메뉴 건너뛰기




Volumn 112, Issue , 2016, Pages 99-118

Modulation of learning and memory by natural polyamines

Author keywords

Arcaine; Learning; Memory; Rat; Spermidine; Spermine

Indexed keywords

ACETYLCHOLINESTERASE; AMPA RECEPTOR; ARCAINE; CASEIN KINASE II; CYCLIC AMP DEPENDENT PROTEIN KINASE; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN; ENDOTHELIAL NITRIC OXIDE SYNTHASE; IFENPRODIL; INDUCIBLE NITRIC OXIDE SYNTHASE; ION CHANNEL; KAINIC ACID RECEPTOR; KINASE SUPPRESSOR OF RAS; LIPOPOLYSACCHARIDE; MORPHINE; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; NON RECEPTOR PROTEIN TYROSINE PHOSPHATASE 2; NUCLEIC ACID; PROTEIN KINASE C; PROTEIN SERINE THREONINE KINASE; PUTRESCINE; QUINOLINIC ACID; SPERMIDINE; SPERMINE; STAT1 PROTEIN; STAT3 PROTEIN; TRAXOPRODIL; UNCLASSIFIED DRUG;

EID: 84962460148     PISSN: 10436618     EISSN: 10961186     Source Type: Journal    
DOI: 10.1016/j.phrs.2016.03.023     Document Type: Review
Times cited : (71)

References (333)
  • 2
    • 84896319384 scopus 로고    scopus 로고
    • Polyamines and membrane transporters
    • [2] Abdulhussein, A.A., Wallace, H.M., Polyamines and membrane transporters. Amino Acids 46 (2014), 655–660.
    • (2014) Amino Acids , vol.46 , pp. 655-660
    • Abdulhussein, A.A.1    Wallace, H.M.2
  • 3
    • 0027456616 scopus 로고
    • Spermine promotes the survival of primary cultured brain neurons
    • [3] Abe, K., Chida, N., Nishiyama, N., Saito, H., Spermine promotes the survival of primary cultured brain neurons. Brain Res. 605 (1993), 322–326.
    • (1993) Brain Res. , vol.605 , pp. 322-326
    • Abe, K.1    Chida, N.2    Nishiyama, N.3    Saito, H.4
  • 4
    • 80054761323 scopus 로고    scopus 로고
    • Effects of elevation of brain magnesium on fear conditioning, fear extinction, and synaptic plasticity in the infralimbic prefrontal cortex and lateral amygdala
    • [4] Abumaria, N., Yin, B., Zhang, L., Li, X.Y., Chen, T., Descalzi, G., Zhao, L., Ahn, M., Luo, L., Ran, C., Zhuo, M., Liu, G., Effects of elevation of brain magnesium on fear conditioning, fear extinction, and synaptic plasticity in the infralimbic prefrontal cortex and lateral amygdala. J. Neurosci. 31 (2011), 14871–14881.
    • (2011) J. Neurosci. , vol.31 , pp. 14871-14881
    • Abumaria, N.1    Yin, B.2    Zhang, L.3    Li, X.Y.4    Chen, T.5    Descalzi, G.6    Zhao, L.7    Ahn, M.8    Luo, L.9    Ran, C.10    Zhuo, M.11    Liu, G.12
  • 5
    • 33646845297 scopus 로고    scopus 로고
    • Polyamines are potent ligands for the capsaicin receptor TRPV1
    • [5] Ahern, G.P., Wang, X., Miyares, R.L., Polyamines are potent ligands for the capsaicin receptor TRPV1. J. Biol. Chem. 281 (2006), 8991–8995.
    • (2006) J. Biol. Chem. , vol.281 , pp. 8991-8995
    • Ahern, G.P.1    Wang, X.2    Miyares, R.L.3
  • 6
    • 0016777303 scopus 로고
    • The actions of spermidine and spermine on the central nervous system
    • [6] Anderson, D.J., Crossland, J., Shaw, G.G., The actions of spermidine and spermine on the central nervous system. Neuropharmacology 14 (1975), 571–577.
    • (1975) Neuropharmacology , vol.14 , pp. 571-577
    • Anderson, D.J.1    Crossland, J.2    Shaw, G.G.3
  • 8
    • 84860889573 scopus 로고    scopus 로고
    • The novel object recognition memory: neurobiology, test procedure, and its modifications
    • [8] Antunes, M., Biala, G., The novel object recognition memory: neurobiology, test procedure, and its modifications. Cogn. Process. 13 (2011), 93–110.
    • (2011) Cogn. Process. , vol.13 , pp. 93-110
    • Antunes, M.1    Biala, G.2
  • 9
    • 0033000688 scopus 로고    scopus 로고
    • Spermine and arcaine block and permeate N-methyl-D-aspartate receptor channels
    • [9] Araneda, R.C., Lan, J.-Y., Zheng, X., Zukin, R.S., Bennett, M.V.L., Spermine and arcaine block and permeate N-methyl-D-aspartate receptor channels. Biophys. J. 76 (1999), 2899–2911.
    • (1999) Biophys. J. , vol.76 , pp. 2899-2911
    • Araneda, R.C.1    Lan, J.-Y.2    Zheng, X.3    Zukin, R.S.4    Bennett, M.V.L.5
  • 10
    • 0032705119 scopus 로고    scopus 로고
    • Memory dissociation: the approach to the study of retrieval processes
    • [10] Arkhipov, V.I., Memory dissociation: the approach to the study of retrieval processes. Behav. Brain Res. 106 (1999), 39–46.
    • (1999) Behav. Brain Res. , vol.106 , pp. 39-46
    • Arkhipov, V.I.1
  • 11
    • 28444461786 scopus 로고    scopus 로고
    • Naturally occurring polyamines: interaction with macromolecules
    • [11] Bachrach, U., Naturally occurring polyamines: interaction with macromolecules. Curr. Protein Pept. Sci. 6 (2005), 559–566.
    • (2005) Curr. Protein Pept. Sci. , vol.6 , pp. 559-566
    • Bachrach, U.1
  • 12
    • 79952199559 scopus 로고    scopus 로고
    • The early history of polyamine research
    • [12] Bachrach, U., The early history of polyamine research. Plant Physiol. Biochem. 48 (2010), 490–495.
    • (2010) Plant Physiol. Biochem. , vol.48 , pp. 490-495
    • Bachrach, U.1
  • 13
    • 0342647787 scopus 로고    scopus 로고
    • Permeation and block of rat glur6 glutamate receptor channels by internal and external polyamines
    • [13] Bähring, R., Bowie, D., Benveniste, M., Mayer, M.L., Permeation and block of rat glur6 glutamate receptor channels by internal and external polyamines. J. Physiol. 502 (1997), 575–589.
    • (1997) J. Physiol. , vol.502 , pp. 575-589
    • Bähring, R.1    Bowie, D.2    Benveniste, M.3    Mayer, M.L.4
  • 14
    • 0030006443 scopus 로고    scopus 로고
    • The NMDA antagonist MK-801 blocks the extinction of Pavlovian fear conditioning
    • [14] Baker, J.D., Azorlosa, J.L., The NMDA antagonist MK-801 blocks the extinction of Pavlovian fear conditioning. Behav. Neurosci. 110 (1996), 618–620.
    • (1996) Behav. Neurosci. , vol.110 , pp. 618-620
    • Baker, J.D.1    Azorlosa, J.L.2
  • 15
    • 84896297550 scopus 로고    scopus 로고
    • Entorhinal cortex contribution to contextual fear conditioning extinction and reconsolidation in rats
    • [15] Baldi, E., Bucherelli, C., Entorhinal cortex contribution to contextual fear conditioning extinction and reconsolidation in rats. Neurobiol. Learn. Mem. 110 (2014), 64–71.
    • (2014) Neurobiol. Learn. Mem. , vol.110 , pp. 64-71
    • Baldi, E.1    Bucherelli, C.2
  • 16
    • 55149122439 scopus 로고    scopus 로고
    • Differential roles of the basolateral amygdala and nucleus basalis magnocellularis during post-reactivation contextual fear conditioning reconsolidation in rats
    • [16] Baldi, E., Mariottini, C., Bucherelli, C., Differential roles of the basolateral amygdala and nucleus basalis magnocellularis during post-reactivation contextual fear conditioning reconsolidation in rats. Neurobiol. Learn. Mem. 90 (2008), 604–609.
    • (2008) Neurobiol. Learn. Mem. , vol.90 , pp. 604-609
    • Baldi, E.1    Mariottini, C.2    Bucherelli, C.3
  • 17
    • 0019180698 scopus 로고
    • Role of ornithine decarboxylase in cardiac growth and hypertrophy
    • [17] Bartolome, J., Huguenard, J., Slotkin, T.A., Role of ornithine decarboxylase in cardiac growth and hypertrophy. Science 210 (1980), 793–794.
    • (1980) Science , vol.210 , pp. 793-794
    • Bartolome, J.1    Huguenard, J.2    Slotkin, T.A.3
  • 18
    • 84861575699 scopus 로고    scopus 로고
    • Channel properties reveal differential expression of TARPed and TARPless AMPARs in stargazer neurons
    • [18] Bats, C., Soto, D., Studniarczyk, D., Farrant, M., Cull-Candy, S.G., Channel properties reveal differential expression of TARPed and TARPless AMPARs in stargazer neurons. Nat. Neurosci. 15 (2012), 853–861.
    • (2012) Nat. Neurosci. , vol.15 , pp. 853-861
    • Bats, C.1    Soto, D.2    Studniarczyk, D.3    Farrant, M.4    Cull-Candy, S.G.5
  • 19
    • 78651174131 scopus 로고
    • Reversal learning of an avoidance response as a function of prior fear conditioning and fear extinction
    • [19] Baum, M., Reversal learning of an avoidance response as a function of prior fear conditioning and fear extinction. Can. J. Psychol. 19 (1965), 85–93.
    • (1965) Can. J. Psychol. , vol.19 , pp. 85-93
    • Baum, M.1
  • 20
    • 0022446150 scopus 로고
    • Replication of the neurochemical characteristics of Huntington's disease by quinolinic acid
    • [20] Beal, M.F., Kowall, N.W., Ellison, D.W., Mazurek, M.F., Swartz, K.J., Martin, J.B., Replication of the neurochemical characteristics of Huntington's disease by quinolinic acid. Nature 321 (1986), 168–171.
    • (1986) Nature , vol.321 , pp. 168-171
    • Beal, M.F.1    Kowall, N.W.2    Ellison, D.W.3    Mazurek, M.F.4    Swartz, K.J.5    Martin, J.B.6
  • 21
    • 84984538874 scopus 로고    scopus 로고
    • Polyamines reduces lipid peroxidation induced by different pro-oxidant agents
    • [21] Belle, N.A., Dalmolin, G.D., Fonini, G., Rubin, M.A., Rocha, J.B., Polyamines reduces lipid peroxidation induced by different pro-oxidant agents. Brain Res. 1008 (2004), 245–251.
    • (2004) Brain Res. , vol.1008 , pp. 245-251
    • Belle, N.A.1    Dalmolin, G.D.2    Fonini, G.3    Rubin, M.A.4    Rocha, J.B.5
  • 22
    • 0022230177 scopus 로고
    • Efficacy of oral physostigmine in primary degenerative dementia. A double-blind study of response to different dose level
    • [22] Beller, S.A., Overall, J.E., Swann, A.C., Efficacy of oral physostigmine in primary degenerative dementia. A double-blind study of response to different dose level. Psychopharmacology (Berl) 87 (1985), 147–151.
    • (1985) Psychopharmacology (Berl) , vol.87 , pp. 147-151
    • Beller, S.A.1    Overall, J.E.2    Swann, A.C.3
  • 25
    • 0027174665 scopus 로고
    • Multiple effects of spermine on N-methyl-D-aspartic acid receptor responses of rat cultured hippocampal-neurons
    • [25] Benveniste, M., Mayer, M.L., Multiple effects of spermine on N-methyl-D-aspartic acid receptor responses of rat cultured hippocampal-neurons. J. Physiol.-Lond. 464 (1993), 131–163.
    • (1993) J. Physiol.-Lond. , vol.464 , pp. 131-163
    • Benveniste, M.1    Mayer, M.L.2
  • 27
    • 0031196961 scopus 로고    scopus 로고
    • Involvement of hippocampal AMPA glutamate receptor changes and the cAMP/protein kinase A/CREB-P signalling pathway in memory consolidation of an avoidance task in rats
    • [27] Bernabeu, R., Cammarota, M., Izquierdo, I., Medina, J.H., Involvement of hippocampal AMPA glutamate receptor changes and the cAMP/protein kinase A/CREB-P signalling pathway in memory consolidation of an avoidance task in rats. Braz. J. Med. Biol. Res. 30 (1997), 961–965.
    • (1997) Braz. J. Med. Biol. Res. , vol.30 , pp. 961-965
    • Bernabeu, R.1    Cammarota, M.2    Izquierdo, I.3    Medina, J.H.4
  • 28
    • 0028997064 scopus 로고
    • Learning-specific, time-dependent increase in [3H]phorbol dibutyrate binding to protein kinase C in selected regions of the rat brain
    • [28] Bernabeu, R., Izquierdo, I., Cammarota, M., Jerusalinsky, D., Medina, J.H., Learning-specific, time-dependent increase in [3H]phorbol dibutyrate binding to protein kinase C in selected regions of the rat brain. Brain Res. 685 (1995), 163–168.
    • (1995) Brain Res. , vol.685 , pp. 163-168
    • Bernabeu, R.1    Izquierdo, I.2    Cammarota, M.3    Jerusalinsky, D.4    Medina, J.H.5
  • 29
    • 0030989170 scopus 로고    scopus 로고
    • Involvement of hippocampal cAMP/cAMP-dependent protein kinase signaling pathways in a late memory consolidation phase of aversively motivated learning in rats
    • [29] Bernabeu, R., Bevilaqua, L., Ardenghi, P., Bromberg, E., Schmitz, P., Bianchin, M., Izquierdo, I., Medina, J.H., Involvement of hippocampal cAMP/cAMP-dependent protein kinase signaling pathways in a late memory consolidation phase of aversively motivated learning in rats. Proc. Natl. Acad. Sci. U. S. A. 94 (1997), 7041–7046.
    • (1997) Proc. Natl. Acad. Sci. U. S. A. , vol.94 , pp. 7041-7046
    • Bernabeu, R.1    Bevilaqua, L.2    Ardenghi, P.3    Bromberg, E.4    Schmitz, P.5    Bianchin, M.6    Izquierdo, I.7    Medina, J.H.8
  • 30
    • 0028961549 scopus 로고
    • Increased immunostaining for L-ornithine decarboxylase occurs in neocortical neurons of Alzheimer's disease patients
    • [30] Bernstein, H.G., Muller, M., Increased immunostaining for L-ornithine decarboxylase occurs in neocortical neurons of Alzheimer's disease patients. Neurosci. Lett. 186 (1995), 123–126.
    • (1995) Neurosci. Lett. , vol.186 , pp. 123-126
    • Bernstein, H.G.1    Muller, M.2
  • 31
    • 0344628699 scopus 로고    scopus 로고
    • The cellular localization of the L-ornithine decarboxylase/polyamine system in normal and diseased central nervous systems
    • [31] Bernstein, H.G., Muller, M., The cellular localization of the L-ornithine decarboxylase/polyamine system in normal and diseased central nervous systems. Prog. Neurobiol. 57 (1999), 485–505.
    • (1999) Prog. Neurobiol. , vol.57 , pp. 485-505
    • Bernstein, H.G.1    Muller, M.2
  • 32
    • 0035272382 scopus 로고    scopus 로고
    • Binding of polyamine-containing toxins in the vestibule of the nicotinic acetylcholine receptor ion channel
    • [32] Bixel, M.G., Krauss, M., Weise, C., Bolognesi, M.L., Rosini, M., Usherwood, P.N., Melchiorre, C., Hucho, F., Binding of polyamine-containing toxins in the vestibule of the nicotinic acetylcholine receptor ion channel. Farmaco 56 (2001), 133–135.
    • (2001) Farmaco , vol.56 , pp. 133-135
    • Bixel, M.G.1    Krauss, M.2    Weise, C.3    Bolognesi, M.L.4    Rosini, M.5    Usherwood, P.N.6    Melchiorre, C.7    Hucho, F.8
  • 34
    • 33845768784 scopus 로고    scopus 로고
    • Microglia-mediated neurotoxicity: uncovering the molecular mechanisms
    • [34] Block, M.L., Zecca, L., Hong, J.S., Microglia-mediated neurotoxicity: uncovering the molecular mechanisms. Nat. Rev. Neurosci. 8 (2007), 57–69.
    • (2007) Nat. Rev. Neurosci. , vol.8 , pp. 57-69
    • Block, M.L.1    Zecca, L.2    Hong, J.S.3
  • 35
    • 0037338353 scopus 로고    scopus 로고
    • On the role of nitric oxide in hippocampal long-term potentiation
    • [35] Bon, C.L., Garthwaite, J., On the role of nitric oxide in hippocampal long-term potentiation. J. Neurosci. 23 (2003), 1941–1948.
    • (2003) J. Neurosci. , vol.23 , pp. 1941-1948
    • Bon, C.L.1    Garthwaite, J.2
  • 38
    • 0026486263 scopus 로고
    • Neurotoxic effects of the intrastriatal injection of spermine and spermidine: lack of involvement of NMDA receptors
    • [38] Bourdiol, F., Fage, D., Serrano, A., Carter, C., Benavides, J., Scatton, B., Neurotoxic effects of the intrastriatal injection of spermine and spermidine: lack of involvement of NMDA receptors. Brain Res. 596 (1992), 183–188.
