Spermine induces cell death in cultured human embryonic cerebral cortical neurons through N-methyl-D-aspartate receptor activation

Journal of Neuroscience Research

Volumn 86, Issue 4, 2008, Pages 861-872

  De Vera, Nuria ^a   Martínez, Emili ^a   Sanfeliu, Coral ^a  

^a INSTITUT D INVESTIGACIONS BIOMÈDIQUES AUGUST PI I SUNYER IDIBAPS   (Spain)

Author keywords

Glutamate; Human neurons; Neuronal death; NMDA receptor; Polyamines; Putrescine; Spermine

Indexed keywords

DIZOCILPINE; GLUTAMIC ACID; IFENPRODIL; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; POLYAMINE DERIVATIVE; PUTRESCINE; SPERMINE;

AEROBIC METABOLISM; ANIMAL CELL; ARTICLE; ASTROCYTE; BRAIN CORTEX; CELL CULTURE; CELL DEATH; CELL SWELLING; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; EXCITOTOXICITY; GLIA; HUMAN; HUMAN CELL; NERVE CELL; NERVE CELL NECROSIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN FUNCTION; RAT;

ANIMALS; APOPTOSIS; CELLS, CULTURED; CEREBRAL CORTEX; DOSE-RESPONSE RELATIONSHIP, DRUG; EMBRYO, MAMMALIAN; HUMANS; IMMUNOHISTOCHEMISTRY; NEUROGLIA; NEURONS; PUTRESCINE; RATS; RECEPTORS, N-METHYL-D-ASPARTATE; SPERMINE;

EID: 40549089913     PISSN: 03604012     EISSN: 10974547     Source Type: Journal    
DOI: 10.1002/jnr.21538     Document Type: Article

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