-
1
-
-
0028015812
-
Effect of 7-nitro indazole on neurotransmission in the rat vas deferens: Mechanisms unrelated to inhibition of nitric oxide synthase
-
Allawi HS, Wallace P, Pitcher A, Gaffen Z, Bland-Ward PA, Moore PK (1994) Effect of 7-nitro indazole on neurotransmission in the rat vas deferens: mechanisms unrelated to inhibition of nitric oxide synthase. Br J Pharmacol 113:282-288
-
(1994)
Br J Pharmacol
, vol.113
, pp. 282-288
-
-
Allawi, H.S.1
Wallace, P.2
Pitcher, A.3
Gaffen, Z.4
Bland-Ward, P.A.5
Moore, P.K.6
-
2
-
-
0029914567
-
Intracellular pH and tyrosine phosphorylation but not calcium determine shear stress-induced nitric oxide production in native endothelial cells
-
Ayajiki K, Kindermann M, Hecker M, Fleming I, Busse R (1996) Intracellular pH and tyrosine phosphorylation but not calcium determine shear stress-induced nitric oxide production in native endothelial cells. Circ Res 78:750-758
-
(1996)
Circ Res
, vol.78
, pp. 750-758
-
-
Ayajiki, K.1
Kindermann, M.2
Hecker, M.3
Fleming, I.4
Busse, R.5
-
3
-
-
7344263115
-
2,4-Diamino-5,6,7,8-tetrahydro-6-(L-erythro-1,2-dihydroxypropyl)pteridine (4-ABH4) reduces nitric oxide formation and improves survival rate in experimental endotoxic shock
-
Abstract 159
-
Bahrami S, Strohmaier W, Gasser H, Peichl G, Fürst W, Fitzal F, Werner ER, Schlag G (1998) 2,4-Diamino-5,6,7,8-tetrahydro-6-(L-erythro-1,2-dihydroxypropyl)pteridine (4-ABH4) reduces nitric oxide formation and improves survival rate in experimental endotoxic shock. Shock 8 [Suppl 56]: Abstract 159
-
(1998)
Shock
, vol.8
, Issue.56 SUPPL.
-
-
Bahrami, S.1
Strohmaier, W.2
Gasser, H.3
Peichl, G.4
Fürst, W.5
Fitzal, F.6
Werner, E.R.7
Schlag, G.8
-
4
-
-
0032577582
-
Reaction of neuronal nitric oxide synthase with oxygen at low temperature. Evidence for reductive activation of the oxy-ferrous complex by tetrahydrobiopterin
-
in press
-
Bee N, Gorren ACF, Mayer B, Lange R (1998) Reaction of neuronal nitric oxide synthase with oxygen at low temperature. Evidence for reductive activation of the oxy-ferrous complex by tetrahydrobiopterin. J Biol Chem (in press)
-
(1998)
J Biol Chem
-
-
Bee, N.1
Gorren, A.C.F.2
Mayer, B.3
Lange, R.4
-
5
-
-
0029805172
-
Nitric oxide, superoxide, and peroxynitrite: The good, the bad, and the ugly
-
Beckman JS, Koppenol WH (1996) Nitric oxide, superoxide, and peroxynitrite: the good, the bad, and the ugly. Am J Physiol Cell Physiol 40:C1424-C1437
-
(1996)
Am J Physiol Cell Physiol
, vol.40
-
-
Beckman, J.S.1
Koppenol, W.H.2
-
6
-
-
0029129928
-
7-nitro indazole derivatives are potent inhibitors of brain, endothelium and inducible isoforms of nitric oxide synthase
-
Bland-Ward PA, Moore PK (1995) 7-nitro indazole derivatives are potent inhibitors of brain, endothelium and inducible isoforms of nitric oxide synthase. Life Sci 57:PL131-PL135
-
(1995)
Life Sci
, vol.57
-
-
Bland-Ward, P.A.1
Moore, P.K.2
-
7
-
-
0030606932
-
Impairment of the nitric oxide cyclic GMP pathway in cerebellar slices prepared from the hph-1 mouse
-
Brand MR Briddon A, Lund JM, Clark JB, Heales SJR (1996) Impairment of the nitric oxide cyclic GMP pathway in cerebellar slices prepared from the hph-1 mouse. Brain Res 735:169-172
-
(1996)
Brain Res
, vol.735
, pp. 169-172
-
-
Brand, M.R.1
Briddon, A.2
Lund, J.M.3
Clark, J.B.4
Heales, S.J.R.5
-
8
-
-
0026724223
-
Calmodulin is a subunit of nitric oxide synthase from macrophages
-
Cho HJ, Xie QW, Calaycay J, Mumford RA, Swiderek KM, Lee TD, Nathan C (1992) Calmodulin is a subunit of nitric oxide synthase from macrophages. J Exp Med 176:599-604
-
(1992)
J Exp Med
, vol.176
, pp. 599-604
-
-
Cho, H.J.1
