-
2
-
-
84857056404
-
Life expectancy and cardiovascular mortality in persons with schizophrenia
-
Laursen TM, Munk-Olsen T, Vestergaard M. Life expectancy and cardiovascular mortality in persons with schizophrenia. Curr Opin Psychiatry. 2012;25:83-88.
-
(2012)
Curr Opin Psychiatry.
, vol.25
, pp. 83-88
-
-
Laursen, T.M.1
Munk-Olsen, T.2
Vestergaard, M.3
-
3
-
-
34948840329
-
A systematic review of mortality in schizophrenia: is the differential mortality gap worsening over time?
-
Saha S, Chant D, McGrath J. A systematic review of mortality in schizophrenia: is the differential mortality gap worsening over time? Arch Gen Psychiatry. 2007;64:1123-1131.
-
(2007)
Arch Gen Psychiatry.
, vol.64
, pp. 1123-1131
-
-
Saha, S.1
Chant, D.2
McGrath, J.3
-
4
-
-
84884607762
-
Novel approaches to drug design for the treatment of schizophrenia
-
Taly A. Novel approaches to drug design for the treatment of schizophrenia. Exp Opin Drug Discovery.2013;8:1285-1296.
-
(2013)
Exp Opin Drug Discovery.
, vol.8
, pp. 1285-1296
-
-
Taly, A.1
-
6
-
-
25144456112
-
Effectiveness of antipsychotic drugs in patients with chronic schizophrenia
-
Lieberman JA, Stroup TS, McEvoy JP, et al. Effectiveness of antipsychotic drugs in patients with chronic schizophrenia. N Engl J Med. 2005;353:1209-1223.
-
(2005)
N Engl J Med.
, vol.353
, pp. 1209-1223
-
-
Lieberman, J.A.1
Stroup, T.S.2
McEvoy, J.P.3
-
7
-
-
34047146487
-
Effects of antipsychotic medications on psychosocial functioning in patients with chronic schizophrenia: findings from the NIMH CATIE study
-
Swartz MS, Perkins DO, Stroup TS, et al. Effects of antipsychotic medications on psychosocial functioning in patients with chronic schizophrenia: findings from the NIMH CATIE study. Am J Psychiatry. 2007;164:428-436.
-
(2007)
Am J Psychiatry.
, vol.164
, pp. 428-436
-
-
Swartz, M.S.1
Perkins, D.O.2
Stroup, T.S.3
-
8
-
-
79951988420
-
Schizophrenia: treatment targets beyond monoamine systems
-
Ibrahim HM, Tamminga CA. Schizophrenia: treatment targets beyond monoamine systems. Annu Rev Pharmacol Toxicol. 2011;51:189-209.
-
(2011)
Annu Rev Pharmacol Toxicol.
, vol.51
, pp. 189-209
-
-
Ibrahim, H.M.1
Tamminga, C.A.2
-
9
-
-
84884338958
-
Rethinking schizophrenia in the context of normal neurodevelopment
-
Catts VS, Fung SJ, Long LE, et al. Rethinking schizophrenia in the context of normal neurodevelopment. Front Cell Neurosci. 2013;7:60.
-
(2013)
Front Cell Neurosci.
, vol.7
, pp. 60
-
-
Catts, V.S.1
Fung, S.J.2
Long, L.E.3
-
10
-
-
78650426512
-
Stereological approaches to identifying neuropathology in psychosis
-
Dorph-Petersen KA, Lewis DA. Stereological approaches to identifying neuropathology in psychosis. Biol Psychiatry. 2011;69:113-126.
-
(2011)
Biol Psychiatry.
, vol.69
, pp. 113-126
-
-
Dorph-Petersen, K.A.1
Lewis, D.A.2
-
11
-
-
84892659999
-
Boosting the power of schizophrenia genetics by leveraging new statistical tools
-
Andreassen OA, Thompson WK, Dale AM. Boosting the power of schizophrenia genetics by leveraging new statistical tools. Schizophr Bull. 2014;40:13-17.
-
(2014)
Schizophr Bull.
, vol.40
, pp. 13-17
-
-
Andreassen, O.A.1
Thompson, W.K.2
Dale, A.M.3
-
12
-
-
84855926937
-
The genetic architecture of schizophrenia: new mutations and emerging paradigms
-
Rodriguez-Murillo L, Gogos JA, Karayiorgou M. The genetic architecture of schizophrenia: new mutations and emerging paradigms. Annu Rev Med. 2012;63:63-80.
-
(2012)
Annu Rev Med.
, vol.63
, pp. 63-80
-
-
Rodriguez-Murillo, L.1
Gogos, J.A.2
Karayiorgou, M.3
-
13
-
-
84887009499
-
The emerging field of neuroepigenetics
-
Sweatt JD. The emerging field of neuroepigenetics. Neuron. 2013;80:624-632.
-
(2013)
Neuron.
, vol.80
, pp. 624-632
-
-
Sweatt, J.D.1
-
16
-
-
84911406599
-
-
Berlin, Heidelberg, Germany: Springer
-
Petronis A, Mill J. Brain, Behavior, and Epigenetics. Berlin, Heidelberg, Germany: Springer; 2011.
-
(2011)
Brain, Behavior, and Epigenetics
-
-
Petronis, A.1
Mill, J.2
-
18
-
-
84881376767
-
FDG-PET imaging reveals local brain glucose utilization is altered by class I histone deacetylase inhibitors
-
Schroeder FA, Chonde DB, Riley MM, et al. FDG-PET imaging reveals local brain glucose utilization is altered by class I histone deacetylase inhibitors. Neurosci Lett. 2013;550:119-124.
-
(2013)
Neurosci Lett.
, vol.550
, pp. 119-124
-
-
Schroeder, F.A.1
Chonde, D.B.2
Riley, M.M.3
-
19
-
-
84866141733
-
HDAC2 regulates atypical antipsychotic responses through the modulation of mGlu2 promoter activity
-
Kurita M, Holloway T, Garcia-Bea A, et al. HDAC2 regulates atypical antipsychotic responses through the modulation of mGlu2 promoter activity. Nat Neurosci. 2012;15:1245-1254.
-
(2012)
Nat Neurosci.
, vol.15
, pp. 1245-1254
-
-
Kurita, M.1
Holloway, T.2
Garcia-Bea, A.3
-
20
-
-
38649124003
-
Epigenetic targets of HDAC inhibition in neurodegenerative and psychiatric disorders
-
Abel T, Zukin RS. Epigenetic targets of HDAC inhibition in neurodegenerative and psychiatric disorders. Curr Opin Pharmacol. 2008;8:57-64.
-
(2008)
Curr Opin Pharmacol.
, vol.8
, pp. 57-64
-
-
Abel, T.1
Zukin, R.S.2
-
21
-
-
34250026412
-
Histone deacetylase inhibitors enhance memory and synaptic plasticity via CREB:CBP-dependent transcriptional activation
-
Vecsey CG, Hawk JD, Lattal KM, et al. Histone deacetylase inhibitors enhance memory and synaptic plasticity via CREB:CBP-dependent transcriptional activation. J Neurosci. 2007;27:6128-6140.
-
(2007)
J Neurosci.
, vol.27
, pp. 6128-6140
-
-
Vecsey, C.G.1
Hawk, J.D.2
Lattal, K.M.3
-
22
-
-
84864700183
-
Epigenetic mechanisms in neurological disease
-
Jakovcevski M, Akbarian S. Epigenetic mechanisms in neurological disease. Nat Med 2012;18:1194-1204.
-
(2012)
Nat Med
, vol.18
, pp. 1194-1204
-
-
Jakovcevski, M.1
Akbarian, S.2
-
24
-
-
79952384705
-
Cancer epigenetics reaches mainstream oncology
-
Rodriguez-Paredes M, Esteller M. Cancer epigenetics reaches mainstream oncology. Nat Med. 2011;17:330-339.
-
(2011)
Nat Med.
, vol.17
, pp. 330-339
-
-
Rodriguez-Paredes, M.1
Esteller, M.2
-
25
-
-
79953163378
-
Chromatin higher-order structures and gene regulation
-
Li G, Reinberg D. Chromatin higher-order structures and gene regulation. Curr Opin Genet Dev. 2011;21:175-186.
-
(2011)
Curr Opin Genet Dev.
, vol.21
, pp. 175-186
-
-
Li, G.1
Reinberg, D.2
-
26
-
-
78650304236
-
Charting histone modifications and the functional organization of mammalian genomes
-
Zhou VW, Goren A, Bernstein BE. Charting histone modifications and the functional organization of mammalian genomes. Nat Rev Genetics. 2011;12:7-18.
-
(2011)
Nat Rev Genetics.
, vol.12
, pp. 7-18
-
-
Zhou, V.W.1
Goren, A.2
Bernstein, B.E.3
-
28
-
-
79960127277
-
Tissue-specific distribution and dynamic changes of 5-hydroxymethylcytosine in mammalian genomes
-
Kinney SM, Chin HG, Vaisvila R, et al. Tissue-specific distribution and dynamic changes of 5-hydroxymethylcytosine in mammalian genomes. J Biol Chem. 2011;286:24685-24693.
