PUFA and aging modulate cardiac mitochondrial membrane lipid composition and Ca2+ activation of PDH

American Journal of Physiology - Heart and Circulatory Physiology

Volumn 276, Issue 1 45-1, 1999, Pages

  Pepe, Salvatore ^a,b   Tsuchiya, Naotaka ^a,c   Lakatta, Edward G ^a   Hansford, Richard G ^a,d  

^a NATIONAL INSTITUTE ON AGING   (United States)

^b BAKER IDI HEART AND DIABETES INSTITUTE   (Australia)

^c KITASATO UNIVERSITY HOSPITAL   (Japan)

^d NATIONAL INSTITUTES OF HEALTH   (United States)

Author keywords

Calcium; Heart; Mitochondria; Pyruvate dehydrogenase; Rat; 3 6 polyunsaturated fatty acids

Indexed keywords

CALCIUM ION; OMEGA 3 FATTY ACID; OMEGA 6 FATTY ACID; POLYUNSATURATED FATTY ACID; PYRUVATE DEHYDROGENASE;

AGING; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CALCIUM HOMEOSTASIS; CELL MEMBRANE TRANSPORT; CONTROLLED STUDY; ENZYME ACTIVATION; FAT INTAKE; HEART MITOCHONDRION; LIPID COMPOSITION; LIPID MEMBRANE; MALE; MITOCHONDRIAL MEMBRANE; NONHUMAN; PRIORITY JOURNAL; RAT;

EID: 0032922822     PISSN: 03636135     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajpheart.1999.276.1.h149     Document Type: Article

References (58)

