-
2
-
-
84936985434
-
Hypoxia and prostate cancer aggressiveness: A tale with many endings
-
Fraga A, Ribeiro R, Principe P, Lopes C, Medeiros R. Hypoxia and prostate cancer aggressiveness: a tale with many endings. Clin Genitourinary Cancer. 2015;13:295-301.
-
(2015)
Clin Genitourinary Cancer
, vol.13
, pp. 295-301
-
-
Fraga, A.1
Ribeiro, R.2
Principe, P.3
Lopes, C.4
Medeiros, R.5
-
3
-
-
47049091483
-
Hypoxia selects for androgen independent LNCaP cells with a more malignant geno- and phenotype
-
Butterworth KT, McCarthy HO, Devlin A, Ming L, Robson T, McKeown SR, Worthington J. Hypoxia selects for androgen independent LNCaP cells with a more malignant geno- and phenotype. Int J Cancer. 2008;123:760-8.
-
(2008)
Int J Cancer
, vol.123
, pp. 760-768
-
-
Butterworth, K.T.1
McCarthy, H.O.2
Devlin, A.3
Ming, L.4
Robson, T.5
McKeown, S.R.6
Worthington, J.7
-
4
-
-
72149123186
-
The relevance of a hypoxic tumour microenvironment in prostate cancer
-
Stewart GD, Ross JA, McLaren DB, Parker CC, Habib FK, Riddick AC. The relevance of a hypoxic tumour microenvironment in prostate cancer. BJU Int. 2010;105:8-13.
-
(2010)
BJU Int
, vol.105
, pp. 8-13
-
-
Stewart, G.D.1
Ross, J.A.2
McLaren, D.B.3
Parker, C.C.4
Habib, F.K.5
Riddick, A.C.6
-
5
-
-
84912096468
-
Antiangiogenesis strategies revisited: From starving tumors to alleviating hypoxia
-
Jain RK. Antiangiogenesis strategies revisited: from starving tumors to alleviating hypoxia. Cancer Cell. 2014;26:605-22.
-
(2014)
Cancer Cell
, vol.26
, pp. 605-622
-
-
Jain, R.K.1
-
6
-
-
0036359548
-
Hypoxia--a key regulatory factor in tumour growth
-
Harris AL. Hypoxia--a key regulatory factor in tumour growth. Nat Rev Cancer. 2002;2:38-47.
-
(2002)
Nat Rev Cancer
, vol.2
, pp. 38-47
-
-
Harris, A.L.1
-
7
-
-
84872467458
-
The role of hypoxia-inducible factor 1alpha in determining the properties of castrate-resistant prostate cancers
-
Ranasinghe WK, Xiao L, Kovac S, Chang M, Michiels C, Bolton D, Shulkes A, Baldwin GS, Patel O. The role of hypoxia-inducible factor 1alpha in determining the properties of castrate-resistant prostate cancers. PloS One. 2013;8:e54251.
-
(2013)
Plos One
, vol.8
, pp. 54251
-
-
Ranasinghe, W.K.1
Xiao, L.2
Kovac, S.3
Chang, M.4
Michiels, C.5
Bolton, D.6
Shulkes, A.7
Baldwin, G.S.8
Patel, O.9
-
8
-
-
84921981432
-
The tumour hypoxia marker pimonidazole reflects a transcriptional programme associated with aggressive prostate cancer
-
Ragnum HB, Vlatkovic L, Lie AK, Axcrona K, Julin CH, Frikstad KM, Hole KH, Seierstad T, Lyng H. The tumour hypoxia marker pimonidazole reflects a transcriptional programme associated with aggressive prostate cancer. Br J Cancer. 2015;112:382-90.
-
(2015)
Br J Cancer
, vol.112
, pp. 382-390
-
-
Ragnum, H.B.1
Vlatkovic, L.2
Lie, A.K.3
Axcrona, K.4
Julin, C.H.5
Frikstad, K.M.6
Hole, K.H.7
Seierstad, T.8
Lyng, H.9
-
9
-
-
84859408670
-
Tumor hypoxia predicts biochemical failure following radiotherapy for clinically localized prostate cancer
-
Milosevic M, Warde P, Menard C, Chung P, Toi A, Ishkanian A, McLean M, Pintilie M, Sykes J, Gospodarowicz M, Catton C, Hill RP, Bristow R. Tumor hypoxia predicts biochemical failure following radiotherapy for clinically localized prostate cancer. Clin Cancer Res. 2012;18:2108-14.
-
(2012)
Clin Cancer Res
, vol.18
, pp. 2108-2114
-
-
Milosevic, M.1
Warde, P.2
Menard, C.3
Chung, P.4
Toi, A.5
Ishkanian, A.6
McLean, M.7
Pintilie, M.8
Sykes, J.9
Gospodarowicz, M.10
Catton, C.11
Hill, R.P.12
Bristow, R.13
-
10
-
-
40949120482
-
Intrinsic markers of tumour hypoxia and angiogenesis in localised prostate cancer and outcome of radical treatment: A retrospective analysis of two randomised radiotherapy trials and one surgical cohort study
-
Vergis R, Corbishley CM, Norman AR, Bartlett J, Jhavar S, Borre M, Heeboll S, Horwich A, Huddart R, Khoo V, Eeles R, Cooper C, Sydes M, Dearnaley D, Parker C. Intrinsic markers of tumour hypoxia and angiogenesis in localised prostate cancer and outcome of radical treatment: a retrospective analysis of two randomised radiotherapy trials and one surgical cohort study. Lancet Oncol. 2008;9:342-51.
-
(2008)
Lancet Oncol
, vol.9
, pp. 342-351
-
-
Vergis, R.1
Corbishley, C.M.2
Norman, A.R.3
Bartlett, J.4
Jhavar, S.5
Borre, M.6
Heeboll, S.7
Horwich, A.8
Huddart, R.9
Khoo, V.10
Eeles, R.11
Cooper, C.12
Sydes, M.13
Dearnaley, D.14
Parker, C.15
-
11
-
-
84866927512
-
Coordinated action of hypoxia-inducible factor-1alpha and beta-catenin in androgen receptor signaling
-
Mitani T, Harada N, Nakano Y, Inui H, Yamaji R. Coordinated action of hypoxia-inducible factor-1alpha and beta-catenin in androgen receptor signaling. J Biol Chem. 2012;287:33594-606.
-
(2012)
J Biol Chem
, vol.287
, pp. 33594-33606
-
-
Mitani, T.1
Harada, N.2
Nakano, Y.3
Inui, H.4
Yamaji, R.5
-
12
-
-
84905990584
-
MDM2 regulates hypoxic hypoxia-inducible factor 1alpha stability in an E3 ligase, proteasome, and PTEN-phosphatidylinositol 3-kinase-AKT-dependent manner
-
Joshi S, Singh AR, Durden DL. MDM2 regulates hypoxic hypoxia-inducible factor 1alpha stability in an E3 ligase, proteasome, and PTEN-phosphatidylinositol 3-kinase-AKT-dependent manner. J Biol Chem. 2014;289:22785-97.
-
(2014)
J Biol Chem
, vol.289
, pp. 22785-22797
-
-
Joshi, S.1
Singh, A.R.2
Durden, D.L.3
-
13
-
-
0036789574
-
Regulation of hypoxia-inducible factor 1alpha expression and function by the mammalian target of rapamycin
-
Hudson CC, Liu M, Chiang GG, Otterness DM, Loomis DC, Kaper F, Giaccia AJ, Abraham RT. Regulation of hypoxia-inducible factor 1alpha expression and function by the mammalian target of rapamycin. Mol Cell Biol. 2002;22:7004-14.
-
(2002)
Mol Cell Biol
, vol.22
, pp. 7004-7014
-
-
Hudson, C.C.1
Liu, M.2
Chiang, G.G.3
Otterness, D.M.4
Loomis, D.C.5
Kaper, F.6
Giaccia, A.J.7
Abraham, R.T.8
-
14
-
-
84928923228
-
HIF-1alpha activation by intermittent hypoxia requires NADPH oxidase stimulation by xanthine oxidase
-
Nanduri J, Vaddi DR, Khan SA, Wang N, Makarenko V, Semenza GL, Prabhakar NR. HIF-1alpha activation by intermittent hypoxia requires NADPH oxidase stimulation by xanthine oxidase. PloS One. 2015;10:e0119762.
-
(2015)
Plos One
, vol.10
, pp. 0119762
-
-
Nanduri, J.1
Vaddi, D.R.2
Khan, S.A.3
Wang, N.4
Makarenko, V.5
Semenza, G.L.6
Prabhakar, N.R.7
-
15
-
-
84856103868
-
Lactate is a mediator of metabolic cooperation between stromal carcinoma associated fibroblasts and glycolytic tumor cells in the tumor microenvironment
-
Rattigan YI, Patel BB, Ackerstaff E, Sukenick G, Koutcher JA, Glod JW, Banerjee D. Lactate is a mediator of metabolic cooperation between stromal carcinoma associated fibroblasts and glycolytic tumor cells in the tumor microenvironment. Exp Cell Res. 2012;318:326-35.
-
(2012)
Exp Cell Res
, vol.318
, pp. 326-335
-
-
Rattigan, Y.I.1
Patel, B.B.2
Ackerstaff, E.3
Sukenick, G.4
Koutcher, J.A.5
Glod, J.W.6
Banerjee, D.7
-
16
-
-
84872534173
-
Endothelial cell metabolism and tumour angiogenesis: Glucose and glutamine as essential fuels and lactate as the driving force
-
Polet F, Feron O. Endothelial cell metabolism and tumour angiogenesis: glucose and glutamine as essential fuels and lactate as the driving force. J Internal Med. 2013;273:156-65.