    • (1992) Brain Res. , vol.596 , pp. 183-188
    • Bourdiol, F.1    Fage, D.2    Serrano, A.3    Carter, C.4    Benavides, J.5    Scatton, B.6
  • 39
    • 0029082204 scopus 로고
    • Inward rectification of both AMPA and kainate subtype glutamate receptors generated by polyamine-mediated ion channel block
    • [39] Bowie, D., Mayer, M.L., Inward rectification of both AMPA and kainate subtype glutamate receptors generated by polyamine-mediated ion channel block. Neuron 15 (1995), 453–462.
    • (1995) Neuron , vol.15 , pp. 453-462
    • Bowie, D.1    Mayer, M.L.2
  • 40
    • 84989157031 scopus 로고    scopus 로고
    • Pharmaceutical prepn. for immuno-suppression—comprises immunosuppressive agent and ornithine decarboxylase inhibitor, for treating auto-immune diseases or organ transplant rejection. Merrell Dow Pharm Inc. (Rich-C), 2016
    • [40] T.L. Bowlin, Pharmaceutical prepn. for immuno-suppression—comprises immunosuppressive agent and ornithine decarboxylase inhibitor, for treating auto-immune diseases or organ transplant rejection. Merrell Dow Pharm Inc. (Rich-C), 2016.
    • Bowlin, T.L.1
  • 41
    • 75449116118 scopus 로고    scopus 로고
    • Object recognition memory and the rodent hippocampus
    • [41] Broadbent, N.J., Gaskin, S., Squire, L.R., Clark, R.E., Object recognition memory and the rodent hippocampus. Learn. Mem. 17 (2009), 5–11.
    • (2009) Learn. Mem. , vol.17 , pp. 5-11
    • Broadbent, N.J.1    Gaskin, S.2    Squire, L.R.3    Clark, R.E.4
  • 42
  • 43
    • 0029028313 scopus 로고
    • Fractional calcium currents through recombinant GluR channels of the NMDA, AMPA and kainate receptor subtypes
    • [43] Burnashev, N., Zhou, Z., Neher, E., Sakmann, B., Fractional calcium currents through recombinant GluR channels of the NMDA, AMPA and kainate receptor subtypes. J. Physiol. 485:Pt 2 (1995), 403–418.
    • (1995) J. Physiol. , vol.485 , pp. 403-418
    • Burnashev, N.1    Zhou, Z.2    Neher, E.3    Sakmann, B.4
  • 44
    • 34249898907 scopus 로고    scopus 로고
    • Systemic administration of polyaminergic agents modulate fear conditioning in rats
    • [44] Camera, K., Mello, C.F., Ceretta, A.P., Rubin, M.A., Systemic administration of polyaminergic agents modulate fear conditioning in rats. Psychopharmacology (Berl) 192 (2007), 457–464.
    • (2007) Psychopharmacology (Berl) , vol.192 , pp. 457-464
    • Camera, K.1    Mello, C.F.2    Ceretta, A.P.3    Rubin, M.A.4
  • 45
    • 0030895199 scopus 로고    scopus 로고
    • B-50/GAP-43 phosphorylation and PKC activity are increased in rat hippocampal synaptosomal membranes after an inhibitory avoidance training
    • [45] Cammarota, M., Paratcha, G., Levi de Stein, M., Bernabeu, R., Izquierdo, I., Medina, J.H., B-50/GAP-43 phosphorylation and PKC activity are increased in rat hippocampal synaptosomal membranes after an inhibitory avoidance training. Neurochem. Res. 22 (1997), 499–505.
    • (1997) Neurochem. Res. , vol.22 , pp. 499-505
    • Cammarota, M.1    Paratcha, G.2    Levi de Stein, M.3    Bernabeu, R.4    Izquierdo, I.5    Medina, J.H.6
  • 46
    • 12144271690 scopus 로고    scopus 로고
    • The PSD95-nNOS interface: a target for inhibition of excitotoxic p38 stress-activated protein kinase activation and cell death
    • [46] Cao, J., Viholainen, J.I., Dart, C., Warwick, H.K., Leyland, M.L., Courtney, M.J., The PSD95-nNOS interface: a target for inhibition of excitotoxic p38 stress-activated protein kinase activation and cell death. J. Cell Biol. 168 (2005), 117–126.
    • (2005) J. Cell Biol. , vol.168 , pp. 117-126
    • Cao, J.1    Viholainen, J.I.2    Dart, C.3    Warwick, H.K.4    Leyland, M.L.5    Courtney, M.J.6
  • 50
    • 84884718175 scopus 로고    scopus 로고
    • Memory reconsolidation allows the consolidation of a concomitant weak learning through a synaptic tagging and capture mechanism
    • [50] Cassini, L.F., Sierra, R.O., Haubrich, J., Crestani, A.P., Santana, F., de Oliveira Alvares, L., Quillfeldt, J.A., Memory reconsolidation allows the consolidation of a concomitant weak learning through a synaptic tagging and capture mechanism. Hippocampus 23 (2013), 931–941.
    • (2013) Hippocampus , vol.23 , pp. 931-941
    • Cassini, L.F.1    Sierra, R.O.2    Haubrich, J.3    Crestani, A.P.4    Santana, F.5    de Oliveira Alvares, L.6    Quillfeldt, J.A.7
  • 51
    • 80052788315 scopus 로고    scopus 로고
    • Guanylated diamines, triamines, and polyamines: chemistry and biological properties
    • [51] Castagnolo, D., Schenone, S., Botta, M., Guanylated diamines, triamines, and polyamines: chemistry and biological properties. Chem. Rev. 111 (2011), 5247–5300.
    • (2011) Chem. Rev. , vol.111 , pp. 5247-5300
    • Castagnolo, D.1    Schenone, S.2    Botta, M.3
  • 52
    • 0032704552 scopus 로고    scopus 로고
    • MK-801-induced disruptions of one-trial inhibitory avoidance are potentiated by stress and reversed by naltrexone
    • [52] Castellano, C., Cestari, V., Ciamei, A., Pavone, F., MK-801-induced disruptions of one-trial inhibitory avoidance are potentiated by stress and reversed by naltrexone. Neurobiol. Learn Mem. 72 (1999), 215–229.
    • (1999) Neurobiol. Learn Mem. , vol.72 , pp. 215-229
    • Castellano, C.1    Cestari, V.2    Ciamei, A.3    Pavone, F.4
  • 56
    • 0029995815 scopus 로고    scopus 로고
    • The neurochemical and behavioral effects of beta-amyloid peptide(25–35)
    • [56] Chen, S.Y., Wright, J.W., Barnes, C.D., The neurochemical and behavioral effects of beta-amyloid peptide(25–35). Brain Res. 720 (1996), 54–60.
    • (1996) Brain Res. , vol.720 , pp. 54-60
    • Chen, S.Y.1    Wright, J.W.2    Barnes, C.D.3
  • 57
    • 0027439945 scopus 로고
    • nMDA receptor activation increases cyclic AMP in area CA1 of the hippocampus via calcium/calmodulin stimulation of adenylyl cyclase
    • [57] Chetkovich, D.M., Sweatt, J.D., nMDA receptor activation increases cyclic AMP in area CA1 of the hippocampus via calcium/calmodulin stimulation of adenylyl cyclase. J. Neurochem. 61 (1993), 1933–1942.
    • (1993) J. Neurochem. , vol.61 , pp. 1933-1942
    • Chetkovich, D.M.1    Sweatt, J.D.2
  • 58
    • 0025952762 scopus 로고
    • N-Methyl-D-aspartate receptor activation increases cAMP levels and voltage-gated Ca2+ channel activity in area CA1 of hippocampus
    • [58] Chetkovich, D.M., Gray, R., Johnston, D., Sweatt, J.D., N-Methyl-D-aspartate receptor activation increases cAMP levels and voltage-gated Ca2+ channel activity in area CA1 of hippocampus. Proc. Natl. Acad. Sci. U. S. A. 88 (1991), 6467–6471.
    • (1991) Proc. Natl. Acad. Sci. U. S. A. , vol.88 , pp. 6467-6471
    • Chetkovich, D.M.1    Gray, R.2    Johnston, D.3    Sweatt, J.D.4
  • 59
    • 84881097682 scopus 로고    scopus 로고
    • Hippocampal Arc (Arg3.1) expression is induced by memory recall and required for memory reconsolidation in trace fear conditioning
    • [59] Chia, C., Otto, T., Hippocampal Arc (Arg3.1) expression is induced by memory recall and required for memory reconsolidation in trace fear conditioning. Neurobiol. Learn. Mem. 106 (2013), 48–55.
    • (2013) Neurobiol. Learn. Mem. , vol.106 , pp. 48-55
    • Chia, C.1    Otto, T.2
  • 60
    • 0026781607 scopus 로고
    • Spermine facilitates the generation of long-term potentiation of evoked potential in the dentate gyrus of anesthetized rats
    • [60] Chida, N., Saito, H., Abe, K., Spermine facilitates the generation of long-term potentiation of evoked potential in the dentate gyrus of anesthetized rats. Brain Res. 593 (1992), 57–62.
    • (1992) Brain Res. , vol.593 , pp. 57-62
    • Chida, N.1    Saito, H.2    Abe, K.3
  • 61
    • 0004139057 scopus 로고    scopus 로고
    • A Guide to the Polyamines
    • Oxford University Press New York
    • [61] Cohen, S.S., A Guide to the Polyamines. 1998, Oxford University Press, New York.
    • (1998)
    • Cohen, S.S.1
  • 62
    • 0023658653 scopus 로고
    • Synaptic plasticity. The role of NMDA receptors in learning and memory
    • [62] Collingridge, G., Synaptic plasticity. The role of NMDA receptors in learning and memory. Nature 330 (1987), 604–605.
    • (1987) Nature , vol.330 , pp. 604-605
    • Collingridge, G.1
  • 63
    • 33744970728 scopus 로고    scopus 로고
    • An inhibitor of DNA recombination blocks memory consolidation, but not reconsolidation, in context fear conditioning
    • [63] Colon-Cesario, M., Wang, J., Ramos, X., Garcia, H.G., Davila, J.J., Laguna, J., Rosado, C., Pena de Ortiz, S., An inhibitor of DNA recombination blocks memory consolidation, but not reconsolidation, in context fear conditioning. J. Neurosci. 26 (2006), 5524–5533.
    • (2006) J. Neurosci. , vol.26 , pp. 5524-5533
    • Colon-Cesario, M.1    Wang, J.2    Ramos, X.3    Garcia, H.G.4    Davila, J.J.5    Laguna, J.6    Rosado, C.7    Pena de Ortiz, S.8
  • 64
  • 65
    • 0032572588 scopus 로고    scopus 로고
    • Brain lesions and delayed water maze learning deficits after intracerebroventricular spermine
    • [65] Conway, E.L., Brain lesions and delayed water maze learning deficits after intracerebroventricular spermine. Brain Res. 800 (1998), 10–20.
    • (1998) Brain Res. , vol.800 , pp. 10-20
    • Conway, E.L.1
  • 66
    • 33745202578 scopus 로고    scopus 로고
    • Regulation of Ca2+-permeable AMPA receptors: synaptic plasticity and beyond
    • [66] Cull-Candy, S., Kelly, L., Farrant, M., Regulation of Ca2+-permeable AMPA receptors: synaptic plasticity and beyond. Curr. Opin. Neurobiol. 16 (2006), 288–297.
    • (2006) Curr. Opin. Neurobiol. , vol.16 , pp. 288-297
    • Cull-Candy, S.1    Kelly, L.2    Farrant, M.3
  • 68
    • 84857660543 scopus 로고    scopus 로고
    • NMDA receptors and fear extinction: implications for cognitive behavioral therapy
    • [68] Davis, M., NMDA receptors and fear extinction: implications for cognitive behavioral therapy. Dialogues Clin. Neurosci. 13 (2011), 463–474.
    • (2011) Dialogues Clin. Neurosci. , vol.13 , pp. 463-474
    • Davis, M.1
  • 69
    • 40549089913 scopus 로고    scopus 로고
    • Spermine induces cell death in cultured human embryonic cerebral cortical neurons through N-methyl-D-aspartate receptor activation
    • [69] de Vera, N., Martinez, E., Sanfeliu, C., Spermine induces cell death in cultured human embryonic cerebral cortical neurons through N-methyl-D-aspartate receptor activation. J. Neurosci. Res. 86 (2008), 861–872.
    • (2008) J. Neurosci. Res. , vol.86 , pp. 861-872
    • de Vera, N.1    Martinez, E.2    Sanfeliu, C.3
  • 70
    • 6344277186 scopus 로고    scopus 로고
    • Disruption of reconsolidation but not consolidation of auditory fear conditioning by noradrenergic blockade in the amygdala
    • [70] Debiec, J., Ledoux, J.E., Disruption of reconsolidation but not consolidation of auditory fear conditioning by noradrenergic blockade in the amygdala. Neuroscience 129 (2004), 267–272.
    • (2004) Neuroscience , vol.129 , pp. 267-272
    • Debiec, J.1    Ledoux, J.E.2
  • 71
    • 0015153848 scopus 로고
    • The cholinergic synapse and the site of memory
    • [71] Deutsch, J.A., The cholinergic synapse and the site of memory. Science 174 (1971), 788–794.
    • (1971) Science , vol.174 , pp. 788-794
    • Deutsch, J.A.1
  • 72
    • 0025943289 scopus 로고
    • Changes in polyamine levels in rat-brain after systemic kainic acid administration—relationship to convulsant activity and brain-damage
    • [72] Devera, N., Artigas, F., Serratosa, J., Martinez, E., Changes in polyamine levels in rat-brain after systemic kainic acid administration—relationship to convulsant activity and brain-damage. J. Neurochem. 57 (1991), 1–8.
    • (1991) J. Neurochem. , vol.57 , pp. 1-8
    • Devera, N.1    Artigas, F.2    Serratosa, J.3    Martinez, E.4
  • 73
    • 0025363346 scopus 로고
    • Excitotoxic injury of the neostriatum: a model for Huntington's disease
    • [73] DiFiglia, M., Excitotoxic injury of the neostriatum: a model for Huntington's disease. Trends Neurosci. 13 (1990), 286–289.
    • (1990) Trends Neurosci. , vol.13 , pp. 286-289
    • DiFiglia, M.1
  • 74
    • 84867620850 scopus 로고    scopus 로고
    • Mechanisms and implications of programmed translational frameshifting
    • [74] Dinman, J.D., Mechanisms and implications of programmed translational frameshifting. Wiley Interdiscip. Rev. RNA 3 (2012), 661–673.
    • (2012) Wiley Interdiscip. Rev. RNA , vol.3 , pp. 661-673
    • Dinman, J.D.1
  • 75
    • 79951542315 scopus 로고    scopus 로고
    • Extracellular spermine exacerbates ischemic neuronal injury through sensitization of ASIC1a channels to extracellular acidosis
    • [75] Duan, B., Wang, Y.Z., Yang, T., Chu, X.P., Yu, Y., Huang, Y., Cao, H., Hansen, J., Simon, R.P., Zhu, M.X., Xiong, Z.G., Xu, T.L., Extracellular spermine exacerbates ischemic neuronal injury through sensitization of ASIC1a channels to extracellular acidosis. J. Neurosci. 31 (2011), 2101–2112.
    • (2011) J. Neurosci. , vol.31 , pp. 2101-2112
    • Duan, B.1    Wang, Y.Z.2    Yang, T.3    Chu, X.P.4    Yu, Y.5    Huang, Y.6    Cao, H.7    Hansen, J.8    Simon, R.P.9    Zhu, M.X.10    Xiong, Z.G.11    Xu, T.L.12
  • 76
    • 1842590400 scopus 로고    scopus 로고
    • The neurobiology of consolidations, or, how stable is the engram?
    • [76] Dudai, Y., The neurobiology of consolidations, or, how stable is the engram?. Annu. Rev. Psychol. 55 (2004), 51–86.
    • (2004) Annu. Rev. Psychol. , vol.55 , pp. 51-86
    • Dudai, Y.1
  • 77
    • 5344226327 scopus 로고    scopus 로고
    • Rites of passage of the engram: reconsolidation and the lingering consolidation hypothesis
    • [77] Dudai, Y., Eisenberg, M., Rites of passage of the engram: reconsolidation and the lingering consolidation hypothesis. Neuron 44 (2004), 93–100.
    • (2004) Neuron , vol.44 , pp. 93-100
    • Dudai, Y.1    Eisenberg, M.2
  • 78
    • 84989198174 scopus 로고
    • Notes on spermine
    • [78] Dudley, H.W., Rosenheim, O., Notes on spermine. Biochem. J 19 (1925), 1034–1036.
    • (1925) Biochem. J , vol.19 , pp. 1034-1036
    • Dudley, H.W.1    Rosenheim, O.2
  • 79
    • 0344410111 scopus 로고
    • The chemical constitution of spermine. I. The isolation of spermine from animal tissues, and the preparation of its salts
    • [79] Dudley, H.W., Rosenheim, M.C., Rosenheim, O., The chemical constitution of spermine. I. The isolation of spermine from animal tissues, and the preparation of its salts. Biochem. J. 18 (1924), 1263–1272.
    • (1924) Biochem. J. , vol.18 , pp. 1263-1272
    • Dudley, H.W.1    Rosenheim, M.C.2    Rosenheim, O.3
  • 80
    • 0019483049 scopus 로고
    • The effect of alpha-difluoromethyl-ornithine on tumor growth, acute phase reactants, beta-2-microglobulin and hydroxyproline in kidney and bladder carcinomas
    • [80] Dunzendorfer, U., The effect of alpha-difluoromethyl-ornithine on tumor growth, acute phase reactants, beta-2-microglobulin and hydroxyproline in kidney and bladder carcinomas. Urol. Int. 36 (1981), 128–136.
