메뉴 건너뛰기




Volumn 69, Issue 10, 2011, Pages 980-988

Perturbation in mitochondrial network dynamics and in complex I dependent cellular respiration in schizophrenia

Author keywords

Antipsychotic drugs; bipolar disorder; dopamine; mitochondrial network dynamics; mitochondrial respiration; schizophrenia

Indexed keywords

CHLORPROMAZINE; CLOZAPINE; DOPAMINE; HALOPERIDOL; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE DEHYDROGENASE (UBIQUINONE); SULPIRIDE;

EID: 79955476771     PISSN: 00063223     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.biopsych.2011.01.010     Document Type: Article
Times cited : (113)

References (84)
  • 1
    • 0028137817 scopus 로고
    • Mitochondria buffer physiological calcium loads in cultured rat dorsal root ganglion neurons
    • J.L. Werth, and S.A. Thayer Mitochondria buffer physiological calcium loads in cultured rat dorsal root ganglion neurons J Neurosci 14 1994 348 356 (Pubitemid 24022122)
    • (1994) Journal of Neuroscience , vol.14 , Issue.1 , pp. 348-356
    • Werth, J.L.1    Thayer, S.A.2
  • 2
    • 0038391398 scopus 로고    scopus 로고
    • Signaling from synapse to nucleus: The logic behind the mechanisms
    • DOI 10.1016/S0959-4388(03)00076-X
    • K. Deisseroth, P.G. Mermelstein, H. Xia, and R.W. Tsien Signaling from synapse to nucleus: The logic behind the mechanisms Curr Opin Neurobiol 13 2003 354 365 (Pubitemid 36805579)
    • (2003) Current Opinion in Neurobiology , vol.13 , Issue.3 , pp. 354-365
    • Deisseroth, K.1    Mermelstein, P.G.2    Xia, H.3    Tsien, R.W.4
  • 3
    • 0037427415 scopus 로고    scopus 로고
    • Mitochondrial potassium channels and uncoupling proteins in synaptic plasticity and neuronal cell death
    • DOI 10.1016/S0006-291X(03)00627-2
    • M.P. Mattson, and D. Liu Mitochondrial potassium channels and uncoupling proteins in synaptic plasticity and neuronal cell death Biochem Biophys Res Commun 304 2003 539 549 (Pubitemid 36506527)
    • (2003) Biochemical and Biophysical Research Communications , vol.304 , Issue.3 , pp. 539-549
    • Mattson, M.P.1    Liu, D.2
  • 4
    • 77953912359 scopus 로고    scopus 로고
    • Calcium clearance and its energy requirements in cerebellar neurons
    • M.V. Ivannikov, M. Sugimori, and R.R. Llinas Calcium clearance and its energy requirements in cerebellar neurons Cell Calcium 47 2010 507 513
    • (2010) Cell Calcium , vol.47 , pp. 507-513
    • Ivannikov, M.V.1    Sugimori, M.2    Llinas, R.R.3
  • 5
    • 0016688906 scopus 로고
    • On the role of mitochondria in transmitter release from motor nerve terminals
    • E. Alnaes, and R. Rahamimoff On the role of mitochondria in transmitter release from motor nerve terminals J Physiol 248 1975 285 306
    • (1975) J Physiol , vol.248 , pp. 285-306
    • Alnaes, E.1    Rahamimoff, R.2
  • 6
    • 0030891028 scopus 로고    scopus 로고
    • Mitochondrial involvement in post-tetanic potentiation of synaptic transmission
    • DOI 10.1016/S0896-6273(00)81248-9
    • Y. Tang, and R.S. Zucker Mitochondrial involvement in post-tetanic potentiation of synaptic transmission Neuron 18 1997 483 491 (Pubitemid 27138795)
    • (1997) Neuron , vol.18 , Issue.3 , pp. 483-491
    • Tang, Y.-G.1    Zucker, R.S.2
  • 8
    • 0029788243 scopus 로고    scopus 로고
    • Mitochondrial depolarization in glutamate-stimulated neurons: An early signal specific to excitotoxin exposure
    • R.J. White, and I.J. Reynolds Mitochondrial depolarization in glutamate-stimulated neurons: An early signal specific to excitotoxin exposure J Neurosci 16 1996 5688 5697 (Pubitemid 26293392)
    • (1996) Journal of Neuroscience , vol.16 , Issue.18 , pp. 5688-5697
