The neurochemical and behavioral effects of β-amyloid peptide(25-35)

Brain Research

Volumn 720, Issue 1-2, 1996, Pages 54-60

  Chen, Shiouh Yi ^a,b   Wright, John W ^a   Barnes, Charles D ^a  

^a WASHINGTON STATE UNIVERSITY   (United States)

^b UNIVERSITY OF ILLINOIS AT URBANA CHAMPAIGN   (United States)

Author keywords

Locus coeruleus; Norepinephrine; Spatial learning; (25 35)

Indexed keywords

AMYLOID BETA PROTEIN; BRAIN MONOAMINE; DOPAMINE; NORADRENALIN; SEROTONIN;

ALZHEIMER DISEASE; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; HIPPOCAMPUS; HISTOLOGY; LOCUS CERULEUS; MALE; MAZE TEST; NONHUMAN; PRIORITY JOURNAL; RAT; SPATIAL MEMORY;

EID: 0029995815     PISSN: 00068993     EISSN: None     Source Type: Journal    
DOI: 10.1016/0006-8993(96)00136-9     Document Type: Article

References (30)

1. Amaral, D.G. and Witter, M.P., Hippocampus forum: is the hippocampal formation preferentially involved in spatial behavior? Hippocampus, 1 (1991) 221-292.
2. Barnes, C.A., Spatial learning and memory processes: The search for their neurobiological mechanisms in the rat, Trends Neurosci., 11 (1988) 163-169.
3. Chen, S.-Y., Reddy, V.K. and Barnes, C.D., Reduction of tryosine hydroxylase and glutamate in the locus coeruleus as well as choline acetyltransferase in the medial septum following the administration of β(25-35) into the hippocampus, submitted.
4. Chen, S.-Y., Harding, J.W. and Barnes, C.D., Neuropathology of β-amyloid peptide analogues in vivo, Brain Res., in press.
5. Chiodo, L.A., Acheson, A.L., Zigmond, M.J. and Stricker, E.M., Subtotal destruction of central noradrenergic projections increases the firing rate of locus coeruleus cells, Brain Res., 264 (1983) 123-126.
6. Cleary, J., Hittner, J.M., Semotuk, M., Mantyh, P. and O'Hare, E., Beta-amyloid (1-40) effects on behavior and memory, Brain Res., 682 (1995) 69-74.
7. Dahlstrom, A. and Fuxe, K., Evidence for the existence of monoamine-containing neurons in the central nervous system. I. Demonstration of monoamines in the cell bodies of brain stem neurons, Acta Physiol. Scand., 62, Suppl. 232 (1964) 1-55.
8. Dornan, W.A., Kang, D.E., McCampbell, A. and Kang, E.E., Bilateral injections of βA(25-35)+1BO into the hippocampus disrupts acquisition of spatial learning in the rat, Neuroreport, 5 (1993) 165-168.
9. Eichenbaum, H., Stewart, C. and Morris, R.G.M., Hippocampal representation in place learning, J. Neurosci., 10 (1990) 3531-3542.
10. Flood, J.F., Morley, J.E. and Roberts, E., Amnestic effects in mice of four synthetic peptides homologous to amyloid β protein from patients with Alzheimer disease, Proc. Natl. Acad. Sci., 88 (1991) 3363-3366.
11. Flood, J.F., Morley, J.E. and Roberts, E., An amyloid β-protein fragment. Aβ[12-28], equipotently impairs post-training memory processing when injected into different limbic system structures, Brain Res., 663 (1994) 271-276.
12. Harley, C., Noradrenergic and locus coeruleus modulation of the perforant path-evoked potential in rat dentate gyrus supports a role for the locus coeruleus in attentional and memorial processes. In C.D. Barnes and O. Pompeiano (Eds.). Progress in Brain Research, Vol. 88, Elsevier, Amsterdam, 1991, pp. 307-321.
13. Hirsh, R., The hippocampus and contextual retrieval of information from memory. A theory, Behav. Biol. 12 (1974) 421-444.
