메뉴 건너뛰기




Volumn 39, Issue 1, 2010, Pages 73-84

Epigenetics, hippocampal neurogenesis, and neuropsychiatric disorders: Unraveling the genome to understand the mind

Author keywords

Adult neurogenesis; Chromatin; Depression; Epigenetics; Learning and memory; Neural stem cell

Indexed keywords

DISRUPTED IN SCHIZOPHRENIA 1 PROTEIN; FLUOXETINE; HISTONE DEACETYLASE 1; HISTONE DEACETYLASE 2; HISTONE H3; IMIPRAMINE; MEMANTINE; MONOAMINE OXIDASE INHIBITOR; NESTIN; NORADRENALIN; REBOXETINE; SEROTONIN UPTAKE INHIBITOR; TRANSCRIPTION FACTOR SOX2; TRANYLCYPROMINE; VALPROIC ACID;

EID: 77952887349     PISSN: 09699961     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.nbd.2010.01.008     Document Type: Review
Times cited : (126)

References (202)
  • 1
    • 15544370150 scopus 로고    scopus 로고
    • Adult neurogenesis: from precursors to network and physiology
    • Abrous D.N., et al. Adult neurogenesis: from precursors to network and physiology. Physiol. Rev. 2005, 85:523-569.
    • (2005) Physiol. Rev. , vol.85 , pp. 523-569
    • Abrous, D.N.1
  • 2
    • 65249109439 scopus 로고    scopus 로고
    • MeCP2-mediated transcription repression in the basolateral amygdala may underlie heightened anxiety in a mouse model of Rett syndrome
    • Adachi M., et al. MeCP2-mediated transcription repression in the basolateral amygdala may underlie heightened anxiety in a mouse model of Rett syndrome. J. Neurosci. 2009, 29:4218-4227.
    • (2009) J. Neurosci. , vol.29 , pp. 4218-4227
    • Adachi, M.1
  • 3
    • 2942705826 scopus 로고    scopus 로고
    • Chromatin acetylation, memory, and LTP are impaired in CBP+/Ž mice: a model for the cognitive deficit in Rubinstein-Taybi syndrome and its amelioration
    • Alarcon J.M., et al. Chromatin acetylation, memory, and LTP are impaired in CBP+/Ž mice: a model for the cognitive deficit in Rubinstein-Taybi syndrome and its amelioration. Neuron 2004, 42:947-959.
    • (2004) Neuron , vol.42 , pp. 947-959
    • Alarcon, J.M.1
  • 4
    • 45749111428 scopus 로고    scopus 로고
    • The loss of methyl-CpG binding protein 1 leads to autism-like behavioral deficits
    • Allan A.M., et al. The loss of methyl-CpG binding protein 1 leads to autism-like behavioral deficits. Hum. Mol. Genet. 2008, 17:2047-2057.
    • (2008) Hum. Mol. Genet. , vol.17 , pp. 2047-2057
    • Allan, A.M.1
  • 5
    • 0032830639 scopus 로고    scopus 로고
    • Rett syndrome is caused by mutations in X-linked MECP2, encoding methyl-CpG-binding protein 2
    • Amir R.E., et al. Rett syndrome is caused by mutations in X-linked MECP2, encoding methyl-CpG-binding protein 2. Nat. Genet. 1999, 23:185-188.
    • (1999) Nat. Genet. , vol.23 , pp. 185-188
    • Amir, R.E.1
  • 6
    • 4644305290 scopus 로고    scopus 로고
    • Neurogenesis in the subventricular zone following transcranial magnetic field stimulation and nigrostriatal lesions
    • Arias-Carrion O., et al. Neurogenesis in the subventricular zone following transcranial magnetic field stimulation and nigrostriatal lesions. J. Neurosci. Res. 2004, 78:16-28.
    • (2004) J. Neurosci. Res. , vol.78 , pp. 16-28
    • Arias-Carrion, O.1
  • 7
    • 19344378337 scopus 로고    scopus 로고
    • REST and its corepressors mediate plasticity of neuronal gene chromatin throughout neurogenesis
    • Ballas N., et al. REST and its corepressors mediate plasticity of neuronal gene chromatin throughout neurogenesis. Cell 2005, 121:645-657.
    • (2005) Cell , vol.121 , pp. 645-657
    • Ballas, N.1
  • 8
    • 33746255997 scopus 로고    scopus 로고
    • Identification of astrocyte-expressed factors that modulate neural stem/progenitor cell differentiation
    • Barkho B.Z., et al. Identification of astrocyte-expressed factors that modulate neural stem/progenitor cell differentiation. Stem Cells Dev. 2006, 15:407-421.
    • (2006) Stem Cells Dev. , vol.15 , pp. 407-421
    • Barkho, B.Z.1
  • 9
    • 33846933274 scopus 로고    scopus 로고
    • Gadd45a promotes epigenetic gene activation by repair-mediated DNA demethylation
    • Barreto G., et al. Gadd45a promotes epigenetic gene activation by repair-mediated DNA demethylation. Nature 2007, 445:671-675.
    • (2007) Nature , vol.445 , pp. 671-675
    • Barreto, G.1
  • 10
    • 0036719162 scopus 로고    scopus 로고
    • Excitatory actions of gaba during development: the nature of the nurture
    • Ben-Ari Y. Excitatory actions of gaba during development: the nature of the nurture. Nat. Rev. Neurosci. 2002, 3:728-739.
    • (2002) Nat. Rev. Neurosci. , vol.3 , pp. 728-739
    • Ben-Ari, Y.1
  • 11
    • 33646070846 scopus 로고    scopus 로고
    • A bivalent chromatin structure marks key developmental genes in embryonic stem cells
    • Bernstein B.E., et al. A bivalent chromatin structure marks key developmental genes in embryonic stem cells. Cell 2006, 125:315-326.
    • (2006) Cell , vol.125 , pp. 315-326
    • Bernstein, B.E.1
  • 12
    • 0035905766 scopus 로고    scopus 로고
    • Role for a bidentate ribonuclease in the initiation step of RNA interference
    • Bernstein E., et al. Role for a bidentate ribonuclease in the initiation step of RNA interference. Nature 2001, 409:363-366.
    • (2001) Nature , vol.409 , pp. 363-366
    • Bernstein, E.1
  • 13
    • 70349118076 scopus 로고    scopus 로고
    • Antidepressants increase neural progenitor cells in the human hippocampus
    • Boldrini M., et al. Antidepressants increase neural progenitor cells in the human hippocampus. Neuropsychopharmacology 2009, 34:2376-2389.
    • (2009) Neuropsychopharmacology , vol.34 , pp. 2376-2389
    • Boldrini, M.1
  • 14
    • 68149182666 scopus 로고    scopus 로고
    • Balanced gene regulation by an embryonic brain ncRNA is critical for adult hippocampal GABA circuitry
    • Bond A.M., et al. Balanced gene regulation by an embryonic brain ncRNA is critical for adult hippocampal GABA circuitry. Nat. Neurosci. 2009, 12:1020-1027.
    • (2009) Nat. Neurosci. , vol.12 , pp. 1020-1027
    • Bond, A.M.1
  • 15
    • 3542999278 scopus 로고    scopus 로고
    • VEGF links hippocampal activity with neurogenesis, learning and memory
    • Cao L., et al. VEGF links hippocampal activity with neurogenesis, learning and memory. Nat. Genet. 2004, 36:827-835.
    • (2004) Nat. Genet. , vol.36 , pp. 827-835
    • Cao, L.1
  • 16
    • 33745602880 scopus 로고    scopus 로고
    • Noncoding RNAs in the mammalian central nervous system
    • Cao X., et al. Noncoding RNAs in the mammalian central nervous system. Annu. Rev. Neurosci. 2006, 29:77-103.
    • (2006) Annu. Rev. Neurosci. , vol.29 , pp. 77-103
    • Cao, X.1
  • 17
    • 33947180884 scopus 로고    scopus 로고
    • A functional study of miR-124 in the developing neural tube
    • Cao X., et al. A functional study of miR-124 in the developing neural tube. Genes Dev. 2007, 21:531-536.
    • (2007) Genes Dev. , vol.21 , pp. 531-536
    • Cao, X.1
  • 18
    • 33746256453 scopus 로고    scopus 로고
    • Fluoxetine and cocaine induce the epigenetic factors MeCP2 and MBD1 in adult rat brain
    • Cassel S., et al. Fluoxetine and cocaine induce the epigenetic factors MeCP2 and MBD1 in adult rat brain. Mol. Pharmacol. 2006, 70:487-492.
    • (2006) Mol. Pharmacol. , vol.70 , pp. 487-492
    • Cassel, S.1
  • 19
    • 33846903377 scopus 로고    scopus 로고
    • Role of neurotrophic factors in depression
    • Castren E., et al. Role of neurotrophic factors in depression. Curr. Opin. Pharmacol. 2007, 7:18-21.
    • (2007) Curr. Opin. Pharmacol. , vol.7 , pp. 18-21
    • Castren, E.1
  • 20
    • 74149092037 scopus 로고    scopus 로고
    • Effects of lamotrigine and topiramate on hippocampal neurogenesis in experimental temporal-lobe epilepsy
    • Chen J., et al. Effects of lamotrigine and topiramate on hippocampal neurogenesis in experimental temporal-lobe epilepsy. Brain Res. 2009, 1313:270-282.
    • (2009) Brain Res. , vol.1313 , pp. 270-282
    • Chen, J.1
  • 21
    • 65849476475 scopus 로고    scopus 로고
    • MRG15, a component of HAT and HDAC complexes, is essential for proliferation and differentiation of neural precursor cells
    • Chen M., et al. MRG15, a component of HAT and HDAC complexes, is essential for proliferation and differentiation of neural precursor cells. J. Neurosci. Res. 2009, 87:1522-1531.
    • (2009) J. Neurosci. Res. , vol.87 , pp. 1522-1531
    • Chen, M.1
  • 22
    • 63649138643 scopus 로고    scopus 로고
    • MiR-124 regulates adult neurogenesis in the subventricular zone stem cell niche
    • Cheng L.C., et al. miR-124 regulates adult neurogenesis in the subventricular zone stem cell niche. Nat. Neurosci. 2009, 12:399-408.
    • (2009) Nat. Neurosci. , vol.12 , pp. 399-408
    • Cheng, L.C.1
  • 23
    • 37549066339 scopus 로고    scopus 로고
    • Members of the miRNA-200 family regulate olfactory neurogenesis
    • Choi P.S., et al. Members of the miRNA-200 family regulate olfactory neurogenesis. Neuron 2008, 57:41-55.
