Role of proinflammatory cytokines IL-18 and IL-1β in bleomycin-induced lung injury in humans and mice

American Journal of Respiratory Cell and Molecular Biology

Volumn 41, Issue 6, 2009, Pages 661-670

  Hoshino, Tomoaki ^a,c   Okamoto, Masaki ^a   Sakazaki, Yuki ^a   Kato, Seiya ^b   Young, Howard A ^c   Aizawa, Hisamichi ^a  

^a KURUME UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^b UNIVERSITY OF THE RYUKYUS   (Japan)

^c NATIONAL CANCER INSTITUTE   (United States)

Author keywords

Bleomycin; Cytokine; Lung injury; Mouse model

Indexed keywords

BLEOMYCIN; INTERLEUKIN 18; INTERLEUKIN 18 RECEPTOR ALPHA; INTERLEUKIN 1BETA; INTERLEUKIN 1BETA CONVERTING ENZYME; MESSENGER RNA;

ADULT; AGED; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CD3+ T LYMPHOCYTE; CLINICAL ARTICLE; CONTROLLED STUDY; FEMALE; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; LUNG FIBROSIS; LUNG INJURY; MALE; MOUSE; NEUTROPHIL; NONHUMAN; PNEUMONIA;

ACUTE LUNG INJURY; AGED; ANIMALS; ANTIBIOTICS, ANTINEOPLASTIC; BLEOMYCIN; CASPASE 1; DISEASE MODELS, ANIMAL; FEMALE; HUMANS; INFLAMMATION MEDIATORS; INJECTIONS, INTRAVENOUS; INTERLEUKIN-18; INTERLEUKIN-18 RECEPTOR ALPHA SUBUNIT; INTERLEUKIN-1BETA; LUNG; MALE; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MIDDLE AGED; NEUTROPHILS; RNA, MESSENGER;

MUS;

EID: 70949103587     PISSN: 10441549     EISSN: None     Source Type: Journal    
DOI: 10.1165/rcmb.2008-0182OC     Document Type: Article

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