-
(2011)
J Biol Chem.
, vol.286
, pp. 24685-24693
-
-
Kinney, S.M.1
Chin, H.G.2
Vaisvila, R.3
-
29
-
-
66149123748
-
The nuclear DNA base 5-hydroxymethylcytosine is present in Purkinje neurons and the brain
-
Kriaucionis S, Heintz N. The nuclear DNA base 5-hydroxymethylcytosine is present in Purkinje neurons and the brain. Science. 2009;324:929-930.
-
(2009)
Science.
, vol.324
, pp. 929-930
-
-
Kriaucionis, S.1
Heintz, N.2
-
30
-
-
79960249232
-
Genomic mapping of 5-hydroxymethylcytosine in the human brain
-
Jin SG, Wu X, Li AX, Pfeifer GP. Genomic mapping of 5-hydroxymethylcytosine in the human brain. Nucleic Acids Res. 2011;39:5015-5024.
-
(2011)
Nucleic Acids Res.
, vol.39
, pp. 5015-5024
-
-
Jin, S.G.1
Wu, X.2
Li, A.X.3
Pfeifer, G.P.4
-
31
-
-
78651280460
-
Selective chemical labeling reveals the genome-wide distribution of 5-hydroxymethylcytosine
-
Song CX, Szulwach KE, Fu Y, et al. Selective chemical labeling reveals the genome-wide distribution of 5-hydroxymethylcytosine. Nat Biotechnol. 2011;29:68-72.
-
(2011)
Nat Biotechnol.
, vol.29
, pp. 68-72
-
-
Song, C.X.1
Szulwach, K.E.2
Fu, Y.3
-
32
-
-
77954504873
-
Conserved role of intragenic DNA methylation in regulating alternative promoters
-
Maunakea AK, Nagarajan RP, Bilenky M, al. Conserved role of intragenic DNA methylation in regulating alternative promoters. Nature. 2010;466:253-257.
-
(2010)
Nature.
, vol.466
, pp. 253-257
-
-
Maunakea, A.K.1
Nagarajan, R.P.2
Bilenky, M.3
-
33
-
-
24144490659
-
Chromatin, DNA methylation and neuron gene regulation--the purpose of the package
-
Sharma RP, Grayson DR, Guidotti A, Costa E. Chromatin, DNA methylation and neuron gene regulation--the purpose of the package. J Psychiatry Neurosci. 2005;30:257-263.
-
(2005)
J Psychiatry Neurosci.
, vol.30
, pp. 257-263
-
-
Sharma, R.P.1
Grayson, D.R.2
Guidotti, A.3
Costa, E.4
-
34
-
-
80052942443
-
Identification of 67 histone marks and histone lysine crotonylation as a new type of histone modification
-
Tan M, Luo H, Lee S, J et al. Identification of 67 histone marks and histone lysine crotonylation as a new type of histone modification. Cell. 2011;146:1016-1028.
-
(2011)
Cell.
, vol.146
, pp. 1016-1028
-
-
Tan, M.1
Luo, H.2
Lee, S.J.3
-
35
-
-
33847076849
-
Chromatin modifications and their function
-
Kouzarides T. Chromatin modifications and their function. Cell. 2007;128:693-705.
-
(2007)
Cell.
, vol.128
, pp. 693-705
-
-
Kouzarides, T.1
-
36
-
-
35848961668
-
How chromatinbinding modules interpret histone modifications: lessons from professional pocket pickers
-
Taverna SD, Li H, Ruthenburg AJ, Allis CD, Patel DJ. How chromatinbinding modules interpret histone modifications: lessons from professional pocket pickers. Nat Struct Mol Biol. 2007;14:1025-1040.
-
(2007)
Nat Struct Mol Biol.
, vol.14
, pp. 1025-1040
-
-
Taverna, S.D.1
Li, H.2
Ruthenburg, A.J.3
Allis, C.D.4
Patel, D.J.5
-
37
-
-
77953644347
-
Reversal of histone methylation: biochemical and molecular mechanisms of histone demethylases
-
Mosammaparast N, Shi Y. Reversal of histone methylation: biochemical and molecular mechanisms of histone demethylases. Annu Rev Biochem. 2010;79:155-179.
-
(2010)
Annu Rev Biochem.
, vol.79
, pp. 155-179
-
-
Mosammaparast, N.1
Shi, Y.2
-
38
-
-
78649682494
-
Reading, writing and editing methylated lysines on histone tails: new insights from recent structural studies
-
Justin N, De Marco V, Aasland R, Gamblin SJ. Reading, writing and editing methylated lysines on histone tails: new insights from recent structural studies. Curr Opin Struct Biol. 2010: 730-738.
-
(2010)
Curr Opin Struct Biol
, pp. 730-738
-
-
Justin, N.1
De Marco, V.2
Aasland, R.3
Gamblin, S.J.4
-
39
-
-
34250745886
-
Nucleosome stability mediated by histone variants H3.3 and H2A.Z
-
Jin C, Felsenfeld G. Nucleosome stability mediated by histone variants H3.3 and H2A.Z. Genes Dev. 2007;21:1519-1529.
-
(2007)
Genes Dev.
, vol.21
, pp. 1519-1529
-
-
Jin, C.1
Felsenfeld, G.2
-
40
-
-
84887620842
-
A high-resolution map of the three-dimensional chromatin interactome in human cells
-
Jin F, Li Y, Dixon JR, et al. A high-resolution map of the three-dimensional chromatin interactome in human cells. Nature. 2013;503:290-294.
-
(2013)
Nature.
, vol.503
, pp. 290-294
-
-
Jin, F.1
Li, Y.2
Dixon, J.R.3
-
41
-
-
61849100510
-
Alterations in oligodendrocyte proteins, calcium homeostasis and new potential markers in schizophrenia anterior temporal lobe are revealed by shotgun proteome analysis
-
Martins-de-Souza D, Gattaz WF, Schmitt A, et al. Alterations in oligodendrocyte proteins, calcium homeostasis and new potential markers in schizophrenia anterior temporal lobe are revealed by shotgun proteome analysis. J Neural Transm. 2009;116:275-289.
-
(2009)
J Neural Transm.
, vol.116
, pp. 275-289
-
-
Martins-de-Souza, D.1
Gattaz, W.F.2
Schmitt, A.3
-
42
-
-
34249722767
-
Myelin staining of deep white matter in the dorsolateral prefrontal cortex in schizophrenia, bipolar disorder, and unipolar major depression
-
Regenold WT, Phatak P, Marano CM, Gearhart L, Viens CH, Hisley KC. Myelin staining of deep white matter in the dorsolateral prefrontal cortex in schizophrenia, bipolar disorder, and unipolar major depression. Psychiatry Res. 2007;151:179-188.
-
(2007)
Psychiatry Res.
, vol.151
, pp. 179-188
-
-
Regenold, W.T.1
Phatak, P.2
Marano, C.M.3
Gearhart, L.4
Viens, C.H.5
Hisley, K.C.6
-
43
-
-
26844483219
-
Variations in myelin and oligodendrocyte-related gene expression across multiple brain regions in schizophrenia: a gene ontology study
-
Katsel P, Davis KL, Haroutunian V. Variations in myelin and oligodendrocyte-related gene expression across multiple brain regions in schizophrenia: a gene ontology study. Schizophr Res. 2005;79:157-173.
-
(2005)
Schizophr Res.
, vol.79
, pp. 157-173
-
-
Katsel, P.1
Davis, K.L.2
Haroutunian, V.3
-
44
-
-
4444324427
-
Microarray analysis of postmortem temporal cortex from patients with schizophrenia
-
Aston C, Jiang L, Sokolov BP. Microarray analysis of postmortem temporal cortex from patients with schizophrenia. J Neurosci Res. 2004;77:858-866.
-
(2004)
J Neurosci Res.
, vol.77
, pp. 858-866
-
-
Aston, C.1
Jiang, L.2
Sokolov, B.P.3
-
45
-
-
0035836642
-
Genome-wide expression analysis reveals dysregulation of myelination-related genes in chronic schizophrenia
-
Hakak Y, Walker JR, Li C, et al. Genome-wide expression analysis reveals dysregulation of myelination-related genes in chronic schizophrenia. Proc Natl Acad Sci U S A. 2001;98:4746-4751.
-
(2001)
Proc Natl Acad Sci U S A.
, vol.98
, pp. 4746-4751
-
-
Hakak, Y.1
Walker, J.R.2
Li, C.3
-
46
-
-
0041328892
-
Oligodendrocyte dysfunction in schizophrenia and bipolar disorder
-
Tkachev D, Mimmack ML, Ryan MM, et al. Oligodendrocyte dysfunction in schizophrenia and bipolar disorder. Lancet. 2003;362:798-805.