Xie, Q.W.2
Calaycay, J.3
Mumford, R.A.4
Swiderek, K.M.5
Lee, T.D.6
Nathan, C.7
-
9
-
-
0028959180
-
Suppression of adjuvant-induced arthritis by selective inhibition of inducible nitric oxide synthase
-
Connor JR, Manning PT, Settle SL, Moore WM, Jerome GM, Webber RK, Tjoeng FS, Currie MG (1995) Suppression of adjuvant-induced arthritis by selective inhibition of inducible nitric oxide synthase. Eur J Pharmacol 273:15-24
-
(1995)
Eur J Pharmacol
, vol.273
, pp. 15-24
-
-
Connor, J.R.1
Manning, P.T.2
Settle, S.L.3
Moore, W.M.4
Jerome, G.M.5
Webber, R.K.6
Tjoeng, F.S.7
Currie, M.G.8
-
10
-
-
0026641944
-
Aminoguanidine, a novel inhibitor of nitric oxide formation, prevents diabetic vascular dysfunction
-
Corbett JA, Tilton RG, Chung K, Hasan KS, Ido Y, Wang JL, Sweetland MA, Lancaster JR, Williamson JR, McDaniel ML (1992) Aminoguanidine, a novel inhibitor of nitric oxide formation, prevents diabetic vascular dysfunction. Diabetes 41:552-556
-
(1992)
Diabetes
, vol.41
, pp. 552-556
-
-
Corbett, J.A.1
Tilton, R.G.2
Chung, K.3
Hasan, K.S.4
Ido, Y.5
Wang, J.L.6
Sweetland, M.A.7
Lancaster, J.R.8
Williamson, J.R.9
McDaniel, M.L.10
-
11
-
-
0030723329
-
The structure of nitric oxide synthase oxygenase domain and inhibitor complexes
-
Crane BR, Arvai AS, Gachhui R, Wu CQ, Ghosh DK, Getzoff ED, Stuehr DJ, Tainer JA (1997) The structure of nitric oxide synthase oxygenase domain and inhibitor complexes. Science 278:425-131
-
(1997)
Science
, vol.278
, pp. 425-1131
-
-
Crane, B.R.1
Arvai, A.S.2
Gachhui, R.3
Wu, C.Q.4
Ghosh, D.K.5
Getzoff, E.D.6
Stuehr, D.J.7
Tainer, J.A.8
-
12
-
-
0032571411
-
Structure of nitric oxide synthase oxygenase dinier with pterin and substrate
-
Crane BR, Arvai AS, Ghosh DK, Wu CQ, Getzoff ED, Stuehr DJ, Tainer JA (1998) Structure of nitric oxide synthase oxygenase dinier with pterin and substrate. Science 279:2121-2126
-
(1998)
Science
, vol.279
, pp. 2121-2126
-
-
Crane, B.R.1
Arvai, A.S.2
Ghosh, D.K.3
Wu, C.Q.4
Getzoff, E.D.5
Stuehr, D.J.6
Tainer, J.A.7
-
14
-
-
0030914284
-
Neuronal nitric oxide synthase alternatively spliced forms: Prominent functional localizations in the brain
-
Eliasson MJL, Blackshaw S, Schell MJ, Snyder SH (1997) Neuronal nitric oxide synthase alternatively spliced forms: prominent functional localizations in the brain. Proc Natl Acad Sci USA 94:3396-3401
-
(1997)
Proc Natl Acad Sci USA
, vol.94
, pp. 3396-3401
-
-
Eliasson, M.J.L.1
Blackshaw, S.2
Schell, M.J.3
Snyder, S.H.4
-
15
-
-
0027458692
-
Irreversible inhibition of macrophage and brain nitric oxide synthase by L-NG-methylarginine requires NADPH-dependent hydroxylation
-
Feldman PL, Griffith OW, Hong H, Stuehr DJ (1993) Irreversible inhibition of macrophage and brain nitric oxide synthase by L-NG-methylarginine requires NADPH-dependent hydroxylation. J Med Chem 36:491-496
-
(1993)
J Med Chem
, vol.36
, pp. 491-496
-
-
Feldman, P.L.1
Griffith, O.W.2
Hong, H.3
Stuehr, D.J.4
-
16
-
-
0028818035
-
Nitric oxide synthase: Expression and expressional control of the three isoforms
-
Förstermann U, Kleinert H (1995) Nitric oxide synthase: expression and expressional control of the three isoforms. Naunyn Schmiedebergs Arch Pharmacol 352:351-364
-
(1995)
Naunyn Schmiedebergs Arch Pharmacol
, vol.352
, pp. 351-364
-
-
Förstermann, U.1
Kleinert, H.2
-
17
-
-
0028172940
-
L-Thiocitrulline - A stereospecific, hemebinding inhibitor of nitric-oxide synthases
-
Frey C, Narayanan K, McMillan K, Spack L, Gross SS, Masters BS, Griffith OW (1994) L-Thiocitrulline - a stereospecific, hemebinding inhibitor of nitric-oxide synthases. J Biol Chem 269:26083-26091
-
(1994)
J Biol Chem
, vol.269
