-
3
-
-
84892763878
-
Reversing DNA methylation: Mechanisms, genomics, and biological functions
-
Wu, H. & Zhang, Y. Reversing DNA methylation: mechanisms, genomics, and biological functions. Cell 156, 45-68 (2014).
-
(2014)
Cell
, vol.156
, pp. 45-68
-
-
Wu, H.1
Zhang, Y.2
-
4
-
-
84898814417
-
Gene expression regulation mediated through reversible m6A RNA methylation
-
Fu, Y., Dominissini, D., Rechavi, G. & He, C. Gene expression regulation mediated through reversible m6A RNA methylation. Nat. Rev. Genet. 15, 293-306 (2014).
-
(2014)
Nat. Rev. Genet.
, vol.15
, pp. 293-306
-
-
Fu, Y.1
Dominissini, D.2
Rechavi, G.3
He, C.4
-
5
-
-
0034712047
-
Mammalian neural stem cells
-
Gage, F. H. Mammalian neural stem cells. Science 287, 1433-1438 (2000).
-
(2000)
Science
, vol.287
, pp. 1433-1438
-
-
Gage, F.H.1
-
6
-
-
84950138219
-
Adult mammalian neural stem cells and neurogenesis: Five decades later
-
Bond, A. M., Ming, G.-L. & Song, H. Adult mammalian neural stem cells and neurogenesis: five decades later. Cell Stem Cell 17, 385-395 (2015).
-
(2015)
Cell Stem Cell
, vol.17
, pp. 385-395
-
-
Bond, A.M.1
Ming, G.-L.2
Song, H.3
-
7
-
-
79956209852
-
Adult neurogenesis in the mammalian brain: Significant answers and significant questions
-
Ming, G. L. & Song, H. Adult neurogenesis in the mammalian brain: significant answers and significant questions. Neuron 70, 687-702 (2011).
-
(2011)
Neuron
, vol.70
, pp. 687-702
-
-
Ming, G.L.1
Song, H.2
-
8
-
-
84943302841
-
Noncanonical sites of adult neurogenesis in the mammalian brain
-
Feliciano, D. M., Bordey, A. & Bonfanti, L. Noncanonical sites of adult neurogenesis in the mammalian brain. Cold Spring Harb. Perspect. Biol. 7, a018846 (2015).
-
(2015)
Cold Spring Harb. Perspect. Biol.
, vol.7
, pp. a018846
-
-
Feliciano, D.M.1
Bordey, A.2
Bonfanti, L.3
-
9
-
-
77958605856
-
Epigenetic choreographers of neurogenesis in the adult mammalian brain
-
Ma, D. K., et al. Epigenetic choreographers of neurogenesis in the adult mammalian brain. Nat. Neurosci. 13, 1338-1344 (2010).
-
(2010)
Nat. Neurosci.
, vol.13
, pp. 1338-1344
-
-
Ma, D.K.1
-
10
-
-
77952678006
-
Epigenetic control of neural precursor cell fate during development
-
Hirabayashi, Y. & Gotoh, Y. Epigenetic control of neural precursor cell fate during development. Nat. Rev. Neurosci. 11, 377-388 (2010).
-
(2010)
Nat. Rev. Neurosci.
, vol.11
, pp. 377-388
-
-
Hirabayashi, Y.1
Gotoh, Y.2
-
12
-
-
0037322318
-
Neurons from radial glia: The consequences of asymmetric inheritance
-
Fishell, G. & Kriegstein, A. R. Neurons from radial glia: the consequences of asymmetric inheritance. Curr. Opin. Neurobiol. 13, 34-41 (2003).
-
(2003)
Curr. Opin. Neurobiol.
, vol.13
, pp. 34-41
-
-
Fishell, G.1
Kriegstein, A.R.2
-
13
-
-
0038304475
-
Radial glia diversity: A matter of cell fate
-
Kriegstein, A. R. & Gotz, M. Radial glia diversity: a matter of cell fate. Glia 43, 37-43 (2003).
-
(2003)
Glia
, vol.43
, pp. 37-43
-
-
Kriegstein, A.R.1
Gotz, M.2
-
14
-
-
0037092422
-
Dividing precursor cells of the embryonic cortical ventricular zone have morphological and molecular characteristics of radial glia
-
Noctor, S. C., et al. Dividing precursor cells of the embryonic cortical ventricular zone have morphological and molecular characteristics of radial glia. J. Neurosci. 22, 3161-3173 (2002).
-
(2002)
J. Neurosci.
, vol.22
, pp. 3161-3173
-
-
Noctor, S.C.1
-
15
-
-
0035173885
-
Characterization of CNS precursor subtypes and radial glia
-
Hartfuss, E., Galli, R., Heins, N. & Gotz, M. Characterization of CNS precursor subtypes and radial glia. Dev. Biol. 229, 15-30 (2001).
-
(2001)
Dev. Biol.
, vol.229
, pp. 15-30
-
-
Hartfuss, E.1
Galli, R.2
Heins, N.3
Gotz, M.4
-
16
-
-
36448947971
-
Specification of CNS glia from neural stem cells in the embryonic neuroepithelium
-
Kessaris, N., Pringle, N. & Richardson, W. D. Specification of CNS glia from neural stem cells in the embryonic neuroepithelium. Phil. Trans. R. Soc. B 363, 71-85 (2008).
-
(2008)
Phil. Trans. R. Soc. B
, vol.363
, pp. 71-85
-
-
Kessaris, N.1
Pringle, N.2
Richardson, W.D.3
-
17
-
-
67651036549
-
The glial nature of embryonic and adult neural stem cells
-
Kriegstein, A. & Alvarez-Buylla, A. The glial nature of embryonic and adult neural stem cells. Annu. Rev. Neurosci. 32, 149-184 (2009).
-
(2009)
Annu. Rev. Neurosci.
, vol.32
, pp. 149-184
-
-
Kriegstein, A.1
Alvarez-Buylla, A.2
-
18
-
-
84912527821
-
Neurogenesis in the embryonic and adult brain: Same regulators, different roles
-
Urban, N. & Guillemot, F. Neurogenesis in the embryonic and adult brain: same regulators, different roles. Front. Cell Neurosci. 8, 396 (2014).
-
(2014)
Front. Cell Neurosci.
, vol.8
, pp. 396
-
-
Urban, N.1
Guillemot, F.2
-
19
-
-
84928704364
-
Slowly dividing neural progenitors are an embryonic origin of adult neural stem cells
-
Furutachi, S., et al. Slowly dividing neural progenitors are an embryonic origin of adult neural stem cells. Nat. Neurosci. 18, 657-665 (2015).
-
(2015)
Nat. Neurosci.
, vol.18
, pp. 657-665
-
-
Furutachi, S.1
-
20
-
-
84934984011
-
Embryonic origin of postnatal neural stem cells
-
Fuentealba, L. C., et al. Embryonic origin of postnatal neural stem cells. Cell 161, 1644-1655 (2015).
-
(2015)
Cell
, vol.161
, pp. 1644-1655
-
-
Fuentealba, L.C.1
-
21
-
-
84949099666
-
Latent tri-lineage potential of adult hippocampal neural stem cells revealed by Nf1 inactivation
-
Sun, G. J., et al. Latent tri-lineage potential of adult hippocampal neural stem cells revealed by Nf1 inactivation. Nat. Neurosci. 18, 1722-1724 (2015).
-
(2015)
Nat. Neurosci.
, vol.18
, pp. 1722-1724
-
-
Sun, G.J.1
-
22
-
-
0035320035
-
A unified hypothesis on the lineage of neural stem cells
-
Alvarez-Buylla, A., Garcia-Verdugo, J. M. & Tramontin, A. D. A unified hypothesis on the lineage of neural stem cells. Nat. Rev. Neurosci. 2, 287-293 (2001).
-
(2001)
Nat. Rev. Neurosci.
, vol.2
, pp. 287-293
-
-
Alvarez-Buylla, A.1
Garcia-Verdugo, J.M.2
Tramontin, A.D.3
-
23
-
-
0035833068
-
Adult neurogenesis produces a large pool of new granule cells in the dentate gyrus
-
Cameron, H. A. & McKay, R. D. Adult neurogenesis produces a large pool of new granule cells in the dentate gyrus. J. Comp. Neurol. 435, 406-417 (2001).
-
(2001)
J. Comp. Neurol.
, vol.435
, pp. 406-417
-
-
Cameron, H.A.1
McKay, R.D.2
-
24
-
-
84904638995
-
Functions and dysfunctions of adult hippocampal neurogenesis
-
Christian, K. M., Song, H. & Ming, G. L. Functions and dysfunctions of adult hippocampal neurogenesis. Annu. Rev. Neurosci. 37, 243-262 (2014).
-
(2014)
Annu. Rev. Neurosci.
, vol.37
, pp. 243-262
-
-
Christian, K.M.1
Song, H.2
Ming, G.L.3
-
25
-
-
39149107803
-
Mechanisms and functional implications of adult neurogenesis
-
Zhao, C., Deng, W. & Gage, F. H. Mechanisms and functional implications of adult neurogenesis. Cell 132, 645-660 (2008).
-
(2008)
Cell
, vol.132
, pp. 645-660
-
-
Zhao, C.1
Deng, W.2
Gage, F.H.3
-
26
-
-
0022540321
-
CpG-rich islands and the function of DNA methylation
-
Bird, A. P. CpG-rich islands and the function of DNA methylation. Nature 321, 209-213 (1986).
-
(1986)
Nature
, vol.321
, pp. 209-213
-
-
Bird, A.P.1
-
27
-
-
80053270332
-
Neuronal activity modifies the DNA methylation landscape in the adult brain
-
Guo, J. U., et al. Neuronal activity modifies the DNA methylation landscape in the adult brain. Nat. Neurosci. 14, 1345-1351 (2011).
