-
1
-
-
0015363173
-
The cellular production of hydrogen peroxide
-
Boveris, A., Oshino, N., and Chance, B. (1972) The cellular production of hydrogen peroxide. Biochem. J. 128, 617-630.
-
(1972)
Biochem. J.
, vol.128
, pp. 617-630
-
-
Boveris, A.1
Oshino, N.2
Chance, B.3
-
2
-
-
13044285432
-
Mitochondrial disease in superoxide dismutase 2 mutant mice
-
Melov, S., Coskun, P., Patel, M., Tuinstra, M., Cottrell, B., Jun, A. S., Zastawny, T. H., Dizdaroglu, M., Goodman, S. I., Huang, T. T., Miziorko, H., Epstein, C. J., and Wallace, D. C. (1999) Mitochondrial disease in superoxide dismutase 2 mutant mice. Proc. Natl. Acad. Sci. USA 96, 846-851.
-
(1999)
Proc. Natl. Acad. Sci. USA
, vol.96
, pp. 846-851
-
-
Melov, S.1
Coskun, P.2
Patel, M.3
Tuinstra, M.4
Cottrell, B.5
Jun, A.S.6
Zastawny, T.H.7
Dizdaroglu, M.8
Goodman, S.I.9
Huang, T.T.10
Miziorko, H.11
Epstein, C.J.12
Wallace, D.C.13
-
3
-
-
0034062554
-
Mitochondrial oxidative stress in mice lacking the glutathione peroxidase-1 gene
-
Esposito, L. A., Kokoszka, J. E., Waymire, K. G., Cottrell, B., MacGregor, G. R., and Wallace, D. C. (2000) Mitochondrial oxidative stress in mice lacking the glutathione peroxidase-1 gene. Free Radic. Biol. Med. 28, 754-766.
-
(2000)
Free Radic. Biol. Med.
, vol.28
, pp. 754-766
-
-
Esposito, L.A.1
Kokoszka, J.E.2
Waymire, K.G.3
Cottrell, B.4
MacGregor, G.R.5
Wallace, D.C.6
-
4
-
-
0028931989
-
Hydroxyl radical generation during mitochondrial electron transfer and the formation of 8-hydroxydesoxyguanosine in mitochondrial DNA
-
Giulivi, C., Boveris, A., and Cadenas, E. (1995) Hydroxyl radical generation during mitochondrial electron transfer and the formation of 8-hydroxydesoxyguanosine in mitochondrial DNA. Arch. Biochem. Biophys. 316, 909-916.
-
(1995)
Arch. Biochem. Biophys.
, vol.316
, pp. 909-916
-
-
Giulivi, C.1
Boveris, A.2
Cadenas, E.3
-
5
-
-
0035863011
-
Mitochondrial respiratory chain-dependent generation of superoxide anion and its release into the intermembrane space
-
Han, D., Williams, E., and Cadenas, E. (2001) Mitochondrial respiratory chain-dependent generation of superoxide anion and its release into the intermembrane space. Biochem. J. 353, 411-416.
-
(2001)
Biochem. J.
, vol.353
, pp. 411-416
-
-
Han, D.1
Williams, E.2
Cadenas, E.3
-
6
-
-
0019083215
-
Generation of superoxide anion by the NADH dehydrogenase of bovine heart mitochondria
-
Turrens, J. F., and Boveris, A. (1980) Generation of superoxide anion by the NADH dehydrogenase of bovine heart mitochondria. Biochem. J. 191, 421-427.
-
(1980)
Biochem. J.
, vol.191
, pp. 421-427
-
-
Turrens, J.F.1
Boveris, A.2
-
7
-
-
0031853099
-
Substrate and site specificity of hydrogen peroxide generation in mouse mitochondria
-
Kwong, L. K., and Sohal, R. S. (1998) Substrate and site specificity of hydrogen peroxide generation in mouse mitochondria. Arch. Biochem. Biophys. 350, 118-126.
-
(1998)
Arch. Biochem. Biophys.
, vol.350
, pp. 118-126
-
-
Kwong, L.K.1
Sohal, R.S.2
-
8
-
-
0015694375
-
2 formation: Relationship with energy conservation
-
2 formation: relationship with energy conservation. FEBS Lett. 33, 84-87.