, pp. 26083-26091
-
-
Frey, C.1
Narayanan, K.2
McMillan, K.3
Spack, L.4
Gross, S.S.5
Masters, B.S.6
Griffith, O.W.7
-
18
-
-
0028987869
-
Inhibition of constitutive and inducible nitric oxide synthase: Potential selective inhibition
-
Fukuto JM, Chaudhuri G (1995) Inhibition of constitutive and inducible nitric oxide synthase: potential selective inhibition. Annu Rev Pharmacol Toxicol 35:165-194
-
(1995)
Annu Rev Pharmacol Toxicol
, vol.35
, pp. 165-194
-
-
Fukuto, J.M.1
Chaudhuri, G.2
-
19
-
-
0027184034
-
Selective inhibition of constitutive nitric oxide synthase by L-N(G)-nitroarginine
-
Furfine ES, Harmon MF, Paith JE, Garvcy EP (1993) Selective inhibition of constitutive nitric oxide synthase by L-N(G)-nitroarginine. Biochemistry 32:8512-8517
-
(1993)
Biochemistry
, vol.32
, pp. 8512-8517
-
-
Furfine, E.S.1
Harmon, M.F.2
Paith, J.E.3
Garvcy, E.P.4
-
20
-
-
0024296032
-
Endothelium-derived relaxing factor release on activation of NMDA receptors suggests role as intercellular messenger in the brain
-
Gurthwaite J, Charles SL, Chess-Williams R (1988) Endothelium-derived relaxing factor release on activation of NMDA receptors suggests role as intercellular messenger in the brain. Nature 336:385-388
-
(1988)
Nature
, vol.336
, pp. 385-388
-
-
Gurthwaite, J.1
Charles, S.L.2
Chess-Williams, R.3
-
21
-
-
0028089793
-
Potent and selective inhibition of human nitric oxide synthases - Inhibition by non-amino acid isothioureas
-
Garvey EP, Oplinger JA, Tanoury GJ, Sherman PA, Fowler M, Marshall S, Harmon MF, Paith JE, Furfine ES (1994) Potent and selective inhibition of human nitric oxide synthases - inhibition by non-amino acid isothioureas. J Biol Chem 269:26669-26676
-
(1994)
J Biol Chem
, vol.269
, pp. 26669-26676
-
-
Garvey, E.P.1
Oplinger, J.A.2
Tanoury, G.J.3
Sherman, P.A.4
Fowler, M.5
Marshall, S.6
Harmon, M.F.7
Paith, J.E.8
Furfine, E.S.9
-
22
-
-
0031040613
-
1400W is a slow, tight binding, and highly selective inhibitor of inducible nitric-oxide synthase in vitro and in vivo
-
Garvey EP, Oplinger JA, Furfine ES, Kiff RJ, Luszlo F, Whittle BJR, Knowles RG (1997) 1400W is a slow, tight binding, and highly selective inhibitor of inducible nitric-oxide synthase in vitro and in vivo. J Biol Chem 272:4959-4963
-
(1997)
J Biol Chem
, vol.272
, pp. 4959-4963
-
-
Garvey, E.P.1
Oplinger, J.A.2
Furfine, E.S.3
Kiff, R.J.4
Luszlo, F.5
Whittle, B.J.R.6
Knowles, R.G.7
-
24
-
-
0029788361
-
Role of a coppert(I)-dependent enzyme in the anti-platelet action of S-nitrosoglutathione
-
Gordge MP, Hothersall JS, Neild GH, Dutra AAN (1996) Role of a coppert(I)-dependent enzyme in the anti-platelet action of S-nitrosoglutathione. Br J Pharmacol 119:533-538
-
(1996)
Br J Pharmacol
, vol.119
, pp. 533-538
-
-
Gordge, M.P.1
Hothersall, J.S.2
Neild, G.H.3
Dutra, A.A.N.4
-
25
-
-
0030464496
-
Pteridine-free neuronal nitricoxide synthase: Evidence for two identical highly anticooperative tetrahydrobiopterin binding sites
-
Gorren ACF, List BM, Schrammel A, Fitters E, Hemmens B, Werner ER, Schmidt K, Mayer B (1996a) Pteridine-free neuronal nitricoxide synthase: evidence for two identical highly anticooperative tetrahydrobiopterin binding sites. Biochemistry 35:16735-16745
-
(1996)
Biochemistry
, vol.35
, pp. 16735-16745
-
-
Gorren, A.C.F.1
List, B.M.2
Schrammel, A.3
Fitters, E.4
Hemmens, B.5
Werner, E.R.6
Schmidt, K.7
Mayer, B.8
-
26
-
-
0030010784
-
Decomposition of S-nitrosoglutathione in the presence of copper and glutathione
-
Gorren ACF, Schrammel A, Schmidt K, Mayer B (1996b) Decomposition of S-nitrosoglutathione in the presence of copper and glutathione. Arch Biochem Biophys 330:219-228