-
(2011)
Nat. Neurosci.
, vol.14
, pp. 1345-1351
-
-
Guo, J.U.1
-
28
-
-
0033753779
-
The DNA methyltransferases of mammals
-
Bestor, T. H. The DNA methyltransferases of mammals. Hum. Mol. Genet. 9, 2395-2402 (2000).
-
(2000)
Hum. Mol. Genet.
, vol.9
, pp. 2395-2402
-
-
Bestor, T.H.1
-
29
-
-
0028267714
-
Expression of DNA methyltransferase gene in mature and immature neurons as well as proliferating cells in mice
-
Goto, K., et al. Expression of DNA methyltransferase gene in mature and immature neurons as well as proliferating cells in mice. Differentiation 56, 39-44 (1994).
-
(1994)
Differentiation
, vol.56
, pp. 39-44
-
-
Goto, K.1
-
30
-
-
16444381345
-
Dynamic expression of de novo DNA methyltransferases Dnmt3a and Dnmt3b in the central nervous system
-
Feng, J., Chang, H., Li, E. & Fan, G. Dynamic expression of de novo DNA methyltransferases Dnmt3a and Dnmt3b in the central nervous system. J. Neurosci. Res. 79, 734-746 (2005).
-
(2005)
J. Neurosci. Res.
, vol.79
, pp. 734-746
-
-
Feng, J.1
Chang, H.2
Li, E.3
Fan, G.4
-
31
-
-
0033615717
-
DNA methyltransferases Dnmt3a and Dnmt3b are essential for de novo methylation and mammalian development
-
Okano, M., Bell, D. W., Haber, D. A. & Li, E. DNA methyltransferases Dnmt3a and Dnmt3b are essential for de novo methylation and mammalian development. Cell 99, 247-257 (1999).
-
(1999)
Cell
, vol.99
, pp. 247-257
-
-
Okano, M.1
Bell, D.W.2
Haber, D.A.3
Li, E.4
-
32
-
-
0026708177
-
Targeted mutation of the DNA methyltransferase gene results in embryonic lethality
-
Li, E., Bestor, T. H. & Jaenisch, R. Targeted mutation of the DNA methyltransferase gene results in embryonic lethality. Cell 69, 915-926 (1992).
-
(1992)
Cell
, vol.69
, pp. 915-926
-
-
Li, E.1
Bestor, T.H.2
Jaenisch, R.3
-
33
-
-
24344472335
-
DNA methylation controls the timing of astrogliogenesis through regulation of JAK-STAT signaling
-
Fan, G., et al. DNA methylation controls the timing of astrogliogenesis through regulation of JAK-STAT signaling. Development 132, 3345-3356 (2005).
-
(2005)
Development
, vol.132
, pp. 3345-3356
-
-
Fan, G.1
-
34
-
-
34250643467
-
Ablation of de novo DNA methyltransferase Dnmt3a in the nervous system leads to neuromuscular defects and shortened lifespan
-
Nguyen, S., Meletis, K., Fu, D., Jhaveri, S. & Jaenisch, R. Ablation of de novo DNA methyltransferase Dnmt3a in the nervous system leads to neuromuscular defects and shortened lifespan. Dev. Dyn. 236, 1663-1676 (2007).
-
(2007)
Dev. Dyn.
, vol.236
, pp. 1663-1676
-
-
Nguyen, S.1
Meletis, K.2
Fu, D.3
Jhaveri, S.4
Jaenisch, R.5
-
35
-
-
77954842322
-
Dnmt3a-dependent nonpromoter DNA methylation facilitates transcription of neurogenic genes
-
Wu, H., et al. Dnmt3a-dependent nonpromoter DNA methylation facilitates transcription of neurogenic genes. Science 329, 444-448 (2010).
-
(2010)
Science
, vol.329
, pp. 444-448
-
-
Wu, H.1
-
36
-
-
84930486044
-
Role of DNMT3B in the regulation of early neural and neural crest specifiers
-
Martins-Taylor, K., Schroeder, D. I., LaSalle, J. M., Lalande, M. & Xu, R. H. Role of DNMT3B in the regulation of early neural and neural crest specifiers. Epigenetics 7, 71-82 (2012).
-
(2012)
Epigenetics
, vol.7
, pp. 71-82
-
-
Martins-Taylor, K.1
Schroeder, D.I.2
LaSalle, J.M.3
Lalande, M.4
Xu, R.H.5
-
37
-
-
0031577334
-
DNA (cytosine-5)-methyltransferases in mouse cells and tissues. Studies with a mechanismbased probe
-
Yoder, J. A., Soman, N. S., Verdine, G. L. & Bestor, T. H. DNA (cytosine-5)-methyltransferases in mouse cells and tissues. Studies with a mechanismbased probe. J. Mol. Biol. 270, 385-395 (1997).
-
(1997)
J. Mol. Biol.
, vol.270
, pp. 385-395
-
-
Yoder, J.A.1
Soman, N.S.2
Verdine, G.L.3
Bestor, T.H.4
-
38
-
-
84893740377
-
Distribution, recognition and regulation of non-CpG methylation in the adult mammalian brain
-
Guo, J. U., et al. Distribution, recognition and regulation of non-CpG methylation in the adult mammalian brain. Nat. Neurosci. 17, 215-222 (2014).
-
(2014)
Nat. Neurosci.
, vol.17
, pp. 215-222
-
-
Guo, J.U.1
-
39
-
-
84879663784
-
Global epigenomic reconfiguration during mammalian brain development
-
Lister, R., et al. Global epigenomic reconfiguration during mammalian brain development. Science 341, 1237905 (2013).
-
(2013)
Science
, vol.341
, pp. 1237905
-
-
Lister, R.1
-
40
-
-
84928533445
-
Disruption of DNA-methylationdependent long gene repression in Rett syndrome
-
Gabel, H. W., et al. Disruption of DNA-methylationdependent long gene repression in Rett syndrome. Nature 522, 89-93 (2015).
-
(2015)
Nature
, vol.522
, pp. 89-93
-
-
Gabel, H.W.1
-
41
-
-
84928534828
-
MeCP2 binds to non-CG methylated DNA as neurons mature, influencing transcription and the timing of onset for Rett syndrome
-
Chen, L., et al. MeCP2 binds to non-CG methylated DNA as neurons mature, influencing transcription and the timing of onset for Rett syndrome. Proc. Natl Acad. Sci. USA 112, 5509-5514 (2015).
-
(2015)
Proc. Natl Acad. Sci. USA
, vol.112
, pp. 5509-5514
-
-
Chen, L.1
-
42
-
-
84931066427
-
Epigenomic signatures of neuronal diversity in the mammalian brain
-
Mo, A., et al. Epigenomic signatures of neuronal diversity in the mammalian brain. Neuron 86, 1369-1384 (2015).
-
(2015)
Neuron
, vol.86
, pp. 1369-1384
-
-
Mo, A.1
-
43
-
-
0037636512
-
Mice lacking methyl-CpG binding protein 1 have deficits in adult neurogenesis and hippocampal function
-
Zhao, X., et al. Mice lacking methyl-CpG binding protein 1 have deficits in adult neurogenesis and hippocampal function. Proc. Natl Acad. Sci. USA 100, 6777-6782 (2003).
-
(2003)
Proc. Natl Acad. Sci. USA
, vol.100
, pp. 6777-6782
-
-
Zhao, X.1
-
44
-
-
55549108710
-
Epigenetic regulation of the stem cell mitogen Fgf-2 by Mbd1 in adult neural stem/progenitor cells
-
Li, X., et al. Epigenetic regulation of the stem cell mitogen Fgf-2 by Mbd1 in adult neural stem/progenitor cells. J. Biol. Chem. 283, 27644-27652 (2008).
-
(2008)
J. Biol. Chem.
, vol.283
, pp. 27644-27652
-
-
Li, X.1
-
45
-
-
0026747761
-
Purification, sequence, and cellular localization of a novel chromosomal protein that binds to methylated DNA
-
Lewis, J. D., et al. Purification, sequence, and cellular localization of a novel chromosomal protein that binds to methylated DNA. Cell 69, 905-914 (1992).
-
(1992)
Cell
, vol.69
, pp. 905-914
-
-
Lewis, J.D.1
-
46
-
-
84871563384
-
MeCP2 binds to 5hmC enriched within active genes and accessible chromatin in the nervous system
-
Mellen, M., Ayata, P., Dewell, S., Kriaucionis, S. & Heintz, N. MeCP2 binds to 5hmC enriched within active genes and accessible chromatin in the nervous system. Cell 151, 1417-1430 (2012).
-
(2012)
Cell
, vol.151
, pp. 1417-1430
-
-
Mellen, M.1
Ayata, P.2
Dewell, S.3
Kriaucionis, S.4
Heintz, N.5
-
47
-
-
34250333455
-
Mecp2 deficiency leads to delayed maturation and altered gene expression in hippocampal neurons
-
Smrt, R. D., et al. Mecp2 deficiency leads to delayed maturation and altered gene expression in hippocampal neurons. Neurobiol. Dis. 27, 77-89 (2007).
-
(2007)
Neurobiol. Dis.
, vol.27
, pp. 77-89
-
-
Smrt, R.D.1
-
48
-
-
0242332183
-
Derepression of BDNF transcription involves calcium-dependent phosphorylation of MeCP2
-
Chen, W. G., et al. Derepression of BDNF transcription involves calcium-dependent phosphorylation of MeCP2. Science 302, 885-889 (2003).
-
(2003)
Science
, vol.302
, pp. 885-889
-
-
Chen, W.G.1
-
49
-
-
0242300612
-
DNA methylation-related chromatin remodeling in activity-dependent Bdnf gene regulation
-
Martinowich, K., et al. DNA methylation-related chromatin remodeling in activity-dependent Bdnf gene regulation. Science 302, 890-893 (2003).