    • White, R.J.1    Reynolds, I.J.2
  • 10
    • 50949084911 scopus 로고    scopus 로고
    • Dopamine inhibits mitochondrial motility in hippocampal neurons
    • S. Chen, G.C. Owens, and D.B. Edelman Dopamine inhibits mitochondrial motility in hippocampal neurons PLoS ONE 3 2008 e2804
    • (2008) PLoS ONE , vol.3 , pp. 2804
    • Chen, S.1    Owens, G.C.2    Edelman, D.B.3
  • 11
    • 38549125376 scopus 로고    scopus 로고
    • Dopamine modulates mitochondrial function in viable SH-SY5Y cells possibly via its interaction with complex I: Relevance to dopamine pathology in schizophrenia
    • DOI 10.1016/j.bbabio.2007.10.006, PII S0005272807002320
    • H. Brenner-Lavie, E. Klein, R. Zuk, H. Gazawi, P. Ljubuncic, and D. Ben-Shachar Dopamine modulates mitochondrial function in viable SH-SY5Y cells possibly via its interaction with complex I: Relevance to dopamine pathology in schizophrenia Biochim Biophys Acta 1777 2008 173 185 (Pubitemid 351162862)
    • (2008) Biochimica et Biophysica Acta - Bioenergetics , vol.1777 , Issue.2 , pp. 173-185
    • Brenner-Lavie, H.1    Klein, E.2    Zuk, R.3    Gazawi, H.4    Ljubuncic, P.5    Ben-Shachar, D.6
  • 12
    • 67349190515 scopus 로고    scopus 로고
    • Mitochondrial complex I as a novel target for intraneuronal DA: Modulation of respiration in intact cells
    • H. Brenner-Lavie, E. Klein, and D. Ben-Shachar Mitochondrial complex I as a novel target for intraneuronal DA: Modulation of respiration in intact cells Biochem Pharmacol 78 2009 85 95
    • (2009) Biochem Pharmacol , vol.78 , pp. 85-95
    • Brenner-Lavie, H.1    Klein, E.2    Ben-Shachar, D.3
  • 13
    • 0028813395 scopus 로고
    • Dopamine neurotoxicity: Inhibition of mitochondrial respiration
    • D. Ben-Shachar, R. Zuk, and Y. Glinka Dopamine neurotoxicity: Inhibition of mitochondrial respiration J Neurochem 64 1995 718 723
    • (1995) J Neurochem , vol.64 , pp. 718-723
    • Ben-Shachar, D.1    Zuk, R.2    Glinka, Y.3
  • 14
    • 60049097207 scopus 로고    scopus 로고
    • Expression of mitochondrial complex I subunit gene NDUFV2 in the lymphoblastoid cells derived from patients with bipolar disorder and schizophrenia
    • S. Washizuka, K. Iwamoto, C. Kakiuchi, M. Bundo, and T. Kato Expression of mitochondrial complex I subunit gene NDUFV2 in the lymphoblastoid cells derived from patients with bipolar disorder and schizophrenia Neurosci Res 63 2009 199 204
    • (2009) Neurosci Res , vol.63 , pp. 199-204
    • Washizuka, S.1    Iwamoto, K.2    Kakiuchi, C.3    Bundo, M.4    Kato, T.5
  • 16
    • 69249231188 scopus 로고    scopus 로고
    • Mitochondrial complex I subunits are altered in rats with neonatal ventral hippocampal damage but not in rats exposed to oxygen restriction at neonatal age
    • D. Ben-Shachar, C. Nadri, R. Karry, and G. Agam Mitochondrial complex I subunits are altered in rats with neonatal ventral hippocampal damage but not in rats exposed to oxygen restriction at neonatal age J Mol Neurosci 38 2009 143 151
    • (2009) J Mol Neurosci , vol.38 , pp. 143-151
    • Ben-Shachar, D.1    Nadri, C.2    Karry, R.3    Agam, G.4
  • 18
    • 1642352614 scopus 로고    scopus 로고
    • Mitochondrial complex I subunits expression is altered in schizophrenia: A postmortem study
    • DOI 10.1016/j.biopsych.2003.12.012, PII S0006322304000083
    • R. Karry, E. Klein, and D. Ben Shachar Mitochondrial complex I subunits expression is altered in schizophrenia: A postmortem study Biol Psychiatry 55 2004 676 684 (Pubitemid 38376178)
    • (2004) Biological Psychiatry , vol.55 , Issue.7 , pp. 676-684
    • Karry, R.1    Klein, E.2    Shachar, D.B.3
  • 23