-
(2013)
J Internal Med
, vol.273
, pp. 156-165
-
-
Polet, F.1
Feron, O.2
-
17
-
-
84858120137
-
Targeting the lactate transporter MCT1 in endothelial cells inhibits lactate-induced HIF-1 activation and tumor angiogenesis
-
Sonveaux P, Copetti T, De Saedeleer CJ, Vegran F, Verrax J, Kennedy KM, Moon EJ, Dhup S, Danhier P, Frerart F, Gallez B, Ribeiro A, Michiels C, Dewhirst MW, Feron O. Targeting the lactate transporter MCT1 in endothelial cells inhibits lactate-induced HIF-1 activation and tumor angiogenesis. PloS One. 2012;7:e33418.
-
(2012)
Plos One
, vol.7
, pp. 33418
-
-
Sonveaux, P.1
Copetti, T.2
De Saedeleer, C.J.3
Vegran, F.4
Verrax, J.5
Kennedy, K.M.6
Moon, E.J.7
Dhup, S.8
Danhier, P.9
Frerart, F.10
Gallez, B.11
Ribeiro, A.12
Michiels, C.13
Dewhirst, M.W.14
Feron, O.15
-
18
-
-
84907223092
-
Functional polarization of tumour-associated macrophages by tumour-derived lactic acid
-
Colegio OR, Chu NQ, Szabo AL, Chu T, Rhebergen AM, Jairam V, Cyrus N, Brokowski CE, Eisenbarth SC, Phillips GM, Cline GW, Phillips AJ, Medzhitov R. Functional polarization of tumour-associated macrophages by tumour-derived lactic acid. Nature. 2014;513:559-63.
-
(2014)
Nature
, vol.513
, pp. 559-563
-
-
Colegio, O.R.1
Chu, N.Q.2
Szabo, A.L.3
Chu, T.4
Rhebergen, A.M.5
Jairam, V.6
Cyrus, N.7
Brokowski, C.E.8
Eisenbarth, S.C.9
Phillips, G.M.10
Cline, G.W.11
Phillips, A.J.12
Medzhitov, R.13
-
19
-
-
84890314061
-
The pre-metastatic niche: Finding common ground
-
Sceneay J, Smyth MJ, Moller A. The pre-metastatic niche: finding common ground. Cancer Metast Rev. 2013;32:449-64.
-
(2013)
Cancer Metast Rev
, vol.32
, pp. 449-464
-
-
Sceneay, J.1
Smyth, M.J.2
Moller, A.3
-
20
-
-
84865130953
-
Primary tumor hypoxia recruits CD11b+/Ly6Cmed/Ly6G+ immune suppressor cells and compromises NK cell cytotoxicity in the premetastatic niche
-
Sceneay J, Chow MT, Chen A, Halse HM, Wong CS, Andrews DM, Sloan EK, Parker BS, Bowtell DD, Smyth MJ, Moller A. Primary tumor hypoxia recruits CD11b+/Ly6Cmed/Ly6G+ immune suppressor cells and compromises NK cell cytotoxicity in the premetastatic niche. Cancer Res. 2012;72:3906-11.
-
(2012)
Cancer Res
, vol.72
, pp. 3906-3911
-
-
Sceneay, J.1
Chow, M.T.2
Chen, A.3
Halse, H.M.4
Wong, C.S.5
Rews, D.M.6
Sloan, E.K.7
Parker, B.S.8
Bowtell, D.D.9
Smyth, M.J.10
Moller, A.11
-
21
-
-
85047700200
-
Exosome mediated communication within the tumor microenvironment
-
[Epub ahead of print]. [[AU: PLEASE UPDATE IF POSSIBLE.]]
-
Milane L, Singh A, Mattheolabakis G, Suresh M, Amiji MM. Exosome mediated communication within the tumor microenvironment. J Control Release. 2015 [Epub ahead of print]. [[AU: PLEASE UPDATE IF POSSIBLE.]]
-
(2015)
J Control Release
-
-
Milane, L.1
Singh, A.2
Mattheolabakis, G.3
Suresh, M.4
Amiji, M.M.5
-
22
-
-
84866502787
-
Hypoxic enhancement of exosome release by breast cancer cells
-
King HW, Michael MZ, Gleadle JM. Hypoxic enhancement of exosome release by breast cancer cells. BMC Cancer. 2012;12:421.
-
(2012)
BMC Cancer
, vol.12
, pp. 421
-
-
King, H.W.1
Michael, M.Z.2
Gleadle, J.M.3
-
23
-
-
84941242710
-
Hypoxia induces triglycerides accumulation in prostate cancer cells and extracellular vesicles supporting growth and invasiveness following reoxygenation
-
Schlaepfer IR, Nambiar DK, Ramteke A, Kumar R, Dhar D, Agarwal C, Bergman B, Graner M, Maroni P, Singh RP, Agarwal R, Deep G. Hypoxia induces triglycerides accumulation in prostate cancer cells and extracellular vesicles supporting growth and invasiveness following reoxygenation. Oncotarget. 2015;6:22836-56.
-
(2015)
Oncotarget
, vol.6
, pp. 22836-22856
-
-
Schlaepfer, I.R.1
Nambiar, D.K.2
Ramteke, A.3
Kumar, R.4
Dhar, D.5
Agarwal, C.6
Bergman, B.7
Graner, M.8
Maroni, P.9
Singh, R.P.10
Agarwal, R.11
Deep, G.12
-
24
-
-
84930763705
-
Exosomes secreted under hypoxia enhance invasiveness and stemness of prostate cancer cells by targeting adherens junction molecules
-
Ramteke A, Ting H, Agarwal C, Mateen S, Somasagara R, Hussain A, Graner M, Frederick B, Agarwal R, Deep G. Exosomes secreted under hypoxia enhance invasiveness and stemness of prostate cancer cells by targeting adherens junction molecules. Mol Carcinogen. 2015;54:554-65.
-
(2015)
Mol Carcinogen
, vol.54
, pp. 554-565
-
-
Ramteke, A.1
Ting, H.2
Agarwal, C.3
Mateen, S.4
Somasagara, R.5
Hussain, A.6
Graner, M.7
Frederick, B.8
Agarwal, R.9
Deep, G.10
-
25
-
-
84864131464
-
Adaptive and maladaptive cardiorespiratory responses to continuous and intermittent hypoxia mediated by hypoxia-inducible factors 1 and 2
-
Prabhakar NR, Semenza GL. Adaptive and maladaptive cardiorespiratory responses to continuous and intermittent hypoxia mediated by hypoxia-inducible factors 1 and 2. Physiol Rev. 2012;92:967-1003.
-
(2012)
Physiol Rev
, vol.92
, pp. 967-1003
-
-
Prabhakar, N.R.1
Semenza, G.L.2
-
26
-
-
54049088213
-
Induction of HIF-1alpha expression by intermittent hypoxia: Involvement of NADPH oxidase, Ca2+ signaling, prolyl hydroxylases, and mTOR
-
Yuan G, Nanduri J, Khan S, Semenza GL, Prabhakar NR. Induction of HIF-1alpha expression by intermittent hypoxia: involvement of NADPH oxidase, Ca2+ signaling, prolyl hydroxylases, and mTOR. Journal of Cellular Physiology. 2008;217:674-85.
-
(2008)
Journal of Cellular Physiology
, vol.217
, pp. 674-685
-
-
Yuan, G.1
Nanduri, J.2
Khan, S.3
Semenza, G.L.4
Prabhakar, N.R.5
-
27
-
-
0036216692
-
HIF-1 and tumor progression: Pathophysiology and therapeutics
-
Semenza GL. HIF-1 and tumor progression: pathophysiology and therapeutics. Trends Mol Med. 2002;8:S62-7.
-
(2002)
Trends Mol Med
, vol.8
, pp. S62-S67
-
-
Semenza, G.L.1
-
28
-
-
33745303045
-
Hypoxia signalling in cancer and approaches to enforce tumour regression
-
Pouyssegur J, Dayan F, Mazure NM. Hypoxia signalling in cancer and approaches to enforce tumour regression. Nature. 2006;441:437-43.
-
(2006)
Nature
, vol.441
, pp. 437-443
-
-
Pouyssegur, J.1
Dayan, F.2
Mazure, N.M.3
-
29
-
-
4143110440
-
HIF-1: Master and commander of the hypoxic world. A pharmacological approach to its regulation by siRNAs
-
Mazure NM, Brahimi-Horn MC, Berta MA, Benizri E, Bilton RL, Dayan F, Ginouves A, Berra E, Pouyssegur J. HIF-1: master and commander of the hypoxic world. A pharmacological approach to its regulation by siRNAs. Biochem Pharmacol. 2004;68:971-80.
-
(2004)
Biochem Pharmacol
, vol.68
, pp. 971-980
-
-
Mazure, N.M.1
Brahimi-Horn, M.C.2
Berta, M.A.3
Benizri, E.4
Bilton, R.L.5
Dayan, F.6
Ginouves, A.7
Berra, E.8
Pouyssegur, J.9
-
30
-
-
84904202650
-
Overexpression of hypoxia-inducible factor-1alpha is a predictor of poor prognosis in cervical cancer: A clinicopathologic study and a meta-analysis
-
Huang M, Chen Q, Xiao J, Yao T, Bian L, Liu C, Lin Z. Overexpression of hypoxia-inducible factor-1alpha is a predictor of poor prognosis in cervical cancer: a clinicopathologic study and a meta-analysis. Int J Gynecol Cancer. 2014;24:1054-64.
-
(2014)
Int J Gynecol Cancer
, vol.24
, pp. 1054-1064
-
-
Huang, M.1
Chen, Q.2
Xiao, J.3
Yao, T.4
Bian, L.5
Liu, C.6
Lin, Z.7
-
31
-
-
84897380818
-
Prognosis value of HIF-1alpha expression in patients with non-small cell lung cancer
-
Wang Q, Hu DF, Rui Y, Jiang AB, Liu ZL, Huang LN. Prognosis value of HIF-1alpha expression in patients with non-small cell lung cancer. Gene. 2014;541:69-74.