-
(2003)
Science
, vol.302
, pp. 890-893
-
-
Martinowich, K.1
-
50
-
-
84884692057
-
DNA methylation presents distinct binding sites for human transcription factors
-
Hu, S., et al. DNA methylation presents distinct binding sites for human transcription factors. eLife 2, e00726 (2013).
-
(2013)
ELife
, vol.2
, pp. e00726
-
-
Hu, S.1
-
51
-
-
84872498439
-
Signaling mechanisms regulating adult neural stem cells and neurogenesis
-
Faigle, R. & Song, H. Signaling mechanisms regulating adult neural stem cells and neurogenesis. Biochim. Biophys. Acta 1830, 2435-2448 (2013).
-
(2013)
Biochim. Biophys. Acta
, vol.1830
, pp. 2435-2448
-
-
Faigle, R.1
Song, H.2
-
52
-
-
66149146320
-
Conversion of 5-methylcytosine to 5-hydroxymethylcytosine in mammalian DNA by MLL partner TET1
-
Tahiliani, M., et al. Conversion of 5-methylcytosine to 5-hydroxymethylcytosine in mammalian DNA by MLL partner TET1. Science 324, 930-935 (2009).
-
(2009)
Science
, vol.324
, pp. 930-935
-
-
Tahiliani, M.1
-
53
-
-
77956189495
-
Role of Tet proteins in 5mC to 5hmC conversion, ES-cell self-renewal and inner cell mass specification
-
Ito, S., et al. Role of Tet proteins in 5mC to 5hmC conversion, ES-cell self-renewal and inner cell mass specification. Nature 466, 1129-1133 (2010).
-
(2010)
Nature
, vol.466
, pp. 1129-1133
-
-
Ito, S.1
-
54
-
-
80052495940
-
Tet-mediated formation of 5-carboxylcytosine and its excision by TDG in mammalian DNA
-
He, Y. F., et al. Tet-mediated formation of 5-carboxylcytosine and its excision by TDG in mammalian DNA. Science 333, 1303-1307 (2011).
-
(2011)
Science
, vol.333
, pp. 1303-1307
-
-
He, Y.F.1
-
55
-
-
80052461558
-
Tet proteins can convert 5-methylcytosine to 5-formylcytosine and 5-carboxylcytosine
-
Ito, S., et al. Tet proteins can convert 5-methylcytosine to 5-formylcytosine and 5-carboxylcytosine. Science 333, 1300-1303 (2011).
-
(2011)
Science
, vol.333
, pp. 1300-1303
-
-
Ito, S.1
-
56
-
-
79955538247
-
Hydroxylation of 5-methylcytosine by TET1 promotes active DNA demethylation in the adult brain
-
Guo, J. U., Su, Y., Zhong, C., Ming, G. L. & Song, H. Hydroxylation of 5-methylcytosine by TET1 promotes active DNA demethylation in the adult brain. Cell 145, 423-434 (2011).
-
(2011)
Cell
, vol.145
, pp. 423-434
-
-
Guo, J.U.1
Su, Y.2
Zhong, C.3
Ming, G.L.4
Song, H.5
-
57
-
-
60749094831
-
Neuronal activity-induced Gadd45b promotes epigenetic DNA demethylation and adult neurogenesis
-
Ma, D. K., et al. Neuronal activity-induced Gadd45b promotes epigenetic DNA demethylation and adult neurogenesis. Science 323, 1074-1077 (2009).
-
(2009)
Science
, vol.323
, pp. 1074-1077
-
-
Ma, D.K.1
-
58
-
-
57649196594
-
DNA demethylation in zebrafish involves the coupling of a deaminase, a glycosylase, and gadd45
-
Rai, K., et al. DNA demethylation in zebrafish involves the coupling of a deaminase, a glycosylase, and gadd45. Cell 135, 1201-1212 (2008).
-
(2008)
Cell
, vol.135
, pp. 1201-1212
-
-
Rai, K.1
-
59
-
-
33846933274
-
Gadd45a promotes epigenetic gene activation by repair-mediated DNA demethylation
-
Barreto, G., et al. Gadd45a promotes epigenetic gene activation by repair-mediated DNA demethylation. Nature 445, 671-675 (2007).
-
(2007)
Nature
, vol.445
, pp. 671-675
-
-
Barreto, G.1
-
60
-
-
84908542111
-
Decoding neural transcriptomes and epigenomes via high-throughput sequencing
-
Shin, J., Ming, G. L. & Song, H. Decoding neural transcriptomes and epigenomes via high-throughput sequencing. Nat. Neurosci. 17, 1463-1475 (2014).
-
(2014)
Nat. Neurosci.
, vol.17
, pp. 1463-1475
-
-
Shin, J.1
Ming, G.L.2
Song, H.3
-
61
-
-
84874252793
-
Dynamics of 5-hydroxymethylcytosine and chromatin marks in mammalian neurogenesis
-
Hahn, M. A., et al. Dynamics of 5-hydroxymethylcytosine and chromatin marks in mammalian neurogenesis. Cell Rep. 3, 291-300 (2013).
-
(2013)
Cell Rep.
, vol.3
, pp. 291-300
-
-
Hahn, M.A.1
-
62
-
-
82255192294
-
5-hmC-mediated epigenetic dynamics during postnatal neurodevelopment and aging
-
Szulwach, K. E., et al. 5-hmC-mediated epigenetic dynamics during postnatal neurodevelopment and aging. Nat. Neurosci. 14, 1607-1616 (2011).
-
(2011)
Nat. Neurosci.
, vol.14
, pp. 1607-1616
-
-
Szulwach, K.E.1
-
63
-
-
84876907152
-
Genome-wide profiling of 5-formylcytosine reveals its roles in epigenetic priming
-
Song, C. X., et al. Genome-wide profiling of 5-formylcytosine reveals its roles in epigenetic priming. Cell 153, 678-691 (2013).
-
(2013)
Cell
, vol.153
, pp. 678-691
-
-
Song, C.X.1
-
64
-
-
84861990517
-
Base-resolution analysis of 5-hydroxymethylcytosine in the mammalian genome
-
Yu, M., et al. Base-resolution analysis of 5-hydroxymethylcytosine in the mammalian genome. Cell 149, 1368-1380 (2012).
-
(2012)
Cell
, vol.149
, pp. 1368-1380
-
-
Yu, M.1
-
65
-
-
84937736036
-
5-Formylcytosine can be a stable DNA modification in mammals
-
Bachman, M., et al. 5-Formylcytosine can be a stable DNA modification in mammals. Nat. Chem. Biol. 11, 555-557 (2015).
-
(2015)
Nat. Chem. Biol.
, vol.11
, pp. 555-557
-
-
Bachman, M.1
-
66
-
-
84874771985
-
Dynamic readers for 5-(hydroxy) methylcytosine and its oxidized derivatives
-
Spruijt, C. G., et al. Dynamic readers for 5-(hydroxy) methylcytosine and its oxidized derivatives. Cell 152, 1146-1159 (2013).
-
(2013)
Cell
, vol.152
, pp. 1146-1159
-
-
Spruijt, C.G.1
-
67
-
-
84860389582
-
Cooperative DNA and histone binding by Uhrf2 links the two major repressive epigenetic pathways
-
Pichler, G., et al. Cooperative DNA and histone binding by Uhrf2 links the two major repressive epigenetic pathways. J. Cell. Biochem. 112, 2585-2593 (2011).
-
(2011)
J. Cell. Biochem.
, vol.112
, pp. 2585-2593
-
-
Pichler, G.1
-
68
-
-
84893373754
-
Distinct roles of the methylcytosine oxidases Tet1 and Tet2 in mouse embryonic stem cells
-
Huang, Y., et al. Distinct roles of the methylcytosine oxidases Tet1 and Tet2 in mouse embryonic stem cells. Proc. Natl Acad. Sci. USA 111, 1361-1366 (2014).
-
(2014)
Proc. Natl Acad. Sci. USA
, vol.111
, pp. 1361-1366
-
-
Huang, Y.1
-
69
-
-
84881178902
-
Tet1 regulates adult hippocampal neurogenesis and cognition
-
Zhang, R. R., et al. Tet1 regulates adult hippocampal neurogenesis and cognition. Cell Stem Cell 13, 237-245 (2013).
-
(2013)
Cell Stem Cell
, vol.13
, pp. 237-245
-
-
Zhang, R.R.1
-
70
-
-
84870883633
-
Tet3 CXXC domain and dioxygenase activity cooperatively regulate key genes for Xenopus eye and neural development
-
Xu, Y., et al. Tet3 CXXC domain and dioxygenase activity cooperatively regulate key genes for Xenopus eye and neural development. Cell 151, 1200-1213 (2012).
-
(2012)
Cell
, vol.151
, pp. 1200-1213
-
-
Xu, Y.1
-
71
-
-
77952887349
-
Epigenetics hippocampal neurogenesis, and neuropsychiatric disorders: Unraveling the genome to understand the mind
-
Hsieh, J. & Eisch, A. J. Epigenetics, hippocampal neurogenesis, and neuropsychiatric disorders: unraveling the genome to understand the mind. Neurobiol. Dis. 39, 73-84 (2010).
-
(2010)
Neurobiol. Dis.
, vol.39
, pp. 73-84
-
-
Hsieh, J.1
Eisch, A.J.2
-
72
-
-
84883012277
-
Genome-wide loss of 5-hmC is a novel epigenetic feature of Huntingtons disease
-
Wang, F., et al. Genome-wide loss of 5-hmC is a novel epigenetic feature of Huntingtons disease. Hum. Mol. Genet. 22, 3641-3653 (2013).