-
(1973)
FEBS Lett.
, vol.33
, pp. 84-87
-
-
Loschen, G.1
Azzi, A.2
Flohe, L.3
-
10
-
-
0020586897
-
Effect of electron transfer inhibitors on superoxide generation in the cytochrome bc1 site of the mitochondrial respiratory chain
-
Ksenzenko, M., Konstantinov, A. A., Khomutov, G. B., Tikhonov, A. N., and Ruuge, E. K. (1983) Effect of electron transfer inhibitors on superoxide generation in the cytochrome bc1 site of the mitochondrial respiratory chain. FEBS Lett. 155, 19-24.
-
(1983)
FEBS Lett.
, vol.155
, pp. 19-24
-
-
Ksenzenko, M.1
Konstantinov, A.A.2
Khomutov, G.B.3
Tikhonov, A.N.4
Ruuge, E.K.5
-
11
-
-
0032504657
-
Role of mitochondria in oxidative stress and aging
-
Lenaz, G. (1998) Role of mitochondria in oxidative stress and aging. Biochim. Biophys. Acta 1366, 53-67.
-
(1998)
Biochim. Biophys. Acta
, vol.1366
, pp. 53-67
-
-
Lenaz, G.1
-
12
-
-
0030068461
-
Conditions allowing redox-cycling ubisemiquinone in mitochondria to establish a direct redox couple with molecular oxygen
-
Nohl, H., Gille, L., Schönheit, K., and Liu, Y. (1996) Conditions allowing redox-cycling ubisemiquinone in mitochondria to establish a direct redox couple with molecular oxygen. Free Radic. Biol. Med. 20, 207-213.
-
(1996)
Free Radic. Biol. Med.
, vol.20
, pp. 207-213
-
-
Nohl, H.1
Gille, L.2
Schönheit, K.3
Liu, Y.4
-
13
-
-
0032189721
-
Antioxidant-derived prooxidant formation from ubiquinol
-
Nohl, H., Gille, L., and Kozlov, A.V. (1998) Antioxidant-derived prooxidant formation from ubiquinol. Free Radic. Biol. Med. 25, 666-675.
-
(1998)
Free Radic. Biol. Med.
, vol.25
, pp. 666-675
-
-
Nohl, H.1
Gille, L.2
Kozlov, A.V.3
-
14
-
-
0034661024
-
Superoxides from mitochondrial Complex III: The role of manganese superoxide dismutase
-
Raha, S., McEachern, G. E., Myint, A. T., and Robinson, B. H. (2000) Superoxides from mitochondrial Complex III: the role of manganese superoxide dismutase. Free Radic. Biol. Med. 29, 170-180.
-
(2000)
Free Radic. Biol. Med.
, vol.29
, pp. 170-180
-
-
Raha, S.1
McEachern, G.E.2
Myint, A.T.3
Robinson, B.H.4
-
15
-
-
0035929367
-
The site of production of superoxide radical in mitochondrial Complex I is not a bound ubisemquinone but presumably iron-sulfur cluster N2
-
Genova, M. L., Ventura, B., Giuliano, G., Bovina, C., Formiggini, G., Parenti Castelli, G., and Lenaz G. (2001) The site of production of superoxide radical in mitochondrial Complex I is not a bound ubisemquinone but presumably iron-sulfur cluster N2. FEBS Lett.
-
(2001)
FEBS Lett.
-
-
Genova, M.L.1
Ventura, B.2
Giuliano, G.3
Bovina, C.4
Formiggini, G.5
Parenti Castelli, G.6
Lenaz, G.7
-
16
-
-
0018393931
-
NADH and NADPH-dependent formation of superoxide anions by bovine heart submitochondrial particles and NADH-ubiquinone reductase preparation
-
Takeshige, K., and Minakami, S. (1979) NADH and NADPH-dependent formation of superoxide anions by bovine heart submitochondrial particles and NADH-ubiquinone reductase preparation. Biochem. J. 180, 129-135.
-
(1979)
Biochem. J.