1. 2 production. Am. J. Physiol. 260 (Heart Circ. Physiol. 29): H379-H385, 1991.
2. Akerman, K. E. O., and D. G. Nicholls. Physiological and bioenergetic aspects of mitochondrial calcium transport. Rev. Physiol. Biochem. Pharmacol. 95: 149-201, 1983.
3. Bernardi, P., K. M. Broekemeier, and D. R. Pfeiffer. Recent progress on regulation of the mitochondrial permeability pore; a cyclosporin-sensitive pore in the inner mitochondrial membrane. J. Bioenerg. Biomembr. 26: 509-517, 1994.
4. 31P nuclear magnetic resonance. Biochemistry 24: 3821-3826, 1985.
5. Bligh, E. C., and W. J. Dyer. A rapid method of total lipid extraction and purification. Can. J. Biochem. Physiol. 37: 911-917, 1959.
6. 2+ increases the mitochondrial NADH concentration during elevated work in intact cardiac muscle. Circ. Res. 80: 82-97, 1997.
7. Colbeau, A., J. Machbaur, and P. M. Vignais. Enzymatic characterization and lipid composition of rat liver subcellular membranes. Biochim. Biophys. Acta 249: 462-492, 1971.
8. + channels. J. Biol. Chem. 268: 27335-27344, 1993.
9. Demaison, L., J. P. Sergiel, J. Moreau, and A. Grynberg. Influence of the phospholipid n-3/n-6 PUFA ratio on mitochondrial oxidative metabolism before and after myocardial ischemia. Biochim. Biophys. Acta 1227: 53-59, 1994.
10. Gunter, T. E., and D. R. Pfeiffer. Mechanisms by which mitochondria transport calcium. Am. J. Physiol. 258 (Cell Physiol. 27): C755-C786, 1990.
11. Gupta, M. P., I. M. C. Dixon, D. Zhao, and N. S. Dhalla. Influence of ruthenium red on rat heart subcellular calcium transport. Can. J. Cardiol. 5: 55-63, 1989.
12. Hackenbrock, C. R., B. Chazotte, and S. S. Gupte. The random collision model and a critical assessment of diffusion and collision in mitochondrial electron transport. J. Bioenerg. Biomembr. 18: 331-368, 1986.
13. Hansford, R. G. Bioenergetics in aging. Biochim. Biophys. Acta 726: 41-80, 1983.
14. Hansford, R. G. Dehydrogenase activation by calcium in cells and tissues. J. Bioenerg. Biomembr. 23: 823-854, 1991.
15. Hansford, R. G. Lipid oxidation by heart mitochondria from young adult and senescent rats. Biochem. J. 170: 285-295, 1978.
16. 2+ transport. J. Bioenerg. Biomembr. 26: 495-508, 1994.
17. 2+ concentration and the control of pyruvate dehydrogenase in isolated cardiac myocytes. Biochem. J. 241: 145-151, 1987.
18. Hansford, R. G. Relation between mitochondrial calcium transport and control of energy metabolism. Rev. Physiol. Biochem. Pharmacol. 102: 1-72, 1985.
19. 2+ transport by heart mitochondria. Mech. Ageing Dev. 19: 5-13, 1982.
20. Hansford, R. G., and R. Cohen. Relative importance of pyruvate dehydrogenase interconversion and feed-back inhibition in the effect of fatty acids on pyruvate oxidation by rat heart mitochondria. Arch. Biochem. Biophys. 191: 65-81, 1978.
21. + perfusion of guinea-pig heart. Biochim. Biophys. Acta 1018: 282-286, 1990.
22. Heineman, F. W., and R. S. Balaban. Control of mitochondrial respiration in the heart in vivo. Annu. Rev. Physiol. 52: 523-542, 1990.
23. Hock, C. E., M. A. Holahan, and D. K. Reibel. Effect of dietary fish oil on myocardial phospholipids and myocardial ischemic damage. Am. J. Physiol. 252 (Heart Circ. Physiol. 21): H544-H560, 1987.
24. + channel (Kv1.5) by polyunsaturated fatty acids. Proc. Natl. Acad. Sci. USA 91: 1937-1941, 1994.
25. Innis, S. M., and M. T. Clandinin. Dynamic modulation of mitochondrial inner membrane lipids in rat heart by dietary fat. Biochem. J. 193: 155-167, 1981.
26. Innis, S. M., and M. T. Clandinin. Dynamic modulation of mitochondrial membrane physical properties and ATPase activity by dietary lipid. Biochem. J. 198: 168-175, 1981.
27. Isenberg, G., S. Han, A. Schiefer, and M. F. Wendt-Gallitelli. Changes in mitochondrial calcium concentration during the cardiac contraction cycle. Cardiovasc. Res. 27: 1800-1809, 1993.
28. Kobayashi, K., and J. R. Neely. Effects of ischemia and reperfusion on pyruvate dehydrogenase activity in isolated rat hearts. J. Mol. Cell. Cardiol. 15: 359-367, 1983.
29. 2+. Biochem. J. 218: 235-247, 1984.
30. McCormack, J. G., and P. J. England. Ruthenium red inhibits the activation of pyruvate dehydrogenase caused by positive inotropic agents in the perfused rat heart. Biochem. J. 214: 581-583, 1983.
31. McCormack, J. G., A. P. Halestrap, and R. M. Denton. Role of calcium ions in the regulation of mammalian intramitochondrial metabolism. Physiol. Rev. 70: 391-425, 1990.