-
(2013)
Hum. Mol. Genet.
, vol.22
, pp. 3641-3653
-
-
Wang, F.1
-
73
-
-
77958524817
-
Dynamic epigenetic regulation in neurons: Enzymes, stimuli and signaling pathways
-
Riccio, A. Dynamic epigenetic regulation in neurons: enzymes, stimuli and signaling pathways. Nat. Neurosci. 13, 1330-1337 (2010).
-
(2010)
Nat. Neurosci.
, vol.13
, pp. 1330-1337
-
-
Riccio, A.1
-
74
-
-
2542453750
-
Querkopf a histone acetyltransferase, is essential for embryonic neurogenesis
-
Thomas, T. & Voss, A. K. Querkopf, a histone acetyltransferase, is essential for embryonic neurogenesis. Front. Biosci. 9, 24-31 (2004).
-
(2004)
Front. Biosci.
, vol.9
, pp. 24-31
-
-
Thomas, T.1
Voss, A.K.2
-
75
-
-
84859893371
-
Histone methylation: A dynamic mark in health, disease and inheritance
-
Greer, E. L. & Shi, Y. Histone methylation: a dynamic mark in health, disease and inheritance. Nat. Rev. Genet. 13, 343-357 (2012).
-
(2012)
Nat. Rev. Genet.
, vol.13
, pp. 343-357
-
-
Greer, E.L.1
Shi, Y.2
-
76
-
-
33845799903
-
Polycomb silencing mechanisms and the management of genomic programmes
-
Schwartz, Y. B. & Pirrotta, V. Polycomb silencing mechanisms and the management of genomic programmes. Nat. Rev. Genet. 8, 9-22 (2007).
-
(2007)
Nat. Rev. Genet.
, vol.8
, pp. 9-22
-
-
Schwartz, Y.B.1
Pirrotta, V.2
-
77
-
-
81855212627
-
Trithorax group proteins: Switching genes on and keeping them active
-
Schuettengruber, B., Martinez, A. M., Iovino, N. & Cavalli, G. Trithorax group proteins: switching genes on and keeping them active. Nat. Rev. Mol. Cell Biol. 12, 799-814 (2011).
-
(2011)
Nat. Rev. Mol. Cell Biol.
, vol.12
, pp. 799-814
-
-
Schuettengruber, B.1
Martinez, A.M.2
Iovino, N.3
Cavalli, G.4
-
78
-
-
69949085080
-
Polycomb limits the neurogenic competence of neural precursor cells to promote astrogenic fate transition
-
Hirabayashi, Y., et al. Polycomb limits the neurogenic competence of neural precursor cells to promote astrogenic fate transition. Neuron 63, 600-613 (2009).
-
(2009)
Neuron
, vol.63
, pp. 600-613
-
-
Hirabayashi, Y.1
-
79
-
-
77957680712
-
Ezh2, the histone methyltransferase of PRC2, regulates the balance between self-renewal and differentiation in the cerebral cortex
-
Pereira, J. D., et al. Ezh2, the histone methyltransferase of PRC2, regulates the balance between self-renewal and differentiation in the cerebral cortex. Proc. Natl Acad. Sci. USA 107, 15957-15962 (2010).
-
(2010)
Proc. Natl Acad. Sci. USA
, vol.107
, pp. 15957-15962
-
-
Pereira, J.D.1
-
80
-
-
34249907279
-
ShRNA knockdown of Bmi-1 reveals a critical role for p21-Rb pathway in NSC selfrenewal during development
-
Fasano, C. A., et al. shRNA knockdown of Bmi-1 reveals a critical role for p21-Rb pathway in NSC selfrenewal during development. Cell Stem Cell 1, 87-99 (2007).
-
(2007)
Cell Stem Cell
, vol.1
, pp. 87-99
-
-
Fasano, C.A.1
-
81
-
-
63649125648
-
Chromatin remodelling factor Mll1 is essential for neurogenesis from postnatal neural stem cells
-
Lim, D. A., et al. Chromatin remodelling factor Mll1 is essential for neurogenesis from postnatal neural stem cells. Nature 458, 529-533 (2009).
-
(2009)
Nature
, vol.458
, pp. 529-533
-
-
Lim, D.A.1
-
82
-
-
33646070846
-
A bivalent chromatin structure marks key developmental genes in embryonic stem cells
-
Bernstein, B. E., et al. A bivalent chromatin structure marks key developmental genes in embryonic stem cells. Cell 125, 315-326 (2006).
-
(2006)
Cell
, vol.125
, pp. 315-326
-
-
Bernstein, B.E.1
-
83
-
-
51649129596
-
Lineage-specific polycomb targets and de novo DNA methylation define restriction and potential of neuronal progenitors
-
Mohn, F., et al. Lineage-specific polycomb targets and de novo DNA methylation define restriction and potential of neuronal progenitors. Mol. Cell 30, 755-766 (2008).
-
(2008)
Mol. Cell
, vol.30
, pp. 755-766
-
-
Mohn, F.1
-
84
-
-
77950675541
-
Histone demethylase LSD1 regulates neural stem cell proliferation
-
Sun, G., et al. Histone demethylase LSD1 regulates neural stem cell proliferation. Mol. Cell. Biol. 30, 1997-2005 (2010).
-
(2010)
Mol. Cell. Biol.
, vol.30
, pp. 1997-2005
-
-
Sun, G.1
-
85
-
-
84925199744
-
A specific LSD1/KDM1A isoform regulates neuronal differentiation through H3K9 demethylation
-
Laurent, B., et al. A specific LSD1/KDM1A isoform regulates neuronal differentiation through H3K9 demethylation. Mol. Cell 57, 957-970 (2015).
-
(2015)
Mol. Cell
, vol.57
, pp. 957-970
-
-
Laurent, B.1
-
86
-
-
36248990248
-
SMRT-mediated repression of an H3K27 demethylase in progression from neural stem cell to neuron
-
Jepsen, K., et al. SMRT-mediated repression of an H3K27 demethylase in progression from neural stem cell to neuron. Nature 450, 415-419 (2007).
-
(2007)
Nature
, vol.450
, pp. 415-419
-
-
Jepsen, K.1
-
87
-
-
34547924046
-
HATs and HDACs: From structure, function and regulation to novel strategies for therapy and prevention
-
Yang, X. J. & Seto, E. HATs and HDACs: from structure, function and regulation to novel strategies for therapy and prevention. Oncogene 26, 5310-5318 (2007).
-
(2007)
Oncogene
, vol.26
, pp. 5310-5318
-
-
Yang, X.J.1
Seto, E.2
-
88
-
-
33750962553
-
The transcriptional coactivator Querkopf controls adult neurogenesis
-
Merson, T. D., et al. The transcriptional coactivator Querkopf controls adult neurogenesis. J. Neurosci. 26, 11359-11370 (2006).
-
(2006)
J. Neurosci.
, vol.26
, pp. 11359-11370
-
-
Merson, T.D.1
-
89
-
-
49449094483
-
Histone deacetylases 1 and 2 are expressed at distinct stages of neuro-glial development
-
MacDonald, J. L. & Roskams, A. J. Histone deacetylases 1 and 2 are expressed at distinct stages of neuro-glial development. Dev. Dyn. 237, 2256-2267 (2008).
-
(2008)
Dev. Dyn.
, vol.237
, pp. 2256-2267
-
-
MacDonald, J.L.1
Roskams, A.J.2
-
90
-
-
34848818037
-
Orphan nuclear receptor TLX recruits histone deacetylases to repress transcription and regulate neural stem cell proliferation
-
Sun, G., Yu, R. T., Evans, R. M. & Shi, Y. Orphan nuclear receptor TLX recruits histone deacetylases to repress transcription and regulate neural stem cell proliferation. Proc. Natl Acad. Sci. USA 104, 15282-15287 (2007).
-
(2007)
Proc. Natl Acad. Sci. USA
, vol.104
, pp. 15282-15287
-
-
Sun, G.1
Yu, R.T.2
Evans, R.M.3
Shi, Y.4
-
91
-
-
84922343890
-
Ankrd11 is a chromatin regulator involved in autism that is essential for neural development
-
Gallagher, D., et al. Ankrd11 is a chromatin regulator involved in autism that is essential for neural development. Dev. Cell 32, 31-42 (2015).
-
(2015)
Dev. Cell
, vol.32
, pp. 31-42
-
-
Gallagher, D.1
-
92
-
-
50549086376
-
Histone deacetylases control neurogenesis in embryonic brain by inhibition of BMP2/4 signaling
-
Shaked, M., et al. Histone deacetylases control neurogenesis in embryonic brain by inhibition of BMP2/4 signaling. PLoS ONE 3, e2668 (2008).
-
(2008)
PLoS ONE
, vol.3
, pp. e2668
-
-
Shaked, M.1
-
93
-
-
9344252804
-
Histone deacetylase inhibition-mediated neuronal differentiation of multipotent adult neural progenitor cells
-
Hsieh, J., Nakashima, K., Kuwabara, T., Mejia, E. & Gage, F. H. Histone deacetylase inhibition-mediated neuronal differentiation of multipotent adult neural progenitor cells. Proc. Natl Acad. Sci. USA 101, 16659-16664 (2004).
-
(2004)
Proc. Natl Acad. Sci. USA
, vol.101
, pp. 16659-16664
-
-
Hsieh, J.1
Nakashima, K.2
Kuwabara, T.3
Mejia, E.4
Gage, F.H.5
-
94
-
-
84864996189
-
Mechanistic insights into the regulation of metabolic enzymes by acetylation
-
Xiong, Y. & Guan, K. L. Mechanistic insights into the regulation of metabolic enzymes by acetylation. J. Cell Biol. 198, 155-164 (2012).