-
(2003)
Lancet.
, vol.362
, pp. 798-805
-
-
Tkachev, D.1
Mimmack, M.L.2
Ryan, M.M.3
-
47
-
-
77954031783
-
Prefrontal GABA(A) receptor alpha-subunit expression in normal postnatal human development and schizophrenia
-
Duncan CE, Webster MJ, Rothmond DA, Bahn S, Elashoff M, Shannon Weickert C. Prefrontal GABA(A) receptor alpha-subunit expression in normal postnatal human development and schizophrenia. J Psychiatr Res. 2010:44:673-681.
-
(2010)
J Psychiatr Res.
, vol.44
, pp. 673-681
-
-
Duncan, C.E.1
Webster, M.J.2
Rothmond, D.A.3
Bahn, S.4
Elashoff, M.5
Shannon Weickert, C.6
-
48
-
-
69849092307
-
GABA(A) receptors and their associated proteins: implications in the etiology and treatment of schizophrenia and related disorders
-
Charych EI, Liu F, Moss SJ, Brandon NJ. GABA(A) receptors and their associated proteins: implications in the etiology and treatment of schizophrenia and related disorders. Neuropharmacology. 2009;57:481-495.
-
(2009)
Neuropharmacology.
, vol.57
, pp. 481-495
-
-
Charych, E.I.1
Liu, F.2
Moss, S.J.3
Brandon, N.J.4
-
49
-
-
46349084319
-
Disease-specific alterations in glutamatergic neurotransmission on inhibitory interneurons in the prefrontal cortex in schizophrenia
-
Woo TU, Kim AM, Viscidi E. Disease-specific alterations in glutamatergic neurotransmission on inhibitory interneurons in the prefrontal cortex in schizophrenia. Brain Res. 2008;1218:267-277.
-
(2008)
Brain Res.
, vol.1218
, pp. 267-277
-
-
Woo, T.U.1
Kim, A.M.2
Viscidi, E.3
-
50
-
-
33747872904
-
Molecular and cellular mechanisms of altered GAD1/GAD67 expression in schizophrenia and related disorders
-
Akbarian S, Huang HS. Molecular and cellular mechanisms of altered GAD1/GAD67 expression in schizophrenia and related disorders. Brain Res Rev. 2006;52:293-304.
-
(2006)
Brain Res Rev.
, vol.52
, pp. 293-304
-
-
Akbarian, S.1
Huang, H.S.2
-
51
-
-
21344438862
-
GABAergic dysfunction in schizophrenia: new treatment strategies on the horizon
-
Guidotti A, Auta J, Davis JM, et al. GABAergic dysfunction in schizophrenia: new treatment strategies on the horizon. Psychopharmacology. 2005;180:191-205.
-
(2005)
Psychopharmacology.
, vol.180
, pp. 191-205
-
-
Guidotti, A.1
Auta, J.2
Davis, J.M.3
-
52
-
-
2342471419
-
GAD67 and GAD65 mRNA and protein expression in cerebrocortical regions of elderly patients with schizophrenia
-
Dracheva S, Elhakem SL, McGurk SR, Davis KL, Haroutunian V. GAD67 and GAD65 mRNA and protein expression in cerebrocortical regions of elderly patients with schizophrenia. J Neurosci Res. 2004;76:581-592.
-
(2004)
J Neurosci Res.
, vol.76
, pp. 581-592
-
-
Dracheva, S.1
Elhakem, S.L.2
McGurk, S.R.3
Davis, K.L.4
Haroutunian, V.5
-
53
-
-
43349105701
-
Conserved regional patterns of GABA-related transcript expression in the neocortex of subjects with schizophrenia
-
Hashimoto T, Bazmi HH, Mirnics K, Wu Q, Sampson AR, Lewis DA. Conserved regional patterns of GABA-related transcript expression in the neocortex of subjects with schizophrenia. Am J Psychiatry. 2008;165:479-489.
-
(2008)
Am J Psychiatry.
, vol.165
, pp. 479-489
-
-
Hashimoto, T.1
Bazmi, H.H.2
Mirnics, K.3
Wu, Q.4
Sampson, A.R.5
Lewis, D.A.6
-
54
-
-
72049105340
-
Amygdalocortical circuitry in schizophrenia: from circuits to molecules
-
Benes FM. Amygdalocortical circuitry in schizophrenia: from circuits to molecules. Neuropsychopharmacology. 2010;35:239-257.
-
(2010)
Neuropsychopharmacology.
, vol.35
, pp. 239-257
-
-
Benes, F.M.1
-
55
-
-
34547916833
-
Abnormal glutamate receptor expression in the medial temporal lobe in schizophrenia and mood disorders
-
Beneyto M, Kristiansen LV, Oni-Orisan A, McCullumsmith RE, Meador-Woodruff JH. Abnormal glutamate receptor expression in the medial temporal lobe in schizophrenia and mood disorders. Neuropsychopharmacology. 2007;32:1888-1902.
-
(2007)
Neuropsychopharmacology.
, vol.32
, pp. 1888-1902
-
-
Beneyto, M.1
Kristiansen, L.V.2
Oni-Orisan, A.3
McCullumsmith, R.E.4
Meador-Woodruff, J.H.5
-
56
-
-
0034094628
-
Glutamate receptor expression in schizophrenic brain
-
Meador-Woodruff JH, Healy DJ. Glutamate receptor expression in schizophrenic brain. Brain Res Rev. 2000;31:288-294.
-
(2000)
Brain Res Rev.
, vol.31
, pp. 288-294
-
-
Meador-Woodruff, J.H.1
Healy, D.J.2
-
57
-
-
0036307210
-
Gene expression profile for schizophrenia: discrete neuron transcription patterns in the entorhinal cortex
-
Hemby SE, Ginsberg SD, Brunk B, Arnold SE, Trojanowski JQ, Eberwine JH. Gene expression profile for schizophrenia: discrete neuron transcription patterns in the entorhinal cortex. Arch Gen Psychiatry. 2002;59:631-640.
-
(2002)
Arch Gen Psychiatry.
, vol.59
, pp. 631-640
-
-
Hemby, S.E.1
Ginsberg, S.D.2
Brunk, B.3
Arnold, S.E.4
Trojanowski, J.Q.5
Eberwine, J.H.6
-
58
-
-
0033637841
-
Molecular characterization of schizophrenia viewed by microarray analysis of gene expression in prefrontal cortex
-
Mirnics K, Middleton FA, Marquez A, Lewis DA, Levitt P. Molecular characterization of schizophrenia viewed by microarray analysis of gene expression in prefrontal cortex. Neuron. 2000;28:53-67.
-
(2000)
Neuron.
, vol.28
, pp. 53-67
-
-
Mirnics, K.1
Middleton, F.A.2
Marquez, A.3
Lewis, D.A.4
Levitt, P.5
-
59
-
-
0036550998
-
Gene expression profiling reveals alterations of specific metabolic pathways in schizophrenia
-
Middleton FA, Mirnics K, Pierri JN, Lewis DA, Levitt P. Gene expression profiling reveals alterations of specific metabolic pathways in schizophrenia. J Neurosci. 2002;22:2718-2729.
-
(2002)
J Neurosci.
, vol.22
, pp. 2718-2729
-
-
Middleton, F.A.1
Mirnics, K.2
Pierri, J.N.3
Lewis, D.A.4
Levitt, P.5
-
60
-
-
84898853930
-
Neuron-specific chromatin remodeling: A missing link in epigenetic mechanisms underlying synaptic plasticity, memory, and intellectual disability disorders
-
Vogel-Ciernia A, Wood MA. Neuron-specific chromatin remodeling: A missing link in epigenetic mechanisms underlying synaptic plasticity, memory, and intellectual disability disorders. Neuropharmacology. 2014;80:18-27.
-
(2014)
Neuropharmacology.
, vol.80
, pp. 18-27
-
-
Vogel-Ciernia, A.1
Wood, M.A.2
-
61
-
-
84898850226
-
Decoding transcriptional repressor complexes in the adult central nervous system
-
Adachi M, Monteggia LM. Decoding transcriptional repressor complexes in the adult central nervous system. Neuropharmacology. 2014.80:45-52.
-
(2014)
Neuropharmacology.
, vol.80
, pp. 45-52
-
-
Adachi, M.1
Monteggia, L.M.2
-
62
-
-
20144373163
-
Hypermethylation of the reelin (RELN) promoter in the brain of schizophrenic patients: a preliminary report
-
Abdolmaleky HM, Cheng KH, Russo A, et al. Hypermethylation of the reelin (RELN) promoter in the brain of schizophrenic patients: a preliminary report. Am J Med Genet B Neuropsychiatr Genet. 2005;134:60-66.
-
(2005)
Am J Med Genet B Neuropsychiatr Genet.