    • (2008) Neuron , vol.57 , pp. 41-55
    • Choi, P.S.1
  • 24
    • 67650450542 scopus 로고    scopus 로고
    • A functional role for adult hippocampal neurogenesis in spatial pattern separation
    • Clelland C.D., et al. A functional role for adult hippocampal neurogenesis in spatial pattern separation. Science 2009, 325:210-213.
    • (2009) Science , vol.325 , pp. 210-213
    • Clelland, C.D.1
  • 25
    • 33144481470 scopus 로고    scopus 로고
    • Reciprocal actions of REST and a microRNA promote neuronal identity
    • Conaco C., et al. Reciprocal actions of REST and a microRNA promote neuronal identity. Proc. Natl. Acad. Sci. U. S. A. 2006, 103:2422-2427.
    • (2006) Proc. Natl. Acad. Sci. U. S. A. , vol.103 , pp. 2422-2427
    • Conaco, C.1
  • 26
    • 66349120438 scopus 로고    scopus 로고
    • Chromatin learns to behave
    • Crepaldi L., Riccio A. Chromatin learns to behave. Epigenetics 2009, 4:23-26.
    • (2009) Epigenetics , vol.4 , pp. 23-26
    • Crepaldi, L.1    Riccio, A.2
  • 27
    • 0035940496 scopus 로고    scopus 로고
    • Stress-induced changes in cerebral metabolites, hippocampal volume, and cell proliferation are prevented by antidepressant treatment with tianeptine
    • Czeh B., et al. Stress-induced changes in cerebral metabolites, hippocampal volume, and cell proliferation are prevented by antidepressant treatment with tianeptine. Proc. Natl. Acad. Sci. U. S. A. 2001, 98:12796-12801.
    • (2001) Proc. Natl. Acad. Sci. U. S. A. , vol.98 , pp. 12796-12801
    • Czeh, B.1
  • 28
    • 44949139634 scopus 로고    scopus 로고
    • Dicer inactivation leads to progressive functional and structural degeneration of the mouse retina
    • Damiani D., et al. Dicer inactivation leads to progressive functional and structural degeneration of the mouse retina. J. Neurosci. 2008, 28:4878-4887.
    • (2008) J. Neurosci. , vol.28 , pp. 4878-4887
    • Damiani, D.1
  • 29
    • 52449093930 scopus 로고    scopus 로고
    • Postnatal and adult neurogenesis in the development of human disease
    • Danzer S.C. Postnatal and adult neurogenesis in the development of human disease. Neuroscientist 2008, 14:446-458.
    • (2008) Neuroscientist , vol.14 , pp. 446-458
    • Danzer, S.C.1
  • 30
    • 65649125633 scopus 로고    scopus 로고
    • Neurogenesis-dependent and -independent effects of fluoxetine in an animal model of anxiety/depression
    • David D.J., et al. Neurogenesis-dependent and -independent effects of fluoxetine in an animal model of anxiety/depression. Neuron 2009, 62:479-493.
    • (2009) Neuron , vol.62 , pp. 479-493
    • David, D.J.1
  • 31
    • 43749120042 scopus 로고    scopus 로고
    • Conditional loss of Dicer disrupts cellular and tissue morphogenesis in the cortex and hippocampus
    • Davis T.H., et al. Conditional loss of Dicer disrupts cellular and tissue morphogenesis in the cortex and hippocampus. J. Neurosci. 2008, 28:4322-4330.
    • (2008) J. Neurosci. , vol.28 , pp. 4322-4330
    • Davis, T.H.1
  • 32
    • 77649338801 scopus 로고    scopus 로고
    • Hippocampal neurogenesis as a target for the treatment of mental illness: a critical evaluation. Neuropharmacology 58, 884--893.
    • DeCarolis, N. A., Eisch, A. J., 2010. Hippocampal neurogenesis as a target for the treatment of mental illness: a critical evaluation. Neuropharmacology 58, 884--893.
    • (2010)
    • DeCarolis, N.A.1    Eisch, A.J.2
  • 33
    • 24644457566 scopus 로고    scopus 로고
    • GABA excitation in the adult brain: a mechanism for excitation-neurogenesis coupling
    • Deisseroth K., Malenka R.C. GABA excitation in the adult brain: a mechanism for excitation-neurogenesis coupling. Neuron 2005, 47:775-777.
    • (2005) Neuron , vol.47 , pp. 775-777
    • Deisseroth, K.1    Malenka, R.C.2
  • 34
    • 2442477425 scopus 로고    scopus 로고
    • Excitation-neurogenesis coupling in adult neural stem/progenitor cells
    • Deisseroth K., et al. Excitation-neurogenesis coupling in adult neural stem/progenitor cells. Neuron 2004, 42:535-552.
    • (2004) Neuron , vol.42 , pp. 535-552
    • Deisseroth, K.1
  • 35
    • 70350537113 scopus 로고    scopus 로고
    • Adult-born hippocampal dentate granule cells undergoing maturation modulate learning and memory in the brain
    • Deng W., et al. Adult-born hippocampal dentate granule cells undergoing maturation modulate learning and memory in the brain. J. Neurosci. 2009, 29:13532-13542.
    • (2009) J. Neurosci. , vol.29 , pp. 13532-13542
    • Deng, W.1
  • 36
    • 33748310866 scopus 로고    scopus 로고
    • Detection of mammalian microRNA expression by in situ hybridization with RNA oligonucleotides
    • Deo M., et al. Detection of mammalian microRNA expression by in situ hybridization with RNA oligonucleotides. Dev. Dyn. 2006, 235:2538-2548.
    • (2006) Dev. Dyn. , vol.235 , pp. 2538-2548
    • Deo, M.1
  • 37
    • 33646145721 scopus 로고    scopus 로고
    • Circadian regulator CLOCK is a histone acetyltransferase
    • Doi M., et al. Circadian regulator CLOCK is a histone acetyltransferase. Cell 2006, 125:497-508.
    • (2006) Cell , vol.125 , pp. 497-508
    • Doi, M.1
  • 38
    • 32544460592 scopus 로고    scopus 로고
    • Decreased adult hippocampal neurogenesis in the PDAPP mouse model of Alzheimer's disease
    • Donovan M.H., et al. Decreased adult hippocampal neurogenesis in the PDAPP mouse model of Alzheimer's disease. J. Comp. Neurol. 2006, 495:70-83.
    • (2006) J. Comp. Neurol. , vol.495 , pp. 70-83
    • Donovan, M.H.1
  • 39
    • 34548806900 scopus 로고    scopus 로고
    • Disrupted-in-schizophrenia 1 regulates integration of newly generated neurons in the adult brain
    • Duan X., et al. Disrupted-in-schizophrenia 1 regulates integration of newly generated neurons in the adult brain. Cell 2007, 130:1146-1158.
    • (2007) Cell , vol.130 , pp. 1146-1158
    • Duan, X.1
  • 40
    • 45849151100 scopus 로고    scopus 로고
    • Spatial relational memory requires hippocampal adult neurogenesis
    • Dupret D., et al. Spatial relational memory requires hippocampal adult neurogenesis. PLoS ONE 2008, e1959:3.
    • (2008) PLoS ONE , vol.1959 e , pp. 3
    • Dupret, D.1
  • 41
    • 58149343358 scopus 로고    scopus 로고
    • Adult neurogenesis, mental health, and mental illness: hope or hypeŽ
    • Eisch A.J., et al. Adult neurogenesis, mental health, and mental illness: hope or hype?. J. Neurosci. 2008, 28:11785-11791.
    • (2008) J. Neurosci. , vol.28 , pp. 11785-11791
    • Eisch, A.J.1
  • 42
    • 0035109547 scopus 로고    scopus 로고
    • DNA hypomethylation perturbs the function and survival of CNS neurons in postnatal animals
    • Fan G., et al. DNA hypomethylation perturbs the function and survival of CNS neurons in postnatal animals. J. Neurosci. 2001, 21:788-797.
    • (2001) J. Neurosci. , vol.21 , pp. 788-797
    • Fan, G.1
  • 43
    • 24344472335 scopus 로고    scopus 로고
    • DNA methylation controls the timing of astrogliogenesis through regulation of JAK-STAT signaling
    • Fan G., et al. DNA methylation controls the timing of astrogliogenesis through regulation of JAK-STAT signaling. Development 2005, 132:3345-3356.
    • (2005) Development , vol.132 , pp. 3345-3356
    • Fan, G.1
  • 44
    • 61849144426 scopus 로고    scopus 로고
    • Bmi-1 cooperates with Foxg1 to maintain neural stem cell self-renewal in the forebrain
    • Fasano C.A., et al. Bmi-1 cooperates with Foxg1 to maintain neural stem cell self-renewal in the forebrain. Genes Dev. 2009, 23:561-574.
    • (2009) Genes Dev. , vol.23 , pp. 561-574
    • Fasano, C.A.1
  • 45
    • 33744804277 scopus 로고    scopus 로고
    • The Evf-2 noncoding RNA is transcribed from the Dlx-5/6 ultraconserved region and functions as a Dlx-2 transcriptional coactivator
    • Feng J., et al. The Evf-2 noncoding RNA is transcribed from the Dlx-5/6 ultraconserved region and functions as a Dlx-2 transcriptional coactivator. Genes Dev. 2006, 20:1470-1484.
    • (2006) Genes Dev. , vol.20 , pp. 1470-1484
    • Feng, J.1
  • 46
    • 16444381345 scopus 로고    scopus 로고
    • Dynamic expression of de novo DNA methyltransferases Dnmt3a and Dnmt3b in the central nervous system
    • Feng J., et al. Dynamic expression of de novo DNA methyltransferases Dnmt3a and Dnmt3b in the central nervous system. J. Neurosci. Res. 2005, 79:734-746.
    • (2005) J. Neurosci. Res. , vol.79 , pp. 734-746
    • Feng, J.1
  • 47
    • 69449107409 scopus 로고    scopus 로고
    • Neurod1 is essential for the survival and maturation of adult-born neurons
    • Gao Z., et al. Neurod1 is essential for the survival and maturation of adult-born neurons. Nat. Neurosci. 2009, 12:1090-1092.
    • (2009) Nat. Neurosci. , vol.12 , pp. 1090-1092
    • Gao, Z.1
  • 48
    • 65549133778 scopus 로고    scopus 로고
    • Adult-generated hippocampal neurons allow the flexible use of spatially precise learning strategies
    • Garthe A., et al. Adult-generated hippocampal neurons allow the flexible use of spatially precise learning strategies. PLoS ONE 2009, e5464:4.
