-
1
-
-
73649088291
-
Local interleukin-1-driven joint pathology is dependent on toll-like receptor 4 activation
-
Abdollahi-Roodsaz, S., Joosten, L. A., Koenders, M. I., Van Den Brand, B. T., Van De Loo, F. A., and Van Den Berg, W. B. (2009). Local interleukin-1-driven joint pathology is dependent on toll-like receptor 4 activation. Am. J. Pathol. 175, 2004-2013.
-
(2009)
Am. J. Pathol.
, vol.175
, pp. 2004-2013
-
-
Abdollahi-Roodsaz, S.1
Joosten, L.A.2
Koenders, M.I.3
Van Den Brand, B.T.4
Van De Loo, F.A.5
Van Den Berg, W.B.6
-
2
-
-
34548125305
-
Interleukins 1beta and 6 but not transforming growthfactor-beta are essential for the differentiation of interleukin 17-producing human T helper cells
-
Acosta-Rodriguez, E. V., Napolitani, G., Lanzavecchia, A., and Sallusto, F. (2007). Interleukins 1beta and 6 but not transforming growthfactor-beta are essential for the differentiation of interleukin 17-producing human T helper cells. Nat. Immunol. 8, 942-949.
-
(2007)
Nat. Immunol.
, vol.8
, pp. 942-949
-
-
Acosta-Rodriguez, E.V.1
Napolitani, G.2
Lanzavecchia, A.3
Sallusto, F.4
-
3
-
-
33747514521
-
Up-regulation of MyD88s and SIGIRR, molecules inhibiting toll-like receptor signaling, in monocytes from septic patients
-
Adib-Conquy, M., Adrie, C., Fitting, C., Gattolliat, O., Beyaert, R., and Cavaillon, J. M. (2006). Up-regulation of MyD88s and SIGIRR, molecules inhibiting toll-like receptor signaling, in monocytes from septic patients. Crit. Care Med. 34, 2377-2385.
-
(2006)
Crit. Care Med.
, vol.34
, pp. 2377-2385
-
-
Adib-Conquy, M.1
Adrie, C.2
Fitting, C.3
Gattolliat, O.4
Beyaert, R.5
Cavaillon, J.M.6
-
4
-
-
66649121678
-
An autoinflammatory disease with deficiency of the interleukin-1-receptor antagonist
-
Aksentijevich, I., Masters, S. L., Ferguson, P. J., Dancey, P., Frenkel, J., Van Royen-Kerkhoff, A., et al. (2009). An autoinflammatory disease with deficiency of the interleukin-1-receptor antagonist. N. Engl. J. Med. 360, 2426-2437.
-
(2009)
N. Engl. J. Med.
, vol.360
, pp. 2426-2437
-
-
Aksentijevich, I.1
Masters, S.L.2
Ferguson, P.J.3
Dancey, P.4
Frenkel, J.5
Van Royen-Kerkhoff, A.6
-
5
-
-
26844554608
-
Regulationof expression of the novel IL-1 receptor family members in the mouse brain
-
Andre, R., Lerouet, D., Kimber, I., Pin-teaux, E., and Rothwell, N. J. (2005). Regulationof expression of the novel IL-1 receptor family members in the mouse brain. J. Neurochem. 95, 324-330.
-
(2005)
J. Neurochem.
, vol.95
, pp. 324-330
-
-
Andre, R.1
Lerouet, D.2
Kimber, I.3
Pin-teaux, E.4
Rothwell, N.J.5
-
6
-
-
0344826531
-
Colonic polyposis caused by mTOR-mediated chromosomal instability in Apc+/Delta716 Cdx2+(-compound mutant mice
-
Aoki, K., Tamai, Y., Horiike, S., Oshima, M., and Taketo, M. M. (2003). Colonic polyposis caused by mTOR-mediated chromosomal instability in Apc+/Delta716 Cdx2+(-compound mutant mice. Nat. Genet. 35, 323-330.
-
(2003)
Nat. Genet.
, vol.35
, pp. 323-330
-
-
Aoki, K.1
Tamai, Y.2
Horiike, S.3
Oshima, M.4
Taketo, M.M.5
-
7
-
-
20444373390
-
MyD88-deficient mice develop severe intestinal inflammation in dextran sodium sulfate colitis
-
Araki, A., Kanai, T., Ishikura, T., Makita, S., Uraushihara, K., Iiyama, R., et al. (2005). MyD88-deficient mice develop severe intestinal inflammation in dextran sodium sulfate colitis. J. Gastroenterol. 40, 16-23.
-
(2005)
J. Gastroenterol.
, vol.40
, pp. 16-23
-
-
Araki, A.1
Kanai, T.2
Ishikura, T.3
Makita, S.4
Uraushihara, K.5
Iiyama, R.6
-
8
-
-
80355126549
-
Toll-like receptor signaling pathway in chronic lympho-cytic leukemia: distinct gene expression profiles of potential pathogenic significance in specific subsets of patients
-
Arvaniti, E., Ntoufa, S., Papakon-stantinou, N., Touloumenidou, T., Laoutaris, N., Anagnostopoulos, A., et al. (2011). Toll-like receptor signaling pathway in chronic lympho-cytic leukemia: distinct gene expression profiles of potential pathogenic significance in specific subsets of patients. Haematologica 96, 1644-1652.
-
(2011)
Haematologica
, vol.96
, pp. 1644-1652
-
-
Arvaniti, E.1
Ntoufa, S.2
Papakon-stantinou, N.3
Touloumenidou, T.4
Laoutaris, N.5
Anagnostopoulos, A.6
-
9
-
-
33646507867
-
Microarray analyses of peripheral blood cells identifies unique gene expression signature in psoriatic arthritis
-
Batliwalla, F. M., Li, W., Ritchlin, C. T., Xiao, X., Brenner, M., Laragione, T., et al. (2005). Microarray analyses of peripheral blood cells identifies unique gene expression signature in psoriatic arthritis. Mol. Med. 11, 21-29.
-
(2005)
Mol. Med.
, vol.11
, pp. 21-29
-
-
Batliwalla, F.M.1
Li, W.2
Ritchlin, C.T.3
Xiao, X.4
Brenner, M.5
Laragione, T.6
-
10
-
-
65249131826
-
Induction and regulatory function of miR-9 in human mono-cytes and neutrophils exposed to proinflammatory signals
-
Bazzoni, F., Rossato, M., Fabbri, M., Gaudiosi, D., Mirolo, M., Mori, L., et al. (2009). Induction and regulatory function of miR-9 in human mono-cytes and neutrophils exposed to proinflammatory signals. Proc. Natl. Acad. Sci. U.S.A. 106, 5282-5287.
-
(2009)
Proc. Natl. Acad. Sci. U.S.A.
, vol.106
, pp. 5282-5287
-
-
Bazzoni, F.1
Rossato, M.2
Fabbri, M.3
Gaudiosi, D.4
Mirolo, M.5
Mori, L.6
-
11
-
-
80052014052
-
Inflammation meets cancer, with NF-kappaBasthe matchmaker
-
Ben-Neriah, Y., and Karin, M. (2011). Inflammation meets cancer, with NF-kappaBasthe matchmaker.Nat. Immunol. 12, 715-723.
-
(2011)
Nat. Immunol.
, vol.12
, pp. 715-723
-
-
Ben-Neriah, Y.1
Karin, M.2
-
12
-
-
79960691639
-
Lack of TIR8/SIGIRR triggers progression of chronic lymphocytic leukemia in mouse models
-
Bertilaccio, M. T., Simonetti, G., Dagk-lis, A., Rocchi, M., Rodriguez, T. V., Apollonio, B., et al. (2011). Lack of TIR8/SIGIRR triggers progression of chronic lymphocytic leukemia in mouse models. Blood 118, 660-669.