    • (1981) Urol. Int. , vol.36 , pp. 128-136
    • Dunzendorfer, U.1
  • 81
    • 0027323130 scopus 로고
    • Splice variants of the N-methyl-D-aspartate receptor NR1 identify domains involved in regulation by polyamines and protein kinase C
    • [81] Durand, G.M., Bennett, M.V., Zukin, R.S., Splice variants of the N-methyl-D-aspartate receptor NR1 identify domains involved in regulation by polyamines and protein kinase C. Proc. Natl. Acad. Sci. U. S. A. 90 (1993), 6731–6735.
    • (1993) Proc. Natl. Acad. Sci. U. S. A. , vol.90 , pp. 6731-6735
    • Durand, G.M.1    Bennett, M.V.2    Zukin, R.S.3
  • 82
    • 0026686821 scopus 로고
    • Cloning of an apparent splice variant of the rat N-methyl-D-aspartate receptor NMDAR1 with altered sensitivity to polyamines and activators of protein kinase C
    • [82] Durand, G.M., Gregor, P., Zheng, X., Bennett, M.V., Uhl, G.R., Zukin, R.S., Cloning of an apparent splice variant of the rat N-methyl-D-aspartate receptor NMDAR1 with altered sensitivity to polyamines and activators of protein kinase C. Proc. Natl. Acad. Sci. U. S. A. 89 (1992), 9359–9363.
    • (1992) Proc. Natl. Acad. Sci. U. S. A. , vol.89 , pp. 9359-9363
    • Durand, G.M.1    Gregor, P.2    Zheng, X.3    Bennett, M.V.4    Uhl, G.R.5    Zukin, R.S.6
  • 83
    • 13244249854 scopus 로고    scopus 로고
    • Activation of extracellular signal-regulated kinase- mitogen-activated protein kinase cascade in the amygdala is required for memory reconsolidation of auditory fear conditioning
    • [83] Duvarci, S., Nader, K., LeDoux, J.E., Activation of extracellular signal-regulated kinase- mitogen-activated protein kinase cascade in the amygdala is required for memory reconsolidation of auditory fear conditioning. Eur. J. Neurosci. 21 (2005), 283–289.
    • (2005) Eur. J. Neurosci. , vol.21 , pp. 283-289
    • Duvarci, S.1    Nader, K.2    LeDoux, J.E.3
  • 84
    • 84901188809 scopus 로고    scopus 로고
    • TRPV1 in the central nervous system: synaptic plasticity, function, and pharmacological implications
    • [84] Edwards, J.G., TRPV1 in the central nervous system: synaptic plasticity, function, and pharmacological implications. Prog. Drug Res. 68 (2014), 77–104.
    • (2014) Prog. Drug Res. , vol.68 , pp. 77-104
    • Edwards, J.G.1
  • 85
    • 0024471524 scopus 로고
    • Ca2+/calmodulin sensitivity may be common to all forms of neural adenylate cyclase
    • [85] Eliot, L.S., Dudai, Y., Kandel, E.R., Abrams, T.W., Ca2+/calmodulin sensitivity may be common to all forms of neural adenylate cyclase. Proc. Natl. Acad. Sci. U. S. A. 86 (1989), 9564–9568.
    • (1989) Proc. Natl. Acad. Sci. U. S. A. , vol.86 , pp. 9564-9568
    • Eliot, L.S.1    Dudai, Y.2    Kandel, E.R.3    Abrams, T.W.4
  • 86
    • 0027521805 scopus 로고
    • Polyamine neurotoxicity is antagonized by dizocilpine in cultured chick cortical neurons
    • [86] Fahey, J.M., Pritchard, G.A., Miller, L.G., Polyamine neurotoxicity is antagonized by dizocilpine in cultured chick cortical neurons. Neurosci. Lett. 161 (1993), 109–112.
    • (1993) Neurosci. Lett. , vol.161 , pp. 109-112
    • Fahey, J.M.1    Pritchard, G.A.2    Miller, L.G.3
  • 87
    • 0032976615 scopus 로고    scopus 로고
    • The neuroanatomical and neurochemical basis of conditioned fear
    • [87] Fendt, M., Fanselow, M.S., The neuroanatomical and neurochemical basis of conditioned fear. Neurosci. Biobehav. Rev. 23 (1999), 743–760.
    • (1999) Neurosci. Biobehav. Rev. , vol.23 , pp. 743-760
    • Fendt, M.1    Fanselow, M.S.2
  • 88
    • 77957170637 scopus 로고    scopus 로고
    • Genetic and epigenetic influences on expression of spermine synthase and spermine oxidase in suicide completers
    • [88] Fiori, L.M., Turecki, G., Genetic and epigenetic influences on expression of spermine synthase and spermine oxidase in suicide completers. Int. J. Neuropsychopharmacol. 13 (2010), 725–736.
    • (2010) Int. J. Neuropsychopharmacol. , vol.13 , pp. 725-736
    • Fiori, L.M.1    Turecki, G.2
  • 89
    • 68049148368 scopus 로고    scopus 로고
    • Identification and characterization of spermidine/spermine N1-acetyltransferase promoter variants in suicide completers
    • [89] Fiori, L.M., Mechawar, N., Turecki, G., Identification and characterization of spermidine/spermine N1-acetyltransferase promoter variants in suicide completers. Biol. Psychiatry 66 (2009), 460–467.
    • (2009) Biol. Psychiatry , vol.66 , pp. 460-467
    • Fiori, L.M.1    Mechawar, N.2    Turecki, G.3
  • 90
    • 84864571573 scopus 로고    scopus 로고
    • Effects of histone modifications on increased expression of polyamine biosynthetic genes in suicide
    • [90] Fiori, L.M., Gross, J.A., Turecki, G., Effects of histone modifications on increased expression of polyamine biosynthetic genes in suicide. Int. J. Neuropsychopharmacol. 15 (2012), 1161–1166.
    • (2012) Int. J. Neuropsychopharmacol. , vol.15 , pp. 1161-1166
    • Fiori, L.M.1    Gross, J.A.2    Turecki, G.3
  • 94
    • 84878859619 scopus 로고    scopus 로고
    • An old test for new neurons: refining the Morris water maze to study the functional relevance of adult hippocampal neurogenesis
    • [94] Garthe, A., Kempermann, G., An old test for new neurons: refining the Morris water maze to study the functional relevance of adult hippocampal neurogenesis. Front. Neurosci., 7, 2013, 63.
    • (2013) Front. Neurosci. , vol.7 , pp. 63
    • Garthe, A.1    Kempermann, G.2
  • 95
    • 0026077959 scopus 로고
    • Glutamate, nitric oxide and cell-cell signalling in the nervous system
    • [95] Garthwaite, J., Glutamate, nitric oxide and cell-cell signalling in the nervous system. Trends Neurosci. 14 (1991), 60–67.
    • (1991) Trends Neurosci. , vol.14 , pp. 60-67
    • Garthwaite, J.1
  • 96
    • 84861198878 scopus 로고    scopus 로고
    • Role of TRPV1 in consolidation of fear memories depends on the averseness of the conditioning procedure
    • [96] Genro, B.P., de Oliveira Alvares, L., Quillfeldt, J.A., Role of TRPV1 in consolidation of fear memories depends on the averseness of the conditioning procedure. Neurobiol. Learn. Mem. 97 (2012), 355–360.
    • (2012) Neurobiol. Learn. Mem. , vol.97 , pp. 355-360
    • Genro, B.P.1    de Oliveira Alvares, L.2    Quillfeldt, J.A.3
  • 97
    • 84865490163 scopus 로고    scopus 로고
    • Inflammatory activation enhances NMDA-triggered Ca2+ signalling and IL-1beta secretion in primary cultures of rat astrocytes
    • [97] Gerard, F., Hansson, E., Inflammatory activation enhances NMDA-triggered Ca2+ signalling and IL-1beta secretion in primary cultures of rat astrocytes. Brain Res. 1473 (2012), 1–8.
    • (2012) Brain Res. , vol.1473 , pp. 1-8
    • Gerard, F.1    Hansson, E.2
  • 99
    • 84907253400 scopus 로고    scopus 로고
    • Potent trophic activity of spermidine supramolecular complexes in in vitro models
    • [99] Ghisalberti, C.A., Morisetti, A., Bestetti, A., Cairo, G., Potent trophic activity of spermidine supramolecular complexes in in vitro models. World J. Biol. Chem. 4 (2013), 71–78.
    • (2013) World J. Biol. Chem. , vol.4 , pp. 71-78
    • Ghisalberti, C.A.1    Morisetti, A.2    Bestetti, A.3    Cairo, G.4
  • 100
  • 101
    • 84955439589 scopus 로고    scopus 로고
    • Spermidine-induced improvement of reconsolidation of memory involves calcium-dependent protein kinase in rats
    • [101] Girardi, B.A., Ribeiro, D.A., Signor, C., Muller, M., Gais, M.A., Mello, C.F., Rubin, M.A., Spermidine-induced improvement of reconsolidation of memory involves calcium-dependent protein kinase in rats. Learn. Mem. 23 (2015), 21–28.
    • (2015) Learn. Mem. , vol.23 , pp. 21-28
    • Girardi, B.A.1    Ribeiro, D.A.2    Signor, C.3    Muller, M.4    Gais, M.A.5    Mello, C.F.6    Rubin, M.A.7
  • 102
    • 30844451008 scopus 로고    scopus 로고
    • Glutamate-based therapeutic approaches: NR2B receptor antagonists
    • [102] Gogas, K.R., Glutamate-based therapeutic approaches: NR2B receptor antagonists. Curr. Opin. Pharmacol. 6 (2006), 68–74.
    • (2006) Curr. Opin. Pharmacol. , vol.6 , pp. 68-74
    • Gogas, K.R.1
  • 103
    • 0019807544 scopus 로고
    • Polyamines and antibiotic effects on translation
    • [103] Goldemberg, S.H., Algranati, I.D., Polyamines and antibiotic effects on translation. Med. Biol. 59 (1981), 360–367.
    • (1981) Med. Biol. , vol.59 , pp. 360-367
    • Goldemberg, S.H.1    Algranati, I.D.2
  • 105
    • 84903372759 scopus 로고    scopus 로고
    • Inhibition of the polyamine system counteracts beta-amyloid peptide-induced memory impairment in mice: involvement of extrasynaptic NMDA receptors
    • [105] Gomes, G.M., Dalmolin, G.D., Bar, J., Karpova, A., Mello, C.F., Kreutz, M.R., Rubin, M.A., Inhibition of the polyamine system counteracts beta-amyloid peptide-induced memory impairment in mice: involvement of extrasynaptic NMDA receptors. PLoS One, 9, 2014, e99184.
    • (2014) PLoS One , vol.9 , pp. e99184
    • Gomes, G.M.1    Dalmolin, G.D.2    Bar, J.3    Karpova, A.4    Mello, C.F.5    Kreutz, M.R.6    Rubin, M.A.7
  • 106
    • 84874433307 scopus 로고    scopus 로고
    • Effects of promoter methylation on increased expression of polyamine biosynthetic genes in suicide
    • [106] Gross, J.A., Fiori, L.M., Labonte, B., Lopez, J.P., Turecki, G., Effects of promoter methylation on increased expression of polyamine biosynthetic genes in suicide. J. Psychiatr. Res. 47 (2013), 513–519.
    • (2013) J. Psychiatr. Res. , vol.47 , pp. 513-519
    • Gross, J.A.1    Fiori, L.M.2    Labonte, B.3    Lopez, J.P.4    Turecki, G.5
  • 108
    • 84863304159 scopus 로고    scopus 로고
    • Spermidine-induced improvement of memory involves a cross-talk between protein kinases C and A
    • [108] Guerra, G.P., Mello, C.F., Bochi, G.V., Pazini, A.M., Rosa, M.M., Ferreira, J., Rubin, M.A., Spermidine-induced improvement of memory involves a cross-talk between protein kinases C and A. J. Neurochem. 122 (2012), 363–373.
    • (2012) J. Neurochem. , vol.122 , pp. 363-373
    • Guerra, G.P.1    Mello, C.F.2    Bochi, G.V.3    Pazini, A.M.4    Rosa, M.M.5    Ferreira, J.6    Rubin, M.A.7
  • 110
    • 2442575980 scopus 로고    scopus 로고
    • Polyamines as clinical laboratory tools
    • [110] Gugliucci, A., Polyamines as clinical laboratory tools. Clin. Chim. Acta 344 (2004), 23–35.
    • (2004) Clin. Chim. Acta , vol.344 , pp. 23-35
    • Gugliucci, A.1
  • 111
    • 67349220182 scopus 로고    scopus 로고
    • Behavioral and neurochemical effects of acute putrescine depletion by difluoromethylornithine in rats
    • [111] Gupta, N., Zhang, H., Liu, P., Behavioral and neurochemical effects of acute putrescine depletion by difluoromethylornithine in rats. Neuroscience 161 (2009), 691–706.
    • (2009) Neuroscience , vol.161 , pp. 691-706
    • Gupta, N.1    Zhang, H.2    Liu, P.3
  • 112
    • 80155125095 scopus 로고    scopus 로고
    • Chronic difluoromethylornithine treatment impairs spatial learning and memory in rats
    • [112] Gupta, N., Zhang, H., Liu, P., Chronic difluoromethylornithine treatment impairs spatial learning and memory in rats. Pharmacol. Biochem. Behav. 100 (2012), 464–473.
    • (2012) Pharmacol. Biochem. Behav. , vol.100 , pp. 464-473
    • Gupta, N.1    Zhang, H.2    Liu, P.3
  • 114
    • 84928684146 scopus 로고    scopus 로고
    • Recent development of multifunctional agents as potential drug candidates for the treatment of Alzheimer's disease
    • [114] Guzior, N., Wieckowska, A., Panek, D., Malawska, B., Recent development of multifunctional agents as potential drug candidates for the treatment of Alzheimer's disease. Curr. Med. Chem. 22 (2015), 373–404.
    • (2015) Curr. Med. Chem. , vol.22 , pp. 373-404
    • Guzior, N.1    Wieckowska, A.2    Panek, D.3    Malawska, B.4
  • 116
    • 0019502489 scopus 로고
    • High-affinity uptake of spermine by slices of rat cerebral cortex
    • [116] Harman, R.J., Shaw, G.G., High-affinity uptake of spermine by slices of rat cerebral cortex. J. Neurochem. 36 (1981), 1609–1615.
    • (1981) J. Neurochem. , vol.36 , pp. 1609-1615
    • Harman, R.J.1    Shaw, G.G.2
  • 117
    • 0034864860 scopus 로고    scopus 로고
    • MK-801 induced retrieval, but not acquisition, deficits for passive avoidance conditioning
    • [117] Harrod, S.B., Flint, R.W., Riccio, D.C., MK-801 induced retrieval, but not acquisition, deficits for passive avoidance conditioning. Pharmacol. Biochem. Behav. 69 (2001), 585–593.
    • (2001) Pharmacol. Biochem. Behav. , vol.69 , pp. 585-593
    • Harrod, S.B.1    Flint, R.W.2    Riccio, D.C.3
  • 118
    • 0026595187 scopus 로고
    • Involvement of putrescine in the development of kindled seizure in rats
    • [118] Hayashi, Y., Hattori, Y., Hori, Y., Involvement of putrescine in the development of kindled seizure in rats. J. Neurochem. 58 (1992), 562–566.
    • (1992) J. Neurochem. , vol.58 , pp. 562-566
    • Hayashi, Y.1    Hattori, Y.2    Hori, Y.3
  • 119
    • 0027400249 scopus 로고
    • Increases in brain polyamine concentrations in chemical kindling and single convulsion induced by pentylenetetrazol in rats
    • [119] Hayashi, Y., Hattori, Y., Moriwaki, A., Lu, Y.F., Hori, Y., Increases in brain polyamine concentrations in chemical kindling and single convulsion induced by pentylenetetrazol in rats. Neurosci. Lett. 149 (1993), 63–66.
    • (1993) Neurosci. Lett. , vol.149 , pp. 63-66
    • Hayashi, Y.1    Hattori, Y.2    Moriwaki, A.3    Lu, Y.F.4    Hori, Y.5
  • 121
    • 0029120518 scopus 로고
    • One-session therapist directed exposure vs two forms of manual directed self-exposure in the treatment of spider phobia
    • [121] Hellstrom, K., Ost, L.G., One-session therapist directed exposure vs two forms of manual directed self-exposure in the treatment of spider phobia. Behav. Res. Ther. 33 (1995), 959–965.
    • (1995) Behav. Res. Ther. , vol.33 , pp. 959-965
    • Hellstrom, K.1    Ost, L.G.2
  • 124
    • 0038125588 scopus 로고    scopus 로고
    • Extracellular calcium sensing and signalling
    • [124] Hofer, A.M., Brown, E.M., Extracellular calcium sensing and signalling. Nat. Rev. Mol. Cell Biol. 4 (2003), 530–538.
    • (2003) Nat. Rev. Mol. Cell Biol. , vol.4 , pp. 530-538
    • Hofer, A.M.1    Brown, E.M.2
  • 125
    • 33847166701 scopus 로고
    • Immunocytochemical localization of polyamines in normal and neoplastic cells. Comparisons to the formaldehyde-fluorescamine and o-phthalaldehyde methods
    • [125] Hougaard, D.M., Fujiwara, K., Larsson, L.I., Immunocytochemical localization of polyamines in normal and neoplastic cells. Comparisons to the formaldehyde-fluorescamine and o-phthalaldehyde methods. Histochem. J. 19 (1987), 643–650.