-
(1996)
Arch Biochem Biophys
, vol.330
, pp. 219-228
-
-
Gorren, A.C.F.1
Schrammel, A.2
Schmidt, K.3
Mayer, B.4
-
27
-
-
0030894594
-
Thiols and neuronal nitric oxide synthase: Complex formation, competitive inhibition, and enzyme stabilisation
-
Gorren ACF, Schrammel A, Schmidt K, Mayer B (1997) Thiols and neuronal nitric oxide synthase: complex formation, competitive inhibition, and enzyme stabilisation. Biochemistry 36:4360-4366
-
(1997)
Biochemistry
, vol.36
, pp. 4360-4366
-
-
Gorren, A.C.F.1
Schrammel, A.2
Schmidt, K.3
Mayer, B.4
-
28
-
-
0026584089
-
Ca2+/calmodulin-dependent formation of hydrogen peroxide by brain nitric oxide synthase
-
Heinzel B, John M, Klatt P, Böhme H, Mayer B (1992) Ca2+/calmodulin-dependent formation of hydrogen peroxide by brain nitric oxide synthase. Biochem J 281:627-630
-
(1992)
Biochem J
, vol.281
, pp. 627-630
-
-
Heinzel, B.1
John, M.2
Klatt, P.3
Böhme, H.4
Mayer, B.5
-
29
-
-
0032227694
-
Enzymology of nitric oxide synthases
-
Titheradge MA (ed) Humana Press, Totowa
-
Hemmens B, Mayer B (1997) Enzymology of nitric oxide synthases. In: Titheradge MA (ed) Methods in molecular biology. Humana Press, Totowa, pp 1-32
-
(1997)
Methods in Molecular Biology
, pp. 1-32
-
-
Hemmens, B.1
Mayer, B.2
-
30
-
-
0027945658
-
Effects of cerebral ischemia in mice deficient in neuronal nitric oxide synthase
-
Huang ZH, Huang PL, Panahian N, Dalkara T, Kishman MC, Moskowitz MA (1994) Effects of cerebral ischemia in mice deficient in neuronal nitric oxide synthase. Science 265:1883-1885
-
(1994)
Science
, vol.265
, pp. 1883-1885
-
-
Huang, Z.H.1
Huang, P.L.2
Panahian, N.3
Dalkara, T.4
Kishman, M.C.5
Moskowitz, M.A.6
-
31
-
-
0028302095
-
The pteridine binding site of brain nitric oxide synthase -tetrahydrobiopterin binding kinetics, specificity, and allosteric interaction with the substrate domain
-
Klatt P, Schmid M, Leopold E, Schmidt K, Werner BR, Mayer B (1994a) The pteridine binding site of brain nitric oxide synthase -tetrahydrobiopterin binding kinetics, specificity, and allosteric interaction with the substrate domain. J Biol Chem 269:13861-13866
-
(1994)
J Biol Chem
, vol.269
, pp. 13861-13866
-
-
Klatt, P.1
Schmid, M.2
Leopold, E.3
Schmidt, K.4
Werner, B.R.5
Mayer, B.6
-
32
-
-
0028140141
-
Inhibitors of brain nitric oxide synthase. Binding kinetics, metabolism, and enzyme inactivation
-
Klatt P, Schmidt K, Brunner F, Mayer B (1994b) Inhibitors of brain nitric oxide synthase. Binding kinetics, metabolism, and enzyme inactivation. J Biol Chem 269:1674-1680
-
(1994)
J Biol Chem
, vol.269
, pp. 1674-1680
-
-
Klatt, P.1
Schmidt, K.2
Brunner, F.3
Mayer, B.4
-
33
-
-
0029125762
-
Structural analysis of porcine brain nitric oxide synthase reveals novel role of tetrahydrobiopterin and L-arginine in the formation of an SDS-resistant dimer
-
Klatt P, Schmidt K, Lehner D, Glatter O, Bächinger HP, Mayer B (1995) Structural analysis of porcine brain nitric oxide synthase reveals novel role of tetrahydrobiopterin and L-arginine in the formation of an SDS-resistant dimer. EMBO J 14:3687-3695
-
(1995)
EMBO J
, vol.14
, pp. 3687-3695
-
-
Klatt, P.1
Schmidt, K.2
Lehner, D.3
Glatter, O.4
Bächinger, H.P.5
Mayer, B.6
-
34
-
-
0030948345
-
Characterization of bovine endothelial nitric oxide synthase as a homodimer with down-regulated uncoupled NADPH oxidase activity: Tetrahydrobiopterin binding kinetics and role of haem in dimerization
-
List BM, Klösch B, Völker C, Gorren ACF, Sessa WC, Werner ER, Kukovetz WR, Schmidt K, Mayer B (1997) Characterization of bovine endothelial nitric oxide synthase as a homodimer with down-regulated uncoupled NADPH oxidase activity: tetrahydrobiopterin binding kinetics and role of haem in dimerization. Biochem J 323:159-165