    • 0035109413 scopus 로고    scopus 로고
    • Mitochondrial DNA polymorphisms in bipolar disorder
    • DOI 10.1016/S0165-0327(99)00173-1, PII S0165032799001731
    • T. Kato, H. Kunugi, S. Nanko, and N. Kato Mitochondrial DNA polymorphisms in bipolar disorder J Affect Disord 62 2001 151 164 (Pubitemid 32167082)
    • (2001) Journal of Affective Disorders , vol.62 , Issue.3 , pp. 151-164
    • Kato, T.1    Kunugi, H.2    Nanko, S.3    Kato, N.4
  • 24
    • 56649111125 scopus 로고    scopus 로고
    • Neuroanatomical pattern of mitochondrial complex I pathology varies between schizophrenia, bipolar disorder and major depression
    • D. Ben-Shachar, and R. Karry Neuroanatomical pattern of mitochondrial complex I pathology varies between schizophrenia, bipolar disorder and major depression PLoS ONE 3 2008 e3676
    • (2008) PLoS ONE , vol.3 , pp. 3676
    • Ben-Shachar, D.1    Karry, R.2
  • 25
    • 77950575478 scopus 로고    scopus 로고
    • Mitochondrial complex I activity and oxidative damage to mitochondrial proteins in the prefrontal cortex of patients with bipolar disorder
    • A.C. Andreazza, L. Shao, J.F. Wang, and L.T. Young Mitochondrial complex I activity and oxidative damage to mitochondrial proteins in the prefrontal cortex of patients with bipolar disorder Arch Gen Psychiatry 67 2010 360 368
    • (2010) Arch Gen Psychiatry , vol.67 , pp. 360-368
    • Andreazza, A.C.1    Shao, L.2    Wang, J.F.3    Young, L.T.4
  • 27
    • 0029848373 scopus 로고    scopus 로고
    • Mitochondrial involvement in schizophrenia and other functional psychoses
    • DOI 10.1007/BF02532409
    • S.A. Whatley, D. Curi, and R.M. Marchbanks Mitochondrial involvement in schizophrenia and other functional psychoses Neuroch Res 21 1996 995 1004 (Pubitemid 26349764)
    • (1996) Neurochemical Research , vol.21 , Issue.9 , pp. 995-1004
    • Whatley, S.A.1    Curti, D.2    Marchbanks, R.M.3
  • 29
    • 0036430378 scopus 로고    scopus 로고
    • State-dependent alterations in mitochondrial complex I activity in platelets: A potential peripheral marker for schizophrenia
    • DOI 10.1038/sj.mp.4001116
    • N. Dror, E. Klein, R. Karry, A. Sheinkman, Z. Kirsh, and M. Mazor State dependent alterations in mitochondrial complex I activity in platelets: A potential peripheral marker for schizophrenia Mol Psychiatry 7 2002 995 1001 (Pubitemid 35333055)
    • (2002) Molecular Psychiatry , vol.7 , Issue.9 , pp. 995-1001
    • Dror, N.1    Klein, E.2    Karry, R.3    Sheinkman, A.4    Kirsh, Z.5    Mazor, M.6    Tzukerman, M.7    Ben-Shachar, D.8
  • 30
    • 33748943677 scopus 로고    scopus 로고
    • Microarray analysis reveals distinct gene expression patterns in the mouse cortex following chronic neuroleptic and stimulant treatment: Implications for body weight changes
    • DOI 10.1007/s00702-005-0425-y
    • C. Mehler-Wex, E. Grunblatt, S. Zeiske, G. Gille, D. Rausch, A. Warnke, and M. Gerlach Microarray analysis reveals distinct gene expression patterns in the mouse cortex following chronic neuroleptic and stimulant treatment: Implications for body weight changes J Neural Transm 113 2006 1383 1393 (Pubitemid 44435876)
    • (2006) Journal of Neural Transmission , vol.113 , Issue.10 , pp. 1383-1393
    • Mehler-Wex, C.1    Grunblatt, E.2    Zeiske, S.3    Gille, G.4    Rausch, D.5    Warnke, A.6    Gerlach, M.7
  • 33
    • 0035146891 scopus 로고    scopus 로고
    • Mitochondrial filaments and clusters as intracellular power-transmitting cables
    • DOI 10.1016/S0968-0004(00)01735-7, PII S0968000400017357
    • V.P. Skulachev Mitochondrial filaments and clusters as intracellular power-transmitting cables Trends Biochem Sci 26 2001 23 29 (Pubitemid 32124706)