-
(2011)
Blood
, vol.118
, pp. 660-669
-
-
Bertilaccio, M.T.1
Simonetti, G.2
Dagk-lis, A.3
Rocchi, M.4
Rodriguez, T.V.5
Apollonio, B.6
-
13
-
-
0037076279
-
Human chronic lymphocytic leukemia modeled in mouse by targeted TCL1 expression
-
Bichi, R., Shinton, S. A., Martin, E. S., Koval, A., Calin, G. A., Cesari, R., et al. (2002). Human chronic lymphocytic leukemia modeled in mouse by targeted TCL1 expression. Proc. Natl. Acad. Sci. U.S.A. 99, 6955-6960.
-
(2002)
Proc. Natl. Acad. Sci. U.S.A.
, vol.99
, pp. 6955-6960
-
-
Bichi, R.1
Shinton, S.A.2
Martin, E.S.3
Koval, A.4
Calin, G.A.5
Cesari, R.6
-
14
-
-
77956976681
-
Macrophage plasticity and interaction with lymphocyte subsets: cancer as a paradigm
-
Biswas, S. K., and Mantovani,A. (2010). Macrophage plasticity and interaction with lymphocyte subsets: cancer as a paradigm. Nat. Immunol. 11, 889-896.
-
(2010)
Nat. Immunol.
, vol.11
, pp. 889-896
-
-
Biswas, S.K.1
Mantovani, A.2
-
15
-
-
83055163376
-
IL-37: a new anti-inflammatory cytokine of the IL-1 family
-
Boraschi, D., Lucchesi, D., Hainzl, S., Leitner, M., Maier, E., Mangelberger, D., et al. (2011). IL-37: a new anti-inflammatory cytokine of the IL-1 family. Eur. Cytokine Netw. 22, 127-147.
-
(2011)
Eur. Cytokine Netw.
, vol.22
, pp. 127-147
-
-
Boraschi, D.1
Lucchesi, D.2
Hainzl, S.3
Leitner, M.4
Maier, E.5
Mangelberger, D.6
-
16
-
-
44849100683
-
Lack of Toll IL-1R8 exacerbates Th17 cell responses in fungal infection
-
Bozza, S., Zelante, T., Moretti, S., Boni-fazi, P., Deluca, A., D'angelo, C., et al. (2008). Lack of Toll IL-1R8 exacerbates Th17 cell responses in fungal infection. J. Immunol. 180, 4022-4031.
-
(2008)
J. Immunol.
, vol.180
, pp. 4022-4031
-
-
Bozza, S.1
Zelante, T.2
Moretti, S.3
Boni-fazi, P.4
Deluca, A.5
D'angelo, C.6
-
17
-
-
64849087206
-
The essential role of single Ig IL-1 receptor-related molecule/Toll IL-1R8 in regulationof Th2 immune response
-
Bulek, K., Swaidani, S., Qin, J., Lu, Y., Gulen, M. F., Herjan, T., et al. (2009). The essential role of single Ig IL-1 receptor-related molecule/Toll IL-1R8 in regulationof Th2 immune response. J. Immunol. 182, 2601-2609.
-
(2009)
J. Immunol.
, vol.182
, pp. 2601-2609
-
-
Bulek, K.1
Swaidani, S.2
Qin, J.3
Lu, Y.4
Gulen, M.F.5
Herjan, T.6
-
18
-
-
58149149839
-
TLR3 is an endogenous sensor of tissue necrosis during acute inflammatory events
-
Cavassani, K. A., Ishii, M., Wen, H., Schaller, M. A., Lincoln, P. M., Lukacs, N. W., et al. (2008). TLR3 is an endogenous sensor of tissue necrosis during acute inflammatory events. J. Exp. Med. 205, 2609-2621.
-
(2008)
J. Exp. Med.
, vol.205
, pp. 2609-2621
-
-
Cavassani, K.A.1
Ishii, M.2
Wen, H.3
Schaller, M.A.4
Lincoln, P.M.5
Lukacs, N.W.6
-
19
-
-
0035423397
-
Human IL-18 receptor and ST2L are stable and selective markers for the respective type 1 and type 2 circulating lymphocytes
-
Chan, W. L., Pejnovic, N., Lee, C. A., and Al-Ali, N. A. (2001). Human IL-18 receptor and ST2L are stable and selective markers for the respective type 1 and type 2 circulating lymphocytes. J. Immunol. 167, 1238-1244.
-
(2001)
J. Immunol.
, vol.167
, pp. 1238-1244
-
-
Chan, W.L.1
Pejnovic, N.2
Lee, C.A.3
Al-Ali, N.A.4
-
20
-
-
78751627946
-
Enhanced expression of single immunoglobulin IL-1 receptor-related molecule ameliorates LPS-induced acute lung injury in mice
-
Chen, X., Zhao, Y., Wu, X., and Qian, G. (2011). Enhanced expression of single immunoglobulin IL-1 receptor-related molecule ameliorates LPS-induced acute lung injury in mice. Shock 35, 198-204.
-
(2011)
Shock
, vol.35
, pp. 198-204
-
-
Chen, X.1
Zhao, Y.2
Wu, X.3
Qian, G.4
-
21
-
-
77951196379
-
Triggering of TLR7 and TLR8 expressedbyhuman lung cancer cells induces cell survival and chemoresistance
-
Cherfils-Vicini, J., Platonova, S., Gillard, M., Laurans, L., Validire, P., Calian-dro, R., et al. (2010). Triggering of TLR7 and TLR8 expressedbyhuman lung cancer cells induces cell survival and chemoresistance. J. Clin. Invest. 120, 1285-1297.
-
(2010)
J. Clin. Invest.
, vol.120
, pp. 1285-1297
-
-
Cherfils-Vicini, J.1
Platonova, S.2
Gillard, M.3
Laurans, L.4
Validire, P.5
Calian-dro, R.6
-
22
-
-
77951246550
-
Endogenous ligands for TLR2 and TLR4 are not involved in renal injury following ureteric obstruction
-
Chowdhury, P., Sacks, S. H., and Sheerin, N. S. (2010). Endogenous ligands for TLR2 and TLR4 are not involved in renal injury following ureteric obstruction. Nephron Exp. Nephrol. 115, e122-e130.
-
(2010)
Nephron Exp. Nephrol.
, vol.115
-
-
Chowdhury, P.1
Sacks, S.H.2
Sheerin, N.S.3
-
23
-
-
67650151005
-
Cancer-related inflammation, the seventh hallmark of cancer: links to genetic instability
-
Colotta, F., Allavena, P., Sica, A., Gar-landa, C., and Mantovani,A. (2009). Cancer-related inflammation, the seventh hallmark of cancer: links to genetic instability. Carcinogenesis 30, 1073-1081.
-
(2009)
Carcinogenesis
, vol.30
, pp. 1073-1081
-
-
Colotta, F.1
Allavena, P.2
Sica, A.3
Gar-landa, C.4
Mantovani, A.5
-
24
-
-
79952388696
-
Interleukin-1alpha and HMGB1 mediate hippocampal dysfunction in SIGIRR-deficient mice
-
Costello, D. A., Watson, M. B., Cow-ley, T. R., Murphy, N., Murphy Royal, C., Garlanda, C., et al. (2011). Interleukin-1alpha and HMGB1 mediate hippocampal dysfunction in SIGIRR-deficient mice. J. Neurosci. 31, 3871-3879.
-
(2011)
J. Neurosci.
, vol.31
, pp. 3871-3879
-
-
Costello, D.A.1
Watson, M.B.2
Cow-ley, T.R.3
Murphy, N.4
Murphy Royal, C.5
Garlanda, C.6
-
25
-
-
43549123287
-
IL-1F5 mediates anti-inflammatory activity in the brain through induction of IL-4 following interaction with SIGIRR/TIR8
-
Costelloe, C., Watson, M., Murphy, A., Mcquillan, K., Loscher, C., Armstrong, M. E., et al. (2008). IL-1F5 mediates anti-inflammatory activity in the brain through induction of IL-4 following interaction with SIGIRR/TIR8. J. Neurochem. 105, 1960-1969.
