Extensive changes in DNA methylation are associated with expression of mutant huntingtin

Proceedings of the National Academy of Sciences of the United States of America

Volumn 110, Issue 6, 2013, Pages 2354-2359

  Ng, Christopher W ^a   Yildirim, Ferah ^a   Yap, Yoon Sing ^a   Dalin, Simona ^a   Matthews, Bryan J ^a   Velez, Patricio J ^a   Labadorf, Adam ^a   Housman, David E ^b   Fraenkel, Ernest ^a  

^a Departments of Biological Engineering   (United States)

^b MASSACHUSETTS INSTITUTE OF TECHNOLOGY   (United States)

Author keywords

Epigenomics; MRNA Seq; Transcription

Indexed keywords

BISULFITE; HUNTINGTIN; POLYGLUTAMINE; TRANSCRIPTION FACTOR AP 1; TRANSCRIPTION FACTOR SOX2;

ARTICLE; CELL DEATH; CELL MIGRATION; CELL PROLIFERATION; CHROMATIN IMMUNOPRECIPITATION; COGNITIVE DEFECT; CPG ISLAND; DNA METHYLATION; GENE EXPRESSION; GENE MUTATION; HUNTINGTON CHOREA; NERVE CELL; NERVOUS SYSTEM DEVELOPMENT; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; REGULATORY MECHANISM; SIGNAL TRANSDUCTION;

ANIMALS; CELL LINE; CHROMATIN IMMUNOPRECIPITATION; CPG ISLANDS; DISEASE MODELS, ANIMAL; DNA METHYLATION; GENE EXPRESSION; HUMANS; HUNTINGTON DISEASE; MICE; MUTANT PROTEINS; NERVE TISSUE PROTEINS; NUCLEAR PROTEINS; SOXB1 TRANSCRIPTION FACTORS; TRANSCRIPTION FACTOR AP-1;

EID: 84873477433     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1221292110     Document Type: Article

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