-
(2014)
Gene
, vol.541
, pp. 69-74
-
-
Wang, Q.1
Hu, D.F.2
Rui, Y.3
Jiang, A.B.4
Liu, Z.L.5
Huang, L.N.6
-
32
-
-
84891918539
-
Prognostic value and clinicopathological differences of HIFs in colorectal cancer: Evidence from meta-analysis
-
Chen Z, He X, Xia W, Huang Q, Zhang Z, Ye J, Ni C, Wu P, Wu D, Xu J, Qiu F, Huang J. Prognostic value and clinicopathological differences of HIFs in colorectal cancer: evidence from meta-analysis. PloS One. 2013;8:e80337.
-
(2013)
Plos One
, vol.8
, pp. 80337
-
-
Chen, Z.1
He, X.2
Xia, W.3
Huang, Q.4
Zhang, Z.5
Ye, J.6
Ni, C.7
Wu, P.8
Wu, D.9
Xu, J.10
Qiu, F.11
Huang, J.12
-
33
-
-
84859445000
-
Hypoxia-inducible factors: Mediators of cancer progression and targets for cancer therapy
-
Semenza GL. Hypoxia-inducible factors: mediators of cancer progression and targets for cancer therapy. Trends Pharmacol Sci. 2012;33:207-14.
-
(2012)
Trends Pharmacol Sci
, vol.33
, pp. 207-214
-
-
Semenza, G.L.1
-
34
-
-
0142166332
-
Targeting HIF-1 for cancer therapy
-
Semenza GL. Targeting HIF-1 for cancer therapy. Nat Rev Cancer. 2003;3:721-732.
-
(2003)
Nat Rev Cancer
, vol.3
, pp. 721-732
-
-
Semenza, G.L.1
-
35
-
-
84872340716
-
The critical impact of HIF-1a on gastric cancer biology
-
Kitajima Y, Miyazaki K. The critical impact of HIF-1a on gastric cancer biology. Cancers. 2013;5:1 5-26.
-
(2013)
Cancers
, vol.5
, Issue.1
, pp. 5-26
-
-
Kitajima, Y.1
Miyazaki, K.2
-
36
-
-
78650373860
-
Hypoxia and hypoxia-inducible factors: Master regulators of metastasis
-
Lu X, Kang Y. Hypoxia and hypoxia-inducible factors: master regulators of metastasis. Clin Cancer Res. 2010;16:5928-5935.
-
(2010)
Clin Cancer Res
, vol.16
, pp. 5928-5935
-
-
Lu, X.1
Kang, Y.2
-
37
-
-
0037220316
-
Acute hypoxia increases the aggressive characteristics and survival properties of prostate cancer cells
-
Ghafar MA, Anastasiadis AG, Chen MW, Burchardt M, Olsson LE, Xie H, Benson MC, Buttyan R. Acute hypoxia increases the aggressive characteristics and survival properties of prostate cancer cells. Prostate. 2003;54:58-67.
-
(2003)
Prostate
, vol.54
, pp. 58-67
-
-
Ghafar, M.A.1
Anastasiadis, A.G.2
Chen, M.W.3
Burchardt, M.4
Olsson, L.E.5
Xie, H.6
Benson, M.C.7
Buttyan, R.8
-
38
-
-
36148988817
-
HIF-1 and NF-kappaB-mediated upregulation of CXCR1 and CXCR2 expression promotes cell survival in hypoxic prostate cancer cells
-
Maxwell PJ, Gallagher R, Seaton A, Wilson C, Scullin P, Pettigrew J, Stratford IJ, Williams KJ, Johnston PG, Waugh DJ. HIF-1 and NF-kappaB-mediated upregulation of CXCR1 and CXCR2 expression promotes cell survival in hypoxic prostate cancer cells. Oncogene. 2007;26:7333-45.
-
(2007)
Oncogene
, vol.26
, pp. 7333-7345
-
-
Maxwell, P.J.1
Gallagher, R.2
Seaton, A.3
Wilson, C.4
Scullin, P.5
Pettigrew, J.6
Stratford, I.J.7
Williams, K.J.8
Johnston, P.G.9
Waugh, D.J.10
-
39
-
-
39149100964
-
Hypoxia regulates choline kinase expression through hypoxia-inducible factor-1 alpha signaling in a human prostate cancer model
-
Glunde K, Shah T, Winnard PT, Jr., Raman V, Takagi T, Vesuna F, Artemov D, Bhujwalla ZM. Hypoxia regulates choline kinase expression through hypoxia-inducible factor-1 alpha signaling in a human prostate cancer model. Cancer Res. 2008;68:172-80.
-
(2008)
Cancer Res
, vol.68
, pp. 172-180
-
-
Glunde, K.1
Shah, T.2
Winnard, P.T.3
Raman, V.4
Takagi, T.5
Vesuna, F.6
Artemov, D.7
Bhujwalla, Z.M.8
-
40
-
-
34248169327
-
Androgen-dependent gene expression of prostate-specific antigen is enhanced synergistically by hypoxia in human prostate cancer cells
-
Horii K, Suzuki Y, Kondo Y, Akimoto M, Nishimura T, Yamabe Y, Sakaue M, Sano T, Kitagawa T, Himeno S, Imura N, Hara S. Androgen-dependent gene expression of prostate-specific antigen is enhanced synergistically by hypoxia in human prostate cancer cells. Mol Cancer Research. 2007;5:383-91.
-
(2007)
Mol Cancer Research
, vol.5
, pp. 383-391
-
-
Horii, K.1
Suzuki, Y.2
Kondo, Y.3
Akimoto, M.4
Nishimura, T.5
Yamabe, Y.6
Sakaue, M.7
Sano, T.8
Kitagawa, T.9
Himeno, S.10
Imura, N.11
Hara, S.12
-
41
-
-
78650572564
-
Hypoxia enhances transcriptional activity of androgen receptor through hypoxia-inducible factor-1alpha in a low androgen environment
-
Mitani T, Yamaji R, Higashimura Y, Harada N, Nakano Y, Inui H. Hypoxia enhances transcriptional activity of androgen receptor through hypoxia-inducible factor-1alpha in a low androgen environment. J Steroid Biochem Mol Biol. 2011;123:58-64.
-
(2011)
J Steroid Biochem Mol Biol
, vol.123
, pp. 58-64
-
-
Mitani, T.1
Yamaji, R.2
Higashimura, Y.3
Harada, N.4
Nakano, Y.5
Inui, H.6
-
42
-
-
84884672514
-
Exposure to hypoxia following irradiation increases radioresistance in prostate cancer cells
-
Hennessey D, Martin LM, Atzberger A, Lynch TH, Hollywood D, Marignol L. Exposure to hypoxia following irradiation increases radioresistance in prostate cancer cells. Urol Oncol. 2013;31:1106-6.
-
(2013)
Urol Oncol
, vol.31
, pp. 1106-1116
-
-
Hennessey, D.1
Martin, L.M.2
Atzberger, A.3
Lynch, T.H.4
Hollywood, D.5
Marignol, L.6
-
43
-
-
84555203275
-
Prostate cancer cell lines under hypoxia exhibit greater stem-like properties
-
Ma Y, Liang D, Liu J, Axcrona K, Kvalheim G, Stokke T, Nesland JM, Suo Z. Prostate cancer cell lines under hypoxia exhibit greater stem-like properties. PloS One. 2011;6:e29170.
-
(2011)
Plos One
, vol.6
, pp. 29170
-
-
Ma, Y.1
Liang, D.2
Liu, J.3
Axcrona, K.4
Kvalheim, G.5
Stokke, T.6
Nesland, J.M.7
Suo, Z.8
-
44
-
-
84867842267
-
Hypoxia and HIF-1 increase S100A8 and S100A9 expression in prostate cancer
-
Grebhardt S, Veltkamp C, Strobel P, Mayer D. Hypoxia and HIF-1 increase S100A8 and S100A9 expression in prostate cancer. Int J Cancer. 2012;131:2785-94.
-
(2012)
Int J Cancer
, vol.131
, pp. 2785-2794
-
-
Grebhardt, S.1
Veltkamp, C.2
Strobel, P.3
Mayer, D.4
-
45
-
-
84867811185
-
Hypoxia increases CX3CR1 expression via HIF-1 and NFkappaB in androgen-independent prostate cancer cells
-
Xiao LJ, Chen YY, Lin P, Zou HF, Lin F, Zhao LN, Li D, Guo L, Tang JB, Zheng XL, Yu XG. Hypoxia increases CX3CR1 expression via HIF-1 and NFkappaB in androgen-independent prostate cancer cells. Int Jgy. 2012;41:1827-36.
-
(2012)
Int Jgy
, vol.41
, pp. 1827-1836
-
-
Xiao, L.J.1
Chen, Y.Y.2
Lin, P.3
Zou, H.F.4
Lin, F.5
Zhao, L.N.6
Li, D.7
Guo, L.8
Tang, J.B.9
Zheng, X.L.10
Yu, X.G.11
-
46
-
-
84903397987
-
Stabilization of Snail by HIF-1alpha and TNF-alpha is required for hypoxia-induced invasion in prostate cancer PC3 cells
-
Lv L, Yuan J, Huang T, Zhang C, Zhu Z, Wang L, Jiang G, Zeng F. Stabilization of Snail by HIF-1alpha and TNF-alpha is required for hypoxia-induced invasion in prostate cancer PC3 cells. Mol Biol Rep. 2014;41:4573-82.
-
(2014)
Mol Biol Rep
, vol.41
, pp. 4573-4582
-
-
Lv, L.1
Yuan, J.2
Huang, T.3
Zhang, C.4
Zhu, Z.5
Wang, L.6
Jiang, G.7
Zeng, F.8
-
47
-
-
0035866779
-
Angiogenesis and prostate cancer: Identification of a molecular progression switch
-
Huss WJ, Hanrahan CF, Barrios RJ, Simons JW, Greenberg NM. Angiogenesis and prostate cancer: identification of a molecular progression switch. Cancer Res. 2001;61:2736-43.
