Cytoprotection by lithium and valproate varies between cell types and cellular stresses

European Journal of Pharmacology

Volumn 539, Issue 1-2, 2006, Pages 18-26

  Lai, Justin S ^a,b   Zhao, Chunnian ^a   Warsh, Jerry J ^a,b,c   Li, Peter P ^a,b,c  

^a CENTRE FOR ADDICTION AND MENTAL HEALTH   (Canada)

^b UNIVERSITY OF TORONTO   (Canada)

^c UNIVERSITY OF TORONTO   (Canada)

Author keywords

Bcl 2; Bipolar disorder; Caspase 3; Cytochrome c; Cytotoxicity; Lithium; Valproate

Indexed keywords

2 (2,4 DICHLOROPHENYL) 3 (1 METHYL 3 INDOLYL)MALEIMIDE; CASPASE 3; CYTOCHROME C; GLYCOGEN SYNTHASE KINASE 3; GLYCOGEN SYNTHASE KINASE 3 INHIBITOR; HYDROGEN PEROXIDE; KENPAULLONE; LITHIUM CHLORIDE; PROTEIN BCL 2; ROTENONE; THAPSIGARGIN; VALPROIC ACID;

ACUTE DRUG ADMINISTRATION; ARTICLE; BIPOLAR DISORDER; CANCER CELL CULTURE; CELL DAMAGE; CELL DEATH; CELL PROTECTION; CELL TYPE; CHRONIC DRUG ADMINISTRATION; CONTROLLED STUDY; CYTOTOXICITY; DISORDERS OF MITOCHONDRIAL FUNCTIONS; DOSE TIME EFFECT RELATION; ENDOPLASMIC RETICULUM; ENZYME ACTIVATION; ENZYME RELEASE; GLIOMA; HUMAN; HUMAN CELL; MACROGLIA; NEUROBLASTOMA; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN EXPRESSION; STRESS; TREATMENT DURATION;

ANTIMANIC AGENTS; CASPASE 3; CASPASES; CELL DEATH; CELL LINE, TUMOR; CYTOCHROMES C; CYTOPROTECTION; ELECTRON TRANSPORT COMPLEX I; ENDOPLASMIC RETICULUM; ENZYME ACTIVATION; ENZYME INHIBITORS; GLIOMA; GLYCOGEN SYNTHASE KINASE 3; HUMANS; HYDROGEN PEROXIDE; LITHIUM COMPOUNDS; NEUROBLASTOMA; NEUROPROTECTIVE AGENTS; OXIDATIVE STRESS; PROTO-ONCOGENE PROTEINS C-BCL-2; ROTENONE; THAPSIGARGIN; UP-REGULATION; VALPROIC ACID;

EID: 33646863671     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejphar.2006.03.076     Document Type: Article

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