    • (2009) PLoS ONE , vol.5464 e , pp. 4
    • Garthe, A.1
  • 49
    • 31844447757 scopus 로고    scopus 로고
    • GABA regulates synaptic integration of newly generated neurons in the adult brain
    • Ge S., et al. GABA regulates synaptic integration of newly generated neurons in the adult brain. Nature 2006, 439:589-593.
    • (2006) Nature , vol.439 , pp. 589-593
    • Ge, S.1
  • 50
    • 75949085273 scopus 로고    scopus 로고
    • NG2+/Olig2+ cells are the major cycle-related cell population of the adult human normal brain
    • Geha S., et al. NG2+/Olig2+ cells are the major cycle-related cell population of the adult human normal brain. Brain Pathol. 2009, 20:399-411.
    • (2009) Brain Pathol. , vol.20 , pp. 399-411
    • Geha, S.1
  • 51
    • 59249109669 scopus 로고    scopus 로고
    • DNA demethylation by DNA repair
    • Gehring M., et al. DNA demethylation by DNA repair. Trends Genet. 2009, 25:82-90.
    • (2009) Trends Genet. , vol.25 , pp. 82-90
    • Gehring, M.1
  • 52
    • 0030772115 scopus 로고    scopus 로고
    • Functions of mammalian Polycomb group and trithorax group related genes
    • Gould A. Functions of mammalian Polycomb group and trithorax group related genes. Curr. Opin. Genet. Dev. 1997, 7:488-494.
    • (1997) Curr. Opin. Genet. Dev. , vol.7 , pp. 488-494
    • Gould, A.1
  • 53
    • 65549123471 scopus 로고    scopus 로고
    • HDAC2 negatively regulates memory formation and synaptic plasticity
    • Guan J.S., et al. HDAC2 negatively regulates memory formation and synaptic plasticity. Nature 2009, 459:55-60.
    • (2009) Nature , vol.459 , pp. 55-60
    • Guan, J.S.1
  • 54
    • 34547838109 scopus 로고    scopus 로고
    • Cell fate specification in the mammalian telencephalon
    • Guillemot F. Cell fate specification in the mammalian telencephalon. Prog. Neurobiol. 2007, 83:37-52.
    • (2007) Prog. Neurobiol. , vol.83 , pp. 37-52
    • Guillemot, F.1
  • 55
    • 3242788185 scopus 로고    scopus 로고
    • Mood stabilizer valproate promotes ERK pathway-dependent cortical neuronal growth and neurogenesis
    • Hao Y., et al. Mood stabilizer valproate promotes ERK pathway-dependent cortical neuronal growth and neurogenesis. J. Neurosci. 2004, 24:6590-6599.
    • (2004) J. Neurosci. , vol.24 , pp. 6590-6599
    • Hao, Y.1
  • 56
    • 66249086574 scopus 로고    scopus 로고
    • Interruption of beta-catenin signaling reduces neurogenesis in Alzheimer's disease
    • He P., Shen Y. Interruption of beta-catenin signaling reduces neurogenesis in Alzheimer's disease. J. Neurosci. 2009, 29:6545-6557.
    • (2009) J. Neurosci. , vol.29 , pp. 6545-6557
    • He, P.1    Shen, Y.2
  • 57
    • 60649118528 scopus 로고    scopus 로고
    • Inhibition of adult hippocampal neurogenesis disrupts contextual learning but spares spatial working memory, long-term conditional rule retention and spatial reversal
    • Hernandez-Rabaza V., et al. Inhibition of adult hippocampal neurogenesis disrupts contextual learning but spares spatial working memory, long-term conditional rule retention and spatial reversal. Neuroscience 2009, 159:59-68.
    • (2009) Neuroscience , vol.159 , pp. 59-68
    • Hernandez-Rabaza, V.1
  • 58
    • 70349438821 scopus 로고    scopus 로고
    • Two factor reprogramming of human neural stem cells into pluripotency
    • Hester M.E., et al. Two factor reprogramming of human neural stem cells into pluripotency. PLoS One 2009, e7044:4.
    • (2009) PLoS One , vol.7044 e , pp. 4
    • Hester, M.E.1
  • 59
    • 36949037305 scopus 로고    scopus 로고
    • Behavioral effects of chronic fluoxetine in BALB/cJ mice do not require adult hippocampal neurogenesis or the serotonin 1A receptor
    • Holick K.A., et al. Behavioral effects of chronic fluoxetine in BALB/cJ mice do not require adult hippocampal neurogenesis or the serotonin 1A receptor. Neuropsychopharmacology 2008, 33:406-417.
    • (2008) Neuropsychopharmacology , vol.33 , pp. 406-417
    • Holick, K.A.1
  • 60
    • 9344252804 scopus 로고    scopus 로고
    • Histone deacetylase inhibition-mediated neuronal differentiation of multipotent adult neural progenitor cells
    • Hsieh J., et al. Histone deacetylase inhibition-mediated neuronal differentiation of multipotent adult neural progenitor cells. Proc. Natl. Acad. Sci. U. S. A. 2004, 101:16659-16664.
    • (2004) Proc. Natl. Acad. Sci. U. S. A. , vol.101 , pp. 16659-16664
    • Hsieh, J.1
  • 61
    • 52949147794 scopus 로고    scopus 로고
    • Roles of continuous neurogenesis in the structural and functional integrity of the adult forebrain
    • Imayoshi I., et al. Roles of continuous neurogenesis in the structural and functional integrity of the adult forebrain. Nat. Neurosci. 2008, 11:1153-1161.
    • (2008) Nat. Neurosci. , vol.11 , pp. 1153-1161
    • Imayoshi, I.1
  • 62
    • 63849324022 scopus 로고    scopus 로고
    • Continuous neurogenesis in the adult brain
    • Imayoshi I., et al. Continuous neurogenesis in the adult brain. Dev. Growth Differ. 2009, 51:379-386.
    • (2009) Dev. Growth Differ. , vol.51 , pp. 379-386
    • Imayoshi, I.1
  • 63
    • 0037372003 scopus 로고    scopus 로고
    • Epigenetic regulation of gene expression: how the genome integrates intrinsic and environmental signals
    • Jaenisch R., Bird A. Epigenetic regulation of gene expression: how the genome integrates intrinsic and environmental signals. Nat. Genet. 2003, 33(Suppl.):245-254.
    • (2003) Nat. Genet. , vol.33 , Issue.SUPPL. , pp. 245-254
    • Jaenisch, R.1    Bird, A.2
  • 64
    • 67649386567 scopus 로고    scopus 로고
    • GABA-cAMP response element-binding protein signaling regulates maturation and survival of newly generated neurons in the adult hippocampus
    • Jagasia R., et al. GABA-cAMP response element-binding protein signaling regulates maturation and survival of newly generated neurons in the adult hippocampus. J. Neurosci. 2009, 29:7966-7977.
    • (2009) J. Neurosci. , vol.29 , pp. 7966-7977
    • Jagasia, R.1
  • 65
    • 67649580312 scopus 로고    scopus 로고
    • New hippocampal neurons are not obligatory for memory formation; cyclin D2 knockout mice with no adult brain neurogenesis show learning
    • Jaholkowski P., et al. New hippocampal neurons are not obligatory for memory formation; cyclin D2 knockout mice with no adult brain neurogenesis show learning. Learn. Mem. 2009, 16:439-451.
    • (2009) Learn. Mem. , vol.16 , pp. 439-451
    • Jaholkowski, P.1
  • 66
    • 0035839136 scopus 로고    scopus 로고
    • Translating the histone code
    • Jenuwein T., Allis C.D. Translating the histone code. Science 2001, 293:1074-1080.
    • (2001) Science , vol.293 , pp. 1074-1080
    • Jenuwein, T.1    Allis, C.D.2
  • 67
    • 34249779216 scopus 로고    scopus 로고
    • Epigenetic modulation of seizure-induced neurogenesis and cognitive decline
    • Jessberger S., et al. Epigenetic modulation of seizure-induced neurogenesis and cognitive decline. J. Neurosci. 2007, 27:5967-5975.
    • (2007) J. Neurosci. , vol.27 , pp. 5967-5975
    • Jessberger, S.1
  • 68
    • 59649095732 scopus 로고    scopus 로고
    • Dentate gyrus-specific knockdown of adult neurogenesis impairs spatial and object recognition memory in adult rats
    • Jessberger S., et al. Dentate gyrus-specific knockdown of adult neurogenesis impairs spatial and object recognition memory in adult rats. Learn. Mem. 2009, 16:147-154.
    • (2009) Learn. Mem. , vol.16 , pp. 147-154
    • Jessberger, S.1
  • 69
    • 70350120731 scopus 로고    scopus 로고
    • Making a neuron: Cdk5 in embryonic and adult neurogenesis
    • Jessberger S., et al. Making a neuron: Cdk5 in embryonic and adult neurogenesis. Trends Neurosci. 2009, 32:575-582.
    • (2009) Trends Neurosci. , vol.32 , pp. 575-582
    • Jessberger, S.1
  • 70
    • 0037015059 scopus 로고    scopus 로고
    • Vascular endothelial growth factor (VEGF) stimulates neurogenesis in vitro and in vivo
    • Jin K., et al. Vascular endothelial growth factor (VEGF) stimulates neurogenesis in vitro and in vivo. Proc. Natl. Acad. Sci. U. S. A. 2002, 99:11946-11950.
    • (2002) Proc. Natl. Acad. Sci. U. S. A. , vol.99 , pp. 11946-11950
    • Jin, K.1
  • 71
    • 0037373179 scopus 로고    scopus 로고
    • Cerebral neurogenesis is induced by intranasal administration of growth factors
    • Jin K., et al. Cerebral neurogenesis is induced by intranasal administration of growth factors. Ann. Neurol. 2003, 53:405-409.
    • (2003) Ann. Neurol. , vol.53 , pp. 405-409
    • Jin, K.1
  • 72
    • 4444269849 scopus 로고    scopus 로고
    • Enhanced neurogenesis in Alzheimer's disease transgenic (PDGF-APPSw,Ind) mice
    • Jin K., et al. Enhanced neurogenesis in Alzheimer's disease transgenic (PDGF-APPSw,Ind) mice. Proc. Natl. Acad. Sci. U. S. A. 2004, 101:13363-13367.
    • (2004) Proc. Natl. Acad. Sci. U. S. A. , vol.101 , pp. 13363-13367
    • Jin, K.1
  • 73
    • 0346458659 scopus 로고    scopus 로고
    • Increased hippocampal neurogenesis in Alzheimer's disease
    • Jin K., et al. Increased hippocampal neurogenesis in Alzheimer's disease. Proc. Natl. Acad. Sci. U. S. A. 2004, 101:343-347.
