-
1
-
-
0032830639
-
Rett syndrome is caused by mutations in X-linked MECP2, encoding methyl-CpG-binding protein 2
-
Amir RE, et al. (1999) Rett syndrome is caused by mutations in X-linked MECP2, encoding methyl-CpG-binding protein 2. Nat Genet 23(2):185-188.
-
(1999)
Nat Genet
, vol.23
, Issue.2
, pp. 185-188
-
-
Amir, R.E.1
-
2
-
-
84928207237
-
Rett syndrome: A complex disorder with simple roots
-
Lyst MJ, Bird A (2015) Rett syndrome: A complex disorder with simple roots. Nat Rev Genet, 10.1038/nrg3897.
-
(2015)
Nat Rev Genet
-
-
Lyst, M.J.1
Bird, A.2
-
3
-
-
0035094767
-
A mouse Mecp2-null mutation causes neurological symptoms that mimic Rett syndrome
-
Guy J, Hendrich B, Holmes M, Martin JE, Bird A (2001) A mouse Mecp2-null mutation causes neurological symptoms that mimic Rett syndrome. Nat Genet 27(3):322-326.
-
(2001)
Nat Genet
, vol.27
, Issue.3
, pp. 322-326
-
-
Guy, J.1
Hendrich, B.2
Holmes, M.3
Martin, J.E.4
Bird, A.5
-
4
-
-
8444253290
-
Mild overexpression of MeCP2 causes a progressive neurological disorder in mice
-
Collins AL, et al. (2004) Mild overexpression of MeCP2 causes a progressive neurological disorder in mice. Hum Mol Genet 13(21):2679-2689.
-
(2004)
Hum Mol Genet
, vol.13
, Issue.21
, pp. 2679-2689
-
-
Collins, A.L.1
-
5
-
-
45849105557
-
MeCP2, a key contributor to neurological disease, activates and represses transcription
-
Chahrour M, et al. (2008) MeCP2, a key contributor to neurological disease, activates and represses transcription. Science 320(5880):1224-1229.
-
(2008)
Science
, vol.320
, Issue.5880
, pp. 1224-1229
-
-
Chahrour, M.1
-
6
-
-
23944503759
-
Duplication of the MECP2 region is a frequent cause of severe mental retardation and progressive neurological symptoms in males
-
Van Esch H, et al. (2005) Duplication of the MECP2 region is a frequent cause of severe mental retardation and progressive neurological symptoms in males. Am J Hum Genet 77(3):442-453.
-
(2005)
Am J Hum Genet
, vol.77
, Issue.3
, pp. 442-453
-
-
Van Esch, H.1
-
7
-
-
33749081269
-
Increased MECP2 gene copy number as the result of genomic duplication in neurodevelopmentally delayed males
-
del Gaudio D, et al. (2006) Increased MECP2 gene copy number as the result of genomic duplication in neurodevelopmentally delayed males. Genet Med 8(12):784-792.
-
(2006)
Genet Med
, vol.8
, Issue.12
, pp. 784-792
-
-
Del Gaudio, D.1
-
8
-
-
0026747761
-
Purification, sequence, and cellular localization of a novel chromosomal protein that binds to methylated DNA
-
Lewis JD, et al. (1992) Purification, sequence, and cellular localization of a novel chromosomal protein that binds to methylated DNA. Cell 69(6):905-914.
-
(1992)
Cell
, vol.69
, Issue.6
, pp. 905-914
-
-
Lewis, J.D.1
-
9
-
-
0029655782
-
DNA methylation specifies chromosomal localization of MeCP2
-
Nan X, Tate P, Li E, Bird A (1996) DNA methylation specifies chromosomal localization of MeCP2. Mol Cell Biol 16(1):414-421.
-
(1996)
Mol Cell Biol
, vol.16
, Issue.1
, pp. 414-421
-
-
Nan, X.1
Tate, P.2
Li, E.3
Bird, A.4
-
10
-
-
0031837109
-
Methylated DNA and MeCP2 recruit histone deacetylase to repress transcription
-
Jones PL, et al. (1998) Methylated DNA and MeCP2 recruit histone deacetylase to repress transcription. Nat Genet 19(2):187-191.
-
(1998)
Nat Genet
, vol.19
, Issue.2
, pp. 187-191
-
-
Jones, P.L.1
-
11
-
-
76849094693
-
Neuronal MeCP2 is expressed at near histone-octamer levels and globally alters the chromatin state
-
Skene PJ, et al. (2010) Neuronal MeCP2 is expressed at near histone-octamer levels and globally alters the chromatin state. Mol Cell 37(4):457-468.