-
(2008)
J. Neurochem.
, vol.105
, pp. 1960-1969
-
-
Costelloe, C.1
Watson, M.2
Murphy, A.3
Mcquillan, K.4
Loscher, C.5
Armstrong, M.E.6
-
26
-
-
78649403533
-
Differential regulation of toll-like receptor signalling in spleen and Peyer's patch dendritic cells
-
Davies, J. M., Macsharry, J., and Shana-han, F. (2010). Differential regulation of toll-like receptor signalling in spleen and Peyer's patch dendritic cells. Immunology 131, 438-448.
-
(2010)
Immunology
, vol.131
, pp. 438-448
-
-
Davies, J.M.1
Macsharry, J.2
Shana-han, F.3
-
27
-
-
77958118283
-
IL-1 family nomenclature
-
Dinarello, C., Arend, W., Sims, J., Smith, D., Blumberg, H., O'Neill, L., et al. (2010). IL-1 family nomenclature. Nat. Immunol. 11, 973.
-
(2010)
Nat. Immunol.
, vol.11
, pp. 973
-
-
Dinarello, C.1
Arend, W.2
Sims, J.3
Smith, D.4
Blumberg, H.5
O'Neill, L.6
-
28
-
-
0034618862
-
The role of the interleukin-1-receptor antagonist in blocking inflammation mediated by interleukin-1
-
Dinarello, C. A. (2000). The role of the interleukin-1-receptor antagonist in blocking inflammation mediated by interleukin-1. N. Engl. J. Med. 343, 732-734.
-
(2000)
N. Engl. J. Med.
, vol.343
, pp. 732-734
-
-
Dinarello, C.A.1
-
29
-
-
62649139025
-
Immunological and inflammatory functions of the interleukin-1 family
-
Dinarello, C. A. (2009). Immunological and inflammatory functions of the interleukin-1 family. Annu. Rev. Immunol. 27, 519-550.
-
(2009)
Annu. Rev. Immunol.
, vol.27
, pp. 519-550
-
-
Dinarello, C.A.1
-
30
-
-
77649179676
-
The role of toll-like receptors in chronic inflammation
-
Drexler, S. K., and Foxwell, B. M. (2010). The role of toll-like receptors in chronic inflammation. Int. J. Biochem. Cell Biol. 42, 506-518.
-
(2010)
Int. J. Biochem. Cell Biol.
, vol.42
, pp. 506-518
-
-
Drexler, S.K.1
Foxwell, B.M.2
-
31
-
-
77955350086
-
SIGIRR/TIR-8 is an inhibitor of toll-like receptor signaling in primary human cells and regulates inflammation in models of rheumatoid arthritis
-
Drexler, S. K., Kong, P., Inglis, J., Williams, R. O., Garlanda, C., Man-tovani,A.,et al. (2010). SIGIRR/TIR-8 is an inhibitor of toll-like receptor signaling in primary human cells and regulates inflammation in models of rheumatoid arthritis. Arthritis Rheum. 62, 2249-2261.
-
(2010)
Arthritis Rheum
, vol.62
, pp. 2249-2261
-
-
Drexler, S.K.1
Kong, P.2
Inglis, J.3
Williams, R.O.4
Garlanda, C.5
Man-tovani, A.6
-
32
-
-
68949181883
-
TIR8/SIGIRR: anIL-1R/TLR family member with regulatory functions in inflammation and T cell polarization
-
Garlanda, C., Anders, H. J., and Manto-vani,A. (2009). TIR8/SIGIRR:anIL-1R/TLR family member with regulatory functions in inflammation and T cell polarization. Trends Immunol. 30, 439-446.
-
(2009)
Trends Immunol
, vol.30
, pp. 439-446
-
-
Garlanda, C.1
Anders, H.J.2
Manto-vani, A.3
-
33
-
-
38449105679
-
Damping excessive inflammation and tissue damage in Mycobacterium tuberculosis infection by toll IL-1 receptor 8/single Ig IL-1-related receptor, a negative regulator of IL-1/TLR signaling
-
Garlanda, C., Di Liberto, D., Vecchi, A., La Manna, M. P., Buracchi, C., Cac-camo, N., et al. (2007a). Damping excessive inflammation and tissue damage in Mycobacterium tuberculosis infection by toll IL-1 receptor 8/single Ig IL-1-related receptor, a negative regulator of IL-1/TLR signaling. J. Immunol. 179, 3119-3125.
-
(2007)
J. Immunol.
, vol.179
, pp. 3119-3125
-
-
Garlanda, C.1
Di Liberto, D.2
Vecchi, A.3
La Manna, M.P.4
Buracchi, C.5
Cac-camo, N.6
-
34
-
-
34447118220
-
Increased susceptibility to colitis-associated cancer of mice lacking TIR8, an inhibitory member of the interleukin-1 receptor family
-
Garlanda, C., Riva, F., Veliz, T., Polen-tarutti, N., Pasqualini, F., and Radaelli, E. (2007b). Increased susceptibility to colitis-associated cancer of mice lacking TIR8, an inhibitory member of the interleukin-1 receptor family. Cancer Res. 67, 6017-6021.
-
(2007)
Cancer Res
, vol.67
, pp. 6017-6021
-
-
Garlanda, C.1
Riva, F.2
Veliz, T.3
Polen-tarutti, N.4
Pasqualini, F.5
Radaelli, E.6
-
35
-
-
12144287484
-
Intestinal inflammation in mice deficient in Tir8, an inhibitory member of the IL-1 receptor family
-
Garlanda, C., Riva, F., Polentarutti, N., Buracchi,C.,Sironi, M.,and DeBor-toli, M. (2004). Intestinal inflammation in mice deficient in Tir8, an inhibitory member of the IL-1 receptor family. Proc. Natl. Acad. Sci. U.S.A. 101, 3522-3526.
-
(2004)
Proc. Natl. Acad. Sci. U.S.A.
, vol.101
, pp. 3522-3526
-
-
Garlanda, C.1
Riva, F.2
Polentarutti, N.3
Buracchi, C.4
Sironi, M.5
DeBor-toli, M.6
-
36
-
-
79952100792
-
What the Myddosome structure tells us about the initiation of innate immunity
-
Gay, N. J., Gangloff, M., and O'Neill, L. A. (2011). What the Myddosome structure tells us about the initiation of innate immunity. Trends Immunol. 32, 104-109.
-
(2011)
Trends Immunol
, vol.32
, pp. 104-109
-
-
Gay, N.J.1
Gangloff, M.2
O'Neill, L.A.3
-
37
-
-
33645971977
-
The origin of B-cell chronic lymphocytic leukemia
-
Ghia, P., and Caligaris-Cappio, F. (2006). The origin of B-cell chronic lymphocytic leukemia. Semin. Oncol. 33, 150-156.
-
(2006)
Semin. Oncol.
, vol.33
, pp. 150-156
-
-
Ghia, P.1
Caligaris-Cappio, F.2
-
38
-
-
76749092614
-
Inhibition of tolllike receptors TLR4 and 7 signaling pathways by SIGIRR: a computational approach
-
Gong, J., Wei, T., Stark, R. W., Jamitzky, F., Heckl, W. M., Anders, H. J., et al. (2010). Inhibition of tolllike receptors TLR4 and 7 signaling pathways by SIGIRR: a computational approach. J. Struct. Biol. 169, 323-330.
-
(2010)
J. Struct. Biol.
, vol.169
, pp. 323-330
-
-
Gong, J.1
Wei, T.2
Stark, R.W.3
Jamitzky, F.4
Heckl, W.M.5
Anders, H.J.6
-
39
-
-
55349137780
-
Regulation of toll-like receptors in intestinal epithelial cells by stress and Toxoplasma gondii infection
-
Gopal, R., Birdsell, D., and Monroy, F. P. (2008). Regulation of toll-like receptors in intestinal epithelial cells by stress and Toxoplasma gondii infection. Parasite Immunol. 30, 563-576.
