Mutation of structural determinants lining the N-methyl-D-aspartate receptor channel differentially affects phencyclidine block and spermine potentiation and block

Neuroscience

Volumn 93, Issue 1, 1999, Pages 125-134

  Zheng, X ^a   Zhang, L ^a   Wang, A P ^a   Araneda, R C ^a   Lin, Y ^a   Zukin, R S ^a   Bennett, M V L ^a  

^a ALBERT EINSTEIN COLLEGE OF MEDICINE   (United States)

Author keywords

NMDA channel; Open channel block; Phencyclidine; Polyamines; Site directed mutagenesis

Indexed keywords

N METHYL DEXTRO ASPARTIC ACID RECEPTOR; PHENCYCLIDINE; SPERMINE;

AMINO ACID SUBSTITUTION; ANIMAL CELL; ARTICLE; BINDING COMPETITION; BINDING SITE; MEMBRANE CHANNEL; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; RAT; RECEPTOR BLOCKING; XENOPUS;

ALGORITHMS; AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; ANIMALS; ASPARAGINE; ELECTROPHYSIOLOGY; EXCITATORY AMINO ACID AGONISTS; EXCITATORY AMINO ACID ANTAGONISTS; MICE; MOLECULAR SEQUENCE DATA; MUTAGENESIS, SITE-DIRECTED; MUTATION; OOCYTES; PATCH-CLAMP TECHNIQUES; PHENCYCLIDINE; RATS; RECEPTORS, N-METHYL-D-ASPARTATE; SPERMINE; XENOPUS;

EID: 0032997381     PISSN: 03064522     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0306-4522(99)00154-2     Document Type: Article

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