    • (1987) Histochem. J. , vol.19 , pp. 643-650
    • Hougaard, D.M.1    Fujiwara, K.2    Larsson, L.I.3
  • 126
    • 34247207000 scopus 로고    scopus 로고
    • Neuronal growth and survival mediated by eIF5A, a polyamine-modified translation initiation factor
    • [126] Huang, Y., Higginson, D.S., Hester, L., Park, M.H., Snyder, S.H., Neuronal growth and survival mediated by eIF5A, a polyamine-modified translation initiation factor. Proc. Natl. Acad. Sci. U. S. A. 104 (2007), 4194–4199.
    • (2007) Proc. Natl. Acad. Sci. U. S. A. , vol.104 , pp. 4194-4199
    • Huang, Y.1    Higginson, D.S.2    Hester, L.3    Park, M.H.4    Snyder, S.H.5
  • 128
    • 73149118652 scopus 로고    scopus 로고
    • Novel oligoamine analogues inhibit lysine-specific demethylase 1 and induce reexpression of epigenetically silenced genes
    • [128] Huang, Y., Stewart, T.M., Wu, Y., Baylin, S.B., Marton, L.J., Perkins, B., Jones, R.J., Woster, P.M., Casero, R.A. Jr., Novel oligoamine analogues inhibit lysine-specific demethylase 1 and induce reexpression of epigenetically silenced genes. Clin. Cancer Res. 15 (2009), 7217–7228.
    • (2009) Clin. Cancer Res. , vol.15 , pp. 7217-7228
    • Huang, Y.1    Stewart, T.M.2    Wu, Y.3    Baylin, S.B.4    Marton, L.J.5    Perkins, B.6    Jones, R.J.7    Woster, P.M.8    Casero, R.A.9
  • 130
    • 0034685624 scopus 로고    scopus 로고
    • Polyamines: mysterious modulators of cellular functions
    • [130] Igarashi, K., Kashiwagi, K., Polyamines: mysterious modulators of cellular functions. Biochem. Biophys. Res. Commun. 271 (2000), 559–564.
    • (2000) Biochem. Biophys. Res. Commun. , vol.271 , pp. 559-564
    • Igarashi, K.1    Kashiwagi, K.2
  • 132
    • 0026706495 scopus 로고
    • NMDA antagonists make learning and recall state-dependent
    • [132] Jackson, A., Koek, W., Colpaert, F.C., NMDA antagonists make learning and recall state-dependent. Behav. Pharmacol. 3 (1992), 415–421.
    • (1992) Behav. Pharmacol. , vol.3 , pp. 415-421
    • Jackson, A.1    Koek, W.2    Colpaert, F.C.3
  • 133
    • 0000242953 scopus 로고
    • A simple one-trial learning situation for mice
    • [133] Jarvik, M.E., Essman, W.B., A simple one-trial learning situation for mice. Psychol. Rep., 6, 1960, 290.
    • (1960) Psychol. Rep. , vol.6 , pp. 290
    • Jarvik, M.E.1    Essman, W.B.2
  • 134
    • 0242322027 scopus 로고    scopus 로고
    • Regulation of a TRPM7-like current in rat brain microglia
    • [134] Jiang, X., Newell, E.W., Schlichter, L.C., Regulation of a TRPM7-like current in rat brain microglia. J. Biol. Chem. 278 (2003), 42867–42876.
    • (2003) J. Biol. Chem. , vol.278 , pp. 42867-42876
    • Jiang, X.1    Newell, E.W.2    Schlichter, L.C.3
  • 135
    • 0842301316 scopus 로고    scopus 로고
    • Biochemical modulation of NMDA receptors: role in conditioned taste aversion
    • [135] Jimenez, B., Tapia, R., Biochemical modulation of NMDA receptors: role in conditioned taste aversion. Neurochem. Res. 29 (2004), 161–168.
    • (2004) Neurochem. Res. , vol.29 , pp. 161-168
    • Jimenez, B.1    Tapia, R.2
  • 136
    • 0033982377 scopus 로고    scopus 로고
    • Acquisition, extinction, and reinstatement of Pavlovian fear conditioning: the roles of the NMDA receptor and nitric oxide
    • [136] Johnson, D.M., Baker, J.D., Azorlosa, J.L., Acquisition, extinction, and reinstatement of Pavlovian fear conditioning: the roles of the NMDA receptor and nitric oxide. Brain Res. 857 (2000), 66–70.
    • (2000) Brain Res. , vol.857 , pp. 66-70
    • Johnson, D.M.1    Baker, J.D.2    Azorlosa, J.L.3
  • 137
    • 0023689180 scopus 로고
    • Characterization of the inducible polyamine transporter in bovine lymphocytes
    • [137] Kakinuma, Y., Hoshino, K., Igarashi, K., Characterization of the inducible polyamine transporter in bovine lymphocytes. Eur. J. Biochem. 176 (1988), 409–414.
    • (1988) Eur. J. Biochem. , vol.176 , pp. 409-414
    • Kakinuma, Y.1    Hoshino, K.2    Igarashi, K.3
  • 138
    • 0030860597 scopus 로고    scopus 로고
    • Block and modulation of N-methyl-D-aspartate receptors by polyamines and protons: role of amino acid residues in the transmembrane and pore-forming regions of NR1 and NR2 subunits
    • [138] Kashiwagi, K., Pahk, A.J., Masuko, T., Igarashi, K., Williams, K., Block and modulation of N-methyl-D-aspartate receptors by polyamines and protons: role of amino acid residues in the transmembrane and pore-forming regions of NR1 and NR2 subunits. Mol. Pharmacol. 52 (1997), 701–713.
    • (1997) Mol. Pharmacol. , vol.52 , pp. 701-713
    • Kashiwagi, K.1    Pahk, A.J.2    Masuko, T.3    Igarashi, K.4    Williams, K.5
  • 139
    • 84892367121 scopus 로고    scopus 로고
    • Replicated, replicable and relevant-target engagement and pharmacological experimentation in the 21st century
    • [139] Kenakin, T., Bylund, D.B., Toews, M.L., Mullane, K., Winquist, R.J., Williams, M., Replicated, replicable and relevant-target engagement and pharmacological experimentation in the 21st century. Biochem. Pharmacol. 87 (2014), 64–77.
    • (2014) Biochem. Pharmacol. , vol.87 , pp. 64-77
    • Kenakin, T.1    Bylund, D.B.2    Toews, M.L.3    Mullane, K.4    Winquist, R.J.5    Williams, M.6
  • 140
    • 0003007006 scopus 로고
    • Characterization of polyamine transport pathways
    • Carter C Academic Press London
    • [140] Khan, K.A., Quemener, V., Moulinoux, J.P., Characterization of polyamine transport pathways. Carter C, (eds.) Neuropharmacology of Polyamines, 1994, Academic Press, London, 37–60.
    • (1994) Neuropharmacology of Polyamines , pp. 37-60
    • Khan, K.A.1    Quemener, V.2    Moulinoux, J.P.3
  • 142
    • 0032543202 scopus 로고    scopus 로고
    • Spermidine, a polyamine site agonist, attenuates working memory deficits caused by blockade of hippocampal muscarinic receptors and mGluRs in rats
    • [142] Kishi, A., Ohno, M., Watanabe, S., Spermidine, a polyamine site agonist, attenuates working memory deficits caused by blockade of hippocampal muscarinic receptors and mGluRs in rats. Brain Res. 793 (1998), 311–314.
    • (1998) Brain Res. , vol.793 , pp. 311-314
    • Kishi, A.1    Ohno, M.2    Watanabe, S.3
  • 143
    • 0032484065 scopus 로고    scopus 로고
    • Concurrent activation of hippocampal glycine and polyamine sites of the N-methyl-D-aspartate receptor synergistically reverses working memory deficits in rats
    • [143] Kishi, A., Ohno, M., Watanabe, S., Concurrent activation of hippocampal glycine and polyamine sites of the N-methyl-D-aspartate receptor synergistically reverses working memory deficits in rats. Neurosci. Lett. 257 (1998), 131–134.
    • (1998) Neurosci. Lett. , vol.257 , pp. 131-134
    • Kishi, A.1    Ohno, M.2    Watanabe, S.3
  • 145
    • 0025773843 scopus 로고
    • Changes in ingestive behavior induced by intracranial injection of spermine
    • [145] Kohno, H., Sakurada, T., Kisara, K., Changes in ingestive behavior induced by intracranial injection of spermine. J. Pharmacobiodyn. 14 (1991), 407–412.
    • (1991) J. Pharmacobiodyn. , vol.14 , pp. 407-412
    • Kohno, H.1    Sakurada, T.2    Kisara, K.3
  • 146
    • 0016173867 scopus 로고
    • Regulatory effects of polyamines on membrane-bound acetylcholinesterase
    • [146] Kossorotow, A., Wolf, H., Seiler, N., Regulatory effects of polyamines on membrane-bound acetylcholinesterase. Biochem. J. 144 (1974), 21–27.
    • (1974) Biochem. J. , vol.144 , pp. 21-27
    • Kossorotow, A.1    Wolf, H.2    Seiler, N.3
  • 148
    • 34848925535 scopus 로고    scopus 로고
    • Cellular and subcellular rat brain spermidine synthase expression patterns suggest region-specific roles for polyamines, including cerebellar pre-synaptic function
    • [148] Krauss, M., Weiss, T., Langnaese, K., Richter, K., Kowski, A., Veh, R.W., Laube, G., Cellular and subcellular rat brain spermidine synthase expression patterns suggest region-specific roles for polyamines, including cerebellar pre-synaptic function. J. Neurochem. 103 (2007), 679–693.
    • (2007) J. Neurochem. , vol.103 , pp. 679-693
    • Krauss, M.1    Weiss, T.2    Langnaese, K.3    Richter, K.4    Kowski, A.5    Veh, R.W.6    Laube, G.7
  • 149
    • 0041353433 scopus 로고    scopus 로고
    • GABA(B) receptor transduction mechanisms, and cross-talk between protein kinases A and C, in GABAergic terminals synapsing onto neurons of the rat nucleus basalis of Meynert
    • [149] Kubota, H., Katsurabayashi, S., Moorhouse, A.J., Murakami, N., Koga, H., Akaike, N., GABA(B) receptor transduction mechanisms, and cross-talk between protein kinases A and C, in GABAergic terminals synapsing onto neurons of the rat nucleus basalis of Meynert. J. Physiol.-Lond. 551 (2003), 263–276.
    • (2003) J. Physiol.-Lond. , vol.551 , pp. 263-276
    • Kubota, H.1    Katsurabayashi, S.2    Moorhouse, A.J.3    Murakami, N.4    Koga, H.5    Akaike, N.6
  • 150
    • 84918591171 scopus 로고    scopus 로고
    • A review on Alzheimer's disease pathophysiology and its management: an update
    • [150] Kumar, A., Singh, A., Ekavali, A review on Alzheimer's disease pathophysiology and its management: an update. Pharmacol. Rep. 67 (2015), 195–203.
    • (2015) Pharmacol. Rep. , vol.67 , pp. 195-203
    • Kumar, A.1    Singh, A.2    Ekavali3
  • 151
    • 0031964472 scopus 로고    scopus 로고
    • Polyamines may regulate S-phase progression but not the dynamic changes of chromatin during the cell cycle
    • [151] Laitinen, J., Stenius, K., Eloranta, T.O., Holtta, E., Polyamines may regulate S-phase progression but not the dynamic changes of chromatin during the cell cycle. J. Cell. Biochem. 68 (1998), 200–212.
    • (1998) J. Cell. Biochem. , vol.68 , pp. 200-212
    • Laitinen, J.1    Stenius, K.2    Eloranta, T.O.3    Holtta, E.4
  • 152
    • 0022546254 scopus 로고
    • Purification of mouse brain ornithine decarboxylase reveals its presence as an inactive complex with antizyme
    • [152] Laitinen, P.H., Hietala, O.A., Pulkka, A.E., Pajunen, A.E., Purification of mouse brain ornithine decarboxylase reveals its presence as an inactive complex with antizyme. Biochem. J. 236 (1986), 613–616.
    • (1986) Biochem. J. , vol.236 , pp. 613-616
    • Laitinen, P.H.1    Hietala, O.A.2    Pulkka, A.E.3    Pajunen, A.E.4
  • 153
    • 33845620991 scopus 로고    scopus 로고
    • Biological significance of dietary polyamines
    • [153] Larque, E., Sabater-Molina, M., Zamora, S., Biological significance of dietary polyamines. Nutrition 23 (2007), 87–95.
    • (2007) Nutrition , vol.23 , pp. 87-95
    • Larque, E.1    Sabater-Molina, M.2    Zamora, S.3
  • 155
    • 0037128465 scopus 로고    scopus 로고
    • Differential distribution of spermidine/spermine-like immunoreactivity in neurons of the adult rat brain
    • [155] Laube, G., Bernstein, H.G., Wolf, G., Veh, R.W., Differential distribution of spermidine/spermine-like immunoreactivity in neurons of the adult rat brain. J. Comp. Neurol. 444 (2002), 369–386.
    • (2002) J. Comp. Neurol. , vol.444 , pp. 369-386
    • Laube, G.1    Bernstein, H.G.2    Wolf, G.3    Veh, R.W.4
  • 156
    • 32244446966 scopus 로고    scopus 로고
    • A novel protein kinase CK2 substrate indicates CK2 is not directly stimulated by polyamines in vivo
    • [156] Lawson, K., Larentowicz, L., Artim, S., Hayes, C.S., Gilmour, S.K., A novel protein kinase CK2 substrate indicates CK2 is not directly stimulated by polyamines in vivo. Biochemistry 45 (2006), 1499–1510.
    • (2006) Biochemistry , vol.45 , pp. 1499-1510
    • Lawson, K.1    Larentowicz, L.2    Artim, S.3    Hayes, C.S.4    Gilmour, S.K.5
  • 157
    • 53349129897 scopus 로고    scopus 로고
    • Neuro-inflammation induced by lipopolysaccharide causes cognitive impairment through enhancement of beta-amyloid generation
    • [157] Lee, J.W., Lee, Y.K., Yuk, D.Y., Choi, D.Y., Ban, S.B., Oh, K.W., Hong, J.T., Neuro-inflammation induced by lipopolysaccharide causes cognitive impairment through enhancement of beta-amyloid generation. J. Neuroinflammation, 5, 2008, 37.
    • (2008) J. Neuroinflammation , vol.5 , pp. 37
    • Lee, J.W.1    Lee, Y.K.2    Yuk, D.Y.3    Choi, D.Y.4    Ban, S.B.5    Oh, K.W.6    Hong, J.T.7
  • 158
    • 0026545204 scopus 로고
    • Spermine regulates N-methyl-D-aspartate receptor desensitization
    • [158] Lerma, J., Spermine regulates N-methyl-D-aspartate receptor desensitization. Neuron 8 (1992), 343–352.
    • (1992) Neuron , vol.8 , pp. 343-352
    • Lerma, J.1
  • 159
    • 0030861055 scopus 로고    scopus 로고
    • Binding of polyamines to an autonomous domain of the regulatory subunit of protein kinase CK2 induces a conformational change in the holoenzyme. A proposed role for the kinase stimulation
    • [159] Leroy, D., Heriche, J.K., Filhol, O., Chambaz, E.M., Cochet, C., Binding of polyamines to an autonomous domain of the regulatory subunit of protein kinase CK2 induces a conformational change in the holoenzyme. A proposed role for the kinase stimulation. J. Biol. Chem. 272 (1997), 20820–20827.
    • (1997) J. Biol. Chem. , vol.272 , pp. 20820-20827
    • Leroy, D.1    Heriche, J.K.2    Filhol, O.3    Chambaz, E.M.4    Cochet, C.5
  • 161
    • 0000029613 scopus 로고
    • Observationes de Anthonii Leeuwenhoeck, de natis e semine genital aminalculis
    • [161] Lewenhoeck, D.A., Observationes de Anthonii Leeuwenhoeck, de natis e semine genital aminalculis. Phil. Trans. 12 (1677), 1040–1043.
    • (1677) Phil. Trans. , vol.12 , pp. 1040-1043
    • Lewenhoeck, D.A.1
  • 162
    • 84922378140 scopus 로고    scopus 로고
    • Endogenous polyamine function—the RNA perspective
    • [162] Lightfoot, H.L., Hall, J., Endogenous polyamine function—the RNA perspective. Nucleic Acids Res. 42 (2014), 11275–11290.
    • (2014) Nucleic Acids Res. , vol.42 , pp. 11275-11290
    • Lightfoot, H.L.1    Hall, J.2
  • 163
    • 49249086117 scopus 로고    scopus 로고
    • Age-related changes in polyamines in memory-associated brain structures in rats
    • [163] Liu, P., Gupta, N., Jing, Y., Zhang, H., Age-related changes in polyamines in memory-associated brain structures in rats. Neuroscience 155 (2008), 789–796.
    • (2008) Neuroscience , vol.155 , pp. 789-796
    • Liu, P.1    Gupta, N.2    Jing, Y.3    Zhang, H.4
  • 164
    • 77953039089 scopus 로고    scopus 로고
    • Antizyme inhibitor 2: molecular, cellular and physiological aspects
    • [164] Lopez-Contreras, A.J., Ramos-Molina, B., Cremades, A., Penafiel, R., Antizyme inhibitor 2: molecular, cellular and physiological aspects. Amino Acids 38 (2010), 603–611.