-
(2010)
Mol Cell
, vol.37
, Issue.4
, pp. 457-468
-
-
Skene, P.J.1
-
12
-
-
34447536953
-
Intrinsic disorder and autonomous domain function in the multifunctional nuclear protein, MeCP2
-
Adams VH, McBryant SJ, Wade PA, Woodcock CL, Hansen JC (2007) Intrinsic disorder and autonomous domain function in the multifunctional nuclear protein, MeCP2. J Biol Chem 282(20):15057-15064.
-
(2007)
J Biol Chem
, vol.282
, Issue.20
, pp. 15057-15064
-
-
Adams, V.H.1
McBryant, S.J.2
Wade, P.A.3
Woodcock, C.L.4
Hansen, J.C.5
-
13
-
-
84874759852
-
An AT-hook domain in MeCP2 determines the clinical course of Rett syndrome and related disorders
-
Baker SA, et al. (2013) An AT-hook domain in MeCP2 determines the clinical course of Rett syndrome and related disorders. Cell 152(5):984-996.
-
(2013)
Cell
, vol.152
, Issue.5
, pp. 984-996
-
-
Baker, S.A.1
-
14
-
-
84871563384
-
MeCP2 binds to 5hmC enriched within active genes and accessible chromatin in the nervous system
-
Mellén M, Ayata P, Dewell S, Kriaucionis S, Heintz N (2012) MeCP2 binds to 5hmC enriched within active genes and accessible chromatin in the nervous system. Cell 151(7):1417-1430.
-
(2012)
Cell
, vol.151
, Issue.7
, pp. 1417-1430
-
-
Mellén, M.1
Ayata, P.2
Dewell, S.3
Kriaucionis, S.4
Heintz, N.5
-
15
-
-
84893740377
-
Distribution, recognition and regulation of non-CpG methylation in the adult mammalian brain
-
Guo JU, et al. (2014) Distribution, recognition and regulation of non-CpG methylation in the adult mammalian brain. Nat Neurosci 17(2):215-222.
-
(2014)
Nat Neurosci
, vol.17
, Issue.2
, pp. 215-222
-
-
Guo, J.U.1
-
16
-
-
84876278080
-
Methylation-dependent and -independent genomic targeting principles of the MBD protein family
-
Baubec T, Ivánek R, Lienert F, Schübeler D (2013) Methylation-dependent and -independent genomic targeting principles of the MBD protein family. Cell 153(2):480-492.
-
(2013)
Cell
, vol.153
, Issue.2
, pp. 480-492
-
-
Baubec, T.1
Ivánek, R.2
Lienert, F.3
Schübeler, D.4
-
17
-
-
0037081840
-
Insight into Rett syndrome: MeCP2 levels display tissue- and cell-specific differences and correlate with neuronal maturation
-
Shahbazian MD, Antalffy B, Armstrong DL, Zoghbi HY (2002) Insight into Rett syndrome: MeCP2 levels display tissue- and cell-specific differences and correlate with neuronal maturation. Hum Mol Genet 11(2):115-124.
-
(2002)
Hum Mol Genet
, vol.11
, Issue.2
, pp. 115-124
-
-
Shahbazian, M.D.1
Antalffy, B.2
Armstrong, D.L.3
Zoghbi, H.Y.4
-
18
-
-
84904976180
-
Rett-causing mutations reveal two domains critical for MeCP2 function and for toxicity in MECP2 duplication syndrome mice
-
Heckman LD, Chahrour MH, Zoghbi HY (2014) Rett-causing mutations reveal two domains critical for MeCP2 function and for toxicity in MECP2 duplication syndrome mice. eLife 3:02676.
-
(2014)
eLife
, vol.3
, pp. 02676
-
-
Heckman, L.D.1
Chahrour, M.H.2
Zoghbi, H.Y.3
-
19
-
-
84879663784
-
Global epigenomic reconfiguration during mammalian brain development
-
Lister R, et al. (2013) Global epigenomic reconfiguration during mammalian brain development. Science 341(6146):1237905.
-
(2013)
Science
, vol.341
, Issue.6146
, pp. 1237905
-
-
Lister, R.1
-
20
-
-
1542563409
-
Initial sequencing and comparative analysis of the mouse genome
-
Waterston RH, et al.; Mouse Genome Sequencing Consortium (2002) Initial sequencing and comparative analysis of the mouse genome. Nature 420(6915):520-562.