    • (2004) Proc. Natl. Acad. Sci. U. S. A. , vol.101 , pp. 343-347
    • Jin, K.1
  • 74
    • 33646551422 scopus 로고    scopus 로고
    • Alzheimer's disease drugs promote neurogenesis
    • Jin K., et al. Alzheimer's disease drugs promote neurogenesis. Brain Res. 2006, 1085:183-188.
    • (2006) Brain Res. , vol.1085 , pp. 183-188
    • Jin, K.1
  • 75
    • 41949136533 scopus 로고    scopus 로고
    • GADD45A does not promote DNA demethylation
    • Jin S.G., et al. GADD45A does not promote DNA demethylation. PLoS Genet. 2008, 4:e1000013.
    • (2008) PLoS Genet. , vol.4
    • Jin, S.G.1
  • 76
    • 66549101396 scopus 로고    scopus 로고
    • Cell-intrinsic signals that regulate adult neurogenesis in vivo: insights from inducible approaches
    • Johnson M.A., et al. Cell-intrinsic signals that regulate adult neurogenesis in vivo: insights from inducible approaches. BMB Rep. 2009, 42:245-259.
    • (2009) BMB Rep. , vol.42 , pp. 245-259
    • Johnson, M.A.1
  • 77
    • 36749082147 scopus 로고    scopus 로고
    • Base excision DNA repair defect in Gadd45a-deficient cells
    • Jung H.J., et al. Base excision DNA repair defect in Gadd45a-deficient cells. Oncogene 2007, 26:7517-7525.
    • (2007) Oncogene , vol.26 , pp. 7517-7525
    • Jung, H.J.1
  • 78
    • 0034636554 scopus 로고    scopus 로고
    • ATF-2 has intrinsic histone acetyltransferase activity which is modulated by phosphorylation
    • Kawasaki H., et al. ATF-2 has intrinsic histone acetyltransferase activity which is modulated by phosphorylation. Nature 2000, 405:195-200.
    • (2000) Nature , vol.405 , pp. 195-200
    • Kawasaki, H.1
  • 79
    • 41749113342 scopus 로고    scopus 로고
    • The contribution of failing adult hippocampal neurogenesis to psychiatric disorders
    • Kempermann G., et al. The contribution of failing adult hippocampal neurogenesis to psychiatric disorders. Curr. Opin. Psychiatry 2008, 21:290-295.
    • (2008) Curr. Opin. Psychiatry , vol.21 , pp. 290-295
    • Kempermann, G.1
  • 80
    • 34548537573 scopus 로고    scopus 로고
    • A microRNA feedback circuit in midbrain dopamine neurons
    • Kim J., et al. A microRNA feedback circuit in midbrain dopamine neurons. Science 2007, 317:1220-1224.
    • (2007) Science , vol.317 , pp. 1220-1224
    • Kim, J.1
  • 81
    • 48349095740 scopus 로고    scopus 로고
    • Pluripotent stem cells induced from adult neural stem cells by reprogramming with two factors
    • Kim J.B., et al. Pluripotent stem cells induced from adult neural stem cells by reprogramming with two factors. Nature 2008, 454:646-650.
    • (2008) Nature , vol.454 , pp. 646-650
    • Kim, J.B.1
  • 82
    • 70349687407 scopus 로고    scopus 로고
    • Direct reprogramming of human neural stem cells by OCT4
    • Kim J.B., et al. Direct reprogramming of human neural stem cells by OCT4. Nature 2009, 461:649-653.
    • (2009) Nature , vol.461 , pp. 649-653
    • Kim, J.B.1
  • 83
    • 59349108302 scopus 로고    scopus 로고
    • Oct4-induced pluripotency in adult neural stem cells
    • Kim J.B., et al. Oct4-induced pluripotency in adult neural stem cells. Cell 2009, 136:411-419.
    • (2009) Cell , vol.136 , pp. 411-419
    • Kim, J.B.1
  • 84
    • 32344450824 scopus 로고    scopus 로고
    • Genomic DNA methylation: the mark and its mediators
    • Klose R.J., Bird A.P. Genomic DNA methylation: the mark and its mediators. Trends Biochem. Sci. 2006, 31:89-97.
    • (2006) Trends Biochem. Sci. , vol.31 , pp. 89-97
    • Klose, R.J.1    Bird, A.P.2
  • 85
    • 64949111526 scopus 로고    scopus 로고
    • Effect of ablated hippocampal neurogenesis on the formation and extinction of contextual fear memory
    • Ko H.G., et al. Effect of ablated hippocampal neurogenesis on the formation and extinction of contextual fear memory. Mol. Brain 2009, 2:1.
    • (2009) Mol. Brain , vol.2 , pp. 1
    • Ko, H.G.1
  • 86
    • 63149107984 scopus 로고    scopus 로고
    • Targeting the hippocampal mossy fiber synapse for the treatment of psychiatric disorders
    • Kobayashi K. Targeting the hippocampal mossy fiber synapse for the treatment of psychiatric disorders. Mol. Neurobiol. 2009, 39:24-36.
    • (2009) Mol. Neurobiol. , vol.39 , pp. 24-36
    • Kobayashi, K.1
  • 87
    • 56649117538 scopus 로고    scopus 로고
    • Epigenetic regulation of neural cell differentiation plasticity in the adult mammalian brain
    • Kohyama J., et al. Epigenetic regulation of neural cell differentiation plasticity in the adult mammalian brain. Proc. Natl. Acad. Sci. U. S. A. 2008, 105:18012-18017.
    • (2008) Proc. Natl. Acad. Sci. U. S. A. , vol.105 , pp. 18012-18017
    • Kohyama, J.1
  • 88
    • 33751254116 scopus 로고    scopus 로고
    • The neuronal microRNA system
    • Kosik K.S. The neuronal microRNA system. Nat. Rev. Neurosci. 2006, 7:911-920.
    • (2006) Nat. Rev. Neurosci. , vol.7 , pp. 911-920
    • Kosik, K.S.1
  • 89
    • 24644437266 scopus 로고    scopus 로고
    • The elegance of the microRNAs: a neuronal perspective
    • Kosik K.S., Krichevsky A.M. The elegance of the microRNAs: a neuronal perspective. Neuron 2005, 47:779-782.
    • (2005) Neuron , vol.47 , pp. 779-782
    • Kosik, K.S.1    Krichevsky, A.M.2
  • 90
    • 55749095699 scopus 로고    scopus 로고
    • Hippocampal neurogenesis and neural stem cells in temporal lobe epilepsy
    • Kuruba R., et al. Hippocampal neurogenesis and neural stem cells in temporal lobe epilepsy. Epilepsy Behav. 2009, 14(Suppl 1):65-73.
    • (2009) Epilepsy Behav. , vol.14 , Issue.1 SUPPL , pp. 65-73
    • Kuruba, R.1
  • 91
    • 1642603947 scopus 로고    scopus 로고
    • A small modulatory dsRNA specifies the fate of adult neural stem cells
    • Kuwabara T., et al. A small modulatory dsRNA specifies the fate of adult neural stem cells. Cell 2004, 116:779-793.
    • (2004) Cell , vol.116 , pp. 779-793
    • Kuwabara, T.1
  • 92
    • 0037197803 scopus 로고    scopus 로고
    • Identification of tissue-specific microRNAs from mouse
    • Lagos-Quintana M., et al. Identification of tissue-specific microRNAs from mouse. Curr. Biol. 2002, 12:735-739.
    • (2002) Curr. Biol. , vol.12 , pp. 735-739
    • Lagos-Quintana, M.1
  • 93
    • 34247571490 scopus 로고    scopus 로고
    • Nrsf silencing induces molecular and subcellular changes linked to neuronal plasticity
    • Lepagnol-Bestel A.M., et al. Nrsf silencing induces molecular and subcellular changes linked to neuronal plasticity. Neuroreport 2007, 18:441-446.
    • (2007) Neuroreport , vol.18 , pp. 441-446
    • Lepagnol-Bestel, A.M.1
  • 94
    • 34447249019 scopus 로고    scopus 로고
    • An essential switch in subunit composition of a chromatin remodeling complex during neural development
    • Lessard J., et al. An essential switch in subunit composition of a chromatin remodeling complex during neural development. Neuron 2007, 55:201-215.
    • (2007) Neuron , vol.55 , pp. 201-215
    • Lessard, J.1
  • 95
    • 77449092328 scopus 로고    scopus 로고
    • Structural plasticity and hippocampal function
    • C1-3
    • Leuner B., Gould E. Structural plasticity and hippocampal function. Annu Rev Psychol. 2010, 61:111-140. C1-3.
    • (2010) Annu Rev Psychol. , vol.61 , pp. 111-140
    • Leuner, B.1    Gould, E.2
  • 96
    • 33744920106 scopus 로고    scopus 로고
    • Evidence that DNA (cytosine-5) methyltransferase regulates synaptic plasticity in the hippocampus
    • Levenson J.M., et al. Evidence that DNA (cytosine-5) methyltransferase regulates synaptic plasticity in the hippocampus. J. Biol. Chem. 2006, 281:15763-15773.
    • (2006) J. Biol. Chem. , vol.281 , pp. 15763-15773
    • Levenson, J.M.1
  • 97
    • 37549013706 scopus 로고    scopus 로고
    • Failure of neuronal maturation in Alzheimer disease dentate gyrus
    • Li B., et al. Failure of neuronal maturation in Alzheimer disease dentate gyrus. J. Neuropathol. Exp. Neurol. 2008, 67:78-84.
    • (2008) J. Neuropathol. Exp. Neurol. , vol.67 , pp. 78-84
    • Li, B.1
  • 98
    • 55549108710 scopus 로고    scopus 로고
    • Epigenetic regulation of the stem cell mitogen Fgf-2 by Mbd1 in adult neural stem/progenitor cells
    • Li X., et al. Epigenetic regulation of the stem cell mitogen Fgf-2 by Mbd1 in adult neural stem/progenitor cells. J. Biol. Chem. 2008, 283:27644-27652.
    • (2008) J. Biol. Chem. , vol.283 , pp. 27644-27652
    • Li, X.1
  • 99
    • 25844432119 scopus 로고    scopus 로고
    • Wnt signalling regulates adult hippocampal neurogenesis
    • Lie D.C., et al. Wnt signalling regulates adult hippocampal neurogenesis. Nature 2005, 437:1370-1375.
    • (2005) Nature , vol.437 , pp. 1370-1375
    • Lie, D.C.1
  • 100
    • 13944282215 scopus 로고    scopus 로고
    • Microarray analysis shows that some microRNAs downregulate large numbers of target mRNAs
    • Lim L.P., et al. Microarray analysis shows that some microRNAs downregulate large numbers of target mRNAs. Nature 2005, 433:769-773.