-
(2001)
Cancer Res
, vol.61
, pp. 2736-2743
-
-
Huss, W.J.1
Hanrahan, C.F.2
Barrios, R.J.3
Simons, J.W.4
Greenberg, N.M.5
-
48
-
-
53049106036
-
Stage-specific inhibitory effects and associated mechanisms of silibinin on tumor progression and metastasis in transgenic adenocarcinoma of the mouse prostate model
-
Raina K, Rajamanickam S, Singh RP, Deep G, Chittezhath M, Agarwal R. Stage-specific inhibitory effects and associated mechanisms of silibinin on tumor progression and metastasis in transgenic adenocarcinoma of the mouse prostate model. Cancer Res. 2008;68:6822-30.
-
(2008)
Cancer Res
, vol.68
, pp. 6822-6830
-
-
Raina, K.1
Rajamanickam, S.2
Singh, R.P.3
Deep, G.4
Chittezhath, M.5
Agarwal, R.6
-
49
-
-
84858079914
-
PI3K/AKT/mTOR Pathway in Angiogenesis
-
Karar J, Maity A. PI3K/AKT/mTOR Pathway in Angiogenesis. Front Mol Neuroscie. 2011;4:51.
-
(2011)
Front Mol Neuroscie
, vol.4
, pp. 51
-
-
Karar, J.1
Maity, A.2
-
50
-
-
28844448182
-
Oncogenic PI3K deregulates transcription and translation
-
Bader AG, Kang S, Zhao L, Vogt PK. Oncogenic PI3K deregulates transcription and translation. Nat Rev Cancer. 2005;5:921-9.
-
(2005)
Nat Rev Cancer
, vol.5
, pp. 921-929
-
-
Bader, A.G.1
Kang, S.2
Zhao, L.3
Vogt, P.K.4
-
51
-
-
84900471149
-
PI3K-AKT-mTOR signaling in prostate cancer progression and androgen deprivation therapy resistance
-
Edlind MP, Hsieh AC. PI3K-AKT-mTOR signaling in prostate cancer progression and androgen deprivation therapy resistance. Asian J Androl. 2014;16:378-86.
-
(2014)
Asian J Androl
, vol.16
, pp. 378-386
-
-
Edlind, M.P.1
Hsieh, A.C.2
-
52
-
-
0030992837
-
Signalling through the lipid products of phosphoinositide-3-OH kinase
-
Toker A, Cantley LC. Signalling through the lipid products of phosphoinositide-3-OH kinase. Nature. 1997;387:673-6.
-
(1997)
Nature
, vol.387
, pp. 673-676
-
-
Toker, A.1
Cantley, L.C.2
-
53
-
-
84884673461
-
Chronic hypoxia induces androgen-independent and invasive behavior in LNCaP human prostate cancer cells
-
Yamasaki M, Nomura T, Sato F, Mimata H. Chronic hypoxia induces androgen-independent and invasive behavior in LNCaP human prostate cancer cells. Urol Oncol. 2013;31:1124-31.
-
(2013)
Urol Oncol
, vol.31
, pp. 1124-1131
-
-
Yamasaki, M.1
Nomura, T.2
Sato, F.3
Mimata, H.4
-
54
-
-
0035477438
-
Effects of ras and von Hippel-Lindau (VHL) gene mutations on hypoxia-inducible factor (HIF)-1alpha, HIF-2alpha, and vascular endothelial growth factor expression and their regulation by the phosphatidylinositol 3’-kinase/Akt signaling pathway
-
Blancher C, Moore JW, Robertson N, Harris AL. Effects of ras and von Hippel-Lindau (VHL) gene mutations on hypoxia-inducible factor (HIF)-1alpha, HIF-2alpha, and vascular endothelial growth factor expression and their regulation by the phosphatidylinositol 3’-kinase/Akt signaling pathway. Cancer Res. 2001;61:7349-55.
-
(2001)
Cancer Res
, vol.61
, pp. 7349-7355
-
-
Blancher, C.1
Moore, J.W.2
Robertson, N.3
Harris, A.L.4
-
55
-
-
64049102268
-
PI3 kinase/Akt signaling mediates epithelial-mesenchymal transition in hypoxic hepatocellular carcinoma cells
-
Yan W, Fu Y, Tian D, Liao J, Liu M, Wang B, Xia L, Zhu Q, Luo M. PI3 kinase/Akt signaling mediates epithelial-mesenchymal transition in hypoxic hepatocellular carcinoma cells. Biochem Biophys Res Commun. 2009;382:631-6.
-
(2009)
Biochem Biophys Res Commun
, vol.382
, pp. 631-636
-
-
Yan, W.1
Fu, Y.2
Tian, D.3
Liao, J.4
Liu, M.5
Wang, B.6
Xia, L.7
Zhu, Q.8
Luo, M.9
-
56
-
-
84857368471
-
Bortezomib represses HIF-1alpha protein expression and nuclear accumulation by inhibiting both PI3K/Akt/TOR and MAPK pathways in prostate cancer cells
-
Befani CD, Vlachostergios PJ, Hatzidaki E, Patrikidou A, Bonanou S, Simos G, Papandreou CN, Liakos P. Bortezomib represses HIF-1alpha protein expression and nuclear accumulation by inhibiting both PI3K/Akt/TOR and MAPK pathways in prostate cancer cells. J Mol Med (Berl). 2012;90:45-54.
-
(2012)
J Mol Med (Berl)
, vol.90
, pp. 45-54
-
-
Befani, C.D.1
Vlachostergios, P.J.2
Hatzidaki, E.3
Patrikidou, A.4
Bonanou, S.5
Simos, G.6
Papandreou, C.N.7
Liakos, P.8
-
57
-
-
84906937492
-
Gambogic acid suppresses hypoxia-induced hypoxia-inducible factor-1alpha/vascular endothelial growth factor expression via inhibiting phosphatidylinositol 3-kinase/Akt/mammalian target protein of rapamycin pathway in multiple myeloma cells
-
Wang F, Zhang W, Guo L, Bao W, Jin N, Liu R, Liu P, Wang Y, Guo Q, Chen B. Gambogic acid suppresses hypoxia-induced hypoxia-inducible factor-1alpha/vascular endothelial growth factor expression via inhibiting phosphatidylinositol 3-kinase/Akt/mammalian target protein of rapamycin pathway in multiple myeloma cells. Cancer Sci. 2014;105:1063-70.
-
(2014)
Cancer Sci
, vol.105
, pp. 1063-1070
-
-
Wang, F.1
Zhang, W.2
Guo, L.3
Bao, W.4
Jin, N.5
Liu, R.6
Liu, P.7
Wang, Y.8
Guo, Q.9
Chen, B.10
-
58
-
-
84919753042
-
A group of novel HIF-1alpha inhibitors, glyceollins, blocks HIF-1alpha synthesis and decreases its stability via inhibition of the PI3K/AKT/mTOR pathway and Hsp90 binding
-
Lee SH, Jee JG, Bae JS, Liu KH, Lee YM. A group of novel HIF-1alpha inhibitors, glyceollins, blocks HIF-1alpha synthesis and decreases its stability via inhibition of the PI3K/AKT/mTOR pathway and Hsp90 binding. J Cell Physiol. 2015;230:853-62.
-
(2015)
J Cell Physiol
, vol.230
, pp. 853-862
-
-
Lee, S.H.1
Jee, J.G.2
Bae, J.S.3
Liu, K.H.4
Lee, Y.M.5
-
59
-
-
84938269468
-
Low molecular weight fucoidan inhibits tumor angiogenesis through downregulation of HIF-1/VEGF signaling under hypoxia
-
Chen MC, Hsu WL, Hwang PA, Chou TC. Low molecular weight fucoidan inhibits tumor angiogenesis through downregulation of HIF-1/VEGF signaling under hypoxia. Marine Drugs. 2015;13:4436-51.
-
(2015)
Marine Drugs
, vol.13
, pp. 4436-4451
-
-
Chen, M.C.1
Hsu, W.L.2
Hwang, P.A.3
Chou, T.C.4
-
60
-
-
79961104134
-
A novel inhibitor of hypoxia-inducible factor-1alpha P3155 also modulates PI3K pathway and inhibits growth of prostate cancer cells
-
Manohar SM, Padgaonkar AA, Jalota-Badhwar A, Sonawane V, Rathos MJ, Kumar S, Joshi KS. A novel inhibitor of hypoxia-inducible factor-1alpha P3155 also modulates PI3K pathway and inhibits growth of prostate cancer cells. BMC Cancer. 2011;11:338.
-
(2011)
BMC Cancer
, vol.11
, pp. 338
-
-
Manohar, S.M.1
Padgaonkar, A.A.2
Jalota-Badhwar, A.3
Sonawane, V.4
Rathos, M.J.5
Kumar, S.6
Joshi, K.S.7
-
61
-
-
84924311131
-
Regulation of hypoxia-inducible factor-1a by reactive oxygen species: New developments in an old debate
-
Movafagh S, Crook S, Vo K. Regulation of hypoxia-inducible factor-1a by reactive oxygen species: new developments in an old debate. J Cell Biochem. 2015;116:696-703.
-
(2015)
J Cell Biochem
, vol.116
, pp. 696-703
-
-
Movafagh, S.1
Crook, S.2
Vo, K.3
-
62
-
-
84920122203
-
The unfolded protein response potentiates epithelial-to-mesenchymal transition (EMT) of gastric cancer cells under severe hypoxic conditions
-
Shen X, Xue Y, Si Y, Wang Q, Wang Z, Yuan J, Zhang X. The unfolded protein response potentiates epithelial-to-mesenchymal transition (EMT) of gastric cancer cells under severe hypoxic conditions. Med Oncol. 2015;32:447.
-
(2015)
Med Oncol
, vol.32
, pp. 447
-
-
Shen, X.1
Xue, Y.2
Si, Y.3
Wang, Q.4
Wang, Z.5
Yuan, J.6
Zhang, X.7
-
63
-
-
54249088951
-
Sphingosine kinase 1: A new modulator of hypoxia inducible factor 1alpha during hypoxia in human cancer cells
-
Ader I, Brizuela L, Bouquerel P, Malavaud B, Cuvillier O. Sphingosine kinase 1: a new modulator of hypoxia inducible factor 1alpha during hypoxia in human cancer cells. Cancer Research. 2008;68:8635-42.