, vol.180
, pp. 129-135
-
-
Takeshige, K.1
Minakami, S.2
-
17
-
-
0017406503
-
Production of superoxide radicals and hydrogen peroxide by NADH-ubiquinone reductase and ubiquinol-cytochrome c reductase from beef heart mitochondria
-
Cadenas, E., Boveris, A., Ragan, C. I., and Stoppani, A. O. M. (1977) Production of superoxide radicals and hydrogen peroxide by NADH-ubiquinone reductase and ubiquinol-cytochrome c reductase from beef heart mitochondria. Arch. Biochem. Biophys. 180, 248-257.
-
(1977)
Arch. Biochem. Biophys.
, vol.180
, pp. 248-257
-
-
Cadenas, E.1
Boveris, A.2
Ragan, C.I.3
Stoppani, A.O.M.4
-
18
-
-
0022967083
-
Redox cycling of anthracyclines by cardiac mitochondria. I. Anthracycline radical formation by NADH dehydrogenase
-
Davies, K. J., and Doroshow, J. H. (1986) Redox cycling of anthracyclines by cardiac mitochondria. I. Anthracycline radical formation by NADH dehydrogenase. J. Biol. Chem. 261, 3060-3067.
-
(1986)
J. Biol. Chem.
, vol.261
, pp. 3060-3067
-
-
Davies, K.J.1
Doroshow, J.H.2
-
19
-
-
0000701926
-
The interaction of Q analogs, particularly hydroxydecyl benzoquinone (idebenone), with the respiratory complexes of heart mitochondria
-
Degli Esposti, M., Ngo, A., Ghelli, A., Benelli, B., Carelli, V., McLennan, H., and Lirnnane, A. W. (1996) The interaction of Q analogs, particularly hydroxydecyl benzoquinone (idebenone), with the respiratory complexes of heart mitochondria. Arch. Biochem. Biophys. 330, 395-400.
-
(1996)
Arch. Biochem. Biophys.
, vol.330
, pp. 395-400
-
-
Degli Esposti, M.1
Ngo, A.2
Ghelli, A.3
Benelli, B.4
Carelli, V.5
McLennan, H.6
Lirnnane, A.W.7
-
20
-
-
0033369476
-
Mitochondrial oxygen radical generation and leak: Sites of production in states 4 and 3, organ specificity, and relation to aging and longevity
-
Barja, G. (1999) Mitochondrial oxygen radical generation and leak: sites of production in states 4 and 3, organ specificity, and relation to aging and longevity. J. Bioenerg. Biomembr. 31, 347-366.
-
(1999)
J. Bioenerg. Biomembr.
, vol.31
, pp. 347-366
-
-
Barja, G.1
-
21
-
-
0034467677
-
Localization of the site of oxygen radical generation inside the Complex I of heart and nonsynaptic brain mammalian mitochondria
-
Herrero, A., and Barja, G. (2000) Localization of the site of oxygen radical generation inside the Complex I of heart and nonsynaptic brain mammalian mitochondria. J. Bioenerg. Biomembr. 32, 609-616.
-
(2000)
J. Bioenerg. Biomembr.
, vol.32
, pp. 609-616
-
-
Herrero, A.1
Barja, G.2
-
22
-
-
0033858360
-
The contribution of mitochondrial respiratory complexes to the production of reactive oxygen species
-
McLennan, H. R., and Degli Esposti, M. (2000) The contribution of mitochondrial respiratory complexes to the production of reactive oxygen species. J. Bioenerg. Biomembr. 32, 153-162.
-
(2000)
J. Bioenerg. Biomembr.
, vol.32
, pp. 153-162
-
-
McLennan, H.R.1
Degli Esposti, M.2
-
23
-
-
0032490114
-
Inhibitors of NADH-ubiquinone reductase: An overview
-
Degli Esposti, M. (1998) Inhibitors of NADH-ubiquinone reductase: an overview. Biochim. Biophys. Acta 1364, 222-235.
-
(1998)
Biochim. Biophys. Acta
, vol.1364
, pp. 222-235
-
-
Degli Esposti, M.1
-
24
-
-
0032490089
-
Iron-sulfur clusters/semiquinones in Complex I
-
Ohnishi, T. (1998) Iron-sulfur clusters/semiquinones in Complex I. Biochim. Biophys. Acta 1364, 186-206.