-
(2012)
J. Cell Biol.
, vol.198
, pp. 155-164
-
-
Xiong, Y.1
Guan, K.L.2
-
96
-
-
3042822087
-
Dopamine depletion impairs precursor cell proliferation in Parkinson disease
-
Hoglinger, G. U., et al. Dopamine depletion impairs precursor cell proliferation in Parkinson disease. Nat. Neurosci. 7, 726-735 (2004).
-
(2004)
Nat. Neurosci.
, vol.7
, pp. 726-735
-
-
Hoglinger, G.U.1
-
97
-
-
0034681471
-
Dopaminergic loss and inclusion body formation in a-synuclein mice: Implications for neurodegenerative disorders
-
Masliah, E., et al. Dopaminergic loss and inclusion body formation in a-synuclein mice: implications for neurodegenerative disorders. Science 287, 1265-1269 (2000).
-
(2000)
Science
, vol.287
, pp. 1265-1269
-
-
Masliah, E.1
-
98
-
-
40449139321
-
Neurodegeneration and motor dysfunction in a conditional model of Parkinsons disease
-
Nuber, S., et al. Neurodegeneration and motor dysfunction in a conditional model of Parkinsons disease. J. Neurosci. 28, 2471-2484 (2008).
-
(2008)
J. Neurosci.
, vol.28
, pp. 2471-2484
-
-
Nuber, S.1
-
99
-
-
77957794336
-
Impaired dopaminergic neurotransmission and microtubule-associated protein tau alterations in human LRRK2 transgenic mice
-
Melrose, H. L., et al. Impaired dopaminergic neurotransmission and microtubule-associated protein tau alterations in human LRRK2 transgenic mice. Neurobiol. Dis. 40, 503-517 (2010).
-
(2010)
Neurobiol. Dis.
, vol.40
, pp. 503-517
-
-
Melrose, H.L.1
-
100
-
-
27544507306
-
A-Synuclein cooperates with CSPa in preventing neurodegeneration
-
Chandra, S., Gallardo, G., Fernandez-Chacon, R., Schluter, O. M. & Sudhof, T. C. a-Synuclein cooperates with CSPa in preventing neurodegeneration. Cell 123, 383-396 (2005).
-
(2005)
Cell
, vol.123
, pp. 383-396
-
-
Chandra, S.1
Gallardo, G.2
Fernandez-Chacon, R.3
Schluter, O.M.4
Sudhof, T.C.5
-
101
-
-
84870015777
-
Role of a-synuclein in adult neurogenesis and neuronal maturation in the dentate gyrus
-
Winner, B., et al. Role of a-synuclein in adult neurogenesis and neuronal maturation in the dentate gyrus. J. Neurosci. 32, 16906-16916 (2012).
-
(2012)
J. Neurosci.
, vol.32
, pp. 16906-16916
-
-
Winner, B.1
-
102
-
-
77951842993
-
Methylation regulates a-synuclein expression and is decreased in Parkinsons disease patients brains
-
Jowaed, A., Schmitt, I., Kaut, O. & Wullner, U. Methylation regulates a-synuclein expression and is decreased in Parkinsons disease patients brains. J. Neurosci. 30, 6355-6359 (2010).
-
(2010)
J. Neurosci.
, vol.30
, pp. 6355-6359
-
-
Jowaed, A.1
Schmitt, I.2
Kaut, O.3
Wullner, U.4
-
103
-
-
78649652766
-
CpG demethylation enhances alpha-synuclein expression and affects the pathogenesis of Parkinsons disease
-
Matsumoto, L., et al. CpG demethylation enhances alpha-synuclein expression and affects the pathogenesis of Parkinsons disease. PLoS ONE 5, e15522 (2010).
-
(2010)
PLoS ONE
, vol.5
, pp. e15522
-
-
Matsumoto, L.1
-
104
-
-
79953178935
-
A-synuclein sequesters Dnmt1 from the nucleus: A novel mechanism for epigenetic alterations in Lewy body diseases
-
Desplats, P., et al. a-synuclein sequesters Dnmt1 from the nucleus: a novel mechanism for epigenetic alterations in Lewy body diseases. J. Biol. Chem. 286, 9031-9037 (2011).
-
(2011)
J. Biol. Chem.
, vol.286
, pp. 9031-9037
-
-
Desplats, P.1
-
105
-
-
79151473945
-
Adult neurogenesis and neurite outgrowth are impaired in LRRK2 G2019S mice
-
Winner, B., et al. Adult neurogenesis and neurite outgrowth are impaired in LRRK2 G2019S mice. Neurobiol. Dis. 41, 706-716 (2011).
-
(2011)
Neurobiol. Dis.
, vol.41
, pp. 706-716
-
-
Winner, B.1
-
106
-
-
84924455094
-
LRRK2 overexpression alters glutamatergic presynaptic plasticity, striatal dopamine tone, postsynaptic signal transduction, motor activity and memory
-
Beccano-Kelly, D. A., et al. LRRK2 overexpression alters glutamatergic presynaptic plasticity, striatal dopamine tone, postsynaptic signal transduction, motor activity and memory. Hum. Mol. Genet. 24, 1336-1349 (2015).
-
(2015)
Hum. Mol. Genet.
, vol.24
, pp. 1336-1349
-
-
Beccano-Kelly, D.A.1
-
107
-
-
84872394361
-
MicroRNA-205 regulates the expression of Parkinsons disease-related leucine-rich repeat kinase 2 protein
-
Cho, H. J., et al. MicroRNA-205 regulates the expression of Parkinsons disease-related leucine-rich repeat kinase 2 protein. Hum. Mol. Genet. 22, 608-620 (2013).
-
(2013)
Hum. Mol. Genet.
, vol.22
, pp. 608-620
-
-
Cho, H.J.1
-
108
-
-
0037135111
-
The amyloid hypothesis of Alzheimers disease: Progress and problems on the road to therapeutics
-
Hardy, J. & Selkoe, D. J. The amyloid hypothesis of Alzheimers disease: progress and problems on the road to therapeutics. Science 297, 353-356 (2002).
-
(2002)
Science
, vol.297
, pp. 353-356
-
-
Hardy, J.1
Selkoe, D.J.2
-
109
-
-
84908463972
-
Genetics of Alzheimers disease
-
Chouraki, V. & Seshadri, S. Genetics of Alzheimers disease. Adv. Genet. 87, 245-294 (2014).
-
(2014)
Adv. Genet.
, vol.87
, pp. 245-294
-
-
Chouraki, V.1
Seshadri, S.2
-
110
-
-
4444302117
-
Molecular genetics of late-onset Alzheimers disease
-
Kamboh, M. I. Molecular genetics of late-onset Alzheimers disease. Ann. Hum. Genet. 68, 381-404 (2004).
-
(2004)
Ann. Hum. Genet.
, vol.68
, pp. 381-404
-
-
Kamboh, M.I.1
-
111
-
-
0028985574
-
Alzheimer-type neuropathology in transgenic mice overexpressing V717F β-amyloid precursor protein
-
Games, D., et al. Alzheimer-type neuropathology in transgenic mice overexpressing V717F β-amyloid precursor protein. Nature 373, 523-527 (1995).
-
(1995)
Nature
, vol.373
, pp. 523-527
-
-
Games, D.1
-
112
-
-
0029742199
-
Correlative memory deficits, Aβ elevation, and amyloid plaques in transgenic mice
-
Hsiao, K., et al. Correlative memory deficits, Aβ elevation, and amyloid plaques in transgenic mice. Science 274, 99-102 (1996).
-
(1996)
Science
, vol.274
, pp. 99-102
-
-
Hsiao, K.1
-
113
-
-
80055088590
-
Epigenetics in Alzheimers disease: A focus on DNA modifications
-
Coppieters, N. & Dragunow, M. Epigenetics in Alzheimers disease: a focus on DNA modifications. Curr. Pharm. Des. 17, 3398-3412 (2011).
-
(2011)
Curr. Pharm. Des.
, vol.17
, pp. 3398-3412
-
-
Coppieters, N.1
Dragunow, M.2
-
114
-
-
84878944565
-
Consistent decrease in global DNA methylation and hydroxymethylation in the hippocampus of Alzheimers disease patients
-
Chouliaras, L., et al. Consistent decrease in global DNA methylation and hydroxymethylation in the hippocampus of Alzheimers disease patients. Neurobiol. Aging 34, 2091-2099 (2013).
-
(2013)
Neurobiol. Aging
, vol.34
, pp. 2091-2099
-
-
Chouliaras, L.1
-
115
-
-
84919784465
-
Alzheimers disease: Early alterations in brain DNA methylation at ANK1, BIN1, RHBDF2 and other loci
-
De Jager, P. L., et al. Alzheimers disease: early alterations in brain DNA methylation at ANK1, BIN1, RHBDF2 and other loci. Nat. Neurosci. 17, 1156-1163 (2014).
-
(2014)
Nat. Neurosci.
, vol.17
, pp. 1156-1163
-
-
De Jager, P.L.1
-
116
-
-
0033945494
-
Presenilin-1 regulates neuronal differentiation during neurogenesis
-
Handler, M., Yang, X. & Shen, J. Presenilin-1 regulates neuronal differentiation during neurogenesis. Development 127, 2593-2606 (2000).
-
(2000)
Development
, vol.127
, pp. 2593-2606
-
-
Handler, M.1
Yang, X.2
Shen, J.3
-
117
-
-
84939186065
-
Presenilin-1 dependent neurogenesis regulates hippocampal learning and memory
-
Bonds, J. A., et al. Presenilin-1 dependent neurogenesis regulates hippocampal learning and memory. PLoS ONE 10, e0131266 (2015).
