol. 2014, 5:114.
-
(2014)
Front. Physiol.
, vol.5
, pp. 114
-
-
Voronov, E.1
Carmi, Y.2
Apte, R.N.3
-
114
-
-
84883190168
-
Mast cell chymase modulates IL-33 levels and controls allergic sensitization in dust-mite induced airway inflammation
-
Waern I., Lundequist A., Pejler G., Wernersson S. Mast cell chymase modulates IL-33 levels and controls allergic sensitization in dust-mite induced airway inflammation. Mucosal Immunol. 2013, 6:911-920.
-
(2013)
Mucosal Immunol.
, vol.6
, pp. 911-920
-
-
Waern, I.1
Lundequist, A.2
Pejler, G.3
Wernersson, S.4
-
115
-
-
1442306085
-
The precursor form of IL-1alpha is an intracrine proinflammatory activator of transcription
-
Werman A., Werman-Venkert R., White R., Lee J.K., Werman B., Krelin Y., Voronov E., Dinarello C.A., Apte R.N. The precursor form of IL-1alpha is an intracrine proinflammatory activator of transcription. Proc. Natl. Acad. Sci. USA 2004, 101:2434-2439.
-
(2004)
Proc. Natl. Acad. Sci. USA
, vol.101
, pp. 2434-2439
-
-
Werman, A.1
Werman-Venkert, R.2
White, R.3
Lee, J.K.4
Werman, B.5
Krelin, Y.6
Voronov, E.7
Dinarello, C.A.8
Apte, R.N.9
-
116
-
-
0027451982
-
Identification of a nuclear localization sequence within the structure of the human interleukin-1 alpha precursor
-
Wessendorf J.H., Garfinkel S., Zhan X., Brown S., Maciag T. Identification of a nuclear localization sequence within the structure of the human interleukin-1 alpha precursor. J.Biol. Chem. 1993, 268:22100-22104.
-
(1993)
J.Biol. Chem.
, vol.268
, pp. 22100-22104
-
-
Wessendorf, J.H.1
Garfinkel, S.2
Zhan, X.3
Brown, S.4
Maciag, T.5
-
117
-
-
27144524157
-
Amelioration of experimental arthritis by a calpain-inhibitory compound: regulation of cytokine production by E-64-d invivo and invitro
-
Yoshifuji H., Umehara H., Maruyama H., Itoh M., Tanaka M., Kawabata D., Fujii T., Mimori T. Amelioration of experimental arthritis by a calpain-inhibitory compound: regulation of cytokine production by E-64-d invivo and invitro. Int. Immunol. 2005, 17:1327-1336.
-
(2005)
Int. Immunol.
, vol.17
, pp. 1327-1336
-
-
Yoshifuji, H.1
Umehara, H.2
Maruyama, H.3
Itoh, M.4
Tanaka, M.5
Kawabata, D.6
Fujii, T.7
Mimori, T.8
-
118
-
-
0029157723
-
Resistance to fever induction and impaired acute-phase response in interleukin-1 beta-deficient mice
-
Zheng H., Fletcher D., Kozak W., Jiang M., Hofmann K.J., Conn C.A., Soszynski D., Grabiec C., Trumbauer M.E., Shaw A., et al. Resistance to fever induction and impaired acute-phase response in interleukin-1 beta-deficient mice. Immunity 1995, 3:9-19.
-
(1995)
Immunity
, vol.3
, pp. 9-19
-
-
Zheng, H.1
Fletcher, D.2
Kozak, W.3
Jiang, M.4
Hofmann, K.J.5
Conn, C.A.6
Soszynski, D.7
Grabiec, C.8
Trumbauer, M.E.9
Shaw, A.10
-
119
-
-
84874248044
-
Intracellular interleukin-1 receptor 2 binding prevents cleavage and activity of interleukin-1α, controlling necrosis-induced sterile inflammation
-
Zheng Y., Humphry M., Maguire J.J., Bennett M.R., Clarke M.C. Intracellular interleukin-1 receptor 2 binding prevents cleavage and activity of interleukin-1α, controlling necrosis-induced sterile inflammation. Immunity 2013, 38:285-295.
-
(2013)
Immunity
, vol.38
, pp. 285-295
-
-
Zheng, Y.1
Humphry, M.2
Maguire, J.J.3
Bennett, M.R.4
Clarke, M.C.5
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