    • (2001) Trends in Biochemical Sciences , vol.26 , Issue.1 , pp. 23-29
    • Skulachev, V.P.1
  • 34
    • 77955638748 scopus 로고    scopus 로고
    • Respiratory chain complexes in dynamic mitochondria display a patchy distribution in life cells
    • B. Muster, W. Kohl, I. Wittig, V. Strecker, F. Joos, and W. Haase Respiratory chain complexes in dynamic mitochondria display a patchy distribution in life cells PLoS ONE 5 2010 e11910
    • (2010) PLoS ONE , vol.5 , pp. 11910
    • Muster, B.1    Kohl, W.2    Wittig, I.3    Strecker, V.4    Joos, F.5    Haase, W.6
  • 36
    • 76749113759 scopus 로고    scopus 로고
    • Response of mitochondrial fusion and fission protein gene expression to exercise in rat skeletal muscle
    • H. Ding, N. Jiang, H. Liu, X. Liu, D. Liu, and F. Zhao Response of mitochondrial fusion and fission protein gene expression to exercise in rat skeletal muscle Biochim Biophys Acta 1800 2010 250 256
    • (2010) Biochim Biophys Acta , vol.1800 , pp. 250-256
    • Ding, H.1    Jiang, N.2    Liu, H.3    Liu, X.4    Liu, D.5    Zhao, F.6
  • 37
    • 45349089531 scopus 로고    scopus 로고
    • Molecular machinery of mitochondrial fusion and fission
    • B. Westermann Molecular machinery of mitochondrial fusion and fission J Biol Chem 283 2008 13501 13505
    • (2008) J Biol Chem , vol.283 , pp. 13501-13505
    • Westermann, B.1
  • 38
    • 58949099388 scopus 로고    scopus 로고
    • Effects of overexpression of huntingtin proteins on mitochondrial integrity
    • H. Wang, P.J. Lim, M. Karbowski, and M.J. Monteiro Effects of overexpression of huntingtin proteins on mitochondrial integrity Hum Mol Genet 18 2009 737 752
    • (2009) Hum Mol Genet , vol.18 , pp. 737-752
    • Wang, H.1    Lim, P.J.2    Karbowski, M.3    Monteiro, M.J.4
  • 41
    • 55749090654 scopus 로고    scopus 로고
    • The Parkinson's disease genes pink1 and Parkin promote mitochondrial fission and/or inhibit fusion in Drosophila
    • H. Deng, M.W. Dodson, H. Huang, and M. Guo The Parkinson's disease genes pink1 and Parkin promote mitochondrial fission and/or inhibit fusion in Drosophila Proc Natl Acad Sci U S A 105 2008 14503 14508
    • (2008) Proc Natl Acad Sci U S A , vol.105 , pp. 14503-14508
    • Deng, H.1    Dodson, M.W.2    Huang, H.3    Guo, M.4
  • 44
    • 67650732998 scopus 로고    scopus 로고
    • Impaired balance of mitochondrial fission and fusion in Alzheimer's disease
    • X. Wang, B. Su, H.G. Lee, X. Li, G. Perry, M.A. Smith, and X. Zhu Impaired balance of mitochondrial fission and fusion in Alzheimer's disease J Neurosci 29 2009 9090 9103
    • (2009) J Neurosci , vol.29 , pp. 9090-9103
    • Wang, X.1    Su, B.2    Lee, H.G.3    Li, X.4    Perry, G.5    Smith, M.A.6    Zhu, X.7
  • 45
    • 68249087424 scopus 로고    scopus 로고
    • Mitochondrial fission factor Drp1 is essential for embryonic development and synapse formation in mice
    • N. Ishihara, M. Nomura, A. Jofuku, H. Kato, S.O. Suzuki, and K. Masuda Mitochondrial fission factor Drp1 is essential for embryonic development and synapse formation in mice Nat Cell Biol 11 2009 958 966
    • (2009) Nat Cell Biol , vol.11 , pp. 958-966
    • Ishihara, N.1    Nomura, M.2    Jofuku, A.3    Kato, H.4    Suzuki, S.O.5    Masuda, K.6
  • 47
    • 0032799751 scopus 로고    scopus 로고
    • Smoking disturbs mitochondrial respiratory chain function and enhances lipid peroxidation on human circulating lymphocytes
    • DOI 10.1093/carcin/20.7.1331
    • O. Miro, J.R. Alonso, D. Jarreta, J. Casademont, A. Urbano-Marquez, and F. Cardellach Smoking disturbs mitochondrial respiratory chain function and enhances lipid peroxidation on human circulating lymphocytes Carcinogenesis 20 1999 1331 1336 (Pubitemid 29341457)
