Hedgehog signaling regulates hypoxia induced epithelial to mesenchymal transition and invasion in pancreatic cancer cells via a ligand-independent manner

Molecular Cancer

Volumn 12, Issue 1, 2013, Pages

  Lei, Jianjun ^a   Ma, Jiguang ^a   Ma, Qingyong ^a   Li, Xuqi ^a   Liu, Han ^a   Xu, Qinhong ^a   Duan, Wanxing ^a   Sun, Qing ^a   Xu, Jun ^a   Wu, Zheng ^a   Wu, Erxi ^b  

^a XI'AN JIAOTONG UNIVERSITY   (China)

^b NORTH DAKOTA STATE UNIVERSITY   (United States)

Author keywords

Epithelial to mesenchymal transition; Hedgehog signaling; Hypoxia; Invasion; Pancreatic cancer

Indexed keywords

CYCLOPAMINE; K RAS PROTEIN; LIGAND; SMALL INTERFERING RNA; TRANSFORMING GROWTH FACTOR BETA; VIMENTIN;

ARTICLE; BLOOD LEVEL; CANCER GROWTH; EPITHELIAL MESENCHYMAL TRANSITION; HEDGEHOG; HUMAN; HUMAN CELL; HYPOXIA; PANCREAS CANCER; PROTEIN EXPRESSION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION;

CELL HYPOXIA; CELL LINE, TUMOR; EPITHELIAL-MESENCHYMAL TRANSITION; GENE EXPRESSION; GENE SILENCING; HEDGEHOG PROTEINS; HUMANS; HYPOXIA-INDUCIBLE FACTOR 1, ALPHA SUBUNIT; LIGANDS; MODELS, BIOLOGICAL; NEOPLASM INVASIVENESS; ONCOGENE PROTEINS; PANCREATIC NEOPLASMS; PHENOTYPE; RECEPTORS, G-PROTEIN-COUPLED; SIGNAL TRANSDUCTION; TRANS-ACTIVATORS;

ERINACEIDAE;

EID: 84879105877     PISSN: None     EISSN: 14764598     Source Type: Journal    
DOI: 10.1186/1476-4598-12-66     Document Type: Article

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