-
(2008)
Parasite Immunol
, vol.30
, pp. 563-576
-
-
Gopal, R.1
Birdsell, D.2
Monroy, F.P.3
-
40
-
-
80052668568
-
Discovery of the DIGIRR gene from teleost fish: a novel toll-IL-1 receptor family member serving as a negative regulator of IL-1 signaling
-
Gu, Y. F., Fang, Y., Jin, Y., Dong, W. R., Xiang, L. X., and Shao, J. Z. (2011). Discovery of the DIGIRR gene from teleost fish: a novel toll-IL-1 receptor family member serving as a negative regulator of IL-1 signaling. J. Immunol. 187, 2514-2530.
-
(2011)
J. Immunol.
, vol.187
, pp. 2514-2530
-
-
Gu, Y.F.1
Fang, Y.2
Jin, Y.3
Dong, W.R.4
Xiang, L.X.5
Shao, J.Z.6
-
41
-
-
74649086985
-
The receptor SIGIRR suppresses Th17 cell proliferation via inhibition of the interleukin-1 receptor pathway and mTOR kinase activation
-
Gulen, M. F., Kang, Z., Bulek, K., Youzhong, W., Kim, T. W., Chen, Y., et al. (2010). The receptor SIGIRR suppresses Th17 cell proliferation via inhibition of the interleukin-1 receptor pathway and mTOR kinase activation. Immunity 32, 54-66.
-
(2010)
Immunity
, vol.32
, pp. 54-66
-
-
Gulen, M.F.1
Kang, Z.2
Bulek, K.3
Youzhong, W.4
Kim, T.W.5
Chen, Y.6
-
42
-
-
84856286185
-
Common polymorphisms in the PKP3-SIGIRR-TMEM16J gene region are associated with susceptibility to tuberculosis
-
Horne, D. J., Randhawa, A. K., Chau, T. T., Bang, N. D., Yen, N. T., Farrar, J. J., et al. (2012). Common polymorphisms in the PKP3-SIGIRR-TMEM16J gene region are associated with susceptibility to tuberculosis. J. Infect. Dis. 205, 586-594.
-
(2012)
J. Infect. Dis.
, vol.205
, pp. 586-594
-
-
Horne, D.J.1
Randhawa, A.K.2
Chau, T.T.3
Bang, N.D.4
Yen, N.T.5
Farrar, J.J.6
-
43
-
-
33745303252
-
SIGIRR promotes resistance against Pseudomonas aeruginosa ker-atitis by down-regulating type-1 immunity and IL-1R1 and TLR4 signaling
-
Huang, X., Hazlett, L. D., Du, W., and Barrett, R. P. (2006). SIGIRR promotes resistance against Pseudomonas aeruginosa ker-atitis by down-regulating type-1 immunity and IL-1R1 and TLR4 signaling. J. Immunol. 177, 548-556.
-
(2006)
J. Immunol.
, vol.177
, pp. 548-556
-
-
Huang, X.1
Hazlett, L.D.2
Du, W.3
Barrett, R.P.4
-
44
-
-
0042236366
-
MyD88S, a splice variant of MyD88, differentially modulates NF-kappaB-and AP-1-dependent gene expression
-
Janssens, S., Burns, K., Vercammen, E., Tschopp, J., and Beyaert, R. (2003). MyD88S, a splice variant of MyD88, differentially modulates NF-kappaB-and AP-1-dependent gene expression. FEBS Lett. 548, 103-107.
-
(2003)
FEBS Lett
, vol.548
, pp. 103-107
-
-
Janssens, S.1
Burns, K.2
Vercammen, E.3
Tschopp, J.4
Beyaert, R.5
-
45
-
-
84862857096
-
Vasoactive intestinal peptide downregulates proin-flammatory TLRs while upregulat-ing anti-inflammatory TLRs in the infected cornea
-
Jiang, X., Mcclellan, S. A., Barrett, R. P., Zhang, Y., and Hazlett, L. D. (2012). Vasoactive intestinal peptide downregulates proin-flammatory TLRs while upregulat-ing anti-inflammatory TLRs in the infected cornea. J. Immunol. 189, 269-278.
-
(2012)
J. Immunol.
, vol.189
, pp. 269-278
-
-
Jiang, X.1
Mcclellan, S.A.2
Barrett, R.P.3
Zhang, Y.4
Hazlett, L.D.5
-
46
-
-
78649287637
-
Down-regulation of single immunoglobulin interleukin-1R-related molecule (SIGIRR)/TIR8 expression in intestinal epithelial cellsduring inflammation
-
Kadota, C., Ishihara, S., Aziz, M. M., Rumi, M. A., Oshima, N., Mishima, Y., et al. (2010). Down-regulation of single immunoglobulin interleukin-1R-related molecule (SIGIRR)/TIR8 expression in intestinal epithelial cellsduring inflammation.Clin. Exp. Immunol. 162, 348-361.
-
(2010)
Clin. Exp. Immunol.
, vol.162
, pp. 348-361
-
-
Kadota, C.1
Ishihara, S.2
Aziz, M.M.3
Rumi, M.A.4
Oshima, N.5
Mishima, Y.6
-
47
-
-
79959447465
-
Structural biology of the toll-like receptor family
-
Kang, J. Y., and Lee, J. O. (2011). Structural biology of the toll-like receptor family. Annu. Rev. Biochem. 80, 917-941.
-
(2011)
Annu. Rev. Biochem.
, vol.80
, pp. 917-941
-
-
Kang, J.Y.1
Lee, J.O.2
-
48
-
-
33745298519
-
Nuclear factor-kappaB in cancer development and progression
-
Karin, M. (2006). Nuclear factor-kappaB in cancer development and progression. Nature 441, 431-436.
-
(2006)
Nature
, vol.441
, pp. 431-436
-
-
Karin, M.1
-
49
-
-
32944474237
-
Innate immunity gone awry: linking microbial infections to chronic inflammation and cancer
-
Karin, M., Lawrence, T., and Nizet, V. (2006). Innate immunity gone awry: linking microbial infections to chronic inflammation and cancer. Cell 124, 823-835.
-
(2006)
Cell
, vol.124
, pp. 823-835
-
-
Karin, M.1
Lawrence, T.2
Nizet, V.3
-
50
-
-
77951922771
-
The single IgG IL-1-related receptor controls TLR responses in differentiated human intestinal epithelial cells
-
Khan, M. A., Steiner, T. S., Sham, H. P., Bergstrom, K. S., Huang, J. T., Assi, K., et al. (2010). The single IgG IL-1-related receptor controls TLR responses in differentiated human intestinal epithelial cells. J. Immunol. 184, 2305-2313.
-
(2010)
J. Immunol.
, vol.184
, pp. 2305-2313
-
-
Khan, M.A.1
Steiner, T.S.2
Sham, H.P.3
Bergstrom, K.S.4
Huang, J.T.5
Assi, K.6
-
51
-
-
0037178785
-
IRAK-M is a negative regulator of toll-like receptor signaling
-
Kobayashi, K., Hernandez, L. D., Galan, J. E., Janeway, C. A. Jr., Medzhi-tov, R., and Flavell, R. A. (2002). IRAK-M is a negative regulator of toll-like receptor signaling. Cell 110, 191-202.
-
(2002)
Cell
, vol.110
, pp. 191-202
-
-
Kobayashi, K.1
Hernandez, L.D.2
Galan, J.E.3
Janeway Jr., C.A.4
Medzhi-tov, R.5
Flavell, R.A.6
-
52
-
-
0037061453
-
Chromatin-IgG complexes activate B cells by dual engagement of IgM and toll-like receptors
-
Leadbetter, E. A., Rifkin, I. R., Hohlbaum, A. M., Beaudette, B. C., Shlomchik, M. J., and Marshak-Rothstein, A. (2002). Chromatin-IgG complexes activate B cells by dual engagement of IgM and toll-like receptors. Nature 416, 603-607.
-
(2002)
Nature
, vol.416
, pp. 603-607
-
-
Leadbetter, E.A.1
Rifkin, I.R.2
Hohlbaum, A.M.3
Beaudette, B.C.4
Shlomchik, M.J.5
Marshak-Rothstein, A.6
-
53
-
-
70349320167
-
Resident dendritic cells prevent postischemic acute renal failure by help of single Ig IL-1 receptor-related protein
-
Lech, M., Avila-Ferrufino, A., Allam, R., Segerer, S., Khandoga, A., Krom-bach, F., et al. (2009). Resident dendritic cells prevent postischemic acute renal failure by help of single Ig IL-1 receptor-related protein. J. Immunol. 183, 4109-4118.