    • (1999) Carcinogenesis , vol.20 , Issue.7 , pp. 1331-1336
    • Miro, O.1    Alonso, J.R.2    Jarreta, D.3    Casademont, J.4    Urbano-Marquez, A.5    Cardellach, F.6
  • 48
    • 0029935370 scopus 로고    scopus 로고
    • Use of polarography to detect respiration defects in cell cultures
    • DOI 10.1016/S0076-6879(96)64043-9
    • G. Hofhaus, R.M. Shakeley, and G. Attardi Use of polarography to detect respiration defects in cell cultures Methods Enzymol 264 1996 476 483 (Pubitemid 26089332)
    • (1996) Methods in Enzymology , vol.264 , pp. 476-483
    • Hofhaus, G.1    Shakeley, R.M.2    Attardi, G.3
  • 49
    • 0025471534 scopus 로고
    • Rapid isolation of metabolically active mitochondria from rat brain and subregions using percoll density gradient centrifugation
    • N.R. Sims Rapid isolation of metabolically active mitochondria from rat brain and subregions using Percoll density gradient centrifugation J Neurochem 55 1990 698 707 (Pubitemid 120021648)
    • (1990) Journal of Neurochemistry , vol.55 , Issue.2 , pp. 698-707
    • Sims, N.R.1
  • 50
    • 0018113861 scopus 로고
    • Preparation and properties of the enzyme complexes of the mitochondrial oxidative phosphorylation system
    • Y. Hatefi Preparation and properties of the enzyme complexes of the mitochondrial oxidative phosphorylation system Methods Enzymol 53 1978 30-10
    • (1978) Methods Enzymol , vol.53
    • Hatefi, Y.1
  • 51
    • 0001889165 scopus 로고
    • Subfractionation of mitochondria and isolation of the proteins of oxidative phosphorylation
    • C.I. Ragan, M.T. Wilson, V.M. Darley-Usmar, and P.N. Lowe Subfractionation of mitochondria and isolation of the proteins of oxidative phosphorylation V.M. Darely-Usmar, D. Rickwood, M.M. Wilson, Mitochondria, a Practical Approach 1987 IRL Press London 79 112
    • (1987) Mitochondria, a Practical Approach , pp. 79-112
    • Ragan, C.I.1    Wilson, M.T.2    Darley-Usmar, V.M.3    Lowe, P.N.4
  • 52
    • 0035108147 scopus 로고    scopus 로고
    • Protein thiol oxidation by haloperidol results in inhibition of mitochondrial complex I in brain regions: Comparison with atypical antipsychotics
    • DOI 10.1016/S0197-0186(00)00108-X, PII S019701860000108X
    • S. Balijepalli, R.S. Kenchappa, M.R. Boyd, and V. Ravindranath Protein thiol oxidation by haloperidol results in inhibition of mitochondrial complex I in brain regions: Comparison with atypical antipsychotics Neurochem Int 38 2001 425 435 (Pubitemid 32166900)
    • (2001) Neurochemistry International , vol.38 , Issue.5 , pp. 425-435
    • Balijepalli, S.1    Kenchappa, R.S.2    Boyd, M.R.3    Ravindranath, V.4
  • 53
    • 0034601620 scopus 로고    scopus 로고
    • The Stanley Foundation brain collection and Neuropathology Consortium
    • DOI 10.1016/S0920-9964(99)00192-9, PII S0920996499001929
    • E.F. Torrey, M. Webster, M. Knable, N. Johnston, and R.H. Yolken The Stanley Foundation Brain Collection and neuropathology consortium Schizophr Res 44 2000 151 155 (Pubitemid 30411930)
    • (2000) Schizophrenia Research , vol.44 , Issue.2 , pp. 151-155
    • Torrey, E.F.1    Webster, M.2    Knable, M.3    Johnston, N.4    Yolken, R.H.5
  • 54
    • 4644327947 scopus 로고    scopus 로고
    • Highly selective and prolonged depletion of mitochondrial glutathione in astrocytes markedly increases sensitivity to peroxynitrite
    • DOI 10.1523/JNEUROSCI.1103-04.2004
    • H. Muyderman, M. Nilsson, and N.R. Sims Highly selective and prolonged depletion of mitochondrial glutathione in astrocytes markedly increases sensitivity to peroxynitrite J Neurosci 24 2004 8019 8028 (Pubitemid 39280821)