-
(2015)
PLoS ONE
, vol.10
, pp. e0131266
-
-
Bonds, J.A.1
-
118
-
-
84943583771
-
Epigenetic regulation of presenilin 1 and 2 in the cerebral cortex of mice during development
-
Kumar, A. & Thakur, M. K. Epigenetic regulation of presenilin 1 and 2 in the cerebral cortex of mice during development. Dev. Neurobiol. 75, 1165-1173 (2015).
-
(2015)
Dev. Neurobiol.
, vol.75
, pp. 1165-1173
-
-
Kumar, A.1
Thakur, M.K.2
-
119
-
-
70450257814
-
GABAergic interneuron dysfunction impairs hippocampal neurogenesis in adult apolipoprotein E4 knockin mice
-
Li, G., et al. GABAergic interneuron dysfunction impairs hippocampal neurogenesis in adult apolipoprotein E4 knockin mice. Cell Stem Cell 5, 634-645 (2009).
-
(2009)
Cell Stem Cell
, vol.5
, pp. 634-645
-
-
Li, G.1
-
120
-
-
84888157018
-
Epigenetic signature and enhancer activity of the human APOE gene
-
Yu, C. E., et al. Epigenetic signature and enhancer activity of the human APOE gene. Hum. Mol. Genet. 22, 5036-5047 (2013).
-
(2013)
Hum. Mol. Genet.
, vol.22
, pp. 5036-5047
-
-
Yu, C.E.1
-
121
-
-
0027480960
-
A novel gene containing a trinucleotide repeat that is expanded and unstable on Huntingtons disease chromosomes
-
MacDonald, M. E., et al. A novel gene containing a trinucleotide repeat that is expanded and unstable on Huntingtons disease chromosomes. Cell 72, 971-983 (1993).
-
(1993)
Cell
, vol.72
, pp. 971-983
-
-
MacDonald, M.E.1
-
122
-
-
17344363559
-
Length of huntingtin and its polyglutamine tract influences localization and frequency of intracellular aggregates
-
Martindale, D., et al. Length of huntingtin and its polyglutamine tract influences localization and frequency of intracellular aggregates. Nat. Genet. 18, 150-154 (1998).
-
(1998)
Nat. Genet.
, vol.18
, pp. 150-154
-
-
Martindale, D.1
-
123
-
-
30744470119
-
Abnormalities of neurogenesis in the R6/2 mouse model of Huntingtons disease are attributable to the in vivo microenvironment
-
Phillips, W., Morton, A. J. & Barker, R. A. Abnormalities of neurogenesis in the R6/2 mouse model of Huntingtons disease are attributable to the in vivo microenvironment. J. Neurosci. 25, 11564-11576 (2005).
-
(2005)
J. Neurosci.
, vol.25
, pp. 11564-11576
-
-
Phillips, W.1
Morton, A.J.2
Barker, R.A.3
-
124
-
-
1842608950
-
Decreased hippocampal cell proliferation in R6/1 Huntingtons mice
-
Lazic, S. E., et al. Decreased hippocampal cell proliferation in R6/1 Huntingtons mice. Neuroreport 15, 811-813 (2004).
-
(2004)
Neuroreport
, vol.15
, pp. 811-813
-
-
Lazic, S.E.1
-
125
-
-
77956494666
-
Impaired adult olfactory bulb neurogenesis in the R6/2 mouse model of Huntingtons disease
-
Kohl, Z., et al. Impaired adult olfactory bulb neurogenesis in the R6/2 mouse model of Huntingtons disease. BMC Neurosci. 11, 114 (2010).
-
(2010)
BMC Neurosci.
, vol.11
, pp. 114
-
-
Kohl, Z.1
-
126
-
-
84898894222
-
Whats wrong with epigenetics in Huntingtons disease?
-
Valor, L. M. & Guiretti, D. Whats wrong with epigenetics in Huntingtons disease? Neuropharmacology 80, 103-114 (2014).
-
(2014)
Neuropharmacology
, vol.80
, pp. 103-114
-
-
Valor, L.M.1
Guiretti, D.2
-
127
-
-
9744253732
-
Genome-wide demethylation destabilizes CTGCAG trinucleotide repeats in mammalian cells
-
Gorbunova, V., Seluanov, A., Mittelman, D. & Wilson, J. H. Genome-wide demethylation destabilizes CTGCAG trinucleotide repeats in mammalian cells. Hum. Mol. Genet. 13, 2979-2989 (2004).
-
(2004)
Hum. Mol. Genet.
, vol.13
, pp. 2979-2989
-
-
Gorbunova, V.1
Seluanov, A.2
Mittelman, D.3
Wilson, J.H.4
-
128
-
-
84861402086
-
Huntingtin protein interactions altered by polyglutamine expansion as determined by quantitative proteomic analysis
-
Ratovitski, T., et al. Huntingtin protein interactions altered by polyglutamine expansion as determined by quantitative proteomic analysis. Cell Cycle 11, 2006-2021 (2012).
-
(2012)
Cell Cycle
, vol.11
, pp. 2006-2021
-
-
Ratovitski, T.1
-
129
-
-
84863833900
-
Network organization of the huntingtin proteomic interactome in mammalian brain
-
Shirasaki, D. I., et al. Network organization of the huntingtin proteomic interactome in mammalian brain. Neuron 75, 41-57 (2012).
-
(2012)
Neuron
, vol.75
, pp. 41-57
-
-
Shirasaki, D.I.1
-
130
-
-
84873477433
-
Extensive changes in DNA methylation are associated with expression of mutant huntingtin
-
Ng, C. W., et al. Extensive changes in DNA methylation are associated with expression of mutant huntingtin. Proc. Natl Acad. Sci. USA 110, 2354-2359 (2013).
-
(2013)
Proc. Natl Acad. Sci. USA
, vol.110
, pp. 2354-2359
-
-
Ng, C.W.1
-
132
-
-
77649338801
-
Hippocampal neurogenesis as a target for the treatment of mental illness: A critical evaluation
-
DeCarolis, N. A. & Eisch, A. J. Hippocampal neurogenesis as a target for the treatment of mental illness: a critical evaluation. Neuropharmacology 58, 884-893 (2010).
-
(2010)
Neuropharmacology
, vol.58
, pp. 884-893
-
-
DeCarolis, N.A.1
Eisch, A.J.2
-
133
-
-
84872788760
-
Functional role of adult hippocampal neurogenesis as a therapeutic strategy for mental disorders
-
Jun, H., Mohammed Qasim Hussaini, S., Rigby, M. J. & Jang, M. H. Functional role of adult hippocampal neurogenesis as a therapeutic strategy for mental disorders. Neural Plast. 2012, 854285 (2012).
-
(2012)
Neural Plast.
, vol.2012
, pp. 854285
-
-
Jun, H.1
Mohammed Qasim Hussaini, S.2
Rigby, M.J.3
Jang, M.H.4
-
134
-
-
80054118405
-
The neurogenesis hypothesis of affective and anxiety disorders: Are we mistaking the scaffolding for the building?
-
Petrik, D., Lagace, D. C. & Eisch, A. J. The neurogenesis hypothesis of affective and anxiety disorders: are we mistaking the scaffolding for the building? Neuropharmacology 62, 21-34 (2012).
-
(2012)
Neuropharmacology
, vol.62
, pp. 21-34
-
-
Petrik, D.1
Lagace, D.C.2
Eisch, A.J.3
-
135
-
-
0042528720
-
Requirement of hippocampal neurogenesis for the behavioral effects of antidepressants
-
Santarelli, L., et al. Requirement of hippocampal neurogenesis for the behavioral effects of antidepressants. Science 301, 805-809 (2003).
-
(2003)
Science
, vol.301
, pp. 805-809
-
-
Santarelli, L.1
-
136
-
-
0034671366
-
Chronic antidepressant treatment increases neurogenesis in adult rat hippocampus
-
Malberg, J. E., Eisch, A. J., Nestler, E. J. & Duman, R. S. Chronic antidepressant treatment increases neurogenesis in adult rat hippocampus. J. Neurosci. 20, 9104-9110 (2000).
-
(2000)
J. Neurosci.
, vol.20
, pp. 9104-9110
-
-
Malberg, J.E.1
Eisch, A.J.2
Nestler, E.J.3
Duman, R.S.4
-
137
-
-
72949096531
-
Knockdown of brain-derived neurotrophic factor in specific brain sites precipitates behaviors associated with depression and reduces neurogenesis
-
Taliaz, D., Stall, N., Dar, D. E. & Zangen, A. Knockdown of brain-derived neurotrophic factor in specific brain sites precipitates behaviors associated with depression and reduces neurogenesis. Mol. Psychiatry 15, 80-92 (2010).
-
(2010)
Mol. Psychiatry
, vol.15
, pp. 80-92
-
-
Taliaz, D.1
Stall, N.2
Dar, D.E.3
Zangen, A.4
-
138
-
-
39749193120
-
MeCP2 deficiency in the brain decreases BDNF levels by REST/CoREST-mediated repression and increases TRKB production
-
Abuhatzira, L., Makedonski, K., Kaufman, Y., Razin, A. & Shemer, R. MeCP2 deficiency in the brain decreases BDNF levels by REST/CoREST-mediated repression and increases TRKB production. Epigenetics 2, 214-222 (2007).
-
(2007)
Epigenetics
, vol.2
, pp. 214-222
-
-
Abuhatzira, L.1
Makedonski, K.2
Kaufman, Y.3
Razin, A.4
Shemer, R.5
-
139
-
-
36448969801
-
Homeostatic regulation of MeCP2 expression by a CREB-induced microRNA
-
Klein, M. E., et al. Homeostatic regulation of MeCP2 expression by a CREB-induced microRNA. Nat. Neurosci. 10, 1513-1514 (2007).
-
(2007)
Nat. Neurosci.