    • (2005) Nature , vol.433 , pp. 769-773
    • Lim, L.P.1
  • 101
    • 30044448566 scopus 로고    scopus 로고
    • In vivo transcriptional profile analysis reveals RNA splicing and chromatin remodeling as prominent processes for adult neurogenesis
    • Lim D.A., et al. In vivo transcriptional profile analysis reveals RNA splicing and chromatin remodeling as prominent processes for adult neurogenesis. Mol. Cell. Neurosci. 2006, 31:131-148.
    • (2006) Mol. Cell. Neurosci. , vol.31 , pp. 131-148
    • Lim, D.A.1
  • 102
    • 63649125648 scopus 로고    scopus 로고
    • Chromatin remodelling factor Mll1 is essential for neurogenesis from postnatal neural stem cells
    • Lim D.A., et al. Chromatin remodelling factor Mll1 is essential for neurogenesis from postnatal neural stem cells. Nature 2009, 458:529-533.
    • (2009) Nature , vol.458 , pp. 529-533
    • Lim, D.A.1
  • 103
    • 24644492005 scopus 로고    scopus 로고
    • Nonsynaptic GABA signaling in postnatal subventricular zone controls proliferation of GFAP-expressing progenitors
    • Liu X., et al. Nonsynaptic GABA signaling in postnatal subventricular zone controls proliferation of GFAP-expressing progenitors. Nat. Neurosci. 2005, 8:1179-1187.
    • (2005) Nat. Neurosci. , vol.8 , pp. 1179-1187
    • Liu, X.1
  • 104
    • 34347351990 scopus 로고    scopus 로고
    • Adult neurogenesis in mesial temporal lobe epilepsy: a review of recent animal and human studies
    • Liu Y.W., et al. Adult neurogenesis in mesial temporal lobe epilepsy: a review of recent animal and human studies. Curr. Pharm. Biotechnol. 2007, 8:187-194.
    • (2007) Curr. Pharm. Biotechnol. , vol.8 , pp. 187-194
    • Liu, Y.W.1
  • 105
    • 56349140240 scopus 로고    scopus 로고
    • Repeated clomipramine treatment reversed the inhibition of cell proliferation in adult hippocampus induced by chronic unpredictable stress
    • Liu Q., et al. Repeated clomipramine treatment reversed the inhibition of cell proliferation in adult hippocampus induced by chronic unpredictable stress. Pharmacogenomics J. 2008, 8:375-383.
    • (2008) Pharmacogenomics J. , vol.8 , pp. 375-383
    • Liu, Q.1
  • 106
    • 56749164977 scopus 로고    scopus 로고
    • Doublecortin expression in the normal and epileptic adult human brain
    • Liu Y.W., et al. Doublecortin expression in the normal and epileptic adult human brain. Eur. J. Neurosci. 2008, 28:2254-2265.
    • (2008) Eur. J. Neurosci. , vol.28 , pp. 2254-2265
    • Liu, Y.W.1
  • 108
    • 60749094831 scopus 로고    scopus 로고
    • Neuronal activity-induced Gadd45b promotes epigenetic DNA demethylation and adult neurogenesis
    • Ma D.K., et al. Neuronal activity-induced Gadd45b promotes epigenetic DNA demethylation and adult neurogenesis. Science 2009, 323:1074-1077.
    • (2009) Science , vol.323 , pp. 1074-1077
    • Ma, D.K.1
  • 109
    • 34547212309 scopus 로고    scopus 로고
    • The MicroRNA miR-124 promotes neuronal differentiation by triggering brain-specific alternative pre-mRNA splicing
    • Makeyev E.V., et al. The MicroRNA miR-124 promotes neuronal differentiation by triggering brain-specific alternative pre-mRNA splicing. Mol. Cell 2007, 27:435-448.
    • (2007) Mol. Cell , vol.27 , pp. 435-448
    • Makeyev, E.V.1
  • 110
    • 0034671366 scopus 로고    scopus 로고
    • Chronic antidepressant treatment increases neurogenesis in adult rat hippocampus
    • Malberg J.E., et al. Chronic antidepressant treatment increases neurogenesis in adult rat hippocampus. J. Neurosci. 2000, 20:9104-9110.
    • (2000) J. Neurosci. , vol.20 , pp. 9104-9110
    • Malberg, J.E.1
  • 111
    • 36048970985 scopus 로고    scopus 로고
    • Magnetic resonance spectroscopy identifies neural progenitor cells in the live human brain
    • Manganas L.N., et al. Magnetic resonance spectroscopy identifies neural progenitor cells in the live human brain. Science 2007, 318:980-985.
    • (2007) Science , vol.318 , pp. 980-985
    • Manganas, L.N.1
  • 112
    • 0034667299 scopus 로고    scopus 로고
    • Clinical and preclinical evidence for the neurotrophic effects of mood stabilizers: implications for the pathophysiology and treatment of manic-depressive illness
    • Manji H.K., et al. Clinical and preclinical evidence for the neurotrophic effects of mood stabilizers: implications for the pathophysiology and treatment of manic-depressive illness. Biol. Psychiatry 2000, 48:740-754.
    • (2000) Biol. Psychiatry , vol.48 , pp. 740-754
    • Manji, H.K.1
  • 113
    • 62149083806 scopus 로고    scopus 로고
    • Disrupted in schizophrenia 1 regulates neuronal progenitor proliferation via modulation of GSK3beta/beta-catenin signaling
    • Mao Y., et al. Disrupted in schizophrenia 1 regulates neuronal progenitor proliferation via modulation of GSK3beta/beta-catenin signaling. Cell 2009, 136:1017-1031.
    • (2009) Cell , vol.136 , pp. 1017-1031
    • Mao, Y.1
  • 114
    • 70349445082 scopus 로고    scopus 로고
    • Transcriptional signature and memory retention of human-induced pluripotent stem cells
    • Marchetto M.C., et al. Transcriptional signature and memory retention of human-induced pluripotent stem cells. PLoS One 2009, e7076:4.
    • (2009) PLoS One , vol.7076 e , pp. 4
    • Marchetto, M.C.1
  • 115
    • 15944402920 scopus 로고    scopus 로고
    • Small regulatory RNAs in mammals
    • Spec No 1
    • Mattick J.S., Makunin I.V. Small regulatory RNAs in mammals. Hum. Mol. Genet. 2005, 14(Spec No 1):R121-R132.
    • (2005) Hum. Mol. Genet. , vol.14
    • Mattick, J.S.1    Makunin, I.V.2
  • 116
    • 57049151436 scopus 로고    scopus 로고
    • Epigenetic principles and mechanisms underlying nervous system functions in health and disease
    • Mehler M.F. Epigenetic principles and mechanisms underlying nervous system functions in health and disease. Prog. Neurobiol. 2008, 86:305-341.
    • (2008) Prog. Neurobiol. , vol.86 , pp. 305-341
    • Mehler, M.F.1
  • 117
    • 34249724360 scopus 로고    scopus 로고
    • Noncoding RNAs and RNA editing in brain development, functional diversification, and neurological disease
    • Mehler M.F., Mattick J.S. Noncoding RNAs and RNA editing in brain development, functional diversification, and neurological disease. Physiol. Rev. 2007, 87:799-823.
    • (2007) Physiol. Rev. , vol.87 , pp. 799-823
    • Mehler, M.F.1    Mattick, J.S.2
  • 118
    • 40449123137 scopus 로고    scopus 로고
    • Cyclical DNA methylation of a transcriptionally active promoter
    • Metivier R., et al. Cyclical DNA methylation of a transcriptionally active promoter. Nature 2008, 452:45-50.
    • (2008) Nature , vol.452 , pp. 45-50
    • Metivier, R.1
  • 119
    • 0034702026 scopus 로고    scopus 로고
    • Disruption of two novel genes by a translocation co-segregating with schizophrenia
    • Millar J.K., et al. Disruption of two novel genes by a translocation co-segregating with schizophrenia. Hum. Mol. Genet. 2000, 9:1415-1423.
    • (2000) Hum. Mol. Genet. , vol.9 , pp. 1415-1423
    • Millar, J.K.1
  • 120
    • 23244458855 scopus 로고    scopus 로고
    • Adult neurogenesis in the mammalian central nervous system
    • Ming G.L., Song H. Adult neurogenesis in the mammalian central nervous system. Annu. Rev. Neurosci. 2005, 28:223-250.
    • (2005) Annu. Rev. Neurosci. , vol.28 , pp. 223-250
    • Ming, G.L.1    Song, H.2
  • 121
    • 0042622356 scopus 로고    scopus 로고
    • Disrupted-in-schizophrenia 1, a candidate gene for schizophrenia, participates in neurite outgrowth
    • Miyoshi K., et al. Disrupted-in-schizophrenia 1, a candidate gene for schizophrenia, participates in neurite outgrowth. Mol. Psychiatry 2003, 8:685-694.
    • (2003) Mol. Psychiatry , vol.8 , pp. 685-694
    • Miyoshi, K.1
  • 122
    • 0242667922 scopus 로고    scopus 로고
    • Bmi-1 dependence distinguishes neural stem cell self-renewal from progenitor proliferation
    • Molofsky A.V., et al. Bmi-1 dependence distinguishes neural stem cell self-renewal from progenitor proliferation. Nature 2003, 425:962-967.
    • (2003) Nature , vol.425 , pp. 962-967
    • Molofsky, A.V.1
  • 123
    • 66049101024 scopus 로고    scopus 로고
    • Histone deacetylases 1 and 2 control the progression of neural precursors to neurons during brain development
    • Montgomery R.L., et al. Histone deacetylases 1 and 2 control the progression of neural precursors to neurons during brain development. Proc. Natl. Acad. Sci. U. S. A. 2009, 106:7876-7881.
    • (2009) Proc. Natl. Acad. Sci. U. S. A. , vol.106 , pp. 7876-7881
    • Montgomery, R.L.1
  • 124
    • 0037766786 scopus 로고    scopus 로고
    • DISC1 (disrupted-in-schizophrenia 1) is a centrosome-associated protein that interacts with MAP1A, MIPT3, ATF4/5 and NUDEL: regulation and loss of interaction with mutation
    • Morris J.A., et al. DISC1 (disrupted-in-schizophrenia 1) is a centrosome-associated protein that interacts with MAP1A, MIPT3, ATF4/5 and NUDEL: regulation and loss of interaction with mutation. Hum. Mol. Genet. 2003, 12:1591-1608.