-
(2009)
J. Immunol.
, vol.183
, pp. 4109-4118
-
-
Lech, M.1
Avila-Ferrufino, A.2
Allam, R.3
Segerer, S.4
Khandoga, A.5
Krom-bach, F.6
-
54
-
-
34447507719
-
Different roles of TiR8/Sigirr on tolllike receptor signaling in intrarenal antigen-presenting cells and tubular epithelial cells
-
Lech, M., Garlanda, C., Mantovani, A., Kirschning, C. J., Schlondorff, D., and Anders, H. J. (2007). Different roles of TiR8/Sigirr on tolllike receptor signaling in intrarenal antigen-presenting cells and tubular epithelial cells. Kidney Int. 72, 182-192.
-
(2007)
Kidney Int
, vol.72
, pp. 182-192
-
-
Lech, M.1
Garlanda, C.2
Mantovani, A.3
Kirschning, C.J.4
Schlondorff, D.5
Anders, H.J.6
-
55
-
-
49249109576
-
Tir8/Sigirr prevents murine lupus by suppressing the immunostimulatory effects of lupus autoantigens
-
Lech, M., Kulkarni, O. P., Pfeiffer, S., Savarese, E., Krug, A., Garlanda, C., et al. (2008). Tir8/Sigirr prevents murine lupus by suppressing the immunostimulatory effects of lupus autoantigens. J. Exp. Med. 205, 1879-1888.
-
(2008)
J. Exp. Med.
, vol.205
, pp. 1879-1888
-
-
Lech, M.1
Kulkarni, O.P.2
Pfeiffer, S.3
Savarese, E.4
Krug, A.5
Garlanda, C.6
-
56
-
-
77949846853
-
Lack of SIGIRR/TIR8 aggra-vateshydrocarbonoil-induced lupus nephritis
-
Lech, M., Skuginna, V., Kulkarni, O. P., Gong, J., Wei, T., Stark, R. W., et al. (2010). Lack of SIGIRR/TIR8 aggra-vateshydrocarbonoil-induced lupus nephritis. J. Pathol. 220, 596-607.
-
(2010)
J. Pathol.
, vol.220
, pp. 596-607
-
-
Lech, M.1
Skuginna, V.2
Kulkarni, O.P.3
Gong, J.4
Wei, T.5
Stark, R.W.6
-
57
-
-
26444571820
-
Renal-associated TLR2 mediates ischemia/reperfusion injury in the kidney
-
Leemans, J. C., Stokman, G., Claessen, N., Rouschop, K. M., Teske, G. J., Kirschning, C. J., et al. (2005). Renal-associated TLR2 mediates ischemia/reperfusion injury in the kidney. J. Clin. Invest. 115, 2894-2903.
-
(2005)
J. Clin. Invest.
, vol.115
, pp. 2894-2903
-
-
Leemans, J.C.1
Stokman, G.2
Claessen, N.3
Rouschop, K.M.4
Teske, G.J.5
Kirschning, C.J.6
-
58
-
-
18744388579
-
Modulation of toll-interleukin 1 receptor mediated signaling
-
Li, X., and Qin, J. (2005). Modulation of toll-interleukin 1 receptor mediated signaling. J. Mol. Med. 83, 258-266.
-
(2005)
J. Mol. Med.
, vol.83
, pp. 258-266
-
-
Li, X.1
Qin, J.2
-
59
-
-
77954662424
-
Toll-like receptor 9 signaling by CpG-B oligodeoxynu-cleotides induces an apoptotic pathway in human chronic lympho-cytic leukemia B cells
-
Liang, X., Moseman,E.A., Farrar,M.A., Bachanova,V., Weisdorf,D.J., Blazar, B. R., et al. (2010). Toll-like receptor 9 signaling by CpG-B oligodeoxynu-cleotides induces an apoptotic pathway in human chronic lympho-cytic leukemia B cells. Blood 115, 5041-5052.
-
(2010)
Blood
, vol.115
, pp. 5041-5052
-
-
Liang, X.1
Moseman, E.A.2
Farrar, M.A.3
Bachanova, V.4
Weisdorf, D.J.5
Blazar, B.R.6
-
60
-
-
78649884336
-
IL-33 family members and asthma - bridging innate and adaptive immune responses
-
Lloyd, C. M. (2010). IL-33 family members and asthma - bridging innate and adaptive immune responses. Curr. Opin. Immunol. 22, 800-806.
-
(2010)
Curr. Opin. Immunol.
, vol.22
, pp. 800-806
-
-
Lloyd, C.M.1
-
61
-
-
18144362027
-
Peptide-mediated interference of TIR domain dimeriza-tion in MyD88 inhibits interleukin-1-dependent activation of NF-{kappa}B
-
Loiarro, M., Sette, C., Gallo, G., Ciacci, A., Fanto, N., Mastroianni, D., et al. (2005). Peptide-mediated interference of TIR domain dimeriza-tion in MyD88 inhibits interleukin-1-dependent activation of NF-{kappa}B. J. Biol. Chem. 280, 15809-15814.
-
(2005)
J. Biol. Chem.
, vol.280
, pp. 15809-15814
-
-
Loiarro, M.1
Sette, C.2
Gallo, G.3
Ciacci, A.4
Fanto, N.5
Mastroianni, D.6
-
62
-
-
47949096781
-
Cancer-related inflammation
-
Mantovani, A., Allavena, P., Sica, A., and Balkwill, F. (2008). Cancer-related inflammation. Nature 454, 436-444.
-
(2008)
Nature
, vol.454
, pp. 436-444
-
-
Mantovani, A.1
Allavena, P.2
Sica, A.3
Balkwill, F.4
-
63
-
-
0034919056
-
Decoy receptors: a strategy to regulate inflammatory cytokines and chemokines
-
Mantovani, A., Locati, M., Vecchi, A., Sozzani, S., and Allavena, P. (2001). Decoy receptors: a strategy to regulate inflammatory cytokines and chemokines. Trends Immunol. 22, 328-336.
-
(2001)
Trends Immunol
, vol.22
, pp. 328-336
-
-
Mantovani, A.1
Locati, M.2
Vecchi, A.3
Sozzani, S.4
Allavena, P.5
-
64
-
-
34247891509
-
Immunologically active autoantigens: the role of tolllike receptors in the development of chronic inflammatory disease
-
Marshak-Rothstein, A., and Rifkin, I. R. (2007). Immunologically active autoantigens: the role of tolllike receptors in the development of chronic inflammatory disease. Annu. Rev. Immunol. 25, 419-441.
-
(2007)
Annu. Rev. Immunol.
, vol.25
, pp. 419-441
-
-
Marshak-Rothstein, A.1
Rifkin, I.R.2
-
65
-
-
82255191977
-
TLR-dependent T cell activation inautoimmunity
-
Mills, K. H. (2011). TLR-dependent T cell activation inautoimmunity.Nat. Rev. Immunol. 11, 807-822.
-
(2011)
Nat. Rev. Immunol.
, vol.11
, pp. 807-822
-
-
Mills, K.H.1
-
66
-
-
70350771183
-
The role of toll-like receptors in chronic B-cell malignancies
-
Muzio, M., Bertilaccio, M. T., Simon-etti, G.,Frenquelli, M.,and Caligaris-Cappio, F. (2009a). The role of toll-like receptors in chronic B-cell malignancies. Leuk. Lymphoma 50, 1573-1580.
-
(2009)
Leuk. Lymphoma
, vol.50
, pp. 1573-1580
-
-
Muzio, M.1
Bertilaccio, M.T.2
Simon-etti, G.3
Frenquelli, M.4
Caligaris-Cappio, F.5
-
67
-
-
58549120954
-
Expression and function of toll like receptors in chronic lymphocytic leukaemia cells
-
Muzio, M., Scielzo, C., Bertilaccio, M. T., Frenquelli, M., Ghia, P., and Caligaris-Cappio, F. (2009b). Expression and function of toll like receptors in chronic lymphocytic leukaemia cells. Br. J. Haematol. 144, 507-516.