-
(1997)
Biochem J
, vol.323
, pp. 159-165
-
-
List, B.M.1
Klösch, B.2
Völker, C.3
Gorren, A.C.F.4
Sessa, W.C.5
Werner, E.R.6
Kukovetz, W.R.7
Schmidt, K.8
Mayer, B.9
-
35
-
-
0027941257
-
Synaptic plasticity in the hippocampus: LTP and LTD
-
Malenka RC (1994) Synaptic plasticity in the hippocampus: LTP and LTD, Cell 78:535-538
-
(1994)
Cell
, vol.78
, pp. 535-538
-
-
Malenka, R.C.1
-
36
-
-
0030694038
-
Biosynthesis and action of nitric oxide in mammalian cells
-
Mayer B, Hemmens B (1997) Biosynthesis and action of nitric oxide in mammalian cells. Trends Biochem Sci 22:477-481
-
(1997)
Trends Biochem Sci
, vol.22
, pp. 477-481
-
-
Mayer, B.1
Hemmens, B.2
-
37
-
-
0029043644
-
In search of a function for tetrahydrobiopterin in the biosynthesis of nitric oxide
-
Mayer B, Werner ER (1995) In search of a function for tetrahydrobiopterin in the biosynthesis of nitric oxide. Naunyn Schmiedebergs Arch Pharmacol 351:453-463
-
(1995)
Naunyn Schmiedebergs Arch Pharmacol
, vol.351
, pp. 453-463
-
-
Mayer, B.1
Werner, E.R.2
-
38
-
-
0028034105
-
Molecular mechanism of inhibition of porcine brain nitric oxide synthase by the antinociceptive drug 7-nitroindazole
-
Mayer B, Klatt P, Werner ER, Schmidt K (1994) Molecular mechanism of inhibition of porcine brain nitric oxide synthase by the antinociceptive drug 7-nitroindazole. Neuropharmacology 33:1253-1259
-
(1994)
Neuropharmacology
, vol.33
, pp. 1253-1259
-
-
Mayer, B.1
Klatt, P.2
Werner, E.R.3
Schmidt, K.4
-
39
-
-
0030793667
-
Tetrahydrobiopterin binding to inducible nitric oxide synthase expressed in Escherichia coli. Heme spin shift and dimer stabilization by the potent pterin antagonist 4-amino-tetrahydrobiopterin
-
Mayer B, Wu C, Gorren ACF, Pfeitfer S, Schmidt K, Clark P, Stuehr DJ, Werner ER (1997) Tetrahydrobiopterin binding to inducible nitric oxide synthase expressed in Escherichia coli. Heme spin shift and dimer stabilization by the potent pterin antagonist 4-amino-tetrahydrobiopterin. Biochemistry 36:8422-8427
-
(1997)
Biochemistry
, vol.36
, pp. 8422-8427
-
-
Mayer, B.1
Wu, C.2
Gorren, A.C.F.3
Pfeitfer, S.4
Schmidt, K.5
Clark, P.6
Stuehr, D.J.7
Werner, E.R.8
-
40
-
-
0032488967
-
A new pathway of nitric oxide/cyclic GMP signaling involving S-nitrosoglutathione
-
Mayer B, Pfeiffer S, Schrammel A, Schmidt K, Koesling D, Brunner F (1998) A new pathway of nitric oxide/cyclic GMP signaling involving S-nitrosoglutathione. J Biol Chem 273:3264-3270
-
(1998)
J Biol Chem
, vol.273
, pp. 3264-3270
-
-
Mayer, B.1
Pfeiffer, S.2
Schrammel, A.3
Schmidt, K.4
Koesling, D.5
Brunner, F.6
-
41
-
-
0027402115
-
Selective inhibition of the inducible nitric oxide synthase by aminoguanidine
-
Misko TP, Moore WM, Kasten TP, Nickols GA, Corbett JA, Tilton RG, McDaniel ML, Williamson JR, Currie MG (1993) Selective inhibition of the inducible nitric oxide synthase by aminoguanidine. Eur J Pharmacol 233:119-125
-
(1993)
Eur J Pharmacol
, vol.233
, pp. 119-125
-
-
Misko, T.P.1
Moore, W.M.2
Kasten, T.P.3
Nickols, G.A.4
Corbett, J.A.5
Tilton, R.G.6
McDaniel, M.L.7
Williamson, J.R.8
Currie, M.G.9
-
42
-
-
0025883342
-
Nitric oxide - Physiology, pathophysiology, and pharmacology
-
Moncada S, Palmer RMJ, Higgs EA (1991) Nitric oxide - physiology, pathophysiology, and pharmacology. Pharmacol Rev 43:109-142
-
(1991)
Pharmacol Rev
, vol.43
, pp. 109-142
-
-
Moncada, S.1
Palmer, R.M.J.2
Higgs, E.A.3
-
43
-
-
0030795934
-
Selective inhibitors of neuronal nitric oxide synthase - Is no NOS really good NOS for the nervous system?