, vol.134
, pp. 60-66
-
-
Abdolmaleky, H.M.1
Cheng, K.H.2
Russo, A.3
-
63
-
-
21544433777
-
Reelin promoter hypermethylation in schizophrenia
-
Grayson DR, Jia X, Chen Y, et al. Reelin promoter hypermethylation in schizophrenia. Proc Natl Acad Sci U S A. 2005;102:9341-9346.
-
(2005)
Proc Natl Acad Sci U S A.
, vol.102
, pp. 9341-9346
-
-
Grayson, D.R.1
Jia, X.2
Chen, Y.3
-
64
-
-
20044389866
-
DNA methylation status of SOX10 correlates with its downregulation and oligodendrocyte dysfunction in schizophrenia
-
Iwamoto K, Bundo M, Yamada K, et al. DNA methylation status of SOX10 correlates with its downregulation and oligodendrocyte dysfunction in schizophrenia. J Neurosci. 2005;25:5376-5381.
-
(2005)
J Neurosci.
, vol.25
, pp. 5376-5381
-
-
Iwamoto, K.1
Bundo, M.2
Yamada, K.3
-
65
-
-
84255200543
-
Disease-and age-related changes in histone acetylation at gene promoters in psychiatric disorders
-
Tang B, Dean B, Thomas EA. Disease-and age-related changes in histone acetylation at gene promoters in psychiatric disorders. Transl Psychiatry. 2011;1:e64.
-
(2011)
Transl Psychiatry.
, vol.1
-
-
Tang, B.1
Dean, B.2
Thomas, E.A.3
-
66
-
-
35448944724
-
Prefrontal dysfunction in schizophrenia involves mixed-lineage leukemia 1-regulated histone methylation at GABAergic gene promoters
-
Huang HS, Matevossian A, Whittle C, et al. Prefrontal dysfunction in schizophrenia involves mixed-lineage leukemia 1-regulated histone methylation at GABAergic gene promoters. J Neurosci. 2007;27:11254-11262.
-
(2007)
J Neurosci.
, vol.27
, pp. 11254-11262
-
-
Huang, H.S.1
Matevossian, A.2
Whittle, C.3
-
67
-
-
84896732939
-
Methylome-Wide Association study of schizophrenia: identifying blood biomarker signatures of environmental insults
-
Aberg KA, McClay JL, Nerella S,et al. Methylome-Wide Association study of schizophrenia: identifying blood biomarker signatures of environmental insults. JAMA Psychiatry. 2014;71:255-264.
-
(2014)
JAMA Psychiatry.
, vol.71
, pp. 255-264
-
-
Aberg, K.A.1
McClay, J.L.2
Nerella, S.3
-
68
-
-
67349238734
-
Histone deacetylase inhibitors and candidate gene expression: An in vivo and in vitro approach to studying chromatin remodeling in a clinical population
-
Gavin DP, Kartan S, Chase K, Jayaraman S, Sharma RP. Histone deacetylase inhibitors and candidate gene expression: An in vivo and in vitro approach to studying chromatin remodeling in a clinical population. J Psych Res. 2009;43:870-876.
-
(2009)
J Psych Res.
, vol.43
, pp. 870-876
-
-
Gavin, D.P.1
Kartan, S.2
Chase, K.3
Jayaraman, S.4
Sharma, R.P.5
-
69
-
-
84884131438
-
DNA-methylation gene network dysregulation in peripheral blood lymphocytes of schizophrenia patients
-
Auta J, Smith RC, Dong E, et al. DNA-methylation gene network dysregulation in peripheral blood lymphocytes of schizophrenia patients. Schizophr Res. 2013;150:312-318.
-
(2013)
Schizophr Res.
, vol.150
, pp. 312-318
-
-
Auta, J.1
Smith, R.C.2
Dong, E.3
-
70
-
-
84880867623
-
DNA methylation of the BDNF gene and its relevance to psychiatric disorders
-
Ikegame T, Bundo M, Murata Y, Kasai K, Kato T, Iwamoto K. DNA methylation of the BDNF gene and its relevance to psychiatric disorders. J Hum Genet. 2013;58:434-438.
-
(2013)
J Hum Genet.
, vol.58
, pp. 434-438
-
-
Ikegame, T.1
Bundo, M.2
Murata, Y.3
Kasai, K.4
Kato, T.5
Iwamoto, K.6
-
71
-
-
84876724680
-
Genome-wide profiling of multiple histone methylations in olfactory cells: further implications for cellular susceptibility to oxidative stress in schizophrenia
-
Kano S, Colantuoni C, Han F, et al. Genome-wide profiling of multiple histone methylations in olfactory cells: further implications for cellular susceptibility to oxidative stress in schizophrenia. Mol Psychiatry. 2013;18:740-742.
-
(2013)
Mol Psychiatry.
, vol.18
, pp. 740-742
-
-
Kano, S.1
Colantuoni, C.2
Han, F.3
-
72
-
-
81855183787
-
Disease-associated epigenetic changes in monozygotic twins discordant for schizophrenia and bipolar disorder
-
Dempster EL, Pidsley R, Schalkwyk LC, et al. Disease-associated epigenetic changes in monozygotic twins discordant for schizophrenia and bipolar disorder. Hum Mol Genet. 2011;20:4786-4796.
-
(2011)
Hum Mol Genet.
, vol.20
, pp. 4786-4796
-
-
Dempster, E.L.1
Pidsley, R.2
Schalkwyk, L.C.3
-
73
-
-
41149140859
-
Epigenomic profiling reveals DNA-methylation changes associated with major psychosis
-
Mill J, Tang T, Kaminsky Z, Khare T, et al. Epigenomic profiling reveals DNA-methylation changes associated with major psychosis. Am J Hum Genet. 2008;82:696-711.
-
(2008)
Am J Hum Genet.
, vol.82
, pp. 696-711
-
-
Mill, J.1
Tang, T.2
Kaminsky, Z.3
Khare, T.4
-
74
-
-
84893135952
-
Genome-wide DNA methylation analysis of human brain tissue from schizophrenia patients
-
Wockner LF, Noble EP, Lawford BR, et al. Genome-wide DNA methylation analysis of human brain tissue from schizophrenia patients. Transl Psychiatry. 2014;4:e339.
-
(2014)
Transl Psychiatry.
, vol.4
-
-
Wockner, L.F.1
Noble, E.P.2
Lawford, B.R.3
-
75
-
-
84884829249
-
Mapping human epigenomes
-
Rivera CM, Ren B. Mapping human epigenomes. Cell. 2013;155:39-55.
-
(2013)
Cell.
, vol.155
, pp. 39-55
-
-
Rivera, C.M.1
Ren, B.2
-
76
-
-
84877827977
-
IT Future of medicine: from molecular analysis to clinical diagnosis and improved treatment
-
Zazzu V, Regierer B, Kuhn A, Sudbrak R, Lehrach H. IT Future of medicine: from molecular analysis to clinical diagnosis and improved treatment. New Biotechnol. 2013;30:362-365.
-
(2013)
New Biotechnol.
, vol.30
, pp. 362-365
-
-
Zazzu, V.1
Regierer, B.2
Kuhn, A.3
Sudbrak, R.4
Lehrach, H.5
-
77
-
-
84899544568
-
Regulatory genomic regions active in immune cell types explain a large proportion of the genetic risk of multiple sclerosis
-
Elangovan RI, Disanto G, Berlanga-Taylor AJ, Ramagopalan SV, Handunnetthi L. Regulatory genomic regions active in immune cell types explain a large proportion of the genetic risk of multiple sclerosis. J Hum Genet. 2014;59:211-215.
-
(2014)
J Hum Genet.
, vol.59
, pp. 211-215
-
-
Elangovan, R.I.1
Disanto, G.2
Berlanga-Taylor, A.J.3
Ramagopalan, S.V.4
Handunnetthi, L.5
-
78
-
-
84857062545
-
DNA methylation signatures in development and aging of the human prefrontal cortex
-
Numata S, Ye T, Hyde TM, et al. DNA methylation signatures in development and aging of the human prefrontal cortex. Am J Hum Genet. 2012;90:260-272.
-
(2012)
Am J Hum Genet.
, vol.90
, pp. 260-272
-
-
Numata, S.1
Ye, T.2
Hyde, T.M.3
-
79
-
-
77649204292
-
Genetic control of individual differences in gene-specific methylation in human brain
-
Zhang D, Cheng L, Badner JA, et al. Genetic control of individual differences in gene-specific methylation in human brain. Am J Hum Genet. 2010;86:411-419.
-
(2010)
Am J Hum Genet.
, vol.86
, pp. 411-419
-
-
Zhang, D.1
Cheng, L.2
Badner, J.A.3
-
80
-
-
84891819951
-
Genetics of psychiatric disorders in the GWAS era: an update on schizophrenia
-
Schwab SG, Wildenauer DB. Genetics of psychiatric disorders in the GWAS era: an update on schizophrenia. Eur Arch Psychiatry Clin Neurosci. 2013;263(suppl 2):S147-S154.
-
(2013)
Eur Arch Psychiatry Clin Neurosci.