-
(1998)
Biochim. Biophys. Acta
, vol.1364
, pp. 186-206
-
-
Ohnishi, T.1
-
25
-
-
0029029471
-
Modelling the effects of age-related mtDNA mutation accumulation: Complex I deficiency, superoxide and cell death
-
Cortopassi, G., and Wang, E. (1995) Modelling the effects of age-related mtDNA mutation accumulation: Complex I deficiency, superoxide and cell death. Biochim. Biophys. Acta 1271, 171-176.
-
(1995)
Biochim. Biophys. Acta
, vol.1271
, pp. 171-176
-
-
Cortopassi, G.1
Wang, E.2
-
26
-
-
0032514466
-
A mutation in succinate dehydrogenas e cytochrome b causes oxidative stress and ageing in nematodes
-
Ishii, N., Fujii, M., Hartman, P. S., Tsuda, M., Yasuda, K., Senoo-Matsuda, N., Yanase, S., Ayusawa, D., and Suzuki, K. (1998) A mutation in succinate dehydrogenas e cytochrome b causes oxidative stress and ageing in nematodes. Nature 394, 694-697.
-
(1998)
Nature
, vol.394
, pp. 694-697
-
-
Ishii, N.1
Fujii, M.2
Hartman, P.S.3
Tsuda, M.4
Yasuda, K.5
Senoo-Matsuda, N.6
Yanase, S.7
Ayusawa, D.8
Suzuki, K.9
-
27
-
-
0032545269
-
Generation of superoxide anion by succinate cytochrome c reductase from bovine heart mitochondria
-
Zhang, L., Yu, L., and Yu, C. A. (1998) Generation of superoxide anion by succinate cytochrome c reductase from bovine heart mitochondria. J. Biol. Chem. 273, 33972-33976.
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 33972-33976
-
-
Zhang, L.1
Yu, L.2
Yu, C.A.3
-
28
-
-
0025319220
-
Extramitochondrial release of hydrogen peroxide from insect and mouse liver mitochondria using the respiratory inhibitors phosphine, myxothiazol, and antimycin and spectral analysis of inhibited cytochromes
-
Bolter, C. J., and Chefurka, W. (1990) Extramitochondrial release of hydrogen peroxide from insect and mouse liver mitochondria using the respiratory inhibitors phosphine, myxothiazol, and antimycin and spectral analysis of inhibited cytochromes. Arch. Biochem. Biophys. 278, 65-72.
-
(1990)
Arch. Biochem. Biophys.
, vol.278
, pp. 65-72
-
-
Bolter, C.J.1
Chefurka, W.2
-
29
-
-
0007705725
-
Specific properties of Coenzyme Q function in brown adipose tissue cells
-
Ebadi, M., Marwah, J., Chopra, R. eds.. chapter 6. Prominent Press, Scottsdale, Arizona
-
Rauchova, H., Drahota, Z., and Lenaz, G. (2001) Specific properties of Coenzyme Q function in brown adipose tissue cells. In Mitochondrial Ubiquinone (Coenzyme Q10) (Ebadi, M., Marwah, J., Chopra, R. eds.). chapter 6. Prominent Press, Scottsdale, Arizona, 217-219.
-
(2001)
Mitochondrial Ubiquinone (Coenzyme Q10)
, pp. 217-219
-
-
Rauchova, H.1
Drahota, Z.2
Lenaz, G.3
-
30
-
-
0016750459
-
Superoxide production and electron transport in mitochondrial oxidation of dihydroorotic acid
-
Forman, J. H., and Kennedy, J. (1975) Superoxide production and electron transport in mitochondrial oxidation of dihydroorotic acid. J. Biol. Chem. 250, 4322-4326.
-
(1975)
J. Biol. Chem.
, vol.250
, pp. 4322-4326
-
-
Forman, J.H.1
Kennedy, J.2
-
31
-
-
0025990299
-
Malarial dihydroorotate dehydrogenase mediates superoxide radical production
-
Krungkrai, J. (1991) Malarial dihydroorotate dehydrogenase mediates superoxide radical production. Biochem. Int. 24, 833-839.