-
(2002)
Nature
, vol.420
, Issue.6915
, pp. 520-562
-
-
Waterston, R.H.1
-
21
-
-
77954659099
-
Relationship between nucleosome positioning and DNA methylation
-
Chodavarapu RK, et al. (2010) Relationship between nucleosome positioning and DNA methylation. Nature 466(7304):388-392.
-
(2010)
Nature
, vol.466
, Issue.7304
, pp. 388-392
-
-
Chodavarapu, R.K.1
-
22
-
-
77958481159
-
Nucleosome-interacting proteins regulated by DNA and histone methylation
-
Bartke T, et al. (2010) Nucleosome-interacting proteins regulated by DNA and histone methylation. Cell 143(3):470-484.
-
(2010)
Cell
, vol.143
, Issue.3
, pp. 470-484
-
-
Bartke, T.1
-
23
-
-
43749098985
-
DNA methylation landscapes: Provocative insights from epigenomics
-
Suzuki MM, Bird A (2008) DNA methylation landscapes: Provocative insights from epigenomics. Nat Rev Genet 9(6):465-476.
-
(2008)
Nat Rev Genet
, vol.9
, Issue.6
, pp. 465-476
-
-
Suzuki, M.M.1
Bird, A.2
-
24
-
-
34250188803
-
Genomic patterns of DNA methylation: Targets and function of an epigenetic mark
-
Weber M, Schübeler D (2007) Genomic patterns of DNA methylation: Targets and function of an epigenetic mark. Curr Opin Cell Biol 19(3):273-280.
-
(2007)
Curr Opin Cell Biol
, vol.19
, Issue.3
, pp. 273-280
-
-
Weber, M.1
Schübeler, D.2
-
25
-
-
31444434393
-
The disease progression of Mecp2 mutant mice is affected by the level of BDNF expression
-
Chang Q, Khare G, Dani V, Nelson S, Jaenisch R (2006) The disease progression of Mecp2 mutant mice is affected by the level of BDNF expression. Neuron 49(3):341-348.
-
(2006)
Neuron
, vol.49
, Issue.3
, pp. 341-348
-
-
Chang, Q.1
Khare, G.2
Dani, V.3
Nelson, S.4
Jaenisch, R.5
-
26
-
-
84928533445
-
Disruption of DNA-methylation-dependent long gene repression in Rett syndrome
-
Gabel HW, et al. (2015) Disruption of DNA-methylation-dependent long gene repression in Rett syndrome. Nature 10.1038/nature14319.
-
(2015)
Nature
-
-
Gabel, H.W.1
-
27
-
-
34250643467
-
Ablation of de novo DNA methyltransferase Dnmt3a in the nervous system leads to neuromuscular defects and shortened lifespan
-
Nguyen S, Meletis K, Fu D, Jhaveri S, Jaenisch R (2007) Ablation of de novo DNA methyltransferase Dnmt3a in the nervous system leads to neuromuscular defects and shortened lifespan. Dev Dyn 236(6):1663-1676.
-
(2007)
Dev Dyn
, vol.236
, Issue.6
, pp. 1663-1676
-
-
Nguyen, S.1
Meletis, K.2
Fu, D.3
Jhaveri, S.4
Jaenisch, R.5
-
28
-
-
29244449333
-
Histone H1 depletion in mammals alters global chromatin structure but causes specific changes in gene regulation
-
Fan Y, et al. (2005) Histone H1 depletion in mammals alters global chromatin structure but causes specific changes in gene regulation. Cell 123(7):1199-1212.
-
(2005)
Cell
, vol.123
, Issue.7
, pp. 1199-1212
-
-
Fan, Y.1
-
29
-
-
33847266846
-
Reversal of neurological defects in a mouse model of Rett syndrome
-
Guy J, Gan J, Selfridge J, Cobb S, Bird A (2007) Reversal of neurological defects in a mouse model of Rett syndrome. Science 315(5815):1143-1147.
-
(2007)
Science
, vol.315
, Issue.5815
, pp. 1143-1147
-
-
Guy, J.1
Gan, J.2
Selfridge, J.3
Cobb, S.4
Bird, A.5
-
30
-
-
79960075356
-
Adult neural function requires MeCP2
-
McGraw CM, Samaco RC, Zoghbi HY (2011) Adult neural function requires MeCP2. Science 333(6039):186.
-
(2011)
Science
, vol.333
, Issue.6039
, pp. 186
-
-
McGraw, C.M.1
Samaco, R.C.2
Zoghbi, H.Y.3
|