    • (2010) Amino Acids , vol.38 , pp. 603-611
    • Lopez-Contreras, A.J.1    Ramos-Molina, B.2    Cremades, A.3    Penafiel, R.4
  • 165
  • 166
    • 0035112495 scopus 로고    scopus 로고
    • Acrolein is increased in Alzheimer's disease brain and is toxic to primary hippocampal cultures
    • [166] Lovell, M.A., Xie, C., Markesbery, W.R., Acrolein is increased in Alzheimer's disease brain and is toxic to primary hippocampal cultures. Neurobiol. Aging 22 (2001), 187–194.
    • (2001) Neurobiol. Aging , vol.22 , pp. 187-194
    • Lovell, M.A.1    Xie, C.2    Markesbery, W.R.3
  • 167
    • 4644370761 scopus 로고    scopus 로고
    • Cognitive processes in extinction
    • [167] Lovibond, P.F., Cognitive processes in extinction. Learn. Mem. 11 (2004), 495–500.
    • (2004) Learn. Mem. , vol.11 , pp. 495-500
    • Lovibond, P.F.1
  • 168
    • 0032916347 scopus 로고    scopus 로고
    • Blockade of a retinal cGMP-gated channel by polyamines
    • [168] Lu, Z., Ding, L., Blockade of a retinal cGMP-gated channel by polyamines. J. Gen. Physiol. 113 (1999), 35–43.
    • (1999) J. Gen. Physiol. , vol.113 , pp. 35-43
    • Lu, Z.1    Ding, L.2
  • 169
    • 80054823126 scopus 로고    scopus 로고
    • Ifenprodil restores GDNF-evoked Ca(2+) signalling and Na(+)/K(+)-ATPase expression in inflammation-pretreated astrocytes
    • [169] Lundborg, C., Westerlund, A., Bjorklund, U., Biber, B., Hansson, E., Ifenprodil restores GDNF-evoked Ca(2+) signalling and Na(+)/K(+)-ATPase expression in inflammation-pretreated astrocytes. J. Neurochem. 119 (2011), 686–696.
    • (2011) J. Neurochem. , vol.119 , pp. 686-696
    • Lundborg, C.1    Westerlund, A.2    Bjorklund, U.3    Biber, B.4    Hansson, E.5
  • 170
    • 0032838959 scopus 로고    scopus 로고
    • Rectification of the olfactory cyclic nucleotide-gated channel by intracellular polyamines
    • [170] Lynch, J.W., Rectification of the olfactory cyclic nucleotide-gated channel by intracellular polyamines. J. Memb. Biol. 170 (1999), 213–227.
    • (1999) J. Memb. Biol. , vol.170 , pp. 213-227
    • Lynch, J.W.1
  • 171
    • 84900470858 scopus 로고    scopus 로고
    • Chronic brain inflammation causes a reduction in GluN2A and GluN2B subunits of NMDA receptors and an increase in the phosphorylation of mitogen-activated protein kinases in the hippocampus
    • [171] Ma, J., Choi, B.R., Chung, C., Min, S.S., Jeon, W.K., Han, J.S., Chronic brain inflammation causes a reduction in GluN2A and GluN2B subunits of NMDA receptors and an increase in the phosphorylation of mitogen-activated protein kinases in the hippocampus. Mol. Brain, 7, 2014, 33.
    • (2014) Mol. Brain , vol.7 , pp. 33
    • Ma, J.1    Choi, B.R.2    Chung, C.3    Min, S.S.4    Jeon, W.K.5    Han, J.S.6
  • 172
    • 84871046431 scopus 로고    scopus 로고
    • Cation-pi interaction: its role and relevance in chemistry, biology, and material science
    • [172] Mahadevi, A.S., Sastry, G.N., Cation-pi interaction: its role and relevance in chemistry, biology, and material science. Chem. Rev. 113 (2013), 2100–2138.
    • (2013) Chem. Rev. , vol.113 , pp. 2100-2138
    • Mahadevi, A.S.1    Sastry, G.N.2
  • 173
    • 84910048025 scopus 로고    scopus 로고
    • Overexpression of NMDAR2B in an inflammatory model of Alzheimer's disease: modulation by NOS inhibitors
    • [173] Maher, A., El-Sayed, N.S., Breitinger, H.G., Gad, M.Z., Overexpression of NMDAR2B in an inflammatory model of Alzheimer's disease: modulation by NOS inhibitors. Brain Res. Bull. 109 (2014), 109–116.
    • (2014) Brain Res. Bull. , vol.109 , pp. 109-116
    • Maher, A.1    El-Sayed, N.S.2    Breitinger, H.G.3    Gad, M.Z.4
  • 175
    • 0034927082 scopus 로고    scopus 로고
    • Neurobiology of Pavlovian fear conditioning
    • [175] Maren, S., Neurobiology of Pavlovian fear conditioning. Annu. Rev. Neurosci. 24 (2001), 897–931.
    • (2001) Annu. Rev. Neurosci. , vol.24 , pp. 897-931
    • Maren, S.1
  • 180
    • 0031844699 scopus 로고    scopus 로고
    • Nitric oxide synthases: catalytic function and progress towards selective inhibition
    • [180] Mayer, B., Andrew, P., Nitric oxide synthases: catalytic function and progress towards selective inhibition. Naunyn Schmiedeberg Arch. Pharmacol. 358 (1998), 127–133.
    • (1998) Naunyn Schmiedeberg Arch. Pharmacol. , vol.358 , pp. 127-133
    • Mayer, B.1    Andrew, P.2
  • 181
    • 84964300287 scopus 로고    scopus 로고
    • Consolidating memories
    • [181] McGaugh, J.L., Consolidating memories. Annu. Rev. Psychol. 66 (2015), 1–24.
    • (2015) Annu. Rev. Psychol. , vol.66 , pp. 1-24
    • McGaugh, J.L.1
  • 182
    • 0036881442 scopus 로고    scopus 로고
    • Amygdala modulation of memory consolidation: interaction with other brain systems
    • [182] McGaugh, J.L., McIntyre, C.K., Power, A.E., Amygdala modulation of memory consolidation: interaction with other brain systems. Neurobiol. Learn. Mem. 78 (2002), 539–552.
    • (2002) Neurobiol. Learn. Mem. , vol.78 , pp. 539-552
    • McGaugh, J.L.1    McIntyre, C.K.2    Power, A.E.3
  • 183
    • 0025694769 scopus 로고
    • Polyamines potentiate responses of N-methyl-D-aspartate receptors expressed in xenopus oocytes
    • [183] McGurk, J.F., Bennett, M.V., Zukin, R.S., Polyamines potentiate responses of N-methyl-D-aspartate receptors expressed in xenopus oocytes. Proc. Natl. Acad. Sci. U. S. A. 87 (1990), 9971–9974.
    • (1990) Proc. Natl. Acad. Sci. U. S. A. , vol.87 , pp. 9971-9974
    • McGurk, J.F.1    Bennett, M.V.2    Zukin, R.S.3
  • 184
    • 44549088590 scopus 로고    scopus 로고
    • Do memories consolidate to persist or do they persist to consolidate?
    • [184] Medina, J.H., Bekinschtein, P., Cammarota, M., Izquierdo, I., Do memories consolidate to persist or do they persist to consolidate?. Behav. Brain Res. 192 (2008), 61–69.
    • (2008) Behav. Brain Res. , vol.192 , pp. 61-69
    • Medina, J.H.1    Bekinschtein, P.2    Cammarota, M.3    Izquierdo, I.4
  • 185
    • 77955904672 scopus 로고    scopus 로고
    • Polyamines in drug discovery: from the universal template approach to the multitarget-directed ligand design strategy
    • [185] Melchiorre, C., Bolognesi, M.L., Minarini, A., Rosini, M., Tumiatti, V., Polyamines in drug discovery: from the universal template approach to the multitarget-directed ligand design strategy. J. Med. Chem. 53 (2010), 5906–5914.
    • (2010) J. Med. Chem. , vol.53 , pp. 5906-5914
    • Melchiorre, C.1    Bolognesi, M.L.2    Minarini, A.3    Rosini, M.4    Tumiatti, V.5
  • 187
    • 0031962873 scopus 로고    scopus 로고
    • Combined stimulation of the glycine and polyamine sites of the NMDA receptor attenuates NMDA blockade-induced learning deficits of rats in a 14-unit T-maze
    • [187] Meyer, R.C., Knox, J., Purwin, D.A., Spangler, E.L., Ingram, D.K., Combined stimulation of the glycine and polyamine sites of the NMDA receptor attenuates NMDA blockade-induced learning deficits of rats in a 14-unit T-maze. Psychopharmacology (Berl) 135 (1998), 290–295.
    • (1998) Psychopharmacology (Berl) , vol.135 , pp. 290-295
    • Meyer, R.C.1    Knox, J.2    Purwin, D.A.3    Spangler, E.L.4    Ingram, D.K.5
  • 189
  • 190
    • 84944278561 scopus 로고    scopus 로고
    • Remaining mysteries of molecular biology: the role of polyamines in the cell
    • [190] Miller-Fleming, L., Olin-Sandoval, V., Campbell, K., Ralser, M., Remaining mysteries of molecular biology: the role of polyamines in the cell. J. Mol. Biol. 427 (2015), 3389–3406.
    • (2015) J. Mol. Biol. , vol.427 , pp. 3389-3406
    • Miller-Fleming, L.1    Olin-Sandoval, V.2    Campbell, K.3    Ralser, M.4
  • 192
    • 0014401739 scopus 로고
    • Retrograde amnesia produced by electroconvulsive shock after reactivation of a consolidated memory trace
    • [192] Misanin, J.R., Miller, R.R., Lewis, D.J., Retrograde amnesia produced by electroconvulsive shock after reactivation of a consolidated memory trace. Science 160 (1968), 554–555.
    • (1968) Science , vol.160 , pp. 554-555
    • Misanin, J.R.1    Miller, R.R.2    Lewis, D.J.3
  • 193
    • 15344340623 scopus 로고    scopus 로고
    • Polyamines: metabolism and implications in human diseases
    • [193] Moinard, C., Cynober, L., de Bandt, J.P., Polyamines: metabolism and implications in human diseases. Clin. Nutr. 24 (2005), 184–197.
    • (2005) Clin. Nutr. , vol.24 , pp. 184-197
    • Moinard, C.1    Cynober, L.2    de Bandt, J.P.3
  • 194
    • 84856492820 scopus 로고    scopus 로고
    • Agmatine (decarboxylated -arginine): physiological role and therapeutic potential
    • [194] Molderings, G.J., Haenisch, B., Agmatine (decarboxylated -arginine): physiological role and therapeutic potential. Pharmacol. Ther. 133 (2012), 351–365.
    • (2012) Pharmacol. Ther. , vol.133 , pp. 351-365
    • Molderings, G.J.1    Haenisch, B.2
  • 195
    • 79961020657 scopus 로고    scopus 로고
    • Molecular basis of positive allosteric modulation of GluN2B NMDA receptors by polyamines
    • [195] Mony, L., Zhu, S., Carvalho, S., Paoletti, P., Molecular basis of positive allosteric modulation of GluN2B NMDA receptors by polyamines. EMBO J. 30 (2011), 3134–3146.
    • (2011) EMBO J. , vol.30 , pp. 3134-3146
    • Mony, L.1    Zhu, S.2    Carvalho, S.3    Paoletti, P.4
  • 197
  • 198
    • 0024455878 scopus 로고
    • Synaptic plasticity and learning: selective impairment of learning rats and blockade of long-term potentiation in vivo by the N-methyl-D-aspartate receptor antagonist AP5
    • [198] Morris, R.G., Synaptic plasticity and learning: selective impairment of learning rats and blockade of long-term potentiation in vivo by the N-methyl-D-aspartate receptor antagonist AP5. J. Neurosci. 9 (1989), 3040–3057.
    • (1989) J. Neurosci. , vol.9 , pp. 3040-3057
    • Morris, R.G.1
  • 199
    • 0005535917 scopus 로고
    • Spatial localization does not require the presence of local cues
    • [199] Morris, R.G.M., Spatial localization does not require the presence of local cues. Learn. Motiv. 12 (1981), 239–260.
    • (1981) Learn. Motiv. , vol.12 , pp. 239-260
    • Morris, R.G.M.1
  • 200
    • 0029051691 scopus 로고
    • Brain polyamine levels are altered in Alzheimer's disease
    • [200] Morrison, L.D., Kish, S.J., Brain polyamine levels are altered in Alzheimer's disease. Neurosci. Lett. 197 (1995), 5–8.
    • (1995) Neurosci. Lett. , vol.197 , pp. 5-8
    • Morrison, L.D.1    Kish, S.J.2
  • 201
    • 0031812234 scopus 로고    scopus 로고
    • Ornithine decarboxylase in human brain: influence of aging, regional distribution, and Alzheimer's disease
    • [201] Morrison, L.D., Cao, X.C., Kish, S.J., Ornithine decarboxylase in human brain: influence of aging, regional distribution, and Alzheimer's disease. J. Neurochem. 71 (1998), 288–294.
    • (1998) J. Neurochem. , vol.71 , pp. 288-294
    • Morrison, L.D.1    Cao, X.C.2    Kish, S.J.3
  • 202
    • 0037443043 scopus 로고    scopus 로고
    • Subunit-dependent modulation of kainate receptors by extracellular protons and polyamines
    • [202] Mott, D.D., Washburn, M.S., Zhang, S., Dingledine, R.J., Subunit-dependent modulation of kainate receptors by extracellular protons and polyamines. J. Neurosci. 23 (2003), 1179–1188.
    • (2003) J. Neurosci. , vol.23 , pp. 1179-1188
    • Mott, D.D.1    Washburn, M.S.2    Zhang, S.3    Dingledine, R.J.4
  • 203
    • 0034571503 scopus 로고    scopus 로고
    • The labile nature of consolidation theory
    • [203] Nader, K., Schafe, G.E., LeDoux, J.E., The labile nature of consolidation theory. Nat. Rev. Neurosci. 1 (2000), 216–219.
    • (2000) Nat. Rev. Neurosci. , vol.1 , pp. 216-219
    • Nader, K.1    Schafe, G.E.2    LeDoux, J.E.3
  • 204
    • 0034680134 scopus 로고    scopus 로고
    • Fear memories require protein synthesis in the amygdala for reconsolidation after retrieval
    • [204] Nader, K., Schafe, G.E., Le doux, J.E., Fear memories require protein synthesis in the amygdala for reconsolidation after retrieval. Nature 406 (2000), 722–726.
    • (2000) Nature , vol.406 , pp. 722-726
    • Nader, K.1    Schafe, G.E.2    Le doux, J.E.3
  • 205
    • 0027763343 scopus 로고
    • Polyamines modulate streptomycin-induced mistranslation in Escherichia coli
    • [205] Nastri, H.G., Fastame, I.G., Algranati, I.D., Polyamines modulate streptomycin-induced mistranslation in Escherichia coli. Biochim. Biophys. Acta 1216 (1993), 455–459.
    • (1993) Biochim. Biophys. Acta , vol.1216 , pp. 455-459
    • Nastri, H.G.1    Fastame, I.G.2    Algranati, I.D.3
  • 207
    • 0021958064 scopus 로고
    • On how passive is inhibitory avoidance
    • [207] Netto, C.A., Izquierdo, I., On how passive is inhibitory avoidance. Behav. Neural Biol. 43 (1985), 327–330.
    • (1985) Behav. Neural Biol. , vol.43 , pp. 327-330
    • Netto, C.A.1    Izquierdo, I.2
  • 208
    • 0025898392 scopus 로고
    • Retrieval effects of beta-endorphin and naloxone, and the novelty-induced antinociception in the developing rat
    • [208] Netto, C.A., Maltchik, M., Retrieval effects of beta-endorphin and naloxone, and the novelty-induced antinociception in the developing rat. Behav. Neural Biol. 55 (1991), 366–379.
    • (1991) Behav. Neural Biol. , vol.55 , pp. 366-379
    • Netto, C.A.1    Maltchik, M.2
  • 209
    • 0026325942 scopus 로고
    • Tests of the roles of two diffusible substances in long-term potentiation: evidence for nitric oxide as a possible early retrograde messenger
    • [209] O'Dell, T.J., Hawkins, R.D., Kandel, E.R., Arancio, O., Tests of the roles of two diffusible substances in long-term potentiation: evidence for nitric oxide as a possible early retrograde messenger. Proc. Natl. Acad. Sci. U. S. A. 88 (1991), 11285–11289.
    • (1991) Proc. Natl. Acad. Sci. U. S. A. , vol.88 , pp. 11285-11289
    • O'Dell, T.J.1    Hawkins, R.D.2    Kandel, E.R.3    Arancio, O.4
  • 210
    • 0031957666 scopus 로고    scopus 로고
    • Interaction of permeant and blocking ions in cloned inward-rectifier K+ channels
    • [210] Oliver, D., Hahn, H., Antz, C., Ruppersberg, J.P., Fakler, B., Interaction of permeant and blocking ions in cloned inward-rectifier K+ channels. Biophys. J. 74 (1998), 2318–2326.
    • (1998) Biophys. J. , vol.74 , pp. 2318-2326
    • Oliver, D.1    Hahn, H.2    Antz, C.3    Ruppersberg, J.P.4    Fakler, B.5
  • 211
    • 84944552997 scopus 로고    scopus 로고
    • New insights on astrocyte ion channels: critical for homeostasis and neuron-glia signaling
    • [211] Olsen, M.L., Khakh, B.S., Skatchkov, S.N., Zhou, M., Lee, C.J., Rouach, N., New insights on astrocyte ion channels: critical for homeostasis and neuron-glia signaling. J. Neurosci. 35 (2015), 13827–13835.