, vol.263
, pp. S147-S154
-
-
Schwab, S.G.1
Wildenauer, D.B.2
-
81
-
-
84885020424
-
Genome-wide association analysis identifies 13 new risk loci for schizophrenia
-
Ripke S, O'Dushlaine C, Chambert K, et al. Genome-wide association analysis identifies 13 new risk loci for schizophrenia. Nat Genet. 2013;45:1150-1159.
-
(2013)
Nat Genet.
, vol.45
, pp. 1150-1159
-
-
Ripke, S.1
O'Dushlaine, C.2
Chambert, K.3
-
82
-
-
83055171565
-
Downregulation of parvalbumin at cortical GABA synapses reduces network gamma oscillatory activity
-
Volman V, Behrens MM, Sejnowski TJ. Downregulation of parvalbumin at cortical GABA synapses reduces network gamma oscillatory activity. J Neurosci. 2011;31:18137-18148.
-
(2011)
J Neurosci.
, vol.31
, pp. 18137-18148
-
-
Volman, V.1
Behrens, M.M.2
Sejnowski, T.J.3
-
83
-
-
84856857477
-
Cortical basket cell dysfunction in schizophrenia
-
Curley AA, Lewis DA. Cortical basket cell dysfunction in schizophrenia. J Physiol. 2012;590(Pt 4):715-724.
-
(2012)
J Physiol.
, vol.590
, pp. 715-724
-
-
Curley, A.A.1
Lewis, D.A.2
-
84
-
-
34547209903
-
Regulation of the GABA cell phenotype in hippocampus of schizophrenics and bipolars
-
Benes FM, Lim B, Matzilevich D, Walsh JP, Subburaju S, Minns M. Regulation of the GABA cell phenotype in hippocampus of schizophrenics and bipolars. Proc Natl Acad Sci U S A. 2007;104:10164-10169.
-
(2007)
Proc Natl Acad Sci U S A.
, vol.104
, pp. 10164-10169
-
-
Benes, F.M.1
Lim, B.2
Matzilevich, D.3
Walsh, J.P.4
Subburaju, S.5
Minns, M.6
-
85
-
-
0033759439
-
Decrease in reelin and glutamic acid decarboxylase67 (GAD67) expression in schizophrenia and bipolar disorder: a postmortem brain study
-
Guidotti A, Auta J, Davis JM, et al. Decrease in reelin and glutamic acid decarboxylase67 (GAD67) expression in schizophrenia and bipolar disorder: a postmortem brain study. Arch Gen Psychiatry. 2000;57:1061-1069.
-
(2000)
Arch Gen Psychiatry.
, vol.57
, pp. 1061-1069
-
-
Guidotti, A.1
Auta, J.2
Davis, J.M.3
-
86
-
-
80053029201
-
Alterations in GABAergic biomarkers in the autism brain: research findings and clinical implications
-
Blatt GJ, Fatemi SH. Alterations in GABAergic biomarkers in the autism brain: research findings and clinical implications. Anat Rec. 2011;294:1646-1652.
-
(2011)
Anat Rec.
, vol.294
, pp. 1646-1652
-
-
Blatt, G.J.1
Fatemi, S.H.2
-
87
-
-
0028948389
-
Gene expression for glutamic acid decarboxylase is reduced without loss of neurons in prefrontal cortex of schizophrenics
-
Akbarian S, Kim JJ, Potkin SG, Hagman JO, Tafazzoli A, Bunney WE, Jr., et al. Gene expression for glutamic acid decarboxylase is reduced without loss of neurons in prefrontal cortex of schizophrenics. Arch Gen Psychiatry. 1995;52:258-266.
-
(1995)
Arch Gen Psychiatry.
, vol.52
, pp. 258-266
-
-
Akbarian, S.1
Kim, J.J.2
Potkin, S.G.3
Hagman, J.O.4
Tafazzoli, A.5
Bunney Jr., W.E.6
-
88
-
-
21244501298
-
GAD1 (2q31.1), which encodes glutamic acid decarboxylase (GAD67), is associated with childhood-onset schizophrenia and cortical gray matter volume loss
-
Addington AM, Gornick M, Duckworth J, Sporn A, Gogtay N, Bobb A, et al. GAD1 (2q31.1), which encodes glutamic acid decarboxylase (GAD67), is associated with childhood-onset schizophrenia and cortical gray matter volume loss. Mol Psychiatry. 2005;10:581-588.
-
(2005)
Mol Psychiatry.
, vol.10
, pp. 581-588
-
-
Addington, A.M.1
Gornick, M.2
Duckworth, J.3
Sporn, A.4
Gogtay, N.5
Bobb, A.6
-
89
-
-
34548303921
-
Allelic variation in GAD1 (GAD67) is associated with schizophrenia and influences cortical function and gene expression
-
Straub RE, Lipska BK, Egan MF, Goldberg TE, Kleinman JE, Weinberger DR. Allelic variation in GAD1 (GAD67) is associated with schizophrenia and influences cortical function and gene expression. Mol Psychiatry. 2007; 12:854-869.
-
(2007)
Mol Psychiatry.
, vol.12
, pp. 854-869
-
-
Straub, R.E.1
Lipska, B.K.2
Egan, M.F.3
Goldberg, T.E.4
Kleinman, J.E.5
Weinberger, D.R.6
-
90
-
-
77953594619
-
Genetic modulation of GABA levels in the anterior cingulate cortex by GAD1 and COMT
-
Marenco S, Savostyanova AA, van der Veen JW, et al. Genetic modulation of GABA levels in the anterior cingulate cortex by GAD1 and COMT. Neuropsychopharmacology. 2010;35:1708-1717.
-
(2010)
Neuropsychopharmacology.
, vol.35
, pp. 1708-1717
-
-
Marenco, S.1
Savostyanova, A.A.2
van der Veen, J.W.3
-
91
-
-
84880430125
-
Conserved chromosome 2q31 conformations are associated with transcriptional regulation of GAD1 GABA synthesis enzyme and altered in prefrontal cortex of subjects with schizophrenia
-
Bharadwaj R, Jiang Y, Mao W, et al. Conserved chromosome 2q31 conformations are associated with transcriptional regulation of GAD1 GABA synthesis enzyme and altered in prefrontal cortex of subjects with schizophrenia. J Neurosci. 2013;33:11839-11851.
-
(2013)
J Neurosci.
, vol.33
, pp. 11839-11851
-
-
Bharadwaj, R.1
Jiang, Y.2
Mao, W.3
-
92
-
-
84895430208
-
Converging genetic and functional brain imaging evidence links neuronal excitability to working memory, psychiatric disease, and brain activity
-
Heck A, Fastenrath M, Ackermann S, et al. Converging genetic and functional brain imaging evidence links neuronal excitability to working memory, psychiatric disease, and brain activity. Neuron. 2014;81:1203-1213.
-
(2014)
Neuron.
, vol.81
, pp. 1203-1213
-
-
Heck, A.1
Fastenrath, M.2
Ackermann, S.3
-
93
-
-
76749090671
-
Epigenetics and the biological definition of gene x environment interactions
-
Meaney MJ. Epigenetics and the biological definition of gene x environment interactions. Child Dev. 2010;81:41-79.
-
(2010)
Child Dev.
, vol.81
, pp. 41-79
-
-
Meaney, M.J.1
-
94
-
-
79952123263
-
Maternal infection and schizophrenia: implications for prevention
-
Brown AS, Patterson PH. Maternal infection and schizophrenia: implications for prevention. Schizophr Bull. 2011;37:284-290.
-
(2011)
Schizophr Bull.
, vol.37
, pp. 284-290
-
-
Brown, A.S.1
Patterson, P.H.2
-
95
-
-
84898026391
-
The impact of environmental factors in severe psychiatric disorders
-
Schmitt A, Malchow B, Hasan A, Falkai P. The impact of environmental factors in severe psychiatric disorders. Front Neurosci. 2014;8:19.
-
(2014)
Front Neurosci.
, vol.8
, pp. 19
-
-
Schmitt, A.1
Malchow, B.2
Hasan, A.3
Falkai, P.4
-
96
-
-
41149090082
-
DNA methylation in the human cerebral cortex is dynamically regulated throughout the life span and involves differentiated neurons
-
Siegmund KD, Connor CM, Campan M, et al. DNA methylation in the human cerebral cortex is dynamically regulated throughout the life span and involves differentiated neurons. PloS One. 2007;2:e895.
-
(2007)
PloS One.
, vol.2
-
-
Siegmund, K.D.1
Connor, C.M.2
Campan, M.3
-
97
-
-
84876886897
-
Coordinated cell type-specific epigenetic remodeling in prefrontal cortex begins before birth and continues into early adulthood
-
Shulha HP, Cheung I, Guo Y, Akbarian S, Weng Z. Coordinated cell type-specific epigenetic remodeling in prefrontal cortex begins before birth and continues into early adulthood. PLoS Genetics. 2013;9:e1003433.
