LRRK2 overexpression alters glutamatergic presynaptic plasticity, striatal dopamine tone, postsynaptic signal transduction, motor activity and memory

Human Molecular Genetics

Volumn 24, Issue 5, 2015, Pages 1336-1349

  Beccano Kelly, Dayne A ^a,c   Volta, Mattia ^a,c   A Munsie, Lise N ^a,c   Paschall, Sarah A ^a,c   Tatarnikov, Igor ^a,c   Co, Kimberley ^a,c   Chou, Patrick ^a,c   Cao, Li Ping ^a,c   Bergeron, Sabrina ^a,c   Mitchell, Emma ^a,c   Han, Heather ^a,c   Melrose, Heather L ^d   Tapia, Lucia ^a,c   Raymond, Lynn A ^a,c   A Farrer, Matthew J ^a,c   Milnerwood, Austen J ^a,b,c  

^a UNIVERSITY OF BRITISH COLUMBIA   (Canada)

^b UNIVERSITY OF BRITISH COLUMBIA   (Canada)

^c UNIVERSITY OF BRITISH COLUMBIA   (Canada)

^d MAYO GRADUATE SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DOPAMINE; DOPAMINE RECEPTOR; GLUTAMIC ACID; LEUCINE RICH REPEAT KINASE 2; PHOSPHOPROTEIN DARPP 32; DOPAMINE 2 RECEPTOR; GLUTAMIC ACID DERIVATIVE; LRRK2 PROTEIN, MOUSE; PHOSPHOPROTEIN; PROTEIN SERINE THREONINE KINASE;

ADULT; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; CORPUS STRIATUM; MALE; MEMORY; MOTOR ACTIVITY; MOUSE; NERVE CELL; NERVE CELL PLASTICITY; NEUROMODULATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; STRIATAL PROJECTION NEURON; SYNAPTIC TRANSMISSION; ANIMAL; GENETICS; METABOLISM; NEOSTRIATUM; PARKINSON DISEASE; TRANSGENIC MOUSE;

ANIMALIA; MUS;

ANIMALS; DOPAMINE; GLUTAMATES; MALE; MEMORY; MICE; MICE, TRANSGENIC; MOTOR ACTIVITY; NEOSTRIATUM; NEURONAL PLASTICITY; NEURONS; PARKINSON DISEASE; PHOSPHOPROTEINS; PROTEIN-SERINE-THREONINE KINASES; RECEPTORS, DOPAMINE D2; SIGNAL TRANSDUCTION; SYNAPTIC TRANSMISSION;

EID: 84924455094     PISSN: 09646906     EISSN: 14602083     Source Type: Journal    
DOI: 10.1093/hmg/ddu543     Document Type: Article

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