    • (2015) J. Neurosci. , vol.35 , pp. 13827-13835
    • Olsen, M.L.1    Khakh, B.S.2    Skatchkov, S.N.3    Zhou, M.4    Lee, C.J.5    Rouach, N.6
  • 212
    • 84864380003 scopus 로고    scopus 로고
    • Neural and cellular mechanisms of fear and extinction memory formation
    • [212] Orsini, C.A., Maren, S., Neural and cellular mechanisms of fear and extinction memory formation. Neurosci. Biobehav. Rev. 36 (2012), 1773–1802.
    • (2012) Neurosci. Biobehav. Rev. , vol.36 , pp. 1773-1802
    • Orsini, C.A.1    Maren, S.2
  • 213
    • 4744371427 scopus 로고    scopus 로고
    • Structural analysis of DNA interactions with biogenic polyamines and cobalt(III)hexamine studied by Fourier transform infrared and capillary electrophoresis
    • [213] Ouameur, A.A., Tajmir-Riahi, H.A., Structural analysis of DNA interactions with biogenic polyamines and cobalt(III)hexamine studied by Fourier transform infrared and capillary electrophoresis. J. Biol. Chem. 279 (2004), 42041–42054.
    • (2004) J. Biol. Chem. , vol.279 , pp. 42041-42054
    • Ouameur, A.A.1    Tajmir-Riahi, H.A.2
  • 214
    • 0042304829 scopus 로고
    • State-dependent or dissociated learning produced with pentobarbital
    • [214] Overton, D.A., State-dependent or dissociated learning produced with pentobarbital. J. Comp. Physiol. Psychol. 57 (1964), 3–12.
    • (1964) J. Comp. Physiol. Psychol. , vol.57 , pp. 3-12
    • Overton, D.A.1
  • 215
    • 0030593927 scopus 로고    scopus 로고
    • Differential effects of agents acting at various sites of the NMDA receptor complex in a place preference conditioning model
    • [215] Papp, M., Moryl, E., Maccecchini, M.L., Differential effects of agents acting at various sites of the NMDA receptor complex in a place preference conditioning model. Eur. J. Pharmacol. 317 (1996), 191–196.
    • (1996) Eur. J. Pharmacol. , vol.317 , pp. 191-196
    • Papp, M.1    Moryl, E.2    Maccecchini, M.L.3
  • 216
    • 77953039922 scopus 로고    scopus 로고
    • Functional significance of eIF5A and its hypusine modification in eukaryotes
    • [216] Park, M.H., Nishimura, K., Zanelli, C.F., Valentini, S.R., Functional significance of eIF5A and its hypusine modification in eukaryotes. Amino Acids 38 (2010), 491–500.
    • (2010) Amino Acids , vol.38 , pp. 491-500
    • Park, M.H.1    Nishimura, K.2    Zanelli, C.F.3    Valentini, S.R.4
  • 217
    • 84896316506 scopus 로고    scopus 로고
    • Chromatin remodeling by polyamines and polyamine analogs
    • [217] Pasini, A., Caldarera, C.M., Giordano, E., Chromatin remodeling by polyamines and polyamine analogs. Amino Acids 46 (2014), 595–603.
    • (2014) Amino Acids , vol.46 , pp. 595-603
    • Pasini, A.1    Caldarera, C.M.2    Giordano, E.3
  • 218
    • 70350780368 scopus 로고    scopus 로고
    • Mammalian polyamine metabolism and function
    • [218] Pegg, A.E., Mammalian polyamine metabolism and function. IUBMB Life 61 (2009), 880–894.
    • (2009) IUBMB Life , vol.61 , pp. 880-894
    • Pegg, A.E.1
  • 219
    • 77449159833 scopus 로고    scopus 로고
    • S-Adenosylmethionine decarboxylase
    • [219] Pegg, A.E., S-Adenosylmethionine decarboxylase. Essays Biochem. 46 (2009), 25–45.
    • (2009) Essays Biochem. , vol.46 , pp. 25-45
    • Pegg, A.E.1
  • 220
    • 84890459089 scopus 로고    scopus 로고
    • Toxicity of polyamines and their metabolic products
    • [220] Pegg, A.E., Toxicity of polyamines and their metabolic products. Chem. Res. Toxicol. 26 (2013), 1782–1800.
    • (2013) Chem. Res. Toxicol. , vol.26 , pp. 1782-1800
    • Pegg, A.E.1
  • 222
    • 79956224419 scopus 로고    scopus 로고
    • Current status of the polyamine research field
    • [222] Pegg, A.E., Casero, R.A., Current status of the polyamine research field. Methods Mol. Biol. (Clifton, NJ) 720 (2011), 3–35.
    • (2011) Methods Mol. Biol. (Clifton, NJ) , vol.720 , pp. 3-35
    • Pegg, A.E.1    Casero, R.A.2
  • 223
    • 84909638832 scopus 로고    scopus 로고
    • Anisomycin administered in the olfactory bulb and dorsal hippocampus impaired social recognition memory consolidation in different time-points
    • [223] Pena, R.R., Pereira-Caixeta, A.R., Moraes, M.F., Pereira, G.S., Anisomycin administered in the olfactory bulb and dorsal hippocampus impaired social recognition memory consolidation in different time-points. Brain Res. Bull. 109 (2014), 151–157.
    • (2014) Brain Res. Bull. , vol.109 , pp. 151-157
    • Pena, R.R.1    Pereira-Caixeta, A.R.2    Moraes, M.F.3    Pereira, G.S.4
  • 224
    • 84887433975 scopus 로고    scopus 로고
    • Spermidine stimulates T cell protein-tyrosine phosphatase-mediated protection of intestinal epithelial barrier function
    • [224] Penrose, H.M., Marchelletta, R.R., Krishnan, M., McCole, D.F., Spermidine stimulates T cell protein-tyrosine phosphatase-mediated protection of intestinal epithelial barrier function. J. Biol. Chem. 288 (2013), 32651–32662.
    • (2013) J. Biol. Chem. , vol.288 , pp. 32651-32662
    • Penrose, H.M.1    Marchelletta, R.R.2    Krishnan, M.3    McCole, D.F.4
  • 225
    • 77958153301 scopus 로고    scopus 로고
    • Gating and permeation of kainate receptors: differences unveiled
    • [225] Perrais, D., Veran, J., Mulle, C., Gating and permeation of kainate receptors: differences unveiled. Trends Pharmacol. Sci. 31 (2010), 516–522.
    • (2010) Trends Pharmacol. Sci. , vol.31 , pp. 516-522
    • Perrais, D.1    Veran, J.2    Mulle, C.3
  • 226
    • 0018319269 scopus 로고
    • Effects of physostigmine and lecithin on memory in Alzheimer disease
    • [226] Peters, B.H., Levin, H.S., Effects of physostigmine and lecithin on memory in Alzheimer disease. Ann. Neurol. 6 (1979), 219–221.
    • (1979) Ann. Neurol. , vol.6 , pp. 219-221
    • Peters, B.H.1    Levin, H.S.2
  • 227
  • 228
    • 84939944436 scopus 로고    scopus 로고
    • Effect of morphine on the persistence of long-term memory in rats
    • [228] Porto, G.P., Milanesi, L.H., Rubin, M.A., Mello, C.F., Effect of morphine on the persistence of long-term memory in rats. Psychopharmacology (Berl) 232 (2015), 1747–1753.
    • (2015) Psychopharmacology (Berl) , vol.232 , pp. 1747-1753
    • Porto, G.P.1    Milanesi, L.H.2    Rubin, M.A.3    Mello, C.F.4
  • 229
    • 0034743758 scopus 로고    scopus 로고
    • Role of Ca2+-stimulated adenylyl cyclases in LTP and memory formation
    • [229] Poser, S., Storm, D.R., Role of Ca2+-stimulated adenylyl cyclases in LTP and memory formation. Int. J. Dev. Neurosci. 19 (2001), 387–394.
    • (2001) Int. J. Dev. Neurosci. , vol.19 , pp. 387-394
    • Poser, S.1    Storm, D.R.2
  • 230
    • 0035101782 scopus 로고    scopus 로고
    • Nitric oxide as modulator of neuronal function
    • [230] Prast, H., Philippu, A., Nitric oxide as modulator of neuronal function. Prog. Neurobiol. 64 (2001), 51–68.
    • (2001) Prog. Neurobiol. , vol.64 , pp. 51-68
    • Prast, H.1    Philippu, A.2
  • 231
    • 36049044225 scopus 로고    scopus 로고
    • Animal models of Huntington's disease
    • [231] Ramaswamy, S., McBride, J.L., Kordower, J.H., Animal models of Huntington's disease. ILAR J. 48 (2007), 356–373.
    • (2007) ILAR J. , vol.48 , pp. 356-373
    • Ramaswamy, S.1    McBride, J.L.2    Kordower, J.H.3
  • 232
    • 0023820777 scopus 로고
    • Cooperative modulation of [3H]MK-801 binding to the N-methyl-D-aspartate receptor-ion channel complex by L-glutamate, glycine, and polyamines
    • [232] Ransom, R.W., Stec, N.L., Cooperative modulation of [3H]MK-801 binding to the N-methyl-D-aspartate receptor-ion channel complex by L-glutamate, glycine, and polyamines. J. Neurochem. 51 (1988), 830–836.
    • (1988) J. Neurochem. , vol.51 , pp. 830-836
    • Ransom, R.W.1    Stec, N.L.2
  • 233
    • 0025273293 scopus 로고
    • Arcaine is a competitive antagonist of the polyamine site on the NMDA receptor
    • [233] Reynolds, I.J., Arcaine is a competitive antagonist of the polyamine site on the NMDA receptor. Eur. J. Pharmacol. 177 (1990), 215–216.
    • (1990) Eur. J. Pharmacol. , vol.177 , pp. 215-216
    • Reynolds, I.J.1
  • 234
    • 0025598847 scopus 로고
    • Arcaine uncovers dual interactions of polyamines with the N-methyl-D-aspartate receptor
    • [234] Reynolds, I.J., Arcaine uncovers dual interactions of polyamines with the N-methyl-D-aspartate receptor. J. Pharmacol. Exp. Ther. 255 (1990), 1001–1007.
    • (1990) J. Pharmacol. Exp. Ther. , vol.255 , pp. 1001-1007
    • Reynolds, I.J.1
  • 235
    • 84878177964 scopus 로고    scopus 로고
    • Polyaminergic agents modulate the reconsolidation of conditioned fear
    • [235] Ribeiro, D.A., Mello, C.F., Signor, C., Rubin, M.A., Polyaminergic agents modulate the reconsolidation of conditioned fear. Neurobiol. Learn. Mem. 104 (2013), 9–15.
    • (2013) Neurobiol. Learn. Mem. , vol.104 , pp. 9-15
    • Ribeiro, D.A.1    Mello, C.F.2    Signor, C.3    Rubin, M.A.4
  • 236
    • 33750731675 scopus 로고    scopus 로고
    • 100 years and counting: Prospects for defeating Alzheimer's disease
    • [236] Roberson, E.D., Mucke, L., 100 years and counting: Prospects for defeating Alzheimer's disease. Science 314 (2006), 781–784.
    • (2006) Science , vol.314 , pp. 781-784
    • Roberson, E.D.1    Mucke, L.2
  • 238
    • 0026597543 scopus 로고
    • The polyamine spermine has multiple actions on N-methyl-D-aspartate receptor single-channel currents in cultured cortical neurons
    • [238] Rock, D.M., Macdonald, R.L., The polyamine spermine has multiple actions on N-methyl-D-aspartate receptor single-channel currents in cultured cortical neurons. Mol. Pharmacol. 41 (1992), 83–88.
    • (1992) Mol. Pharmacol. , vol.41 , pp. 83-88
    • Rock, D.M.1    Macdonald, R.L.2
  • 239
    • 0035449320 scopus 로고    scopus 로고
    • Intra-amygdala blockade of the NR2B subunit of the NMDA receptor disrupts the acquisition but not the expression of fear conditioning
    • [239] Rodrigues, S.M., Schafe, G.E., LeDoux, J.E., Intra-amygdala blockade of the NR2B subunit of the NMDA receptor disrupts the acquisition but not the expression of fear conditioning. J. Neurosci. 21 (2001), 6889–6896.
    • (2001) J. Neurosci. , vol.21 , pp. 6889-6896
    • Rodrigues, S.M.1    Schafe, G.E.2    LeDoux, J.E.3
  • 241
    • 84155189480 scopus 로고    scopus 로고
    • Memory consolidation
    • G.F. Koob M. Le Moal R.F. Thompson Academic Press Oxford
    • [241] Roesler, R., McGaugh, J.L., Memory consolidation. Koob, G.F., Le Moal, M., Thompson, R.F., (eds.) Encyclopedia of Behavioral Neuroscience, 2010, Academic Press, Oxford, 206–214.
    • (2010) Encyclopedia of Behavioral Neuroscience , pp. 206-214
    • Roesler, R.1    McGaugh, J.L.2
  • 242
    • 0037728703 scopus 로고    scopus 로고
    • Differential involvement of hippocampal and amygdalar NMDA receptors in contextual and aversive aspects of inhibitory avoidance memory in rats
    • [242] Roesler, R., Schroder, N., Vianna, M.R., Quevedo, J., Bromberg, E., Kapczinski, F., Ferreira, M.B., Differential involvement of hippocampal and amygdalar NMDA receptors in contextual and aversive aspects of inhibitory avoidance memory in rats. Brain Res. 975 (2003), 207–213.
    • (2003) Brain Res. , vol.975 , pp. 207-213
    • Roesler, R.1    Schroder, N.2    Vianna, M.R.3    Quevedo, J.4    Bromberg, E.5    Kapczinski, F.6    Ferreira, M.B.7
  • 243
    • 28944437542 scopus 로고    scopus 로고
    • NMDA receptors mediate consolidation of contextual memory in the hippocampus after context preexposure
    • [243] Roesler, R., Reolon, G.K., Luft, T., Martins, M.R., Schroder, N., Vianna, M.R., Quevedo, J., NMDA receptors mediate consolidation of contextual memory in the hippocampus after context preexposure. Neurochem. Res. 30 (2005), 1407–1411.
    • (2005) Neurochem. Res. , vol.30 , pp. 1407-1411
    • Roesler, R.1    Reolon, G.K.2    Luft, T.3    Martins, M.R.4    Schroder, N.5    Vianna, M.R.6    Quevedo, J.7
  • 245
    • 84856386376 scopus 로고    scopus 로고
    • The polyamine inhibitor alpha-difluoromethylornithine modulates hippocampus-dependent function after single and combined injuries
    • [245] Rosi, S., Ferguson, R., Fishman, K., Allen, A., Raber, J., Fike, J.R., The polyamine inhibitor alpha-difluoromethylornithine modulates hippocampus-dependent function after single and combined injuries. PLoS One, 7, 2012, e31094.
    • (2012) PLoS One , vol.7 , pp. e31094
    • Rosi, S.1    Ferguson, R.2    Fishman, K.3    Allen, A.4    Raber, J.5    Fike, J.R.6
  • 246
    • 58549116306 scopus 로고    scopus 로고
    • Difluoromethylornithine (DFMO) reduces deficits in isolation-induced ultrasonic vocalizations and balance following neonatal ethanol exposure in rats
    • [246] Rubin, M.A., Wellmann, K.A., Lewis, B., Overgaauw, B.J., Littleton, J.M., Barron, S., Difluoromethylornithine (DFMO) reduces deficits in isolation-induced ultrasonic vocalizations and balance following neonatal ethanol exposure in rats. Pharmacol. Biochem. Behav. 92 (2009), 44–50.
    • (2009) Pharmacol. Biochem. Behav. , vol.92 , pp. 44-50
    • Rubin, M.A.1    Wellmann, K.A.2    Lewis, B.3    Overgaauw, B.J.4    Littleton, J.M.5    Barron, S.6
  • 250
    • 0025273692 scopus 로고
    • Characterization of the stimulatory and inhibitory effects of polyamines on [3H]N-(1-[thienyl]cyclohexyl) piperidine binding to the N-methyl-D-aspartate receptor ionophore complex
    • [250] Sacaan, A.I., Johnson, K.M., Characterization of the stimulatory and inhibitory effects of polyamines on [3H]N-(1-[thienyl]cyclohexyl) piperidine binding to the N-methyl-D-aspartate receptor ionophore complex. Mol. Pharmacol. 37 (1990), 572–577.
    • (1990) Mol. Pharmacol. , vol.37 , pp. 572-577
    • Sacaan, A.I.1    Johnson, K.M.2
  • 251
    • 0016352997 scopus 로고
    • Changes in emotional behavior, spontaneous motor activity and brain polyamine levels following bilateral olfactory bulb ablations in mice
    • [251] Sakurada, T., Tadano, T., Imai, M., Kisara, K., Changes in emotional behavior, spontaneous motor activity and brain polyamine levels following bilateral olfactory bulb ablations in mice. Folia Pharmacol. Jpn. 70 (1974), 629–636.
    • (1974) Folia Pharmacol. Jpn. , vol.70 , pp. 629-636
    • Sakurada, T.1    Tadano, T.2    Imai, M.3    Kisara, K.4
  • 252
    • 0034569364 scopus 로고    scopus 로고
    • Strengthening the shaky trace through retrieval
    • [252] Sara, S.J., Strengthening the shaky trace through retrieval. Nat. Rev. Neurosci. 1 (2000), 212–213.
    • (2000) Nat. Rev. Neurosci. , vol.1 , pp. 212-213
    • Sara, S.J.1
  • 253
    • 0034001627 scopus 로고    scopus 로고
    • Retrieval and reconsolidation: toward a neurobiology of remembering
    • [253] Sara, S.J., Retrieval and reconsolidation: toward a neurobiology of remembering. Learn. Mem. 7 (2000), 73–84.