-
(2013)
PLoS Genetics.
, vol.9
-
-
Shulha, H.P.1
Cheung, I.2
Guo, Y.3
Akbarian, S.4
Weng, Z.5
-
98
-
-
77952715009
-
Developmental regulation and individual differences of neuronal H3K4me3 epigenomes in the prefrontal cortex
-
Cheung I, Shulha HP, Jiang Y, Matevossian A, Wang J, Weng Z, et al. Developmental regulation and individual differences of neuronal H3K4me3 epigenomes in the prefrontal cortex. Proc Natl Acad Sci U S A. 2010;107:8824-8829.
-
(2010)
Proc Natl Acad Sci U S A.
, vol.107
, pp. 8824-8829
-
-
Cheung, I.1
Shulha, H.P.2
Jiang, Y.3
Matevossian, A.4
Wang, J.5
Weng, Z.6
-
99
-
-
84879663784
-
Global epigenomic reconfiguration during mammalian brain development
-
Lister R, Mukamel EA, Nery JR, et al. Global epigenomic reconfiguration during mammalian brain development. Science. 2013;341:1237905.
-
(2013)
Science.
, vol.341
, pp. 1237905
-
-
Lister, R.1
Mukamel, E.A.2
Nery, J.R.3
-
100
-
-
60749105468
-
Epigenetic regulation of the glucocorticoid receptor in human brain associates with childhood abuse
-
McGowan PO, Sasaki A, D'Alessio AC, Dymov S, Labonte B, Szyf M, et al. Epigenetic regulation of the glucocorticoid receptor in human brain associates with childhood abuse. Nat Neurosci. 2009;12:342-348.
-
(2009)
Nat Neurosci.
, vol.12
, pp. 342-348
-
-
McGowan, P.O.1
Sasaki, A.2
D'Alessio, A.C.3
Dymov, S.4
Labonte, B.5
Szyf, M.6
-
101
-
-
84855300158
-
Genome-wide epigenetic regulation by early-life trauma
-
Labonte B, Suderman M, Maussion G, et al. Genome-wide epigenetic regulation by early-life trauma. Arch Gen Psychiatry. 2012;69:722-731.
-
(2012)
Arch Gen Psychiatry.
, vol.69
, pp. 722-731
-
-
Labonte, B.1
Suderman, M.2
Maussion, G.3
-
102
-
-
84862027231
-
Differential glucocorticoid receptor exon 1(B), 1(C), and 1(H) expression and methylation in suicide completers with a history of childhood abuse
-
Labonte B, Yerko V, Gross J, et al. Differential glucocorticoid receptor exon 1(B), 1(C), and 1(H) expression and methylation in suicide completers with a history of childhood abuse. Biol Psychiatry. 2012;72:41-48.
-
(2012)
Biol Psychiatry.
, vol.72
, pp. 41-48
-
-
Labonte, B.1
Yerko, V.2
Gross, J.3
-
103
-
-
47749133462
-
Promoter-wide hypermethylation of the ribosomal RNA gene promoter in the suicide brain
-
McGowan PO, Sasaki A, Huang TC, et al. Promoter-wide hypermethylation of the ribosomal RNA gene promoter in the suicide brain. PloS One. 2008;3:e2085.
-
(2008)
PloS One.
, vol.3
-
-
McGowan, P.O.1
Sasaki, A.2
Huang, T.C.3
-
104
-
-
80052449957
-
Cortical deficits of glutamic acid decarboxylase 67 expression in schizophrenia: clinical, protein, and cell type-specific features
-
Curley AA, Arion D, Volk DW, et al. Cortical deficits of glutamic acid decarboxylase 67 expression in schizophrenia: clinical, protein, and cell type-specific features. Am J Psychiatry. 2011;168:921-929.
-
(2011)
Am J Psychiatry.
, vol.168
, pp. 921-929
-
-
Curley, A.A.1
Arion, D.2
Volk, D.W.3
-
105
-
-
79960950456
-
Expression of GABA signaling molecules KCC2, NKCC1, and GAD1 in cortical development and schizophrenia
-
Hyde TM, Lipska BK, Ali T, Mathew SV, Law AJ, Metitiri OE, et al. Expression of GABA signaling molecules KCC2, NKCC1, and GAD1 in cortical development and schizophrenia. J Neurosci. 2011;31:11088-11095.
-
(2011)
J Neurosci.
, vol.31
, pp. 11088-11095
-
-
Hyde, T.M.1
Lipska, B.K.2
Ali, T.3
Mathew, S.V.4
Law, A.J.5
Metitiri, O.E.6
-
106
-
-
77956689355
-
Maternal care and DNA methylation of a glutamic acid decarboxylase 1 promoter in rat hippocampus
-
Zhang TY, Hellstrom IC, Bagot RC, Wen X, Diorio J, Meaney MJ. Maternal care and DNA methylation of a glutamic acid decarboxylase 1 promoter in rat hippocampus. J Neurosci. 2010;30:13130-13137.
-
(2010)
J Neurosci.
, vol.30
, pp. 13130-13137
-
-
Zhang, T.Y.1
Hellstrom, I.C.2
Bagot, R.C.3
Wen, X.4
Diorio, J.5
Meaney, M.J.6
-
107
-
-
84893637754
-
Prenatal MAM administration affects histone H3 methylation in postnatal life in the rat medial prefrontal cortex
-
Mackowiak M, Bator E, Latusz J, Mordalska P, Wedzony K. Prenatal MAM administration affects histone H3 methylation in postnatal life in the rat medial prefrontal cortex. Eur Neuropsychopharmacol. 2014;24:271-289.
-
(2014)
Eur Neuropsychopharmacol.
, vol.24
, pp. 271-289
-
-
Mackowiak, M.1
Bator, E.2
Latusz, J.3
Mordalska, P.4
Wedzony, K.5
-
108
-
-
38649094308
-
GAD1 mRNA expression and DNA methylation in prefrontal cortex of subjects with schizophrenia
-
Huang HS, Akbarian S. GAD1 mRNA expression and DNA methylation in prefrontal cortex of subjects with schizophrenia. PloS One. 2007;2:e809.
-
(2007)
PloS One.
, vol.2
-
-
Huang, H.S.1
Akbarian, S.2
-
109
-
-
84895756661
-
Prenatal immune activation induces maturation-dependent alterations in the prefrontal GABAergic transcriptome
-
Richetto J, Calabrese F, Riva MA, Meyer U. Prenatal immune activation induces maturation-dependent alterations in the prefrontal GABAergic transcriptome. Schizophr Bull. 2014;40:351-361.
-
(2014)
Schizophr Bull.
, vol.40
, pp. 351-361
-
-
Richetto, J.1
Calabrese, F.2
Riva, M.A.3
Meyer, U.4
-
110
-
-
84876885338
-
Epigenetic changes at gene promoters in response to immune activation in utero
-
Tang B, Jia H, Kast RJ, Thomas EA. Epigenetic changes at gene promoters in response to immune activation in utero. Brain Behav Immun. 2013;30:168-175.
-
(2013)
Brain Behav Immun.
, vol.30
, pp. 168-175
-
-
Tang, B.1
Jia, H.2
Kast, R.J.3
Thomas, E.A.4
-
111
-
-
84865313397
-
Maternal immune activation alters behavior in adult offspring, with subtle changes in the cortical transcriptome and epigenome
-
Connor CM, Dincer A, Straubhaar J, Galler JR, Houston IB, Akbarian S. Maternal immune activation alters behavior in adult offspring, with subtle changes in the cortical transcriptome and epigenome. Schizophr Res. 2012;140:175-184.
-
(2012)
Schizophr Res.
, vol.140
, pp. 175-184
-
-
Connor, C.M.1
Dincer, A.2
Straubhaar, J.3
Galler, J.R.4
Houston, I.B.5
Akbarian, S.6
-
112
-
-
84872443390
-
Adolescent stress-induced epigenetic control of dopaminergic neurons via glucocorticoids
-
Niwa M, Jaaro-Peled H, Tankou S, et al. Adolescent stress-induced epigenetic control of dopaminergic neurons via glucocorticoids. Science. 2013;339:335-339.
-
(2013)
Science.
, vol.339
, pp. 335-339
-
-
Niwa, M.1
Jaaro-Peled, H.2
Tankou, S.3
-
113
-
-
55849115277
-
Nicotine decreases DNA methyltransferase 1 expression and glutamic acid decarboxylase 67 promoter methylation in GABAergic interneurons
-
Satta R, Maloku E, Zhubi A, et al. Nicotine decreases DNA methyltransferase 1 expression and glutamic acid decarboxylase 67 promoter methylation in GABAergic interneurons. Proc Natl Acad Sci U S A. 2008;105:16356-16361.
-
(2008)
Proc Natl Acad Sci U S A.
