TNF-α and IL-1α inhibit both pyruvate dehydrogenase activity and mitochondrial function in cardiomyocytes: Evidence for primary impairment of mitochondrial function

Molecular and Cellular Biochemistry

Volumn 177, Issue 1-2, 1997, Pages 61-67

  Zell, Robert ^a   Geck, Peter ^b   Werdan, Karl ^c   Boekstegers, Peter ^a  

^a LUDWIG MAXIMILIANS UNIVERSITY   (Germany)

^b GOETHE UNIVERSITY   (Germany)

^c MARTIN LUTHER UNIVERSITY HALLE WITTENBERG   (Germany)

Author keywords

Cardiomyocytes; IL1 ; Mitochondrial function; PDH; TNF

Indexed keywords

DICHLOROACETIC ACID; INTERLEUKIN 1ALPHA; PYRUVATE DEHYDROGENASE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE DEHYDROGENASE (UBIQUINONE); SUCCINATE DEHYDROGENASE (UBIQUINONE); TUMOR NECROSIS FACTOR ALPHA;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; ENZYME INHIBITION; HEART MUSCLE CELL; HEART MUSCLE METABOLISM; MITOCHONDRIAL RESPIRATION; NEWBORN; NONHUMAN; OXYGEN CONSUMPTION; RAT; RESPIRATORY CHAIN;

ANIMALIA;

EID: 0030730082     PISSN: 03008177     EISSN: None     Source Type: Journal    
DOI: 10.1023/a:1006896832582     Document Type: Article

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