    • (2003) Hum. Mol. Genet. , vol.12 , pp. 1591-1608
    • Morris, J.A.1
  • 125
    • 39149144034 scopus 로고    scopus 로고
    • Stem cells and niches: mechanisms that promote stem cell maintenance throughout life
    • Morrison S.J., Spradling A.C. Stem cells and niches: mechanisms that promote stem cell maintenance throughout life. Cell 2008, 132:598-611.
    • (2008) Cell , vol.132 , pp. 598-611
    • Morrison, S.J.1    Spradling, A.C.2
  • 126
    • 62849106337 scopus 로고    scopus 로고
    • Beta-catenin hits chromatin: regulation of Wnt target gene activation
    • Mosimann C., et al. Beta-catenin hits chromatin: regulation of Wnt target gene activation. Nat. Rev. Mol. Cell. Biol. 2009, 10:276-286.
    • (2009) Nat. Rev. Mol. Cell. Biol. , vol.10 , pp. 276-286
    • Mosimann, C.1
  • 127
    • 0033574767 scopus 로고    scopus 로고
    • Synergistic signaling in fetal brain by STAT3-Smad1 complex bridged by p300
    • Nakashima K., et al. Synergistic signaling in fetal brain by STAT3-Smad1 complex bridged by p300. Science 1999, 284:479-482.
    • (1999) Science , vol.284 , pp. 479-482
    • Nakashima, K.1
  • 128
    • 69449084425 scopus 로고    scopus 로고
    • The Alzheimer's disease drug memantine increases the number of radial glia-like progenitor cells in adult hippocampus
    • Namba T., et al. The Alzheimer's disease drug memantine increases the number of radial glia-like progenitor cells in adult hippocampus. Glia 2009, 57:1082-1090.
    • (2009) Glia , vol.57 , pp. 1082-1090
    • Namba, T.1
  • 129
    • 4143141064 scopus 로고    scopus 로고
    • Developmental stage dependent regulation of DNA methylation and chromatin modification in a immature astrocyte specific gene promoter
    • Namihira M., et al. Developmental stage dependent regulation of DNA methylation and chromatin modification in a immature astrocyte specific gene promoter. FEBS Lett. 2004, 572:184-188.
    • (2004) FEBS Lett. , vol.572 , pp. 184-188
    • Namihira, M.1
  • 130
    • 59649112849 scopus 로고    scopus 로고
    • Committed neuronal precursors confer astrocytic potential on residual neural precursor cells
    • Namihira M., et al. Committed neuronal precursors confer astrocytic potential on residual neural precursor cells. Dev. Cell 2009, 16:245-255.
    • (2009) Dev. Cell , vol.16 , pp. 245-255
    • Namihira, M.1
  • 131
    • 33746217425 scopus 로고    scopus 로고
    • Chromatin remodeling: a novel mechanism of psychotropic drug action
    • Newton S.S., Duman R.S. Chromatin remodeling: a novel mechanism of psychotropic drug action. Mol. Pharmacol. 2006, 70:440-443.
    • (2006) Mol. Pharmacol. , vol.70 , pp. 440-443
    • Newton, S.S.1    Duman, R.S.2
  • 132
    • 74849125320 scopus 로고    scopus 로고
    • Reduction of adult hippocampal neurogenesis confers vulnerability in an animal model of cocaine addiction
    • Noonan, M. A., et al., 2010. Reduction of adult hippocampal neurogenesis confers vulnerability in an animal model of cocaine addiction. J. Neurosci. 30, 304-315.
    • (2010) J. Neurosci. , vol.30 , pp. 304-315
    • Noonan, M.A.1
  • 133
    • 52149108919 scopus 로고    scopus 로고
    • S-Nitrosylation of histone deacetylase 2 induces chromatin remodelling in neurons
    • Nott A., et al. S-Nitrosylation of histone deacetylase 2 induces chromatin remodelling in neurons. Nature 2008, 455:411-415.
    • (2008) Nature , vol.455 , pp. 411-415
    • Nott, A.1
  • 134
    • 67650741664 scopus 로고    scopus 로고
    • Cell types to order: temporal specification of CNS stem cells
    • Okano H., Temple S. Cell types to order: temporal specification of CNS stem cells. Curr. Opin. Neurobiol. 2009, 19:112-119.
    • (2009) Curr. Opin. Neurobiol. , vol.19 , pp. 112-119
    • Okano, H.1    Temple, S.2
  • 135
    • 45449114804 scopus 로고    scopus 로고
    • The colorful history of active DNA demethylation
    • Ooi S.K., Bestor T.H. The colorful history of active DNA demethylation. Cell 2008, 133:1145-1148.
    • (2008) Cell , vol.133 , pp. 1145-1148
    • Ooi, S.K.1    Bestor, T.H.2
  • 136
    • 0034597430 scopus 로고    scopus 로고
    • Vascular niche for adult hippocampal neurogenesis
    • Palmer T.D., et al. Vascular niche for adult hippocampal neurogenesis. J. Comp. Neurol. 2000, 425:479-494.
    • (2000) J. Comp. Neurol. , vol.425 , pp. 479-494
    • Palmer, T.D.1
  • 137
    • 35748953722 scopus 로고    scopus 로고
    • Is neurogenesis reparative after status epilepticusŽ
    • Parent J.M., et al. Is neurogenesis reparative after status epilepticus?. Epilepsia 2007, 48(Suppl 8):69-71.
    • (2007) Epilepsia , vol.48 , Issue.8 SUPPL. , pp. 69-71
    • Parent, J.M.1
  • 138
    • 38049187707 scopus 로고    scopus 로고
    • Reprogramming of human somatic cells to pluripotency with defined factors
    • Park I.H., et al. Reprogramming of human somatic cells to pluripotency with defined factors. Nature 2008, 451:141-146.
    • (2008) Nature , vol.451 , pp. 141-146
    • Park, I.H.1
  • 139
    • 34247856025 scopus 로고    scopus 로고
    • Antidepressant-induced neurogenesis in the hippocampus of adult nonhuman primates
    • Perera T.D., et al. Antidepressant-induced neurogenesis in the hippocampus of adult nonhuman primates. J. Neurosci. 2007, 27:4894-4901.
    • (2007) J. Neurosci. , vol.27 , pp. 4894-4901
    • Perera, T.D.1
  • 140
    • 47549107048 scopus 로고    scopus 로고
    • Cognitive role of neurogenesis in depression and antidepressant treatment
    • Perera T.D., et al. Cognitive role of neurogenesis in depression and antidepressant treatment. Neuroscientist 2008, 14:326-338.
    • (2008) Neuroscientist , vol.14 , pp. 326-338
    • Perera, T.D.1
  • 141
    • 57649196594 scopus 로고    scopus 로고
    • DNA demethylation in zebrafish involves the coupling of a deaminase, a glycosylase, and gadd45
    • Rai K., et al. DNA demethylation in zebrafish involves the coupling of a deaminase, a glycosylase, and gadd45. Cell 2008, 135:1201-1212.
    • (2008) Cell , vol.135 , pp. 1201-1212
    • Rai, K.1
  • 142
    • 33646377899 scopus 로고    scopus 로고
    • Neural stem cell proliferation is decreased in schizophrenia, but not in depression
    • Reif A., et al. Neural stem cell proliferation is decreased in schizophrenia, but not in depression. Mol. Psychiatry 2006, 11:514-522.
    • (2006) Mol. Psychiatry , vol.11 , pp. 514-522
    • Reif, A.1
  • 143
    • 35648934049 scopus 로고    scopus 로고
    • Histone deacetylase 5 epigenetically controls behavioral adaptations to chronic emotional stimuli
    • Renthal W., et al. Histone deacetylase 5 epigenetically controls behavioral adaptations to chronic emotional stimuli. Neuron 2007, 56:517-529.
    • (2007) Neuron , vol.56 , pp. 517-529
    • Renthal, W.1
  • 144
    • 48149096013 scopus 로고    scopus 로고
    • Epigenetic mechanisms in drug addiction
    • Renthal W., Nestler E.J. Epigenetic mechanisms in drug addiction. Trends Mol. Med. 2008, 14:341-350.
    • (2008) Trends Mol. Med. , vol.14 , pp. 341-350
    • Renthal, W.1    Nestler, E.J.2
  • 145
    • 70349687254 scopus 로고    scopus 로고
    • Adult hippocampal neurogenesis is involved in anxiety-related behaviors
    • Revest J.M., et al. Adult hippocampal neurogenesis is involved in anxiety-related behaviors. Mol. Psychiatry 2009, 14:959-967.
    • (2009) Mol. Psychiatry , vol.14 , pp. 959-967
    • Revest, J.M.1
  • 147
    • 8844265508 scopus 로고    scopus 로고
    • Epigenetic regulation of cellular memory by the Polycomb and Trithorax group proteins
    • Ringrose L., Paro R. Epigenetic regulation of cellular memory by the Polycomb and Trithorax group proteins. Annu. Rev. Genet. 2004, 38:413-443.
    • (2004) Annu. Rev. Genet. , vol.38 , pp. 413-443
    • Ringrose, L.1    Paro, R.2
  • 148
    • 36749026287 scopus 로고    scopus 로고
    • Genomic analysis of human microRNA transcripts
    • Saini H.K., et al. Genomic analysis of human microRNA transcripts. Proc. Natl. Acad. Sci. U. S. A. 2007, 104:17719-17724.
    • (2007) Proc. Natl. Acad. Sci. U. S. A. , vol.104 , pp. 17719-17724
    • Saini, H.K.1
  • 149
    • 60849112259 scopus 로고    scopus 로고
    • Annotation of mammalian primary microRNAs
    • Saini H.K., et al. Annotation of mammalian primary microRNAs. BMC Genomics 2008, 9:564.
    • (2008) BMC Genomics , vol.9 , pp. 564
    • Saini, H.K.1
  • 150
    • 13944257674 scopus 로고    scopus 로고
    • Brain-derived neurotrophic factor and antidepressant drugs have different but coordinated effects on neuronal turnover, proliferation, and survival in the adult dentate gyrus
    • Sairanen M., et al. Brain-derived neurotrophic factor and antidepressant drugs have different but coordinated effects on neuronal turnover, proliferation, and survival in the adult dentate gyrus. J. Neurosci. 2005, 25:1089-1094.
    • (2005) J. Neurosci. , vol.25 , pp. 1089-1094
    • Sairanen, M.1
  • 151
    • 0042528720 scopus 로고    scopus 로고
    • Requirement of hippocampal neurogenesis for the behavioral effects of antidepressants
    • Santarelli L., et al. Requirement of hippocampal neurogenesis for the behavioral effects of antidepressants. Science 2003, 301:805-809.