-
(1991)
Biochem. Int.
, vol.24
, pp. 833-839
-
-
Krungkrai, J.1
-
32
-
-
0034693690
-
Are mitochondria a permanent source of reactive oxygen species?
-
Staniek, K., and Nohl, H. (2000) Are mitochondria a permanent source of reactive oxygen species? Biochim. Biophys. Acta 1460, 268-275.
-
(2000)
Biochim. Biophys. Acta
, vol.1460
, pp. 268-275
-
-
Staniek, K.1
Nohl, H.2
-
33
-
-
0030729851
-
High protonic potential actuates a mechanism of production of reactive oxygen species in mitochondria
-
Korshunov, S.S., Skulachev, V. P., and Starkov, A. A. (1997) High protonic potential actuates a mechanism of production of reactive oxygen species in mitochondria. FEBS Lett. 416, 15-18.
-
(1997)
FEBS Lett.
, vol.416
, pp. 15-18
-
-
Korshunov, S.S.1
Skulachev, V.P.2
Starkov, A.A.3
-
34
-
-
0029765443
-
Role of uncoupled and non-coupled oxidations in maintenance of safely low levels of oxygen and its one-electron reductants
-
Skulachev, V. P. (1996) Role of uncoupled and non-coupled oxidations in maintenance of safely low levels of oxygen and its one-electron reductants. Q. Rev. Biophys. 29, 169-202.
-
(1996)
Q. Rev. Biophys.
, vol.29
, pp. 169-202
-
-
Skulachev, V.P.1
-
35
-
-
0033785071
-
Uncoupling to survive? the role of mitochondrial inefficiency in ageing
-
Brand, M. D. (2000) Uncoupling to survive? The role of mitochondrial inefficiency in ageing. Exp. Gerontol. 35, 811-820.
-
(2000)
Exp. Gerontol.
, vol.35
, pp. 811-820
-
-
Brand, M.D.1
-
36
-
-
12644257598
-
Mutations in mitochondrial cytochrome c oxidase genes segregate with late onset Alzheimer disease
-
Davis, R. E., Miller, S.W., Herrnstadt, C., Ghosh, S.S., Fahy, E., Shinobu, L., Galasko, D., Thal, L. J., Beal, M. F., Howell, N., and Parker, W. D., Jr. (1997) Mutations in mitochondrial cytochrome c oxidase genes segregate with late onset Alzheimer disease. Proc. Natl. Acad. Sci. USA 94, 4564-4569.
-
(1997)
Proc. Natl. Acad. Sci. USA
, vol.94
, pp. 4564-4569
-
-
Davis, R.E.1
Miller, S.W.2
Herrnstadt, C.3
Ghosh, S.S.4
Fahy, E.5
Shinobu, L.6
Galasko, D.7
Thal, L.J.8
Beal, M.F.9
Howell, N.10
Parker Jr., W.D.11
-
37
-
-
0343714594
-
Mitochondrial energy metabolism is regulated via nuclear-coded subunits of cytochrome c oxidase
-
Kadenbach, B., Hüttermann, M., Arnold, S., Lee, I., and Bender, E. (2000) Mitochondrial energy metabolism is regulated via nuclear-coded subunits of cytochrome c oxidase. Free Radic. Biol. Med. 29, 211-221.
-
(2000)
Free Radic. Biol. Med.
, vol.29
, pp. 211-221
-
-
Kadenbach, B.1
Hüttermann, M.2
Arnold, S.3
Lee, I.4
Bender, E.5
-
38
-
-
1842330849
-
Direct effect of ceramide on the mitochondrial electron transport chain leads to generation of reactive oxygen species
-
Garcia-Ruiz, C., Colell, A., Marì, M., Morales, A., and Fernandez-Checa, J. C. (1997) Direct effect of ceramide on the mitochondrial electron transport chain leads to generation of reactive oxygen species. J. Biol. Chem. 272, 11369-11377.
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 11369-11377
-
-
Garcia-Ruiz, C.1
Colell, A.2
Marì, M.3
Morales, A.4
Fernandez-Checa, J.C.5
-
39
-
-
0032496143
-
Superoxide in apoptosis. Mitochondrial generation triggered by cytochrome c loss
-
Cai, J., and Jones, D. P. (1998) Superoxide in apoptosis. Mitochondrial generation triggered by cytochrome c loss. J. Biol. Chem. 273, 11401-11404.