32. McLennan, P. L., M. Y. Abeywardena, and J. S. Charnock. The influence of age and dietary fat in an animal model of sudden cardiac death. Aust. NZ J. Med. 19: 1-5, 1989.
33. McLennan, P. L., T. M. Bridle, M. Y. Abeywardena, and J. S. Charnock. Comparative efficacy of n-3 and n-6 polyunsaturated fatty acids in modulating ventricular fibrillation threshold in marmoset monkeys. Am. J. Clin. Nutr. 58: 666-669, 1993.
34. McMillin, J. B., R. J. Bick, and C. R. Benedict. The influence of dietary fish oil on mitochondrial function and response to ischemia. Am. J. Physiol. 263 (Heart Circ: Physiol. 32): H1479-H1485, 1992.
35. 2+ concentration in living single rat cardiac myocytes. Am. J. Physiol. 261 (Heart Circ. Physiol. 30): H1123-H1134, 1991.
36. 2+ concentration. Biochem. J. 256: 403-412, 1988.
37. Moreno-Sanchez, R., B. A. Hogue, and R. G. Hansford. Influence of NAD-linked dehydrogenase activity on flux through oxidative phosphorylation. Biochem. J. 268: 421-428, 1990.
38. Nicholls, D. G. The influence of respiration and ATP hydrolysis on the proton-electrochemical gradient across the inner membrane of rat liver mitochondria as determined by ion distribution. Eur. J. Biochem. 50: 305-315, 1974.
39. Nohl, H. Influence of age on thermotropic kinetics of enzymes involved in mitochondrial energy metabolism. Z. Gerontol. 12: 9-18, 1979.
40. Nohl, H. Age-dependent changes in the structure-function correlation of ADP/ATP-translocating mitochondrial membranes. Gerontology 28: 354-359, 1982.
41. Noel, H., and S. V. Pande. An essential requirement of cardiolipin for mitochondrial carnitine acylcarnitine translocase activity. Lipid requirement of carnitine acylcarnitine translocase. Eur. J. Biochem. 155: 99-102, 1986.
42. Oudot, F., A. Grynberg, and J. P. Sergiel. Eicosanoid synthesis in cardiomyocytes: influence of hypoxia, reoxygenation, and polyunsaturated fatty acids. Am. J. Physiol. 268 (Heart Circ. Physiol. 37): H308-H315, 1995.
43. Paradies, G., F. M. Ruggiero, M. N. Gadaleta, and E. Quagliariello. The effect of aging and acetyl-L-carnitine on the activity of the phosphate carrier and on the phospholipid composition in rat heart mitochondria. Biochim. Biophys. Acta 1103: 324-326, 1992.
44. 2+, and contraction in adult rat cardiac myocytes. Proc. Natl. Acad. Sci. USA 91: 8832-8836, 1994.
45. Pepe, S., and P. L. McLennan. Modulation of myocardial oxygen requirements by dietary lipids in the isolated erythrocyte perfused working rat heart. J. Mol. Cell. Cardiol. 24, Suppl. I: S115, 1992.
46. Pepe, S., and P. L. McLennan. Increased ventricular fibrillation threshold and reduced incidence of cardiac arrhythmias after polyunsaturated fish oil dietary supplementation. J. Nutr. 126: 34-42, 1996.
47. 2+ permeability of cardiac sarcolemmal vesicles. J. Biol. Chem. 260: 9666-9671, 1985.
48. Richter, C., M. Schweizer, A. Cossarizza, and C. Franceschi. Control of apoptosis by the cellular ATP level. FEBS Lett. 378: 107-110, 1996.
49. Suzuki, Y. J., H. J. Forman, and A. Sevanian. Oxidants as stimulators of signal transduction. Free Radic. Biol. Med. 22: 269-285, 1997.
50. Taffet, G. E., T. T. Pham, D. L. Bick, M. L. Entman, H. J. Pownall, and R. J. Bick. The calcium uptake of the rat heart sarcoplasmic reticulum is altered by dietary lipid. J. Membr. Biol. 131: 35-42, 1993.
51. 31P NMR and ruthenium red. Biochem. J. 262: 293-301, 1989.
52. K.PC. J. Gen. Physiol. 98: 921-939, 1991.
53. Wieland, O. H. The mammalian pyruvate dehydrogenase complex: structure and regulation. Rev. Physiol. Biochem. Pharmacol. 96: 123-170, 1983.
54. + channels of neonatal rat ventricular myocytes. Proc. Natl. Acad. Sci. USA 92: 11000-11004, 1995.
55. Yamaoka, S., R. Urade, and M. Kito. Cardiolipin molecular species in rat heart mitochondria are sensitive to essential fatty acid-deficient lipids. J. Nutr. 120: 415-421, 1990.
56. Yamaoka, S., R. Urade, and M. Kito. Mitochondrial function in rats is affected by modification of membrane phospholipids with dietary sardine oil. J. Nutr. 120: 415-421, 1988.
57. Yang, B., T. G. P. Saldeen, J. L. Bryant, W. W. Nichols, and J. L. Mebta. Long-term dietary fish oil supplementation protects against ischaemia-reperfusion induced myocardial dysfunction in isolated rat hearts. Am. Heart J. 126: 1287-1292, 1993.
58. Yang, B., T. G. P. Saldeen, W. W. Nichols, and J. L. Mehta. Dietary fish oil supplementation attenuates myocardial dysfunction and injury caused by global ischaemia and reperfusion in isolated rat hearts. J. Nutr. 123: 2067-2074, 1993.