Lipid synthesis is promoted by hypoxic adipocyte-derived exosomes in 3T3-L1 cells

Biochemical and Biophysical Research Communications

Volumn 445, Issue 2, 2014, Pages 327-333

  Sano, Soichi ^a   Izumi, Yasukatsu ^a   Yamaguchi, Takehiro ^a   Yamazaki, Takanori ^a   Tanaka, Masako ^a   Shiota, Masayuki ^a   Osada Oka, Mayuko ^b   Nakamura, Yasuhiro ^c   Wei, Min ^a   Wanibuchi, Hideki ^a   Iwao, Hiroshi ^a   Yoshiyama, Minoru ^a  

^a OSAKA CITY UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^b KYOTO PREFECTURAL UNIVERSITY   (Japan)

^c Izumi Municipal Hospital   (Japan)

Author keywords

Adipocytes; De novo lipogenesis; Exosome; Hypoxia; Proteomic analysis

Indexed keywords

ADIPOCYTE; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CELL HYPOXIA; CELL STRAIN 3T3; CONTROLLED STUDY; EXOSOME; HUMAN; HUMAN CELL; LIPOGENESIS; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROADIPOCYTE; PROTEIN CONTENT; PROTEOMICS; QUANTITATIVE ANALYSIS;

ADIPOCYTES; DE NOVO LIPOGENESIS; EXOSOME; HYPOXIA; PROTEOMIC ANALYSIS;

3T3-L1 CELLS; ANIMALS; CELL HYPOXIA; EXOSOMES; HEK293 CELLS; HUMANS; LIPOGENESIS; MICE; OBESITY; PROTEOME;

EID: 84896091950     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2014.01.183     Document Type: Article

References (33)