-
(2008)
Cancer Research
, vol.68
, pp. 8635-8642
-
-
Ader, I.1
Brizuela, L.2
Bouquerel, P.3
Malavaud, B.4
Cuvillier, O.5
-
64
-
-
67650173313
-
Oxidative stress in prostate cancer
-
Khandrika L, Kumar B, Koul S, Maroni P, Koul HK. Oxidative stress in prostate cancer. Cancer Lett. 2009;282:125-36.
-
(2009)
Cancer Lett
, vol.282
, pp. 125-136
-
-
Khandrika, L.1
Kumar, B.2
Koul, S.3
Maroni, P.4
Koul, H.K.5
-
65
-
-
40949159866
-
Oxidative stress is inherent in prostate cancer cells and is required for aggressive phenotype
-
Kumar B, Koul S, Khandrika L, Meacham RB, Koul HK. Oxidative stress is inherent in prostate cancer cells and is required for aggressive phenotype. Cancer Res. 2008;68:1777-85.
-
(2008)
Cancer Res
, vol.68
, pp. 1777-1785
-
-
Kumar, B.1
Koul, S.2
Khandrika, L.3
Meacham, R.B.4
Koul, H.K.5
-
66
-
-
11844272091
-
Increased Nox1 and hydrogen peroxide in prostate cancer
-
Lim SD, Sun C, Lambeth JD, Marshall F, Amin M, Chung L, Petros JA, Arnold RS. Increased Nox1 and hydrogen peroxide in prostate cancer. Prostate. 2005;62:200-7.
-
(2005)
Prostate
, vol.62
, pp. 200-207
-
-
Lim, S.D.1
Sun, C.2
Lambeth, J.D.3
Marshall, F.4
Amin, M.5
Chung, L.6
Petros, J.A.7
Arnold, R.S.8
-
67
-
-
84886843534
-
NADPH oxidase subunit p22(Phox)-mediated reactive oxygen species contribute to angiogenesis and tumor growth through AKT and ERK1/2 signaling pathways in prostate cancer
-
Li Q, Fu GB, Zheng JT, He J, Niu XB, Chen QD, Yin Y, Qian X, Xu Q, Wang M, Sun AF, Shu Y, Rui H, Liu LZ, Jiang BH. NADPH oxidase subunit p22(phox)-mediated reactive oxygen species contribute to angiogenesis and tumor growth through AKT and ERK1/2 signaling pathways in prostate cancer. Biochim Biophys Acta. 2013;1833:3375-85.
-
(2013)
Biochim Biophys Acta
, vol.1833
, pp. 3375-3385
-
-
Li, Q.1
Fu, G.B.2
Zheng, J.T.3
He, J.4
Niu, X.B.5
Chen, Q.D.6
Yin, Y.7
Qian, X.8
Xu, Q.9
Wang, M.10
Sun, A.F.11
Shu, Y.12
Rui, H.13
Liu, L.Z.14
Jiang, B.H.15
-
68
-
-
34347257042
-
Nox enzymes, ROS, and chronic disease: An example of antagonistic pleiotropy
-
Lambeth JD. Nox enzymes, ROS, and chronic disease: an example of antagonistic pleiotropy. Free Radical Biol Med. 2007;43:332-47.
-
(2007)
Free Radical Biol Med
, vol.43
, pp. 332-347
-
-
Lambeth, J.D.1
-
69
-
-
67650657198
-
Roles of Nox1 and other Nox isoforms in cancer development
-
Kamata T. Roles of Nox1 and other Nox isoforms in cancer development. Cancer Sci. 2009;100:1382-8.
-
(2009)
Cancer Sci
, vol.100
, pp. 1382-1388
-
-
6Kamata, T.1
-
70
-
-
84866425239
-
Aiding and abetting roles of NOX oxidases in cellular transformation
-
Block K, Gorin Y. Aiding and abetting roles of NOX oxidases in cellular transformation. Nat Rev Cancer. 2012;12:627-37.
-
(2012)
Nat Rev Cancer
, vol.12
, pp. 627-637
-
-
Block, K.1
Gorin, Y.2
-
71
-
-
0033517275
-
Cell transformation by the superoxide-generating oxidase Mox1
-
Suh YA, Arnold RS, Lassegue B, Shi J, Xu X, Sorescu D, Chung AB, Griendling KK, Lambeth JD. Cell transformation by the superoxide-generating oxidase Mox1. Nature. 1999;401:79-82.
-
(1999)
Nature
, vol.401
, pp. 79-82
-
-
Suh, Y.A.1
Arnold, R.S.2
Lassegue, B.3
Shi, J.4
Xu, X.5
Sorescu, D.6
Chung, A.B.7
Griendling, K.K.8
Lambeth, J.D.9
-
72
-
-
79961135075
-
Cisplatin induces production of reactive oxygen species via NADPH oxidase activation in human prostate cancer cells
-
Itoh T, Terazawa R, Kojima K, Nakane K, Deguchi T, Ando M, Tsukamasa Y, Ito M, Nozawa Y. Cisplatin induces production of reactive oxygen species via NADPH oxidase activation in human prostate cancer cells. Free Radical Res. 2011;45:1033-9.
-
(2011)
Free Radical Res
, vol.45
, pp. 1033-1039
-
-
Itoh, T.1
Terazawa, R.2
Kojima, K.3
Nakane, K.4
Deguchi, T.5
Ando, M.6
Tsukamasa, Y.7
Ito, M.8
Nozawa, Y.9
-
73
-
-
0037154250
-
Reactive oxygen generated by Nox1 triggers the angiogenic switch
-
Arbiser JL, Petros J, Klafter R, Govindajaran B, McLaughlin ER, Brown LF, Cohen C, Moses M, Kilroy S, Arnold RS, Lambeth JD. Reactive oxygen generated by Nox1 triggers the angiogenic switch. Proc Natl Acad Sci U S A. 2002;99:715-20.
-
(2002)
Proc Natl Acad Sci U S A
, vol.99
, pp. 715-720
-
-
Arbiser, J.L.1
Petros, J.2
Klafter, R.3
Govindajaran, B.4
McLaughlin, E.R.5
Brown, L.F.6
Cohen, C.7
Moses, M.8
Kilroy, S.9
Arnold, R.S.10
Lambeth, J.D.11
-
74
-
-
0042242883
-
NOX5 NAD(P)H oxidase regulates growth and apoptosis in DU 145 prostate cancer cells
-
Brar SS, Corbin Z, Kennedy TP, Hemendinger R, Thornton L, Bommarius B, Arnold RS, Whorton AR, Sturrock AB, Huecksteadt TP, Quinn MT, Krenitsky K, Ardie KG, Lambeth JD, Hoidal JR. NOX5 NAD(P)H oxidase regulates growth and apoptosis in DU 145 prostate cancer cells. Am J Physiol Cell Physiol. 2003;285:C353-69.
-
(2003)
Am J Physiol Cell Physiol
, vol.285
, pp. C353-C369
-
-
Brar, S.S.1
Corbin, Z.2
Kennedy, T.P.3
Hemendinger, R.4
Thornton, L.5
Bommarius, B.6
Arnold, R.S.7
Whorton, A.R.8
Sturrock, A.B.9
Huecksteadt, T.P.10
Quinn, M.T.11
Krenitsky, K.12
Ardie, K.G.13
Lambeth, J.D.14
Hoidal, J.R.15
-
75
-
-
79960697192
-
Hypoxia-inducible factor 1 mediates increased expression of NADPH oxidase-2 in response to intermittent hypoxia
-
Yuan G, Khan SA, Luo W, Nanduri J, Semenza GL, Prabhakar NR. Hypoxia-inducible factor 1 mediates increased expression of NADPH oxidase-2 in response to intermittent hypoxia. J Cell Physiol. 2011;226:2925-33.
-
(2011)
J Cell Physiol
, vol.226
, pp. 2925-2933
-
-
Yuan, G.1
Khan, S.A.2
Luo, W.3
Nanduri, J.4
Semenza, G.L.5
Prabhakar, N.R.6
-
76
-
-
77953518507
-
The NADPH oxidase subunit NOX4 is a new target gene of the hypoxia-inducible factor-1
-
Diebold I, Petry A, Hess J, Gorlach A. The NADPH oxidase subunit NOX4 is a new target gene of the hypoxia-inducible factor-1. MoleBiol Cell. 2010;21:2087-96.
-
(2010)
Molebiol Cell
, vol.21
, pp. 2087-2096
-
-
Diebold, I.1
Petry, A.2
Hess, J.3
Gorlach, A.4
-
77
-
-
84864404681
-
NADPH oxidase subunit 4 mediates cycling hypoxia-promoted radiation resistance in glioblastoma multiforme
-
Hsieh CH, Wu CP, Lee HT, Liang JA, Yu CY, Lin YJ. NADPH oxidase subunit 4 mediates cycling hypoxia-promoted radiation resistance in glioblastoma multiforme. Free Radical Biol Med. 2012;53:649-58.
-
(2012)
Free Radical Biol Med
, vol.53
, pp. 649-658
-
-
Hsieh, C.H.1
Wu, C.P.2
Lee, H.T.3
Liang, J.A.4
Yu, C.Y.5
Lin, Y.J.6
-
78
-
-
34247250752
-
NAD(P)H oxidases regulate HIF-2alpha protein expression
-
Block K, Gorin Y, Hoover P, Williams P, Chelmicki T, Clark RA, Yoneda T, Abboud HE. NAD(P)H oxidases regulate HIF-2alpha protein expression. J Biol Chem. 2007;282:8019-26.