    • (2003) Science , vol.301 , pp. 805-809
    • Santarelli, L.1
  • 152
    • 0033800486 scopus 로고    scopus 로고
    • Glucocorticoids and hippocampal atrophy in neuropsychiatric disorders
    • Sapolsky R.M. Glucocorticoids and hippocampal atrophy in neuropsychiatric disorders. Arch. Gen. Psychiatry 2000, 57:925-935.
    • (2000) Arch. Gen. Psychiatry , vol.57 , pp. 925-935
    • Sapolsky, R.M.1
  • 153
    • 3242808933 scopus 로고    scopus 로고
    • Is impaired neurogenesis relevant to the affective symptoms of depressionŽ
    • Sapolsky R.M. Is impaired neurogenesis relevant to the affective symptoms of depression?. Biol. Psychiatry 2004, 56:137-139.
    • (2004) Biol. Psychiatry , vol.56 , pp. 137-139
    • Sapolsky, R.M.1
  • 154
    • 34447261382 scopus 로고    scopus 로고
    • Cerebellar neurodegeneration in the absence of microRNAs
    • Schaefer A., et al. Cerebellar neurodegeneration in the absence of microRNAs. J. Exp. Med. 2007, 204:1553-1558.
    • (2007) J. Exp. Med. , vol.204 , pp. 1553-1558
    • Schaefer, A.1
  • 155
    • 4143127545 scopus 로고    scopus 로고
    • Direct stimulation of adult neural stem cells in vitro and neurogenesis in vivo by vascular endothelial growth factor
    • Schanzer A., et al. Direct stimulation of adult neural stem cells in vitro and neurogenesis in vivo by vascular endothelial growth factor. Brain Pathol. 2004, 14:237-248.
    • (2004) Brain Pathol. , vol.14 , pp. 237-248
    • Schanzer, A.1
  • 156
    • 33846586998 scopus 로고    scopus 로고
    • Neuroscience. Is more neurogenesis always betterŽ
    • Scharfman H.E., Hen R. Neuroscience. Is more neurogenesis always better?. Science 2007, 315:336-338.
    • (2007) Science , vol.315 , pp. 336-338
    • Scharfman, H.E.1    Hen, R.2
  • 157
    • 0037074010 scopus 로고    scopus 로고
    • Signaling network model of chromatin
    • Schreiber S.L., Bernstein B.E. Signaling network model of chromatin. Cell 2002, 111:771-778.
    • (2002) Cell , vol.111 , pp. 771-778
    • Schreiber, S.L.1    Bernstein, B.E.2
  • 158
    • 0036471609 scopus 로고    scopus 로고
    • Molecular mechanisms underlying cell fate specification in the developing telencephalon
    • Schuurmans C., Guillemot F. Molecular mechanisms underlying cell fate specification in the developing telencephalon. Curr. Opin. Neurobiol. 2002, 12:26-34.
    • (2002) Curr. Opin. Neurobiol. , vol.12 , pp. 26-34
    • Schuurmans, C.1    Guillemot, F.2
  • 159
    • 33750689875 scopus 로고    scopus 로고
    • Gene control by large noncoding RNAs
    • Shamovsky I., Nudler E. Gene control by large noncoding RNAs. Sci. STKE 2006, 2006:pe40.
    • (2006) Sci. STKE , vol.2006
    • Shamovsky, I.1    Nudler, E.2
  • 160
    • 9244234323 scopus 로고    scopus 로고
    • Schizophrenia, epigenetics and ligand-activated nuclear receptors: a framework for chromatin therapeutics
    • Sharma R.P. Schizophrenia, epigenetics and ligand-activated nuclear receptors: a framework for chromatin therapeutics. Schizophr. Res. 2005, 72:79-90.
    • (2005) Schizophr. Res. , vol.72 , pp. 79-90
    • Sharma, R.P.1
  • 161
    • 2542626091 scopus 로고    scopus 로고
    • Endothelial cells stimulate self-renewal and expand neurogenesis of neural stem cells
    • Shen Q., et al. Endothelial cells stimulate self-renewal and expand neurogenesis of neural stem cells. Science 2004, 304:1338-1340.
    • (2004) Science , vol.304 , pp. 1338-1340
    • Shen, Q.1
  • 162
    • 50849142558 scopus 로고    scopus 로고
    • Adult SVZ stem cells lie in a vascular niche: a quantitative analysis of niche cell-cell interactions
    • Shen Q., et al. Adult SVZ stem cells lie in a vascular niche: a quantitative analysis of niche cell-cell interactions. Cell Stem Cell 2008, 3:289-300.
    • (2008) Cell Stem Cell , vol.3 , pp. 289-300
    • Shen, Q.1
  • 163
    • 0034548865 scopus 로고    scopus 로고
    • Adult spinal cord stem cells generate neurons after transplantation in the adult dentate gyrus
    • Shihabuddin L.S., et al. Adult spinal cord stem cells generate neurons after transplantation in the adult dentate gyrus. J. Neurosci. 2000, 20:8727-8735.
    • (2000) J. Neurosci. , vol.20 , pp. 8727-8735
    • Shihabuddin, L.S.1
  • 164
    • 67449110898 scopus 로고    scopus 로고
    • Conditional ablation and recovery of forebrain neurogenesis in the mouse
    • Singer B.H., et al. Conditional ablation and recovery of forebrain neurogenesis in the mouse. J. Comp. Neurol. 2009, 514:567-582.
    • (2009) J. Comp. Neurol. , vol.514 , pp. 567-582
    • Singer, B.H.1
  • 165
    • 34250333455 scopus 로고    scopus 로고
    • Mecp2 deficiency leads to delayed maturation and altered gene expression in hippocampal neurons
    • Smrt R.D., et al. Mecp2 deficiency leads to delayed maturation and altered gene expression in hippocampal neurons. Neurobiol. Dis. 2007, 27:77-89.
    • (2007) Neurobiol. Dis. , vol.27 , pp. 77-89
    • Smrt, R.D.1
  • 166
    • 61349100729 scopus 로고    scopus 로고
    • Parkinson's disease patient-derived induced pluripotent stem cells free of viral reprogramming factors
    • Soldner F., et al. Parkinson's disease patient-derived induced pluripotent stem cells free of viral reprogramming factors. Cell 2009, 136:964-977.
    • (2009) Cell , vol.136 , pp. 964-977
    • Soldner, F.1
  • 167
    • 0037007647 scopus 로고    scopus 로고
    • Astroglia induce neurogenesis from adult neural stem cells
    • Song H., et al. Astroglia induce neurogenesis from adult neural stem cells. Nature 2002, 417:39-44.
    • (2002) Nature , vol.417 , pp. 39-44
    • Song, H.1
  • 168
    • 0036234835 scopus 로고    scopus 로고
    • Neural stem cells from adult hippocampus develop essential properties of functional CNS neurons
    • Song H.J., et al. Neural stem cells from adult hippocampus develop essential properties of functional CNS neurons. Nat. Neurosci. 2002, 5:438-445.
    • (2002) Nat. Neurosci. , vol.5 , pp. 438-445
    • Song, H.J.1
  • 169
    • 0034610814 scopus 로고    scopus 로고
    • The language of covalent histone modifications
    • Strahl B.D., Allis C.D. The language of covalent histone modifications. Nature 2000, 403:41-45.
    • (2000) Nature , vol.403 , pp. 41-45
    • Strahl, B.D.1    Allis, C.D.2
  • 170
    • 35848939829 scopus 로고    scopus 로고
    • In vivo fate analysis reveals the multipotent and self-renewal capacities of Sox2+ neural stem cells in the adult hippocampus
    • Suh H., et al. In vivo fate analysis reveals the multipotent and self-renewal capacities of Sox2+ neural stem cells in the adult hippocampus. Cell Stem Cell 2007, 1:515-528.
    • (2007) Cell Stem Cell , vol.1 , pp. 515-528
    • Suh, H.1
  • 171
    • 0029967893 scopus 로고    scopus 로고
    • Differentiation of adult hippocampus-derived progenitors into olfactory neurons in vivo
    • Suhonen J.O., et al. Differentiation of adult hippocampus-derived progenitors into olfactory neurons in vivo. Nature 1996, 383:624-627.
    • (1996) Nature , vol.383 , pp. 624-627
    • Suhonen, J.O.1
  • 172
    • 0035830503 scopus 로고    scopus 로고
    • Neurogenin promotes neurogenesis and inhibits glial differentiation by independent mechanisms
    • Sun Y., et al. Neurogenin promotes neurogenesis and inhibits glial differentiation by independent mechanisms. Cell 2001, 104:365-376.
    • (2001) Cell , vol.104 , pp. 365-376
    • Sun, Y.1
  • 173
    • 48049094446 scopus 로고    scopus 로고
    • Drug-dependent requirement of hippocampal neurogenesis in a model of depression and of antidepressant reversal
    • Surget A., et al. Drug-dependent requirement of hippocampal neurogenesis in a model of depression and of antidepressant reversal. Biol. Psychiatry 2008, 64:293-301.
    • (2008) Biol. Psychiatry , vol.64 , pp. 293-301
    • Surget, A.1
  • 174
    • 58149308474 scopus 로고    scopus 로고
    • Experience-dependent epigenetic modifications in the central nervous system
    • Sweatt J.D. Experience-dependent epigenetic modifications in the central nervous system. Biol. Psychiatry 2009, 65:191-197.
    • (2009) Biol. Psychiatry , vol.65 , pp. 191-197
    • Sweatt, J.D.1
  • 175
    • 33747195353 scopus 로고    scopus 로고
    • Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors
    • Takahashi K., Yamanaka S. Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors. Cell 2006, 126:663-676.
    • (2006) Cell , vol.126 , pp. 663-676
    • Takahashi, K.1    Yamanaka, S.2
  • 176
    • 36248966518 scopus 로고    scopus 로고
    • Induction of pluripotent stem cells from adult human fibroblasts by defined factors
    • Takahashi K., et al. Induction of pluripotent stem cells from adult human fibroblasts by defined factors. Cell 2007, 131:861-872.
    • (2007) Cell , vol.131 , pp. 861-872
    • Takahashi, K.1
  • 177
    • 0035656305 scopus 로고    scopus 로고
    • DNA methylation is a critical cell-intrinsic determinant of astrocyte differentiation in the fetal brain
    • Takizawa T., et al. DNA methylation is a critical cell-intrinsic determinant of astrocyte differentiation in the fetal brain. Dev. Cell 2001, 1:749-758.