-
Moore PK, Handy RLC (1997) Selective inhibitors of neuronal nitric oxide synthase - is no NOS really good NOS for the nervous system? Trends Pharmacol Sci 18:204-211
-
(1997)
Trends Pharmacol Sci
, vol.18
, pp. 204-211
-
-
Moore, P.K.1
Handy, R.L.C.2
-
44
-
-
0027404419
-
7-Nitro indazole, an inhibitor of nitric oxide synthase, exhibits antinociceptive activity in the mouse without increasing blood pressure
-
Moore PK, Babbedge RC, Wallace P, Gaffen ZA, Hart SL (1993) 7-Nitro indazole, an inhibitor of nitric oxide synthase, exhibits antinociceptive activity in the mouse without increasing blood pressure. Br J Pharmacol 108:296-297
-
(1993)
Br J Pharmacol
, vol.108
, pp. 296-297
-
-
Moore, P.K.1
Babbedge, R.C.2
Wallace, P.3
Gaffen, Z.A.4
Hart, S.L.5
-
45
-
-
0028173010
-
L-N-6-(1-iminoethyl)lysine: A selective inhibitor of inducible nitric oxide synthase
-
Moore WM, Webber RK, Jerome GM, Tjoeng FS, Misko TP, Currie MG (1994) L-N-6-(1-iminoethyl)lysine: a selective inhibitor of inducible nitric oxide synthase. J Med Chem 37:3886-3888
-
(1994)
J Med Chem
, vol.37
, pp. 3886-3888
-
-
Moore, W.M.1
Webber, R.K.2
Jerome, G.M.3
Tjoeng, F.S.4
Misko, T.P.5
Currie, M.G.6
-
46
-
-
0028968360
-
Novel potent and selective inhibitors of inducible nitric oxide synthase
-
Nakane M, Klinghofer V, Kuk JE, Donnelly JL, Budzik GP, Pollock JS, Basha F, Carter GW (1995) Novel potent and selective inhibitors of inducible nitric oxide synthase. Mol Pharmacol 47:831-834
-
(1995)
Mol Pharmacol
, vol.47
, pp. 831-834
-
-
Nakane, M.1
Klinghofer, V.2
Kuk, J.E.3
Donnelly, J.L.4
Budzik, G.P.5
Pollock, J.S.6
Basha, F.7
Carter, G.W.8
-
47
-
-
0029078058
-
S-alkyl-L-thiocitrullines - Potent stereoselective inhibitors of nitric oxide synthase with strong pressor activity in vivo
-
Narayanan K, Spack L, McMillan K, Kilbourn RG, Hayward MA, Masters BSS, Griffith OW (1995) S-alkyl-L-thiocitrullines - potent stereoselective inhibitors of nitric oxide synthase with strong pressor activity in vivo. J Biol Chem 270:11103-11110
-
(1995)
J Biol Chem
, vol.270
, pp. 11103-11110
-
-
Narayanan, K.1
Spack, L.2
McMillan, K.3
Kilbourn, R.G.4
Hayward, M.A.5
Masters, B.S.S.6
Griffith, O.W.7
-
48
-
-
0027339884
-
G-Methyl-L-arginine functions as an alternate substrate and mechanism-based inhibitor of nitric oxide synthase
-
G-Methyl-L-arginine functions as an alternate substrate and mechanism-based inhibitor of nitric oxide synthase. Biochemistry 32:9677-9685
-
(1993)
Biochemistry
, vol.32
, pp. 9677-9685
-
-
Olken, N.M.1
Marietta, M.A.2
-
49
-
-
0030008814
-
Effect of scrapie infection on the activity of neuronal nitric-oxide synthase in brain and neuroblastoma cells
-
Ovadia H, Rosenmann H, Shezen E, Halimi M, Ofran I, Gabizon R (1996) Effect of scrapie infection on the activity of neuronal nitric-oxide synthase in brain and neuroblastoma cells. J Biol Chem 271:16856-16861
-
(1996)
J Biol Chem
, vol.271
, pp. 16856-16861
-
-
Ovadia, H.1
Rosenmann, H.2
Shezen, E.3
Halimi, M.4
Ofran, I.5
Gabizon, R.6
-
50
-
-
0029888810
-
Inhibition of nitric oxide synthesis by N-G-nitro-L-arginine methyl ester (L-NAME): Requirement for bioactivation to the free acid, N-G-nitro-L-arginine
-
Pfeiffer S, Leopold E, Schmidt K, Brunner F, Mayer B (1996) Inhibition of nitric oxide synthesis by N-G-nitro-L-arginine methyl ester (L-NAME): requirement for bioactivation to the free acid, N-G-nitro-L-arginine. Br J Pharmacol 118:1433-1440
-
(1996)
Br J Pharmacol
, vol.118
, pp. 1433-1440
-
-
Pfeiffer, S.1
Leopold, E.2
Schmidt, K.3
Brunner, F.4
Mayer, B.5
-
51
-
-
0030687876
-
Allosteric modulation of neuronal nitric oxide synthase by the pterin-site inhibitor 4-amino-tetrahydrobiopterin
-
Pfeiffer S, Gorren ACF, Pitters E, Schmidt K, Werner ER, Mayer B (1997) Allosteric modulation of neuronal nitric oxide synthase by the pterin-site inhibitor 4-amino-tetrahydrobiopterin. Biochem J 328:349-352