    • (2000) Learn. Mem. , vol.7 , pp. 73-84
    • Sara, S.J.1
  • 254
    • 0029789277 scopus 로고    scopus 로고
    • Agmatinase activity in rat brain: a metabolic pathway for the degradation of agmatine
    • [254] Sastre, M., Regunathan, S., Galea, E., Reis, D.J., Agmatinase activity in rat brain: a metabolic pathway for the degradation of agmatine. J. Neurochem. 67 (1996), 1761–1765.
    • (1996) J. Neurochem. , vol.67 , pp. 1761-1765
    • Sastre, M.1    Regunathan, S.2    Galea, E.3    Reis, D.J.4
  • 256
    • 4644298831 scopus 로고    scopus 로고
    • Polyamines increase in sympathetic neurons and non-neuronal cells after axotomy and enhance neurite outgrowth in nerve growth factor-primed PC12 cells
    • [256] Schreiber, R.C., Boeshore, K.L., Laube, G., Veh, R.W., Zigmond, R.E., Polyamines increase in sympathetic neurons and non-neuronal cells after axotomy and enhance neurite outgrowth in nerve growth factor-primed PC12 cells. Neuroscience 128 (2004), 741–749.
    • (2004) Neuroscience , vol.128 , pp. 741-749
    • Schreiber, R.C.1    Boeshore, K.L.2    Laube, G.3    Veh, R.W.4    Zigmond, R.E.5
  • 257
    • 0038721692 scopus 로고    scopus 로고
    • Regulation of ion channel/neurotransmitter receptor function by RNA editing
    • [257] Seeburg, P.H., Hartner, J., Regulation of ion channel/neurotransmitter receptor function by RNA editing. Curr. Opin. Neurobiol. 13 (2003), 279–283.
    • (2003) Curr. Opin. Neurobiol. , vol.13 , pp. 279-283
    • Seeburg, P.H.1    Hartner, J.2
  • 258
    • 0033957414 scopus 로고    scopus 로고
    • Spermine-induced toxicity in cerebellar granule neurons is independent of its actions at NMDA receptors
    • [258] Segal, J.A., Skolnick, P., Spermine-induced toxicity in cerebellar granule neurons is independent of its actions at NMDA receptors. J. Neurochem. 74 (2000), 60–69.
    • (2000) J. Neurochem. , vol.74 , pp. 60-69
    • Segal, J.A.1    Skolnick, P.2
  • 259
    • 0019831608 scopus 로고
    • Polyamine metabolism and function in brain
    • [259] Seiler, N., Polyamine metabolism and function in brain. Neurochem. Int. 3 (1981), 95–110.
    • (1981) Neurochem. Int. , vol.3 , pp. 95-110
    • Seiler, N.1
  • 260
    • 0020601156 scopus 로고
    • Brain polyamines and aggressive behavior of isolated mice
    • [260] Seiler, N., Brain polyamines and aggressive behavior of isolated mice. Neurochem. Int. 5 (1983), 363–364.
    • (1983) Neurochem. Int. , vol.5 , pp. 363-364
    • Seiler, N.1
  • 261
    • 0001800029 scopus 로고
    • Formation, catabolism and properties of natural polyamines
    • Carter C Academic Press London
    • [261] Seiler, N., Formation, catabolism and properties of natural polyamines. Carter C, (eds.) Neuropharmacology of Polyamines, 1994, Academic Press, London, 1–36.
    • (1994) Neuropharmacology of Polyamines , pp. 1-36
    • Seiler, N.1
  • 262
    • 3042653176 scopus 로고    scopus 로고
    • Catabolism of polyamines
    • [262] Seiler, N., Catabolism of polyamines. Amino Acids 26 (2004), 217–233.
    • (2004) Amino Acids , vol.26 , pp. 217-233
    • Seiler, N.1
  • 263
    • 0016614399 scopus 로고
    • Regional distribution of putrescine, spermidine and spermine in relation to the distribution of RNA and DNA in the rat nervous system
    • [263] Seiler, N., Schmidt-Glenewinkel, T., Regional distribution of putrescine, spermidine and spermine in relation to the distribution of RNA and DNA in the rat nervous system. J. Neurochem. 24 (1975), 791–795.
    • (1975) J. Neurochem. , vol.24 , pp. 791-795
    • Seiler, N.1    Schmidt-Glenewinkel, T.2
  • 264
    • 0018291386 scopus 로고
    • On the formation of gamma-aminobutyric acid from putrescine in brain
    • [264] Seiler, N., Schmidt-Glenewinkel, T., Sarhan, S., On the formation of gamma-aminobutyric acid from putrescine in brain. J. Biochem. 86 (1979), 277–278.
    • (1979) J. Biochem. , vol.86 , pp. 277-278
    • Seiler, N.1    Schmidt-Glenewinkel, T.2    Sarhan, S.3
  • 266
    • 0018320658 scopus 로고
    • The polyamines in the central nervous system
    • [266] Shaw, G.G., The polyamines in the central nervous system. Biochem. Pharmacol. 28 (1979), 1–6.
    • (1979) Biochem. Pharmacol. , vol.28 , pp. 1-6
    • Shaw, G.G.1
  • 267
    • 0018305927 scopus 로고
    • The synthesis and turnover of spermidine and spermine in mouse brain
    • [267] Shaw, G.G., The synthesis and turnover of spermidine and spermine in mouse brain. Neurochem. Res. 4 (1979), 269–275.
    • (1979) Neurochem. Res. , vol.4 , pp. 269-275
    • Shaw, G.G.1
  • 268
    • 0034990845 scopus 로고    scopus 로고
    • Lipopolysaccharide causes deficits in spatial learning in the watermaze but not in BDNF expression in the rat dentate gyrus
    • [268] Shaw, K.N., Commins, S., O'Mara, S.M., Lipopolysaccharide causes deficits in spatial learning in the watermaze but not in BDNF expression in the rat dentate gyrus. Behav. Brain Res. 124 (2001), 47–54.
    • (2001) Behav. Brain Res. , vol.124 , pp. 47-54
    • Shaw, K.N.1    Commins, S.2    O'Mara, S.M.3
  • 269
    • 0027963199 scopus 로고
    • Spermidine potentiates dizocilpine-induced impairment of learning performance by rats in a 14-unit T-maze
    • [269] Shimada, A., Spangler, E.L., London, E.D., Ingram, D.K., Spermidine potentiates dizocilpine-induced impairment of learning performance by rats in a 14-unit T-maze. Eur. J. Pharmacol. 263 (1994), 293–300.
    • (1994) Eur. J. Pharmacol. , vol.263 , pp. 293-300
    • Shimada, A.1    Spangler, E.L.2    London, E.D.3    Ingram, D.K.4
  • 270
    • 0021964550 scopus 로고
    • Limited blood-brain barrier transport of polyamines
    • [270] Shin, W.W., Fong, W.F., Pang, S.F., Wong, P.C., Limited blood-brain barrier transport of polyamines. J. Neurochem. 44 (1985), 1056–1059.
    • (1985) J. Neurochem. , vol.44 , pp. 1056-1059
    • Shin, W.W.1    Fong, W.F.2    Pang, S.F.3    Wong, P.C.4
  • 271
    • 0036353345 scopus 로고    scopus 로고
    • The role of PKA, CaMKII, and PKC in avoidance conditioning: permissive or instructive?
    • [271] Shobe, J., The role of PKA, CaMKII, and PKC in avoidance conditioning: permissive or instructive?. Neurobiol. Learn. Mem. 77 (2002), 219–312.
    • (2002) Neurobiol. Learn. Mem. , vol.77 , pp. 219-312
    • Shobe, J.1
  • 274
    • 84930588471 scopus 로고    scopus 로고
    • Intracellular spermine prevents acid-induced uncoupling of Cx43 gap junction channels
    • [274] Skatchkov, S.N., Bukauskas, F.F., Benedikt, J., Inyushin, M., Kucheryavykh, Y.V., Intracellular spermine prevents acid-induced uncoupling of Cx43 gap junction channels. Neuroreport 26 (2015), 528–532.
    • (2015) Neuroreport , vol.26 , pp. 528-532
    • Skatchkov, S.N.1    Bukauskas, F.F.2    Benedikt, J.3    Inyushin, M.4    Kucheryavykh, Y.V.5
  • 276
    • 0022899164 scopus 로고
    • Role of ornithine decarboxylase and the polyamines in nervous system development: a review
    • [276] Slotkin, T.A., Bartolome, J., Role of ornithine decarboxylase and the polyamines in nervous system development: a review. Brain Res. Bull. 17 (1986), 307–320.
    • (1986) Brain Res. Bull. , vol.17 , pp. 307-320
    • Slotkin, T.A.1    Bartolome, J.2
  • 277
    • 0021067791 scopus 로고
    • Role of ornithine decarboxylase and the polyamines in nervous system development: Short-term postnatal administration of alpha-difluoromethylornithine, an irreversible inhibitor of ornithine decarboxylase
    • [277] Slotkin, T.A., Whitmore, W.L., Lerea, L., Slepetis, R.J., Weigel, S.J., Trepanier, P.A., Seidler, F.J., Role of ornithine decarboxylase and the polyamines in nervous system development: Short-term postnatal administration of alpha-difluoromethylornithine, an irreversible inhibitor of ornithine decarboxylase. Int. J. Dev. Neurosci. 1 (1983), 7–16.
    • (1983) Int. J. Dev. Neurosci. , vol.1 , pp. 7-16
    • Slotkin, T.A.1    Whitmore, W.L.2    Lerea, L.3    Slepetis, R.J.4    Weigel, S.J.5    Trepanier, P.A.6    Seidler, F.J.7
  • 278
    • 0018782823 scopus 로고
    • Physostigmine in alzheimer's disease
    • [278] Smith, C., Swash, M., Physostigmine in alzheimer's disease. Lancet, 313, 1979, 42.
    • (1979) Lancet , vol.313 , pp. 42
    • Smith, C.1    Swash, M.2
  • 279
    • 19944391381 scopus 로고    scopus 로고
    • The olfactory bulbectomised rat as a model of depression
    • [279] Song, C., Leonard, B.E., The olfactory bulbectomised rat as a model of depression. Neurosci. Biobehav. Rev. 29 (2005), 627–647.
    • (2005) Neurosci. Biobehav. Rev. , vol.29 , pp. 627-647
    • Song, C.1    Leonard, B.E.2
  • 280
    • 84906535671 scopus 로고    scopus 로고
    • Molecular mechanisms contributing to TARP regulation of channel conductance and polyamine block of calcium-permeable AMPA receptors
    • [280] Soto, D., Coombs, I.D., Gratacos-Batlle, E., Farrant, M., Cull-Candy, S.G., Molecular mechanisms contributing to TARP regulation of channel conductance and polyamine block of calcium-permeable AMPA receptors. J. Neurosci. 34 (2014), 11673–11683.
    • (2014) J. Neurosci. , vol.34 , pp. 11673-11683
    • Soto, D.1    Coombs, I.D.2    Gratacos-Batlle, E.3    Farrant, M.4    Cull-Candy, S.G.5
  • 281
    • 0031262221 scopus 로고    scopus 로고
    • Neurotoxicity of polyamines and pharmacological neuroprotection in cultures of rat cerebellar granule cells
    • [281] Sparapani, M., Dall'Olio, R., Gandolfi, O., Ciani, E., Contestabile, A., Neurotoxicity of polyamines and pharmacological neuroprotection in cultures of rat cerebellar granule cells. Exp. Neurol. 148 (1997), 157–166.
    • (1997) Exp. Neurol. , vol.148 , pp. 157-166
    • Sparapani, M.1    Dall'Olio, R.2    Gandolfi, O.3    Ciani, E.4    Contestabile, A.5
  • 282
    • 79951857448 scopus 로고    scopus 로고
    • Protein kinase CK2 links polyamine metabolism to MAPK signalling in Drosophila
    • [282] Stark, F., Pfannstiel, J., Klaiber, I., Raabe, T., Protein kinase CK2 links polyamine metabolism to MAPK signalling in Drosophila. Cell. Signal. 23 (2011), 876–882.
    • (2011) Cell. Signal. , vol.23 , pp. 876-882
    • Stark, F.1    Pfannstiel, J.2    Klaiber, I.3    Raabe, T.4
  • 283
    • 0030200688 scopus 로고    scopus 로고
    • Quantitation of the putative neurotransmitter agmatine as the hexafluoroacetylacetonate derivative by stable isotope dilution gas chromatography and negative-ion chemical ionization mass spectrometry
    • [283] Stickle, D., Bohrer, A., Berger, R., Morrissey, J., Klahr, S., Turk, J., Quantitation of the putative neurotransmitter agmatine as the hexafluoroacetylacetonate derivative by stable isotope dilution gas chromatography and negative-ion chemical ionization mass spectrometry. Anal. Biochem. 238 (1996), 129–136.
    • (1996) Anal. Biochem. , vol.238 , pp. 129-136
    • Stickle, D.1    Bohrer, A.2    Berger, R.3    Morrissey, J.4    Klahr, S.5    Turk, J.6
  • 284
    • 0026766877 scopus 로고
    • Structures and properties of seven isoforms of the NMDA receptor generated by alternative splicing
    • [284] Sugihara, H., Moriyoshi, K., Ishii, T., Masu, M., Nakanishi, S., Structures and properties of seven isoforms of the NMDA receptor generated by alternative splicing. Biochem. Biophys. Res. Commun. 185 (1992), 826–832.
    • (1992) Biochem. Biophys. Res. Commun. , vol.185 , pp. 826-832
    • Sugihara, H.1    Moriyoshi, K.2    Ishii, T.3    Masu, M.4    Nakanishi, S.5
  • 285
    • 0030799381 scopus 로고    scopus 로고
    • Modulation of a cAMP protein kinase A cascade by protein kinase C in sensory neurons of Aplysia
    • [285] Sugita, S., Baxter, D.A., Byrne, J.H., Modulation of a cAMP protein kinase A cascade by protein kinase C in sensory neurons of Aplysia. J. Neurosci. 17 (1997), 7237–7244.
    • (1997) J. Neurosci. , vol.17 , pp. 7237-7244
    • Sugita, S.1    Baxter, D.A.2    Byrne, J.H.3
  • 286
    • 0028034803 scopus 로고
    • Identification of two cysteine residues that are required for redox modulation of the NMDA subtype of glutamate receptor
    • [286] Sullivan, J.M., Traynelis, S.F., Chen, H.S., Escobar, W., Heinemann, S.F., Lipton, S.A., Identification of two cysteine residues that are required for redox modulation of the NMDA subtype of glutamate receptor. Neuron 13 (1994), 929–936.
    • (1994) Neuron , vol.13 , pp. 929-936
    • Sullivan, J.M.1    Traynelis, S.F.2    Chen, H.S.3    Escobar, W.4    Heinemann, S.F.5    Lipton, S.A.6
  • 288
    • 0016269564 scopus 로고
    • Behavioral pharmacological study of alkali-metals. 3. Changes in brain polyamines and emotional behavior in mice when aggressive mice induced by isolation were moved to grouped circumstances
    • [288] Tadano, T., Behavioral pharmacological study of alkali-metals. 3. Changes in brain polyamines and emotional behavior in mice when aggressive mice induced by isolation were moved to grouped circumstances. Folia Pharmacol. Jpn. 70 (1974), 457–464.
    • (1974) Folia Pharmacol. Jpn. , vol.70 , pp. 457-464
    • Tadano, T.1
  • 289
    • 0016243212 scopus 로고
    • Behavioral pharmacological study of alkali-metal 2. Changes of brain polyamine in aggressive mice induced by electro-shock and isolation, and effects of LiCl on behavior in aggressive mice
    • [289] Tadano, T., Onoki, M., Kisara, K., Behavioral pharmacological study of alkali-metal 2. Changes of brain polyamine in aggressive mice induced by electro-shock and isolation, and effects of LiCl on behavior in aggressive mice. Folia Pharmacol. Jpn. 70 (1974), 9–18.
    • (1974) Folia Pharmacol. Jpn. , vol.70 , pp. 9-18
    • Tadano, T.1    Onoki, M.2    Kisara, K.3
  • 291
    • 0030564998 scopus 로고    scopus 로고
    • Administration of amyloid beta-peptides in the rat medial septum causes memory deficits: reversal by SR 57746A, a non-peptide neurotrophic compound
    • [291] Terranova, J.P., Kan, J.P., Storme, J.J., Perreaut, P., Le Fur, G., Soubrie, P., Administration of amyloid beta-peptides in the rat medial septum causes memory deficits: reversal by SR 57746A, a non-peptide neurotrophic compound. Neurosci. Lett. 213 (1996), 79–82.
    • (1996) Neurosci. Lett. , vol.213 , pp. 79-82
    • Terranova, J.P.1    Kan, J.P.2    Storme, J.J.3    Perreaut, P.4    Le Fur, G.5    Soubrie, P.6
  • 292
    • 84943357229 scopus 로고    scopus 로고
    • Nicotinic ligands as multifunctional agents for the treatment of neuropsychiatric disorders
    • [292] Terry, A.V., Callahan, P.M., Hernandez, C.M., Nicotinic ligands as multifunctional agents for the treatment of neuropsychiatric disorders. Biochem. Pharmacol. 97 (2015), 388–398.
    • (2015) Biochem. Pharmacol. , vol.97 , pp. 388-398
    • Terry, A.V.1    Callahan, P.M.2    Hernandez, C.M.3
  • 294
    • 0035099627 scopus 로고    scopus 로고
    • Polyamines in cell growth and cell death: molecular mechanisms and therapeutic applications
    • [294] Thomas, T., Thomas, T.J., Polyamines in cell growth and cell death: molecular mechanisms and therapeutic applications. Cell. Mol. Life Sci. 58 (2001), 244–258.