-
(2009)
Br. J. Haematol.
, vol.144
, pp. 507-516
-
-
Muzio, M.1
Scielzo, C.2
Bertilaccio, M.T.3
Frenquelli, M.4
Ghia, P.5
Caligaris-Cappio, F.6
-
68
-
-
80052446462
-
MicroRNA in TLR signaling and endotoxin tolerance
-
Nahid,M.A., Satoh, M., and Chan,E.K. (2011). MicroRNA in TLR signaling and endotoxin tolerance. Cell. Mol. Immunol. 8, 388-403.
-
(2011)
Cell. Mol. Immunol.
, vol.8
, pp. 388-403
-
-
Nahid, M.A.1
Satoh, M.2
Chan, E.K.3
-
69
-
-
33646463163
-
An association study of asthma and related phenotypes with polymorphisms in negative regulator molecules of the TLR signaling pathway
-
Nakashima, K., Hirota, T., Obara, K., Shimizu, M., Jodo, A., Kameda, M., et al. (2006). An association study of asthma and related phenotypes with polymorphisms in negative regulator molecules of the TLR signaling pathway.J. Hum. Genet.51,284-291.
-
(2006)
J. Hum. Genet. 51
, pp. 284-291
-
-
Nakashima, K.1
Hirota, T.2
Obara, K.3
Shimizu, M.4
Jodo, A.5
Kameda, M.6
-
70
-
-
79952825184
-
The mechanism of excessive intestinal inflammation in necrotizing enterocoli-tis: an immature innate immune response
-
doi:10.1371/journal.pone.0017776
-
Nanthakumar, N., Meng, D., Goldstein, A. M., Zhu, W., Lu, L., Uauy, R., et al. (2011). The mechanism of excessive intestinal inflammation in necrotizing enterocoli-tis: an immature innate immune response. PLoS ONE 6, e17776. doi:10.1371/journal.pone.0017776
-
(2011)
PLoS ONE
, vol.6
-
-
Nanthakumar, N.1
Meng, D.2
Goldstein, A.M.3
Zhu, W.4
Lu, L.5
Uauy, R.6
-
71
-
-
0035817396
-
A critical role for interleukin 18 in primary and memory effector responses to Listeria monocytogenes that extends beyond its effects on Interferon gamma production
-
Neighbors, M., Xu, X., Barrat, F. J., Ruuls, S. R., Churakova, T., Debets, R., et al. (2001). A critical role for interleukin 18 in primary and memory effector responses to Listeria monocytogenes that extends beyond its effects on Interferon gamma production. J. Exp. Med. 194, 343-354.
-
(2001)
J. Exp. Med.
, vol.194
, pp. 343-354
-
-
Neighbors, M.1
Xu, X.2
Barrat, F.J.3
Ruuls, S.R.4
Churakova, T.5
Debets, R.6
-
72
-
-
70449709584
-
The Toll-IL-1R member Tir8/SIGIRR negatively regulates adaptive immunity against kidney grafts
-
Noris, M., Cassis, P., Azzollini, N., Cav-inato, R., Cugini, D., Casiraghi, F., et al. (2009). The Toll-IL-1R member Tir8/SIGIRR negatively regulates adaptive immunity against kidney grafts. J. Immunol. 183, 4249-4260.
-
(2009)
J. Immunol.
, vol.183
, pp. 4249-4260
-
-
Noris, M.1
Cassis, P.2
Azzollini, N.3
Cav-inato, R.4
Cugini, D.5
Casiraghi, F.6
-
73
-
-
40749097627
-
A dimer of the toll-like receptor 4 cytoplas-mic domain provides a specific scaffold for the recruitment of signalling adaptor proteins
-
doi:10.1371/journal.pone.0000788
-
Nunez Miguel, R., Wong, J., Westoll, J. F., Brooks, H. J., O'Neill, L. A., Gay, N. J., et al. (2007). A dimer of the toll-like receptor 4 cytoplas-mic domain provides a specific scaffold for the recruitment of signalling adaptor proteins. PLoS ONE 2, e788. doi:10.1371/journal.pone.0000788
-
(2007)
PLoS ONE
, vol.2
-
-
Nunez Miguel, R.1
Wong, J.2
Westoll, J.F.3
Brooks, H.J.4
O'Neill, L.A.5
Gay, N.J.6
-
74
-
-
30044442866
-
How toll-like receptors signal: what we know and what we don't know
-
O'Neill, L. A. (2006). How toll-like receptors signal: what we know and what we don't know. Curr. Opin. Immunol. 18, 3-9.
-
(2006)
Curr. Opin. Immunol.
, vol.18
, pp. 3-9
-
-
O'Neill, L.A.1
-
75
-
-
55149105005
-
The interleukin-1 receptor/toll-like receptor super-family: 10 years of progress
-
O'Neill, L. A. (2008). The interleukin-1 receptor/toll-like receptor super-family: 10 years of progress. Immunol. Rev. 226, 10-18.
-
(2008)
Immunol. Rev.
, vol.226
, pp. 10-18
-
-
O'Neill, L.A.1
-
76
-
-
27544465354
-
A distinct lineage of CD4 T cells regulates tissue inflammation by producing interleukin 17
-
Park, H., Li, Z., Yang, X. O., Chang, S. H., Nurieva, R., Wang, Y. H., et al. (2005). A distinct lineage of CD4 T cells regulates tissue inflammation by producing interleukin 17. Nat. Immunol. 6, 1133-1141.
-
(2005)
Nat. Immunol.
, vol.6
, pp. 1133-1141
-
-
Park, H.1
Li, Z.2
Yang, X.O.3
Chang, S.H.4
Nurieva, R.5
Wang, Y.H.6
-
77
-
-
1642498347
-
Unique pattern of expression and inhibition of IL-1 signaling by the IL-1 receptor family member TIR8/SIGIRR
-
Polentarutti, N., Rol, G. P., Muzio, M., Bosisio, D., Camnasio, M., Riva, F., et al. (2003). Unique pattern of expression and inhibition of IL-1 signaling by the IL-1 receptor family member TIR8/SIGIRR. Eur. Cytokine Netw. 14, 211-218.
-
(2003)
Eur. Cytokine Netw.
, vol.14
, pp. 211-218
-
-
Polentarutti, N.1
Rol, G.P.2
Muzio, M.3
Bosisio, D.4
Camnasio, M.5
Riva, F.6
-
78
-
-
79960036578
-
Whole-genome sequencing identifies recurrent mutations in chronic lym-phocytic leukaemia
-
Puente, X. S., Pinyol, M., Quesada, V., Conde, L., Ordonez, G. R., Vil-lamor, N., et al. (2011). Whole-genome sequencing identifies recurrent mutations in chronic lym-phocytic leukaemia. Nature 475, 101-105.
-
(2011)
Nature
, vol.475
, pp. 101-105
-
-
Puente, X.S.1
Pinyol, M.2
Quesada, V.3
Conde, L.4
Ordonez, G.R.5
Vil-lamor, N.6
-
79
-
-
21644477461
-
SIGIRR inhibits interleukin-1 receptor-and tolllike receptor 4-mediated signaling through different mechanisms
-
Qin, J., Qian, Y., Yao, J., Grace, C., and Li, X. (2005). SIGIRR inhibits interleukin-1 receptor-and tolllike receptor 4-mediated signaling through different mechanisms. J. Biol. Chem. 280, 25233-25241.
-
(2005)
J. Biol. Chem.
, vol.280
, pp. 25233-25241
-
-
Qin, J.1
Qian, Y.2
Yao, J.3
Grace, C.4
Li, X.5
-
80
-
-
79960073532
-
A trio of microRNAs that control toll-like receptor signalling
-
Quinn, S. R., and O'Neill, L. A. (2011). A trio of microRNAs that control toll-like receptor signalling. Int. Immunol. 23, 421-425.