    • (2004) Journal of Neuroscience , vol.24 , Issue.37 , pp. 8019-8028
    • Muyderman, H.1    Nilsson, M.2    Sims, N.R.3
  • 55
    • 0023718495 scopus 로고
    • Coupling membranes as energy-transmitting cables: I. Filamentous mitochondria in fibroblasts and mitochondrial clusters in cardiomyocytes
    • A.A. Amchenkova, L.E. Bakeeva, Y.S. Chentsov, V.P. Skulachev, and D.B. Zorov Coupling membranes as energy-transmitting cables I. Filamentous mitochondria in fibroblasts and mitochondrial clusters in cardiomyocytes J Cell Biol 107 1988 481 495
    • (1988) J Cell Biol , vol.107 , pp. 481-495
    • Amchenkova, A.A.1    Bakeeva, L.E.2    Chentsov, Y.S.3    Skulachev, V.P.4    Zorov, D.B.5
  • 57
    • 0001720216 scopus 로고
    • Studies on the respiratory chain-linked reduced nicotinamide adenine dinucleotide dehydrogenase: VII. "Labile" sulfide groups in the dehydrogenase and in related proteins
    • C.J. Lusty, J.M. Machinist, and T.P. Singer Studies on the respiratory chain-linked reduced nicotinamide adenine dinucleotide dehydrogenase VII. "Labile" sulfide groups in the dehydrogenase and in related proteins J Biol Chem 240 1965 1804 1810
    • (1965) J Biol Chem , vol.240 , pp. 1804-1810
    • Lusty, C.J.1    Machinist, J.M.2    Singer, T.P.3
  • 58
    • 0015230446 scopus 로고
    • EPR studies on the ironsulfur centers of DPNH dehydrogenase during the redox cycle of the enzyme
    • M. Gutman, and T.P. Singer EPR studies on the ironsulfur centers of DPNH dehydrogenase during the redox cycle of the enzyme Biochem Biophys Res Commun 44 1971 1572 1578
    • (1971) Biochem Biophys Res Commun , vol.44 , pp. 1572-1578
    • Gutman, M.1    Singer, T.P.2
  • 59
    • 2342573633 scopus 로고    scopus 로고
    • Dopamine toxicity involves mitochondrial complex I inhibition: Implications to dopamine-related neuropsychiatric disorders
    • DOI 10.1016/j.bcp.2004.02.015, PII S0006295204001303
    • D. Ben-Shachar, R. Zuk, H. Gazawi, and P. Ljubuncic Dopamine toxicity involves mitochondrial complex I inhibition: Implications to dopamine-related neuropsychiatric disorders Biochem Pharmacol 67 2004 1965 1974 (Pubitemid 38591384)
    • (2004) Biochemical Pharmacology , vol.67 , Issue.10 , pp. 1965-1974
    • Ben-Shachar, D.1    Zuk, R.2    Gazawi, H.3    Ljubuncic, P.4
  • 60
    • 0036430378 scopus 로고    scopus 로고
    • State-dependent alterations in mitochondrial complex I activity in platelets: A potential peripheral marker for schizophrenia
    • DOI 10.1038/sj.mp.4001116
    • N. Dror, E. Klein, R. Karry, A. Sheinkman, Z. Kirsh, and M. Mazor State-dependent alterations in mitochondrial complex I activity in platelets: A potential peripheral marker for schizophrenia Mol Psychiatry 7 2002 995 1001 (Pubitemid 35333055)
    • (2002) Molecular Psychiatry , vol.7 , Issue.9 , pp. 995-1001
    • Dror, N.1    Klein, E.2    Karry, R.3    Sheinkman, A.4    Kirsh, Z.5    Mazor, M.6    Tzukerman, M.7    Ben-Shachar, D.8
  • 61
    • 56349085087 scopus 로고    scopus 로고
    • Insulin, IGF-1, and muscarinic agonists modulate schizophrenia-associated genes in human neuroblastoma cells
    • C.A. Altar, R.A. Hunt, L.W. Jurata, M.J. Webster, E. Derby, and P. Gallagher Insulin, IGF-1, and muscarinic agonists modulate schizophrenia- associated genes in human neuroblastoma cells Biol Psychiatry 64 2008 1077 1087
    • (2008) Biol Psychiatry , vol.64 , pp. 1077-1087
    • Altar, C.A.1    Hunt, R.A.2    Jurata, L.W.3    Webster, M.J.4    Derby, E.5    Gallagher, P.6
  • 62
    • 0347510636 scopus 로고    scopus 로고
