Mitochondrial dysfunction in bipolar disorder: Evidence, pathophysiology and translational implications

Neuroscience and Biobehavioral Reviews

Volumn 68, Issue , 2016, Pages 694-713

  Scaini, Giselli ^a,b   Rezin, Gislaine T ^c   Carvalho, Andre F ^d   Streck, Emilio L ^b   Berk, Michael ^e,f   Quevedo, João ^a,c,g  

^a UNIVERSITY OF TEXAS MEDICAL SCHOOL   (United States)

^b UNIVERSIDADE DO EXTREMO SUL CATARINENSE   (Brazil)

^c UNIVERSITY OF SOUTHERN SANTA CATARINA   (Brazil)

^d FEDERAL UNIVERSITY OF CEARÁ   (Brazil)

^e DEAKIN UNIVERSITY   (Australia)

^f UNIVERSITY OF MELBOURNE   (Australia)

^g UNIVERSITY OF TEXAS   (United States)

Author keywords

Apoptosis; Bipolar disorder; Depression; Inflammation; Mania; Mitochondria; Mitochondrial dysfunction; Neurogenesis; Oxidative stress

Indexed keywords

ACETYLCYSTEINE; LEVACECARNINE; LITHIUM; MESSENGER RNA; MITOCHONDRIAL DNA; OMEGA 3 FATTY ACID; PLACEBO; THIOCTIC ACID; UBIDECARENONE; VALPROIC ACID;

BIPOLAR DISORDER; CELL DEATH; CELL SURVIVAL; COGNITIVE DEFECT; DISORDERS OF MITOCHONDRIAL FUNCTIONS; DNA POLYMORPHISM; DOWN REGULATION; DRUG EFFICACY; ENERGY METABOLISM; HIGH ENERGY PHOSPHATE; HUMAN; MAINTENANCE THERAPY; MITOCHONDRIAL DYNAMICS; MITOCHONDRIAL RESPIRATION; NERVE CELL PLASTICITY; NONHUMAN; OXIDATIVE STRESS; PATHOGENESIS; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL (TOPIC); REVIEW; SIGNAL TRANSDUCTION; GENETIC POLYMORPHISM; MITOCHONDRION;

BIPOLAR DISORDER; ENERGY METABOLISM; MITOCHONDRIA; POLYMORPHISM, GENETIC;

EID: 84978289214     PISSN: 01497634     EISSN: 18737528     Source Type: Journal    
DOI: 10.1016/j.neubiorev.2016.06.040     Document Type: Review

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