-
(1997)
Biochem J
, vol.328
, pp. 349-352
-
-
Pfeiffer, S.1
Gorren, A.C.F.2
Pitters, E.3
Schmidt, K.4
Werner, E.R.5
Mayer, B.6
-
52
-
-
0032488596
-
Comparative functioning of dihydro- and tetrahydropterins in supporting electron transfer, catalysis, and subunit dimerization in inducible nitric oxide synthase
-
Presta A, Siddhanta U, Wu CQ, Sennequier N, Huang LX, AbuSoud HM, Erzurum S, Stuehr DJ (1998) Comparative functioning of dihydro- and tetrahydropterins in supporting electron transfer, catalysis, and subunit dimerization in inducible nitric oxide synthase. Biochemistry 37:298-310
-
(1998)
Biochemistry
, vol.37
, pp. 298-310
-
-
Presta, A.1
Siddhanta, U.2
Wu, C.Q.3
Sennequier, N.4
Huang, L.X.5
AbuSoud, H.M.6
Erzurum, S.7
Stuehr, D.J.8
-
53
-
-
0030715301
-
An autoinhibitory control element defines calcium-regulated isotorms of nitric oxide synthase
-
Salerno JC, Harris DE, Irizarry K, Patel B, Morales AJ, Smith SME, Martasek P, Roman LJ, Masters BSS, Jones CL, Weissman BA, Lane P, Liu Q, Gross SS (1997) An autoinhibitory control element defines calcium-regulated isotorms of nitric oxide synthase. J Biol Chem 272:29769-29777
-
(1997)
J Biol Chem
, vol.272
, pp. 29769-29777
-
-
Salerno, J.C.1
Harris, D.E.2
Irizarry, K.3
Patel, B.4
Morales, A.J.5
Smith, S.M.E.6
Martasek, P.7
Roman, L.J.8
Masters, B.S.S.9
Jones, C.L.10
Weissman, B.A.11
Lane, P.12
Liu, Q.13
Gross, S.S.14
-
54
-
-
7344267092
-
Tetrahydrobiopterin-antagonists: A novel class of NO synthase inhibitors
-
Abstract 97
-
Schenk H, Hofmann H, Sennefelder H, Groehn V, Pfleiderer W, Schmidt HHHW ( 1996) Tetrahydrobiopterin-antagonists: a novel class of NO synthase inhibitors. Naunyn Schmiedebergs Arch Pharmacol 353 [Suppl]:R32 (Abstract 97)
-
(1996)
Naunyn Schmiedebergs Arch Pharmacol
, vol.353
, Issue.SUPPL.
-
-
Schenk, H.1
Hofmann, H.2
Sennefelder, H.3
Groehn, V.4
Pfleiderer, W.5
Schmidt, H.H.H.W.6
-
56
-
-
85046499251
-
Activation of soluble guanyly! cyclase by the nitrovusodilator SIN-1 involves formation of S-nitrosoglutathione
-
in press
-
Schrammel A, Pfeiffer S, Schmidt K, Koesling D, Mayer B (1998) Activation of soluble guanyly! cyclase by the nitrovusodilator SIN-1 involves formation of S-nitrosoglutathione. Mol Pharmacol 96 (in press)
-
(1998)
Mol Pharmacol
, vol.96
-
-
Schrammel, A.1
Pfeiffer, S.2
Schmidt, K.3
Koesling, D.4
Mayer, B.5
-
57
-
-
0028796770
-
Inhibition of neuronal nitric oxide synthase by 7-nitroindazole protects against MPTP-induced neurotoxicity in mice
-
Schulz JB, Matthews RT, Muqit MMK, Browne SE, Beal MF (1995) Inhibition of neuronal nitric oxide synthase by 7-nitroindazole protects against MPTP-induced neurotoxicity in mice. J Neurochem 64:936-939
-
(1995)
J Neurochem
, vol.64
, pp. 936-939
-
-
Schulz, J.B.1
Matthews, R.T.2
Muqit, M.M.K.3
Browne, S.E.4
Beal, M.F.5
-
58
-
-
0030979486
-
Substituted N-phenylisothioureas: Potent inhibitors of human nitric oxide synthase with neuronal isoform selectivity
-
Shearer BG, Lee SL, Oplinger JA, Frick LW, Garvey EP, Furfine ES (1997) Substituted N-phenylisothioureas: potent inhibitors of human nitric oxide synthase with neuronal isoform selectivity. J Med Chem 40:1901-1905
-
(1997)
J Med Chem
, vol.40
, pp. 1901-1905
-
-
Shearer, B.G.1
Lee, S.L.2
Oplinger, J.A.3
Frick, L.W.4
Garvey, E.P.5
Furfine, E.S.6
-
59
-
-
0030040255
-
Selective pharmacological inhibition of distinct nitric oxide synthase isoforms
-
Southan GJ, Szabo C (1996) Selective pharmacological inhibition of distinct nitric oxide synthase isoforms. Biochem Pharmacol 51:383-394
-
(1996)
Biochem Pharmacol
, vol.51
, pp. 383-394
-
-
Southan, G.J.1
Szabo, C.2
-
61
-
-
0030988217
-
Structure-function aspects in the nitric oxide synthases
-
Stuehr DJ (1997) Structure-function aspects in the nitric oxide synthases. Annu Rev Pharmacol Toxicol 37:339-359
-
(1997)