    • (2001) Cell. Mol. Life Sci. , vol.58 , pp. 244-258
    • Thomas, T.1    Thomas, T.J.2
  • 295
    • 0001697691 scopus 로고
    • Social memory of the male laboratory rat
    • [295] Thor, D.H., Holloway, W.R., Social memory of the male laboratory rat. J. Comp. Physiol. Psychol. 96 (1982), 1000–1006.
    • (1982) J. Comp. Physiol. Psychol. , vol.96 , pp. 1000-1006
    • Thor, D.H.1    Holloway, W.R.2
  • 296
    • 84859712314 scopus 로고    scopus 로고
    • Hippocampal polyamine levels and transglutaminase activity are paralleling spatial memory retrieval in the C57BL/6J mouse
    • [296] Tiboldi, A., Lentini, A., Provenzano, B., Tabolacci, C., Hoger, H., Beninati, S., Lubec, G., Hippocampal polyamine levels and transglutaminase activity are paralleling spatial memory retrieval in the C57BL/6J mouse. Hippocampus 22 (2012), 1068–1074.
    • (2012) Hippocampus , vol.22 , pp. 1068-1074
    • Tiboldi, A.1    Lentini, A.2    Provenzano, B.3    Tabolacci, C.4    Hoger, H.5    Beninati, S.6    Lubec, G.7
  • 297
    • 84938082730 scopus 로고    scopus 로고
    • Using the spatial learning index to evaluate performance on the water maze
    • [297] Tomas Pereira, I., Burwell, R.D., Using the spatial learning index to evaluate performance on the water maze. Behav. Neurosci. 129 (2015), 533–539.
    • (2015) Behav. Neurosci. , vol.129 , pp. 533-539
    • Tomas Pereira, I.1    Burwell, R.D.2
  • 298
    • 84954321696 scopus 로고    scopus 로고
    • A nonrewarding nmdar antagonist impairs the acquisition, consolidation and expression of morphine conditioned place preference in mice
    • [298] Tomazi, L., Mello, C.F., Schöffer, A.P., Girardi, B.A., Fruhauf, P.K., Rubin, M.A., A nonrewarding nmdar antagonist impairs the acquisition, consolidation and expression of morphine conditioned place preference in mice. Mol. Neurobiol., 2016 http://dx.doi.org/10.1007/s12035-015-9678-0.
    • (2016) Mol. Neurobiol.
    • Tomazi, L.1    Mello, C.F.2    Schöffer, A.P.3    Girardi, B.A.4    Fruhauf, P.K.5    Rubin, M.A.6
  • 299
    • 0023757051 scopus 로고
    • Intra-ventricular infusion of the NMDA antagonist AP5 impairs performance on a non-spatial operant DRL task in the rat
    • [299] Tonkiss, J., Morris, R.G., Rawlins, J.N., Intra-ventricular infusion of the NMDA antagonist AP5 impairs performance on a non-spatial operant DRL task in the rat. Exp. Brain Res. 73 (1988), 181–188.
    • (1988) Exp. Brain Res. , vol.73 , pp. 181-188
    • Tonkiss, J.1    Morris, R.G.2    Rawlins, J.N.3
  • 300
    • 0029021010 scopus 로고
    • Control of proton sensitivity of the NMDA receptor by RNA splicing and polyamines
    • [300] Traynelis, S.F., Hartley, M., Heinemann, S.F., Control of proton sensitivity of the NMDA receptor by RNA splicing and polyamines. Science 268 (1995), 873–876.
    • (1995) Science , vol.268 , pp. 873-876
    • Traynelis, S.F.1    Hartley, M.2    Heinemann, S.F.3
  • 301
    • 0032436807 scopus 로고    scopus 로고
    • Measuring reward with the conditioned place preference paradigm: a comprehensive review of drug effects, recent progress and new issues
    • [301] Tzschentke, T.M., Measuring reward with the conditioned place preference paradigm: a comprehensive review of drug effects, recent progress and new issues. Prog. Neurobiol. 56 (1998), 613–672.
    • (1998) Prog. Neurobiol. , vol.56 , pp. 613-672
    • Tzschentke, T.M.1
  • 302
    • 34547610708 scopus 로고    scopus 로고
    • Measuring reward with the conditioned place preference (CPP) paradigm: update of the last decade
    • [302] Tzschentke, T.M., Measuring reward with the conditioned place preference (CPP) paradigm: update of the last decade. Addict. Biol. 12 (2007), 227–462.
    • (2007) Addict. Biol. , vol.12 , pp. 227-462
    • Tzschentke, T.M.1
  • 304
    • 84870405482 scopus 로고    scopus 로고
    • A new target for diagnosis and treatment of CNS disorders: agmatinergic system
    • [304] Uzbay, T., A new target for diagnosis and treatment of CNS disorders: agmatinergic system. Curr. Med. Chem. 19 (2012), 5116–5121.
    • (2012) Curr. Med. Chem. , vol.19 , pp. 5116-5121
    • Uzbay, T.1
  • 305
    • 82855165088 scopus 로고    scopus 로고
    • The pharmacological importance of agmatine in the brain
    • [305] Uzbay, T.I., The pharmacological importance of agmatine in the brain. Neurosci. Biobehav. Rev. 36 (2012), 502–519.
    • (2012) Neurosci. Biobehav. Rev. , vol.36 , pp. 502-519
    • Uzbay, T.I.1
  • 308
    • 33846461062 scopus 로고    scopus 로고
    • Morris water maze: procedures for assessing spatial and related forms of learning and memory
    • [308] Vorhees, C.V., Williams, M.T., Morris water maze: procedures for assessing spatial and related forms of learning and memory. Nat. Protoc. 1 (2006), 848–858.
    • (2006) Nat. Protoc. , vol.1 , pp. 848-858
    • Vorhees, C.V.1    Williams, M.T.2
  • 309
    • 4143049044 scopus 로고    scopus 로고
    • Inhibitors of polyamine metabolism: review article
    • [309] Wallace, H.M., Fraser, A.V., Inhibitors of polyamine metabolism: review article. Amino Acids 26 (2004), 353–365.
    • (2004) Amino Acids , vol.26 , pp. 353-365
    • Wallace, H.M.1    Fraser, A.V.2
  • 310
    • 0345688128 scopus 로고    scopus 로고
    • A perspective of polyamine metabolism
    • [310] Wallace, H.M., Fraser, A.V., Hughes, A., A perspective of polyamine metabolism. Biochem. J. 376 (2003), 1–14.
    • (2003) Biochem. J. , vol.376 , pp. 1-14
    • Wallace, H.M.1    Fraser, A.V.2    Hughes, A.3
  • 311
    • 0033013759 scopus 로고    scopus 로고
    • Radioprotection of human cell nuclear DNA by polyamines: radiosensitivity of chromatin is influenced by tightly bound spermine
    • [311] Warters, R.L., Newton, G.L., Olive, P.L., Fahey, R.C., Radioprotection of human cell nuclear DNA by polyamines: radiosensitivity of chromatin is influenced by tightly bound spermine. Radiat. Res. 151 (1999), 354–362.
    • (1999) Radiat. Res. , vol.151 , pp. 354-362
    • Warters, R.L.1    Newton, G.L.2    Olive, P.L.3    Fahey, R.C.4
  • 312
    • 0017408247 scopus 로고
    • Effects of spermine and spermidine on single brain stem neurones
    • [312] Wedgwood, M.A., Wolstencroft, J.H., Effects of spermine and spermidine on single brain stem neurones. Neuropharmacology 16 (1977), 445–446.
    • (1977) Neuropharmacology , vol.16 , pp. 445-446
    • Wedgwood, M.A.1    Wolstencroft, J.H.2
  • 313
    • 0028069856 scopus 로고
    • Mechanisms influencing stimulatory effects of spermine at recombinant N-methyl-D-aspartate receptors
    • [313] Williams, K., Mechanisms influencing stimulatory effects of spermine at recombinant N-methyl-D-aspartate receptors. Mol. Pharmacol. 46 (1994), 161–168.
    • (1994) Mol. Pharmacol. , vol.46 , pp. 161-168
    • Williams, K.1
  • 314
    • 0028821024 scopus 로고
    • Pharmacological properties of recombinant N-methyl-D-aspartate (NMDA) receptors containing the epsilon 4 (NR2D) subunit
    • [314] Williams, K., Pharmacological properties of recombinant N-methyl-D-aspartate (NMDA) receptors containing the epsilon 4 (NR2D) subunit. Neurosci. Lett. 184 (1995), 181–184.
    • (1995) Neurosci. Lett. , vol.184 , pp. 181-184
    • Williams, K.1
  • 315
    • 0030853492 scopus 로고    scopus 로고
    • Interactions of polyamines with ion channels
    • [315] Williams, K., Interactions of polyamines with ion channels. Biochem. J. 325 (1997), 289–297.
    • (1997) Biochem. J. , vol.325 , pp. 289-297
    • Williams, K.1
  • 316
    • 84886698762 scopus 로고    scopus 로고
    • Frontiers in neuroscience. extracellular modulation of NMDA receptors
    • A.M. Van Dongen CRC Press, Taylor & Francis Group, LLC Boca Raton (FL)
    • [316] Williams, K., Frontiers in neuroscience. extracellular modulation of NMDA receptors. Van Dongen, A.M., (eds.) Biology of the NMDA Receptor, 2009, CRC Press, Taylor & Francis Group, LLC, Boca Raton (FL).
    • (2009) Biology of the NMDA Receptor
    • Williams, K.1
  • 317
    • 0024448447 scopus 로고
    • Effects of polyamines on the binding of [3H]MK-801 to the N-methyl-D-aspartate receptor: pharmacological evidence for the existence of a polyamine recognition site
    • [317] Williams, K., Romano, C., Molinoff, P.B., Effects of polyamines on the binding of [3H]MK-801 to the N-methyl-D-aspartate receptor: pharmacological evidence for the existence of a polyamine recognition site. Mol. Pharmacol. 36 (1989), 575–581.
    • (1989) Mol. Pharmacol. , vol.36 , pp. 575-581
    • Williams, K.1    Romano, C.2    Molinoff, P.B.3
  • 318
    • 0025063670 scopus 로고
    • Characterization of polyamines having agonist, antagonist, and inverse agonist effects at the polyamine recognition site of the NMDA receptor
    • [318] Williams, K., Dawson, V.L., Romano, C., Dichter, M.A., Molinoff, P.B., Characterization of polyamines having agonist, antagonist, and inverse agonist effects at the polyamine recognition site of the NMDA receptor. Neuron 5 (1990), 199–208.
    • (1990) Neuron , vol.5 , pp. 199-208
    • Williams, K.1    Dawson, V.L.2    Romano, C.3    Dichter, M.A.4    Molinoff, P.B.5
  • 319
    • 0028340993 scopus 로고
    • Sensitivity of the N-methyl-D-aspartate receptor to polyamines is controlled by Nr2 subunits
    • [319] Williams, K., Zappia, A.M., Pritchett, D.B., Shen, Y.M., Molinoff, P.B., Sensitivity of the N-methyl-D-aspartate receptor to polyamines is controlled by Nr2 subunits. Mol. Pharmacol. 45 (1994), 803–809.
    • (1994) Mol. Pharmacol. , vol.45 , pp. 803-809
    • Williams, K.1    Zappia, A.M.2    Pritchett, D.B.3    Shen, Y.M.4    Molinoff, P.B.5
  • 320
    • 33947689120 scopus 로고    scopus 로고
    • The concept of aldehyde load in neurodegenerative mechanisms: cytotoxicity of the polyamine degradation products hydrogen peroxide, acrolein, 3-aminopropanal, 3-acetamidopropanal and 4-aminobutanal in a retinal ganglion cell line
    • [320] Wood, P.L., Khan, M.A., Moskal, J.R., The concept of aldehyde load in neurodegenerative mechanisms: cytotoxicity of the polyamine degradation products hydrogen peroxide, acrolein, 3-aminopropanal, 3-acetamidopropanal and 4-aminobutanal in a retinal ganglion cell line. Brain Res. 1145 (2007), 150–156.
    • (2007) Brain Res. , vol.1145 , pp. 150-156
    • Wood, P.L.1    Khan, M.A.2    Moskal, J.R.3
  • 323
    • 84863232569 scopus 로고    scopus 로고
    • Oligoamine analogues in combination with 2-difluoromethylornithine synergistically induce re-expression of aberrantly silenced tumour-suppressor genes
    • [323] Wu, Y., Steinbergs, N., Murray-Stewart, T., Marton, L.J., Casero, R.A., Oligoamine analogues in combination with 2-difluoromethylornithine synergistically induce re-expression of aberrantly silenced tumour-suppressor genes. Biochem. J. 442 (2012), 693–701.
    • (2012) Biochem. J. , vol.442 , pp. 693-701
    • Wu, Y.1    Steinbergs, N.2    Murray-Stewart, T.3    Marton, L.J.4    Casero, R.A.5
  • 324
    • 41149122203 scopus 로고    scopus 로고
    • Dopamine and ethanol cause translocation of epsilon PKC associated with epsilon RACK: cross-talk between cAMP-dependent protein kinase A and protein kinase C signaling pathways
    • [324] Yao, L., Fan, P.D., Jiang, Z., Gordon, A., Mochly-Rosen, D., Diamond, I., Dopamine and ethanol cause translocation of epsilon PKC associated with epsilon RACK: cross-talk between cAMP-dependent protein kinase A and protein kinase C signaling pathways. Mol. Pharmacol. 73 (2008), 1105–1112.
    • (2008) Mol. Pharmacol. , vol.73 , pp. 1105-1112
    • Yao, L.1    Fan, P.D.2    Jiang, Z.3    Gordon, A.4    Mochly-Rosen, D.5    Diamond, I.6
  • 325
    • 0033583252 scopus 로고    scopus 로고
    • Alzheimer's amyloid beta-peptide associated free radicals increase rat embryonic neuronal polyamine uptake and ornithine decarboxylase activity: protective effect of vitamin E
    • [325] Yatin, S.M., Yatin, M., Aulick, T., Ain, K.B., Butterfield, D.A., Alzheimer's amyloid beta-peptide associated free radicals increase rat embryonic neuronal polyamine uptake and ornithine decarboxylase activity: protective effect of vitamin E. Neurosci. Lett. 263 (1999), 17–20.
    • (1999) Neurosci. Lett. , vol.263 , pp. 17-20
    • Yatin, S.M.1    Yatin, M.2    Aulick, T.3    Ain, K.B.4    Butterfield, D.A.5
  • 326
    • 0035282733 scopus 로고    scopus 로고
    • Role of spermine in amyloid beta-peptide-associated free radical-induced neurotoxicity
    • [326] Yatin, S.M., Yatin, M., Varadarajan, S., Ain, K.B., Butterfield, D.A., Role of spermine in amyloid beta-peptide-associated free radical-induced neurotoxicity. J. Neurosci. Res. 63 (2001), 395–401.
    • (2001) J. Neurosci. Res. , vol.63 , pp. 395-401
    • Yatin, S.M.1    Yatin, M.2    Varadarajan, S.3    Ain, K.B.4    Butterfield, D.A.5
  • 329
    • 34250012302 scopus 로고    scopus 로고
    • Nitric oxide modulates state dependency induced by lithium in an inhibitory avoidance task in mice
    • [329] Zarrindast, M.R., Shendy, M.M., Ahmadi, S., Nitric oxide modulates state dependency induced by lithium in an inhibitory avoidance task in mice. Behav. Pharmacol. 18 (2007), 289–295.
    • (2007) Behav. Pharmacol. , vol.18 , pp. 289-295
    • Zarrindast, M.R.1    Shendy, M.M.2    Ahmadi, S.3
  • 331
    • 0032997381 scopus 로고    scopus 로고
    • Mutation of structural determinants lining the N-methyl-D-aspartate receptor channel differentially affects phencyclidine block and spermine potentiation and block
    • [331] Zheng, X., Zhang, L., Wang, A.P., Araneda, R.C., Lin, Y., Zukin, R.S., Bennett, M.V., Mutation of structural determinants lining the N-methyl-D-aspartate receptor channel differentially affects phencyclidine block and spermine potentiation and block. Neuroscience 93 (1999), 125–134.
    • (1999) Neuroscience , vol.93 , pp. 125-134
    • Zheng, X.1    Zhang, L.2    Wang, A.P.3    Araneda, R.C.4    Lin, Y.5    Zukin, R.S.6    Bennett, M.V.7
  • 332
    • 77951803048 scopus 로고    scopus 로고
    • NMDA receptor antagonism in the basolateral but not central amygdala blocks the extinction of Pavlovian fear conditioning in rats
    • [332] Zimmerman, J.M., Maren, S., NMDA receptor antagonism in the basolateral but not central amygdala blocks the extinction of Pavlovian fear conditioning in rats. Eur. J. Neurosci. 31 (2010), 1664–1670.
    • (2010) Eur. J. Neurosci. , vol.31 , pp. 1664-1670
    • Zimmerman, J.M.1    Maren, S.2
  • 333
    • 33750352828 scopus 로고    scopus 로고
    • Putrescine produces antidepressant-like effects in the forced swimming test and in the tail suspension test in mice
    • [333] Zomkowski, A.D., Santos, A.R., Rodrigues, A.L., Putrescine produces antidepressant-like effects in the forced swimming test and in the tail suspension test in mice. Prog. Neuropsychopharmacol. Biol. Psychiatry. 30 (2006), 1419–1425.
    • (2006) Prog. Neuropsychopharmacol. Biol. Psychiatry. , vol.30 , pp. 1419-1425
    • Zomkowski, A.D.1    Santos, A.R.2    Rodrigues, A.L.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.