Effect of multiple ifenprodil or spermidine treatment on social recognition in rats

Journal of Basic and Clinical Physiology and Pharmacology

Volumn 13, Issue 1, 2002, Pages 61-68

  Mikolajczak, Przemyslaw ^a   Okulicz Kozaryn, Irena ^a   Polanska, Anna ^a   Szczawinska, Krystyna ^a   Bobkiewicz Kozlowska, Teresa ^a  

^a POZNAN UNIVERSITY OF MEDICAL SCIENCES   (Poland)

Author keywords

polyamines; short term memory; social memory test; subchronic administration

Indexed keywords

IFENPRODIL; POLYAMINE; SPERMIDINE;

AMNESIA; ANIMAL BEHAVIOR; ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; DOSE TIME EFFECT RELATION; DRUG EFFECT; DRUG MECHANISM; MALE; MEMORY CONSOLIDATION; NEUROTOXICITY; NONHUMAN; RECOGNITION; SHORT TERM MEMORY;

ADRENERGIC ALPHA-ANTAGONISTS; ANIMALS; BEHAVIOR, ANIMAL; INJECTIONS, INTRAPERITONEAL; MALE; MEMORY, SHORT-TERM; PIPERIDINES; RATS; RATS, WISTAR; RECOGNITION (PSYCHOLOGY); SPERMIDINE;

EID: 0036402516     PISSN: 07926855     EISSN: 21910286     Source Type: Journal    
DOI: 10.1515/JBCPP.2002.13.1.61     Document Type: Article

References (12)

1. Yamakura, T, Shimoji, K. Subunit- and site-specific pharmacology of the NMDA receptor channel. Prog Neurobiol 1999; 59: 279–298. Review.
2. Meyer, RC, Knox, J, Purwin, DA, Spangler, EL, Ingram, DK. Combined stimulation of the glycine and polyamine sites of the NMDA receptor attenuates NMDA blockade-induced learning deficits of rats in a 14-unit T-maze. Psychopharmacology (Berl). 1998; 135: 290–295.
3. Shimada, A, Spangler, EL, London, ED, Ingram, DK. Spermidine potentiates dizocilpine-induced impairment of learning performance by rats in a 14-unit T-maze. Eur J Pharmacol 1994; 263: 293–300.
4. Rubin, MA, Stiegemeier, JA, Volkweis, MA, Oliveira, DM, Fenili, AC, Boemo, RL, et al. Intra-amygdala spermidine administration improves inhibitory avoidance performance in rats. Eur J Pharmacol 2001; 423, 35–39.
5. Williams, K, Zappia, AM, Prichett, DB, Shen, YM., Molinoff, PB. Sensitivity of the N-methyl-D-aspartate receptor to polyamines is controlled by NR2 subunits. Mol Pharmacol 1994; 45: 803–809.
6. Doyle, KM, Feerick, S, Kirkby, DL, Eddleston, A, Higgins, GA. Comparison of various N-methyl-D-aspartate receptor antagonists in a model of short-term memory and on overt behaviour. Behav Pharmacol 1998; 9: 671–681.
7. Murata, S, Kawasaki, K. Common and uncommon behavioural effects of antagonists for different modulatory sites in the NMDA receptor/channel complex. Eur J Pharmacol 1993; 239: 9–15.
8. Seidl, R, Beninati, S, Cairns, N, Singewald, N, Risser, D, Bavan, H, et al. Polyamines in frontal cortex of patients with Down syndrome and Alzheimer disease. Neurosci Lett 1996; 206: 193–195.
9. O&Mahony, S, Harkany, T, Rensink, AA, Abraham, I, De Jong, GI, Varga, JL, et al. Beta-amyloid-induced cholinergic denervation correlates with enhanced nitric oxide synthase activity in rat cerebral cortex: reversal by NMDA receptor blockade. Brain Res Bull 1998; 45: 405–411.
10. Popik, P, van Ree, JM. Neurohypophyseal peptides and social recognition in rats. Prog Brain Res 1998; 119: 415–436. Review.
11. London, ED, Mukhin, A. Polyamines as endogenous modulators of the N-methyl-D-aspartate receptor. Ann NY Acad Sci 1995; 757: 430–436.
12. Sharma, TA, Reynolds, IJ. Characterization of the effects of polyamines on [125I]MK-801 binding to recombinant N-methyl-D-aspartate receptors. J Pharmacol Exp Ther 1999; 289: 1041–1047.