    • (2001) Dev. Cell , vol.1 , pp. 749-758
    • Takizawa, T.1
  • 178
    • 33747827189 scopus 로고    scopus 로고
    • NMDA-receptor-mediated, cell-specific integration of new neurons in adult dentate gyrus
    • Tashiro A., et al. NMDA-receptor-mediated, cell-specific integration of new neurons in adult dentate gyrus. Nature 2006, 442:929-933.
    • (2006) Nature , vol.442 , pp. 929-933
    • Tashiro, A.1
  • 179
    • 50849102656 scopus 로고    scopus 로고
    • A specialized vascular niche for adult neural stem cells
    • Tavazoie M., et al. A specialized vascular niche for adult neural stem cells. Cell Stem Cell 2008, 3:279-288.
    • (2008) Cell Stem Cell , vol.3 , pp. 279-288
    • Tavazoie, M.1
  • 180
    • 0035499887 scopus 로고    scopus 로고
    • The development of neural stem cells
    • Temple S. The development of neural stem cells. Nature 2001, 414:112-117.
    • (2001) Nature , vol.414 , pp. 112-117
    • Temple, S.1
  • 181
    • 0034676035 scopus 로고    scopus 로고
    • Mammalian achaete-scute and atonal homologs regulate neuronal versus glial fate determination in the central nervous system
    • Tomita K., et al. Mammalian achaete-scute and atonal homologs regulate neuronal versus glial fate determination in the central nervous system. EMBO J. 2000, 19:5460-5472.
    • (2000) EMBO J. , vol.19 , pp. 5460-5472
    • Tomita, K.1
  • 182
    • 24644506108 scopus 로고    scopus 로고
    • GABAergic excitation promotes neuronal differentiation in adult hippocampal progenitor cells
    • Tozuka Y., et al. GABAergic excitation promotes neuronal differentiation in adult hippocampal progenitor cells. Neuron 2005, 47:803-815.
    • (2005) Neuron , vol.47 , pp. 803-815
    • Tozuka, Y.1
  • 183
    • 0037134040 scopus 로고    scopus 로고
    • DNA repair pathway stimulated by the forkhead transcription factor FOXO3a through the Gadd45 protein
    • Tran H., et al. DNA repair pathway stimulated by the forkhead transcription factor FOXO3a through the Gadd45 protein. Science 2002, 296:530-534.
    • (2002) Science , vol.296 , pp. 530-534
    • Tran, H.1
  • 184
    • 3042589127 scopus 로고    scopus 로고
    • Histone modifications at gene promoter regions in rat hippocampus after acute and chronic electroconvulsive seizures
    • Tsankova N.M., et al. Histone modifications at gene promoter regions in rat hippocampus after acute and chronic electroconvulsive seizures. J. Neurosci. 2004, 24:5603-5610.
    • (2004) J. Neurosci. , vol.24 , pp. 5603-5610
    • Tsankova, N.M.1
  • 185
    • 33645357786 scopus 로고    scopus 로고
    • Sustained hippocampal chromatin regulation in a mouse model of depression and antidepressant action
    • Tsankova N.M., et al. Sustained hippocampal chromatin regulation in a mouse model of depression and antidepressant action. Nat. Neurosci. 2006, 9:519-525.
    • (2006) Nat. Neurosci. , vol.9 , pp. 519-525
    • Tsankova, N.M.1
  • 186
    • 68549087008 scopus 로고    scopus 로고
    • Neuronal differentiation of neural precursor cells is promoted by the methyl-CpG-binding protein MeCP2
    • Tsujimura K., et al. Neuronal differentiation of neural precursor cells is promoted by the methyl-CpG-binding protein MeCP2. Exp. Neurol. 2009, 219:104-111.
    • (2009) Exp. Neurol. , vol.219 , pp. 104-111
    • Tsujimura, K.1
  • 187
    • 0033848849 scopus 로고    scopus 로고
    • Histone acetylation and an epigenetic code
    • Turner B.M. Histone acetylation and an epigenetic code. Bioessays 2000, 22:836-845.
    • (2000) Bioessays , vol.22 , pp. 836-845
    • Turner, B.M.1
  • 188
    • 74449087273 scopus 로고    scopus 로고
    • Valproic acid reduces spatial working memory and cell proliferation in the hippocampus
    • Umka J., et al. Valproic acid reduces spatial working memory and cell proliferation in the hippocampus. Neuroscience 2009, 166:15-22.
    • (2009) Neuroscience , vol.166 , pp. 15-22
    • Umka, J.1
  • 189
    • 0033539607 scopus 로고    scopus 로고
    • Running enhances neurogenesis, learning, and long-term potentiation in mice
    • van Praag H., et al. Running enhances neurogenesis, learning, and long-term potentiation in mice. Proc. Natl. Acad. Sci. U. S. A. 1999, 96:13427-13431.
    • (1999) Proc. Natl. Acad. Sci. U. S. A. , vol.96 , pp. 13427-13431
    • van Praag, H.1
  • 190
    • 66349125663 scopus 로고    scopus 로고
    • Lithium and neuropsychiatric therapeutics: neuroplasticity via glycogen synthase kinase-3beta, beta-catenin, and neurotrophin cascades
    • Wada A. Lithium and neuropsychiatric therapeutics: neuroplasticity via glycogen synthase kinase-3beta, beta-catenin, and neurotrophin cascades. J. Pharmacol. Sci. 2009, 110:14-28.
    • (2009) J. Pharmacol. Sci. , vol.110 , pp. 14-28
    • Wada, A.1
  • 191
    • 42649130264 scopus 로고    scopus 로고
    • Neurons derived from reprogrammed fibroblasts functionally integrate into the fetal brain and improve symptoms of rats with Parkinson's disease
    • Wernig M., et al. Neurons derived from reprogrammed fibroblasts functionally integrate into the fetal brain and improve symptoms of rats with Parkinson's disease. Proc. Natl. Acad. Sci. U. S. A. 2008, 105:5856-5861.
    • (2008) Proc. Natl. Acad. Sci. U. S. A. , vol.105 , pp. 5856-5861
    • Wernig, M.1
  • 192
    • 66149149801 scopus 로고    scopus 로고
    • Reversing DNA methylation: new insights from neuronal activity-induced Gadd45b in adult neurogenesis
    • Wu H., Sun Y.E. Reversing DNA methylation: new insights from neuronal activity-induced Gadd45b in adult neurogenesis. Sci. Signal. 2009, 2:pe17.
    • (2009) Sci. Signal. , vol.2
    • Wu, H.1    Sun, Y.E.2
  • 193
    • 34748887795 scopus 로고    scopus 로고
    • Regulation of dendritic development by neuron-specific chromatin remodeling complexes
    • Wu J.I., et al. Regulation of dendritic development by neuron-specific chromatin remodeling complexes. Neuron 2007, 56:94-108.
    • (2007) Neuron , vol.56 , pp. 94-108
    • Wu, J.I.1
  • 194
    • 10444239340 scopus 로고    scopus 로고
    • Repetitive cocaine administration decreases neurogenesis in adult rat hippocampus
    • Yamaguchi M., et al. Repetitive cocaine administration decreases neurogenesis in adult rat hippocampus. Ann. N. Y. Acad. Sci. 2004, 1025:351-362.
    • (2004) Ann. N. Y. Acad. Sci. , vol.1025 , pp. 351-362
    • Yamaguchi, M.1
  • 195
    • 67949083572 scopus 로고    scopus 로고
    • MicroRNA-mediated switching of chromatin-remodelling complexes in neural development
    • Yoo A.S., et al. MicroRNA-mediated switching of chromatin-remodelling complexes in neural development. Nature 2009, 460:642-646.
    • (2009) Nature , vol.460 , pp. 642-646
    • Yoo, A.S.1
  • 196
    • 58549095646 scopus 로고    scopus 로고
    • Valproic acid promotes neuronal differentiation by induction of proneural factors in association with H4 acetylation
    • Yu I.T., et al. Valproic acid promotes neuronal differentiation by induction of proneural factors in association with H4 acetylation. Neuropharmacology 2009, 56:473-480.
    • (2009) Neuropharmacology , vol.56 , pp. 473-480
    • Yu, I.T.1
  • 197
    • 71849113134 scopus 로고    scopus 로고
    • Increased hippocampal neurogenesis in the progressive stage of Alzheimer's disease phenotype in an APP/PS1 double transgenic mouse model
    • Yu Y., et al. Increased hippocampal neurogenesis in the progressive stage of Alzheimer's disease phenotype in an APP/PS1 double transgenic mouse model. Hippocampus 2009, 19:1247-1253.
    • (2009) Hippocampus , vol.19 , pp. 1247-1253
    • Yu, Y.1
  • 198
    • 0037636512 scopus 로고    scopus 로고
    • Mice lacking methyl-CpG binding protein 1 have deficits in adult neurogenesis and hippocampal function
    • Zhao X., et al. Mice lacking methyl-CpG binding protein 1 have deficits in adult neurogenesis and hippocampal function. Proc. Natl. Acad. Sci. U. S. A. 2003, 100:6777-6782.
    • (2003) Proc. Natl. Acad. Sci. U. S. A. , vol.100 , pp. 6777-6782
    • Zhao, X.1
  • 199
    • 30644474606 scopus 로고    scopus 로고
    • Distinct morphological stages of dentate granule neuron maturation in the adult mouse hippocampus
    • Zhao C., et al. Distinct morphological stages of dentate granule neuron maturation in the adult mouse hippocampus. J. Neurosci. 2006, 26:3-11.
    • (2006) J. Neurosci. , vol.26 , pp. 3-11
    • Zhao, C.1
  • 200
    • 33847258237 scopus 로고    scopus 로고
    • Long-lasting impairment in hippocampal neurogenesis associated with amyloid deposition in a knock-in mouse model of familial Alzheimer's disease
    • Zhang C., et al. Long-lasting impairment in hippocampal neurogenesis associated with amyloid deposition in a knock-in mouse model of familial Alzheimer's disease. Exp. Neurol. 2007, 204:77-87.
    • (2007) Exp. Neurol. , vol.204 , pp. 77-87
    • Zhang, C.1
  • 201
    • 39149107803 scopus 로고    scopus 로고
    • Mechanisms and functional implications of adult neurogenesis
    • Zhao C., et al. Mechanisms and functional implications of adult neurogenesis. Cell 2008, 132:645-660.
    • (2008) Cell , vol.132 , pp. 645-660
    • Zhao, C.1
  • 202
    • 73349104113 scopus 로고    scopus 로고
    • Active DNA demethylation mediated by DNA glycosylases
    • Zhu J.K. Active DNA demethylation mediated by DNA glycosylases. Annu. Rev. Genet. 2009, 43:143-166.
    • (2009) Annu. Rev. Genet. , vol.43 , pp. 143-166
    • Zhu, J.K.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.