, vol.10
, pp. 1513-1514
-
-
Klein, M.E.1
-
140
-
-
64449086698
-
Bdnf overexpression in hippocampal neurons prevents dendritic atrophy caused by Rett-associated MECP2 mutations
-
Larimore, J. L., et al. Bdnf overexpression in hippocampal neurons prevents dendritic atrophy caused by Rett-associated MECP2 mutations. Neurobiol. Dis. 34, 199-211 (2009).
-
(2009)
Neurobiol. Dis.
, vol.34
, pp. 199-211
-
-
Larimore, J.L.1
-
141
-
-
84890441953
-
BDNF deregulation in Rett syndrome
-
Li, W. & Pozzo-Miller, L. BDNF deregulation in Rett syndrome. Neuropharmacology 76, 737-746 (2014).
-
(2014)
Neuropharmacology
, vol.76
, pp. 737-746
-
-
Li, W.1
Pozzo-Miller, L.2
-
142
-
-
84942035052
-
Rett syndrome: Disruption of epigenetic control of postnatal neurological functions
-
Pohodich, A. E. & Zoghbi, H. Y. Rett syndrome: disruption of epigenetic control of postnatal neurological functions. Hum. Mol. Genet. 24, R10-R16 (2015).
-
(2015)
Hum. Mol. Genet.
, vol.24
, pp. R10-R16
-
-
Pohodich, A.E.1
Zoghbi, H.Y.2
-
143
-
-
33749590330
-
Brain-specific phosphorylation of MeCP2 regulates activity-dependent Bdnf transcription, dendritic growth, and spine maturation
-
Zhou, Z., et al. Brain-specific phosphorylation of MeCP2 regulates activity-dependent Bdnf transcription, dendritic growth, and spine maturation. Neuron 52, 255-269 (2006).
-
(2006)
Neuron
, vol.52
, pp. 255-269
-
-
Zhou, Z.1
-
144
-
-
84922341615
-
Cell cycle-linked MeCP2 phosphorylation modulates adult neurogenesis involving the Notch signalling pathway
-
Li, H., et al. Cell cycle-linked MeCP2 phosphorylation modulates adult neurogenesis involving the Notch signalling pathway. Nat. Commun. 5, 5601 (2014).
-
(2014)
Nat. Commun.
, vol.5
, pp. 5601
-
-
Li, H.1
-
145
-
-
33750996712
-
Social brain dysfunctions in schizophrenia: A review of neuroimaging studies
-
Brunet-Gouet, E. & Decety, J. Social brain dysfunctions in schizophrenia: a review of neuroimaging studies. Psychiatry Res. 148, 75-92 (2006).
-
(2006)
Psychiatry Res.
, vol.148
, pp. 75-92
-
-
Brunet-Gouet, E.1
Decety, J.2
-
146
-
-
33646377899
-
Neural stem cell proliferation is decreased in schizophrenia, but not in depression
-
Reif, A., et al. Neural stem cell proliferation is decreased in schizophrenia, but not in depression. Mol. Psychiatry 11, 514-522 (2006).
-
(2006)
Mol. Psychiatry
, vol.11
, pp. 514-522
-
-
Reif, A.1
-
147
-
-
84911397798
-
Epigenetic mechanisms in schizophrenia
-
Akbarian, S. Epigenetic mechanisms in schizophrenia. Dialogues Clin. Neurosci. 16, 405-417 (2014).
-
(2014)
Dialogues Clin. Neurosci.
, vol.16
, pp. 405-417
-
-
Akbarian, S.1
-
148
-
-
84880867623
-
DNA methylation of the BDNF gene and its relevance to psychiatric disorders
-
Ikegame, T., et al. DNA methylation of the BDNF gene and its relevance to psychiatric disorders. J. Hum. Genet. 58, 434-438 (2013).
-
(2013)
J. Hum. Genet.
, vol.58
, pp. 434-438
-
-
Ikegame, T.1
-
149
-
-
84884131438
-
DNA-methylation gene network dysregulation in peripheral blood lymphocytes of schizophrenia patients
-
Auta, J., et al. DNA-methylation gene network dysregulation in peripheral blood lymphocytes of schizophrenia patients. Schizophr Res. 150, 312-318 (2013).
-
(2013)
Schizophr Res.
, vol.150
, pp. 312-318
-
-
Auta, J.1
-
150
-
-
67349238734
-
Histone deacetylase inhibitors and candidate gene expression: An in vivo and in vitro approach to studying chromatin remodeling in a clinical population
-
Gavin, D. P., Kartan, S., Chase, K., Jayaraman, S. & Sharma, R. P. Histone deacetylase inhibitors and candidate gene expression: an in vivo and in vitro approach to studying chromatin remodeling in a clinical population. J. Psychiatr. Res. 43, 870-876 (2009).
-
(2009)
J. Psychiatr. Res.
, vol.43
, pp. 870-876
-
-
Gavin, D.P.1
Kartan, S.2
Chase, K.3
Jayaraman, S.4
Sharma, R.P.5
-
151
-
-
84896732939
-
Methylome-wide association study of schizophrenia: Identifying blood biomarker signatures of environmental insults
-
Aberg, K. A., et al. Methylome-wide association study of schizophrenia: identifying blood biomarker signatures of environmental insults. JAMA Psychiatry 71, 255-264 (2014).
-
(2014)
JAMA Psychiatry
, vol.71
, pp. 255-264
-
-
Aberg, K.A.1
-
152
-
-
84953729873
-
Methylation QTLs in the developing brain and their enrichment in schizophrenia risk loci
-
Hannon, E., et al. Methylation QTLs in the developing brain and their enrichment in schizophrenia risk loci. Nat. Neurosci. 19, 48-54 (2016).
-
(2016)
Nat. Neurosci.
, vol.19
, pp. 48-54
-
-
Hannon, E.1
-
153
-
-
84953762043
-
Mapping DNA methylation across development, genotype and schizophrenia in the human frontal cortex
-
Jaffe, A. E., et al. Mapping DNA methylation across development, genotype and schizophrenia in the human frontal cortex. Nat. Neurosci. 19, 40-47 (2016).
-
(2016)
Nat. Neurosci.
, vol.19
, pp. 40-47
-
-
Jaffe, A.E.1
-
154
-
-
77951499826
-
Roles of small regulatory RNAs in determining neuronal identity
-
Li, X. & Jin, P. Roles of small regulatory RNAs in determining neuronal identity. Nat. Rev. Neurosci. 11, 329-338 (2010).
-
(2010)
Nat. Rev. Neurosci.
, vol.11
, pp. 329-338
-
-
Li, X.1
Jin, P.2
-
155
-
-
84906281802
-
Long non-coding RNAdependent transcriptional regulation in neuronal development and disease
-
Clark, B. S. & Blackshaw, S. Long non-coding RNAdependent transcriptional regulation in neuronal development and disease. Front. Genet. 5, 164 (2014).
-
(2014)
Front. Genet.
, vol.5
, pp. 164
-
-
Clark, B.S.1
Blackshaw, S.2
-
156
-
-
84885400003
-
Chromatin-based epigenetics of adult subventricular zone neural stem cells
-
Gonzales-Roybal, G. & Lim, D. A. Chromatin-based epigenetics of adult subventricular zone neural stem cells. Front. Genet. 4, 194 (2013).
-
(2013)
Front. Genet.
, vol.4
, pp. 194
-
-
Gonzales-Roybal, G.1
Lim, D.A.2
-
157
-
-
84872847340
-
Reversible RNA adenosine methylation in biological regulation
-
Jia, G., Fu, Y. & He, C. Reversible RNA adenosine methylation in biological regulation. Trends Genet. 29, 108-115 (2013).
-
(2013)
Trends Genet.
, vol.29
, pp. 108-115
-
-
Jia, G.1
Fu, Y.2
He, C.3
-
158
-
-
84937002114
-
RNA N6-methyladenosine methylation in post-transcriptional gene expression regulation
-
Yue, Y., Liu, J. & He, C. RNA N6-methyladenosine methylation in post-transcriptional gene expression regulation. Genes Dev. 29, 1343-1355 (2015).
-
(2015)
Genes Dev.
, vol.29
, pp. 1343-1355
-
-
Yue, Y.1
Liu, J.2
He, C.3
-
159
-
-
84860162767
-
Pten deletion in adult hippocampal neural stem/progenitor cells causes cellular abnormalities and alters neurogenesis
-
Amiri, A., et al. Pten deletion in adult hippocampal neural stem/progenitor cells causes cellular abnormalities and alters neurogenesis. J. Neurosci. 32, 5880-5890 (2012).
-
(2012)
J. Neurosci.
, vol.32
, pp. 5880-5890
-
-
Amiri, A.1
-
160
-
-
84878616759
-
MicroRNA cluster miR-17-92 regulates neural stem cell expansion and transition to intermediate progenitors in the developing mouse neocortex
-
Bian, S., et al. MicroRNA cluster miR-17-92 regulates neural stem cell expansion and transition to intermediate progenitors in the developing mouse neocortex. Cell Rep. 3, 1398-1406 (2013).
-
(2013)
Cell Rep.
, vol.3
, pp. 1398-1406
-
-
Bian, S.1
-
161
-
-
84860284308
-
MicroRNA-9 regulates axon extension and branching by targeting Map1b in mouse cortical neurons
-
Dajas-Bailador, F., et al. microRNA-9 regulates axon extension and branching by targeting Map1b in mouse cortical neurons. Nat. Neurosci. 15, 697-699 (2012).
-
(2012)
Nat. Neurosci.
, vol.15
, pp. 697-699
-
-
Dajas-Bailador, F.1
-
162
-
-
64049095014
-
A feedback regulatory loop involving microRNA-9 and nuclear receptor TLX in neural stem cell fate determination
-
Zhao, C., Sun, G., Li, S. & Shi, Y. A feedback regulatory loop involving microRNA-9 and nuclear receptor TLX in neural stem cell fate determination. Nat. Struct. Mol. Biol. 16, 365-371 (2009).