-
(2007)
J Biol Chem
, vol.282
, pp. 8019-8026
-
-
Block, K.1
Gorin, Y.2
Hoover, P.3
Williams, P.4
Chelmicki, T.5
Clark, R.A.6
Yoneda, T.7
Abboud, H.E.8
-
79
-
-
78650580513
-
NADPH oxidase-mediated reactive oxygen species production activates hypoxia-inducible factor-1 (HIF-1) via the ERK pathway after hyperthermia treatment
-
Moon EJ, Sonveaux P, Porporato PE, Danhier P, Gallez B, Batinic-Haberle I, Nien YC, Schroeder T, Dewhirst MW. NADPH oxidase-mediated reactive oxygen species production activates hypoxia-inducible factor-1 (HIF-1) via the ERK pathway after hyperthermia treatment. Proc Natl Acad Sci U S A. 2010;107:20477-82.
-
(2010)
Proc Natl Acad Sci U S A
, vol.107
, pp. 20477-20482
-
-
Moon, E.J.1
Sonveaux, P.2
Porporato, P.E.3
Danhier, P.4
Gallez, B.5
Batinic-Haberle, I.6
Nien, Y.C.7
Schroeder, T.8
Dewhirst, M.W.9
-
80
-
-
4344584730
-
WNT and beta-catenin signalling: Diseases and therapies. Nature reviews
-
Moon RT, Kohn AD, De Ferrari GV, Kaykas A. WNT and beta-catenin signalling: diseases and therapies. Nature reviews. Genetics. 2004;5:691-701.
-
(2004)
Genetics
, vol.5
, pp. 691-701
-
-
Moon, R.T.1
Kohn, A.D.2
De Ferrari, G.V.3
Kaykas, A.4
-
81
-
-
84908573021
-
Down regulation of Wnt signaling mitigates hypoxia-induced chemoresistance in human osteosarcoma cells
-
Scholten DJ, 2nd, Timmer CM, Peacock JD, Pelle DW, Williams BO, Steensma MR. Down regulation of Wnt signaling mitigates hypoxia-induced chemoresistance in human osteosarcoma cells. PloS One. 2014;9:e111431.
-
(2014)
Plos One
, vol.9
, pp. 111431
-
-
Scholten, D.J.1
Timmer, C.M.2
Peacock, J.D.3
Pelle, D.W.4
Williams, B.O.5
Steensma, M.R.6
-
82
-
-
84911880059
-
Hypoxia-inducible factors modulate the stemness and malignancy of colon cancer cells by playing opposite roles in canonical Wnt signaling
-
Santoyo-Ramos P, Likhatcheva M, Garcia-Zepeda EA, Castaneda-Patlan MC, Robles-Flores M. Hypoxia-inducible factors modulate the stemness and malignancy of colon cancer cells by playing opposite roles in canonical Wnt signaling. PloS One. 2014;9:e112580.
-
(2014)
Plos One
, vol.9
, pp. 112580
-
-
Santoyo-Ramos, P.1
Likhatcheva, M.2
Garcia-Zepeda, E.A.3
Castaneda-Patlan, M.C.4
Robles-Flores, M.5
-
83
-
-
79958201891
-
Knockdown of beta-Catenin through shRNA cause a reversal of EMT and metastatic phenotypes induced by HIF-1alpha
-
Zhao JH, Luo Y, Jiang YG, He DL, Wu CT. Knockdown of beta-Catenin through shRNA cause a reversal of EMT and metastatic phenotypes induced by HIF-1alpha. Cancer Invest. 2011;29:377-82.
-
(2011)
Cancer Invest
, vol.29
, pp. 377-382
-
-
Zhao, J.H.1
Luo, Y.2
Jiang, Y.G.3
He, D.L.4
Wu, C.T.5
-
84
-
-
77952324704
-
Activation of beta-catenin by hypoxia in hepatocellular carcinoma contributes to enhanced metastatic potential and poor prognosis
-
Liu L, Zhu XD, Wang WQ, Shen Y, Qin Y, Ren ZG, Sun HC, Tang ZY. Activation of beta-catenin by hypoxia in hepatocellular carcinoma contributes to enhanced metastatic potential and poor prognosis. Clin Cancer Res. 2010;16:2740-50.
-
(2010)
Clin Cancer Res
, vol.16
, pp. 2740-2750
-
-
Liu, L.1
Zhu, X.D.2
Wang, W.Q.3
Shen, Y.4
Qin, Y.5
Ren, Z.G.6
Sun, H.C.7
Tang, Z.Y.8
-
85
-
-
34247583794
-
Glycogen synthase kinase 3 phosphorylates hypoxia-inducible factor 1alpha and mediates its destabilization in a VHL-independent manner
-
Flugel D, Gorlach A, Michiels C, Kietzmann T. Glycogen synthase kinase 3 phosphorylates hypoxia-inducible factor 1alpha and mediates its destabilization in a VHL-independent manner. Mol Cell Biol. 2007;27:3253-65.
-
(2007)
Mol Cell Biol
, vol.27
, pp. 3253-3265
-
-
Flugel, D.1
Gorlach, A.2
Michiels, C.3
Kietzmann, T.4
-
86
-
-
11844263980
-
Inhibition of GSK3beta by indirubins restores HIF-1alpha accumulation under prolonged periods of hypoxia/ anoxia
-
Schnitzer SE, Schmid T, Zhou J, Eisenbrand G, Brune B. Inhibition of GSK3beta by indirubins restores HIF-1alpha accumulation under prolonged periods of hypoxia/ anoxia. FEBS Lett. 2005;579:529-33.
-
(2005)
FEBS Lett
, vol.579
, pp. 529-533
-
-
Schnitzer, S.E.1
Schmid, T.2
Zhou, J.3
Eisenbrand, G.4
Brune, B.5
-
87
-
-
0033663862
-
Detection and analysis of beta-catenin mutations in prostate cancer
-
Chesire DR, Ewing CM, Sauvageot J, Bova GS, Isaacs WB. Detection and analysis of beta-catenin mutations in prostate cancer. Prostate. 2000;45:323-34.
-
(2000)
Prostate
, vol.45
, pp. 323-334
-
-
Chesire, D.R.1
Ewing, C.M.2
Sauvageot, J.3
Bova, G.S.4
Isaacs, W.B.5
-
88
-
-
77957584397
-
O2 regulates stem cells through Wnt/beta-catenin signalling
-
Mazumdar J, O’Brien WT, Johnson RS, LaManna JC, Chavez JC, Klein PS, Simon MC. O2 regulates stem cells through Wnt/beta-catenin signalling. Nat Cell Biol. 2010;12:1007-13.
-
(2010)
Nat Cell Biol
, vol.12
, pp. 1007-1013
-
-
Mazumdar, J.1
O’Brien, W.T.2
Johnson, R.S.3
Lamanna, J.C.4
Chavez, J.C.5
Klein, P.S.6
Simon, M.C.7
-
89
-
-
84894383636
-
Hypoxia triggers a Nur77-beta-catenin feed-forward loop to promote the invasive growth of colon cancer cells
-
To SK, Zeng WJ, Zeng JZ, Wong AS. Hypoxia triggers a Nur77-beta-catenin feed-forward loop to promote the invasive growth of colon cancer cells. Br J Cancer. 2014;110:935-45.
-
(2014)
Br J Cancer
, vol.110
, pp. 935-945
-
-
To, S.K.1
Zeng, W.J.2
Zeng, J.Z.3
Wong, A.S.4
-
90
-
-
84877157115
-
Wnt/beta-catenin signaling enhances hypoxia-induced epithelial-mesenchymal transition in hepatocellular carcinoma via crosstalk with hif-1alpha signaling
-
Zhang Q, Bai X, Chen W, Ma T, Hu Q, Liang C, Xie S, Chen C, Hu L, Xu S, Liang T. Wnt/beta-catenin signaling enhances hypoxia-induced epithelial-mesenchymal transition in hepatocellular carcinoma via crosstalk with hif-1alpha signaling. Carcinogenesis. 2013;34:962-73.
-
(2013)
Carcinogenesis
, vol.34
, pp. 962-973
-
-
Zhang, Q.1
Bai, X.2
Chen, W.3
Ma, T.4
Hu, Q.5
Liang, C.6
Xie, S.7
Chen, C.8
Hu, L.9
Xu, S.10
Liang, T.11
-
91
-
-
84935483817
-
Hypoxia-inducible factor-1alpha and Wnt/beta-catenin signaling pathways promote the invasion of hypoxic gastric cancer cells
-
Liu HL, Liu D, Ding GR, Liao PF, Zhang JW. Hypoxia-inducible factor-1alpha and Wnt/beta-catenin signaling pathways promote the invasion of hypoxic gastric cancer cells. Mol Med Rep. 2015;12:3365-73.
-
(2015)
Mol Med Rep
, vol.12
, pp. 3365-3373
-
-
Liu, H.L.1
Liu, D.2
Ding, G.R.3
Liao, P.F.4
Zhang, J.W.5
-
92
-
-
48549098557
-
Hypoxia-inducible factor-1alpha obstructs a Wnt signaling pathway by inhibiting the hARD1-mediated activation of beta-catenin
-
Lim JH, Chun YS, Park JW. Hypoxia-inducible factor-1alpha obstructs a Wnt signaling pathway by inhibiting the hARD1-mediated activation of beta-catenin. Cancer Res. 2008;68:5177-84.
-
(2008)
Cancer Res
, vol.68
, pp. 5177-5184
-
-
Lim, J.H.1
Chun, Y.S.2
Park, J.W.3
-
93
-
-
57349163212
-
Tumor hypoxia blocks Wnt processing and secretion through the induction of endoplasmic reticulum stress
-
Verras M, Papandreou I, Lim AL, Denko NC. Tumor hypoxia blocks Wnt processing and secretion through the induction of endoplasmic reticulum stress. Mol Cell Biol. 2008;28:7212-24.
-
(2008)
Mol Cell Biol
, vol.28
, pp. 7212-7224
-
-
Verras, M.1
Papandreou, I.2
Lim, A.L.3
Denko, N.C.4
-
94
-
-
6044243650
-
Hedgehog signalling in prostate regeneration, neoplasia and metastasis
-
Karhadkar SS, Bova GS, Abdallah N, Dhara S, Gardner D, Maitra A, Isaacs JT, Berman DM, Beachy PA. Hedgehog signalling in prostate regeneration, neoplasia and metastasis. Nature. 2004;431:707-12.