-
(2011)
Int. Immunol.
, vol.23
, pp. 421-425
-
-
Quinn, S.R.1
O'Neill, L.A.2
-
81
-
-
34247187130
-
Reduced toll-like receptor 4 expression in children with asymptomatic bacteriuria
-
Ragnarsdottir, B., Samuelsson, M., Gustafsson, M. C., Leijonhufvud, I., Karpman, D., and Svanborg, C. (2007). Reduced toll-like receptor 4 expression in children with asymptomatic bacteriuria. J. Infect. Dis. 196, 475-484.
-
(2007)
J. Infect. Dis.
, vol.196
, pp. 475-484
-
-
Ragnarsdottir, B.1
Samuelsson, M.2
Gustafsson, M.C.3
Leijonhufvud, I.4
Karpman, D.5
Svanborg, C.6
-
83
-
-
3242664636
-
Recognition of commensal microflora by toll-like receptors is required for intestinal homeostasis
-
Rakoff-Nahoum, S., Paglino, J., Eslami-Varzaneh, F., Edberg, S., and Medzhitov, R. (2004). Recognition of commensal microflora by toll-like receptors is required for intestinal homeostasis. Cell 118, 229-241.
-
(2004)
Cell
, vol.118
, pp. 229-241
-
-
Rakoff-Nahoum, S.1
Paglino, J.2
Eslami-Varzaneh, F.3
Edberg, S.4
Medzhitov, R.5
-
84
-
-
66649113371
-
An autoinflammatory disease due to homozygous deletion of theIL1RNlocus
-
Reddy, S., Jia, S., Geoffrey, R., Lorier, R., Suchi, M., Broeckel, U., et al. (2009). An autoinflammatory disease due to homozygous deletion of theIL1RNlocus.N.Engl.J.Med.360, 2438-2444.
-
(2009)
N.Engl.J.Med
, vol.360
, pp. 2438-2444
-
-
Reddy, S.1
Jia, S.2
Geoffrey, R.3
Lorier, R.4
Suchi, M.5
Broeckel, U.6
-
85
-
-
68549126936
-
The expression pattern of TIR8 is conserved among vertebrates
-
Riva, F., Polentarutti, N., Tribbioli, G., Mantovani, A., Garlanda, C., and Turin, L. (2009). The expression pattern of TIR8 is conserved among vertebrates. Vet. Immunol. Immunopathol. 131, 44-49.
-
(2009)
Vet. Immunol. Immunopathol.
, vol.131
, pp. 44-49
-
-
Riva, F.1
Polentarutti, N.2
Tribbioli, G.3
Mantovani, A.4
Garlanda, C.5
Turin, L.6
-
86
-
-
84855854025
-
Mutations of NOTCH1 are an independent predictor of survival in chronic lymphocytic leukemia
-
Rossi, D., Rasi, S., Fabbri, G., Spina, V., Fangazio, M., Forconi, F., et al. (2012). Mutations of NOTCH1 are an independent predictor of survival in chronic lymphocytic leukemia. Blood 119, 521-529.
-
(2012)
Blood
, vol.119
, pp. 521-529
-
-
Rossi, D.1
Rasi, S.2
Fabbri, G.3
Spina, V.4
Fangazio, M.5
Forconi, F.6
-
87
-
-
33947545388
-
The toll-like receptor adaptor proteins MyD88 and Mal/TIRAP contribute to the inflammatory and destructive processes in a human model of rheumatoid arthritis
-
Sacre, S. M., Andreakos, E., Kiri-akidis, S., Amjadi, P., Lundberg, A., Giddins, G., et al. (2007). The toll-like receptor adaptor proteins MyD88 and Mal/TIRAP contribute to the inflammatory and destructive processes in a human model of rheumatoid arthritis. Am. J. Pathol. 170, 518-525.
-
(2007)
Am. J. Pathol.
, vol.170
, pp. 518-525
-
-
Sacre, S.M.1
Andreakos, E.2
Kiri-akidis, S.3
Amjadi, P.4
Lundberg, A.5
Giddins, G.6
-
88
-
-
77955350419
-
MyD88-mediated signaling prevents development of adenocarcinomas of the colon: role of interleukin 18
-
Salcedo, R., Worschech, A., Cardone, M., Jones, Y., Gyulai, Z., Dai, R. M., et al. (2010). MyD88-mediated signaling prevents development of adenocarcinomas of the colon: role of interleukin 18. J. Exp. Med. 207, 1625-1636.
-
(2010)
J. Exp. Med.
, vol.207
, pp. 1625-1636
-
-
Salcedo, R.1
Worschech, A.2
Cardone, M.3
Jones, Y.4
Gyulai, Z.5
Dai, R.M.6
-
89
-
-
84873208978
-
Association study of IRAK-M and SIGIRR genes with SLE in a large European-descent population
-
Sanchez, E., Garcia-Bermudez, M., Jimenez-Alonso, J., De Ramon, E., Sanchez-Roman, J., Ortego-Centeno, N., et al. (2012). Association study of IRAK-M and SIGIRR genes with SLE in a large European-descent population. Lupus 21, 1166-1171.
-
(2012)
Lupus
, vol.21
, pp. 1166-1171
-
-
Sanchez, E.1
Garcia-Bermudez, M.2
Jimenez-Alonso, J.3
De Ramon, E.4
Sanchez-Roman, J.5
Ortego-Centeno, N.6
-
90
-
-
42449117483
-
Requirement of toll-like receptor 7 for pristane-induced production of autoanti-bodies and development of murine lupus nephritis
-
Savarese, E., Steinberg, C., Pawar, R. D., Reindl, W., Akira, S., Anders, H. J., et al. (2008). Requirement of toll-like receptor 7 for pristane-induced production of autoanti-bodies and development of murine lupus nephritis. Arthritis Rheum. 58, 1107-1115.
-
(2008)
Arthritis Rheum
, vol.58
, pp. 1107-1115
-
-
Savarese, E.1
Steinberg, C.2
Pawar, R.D.3
Reindl, W.4
Akira, S.5
Anders, H.J.6
-
91
-
-
27744446058
-
IL-33, an interleukin-1-like cytokine that signals via the IL-1 receptor-related protein ST2 and induces T helper type 2-associated cytokines
-
Schmitz, J., Owyang, A., Oldham, E., Song, Y., Murphy, E., Mcclanahan, T. K., et al. (2005). IL-33, an interleukin-1-like cytokine that signals via the IL-1 receptor-related protein ST2 and induces T helper type 2-associated cytokines. Immunity 23, 479-490.
-
(2005)
Immunity
, vol.23
, pp. 479-490
-
-
Schmitz, J.1
Owyang, A.2
Oldham, E.3
Song, Y.4
Murphy, E.5
Mcclanahan, T.K.6
-
92
-
-
79955531653
-
Toll-like receptor signaling and SIGIRR in renal fibrosis upon unilateral ureteral obstruction
-
doi:10.1371/journal.pone.0019204
-
Skuginna, V., Lech, M., Allam, R., Ryu, M., Clauss, S., Susanti, H. E., et al. (2011). Toll-like receptor signaling and SIGIRR in renal fibrosis upon unilateral ureteral obstruction. PLoS ONE 6, e19204. doi:10.1371/journal.pone.0019204
-
(2011)
PLoS ONE
, vol.6
-
-
Skuginna, V.1
Lech, M.2
Allam, R.3
Ryu, M.4
Clauss, S.5
Susanti, H.E.6
-
93
-
-
77955275840
-
The pro-liferative response to CpG-ODN stimulation predicts PFS TTT and OS in patients with chronic lym-phocytic leukemia
-
Tarnani, M., Laurenti, L., Longo, P. G., Piccirillo, N., Gobessi, S., Man-nocci, A., et al. (2010). The pro-liferative response to CpG-ODN stimulation predicts PFS, TTT and OS in patients with chronic lym-phocytic leukemia. Leuk. Res. 34, 1189-1194.
-
(2010)
Leuk. Res.