Annu Rev Pharmacol Toxicol
, vol.37
, pp. 339-359
-
-
Stuehr, D.J.1
-
62
-
-
0028577721
-
Beneficial effects and improved survival in rodent models of septic shock with S-methylisothiourea sulfate, a potent and selective inhibitor of inducible nitric oxide synthase
-
Szabo C, Southan GJ, Thiemermann C (1994) Beneficial effects and improved survival in rodent models of septic shock with S-methylisothiourea sulfate, a potent and selective inhibitor of inducible nitric oxide synthase. Proc Natl Acad Sci USA 91:12472-12476
-
(1994)
Proc Natl Acad Sci USA
, vol.91
, pp. 12472-12476
-
-
Szabo, C.1
Southan, G.J.2
Thiemermann, C.3
-
63
-
-
0029827739
-
Identification of the 4-amino analogue of tetrahydrobiopterin as dihydropteridine reductase inhibitor and potent pteridine antagonist of rat neuronal nitric oxide synthase
-
Werner ER, Pitters E, Schmidt K, Wachter H, Werner-Felmayer G, Mayer B (1996) Identification of the 4-amino analogue of tetrahydrobiopterin as dihydropteridine reductase inhibitor and potent pteridine antagonist of rat neuronal nitric oxide synthase. Biochem J 320:193-196
-
(1996)
Biochem J
, vol.320
, pp. 193-196
-
-
Werner, E.R.1
Pitters, E.2
Schmidt, K.3
Wachter, H.4
Werner-Felmayer, G.5
Mayer, B.6
-
64
-
-
0025151263
-
Concerted action of reduced glutathione and superoxide dismutase in preventing redox cycling of dihydroxypyrimidines, and their role in antioxidant defence
-
Winterbourn CC, Munday R (1990) Concerted action of reduced glutathione and superoxide dismutase in preventing redox cycling of dihydroxypyrimidines, and their role in antioxidant defence. Free Radic Biol Med 8:287-293
-
(1990)
Free Radic Biol Med
, vol.8
, pp. 287-293
-
-
Winterbourn, C.C.1
Munday, R.2
-
65
-
-
0028893884
-
Aminoguanidine is an isoform-selective, mechanism-based inactivator of nitric oxide synthuse
-
Wolff DJ, Lubeskie A (1995) Aminoguanidine is an isoform-selective, mechanism-based inactivator of nitric oxide synthuse. Arch Biochem Biophys 316:290-301
-
(1995)
Arch Biochem Biophys
, vol.316
, pp. 290-301
-
-
Wolff, D.J.1
Lubeskie, A.2
-
66
-
-
0030808463
-
Inactivation of nitric oxide synthase by substituted aminoguanidines and amino-isothioureas
-
Wolff DJ, Gauld DS, Neulander MJ, Southan G (1997) Inactivation of nitric oxide synthase by substituted aminoguanidines and amino-isothioureas. J Pharmacol Exp Ther 283:265-273
-
(1997)
J Pharmacol Exp Ther
, vol.283
, pp. 265-273
-
-
Wolff, D.J.1
Gauld, D.S.2
Neulander, M.J.3
Southan, G.4
-
67
-
-
0028035106
-
The high-output nitric oxide pathway: Role and regulation
-
Xie QW, Nathan C (1994) The high-output nitric oxide pathway: role and regulation. J Leukoc Biol 56:576-582
-
(1994)
J Leukoc Biol
, vol.56
, pp. 576-582
-
-
Xie, Q.W.1
Nathan, C.2
-
68
-
-
0027942138
-
The NOS inhibitor, 7-nitroindazole, decreases focal infarct volume but not the response to topical acetylcholine in pial vessels
-
Yoshida T, Limmroth V, Irikura K, Moskowitz MA (1994) The NOS inhibitor, 7-nitroindazole, decreases focal infarct volume but not the response to topical acetylcholine in pial vessels. J Cereb Blood Flow Metab 14:924-929
-
(1994)
J Cereb Blood Flow Metab
, vol.14
, pp. 924-929
-
-
Yoshida, T.1
Limmroth, V.2
Irikura, K.3
Moskowitz, M.A.4
-
69
-
-
0029934405
-
ARL 17477. A potent and selective neuronal NOS inhibitor, decreases infarct volume after transient middle cerebral artery occlusion in rats
-
Zhang ZG, Reif D, MacDonald J, Tang WX, Kamp DK, Gentile RJ, Shakespeare WC, Murray RJ, Chopp M (1996) ARL 17477. a potent and selective neuronal NOS inhibitor, decreases infarct volume after transient middle cerebral artery occlusion in rats. J Cereb Blood Flow Metab 16:599-604
-
(1996)
J Cereb Blood Flow Metab
, vol.16
, pp. 599-604
-
-
Zhang, Z.G.1
Reif, D.2
MacDonald, J.3
Tang, W.X.4
Kamp, D.K.5
Gentile, R.J.6
Shakespeare, W.C.7
Murray, R.J.8
Chopp, M.9
|