    • The neonatal ventral hippocampal lesion model of schizophrenia: Effects on dopamine and GABA mRNA markers in the rat midbrain
    • DOI 10.1111/j.1460-9568.2003.03047.x
    • B.K. Lipska, D.N. Lerman, Z.Z. Khaing, and D.R. Weinberger The neonatal ventral hippocampal lesion model of schizophrenia: Effects on dopamine and GABA mRNA markers in the rat midbrain Eur J Neurosci 18 2003 3097 3104 (Pubitemid 38021551)
    • (2003) European Journal of Neuroscience , vol.18 , Issue.11 , pp. 3097-3104
    • Lipska, B.K.1    Lerman, D.N.2    Khaing, Z.Z.3    Weinberger, D.R.4
  • 63
  • 66
    • 20244381365 scopus 로고    scopus 로고
    • Nuclear gene OPA1, encoding a mitochondrial dynamin-related protein, is mutated in dominant optic atrophy
    • C. Delettre, G. Lenaers, J.M. Griffoin, N. Gigarel, C. Lorenzo, and P. Belenguer Nuclear gene OPA1, encoding a mitochondrial dynamin-related protein, is mutated in dominant optic atrophy Nat Genet 26 2000 207 210
    • (2000) Nat Genet , vol.26 , pp. 207-210
    • Delettre, C.1    Lenaers, G.2    Griffoin, J.M.3    Gigarel, N.4    Lorenzo, C.5    Belenguer, P.6
  • 67
    • 77951235489 scopus 로고    scopus 로고
    • Perturbations in mitochondrial dynamics induced by human mutant PINK1 can be rescued by the mitochondrial division inhibitor mdivi-1
    • M. Cui, X. Tang, W.V. Christian, Y. Yoon, and K. Tieu Perturbations in mitochondrial dynamics induced by human mutant PINK1 can be rescued by the mitochondrial division inhibitor mdivi-1 J Biol Chem 285 2010 11740 11752
    • (2010) J Biol Chem , vol.285 , pp. 11740-11752
    • Cui, M.1    Tang, X.2    Christian, W.V.3    Yoon, Y.4    Tieu, K.5
  • 68
    • 33646136884 scopus 로고    scopus 로고
    • Mutant huntingtin aggregates impair mitochondrial movement and trafficking in cortical neurons
    • D.T. Chang, G.L. Rintoul, S. Pandipati, and I.J. Reynolds Mutant huntingtin aggregates impair mitochondrial movement and trafficking in cortical neurons Neurobiol Dis 22 2006 388 400
    • (2006) Neurobiol Dis , vol.22 , pp. 388-400
    • Chang, D.T.1    Rintoul, G.L.2    Pandipati, S.3    Reynolds, I.J.4
  • 70
    • 0029881688 scopus 로고    scopus 로고
    • Cognitive impairment in elderly schizophrenia: A dementia (still) lacking distinctive histopathology
    • S.E. Arnold, and J.Q. Trojanowski Cognitive impairment in elderly schizophrenia: A dementia (still) lacking distinctive histopathology Schizophr Bull 22 1996 5 9 (Pubitemid 26081406)
    • (1996) Schizophrenia Bulletin , vol.22 , Issue.1 , pp. 5-9
    • Arnold, S.E.1    Trojanowski, J.Q.2
  • 72
    • 33749991592 scopus 로고    scopus 로고
    • Mitochondrial Inner-Membrane Fusion and Crista Maintenance Requires the Dynamin-Related GTPase Mgm1
    • DOI 10.1016/j.cell.2006.09.021, PII S0092867406012141
    • S. Meeusen, R. DeVay, J. Block, A. Cassidy-Stone, S. Wayson, J.M. McCaffery, and J. Nunnari Mitochondrial inner-membrane fusion and crista maintenance requires the dynamin-related GTPase Mgm1 Cell 127 2006 383 395 (Pubitemid 44572371)
    • (2006) Cell , vol.127 , Issue.2 , pp. 383-395
    • Meeusen, S.1    DeVay, R.2    Block, J.3    Cassidy-Stone, A.4    Wayson, S.5    McCaffery, J.M.6    Nunnari, J.7
  • 73
    • 68149103297 scopus 로고    scopus 로고
    • Mitofusins and OPA1 mediate sequential steps in mitochondrial membrane fusion
    • Z. Song, M. Ghochani, J.M. McCaffery, T.G. Frey, and D.C. Chan Mitofusins and OPA1 mediate sequential steps in mitochondrial membrane fusion Mol Biol Cell 20 2009 3525 3532
    • (2009) Mol Biol Cell , vol.20 , pp. 3525-3532
    • Song, Z.1    Ghochani, M.2    McCaffery, J.M.3    Frey, T.G.4    Chan, D.C.5