, vol.105
, pp. 16356-16361
-
-
Satta, R.1
Maloku, E.2
Zhubi, A.3
-
114
-
-
79955989168
-
Selective alpha4beta2 nicotinic acetylcholine receptor agonists target epigenetic mechanisms in cortical GABAergic neurons
-
Maloku E, Kadriu B, Zhubi A, et al. Selective alpha4beta2 nicotinic acetylcholine receptor agonists target epigenetic mechanisms in cortical GABAergic neurons. Neuropsychopharmacology. 2011;36:1366-1374.
-
(2011)
Neuropsychopharmacology.
, vol.36
, pp. 1366-1374
-
-
Maloku, E.1
Kadriu, B.2
Zhubi, A.3
-
115
-
-
84876686460
-
From neural development to cognition: unexpected roles for chromatin
-
Ronan JL, Wu W, Crabtree GR. From neural development to cognition: unexpected roles for chromatin. Nat Rev Genetics. 2013;14:347-359.
-
(2013)
Nat Rev Genetics.
, vol.14
, pp. 347-359
-
-
Ronan, J.L.1
Wu, W.2
Crabtree, G.R.3
-
116
-
-
79957623760
-
Mutations in DNMT1 cause hereditary sensory neuropathy with dementia and hearing loss
-
Klein CJ, Botuyan MV, Wu Y, et al. Mutations in DNMT1 cause hereditary sensory neuropathy with dementia and hearing loss. Nat Genet. 2011;43:595-600.
-
(2011)
Nat Genet.
, vol.43
, pp. 595-600
-
-
Klein, C.J.1
Botuyan, M.V.2
Wu, Y.3
-
117
-
-
84860491605
-
Mutations in DNMT1 cause autosomal dominant cerebellar ataxia, deafness and narcolepsy
-
Winkelmann J, Lin L, Schormair B, et al. Mutations in DNMT1 cause autosomal dominant cerebellar ataxia, deafness and narcolepsy. Hum Mol Genet. 2012;2:2205-2210.
-
(2012)
Hum Mol Genet.
, vol.2
, pp. 2205-2210
-
-
Winkelmann, J.1
Lin, L.2
Schormair, B.3
-
118
-
-
0036371289
-
MECP2 mutation in a boy with language disorder and schizophrenia
-
Cohen D, Lazar G, Couvert P, et al. MECP2 mutation in a boy with language disorder and schizophrenia. Am J Psychiatry. 2002;159:148-149.
-
(2002)
Am J Psychiatry.
, vol.159
, pp. 148-149
-
-
Cohen, D.1
Lazar, G.2
Couvert, P.3
-
119
-
-
79960837617
-
Systematic resequencing of X-chromosome synaptic genes in autism spectrum disorder and schizophrenia
-
Piton A, Gauthier J, Hamdan FF, Lafreniere RG, Yang Y, Henrion E, et al. Systematic resequencing of X-chromosome synaptic genes in autism spectrum disorder and schizophrenia. Mol Psychiatry. 2011;16:867-880.
-
(2011)
Mol Psychiatry.
, vol.16
, pp. 867-880
-
-
Piton, A.1
Gauthier, J.2
Hamdan, F.F.3
Lafreniere, R.G.4
Yang, Y.5
Henrion, E.6
-
120
-
-
84856225986
-
De novo CNV analysis implicates specific abnormalities of postsynaptic signalling complexes in the pathogenesis of schizophrenia
-
Kirov G, Pocklington AJ, Holmans P, et al. De novo CNV analysis implicates specific abnormalities of postsynaptic signalling complexes in the pathogenesis of schizophrenia. Mol Psychiatry. 2012;17:142-153.
-
(2012)
Mol Psychiatry.
, vol.17
, pp. 142-153
-
-
Kirov, G.1
Pocklington, A.J.2
Holmans, P.3
-
121
-
-
84863485112
-
Microduplications disrupting the MYT1L gene (2p25.3) are associated with schizophrenia
-
Lee Y, Mattai A, Long R, Rapoport JL, Gogtay N, Addington AM. Microduplications disrupting the MYT1L gene (2p25.3) are associated with schizophrenia. Psychiatr Genet. 2012;22:206-209.
-
(2012)
Psychiatr Genet.
, vol.22
, pp. 206-209
-
-
Lee, Y.1
Mattai, A.2
Long, R.3
Rapoport, J.L.4
Gogtay, N.5
Addington, A.M.6
-
122
-
-
84892654670
-
Protein-protein interaction and pathway analyses of top schizophrenia genes reveal schizophrenia susceptibility genes converge on common molecular networks and enrichment of nucleosome (chromatin) assembly genes in schizophrenia susceptibility loci
-
Luo X, Huang L, Jia P, Li M, Su B, Zhao Z, et al. Protein-protein interaction and pathway analyses of top schizophrenia genes reveal schizophrenia susceptibility genes converge on common molecular networks and enrichment of nucleosome (chromatin) assembly genes in schizophrenia susceptibility loci. Schizophr Bull. 2014;40:39-49.
-
(2014)
Schizophr Bull.
, vol.40
, pp. 39-49
-
-
Luo, X.1
Huang, L.2
Jia, P.3
Li, M.4
Su, B.5
Zhao, Z.6
-
123
-
-
84870529525
-
Diverse types of genetic variation converge on functional gene networks involved in schizophrenia
-
Gilman SR, Chang J, Xu B, et al. Diverse types of genetic variation converge on functional gene networks involved in schizophrenia. Nat Neurosci. 2012;15:1723-1728.
-
(2012)
Nat Neurosci.
, vol.15
, pp. 1723-1728
-
-
Gilman, S.R.1
Chang, J.2
Xu, B.3
-
124
-
-
0016239099
-
The leucocyte antigenic system HL-A as a possible genetic marker of schizophrenia
-
Cazzullo CL, Smeraldi E, Penati G. The leucocyte antigenic system HL-A as a possible genetic marker of schizophrenia. Br J Psychiatry. 1974;125:25-27.
-
(1974)
Br J Psychiatry.
, vol.125
, pp. 25-27
-
-
Cazzullo, C.L.1
Smeraldi, E.2
Penati, G.3
-
125
-
-
84892620489
-
Genome-wide Association studies: findings at the major histocompatibility complex locus in psychosis
-
Corvin A, Morris DW. Genome-wide Association studies: findings at the major histocompatibility complex locus in psychosis. Biol Psychiatry. 2014;75:276-283.
-
(2014)
Biol Psychiatry.
, vol.75
, pp. 276-283
-
-
Corvin, A.1
Morris, D.W.2
-
126
-
-
84888155351
-
Transcriptome study of differential expression in schizophrenia
-
Sanders AR, Goring HH, Duan J, et al. Transcriptome study of differential expression in schizophrenia. Hum Mol Genet. 2013;22:5001-5014.
-
(2013)
Hum Mol Genet.
, vol.22
, pp. 5001-5014
-
-
Sanders, A.R.1
Goring, H.H.2
Duan, J.3
-
127
-
-
84901291138
-
The genome in three dimensions: a new frontier in human brain research
-
Mitchell AC, Bharadwaj R, Whittle C, et al. The genome in three dimensions: a new frontier in human brain research. Biol Psychiatry. 2014;75:961-969.
-
(2014)
Biol Psychiatry.
, vol.75
, pp. 961-969
-
-
Mitchell, A.C.1
Bharadwaj, R.2
Whittle, C.3
-
129
-
-
79951988420
-
Schizophrenia: treatment targets beyond monoamine systems
-
Ibrahim HM, Tamminga CA. Schizophrenia: treatment targets beyond monoamine systems. Annu Rev Pharmacol Toxicol. 2011;51:189-209.
-
(2011)
Annu Rev Pharmacol Toxicol.
, vol.51
, pp. 189-209
-
-
Ibrahim, H.M.1
Tamminga, C.A.2
-
131
-
-
4444382918
-
Dopamine D2-like antagonists induce chromatin remodeling in striatal neurons through cyclic AMP-protein kinase A and NMDA receptor signaling
-
Li J, Guo Y, Schroeder FA, et al. Dopamine D2-like antagonists induce chromatin remodeling in striatal neurons through cyclic AMP-protein kinase A and NMDA receptor signaling. J Neurochem. 2004;90:1117-1131.
-
(2004)
J Neurochem.
, vol.90
, pp. 1117-1131
-
-
Li, J.1
Guo, Y.2
Schroeder, F.A.3
-
132
-
-
51649127761
-
Clozapine and sulpiride but not haloperidol or olanzapine activate brain DNA demethylation
-
Dong E, Nelson M, Grayson DR, Costa E, Guidotti A. Clozapine and sulpiride but not haloperidol or olanzapine activate brain DNA demethylation. Proc Natl Acad Sci U S A. 2008;105:13614-13649.
-
(2008)
Proc Natl Acad Sci U S A.
, vol.105
, pp. 13614-13649
-
-
Dong, E.1
Nelson, M.2
Grayson, D.R.3
Costa, E.4
Guidotti, A.5
-
133
-
-
33748286212
-
Crystal structure of a glycerate kinase (TM1585) from Thermotoga maritima at 2.70 A resolution reveals a new fold
-
Schwarzenbacher R, McMullan D, Krishna SS, et al. Crystal structure of a glycerate kinase (TM1585) from Thermotoga maritima at 2.70 A resolution reveals a new fold. Proteins. 2006;65:243-248.