-
(2009)
Nat. Struct. Mol. Biol.
, vol.16
, pp. 365-371
-
-
Zhao, C.1
Sun, G.2
Li, S.3
Shi, Y.4
-
163
-
-
82555196537
-
MiR-137 forms a regulatory loop with nuclear receptor TLX and LSD1 in neural stem cells
-
Sun, G., et al. miR-137 forms a regulatory loop with nuclear receptor TLX and LSD1 in neural stem cells. Nat. Commun. 2, 529 (2011).
-
(2011)
Nat. Commun.
, vol.2
, pp. 529
-
-
Sun, G.1
-
164
-
-
76649088031
-
MicroRNA let-7b regulates neural stem cell proliferation and differentiation by targeting nuclear receptor TLX signaling
-
Zhao, C., et al. MicroRNA let-7b regulates neural stem cell proliferation and differentiation by targeting nuclear receptor TLX signaling. Proc. Natl Acad. Sci. USA 107, 1876-1881 (2010).
-
(2010)
Proc. Natl Acad. Sci. USA
, vol.107
, pp. 1876-1881
-
-
Zhao, C.1
-
165
-
-
77956099873
-
Epigenetic regulation of miR-184 by MBD1 governs neural stem cell proliferation and differentiation
-
Liu, C., et al. Epigenetic regulation of miR-184 by MBD1 governs neural stem cell proliferation and differentiation. Cell Stem Cell 6, 433-444 (2010).
-
(2010)
Cell Stem Cell
, vol.6
, pp. 433-444
-
-
Liu, C.1
-
166
-
-
63649138643
-
MiR-124 regulates adult neurogenesis in the subventricular zone stem cell niche
-
Cheng, L. C., Pastrana, E., Tavazoie, M. & Doetsch, F. miR-124 regulates adult neurogenesis in the subventricular zone stem cell niche. Nat. Neurosci. 12, 399-408 (2009).
-
(2009)
Nat. Neurosci.
, vol.12
, pp. 399-408
-
-
Cheng, L.C.1
Pastrana, E.2
Tavazoie, M.3
Doetsch, F.4
-
167
-
-
84902141800
-
Long noncoding RNAs in cell-fate programming and reprogramming
-
Flynn, R. A. & Chang, H. Y. Long noncoding RNAs in cell-fate programming and reprogramming. Cell Stem Cell 14, 752-761 (2014).
-
(2014)
Cell Stem Cell
, vol.14
, pp. 752-761
-
-
Flynn, R.A.1
Chang, H.Y.2
-
168
-
-
68149182666
-
Balanced gene regulation by an embryonic brain ncRNA is critical for adult hippocampal GABA circuitry
-
Bond, A. M., et al. Balanced gene regulation by an embryonic brain ncRNA is critical for adult hippocampal GABA circuitry. Nat. Neurosci. 12, 1020-1027 (2009).
-
(2009)
Nat. Neurosci.
, vol.12
, pp. 1020-1027
-
-
Bond, A.M.1
-
169
-
-
84877575447
-
Integration of genome-wide approaches identifies lncRNAs of adult neural stem cells and their progeny in vivo
-
Ramos, A. D., et al. Integration of genome-wide approaches identifies lncRNAs of adult neural stem cells and their progeny in vivo. Cell Stem Cell 12, 616-628 (2013).
-
(2013)
Cell Stem Cell
, vol.12
, pp. 616-628
-
-
Ramos, A.D.1
-
170
-
-
84899586607
-
The dynamic epitranscriptome: N6-methyladenosine and gene expression control
-
Meyer, K. D. & Jaffrey, S. R. The dynamic epitranscriptome: N6-methyladenosine and gene expression control. Nat. Rev. Mol. Cell Biol. 15, 313-326 (2014).
-
(2014)
Nat. Rev. Mol. Cell Biol.
, vol.15
, pp. 313-326
-
-
Meyer, K.D.1
Jaffrey, S.R.2
-
171
-
-
84919457819
-
M6A RNA modification controls cell fate transition in mammalian embryonic stem cells
-
Batista, P. J., et al. m6A RNA modification controls cell fate transition in mammalian embryonic stem cells. Cell Stem Cell 15, 707-719 (2014).
-
(2014)
Cell Stem Cell
, vol.15
, pp. 707-719
-
-
Batista, P.J.1
-
172
-
-
84922342926
-
M6A mRNA methylation facilitates resolution of nave pluripotency toward differentiation
-
Geula, S., et al. m6A mRNA methylation facilitates resolution of nave pluripotency toward differentiation. Science 347, 1002-1006 (2015).
-
(2015)
Science
, vol.347
, pp. 1002-1006
-
-
Geula, S.1
-
173
-
-
0030712151
-
Purification and cDNA cloning of the AdoMet-binding subunit of the human mRNA (N6-adenosine)-methyltransferase
-
Bokar, J. A., Shambaugh, M. E., Polayes, D., Matera, A. G. & Rottman, F. M. Purification and cDNA cloning of the AdoMet-binding subunit of the human mRNA (N6-adenosine)-methyltransferase. RNA 3, 1233-1247 (1997).
-
(1997)
RNA
, vol.3
, pp. 1233-1247
-
-
Bokar, J.A.1
Shambaugh, M.E.2
Polayes, D.3
Matera, A.G.4
Rottman, F.M.5
-
174
-
-
0028242885
-
Characterization and partial purification of mRNA N6-adenosine methyltransferase from HeLa cell nuclei. Internal mRNA methylation requires a multisubunit complex
-
Bokar, J. A., Rath-Shambaugh, M. E., Ludwiczak, R., Narayan, P. & Rottman, F. Characterization and partial purification of mRNA N6-adenosine methyltransferase from HeLa cell nuclei. Internal mRNA methylation requires a multisubunit complex. J. Biol. Chem. 269, 17697-17704 (1994).
-
(1994)
J. Biol. Chem.
, vol.269
, pp. 17697-17704
-
-
Bokar, J.A.1
Rath-Shambaugh, M.E.2
Ludwiczak, R.3
Narayan, P.4
Rottman, F.5
-
175
-
-
84897110592
-
A METTL3-METTL14 complex mediates mammalian nuclear RNA N6-adenosine methylation
-
Liu, J., et al. A METTL3-METTL14 complex mediates mammalian nuclear RNA N6-adenosine methylation. Nat. Chem. Biol. 10, 93-95 (2014).
-
(2014)
Nat. Chem. Biol.
, vol.10
, pp. 93-95
-
-
Liu, J.1
-
176
-
-
84893746230
-
Mammalian WTAP is a regulatory subunit of the RNA N6-methyladenosine methyltransferase
-
Ping, X.-L., et al. Mammalian WTAP is a regulatory subunit of the RNA N6-methyladenosine methyltransferase. Cell Res. 24, 177-189 (2014).
-
(2014)
Cell Res.
, vol.24
, pp. 177-189
-
-
Ping, X.-L.1
-
177
-
-
84893310526
-
N6-methyladenosine modification destabilizes developmental regulators in embryonic stem cells
-
Wang, Y., et al. N6-methyladenosine modification destabilizes developmental regulators in embryonic stem cells. Nat. Cell Biol. 16, 191-198 (2014).
-
(2014)
Nat. Cell Biol.
, vol.16
, pp. 191-198
-
-
Wang, Y.1
-
178
-
-
81355146483
-
N6-methyladenosine in nuclear RNA is a major substrate of the obesity-associated FTO
-
Jia, G., et al. N6-methyladenosine in nuclear RNA is a major substrate of the obesity-associated FTO. Nat. Chem. Biol. 7, 885-887 (2011).
-
(2011)
Nat. Chem. Biol.
, vol.7
, pp. 885-887
-
-
Jia, G.1
-
179
-
-
84872274463
-
ALKBH5 is a mammalian RNA demethylase that impacts RNA metabolism and mouse fertility
-
Zheng, G., et al. ALKBH5 is a mammalian RNA demethylase that impacts RNA metabolism and mouse fertility. Mol. Cell 49, 18-29 (2013).
-
(2013)
Mol. Cell
, vol.49
, pp. 18-29
-
-
Zheng, G.1
-
180
-
-
84892372347
-
N6-methyladenosine-dependent regulation of messenger RNA stability
-
Wang, X., et al. N6-methyladenosine-dependent regulation of messenger RNA stability. Nature 505, 117-120 (2014).
-
(2014)
Nature
, vol.505
, pp. 117-120
-
-
Wang, X.1
-
181
-
-
84924072927
-
N6-methyladenosine-dependent RNA structural switches regulate RNA-protein interactions
-
Liu, N., et al. N6-methyladenosine-dependent RNA structural switches regulate RNA-protein interactions. Nature 518, 560-564 (2015).
-
(2015)
Nature
, vol.518
, pp. 560-564
-
-
Liu, N.1
-
182
-
-
84941424170
-
HNRNPA2B1 is a mediator of m6A-dependent nuclear RNA processing events
-
Alarcon, C. R., et al. HNRNPA2B1 is a mediator of m6A-dependent nuclear RNA processing events. Cell 162, 1299-1308 (2015).
-
(2015)
Cell
, vol.162
, pp. 1299-1308
-
-
Alarcon, C.R.1
-
183
-
-
84945288814
-
Dynamic m6A mRNA methylation directs translational control of heat shock response
-
Zhou, J., et al. Dynamic m6A mRNA methylation directs translational control of heat shock response. Nature 526, 591-594 (2015).
-
(2015)
Nature
, vol.526
, pp. 591-594
-
-
Zhou, J.1
|