Fenproporex increases locomotor activity and alters energy metabolism, and mood stabilizers reverse these changes: A proposal for a new animal model of mania

Molecular Neurobiology

Volumn 49, Issue 2, 2014, Pages 877-892

  Rezin, Gislaine T ^a,b   Furlanetto, Camila B ^a,b   Scaini, Giselli ^a,b   Valvassori, Samira S ^a,b   Gonçalves, Cinara L ^a,b   Ferreira, Gabriela K ^a,b   Jeremias, Isabela C ^a,b   Resende, Wilson R ^a,b   Cardoso, Mariane R ^a,b   Varela, Roger B ^a,b   Quevedo, João ^a,b   Streck, Emilio L ^a,b  

^a UNIVERSIDADE DO EXTREMO SUL CATARINENSE   (Brazil)

^b Instituto Nacional de Ciencia e Tecnologia Translacional em Medicina INCT TM   (Brazil)

Author keywords

Behavior; Creatine kinase; Fenproporex; Krebs cycle; Mitochondrial respiratory chain

Indexed keywords

CITRATE SYNTHASE; CREATINE KINASE; FENPROPOREX; LITHIUM; MALATE DEHYDROGENASE; SUCCINATE DEHYDROGENASE; SUCCINATE DEHYDROGENASE COMPLEX I; SUCCINATE DEHYDROGENASE COMPLEX II; SUCCINATE DEHYDROGENASE COMPLEX III; SUCCINATE DEHYDROGENASE COMPLEX IV; UNCLASSIFIED DRUG; VALPROIC ACID; AMPHETAMINE DERIVATIVE; TRANQUILIZER;

ADULT; ANIMAL BEHAVIOR; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BEHAVIOR CHANGE; BRAIN METABOLISM; BRAIN MITOCHONDRION; BRAIN REGION; CHRONIC DRUG ADMINISTRATION; CITRIC ACID CYCLE; COMPLEX FORMATION; CONSTRUCT VALIDITY; CONTROLLED STUDY; DISEASE MODEL; ENERGY METABOLISM; FACE VALIDITY; LOCOMOTION; MALE; MANIA; MITOCHONDRIAL RESPIRATION; NONHUMAN; PREDICTIVE VALIDITY; RAT; RESPIRATORY CHAIN; STEREOTYPY; ANIMAL; BIPOLAR DISORDER; DOSE RESPONSE; DRUG EFFECTS; METABOLISM; MOTOR ACTIVITY; PHYSIOLOGY; WISTAR RAT;

AMPHETAMINES; ANIMALS; ANTIMANIC AGENTS; BIPOLAR DISORDER; DISEASE MODELS, ANIMAL; DOSE-RESPONSE RELATIONSHIP, DRUG; ENERGY METABOLISM; LITHIUM; MALE; MOTOR ACTIVITY; RATS; RATS, WISTAR; VALPROIC ACID;

EID: 84896503674     PISSN: 08937648     EISSN: 15591182     Source Type: Journal    
DOI: 10.1007/s12035-013-8566-8     Document Type: Article

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