, vol.34
, pp. 1189-1194
-
-
Tarnani, M.1
Laurenti, L.2
Longo, P.G.3
Piccirillo, N.4
Gobessi, S.5
Man-nocci, A.6
-
94
-
-
0033151633
-
Identification and characterization of SIGIRR, a molecule representing a novel subtype of the IL-1R superfamily
-
Thomassen, E., Renshaw, B. R., and Sims, J. E. (1999). Identification and characterization of SIGIRR, a molecule representing a novel subtype of the IL-1R superfamily. Cytokine 11, 389-399.
-
(1999)
Cytokine
, vol.11
, pp. 389-399
-
-
Thomassen, E.1
Renshaw, B.R.2
Sims, J.E.3
-
95
-
-
1842640230
-
Interleukin (IL)-1F6, IL-1F8, and IL-1F9 signal through IL-1Rrp2 and IL-1RAcP to activate the pathway leading to NF-kappaB and MAPKs
-
Towne,J. E., Garka,K.E.,Renshaw,B.R., Virca, G. D., and Sims, J. E. (2004). Interleukin (IL)-1F6, IL-1F8, and IL-1F9 signal through IL-1Rrp2 and IL-1RAcP to activate the pathway leading to NF-kappaB and MAPKs. J. Biol. Chem. 279, 13677-13688.
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 13677-13688
-
-
Towne, J.E.1
Garka, K.E.2
Renshaw, B.R.3
Virca, G.D.4
Sims, J.E.5
-
96
-
-
58549111588
-
Paneth cells directly sense gut commensals and maintain homeostasis at the intestinal host-microbial interface
-
Vaishnava, S., Behrendt, C. L., Ismail, A. S., Eckmann, L., and Hooper, L. V. (2008). Paneth cells directly sense gut commensals and maintain homeostasis at the intestinal host-microbial interface. Proc. Natl. Acad. Sci. U.S.A. 105, 20858-20863.
-
(2008)
Proc. Natl. Acad. Sci. U.S.A.
, vol.105
, pp. 20858-20863
-
-
Vaishnava, S.1
Behrendt, C.L.2
Ismail, A.S.3
Eckmann, L.4
Hooper, L.V.5
-
97
-
-
79952102031
-
Inflammasome activation and IL-1beta and IL-18 processing during infection
-
Van De Veerdonk, F. L., Netea, M. G., Dinarello, C. A., and Joosten, L. A. (2011). Inflammasome activation and IL-1beta and IL-18 processing during infection. Trends Immunol. 32, 110-116.
-
(2011)
Trends Immunol
, vol.32
, pp. 110-116
-
-
Van De Veerdonk, F.L.1
Netea, M.G.2
Dinarello, C.A.3
Joosten, L.A.4
-
98
-
-
84857098277
-
Role of toll interleukin-1 receptor (IL-1R) 8, a negative regulator of IL-1R/toll-like receptor signaling, in resistance to acute Pseudomonas aeruginosa lung infection
-
Veliz Rodriguez, T., Moalli, F., Polen-tarutti, N., Paroni, M., Bonavita, E., Anselmo, A., et al. (2012). Role of toll interleukin-1 receptor (IL-1R) 8, a negative regulator of IL-1R/toll-like receptor signaling, in resistance to acute Pseudomonas aeruginosa lung infection. Infect. Immun. 80, 100-109.
-
(2012)
Infect. Immun.
, vol.80
, pp. 100-109
-
-
Veliz Rodriguez, T.1
Moalli, F.2
Polen-tarutti, N.3
Paroni, M.4
Bonavita, E.5
Anselmo, A.6
-
99
-
-
84863539789
-
Immunobiotic Lacto-bacillus jensenii modulates the tolllike receptor 4-induced inflammatory response via negative regulation in porcine antigen-presenting cells
-
Villena, J., Suzuki, R., Fujie, H., Chiba, E., Takahashi, T., Tomosada, Y., et al. (2012). Immunobiotic Lacto-bacillus jensenii modulates the tolllike receptor 4-induced inflammatory response via negative regulation in porcine antigen-presenting cells. Clin. Vaccine Immunol. 19, 1038-1053.
-
(2012)
Clin. Vaccine Immunol.
, vol.19
, pp. 1038-1053
-
-
Villena, J.1
Suzuki, R.2
Fujie, H.3
Chiba, E.4
Takahashi, T.5
Tomosada, Y.6
-
100
-
-
0042733592
-
SIGIRR, a negative regulator of toll-like receptor-interleukin 1 receptor signaling
-
Wald, D., Qin, J., Zhao, Z., Qian, Y., Naramura, M., Tian, L., et al. (2003). SIGIRR, a negative regulator of toll-like receptor-interleukin 1 receptor signaling. Nat. Immunol. 4, 920-927.
-
(2003)
Nat. Immunol.
, vol.4
, pp. 920-927
-
-
Wald, D.1
Qin, J.2
Zhao, Z.3
Qian, Y.4
Naramura, M.5
Tian, L.6
-
101
-
-
77954214623
-
SIGIRR modulates the inflammatory response in the brain
-
Watson, M. B., Costello, D. A., Carney, D. G., Mcquillan, K., and Lynch, M.A. (2010). SIGIRR modulates the inflammatory response in the brain. Brain Behav. Immun. 24, 985-995.
-
(2010)
Brain Behav. Immun.
, vol.24
, pp. 985-995
-
-
Watson, M.B.1
Costello, D.A.2
Carney, D.G.3
Mcquillan, K.4
Lynch, M.A.5
-
102
-
-
34247175428
-
The Toll-interleukin-1 receptor member SIGIRR regulates colonic epithelial homeostasis, inflammation, and tumorigenesis
-
Xiao, H., Gulen, M. F., Qin, J., Yao, J., Bulek, K., Kish, D., et al. (2007). The Toll-interleukin-1 receptor member SIGIRR regulates colonic epithelial homeostasis, inflammation, and tumorigenesis. Immunity 26, 461-475.
-
(2007)
Immunity
, vol.26
, pp. 461-475
-
-
Xiao, H.1
Gulen, M.F.2
Qin, J.3
Yao, J.4
Bulek, K.5
Kish, D.6
-
103
-
-
77955485057
-
Loss of single immunoglob-ulin interlukin-1 receptor-related molecule leads to enhanced colonic polyposis in Apc(min) mice
-
Xiao, H., Yin, W., Khan, M. A., Gulen, M. F., Zhou, H., Sham, H. P., et al. (2010). Loss of single immunoglob-ulin interlukin-1 receptor-related molecule leads to enhanced colonic polyposis in Apc(min) mice. Gas-troenterology 139, 574-585.
-
(2010)
Gas-troenterology
, vol.139
, pp. 574-585
-
-
Xiao, H.1
Yin, W.2
Khan, M.A.3
Gulen, M.F.4
Zhou, H.5
Sham, H.P.6
-
104
-
-
0037112430
-
Microadenomatous lesions involving loss of Apc heterozygosity in the colon of adult Apc(Min/+) mice
-
Yamada, Y., Hata, K., Hirose, Y., Hara, A., Sugie, S., Kuno, T., et al. (2002). Microadenomatous lesions involving loss of Apc heterozygosity in the colon of adult Apc(Min/+) mice. Cancer Res. 62, 6367-6370.
-
(2002)
Cancer Res
, vol.62
, pp. 6367-6370
-
-
Yamada, Y.1
Hata, K.2
Hirose, Y.3
Hara, A.4
Sugie, S.5
Kuno, T.6
-
105
-
-
35348915412
-
IL-23 and the Th17 pathway promote inflammation and impair antifungal immune resistance
-
Zelante, T., De Luca, A., Bonifazi, P., Montagnoli, C., Bozza, S., Moretti, S., et al. (2007). IL-23 and the Th17 pathway promote inflammation and impair antifungal immune resistance. Eur. J. Immunol. 37, 2695-2706.
-
(2007)
Eur. J. Immunol.
, vol.37
, pp. 2695-2706
-
-
Zelante, T.1
De Luca, A.2
Bonifazi, P.3
Montagnoli, C.4
Bozza, S.5
Moretti, S.6
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