14. Koh, J., Yang, L.L. and Cotman, C.W., β-amyloid protein increases the vulnerability of cultured cortical neurons to excitotoxic damage, Brain Res., 533 (1990) 315-320.
15. Kowall, N.W., Beal, M.F., Busciglio, J., Duffy, L.K. and Yankner, B.A., An in vivo model for the neurodegenerative effects of beta-amyloid and protection by substance P. Proc. Natl Acad. Sci., 88 (1991) 7247-7251.
16. Kowall, N.W., McKee, A.C., Yankner, B.A. and Beal, M.F., In vivo neurotoxicity of beta amyloid β(1-40) and β(25-35) fragment, Neurobiol. Aging, 13 (1992) 537-542.
17. Mattson, M.P., Cheng, B., Davis, D., Bryant, K., Lieberbung, I. and Rydel, R.E., β-amyloid peptide destabilize calcium homeostasis and render human cortical neurons vulnerable to excitotoxicity, J. Neurosci., 12(2) (1992) 376-389.
18. McDonald, M.P., Dahl, E.E., Overmier, J.B., Mantyh, P. and Cleary, J., Effects of an exogenous β-amyloid peptide on retention for spatial learning, Behav. Neural Biol., 62 (1994) 60-67.
19. McNamara, R.K. and Skelton, R.W., The neuropharmacological and neurochemical basis of place learning in the Morris water maze, Brain Res., 18 (1993) 33-49.
20. Morris, R.G.M., Garrud, P., Rawlins, J.N.P. and O'Keefe, J., Place navigation impaired in rats with hippocampal lesions, Nature, 297 (1982) 681-683.
21. Muller, R.U., Kubie, J.L. and Ranck, J.B. Jr., Spatial firing patterns of hippocampal complex-spike cells in a fixed environment, J. Neurosci., 7 (1987) 1935-1950.
22. O'Keefe, J. and Nadel, L., The Hippocampus as a Cognitive Map. Oxford U.P., Oxford, UK, 1978.
23. Ornstein, K., Milon, H., McRae-Degueurce, A., Alvarez, C., Berger, B. and Wuerzner, H.P., Biochemical and radioautographic evidence for dopaminergic afferents of the locus coeruleus originating in the ventral tegmental area, J. Neural Transm., 70 (1987) 183-191.
24. Sakai, K., Physiological properties and afferent connections of the locus coeruleus and adjacent tegmental neurons involved in the generation of paradoxical sleep in the cat. In C.D. Barnes and O. Pompeiano (Eds.), Progress in Brain Research, Vol. 88, Elsevier, Amsterdam, 1991, pp. 307-321.
25. Swanson, L.W., The projections of the ventral tegmental area and adjacent areas: a combined retrograde tracer and immunofluorescence study in the rat, Brain Res. Bull., 9 (1981) 321-354.
26. Tate, B.A., Rojas, M., Majocha, R.E. and Marotta, C.A., Evaluation of spatial learning in rats receiving β-amyloid infusion, Soc. Neurosci. Abstr., 20 (1994) 1246.
27. Whishaw, I.Q., O'Connor, W.T. and Dunnett, S.B., Disruption of central cholinergic systems in the rat by basal forebrain lesions or atropine: effects on feeding, sensorimotor behavior, locomotor activity and spatial navigation, Behav. Brain Res., 17 (1984) 103-115.
28. Winkler, J., Connor, D.J., Frautschy, S.A., Behl, C., Waitte, J.J., Cole, G.M. and Thai, L.J., Lack of long-term effects after β-amyloid protein injections in rat brain, Neurobiol. Aging, 15 (1994) 601-607.
29. Yamamoto, T. and Hirano, A., Nucleus raphe dorsalis in Alzheimer's disease: Neurofibrillary tangles and loss of large neurons, Ann. Neurol., 17 (1985) 573-577.
30. Yankner, B.A., Duffy, L.K. and Kirschner, D.A., Neurotrophic and neurotoxic effects of amyloid β protein: reversal by tachykinin neuropeptides, Science, 250 (1990) 279-282.