-
(2004)
Nature
, vol.431
, pp. 707-712
-
-
Karhadkar, S.S.1
Bova, G.S.2
Abdallah, N.3
Dhara, S.4
Gardner, D.5
Maitra, A.6
Isaacs, J.T.7
Berman, D.M.8
Beachy, P.A.9
-
95
-
-
4344659678
-
Inhibition of prostate cancer proliferation by interference with SONIC HEDGEHOG-GLI1 signaling
-
Sanchez P, Hernandez AM, Stecca B, Kahler AJ, DeGueme AM, Barrett A, Beyna M, Datta MW, Datta S, Ruiz i Altaba A. Inhibition of prostate cancer proliferation by interference with SONIC HEDGEHOG-GLI1 signaling. Proc Natl Acad Sci U S A. 2004;101:12561-6.
-
(2004)
Proc Natl Acad Sci U S A
, vol.101
, pp. 12561-12566
-
-
Sanchez, P.1
Hernandez, A.M.2
Stecca, B.3
Kahler, A.J.4
Degueme, A.M.5
Barrett, A.6
Beyna, M.7
Datta, M.W.8
Datta, S.9
Ruiz I Altaba, A.10
-
96
-
-
84880150812
-
Hedgehog signaling in prostate cancer and its therapeutic implication
-
Gonnissen A, Isebaert S, Haustermans K. Hedgehog signaling in prostate cancer and its therapeutic implication. Int J Mol Sci. 2013;14:13979-4007.
-
(2013)
Int J Mol Sci
, vol.14
, pp. 13979-14007
-
-
Gonnissen, A.1
Isebaert, S.2
Haustermans, K.3
-
97
-
-
79956219871
-
Hypoxia activates the hedgehog signaling pathway in a ligand-independent manner by upregulation of Smo transcription in pancreatic cancer
-
Onishi H, Kai M, Odate S, Iwasaki H, Morifuji Y, Ogino T, Morisaki T, Nakashima Y, Katano M. Hypoxia activates the hedgehog signaling pathway in a ligand-independent manner by upregulation of Smo transcription in pancreatic cancer. Cancer Sci. 2011;102:1144-50.
-
(2011)
Cancer Sci
, vol.102
, pp. 1144-1150
-
-
Onishi, H.1
Kai, M.2
Odate, S.3
Iwasaki, H.4
Morifuji, Y.5
Ogino, T.6
Morisaki, T.7
Nakashima, Y.8
Katano, M.9
-
98
-
-
84879105877
-
Hedgehog signaling regulates hypoxia induced epithelial to mesenchymal transition and invasion in pancreatic cancer cells via a ligand-independent manner
-
Lei J, Ma J, Ma Q, Li X, Liu H, Xu Q, Duan W, Sun Q, Xu J, Wu Z, Wu E. Hedgehog signaling regulates hypoxia induced epithelial to mesenchymal transition and invasion in pancreatic cancer cells via a ligand-independent manner. Mol Cancer. 2013;12:66.
-
(2013)
Mol Cancer
, vol.12
, pp. 66
-
-
Lei, J.1
Ma, J.2
Ma, Q.3
Li, X.4
Liu, H.5
Xu, Q.6
Duan, W.7
Sun, Q.8
Xu, J.9
Wu, Z.10
Wu, E.11
-
99
-
-
84931025000
-
Gli-1 is crucial for hypoxia-induced epithelial-mesenchymal transition and invasion of breast cancer
-
Lei J, Fan L, Wei G, Chen X, Duan W, Xu Q, Sheng W, Wang K, Li X. Gli-1 is crucial for hypoxia-induced epithelial-mesenchymal transition and invasion of breast cancer. Tumour Biol. 2015;36:3119-26.
-
(2015)
Tumour Biol
, vol.36
, pp. 3119-3126
-
-
Lei, J.1
Fan, L.2
Wei, G.3
Chen, X.4
Duan, W.5
Xu, Q.6
Sheng, W.7
Wang, K.8
Li, X.9
-
100
-
-
84908170760
-
Reciprocal regulation of hypoxia-inducible factor 2alpha and GLI1 expression associated with the radioresistance of renal cell carcinoma
-
Zhou J, Wu K, Gao D, Zhu G, Wu D, Wang X, Chen Y, Du Y, Song W, Ma Z, Authement C, Saha D, Hsieh JT, He D. Reciprocal regulation of hypoxia-inducible factor 2alpha and GLI1 expression associated with the radioresistance of renal cell carcinoma. Int J Radiat Oncol Biol Phys. 2014;90:942-51.
-
(2014)
Int J Radiat Oncol Biol Phys
, vol.90
, pp. 942-951
-
-
Zhou, J.1
Wu, K.2
Gao, D.3
Zhu, G.4
Wu, D.5
Wang, X.6
Chen, Y.7
Du, Y.8
Song, W.9
Ma, Z.10
Authement, C.11
Saha, D.12
Hsieh, J.T.13
He, D.14
-
101
-
-
84876927914
-
Exosomes reflect the hypoxic status of glioma cells and mediate hypoxia-dependent activation of vascular cells during tumor development
-
Kucharzewska P, Christianson HC, Welch JE, Svensson KJ, Fredlund E, Ringner M, Morgelin M, Bourseau-Guilmain E, Bengzon J, Belting M. Exosomes reflect the hypoxic status of glioma cells and mediate hypoxia-dependent activation of vascular cells during tumor development. Proc Natl Acad Sci U S A. 2013;110:7312-7.
-
(2013)
Proc Natl Acad Sci U S A
, vol.110
, pp. 7312-7317
-
-
Kucharzewska, P.1
Christianson, H.C.2
Welch, J.E.3
Svensson, K.J.4
Fredlund, E.5
Ringner, M.6
Morgelin, M.7
Bourseau-Guilmain, E.8
Bengzon, J.9
Belting, M.10
-
102
-
-
84919680938
-
Exosomal miR-135b shed from hypoxic multiple myeloma cells enhances angiogenesis by targeting factor-inhibiting HIF-1
-
Umezu T, Tadokoro H, Azuma K, Yoshizawa S, Ohyashiki K, Ohyashiki JH. Exosomal miR-135b shed from hypoxic multiple myeloma cells enhances angiogenesis by targeting factor-inhibiting HIF-1. Blood. 2014;124:3748-57.
-
(2014)
Blood
, vol.124
, pp. 3748-3757
-
-
Umezu, T.1
Tadokoro, H.2
Azuma, K.3
Yoshizawa, S.4
Ohyashiki, K.5
Ohyashiki, J.H.6
-
103
-
-
84888986034
-
Exosomes derived from hypoxic leukemia cells enhance tube formation in endothelial cells
-
Tadokoro H, Umezu T, Ohyashiki K, Hirano T, Ohyashiki JH. Exosomes derived from hypoxic leukemia cells enhance tube formation in endothelial cells. J Biol Chem. 2013;288:34343-51.
-
(2013)
J Biol Chem
, vol.288
, pp. 34343-34351
-
-
Tadokoro, H.1
Umezu, T.2
Ohyashiki, K.3
Hirano, T.4
Ohyashiki, J.H.5
-
104
-
-
84905643012
-
Hypoxia-inducible factors and RAB22A mediate formation of microvesicles that stimulate breast cancer invasion and metastasis
-
Wang T, Gilkes DM, Takano N, Xiang L, Luo W, Bishop CJ, Chaturvedi P, Green JJ, Semenza GL. Hypoxia-inducible factors and RAB22A mediate formation of microvesicles that stimulate breast cancer invasion and metastasis. Proc Natl Acad Sci U S A. 2014;111:E3234-42.
-
(2014)
Proc Natl Acad Sci U S A
, vol.111
, pp. 3234-e3242
-
-
Wang, T.1
Gilkes, D.M.2
Takano, N.3
Xiang, L.4
Luo, W.5
Bishop, C.J.6
Chaturvedi, P.7
Green, J.J.8
Semenza, G.L.9
-
105
-
-
84890313522
-
Exosomes in cancer development, metastasis, and drug resistance: A comprehensive review
-
Azmi AS, Bao B, Sarkar FH. Exosomes in cancer development, metastasis, and drug resistance: a comprehensive review. Cancer Metast Rev. 2013;32:623-42.
-
(2013)
Cancer Metast Rev
, vol.32
, pp. 623-642
-
-
Azmi, A.S.1
Bao, B.2
Sarkar, F.H.3
-
106
-
-
71749102668
-
Microenvironmental pH is a key factor for exosome traffic in tumor cells
-
Parolini I, Federici C, Raggi C, Lugini L, Palleschi S, De Milito A, Coscia C, Iessi E, Logozzi M, Molinari A, Colone M, Tatti M, Sargiacomo M, Fais S. Microenvironmental pH is a key factor for exosome traffic in tumor cells. J Biol Chem. 2009;284:34211-22.
-
(2009)
J Biol Chem
, vol.284
, pp. 34211-34222
-
-
Parolini, I.1
Federici, C.2
Raggi, C.3
Lugini, L.4
Palleschi, S.5
De Milito, A.6
Coscia, C.7
Iessi, E.8
Logozzi, M.9
Molinari, A.10
Colone, M.11
Tatti, M.12
Sargiacomo, M.13
Fais, S.14
-
107
-
-
77953142134
-
Hypoxic tumor cell modulates its microenvironment to enhance angiogenic and metastatic potential by secretion of proteins and exosomes
-
Park JE, Tan HS, Datta A, Lai RC, Zhang H, Meng W, Lim SK, Sze SK. Hypoxic tumor cell modulates its microenvironment to enhance angiogenic and metastatic potential by secretion of proteins and exosomes. Mol Cell Proteomics. 2010;9:1085-99.