  • 74
    • 6344274848 scopus 로고    scopus 로고
    • Roles of the mammalian mitochondrial fission and fusion mediators Fis1, Drp1, Opa1 in apoptosis
    • DOI 10.1091/mbc.E04-04-0294
    • Y.J. Lee, S.Y. Jeong, M. Karbowski, C.L. Smith, and R.J. Youle Roles of the mammalian mitochondrial fission and fusion mediators Fis1, Drp1, and Opa1 in apoptosis Mol Biol Cell 15 2004 5001 5011 (Pubitemid 39392214)
    • (2004) Molecular Biology of the Cell , vol.15 , Issue.11 , pp. 5001-5011
    • Lee, Y.-J.1    Jeong, S.-Y.2    Karbowski, M.3    Smith, C.L.4    Youle, R.J.5
  • 75
    • 0043092647 scopus 로고    scopus 로고
    • The mitochondrial protein hFis1 regulates mitochondrial fission in mammalian cells through an interaction with the dynamin-like protein DLP1
    • DOI 10.1128/MCB.23.15.5409-5420.2003
    • Y. Yoon, E.W. Krueger, B.J. Oswald, and M.A. McNiven The mitochondrial protein hFis1 regulates mitochondrial fission in mammalian cells through an interaction with the dynamin-like protein DLP1 Mol Cell Biol 23 2003 5409 5420 (Pubitemid 36950895)
    • (2003) Molecular and Cellular Biology , vol.23 , Issue.15 , pp. 5409-5420
    • Yoon, Y.1    Krueger, E.W.2    Oswald, B.J.3    McNiven, M.A.4
  • 76
    • 67650868959 scopus 로고    scopus 로고
    • Mitochondrial dynamics in mammalian health and disease
    • M. Liesa, M. Palacin, and A. Zorzano Mitochondrial dynamics in mammalian health and disease Physiol Rev 89 2009 799 845
    • (2009) Physiol Rev , vol.89 , pp. 799-845
    • Liesa, M.1    Palacin, M.2    Zorzano, A.3
  • 77
    • 77957256414 scopus 로고    scopus 로고
    • Abnormalities in mitochondrial structure in cells from patients with bipolar disorder
    • A.M. Cataldo, D.L. McPhie, N.T. Lange, S. Punzell, S. Elmiligy, and N.Z. Ye Abnormalities in mitochondrial structure in cells from patients with bipolar disorder Am J Pathol 177 2010 575 585
    • (2010) Am J Pathol , vol.177 , pp. 575-585
    • Cataldo, A.M.1    McPhie, D.L.2    Lange, N.T.3    Punzell, S.4    Elmiligy, S.5    Ye, N.Z.6
  • 78
    • 12744278205 scopus 로고    scopus 로고
    • Altered expression of mitochondria-related genes in postmortem brains of patients with bipolar disorder or schizophrenia, as revealed by large-scale DNA microarray analysis
    • K. Iwamoto, M. Bundo, and T. Kato Altered expression of mitochondria-related genes in postmortem brains of patients with bipolar disorder or schizophrenia, as revealed by large-scale DNA microarray analysis Hum Mol Genet 14 2005 241 253
    • (2005) Hum Mol Genet , vol.14 , pp. 241-253
    • Iwamoto, K.1    Bundo, M.2    Kato, T.3
  • 79
    • 1642352614 scopus 로고    scopus 로고
    • Mitochondrial complex I subunits expression is altered in schizophrenia: A postmortem study
    • DOI 10.1016/j.biopsych.2003.12.012, PII S0006322304000083
    • R. Karry, E. Klein, and D. Ben Shachar Mitochondrial complex i subunits expression is altered in schizophrenia: A postmortem study Biol Psychiatry 55 2004 676 684 (Pubitemid 38376178)
    • (2004) Biological Psychiatry , vol.55 , Issue.7 , pp. 676-684
    • Karry, R.1    Klein, E.2    Shachar, D.B.3
  • 82
    • 41049092301 scopus 로고    scopus 로고
    • Sp1 expression is disrupted in schizophrenia; a possible mechanism for the abnormal expression of mitochondrial complex I genes, NDUFV1 and NDUFV2
    • D. Ben-Shachar, and R. Karry Sp1 expression is disrupted in schizophrenia; a possible mechanism for the abnormal expression of mitochondrial complex I genes, NDUFV1 and NDUFV2 PLoS ONE 2 2007 e817
    • (2007) PLoS ONE , vol.2 , pp. 817
    • Ben-Shachar, D.1    Karry, R.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.