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 11401-11404
-
-
Cai, J.1
Jones, D.P.2
-
40
-
-
0344758310
-
Arachidonic acid interaction with the mitochondrial electron transport chain promotes reactive oxygen species generation
-
Cocco, T., Di Paola, M., Papa, S., and Lorusso, M. (1999) Arachidonic acid interaction with the mitochondrial electron transport chain promotes reactive oxygen species generation. Free Radic. Biol. Med. 27, 51-59.
-
(1999)
Free Radic. Biol. Med.
, vol.27
, pp. 51-59
-
-
Cocco, T.1
Di Paola, M.2
Papa, S.3
Lorusso, M.4
-
41
-
-
0035853767
-
Arachidonic acid causes cell death through the mitochondrial permeability transition
-
Scorrano, L., Penzo, D., Petronilli, V., Pagano, F., and Bernardi, P. (2001) Arachidonic acid causes cell death through the mitochondrial permeability transition. J. Biol. Chem. 276, 12035-12040.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 12035-12040
-
-
Scorrano, L.1
Penzo, D.2
Petronilli, V.3
Pagano, F.4
Bernardi, P.5
-
42
-
-
0033522924
-
Titrating the effects of mitochondrial Complex I impairment in the cell physiology
-
Barrientos, A., and Moraes, C. T. (1999) Titrating the effects of mitochondrial Complex I impairment in the cell physiology. J. Biol. Chem. 274, 16188-16197.
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 16188-16197
-
-
Barrientos, A.1
Moraes, C.T.2
-
43
-
-
0030056515
-
Mitochondrial Complex I deficiency leads to increased production of superoxide radicals and induction of superoxide dismutase
-
Pitkänen, S., and Robinson, B. H. (1996) Mitochondrial Complex I deficiency leads to increased production of superoxide radicals and induction of superoxide dismutase. J. Clin. Invest. 98, 345-351.
-
(1996)
J. Clin. Invest.
, vol.98
, pp. 345-351
-
-
Pitkänen, S.1
Robinson, B.H.2
-
44
-
-
0031561413
-
mtDNA mutations confer cellular sensitivity to oxidant stress that is partly rescued by calcium depletion and cyclosporin A
-
Wong, A., and Cortopassi, G. (1997) mtDNA mutations confer cellular sensitivity to oxidant stress that is partly rescued by calcium depletion and cyclosporin A. Biochem. Biophys. Res. Commun. 239, 139-145.
-
(1997)
Biochem. Biophys. Res. Commun.
, vol.239
, pp. 139-145
-
-
Wong, A.1
Cortopassi, G.2
-
45
-
-
0029908226
-
Origin and functional consequence s of the Complex I defect in Parkinson's disease
-
Swerdlow, R. H., Parks, J. K., Miller, S. W., Tuttle, J. B., Trimmer, P. A., Sheehan, J. P., Bennett, J. P. Jr., Davis, R. E., and Parker, W. D., Jr. (1996) Origin and functional consequence s of the Complex I defect in Parkinson's disease. Ann. Neurol. 40, 663-671.
-
(1996)
Ann. Neurol.
, vol.40
, pp. 663-671
-
-
Swerdlow, R.H.1
Parks, J.K.2
Miller, S.W.3
Tuttle, J.B.4
Trimmer, P.A.5
Sheehan, J.P.6
Bennett Jr., J.P.7
Davis, R.E.8
Parker Jr., W.D.9
-
46
-
-
0025346436
-
A rapid bioessay for chemicals that induce pro-oxidant states
-
Knobeloch, L. M., Blondin, G. A., Lyford, S. B., and Harkin, J. M. (1990) A rapid bioessay for chemicals that induce pro-oxidant states. J. Appl. Toxicol. 10, 1-5.
-
(1990)
J. Appl. Toxicol.
, vol.10
, pp. 1-5
-
-
Knobeloch, L.M.1
Blondin, G.A.2
Lyford, S.B.3
Harkin, J.M.4
|