-
(2010)
Mol Cell Proteomics
, vol.9
, pp. 1085-1099
-
-
Park, J.E.1
Tan, H.S.2
Datta, A.3
Lai, R.C.4
Zhang, H.5
Meng, W.6
Lim, S.K.7
Sze, S.K.8
-
108
-
-
84896408214
-
Exosomal HIF1alpha supports invasive potential of nasopharyngeal carcinoma-associated LMP1-positive exosomes
-
Aga M, Bentz GL, Raffa S, Torrisi MR, Kondo S, Wakisaka N, Yoshizaki T, Pagano JS, Shackelford J. Exosomal HIF1alpha supports invasive potential of nasopharyngeal carcinoma-associated LMP1-positive exosomes. Oncogene. 2014;33:4613-22.
-
(2014)
Oncogene
, vol.33
, pp. 4613-4622
-
-
Aga, M.1
Bentz, G.L.2
Raffa, S.3
Torrisi, M.R.4
Kondo, S.5
Wakisaka, N.6
Yoshizaki, T.7
Pagano, J.S.8
Shackelford, J.9
-
109
-
-
84896091950
-
Lipid synthesis is promoted by hypoxic adipocyte-derived exosomes in 3T3-L1 cells
-
Sano S, Izumi Y, Yamaguchi T, Yamazaki T, Tanaka M, Shiota M, Osada-Oka M, Nakamura Y, Wei M, Wanibuchi H, Iwao H, Yoshiyama M. Lipid synthesis is promoted by hypoxic adipocyte-derived exosomes in 3T3-L1 cells. Biochem Biophys Res Commun. 2014;445:327-33.
-
(2014)
Biochem Biophys Res Commun
, vol.445
, pp. 327-333
-
-
Sano, S.1
Izumi, Y.2
Yamaguchi, T.3
Yamazaki, T.4
Tanaka, M.5
Shiota, M.6
Osada-Oka, M.7
Nakamura, Y.8
Wei, M.9
Wanibuchi, H.10
Iwao, H.11
Yoshiyama, M.12
-
110
-
-
84897062699
-
Exosomal Proteome Profiling: A Potential Multi-Marker Cellular Phenotyping Tool to Characterize Hypoxia-Induced Radiation Resistance in Breast Cancer
-
Thomas SN, Liao Z, Clark D, Chen Y, Samadani R, Mao L, Ann DK, Baulch JE, Shapiro P, Yang AJ. Exosomal Proteome Profiling: A Potential Multi-Marker Cellular Phenotyping Tool to Characterize Hypoxia-Induced Radiation Resistance in Breast Cancer. Proteomes. 2013;1:87-108.
-
(2013)
Proteomes
, vol.1
, pp. 87-108
-
-
Thomas, S.N.1
Liao, Z.2
Clark, D.3
Chen, Y.4
Samadani, R.5
Mao, L.6
Ann, D.K.7
Baulch, J.E.8
Shapiro, P.9
Yang, A.J.10
-
111
-
-
1842426907
-
Up-regulation of hypoxia-inducible factor 1alpha is an early event in prostate carcinogenesis
-
Zhong H, Semenza GL, Simons JW, De Marzo AM. Up-regulation of hypoxia-inducible factor 1alpha is an early event in prostate carcinogenesis. Cancer Detect Prevent. 2004;28:88-93.
-
(2004)
Cancer Detect Prevent
, vol.28
, pp. 88-93
-
-
Zhong, H.1
Semenza, G.L.2
Simons, J.W.3
De Marzo, A.M.4
-
112
-
-
36448933775
-
Usefulness of hypoxia inducible factor-1 alpha in evaluating the prostatic adenocarcinoma viability following neoadjuvant hormone therapy
-
Yasuda M, Shimizu M, Fujita M, Miyazawa M, Tang X, Kajiwara H, Osamura RY, Shoji S, Tokunaga M, Terachi T. Usefulness of hypoxia inducible factor-1 alpha in evaluating the prostatic adenocarcinoma viability following neoadjuvant hormone therapy. Cancer Detect Prevent. 2007;31:396-401.
-
(2007)
Cancer Detect Prevent
, vol.31
, pp. 396-401
-
-
Yasuda, M.1
Shimizu, M.2
Fujita, M.3
Miyazawa, M.4
Tang, X.5
Kajiwara, H.6
Osamura, R.Y.7
Shoji, S.8
Tokunaga, M.9
Terachi, T.10
-
113
-
-
0033571682
-
Overexpression of hypoxia-inducible factor 1alpha in common human cancers and their metastases
-
Zhong H, De Marzo AM, Laughner E, Lim M, Hilton DA, Zagzag D, Buechler P, Isaacs WB, Semenza GL, Simons JW. Overexpression of hypoxia-inducible factor 1alpha in common human cancers and their metastases. Cancer Res. 1999;59:5830-5.
-
(1999)
Cancer Res
, vol.59
, pp. 5830-5835
-
-
Zhong, H.1
De Marzo, A.M.2
Laughner, E.3
Lim, M.4
Hilton, D.A.5
Zagzag, D.6
Buechler, P.7
Isaacs, W.B.8
Semenza, G.L.9
Simons, J.W.10
-
114
-
-
0742271629
-
Expression of hypoxia-inducible factor 1alpha in human normal, benign, and malignant prostate tissue
-
Du Z, Fujiyama C, Chen Y, Masaki Z. Expression of hypoxia-inducible factor 1alpha in human normal, benign, and malignant prostate tissue. Chin Med J. 2003;116:1936-9.
-
(2003)
Chin Med J
, vol.116
, pp. 1936-1939
-
-
Du, Z.1
Fujiyama, C.2
Chen, Y.3
Masaki, Z.4
-
115
-
-
58049194196
-
HIF-1alpha mRNA gene expression levels in improved diagnosis of early stages of prostate cancer
-
Pipinikas CP, Carter ND, Corbishley CM, Fenske CD. HIF-1alpha mRNA gene expression levels in improved diagnosis of early stages of prostate cancer. Biomarkers. 2008;13:680-91.
-
(2008)
Biomarkers
, vol.13
, pp. 680-691
-
-
Pipinikas, C.P.1
Carter, N.D.2
Corbishley, C.M.3
Fenske, C.D.4
-
116
-
-
59249087947
-
Analysis of hypoxia-associated gene expression in prostate cancer: Lysyl oxidase and glucose transporter-1 expression correlate with Gleason score
-
Stewart GD, Gray K, Pennington CJ, Edwards DR, Riddick AC, Ross JA, Habib FK. Analysis of hypoxia-associated gene expression in prostate cancer: lysyl oxidase and glucose transporter-1 expression correlate with Gleason score. Oncol Rep. 2008;20:1561-7.
-
(2008)
Oncol Rep
, vol.20
, pp. 1561-1567
-
-
Stewart, G.D.1
Gray, K.2
Pennington, C.J.3
Edwards, D.R.4
Riddick, A.C.5
Ross, J.A.6
Habib, F.K.7
-
117
-
-
33646007333
-
An immunohistochemical assessment of hypoxia in prostate carcinoma using pimonidazole: Implications for radioresistance
-
Carnell DM, Smith RE, Daley FM, Saunders MI, Bentzen SM, Hoskin PJ. An immunohistochemical assessment of hypoxia in prostate carcinoma using pimonidazole: implications for radioresistance. Int J Radiat Oncol Biol Phys. 2006;65:91-9.
-
(2006)
Int J Radiat Oncol Biol Phys
, vol.65
, pp. 91-99
-
-
Carnell, D.M.1
Smith, R.E.2
Daley, F.M.3
Saunders, M.I.4
Bentzen, S.M.5
Hoskin, P.J.6
-
118
-
-
84856405075
-
Hypoxic prostate/muscle PO2 ratio predicts for outcome in patients with localized prostate cancer: Long-term results
-
Turaka A, Buyyounouski MK, Hanlon AL, Horwitz EM, Greenberg RE, Movsas B. Hypoxic prostate/muscle PO2 ratio predicts for outcome in patients with localized prostate cancer: long-term results. Int J Radiat Oncol Biol Phys. 2012;82:e433-9.
-
(2012)
Int J Radiat Oncol Biol Phys
, vol.82
, pp. 433-e439
-
-
Turaka, A.1
Buyyounouski, M.K.2
Hanlon, A.L.3
Horwitz, E.M.4
Greenberg, R.E.5
Movsas, B.6
-
119
-
-
79959922456
-
A novel two-stage, transdisciplinary study identifies digoxin as a possible drug for prostate cancer treatment
-
Platz EA, Yegnasubramanian S, Liu JO, Chong CR, Shim JS, Kenfield SA, Stampfer MJ, Willett WC, Giovannucci E, Nelson WG. A novel two-stage, transdisciplinary study identifies digoxin as a possible drug for prostate cancer treatment. Cancer Discov. 2011;1:68-77.
-
(2011)
Cancer Discov
, vol.1
, pp. 68-77
-
-
Platz, E.A.1
Yegnasubramanian, S.2
Liu, J.O.3
Chong, C.R.4
Shim, J.S.5
Kenfield, S.A.6
Stampfer, M.J.7
Willett, W.C.8
Giovannucci, E.9
Nelson, W.G.10
-
120
-
-
84920271526
-
The effects of nonspecific HIF1alpha inhibitors on development of castrate resistance and metastases in prostate cancer
-
Ranasinghe WK, Sengupta S, Williams S, Chang M, Shulkes A, Bolton DM, Baldwin G, Patel O. The effects of nonspecific HIF1alpha inhibitors on development of castrate resistance and metastases in prostate cancer. Cancer Med. 2014;3:245-51.
-
(2014)
Cancer Med
, vol.3
, pp. 245-251
-
-
Ranasinghe, W.K.1
Sengupta, S.2
Williams, S.3
Chang, M.4
Shulkes, A.5
Bolton, D.M.6
Baldwin, G.7
Patel, O.8
-
121
-
-
34547098129
-
Targeting hypoxia cell signaling for cancer therapy
-
Melillo G. Targeting hypoxia cell signaling for cancer therapy. Cancer Metast Rev. 2007;26:341-52.
-
(2007)
Cancer Metast Rev
, vol.26
, pp. 341-352
-
-
Melillo, G.1
|