-
(2006)
Proteins.
, vol.65
, pp. 243-248
-
-
Schwarzenbacher, R.1
McMullan, D.2
Krishna, S.S.3
-
134
-
-
36048958965
-
Histone deacetylase inhibitors: overview and perspectives
-
Dokmanovic M, Clarke C, Marks PA. Histone deacetylase inhibitors: overview and perspectives. Mol Cancer Res. 2007;5:981-989.
-
(2007)
Mol Cancer Res.
, vol.5
, pp. 981-989
-
-
Dokmanovic, M.1
Clarke, C.2
Marks, P.A.3
-
135
-
-
84879124659
-
Epigenetic dysregulation in schizophrenia: molecular and clinical aspects of histone deacetylase inhibitors
-
Hasan A, Mitchell A, Schneider A, Halene T, Akbarian S. Epigenetic dysregulation in schizophrenia: molecular and clinical aspects of histone deacetylase inhibitors. Eur Arch Psychiatry Clin Neurosci. 2013;263:273-284.
-
(2013)
Eur Arch Psychiatry Clin Neurosci.
, vol.263
, pp. 273-284
-
-
Hasan, A.1
Mitchell, A.2
Schneider, A.3
Halene, T.4
Akbarian, S.5
-
136
-
-
36849063138
-
Histone deactylase 1 expression is increased in the prefrontal cortex of schizophrenia subjects: analysis of the National Brain Databank microarray collection
-
Sharma RP, Grayson DR, Gavin DP. Histone deactylase 1 expression is increased in the prefrontal cortex of schizophrenia subjects: analysis of the National Brain Databank microarray collection. Schizophr Res. 2008;98:111-117.
-
(2008)
Schizophr Res.
, vol.98
, pp. 111-117
-
-
Sharma, R.P.1
Grayson, D.R.2
Gavin, D.P.3
-
137
-
-
53949085543
-
Molecular profiles of schizophrenia in the CNS at different stages of illness
-
Narayan S, Tang B, Head SR, et al. Molecular profiles of schizophrenia in the CNS at different stages of illness. Brain Res. 2008;1239:235-248.
-
(2008)
Brain Res.
, vol.1239
, pp. 235-248
-
-
Narayan, S.1
Tang, B.2
Head, S.R.3
-
138
-
-
84885430428
-
Prefrontal cortical dysfunction after overexpression of histone deacetylase 1
-
Jakovcevski M, Bharadwaj R, Straubhaar J, et al. Prefrontal cortical dysfunction after overexpression of histone deacetylase 1. Biol Psychiatry. 2013;74:696-705.
-
(2013)
Biol Psychiatry.
, vol.74
, pp. 696-705
-
-
Jakovcevski, M.1
Bharadwaj, R.2
Straubhaar, J.3
-
139
-
-
84876010140
-
Loss of histone deacetylase 2 improves working memory and accelerates extinction learning
-
Morris MJ, Mahgoub M, Na ES, Pranav H, Monteggia LM. Loss of histone deacetylase 2 improves working memory and accelerates extinction learning. J Neurosci. 2013;33:6401-6411.
-
(2013)
J Neurosci.
, vol.33
, pp. 6401-6411
-
-
Morris, M.J.1
Mahgoub, M.2
Na, E.S.3
Pranav, H.4
Monteggia, L.M.5
-
140
-
-
84876784737
-
Administration of MS-275 improves cognitive performance and reduces cell death following traumatic brain injury in rats
-
Cao P, Liang Y, Gao X, Zhao MG, Liang GB. Administration of MS-275 improves cognitive performance and reduces cell death following traumatic brain injury in rats. CNS Neurosci Ther. 2013;19:337-345.
-
(2013)
CNS Neurosci Ther.
, vol.19
, pp. 337-345
-
-
Cao, P.1
Liang, Y.2
Gao, X.3
Zhao, M.G.4
Liang, G.B.5
-
141
-
-
84874661821
-
Oral administration of histone deacetylase inhibitor MS-275 ameliorates neuroinflammation and cerebral amyloidosis and improves behavior in a mouse model
-
Zhang ZY, Schluesener HJ. Oral administration of histone deacetylase inhibitor MS-275 ameliorates neuroinflammation and cerebral amyloidosis and improves behavior in a mouse model. J Neuropathol Exp Neurol. 2013;72:178-185.
-
(2013)
J Neuropathol Exp Neurol.
, vol.72
, pp. 178-185
-
-
Zhang, Z.Y.1
Schluesener, H.J.2
-
142
-
-
74549200467
-
Is there a future for histone deacetylase inhibitors in the pharmacotherapy of psychiatric disorders?
-
Grayson DR, Kundakovic M, Sharma RP. Is there a future for histone deacetylase inhibitors in the pharmacotherapy of psychiatric disorders? Mol Pharmacol. 2010;77:126-135.
-
(2010)
Mol Pharmacol.
, vol.77
, pp. 126-135
-
-
Grayson, D.R.1
Kundakovic, M.2
Sharma, R.P.3
-
143
-
-
34250161829
-
Antidepressant-like effects of the histone deacetylase inhibitor, sodium butyrate, in the mouse
-
Schroeder FA, Lin CL, Crusio WE, Akbarian S. Antidepressant-like effects of the histone deacetylase inhibitor, sodium butyrate, in the mouse. Biol Psychiatry. 2007;62:55-64.
-
(2007)
Biol Psychiatry.
, vol.62
, pp. 55-64
-
-
Schroeder, F.A.1
Lin, C.L.2
Crusio, W.E.3
Akbarian, S.4
-
144
-
-
57549099873
-
Antidepressant-like effects of sodium butyrate in combination with estrogen in rat forced swimming test: involvement of 5-HT(1A) receptors
-
Zhu H, Huang Q, Xu H, Niu L, Zhou JN. Antidepressant-like effects of sodium butyrate in combination with estrogen in rat forced swimming test: involvement of 5-HT(1A) receptors. Behav Brain Res. 2009;196:200-206.
-
(2009)
Behav Brain Res.
, vol.196
, pp. 200-206
-
-
Zhu, H.1
Huang, Q.2
Xu, H.3
Niu, L.4
Zhou, J.N.5
-
145
-
-
79952902253
-
Hippocampal-dependent antidepressant-like activity of histone deacetylase inhibition
-
Covington HE, 3rd, Vialou VF, LaPlant Q, Ohnishi YN, Nestler EJ. Hippocampal-dependent antidepressant-like activity of histone deacetylase inhibition. Neurosci Lett. 2011;493:122-126.
-
(2011)
Neurosci Lett.
, vol.493
, pp. 122-126
-
-
Covington I.I.I, H.E.1
Vialou, V.F.2
LaPlant, Q.3
Ohnishi, Y.N.4
Nestler, E.J.5
-
146
-
-
84862777829
-
Molecular mechanisms associated with the antidepressant effects of the class I histone deacetylase inhibitor MS-275 in the rat ventrolateral orbital cortex
-
Lin H, Geng X, Dang W, et al. Molecular mechanisms associated with the antidepressant effects of the class I histone deacetylase inhibitor MS-275 in the rat ventrolateral orbital cortex. Brain Res. 2012;1447:119-125.
-
(2012)
Brain Res.
, vol.1447
, pp. 119-125
-
-
Lin, H.1
Geng, X.2
Dang, W.3
-
147
-
-
84859181036
-
Histone recognition and large-scale structural analysis of the human bromodomain family
-
Filippakopoulos P, Picaud S, Mangos M, et al. Histone recognition and large-scale structural analysis of the human bromodomain family. Cell. 2012;149:214-231.
-
(2012)
Cell.
, vol.149
, pp. 214-231
-
-
Filippakopoulos, P.1
Picaud, S.2
Mangos, M.3
-
148
-
-
84886808679
-
Chromatin proteins and modifications as drug targets
-
Helin K, Dhanak D. Chromatin proteins and modifications as drug targets. Nature. 2013;502:480-488.
-
(2013)
Nature.
, vol.502
, pp. 480-488
-
-
Helin, K.1
Dhanak, D.2
-
149
-
-
84860236448
-
Electroconvulsive seizures regulates the Brd1 gene in the frontal cortex and hippocampus of the adult rat
-
Fryland T, Elfving B, Christensen JH, Mors O, Wegener G, Borglum AD. Electroconvulsive seizures regulates the Brd1 gene in the frontal cortex and hippocampus of the adult rat. Neurosci Lett. 2012;516:110-113.
-
(2012)
Neurosci Lett.
, vol.516
, pp. 110-113
-
-
Fryland, T.1
Elfving, B.2
Christensen, J.H.3
Mors, O.4
Wegener, G.5
Borglum, A.D.6
|