1. H. van den Bosch Phosphoglyceride metabolism Annu. Rev. Biochem. 43 1974 243 277
2. E.D. Rosen, and B.M. Spiegelman Adipocytes as regulators of energy balance and glucose homeostasis Nature 444 2006 847 853 (Pubitemid 46024991)
3. A.H. Mokdad, E.S. Ford, B.A. Bowman, W.H. Dietz, F. Vinicor, V.S. Bales, and J.S. Marks Prevalence of obesity, diabetes, and obesity-related health risk factors, 2001 JAMA 289 2003 76 79 (Pubitemid 36026281)
4. L.F. Van Gaal, I.L. Mertens, and C.E. De Block Mechanisms linking obesity with cardiovascular disease Nature 444 2006 875 880 (Pubitemid 46028447)
5. S.E. Kahn, R.L. Hull, and K.M. Utzschneider Mechanisms linking obesity to insulin resistance and type 2 diabetes Nature 444 2006 840 846 (Pubitemid 46024990)
6. P. Bjorntorp Adipose tissue distribution and function Int. J. Obes. 15 Suppl. 2 1991 67 81
7. M. Dunlop, and J.M. Court Lipogenesis in developing human adipose tissue Early Hum. Dev. 2 1978 123 130 (Pubitemid 8406422)
8. G.P. Laliotis, I. Bizelis, and E. Rogdakis Comparative approach of the de novo fatty acid synthesis (lipogenesis) between ruminant and non ruminant mammalian species: from biochemical level to the main regulatory lipogenic genes Curr. Genomics 11 2010 168 183
9. T. Hashimoto, T. Yokokawa, Y. Endo, N. Iwanaka, K. Higashida, and S. Taguchi Modest hypoxia significantly reduces triglyceride content and lipid droplet size in 3T3-L1 adipocytes Biochem. Biophys. Res. Commun. 440 2013 43 49
10. S.W. Cushman, and L.B. Salans Determinations of adipose cell size and number in suspensions of isolated rat and human adipose cells J. Lipid Res. 19 1978 269 273 (Pubitemid 8288809)
11. G. Muller Let's shift lipid burden - from large to small adipocytes Eur. J. Pharmacol. 656 2011 1 4
12. B.T. Pan, and R.M. Johnstone Fate of the transferrin receptor during maturation of sheep reticulocytes in vitro: selective externalization of the receptor Cell 33 1983 967 978
13. J.S. Schorey, and S. Bhatnagar Exosome function: from tumor immunology to pathogen biology Traffic 9 2008 871 881 (Pubitemid 351639493)
14. S. Mathivanan, H. Ji, and R.J. Simpson Exosomes: extracellular organelles important in intercellular communication J. Proteomics 73 2010 1907 1920
15. O.G. de Jong, M.C. Verhaar, Y. Chen, P. Vader, H. Gremmels, G. Posthuma, R.M. Schiffelers, M. Gucek, and B.W. van Balkom Cellular stress conditions are reflected in the protein and RNA content of endothelial cell-derived exosomes J. Extracell Vesicles 1 2012
16. A.S. Azmi, B. Bao, and F.H. Sarkar Exosomes in cancer development, metastasis, and drug resistance: a comprehensive review Cancer Metastasis Rev. 32 2013 623 642
17. P. Kucharzewska, H.C. Christianson, J.E. Welch, K.J. Svensson, E. Fredlund, M. Ringner, M. Morgelin, E. Bourseau-Guilmain, J. Bengzon, and M. Belting Exosomes reflect the hypoxic status of glioma cells and mediate hypoxia-dependent activation of vascular cells during tumor development Proc. Natl. Acad. Sci. U.S.A. 110 2013 7312 7317
18. H. Tadokoro, T. Umezu, K. Ohyashiki, T. Hirano, and J.H. Ohyashiki Exosomes derived from hypoxic leukemia cells enhance tube formation in endothelial cells J. Biol. Chem. 288 2013 34343 34351
19. S. Yu, C. Liu, K. Su, J. Wang, Y. Liu, L. Zhang, C. Li, Y. Cong, R. Kimberly, W.E. Grizzle, C. Falkson, and H.G. Zhang Tumor exosomes inhibit differentiation of bone marrow dendritic cells J. Immunol. 178 2007 6867 6875 (Pubitemid 46847412)
20. G. Muller, C. Jung, J. Straub, S. Wied, and W. Kramer Induced release of membrane vesicles from rat adipocytes containing glycosylphosphatidylinositol- anchored microdomain and lipid droplet signalling proteins Cell. Signal. 21 2009 324 338
21. K. Takahashi, M. Tanaka, A. Inagaki, H. Wanibuchi, Y. Izumi, K. Miura, K. Nagayama, M. Shiota, and H. Iwao Establishment of a 5-fluorouracil-resistant triple-negative breast cancer cell line Int. J. Oncol. 43 2013 1985 1991
22. P. Trayhurn Hypoxia and adipose tissue function and dysfunction in obesity Physiol. Rev. 93 2013 1 21
23. M. Eldh, K. Ekstrom, H. Valadi, M. Sjostrand, B. Olsson, M. Jernas, and J. Lotvall Exosomes communicate protective messages during oxidative stress; possible role of exosomal shuttle RNA PLoS ONE 5 2010 e15353
24. P. Trayhurn, and I.S. Wood Adipokines: inflammation and the pleiotropic role of white adipose tissue Br. J. Nutr. 92 2004 347 355 (Pubitemid 40277057)
25. B.T. Pan, K. Teng, C. Wu, M. Adam, and R.M. Johnstone Electron microscopic evidence for externalization of the transferrin receptor in vesicular form in sheep reticulocytes J. Cell Biol. 101 1985 942 948 (Pubitemid 16256847)
26. D. Marimpietri, A. Petretto, L. Raffaghello, A. Pezzolo, C. Gagliani, C. Tacchetti, P. Mauri, G. Melioli, and V. Pistoia Proteome profiling of neuroblastoma-derived exosomes reveal the expression of proteins potentially involved in tumor progression PLoS ONE 8 2013 e75054
27. K. Strauss, C. Goebel, H. Runz, W. Mobius, S. Weiss, I. Feussner, M. Simons, and A. Schneider Exosome secretion ameliorates lysosomal storage of cholesterol in Niemann-Pick type C disease J. Biol. Chem. 285 2010 26279 26288
28. H.W. King, M.Z. Michael, and J.M. Gleadle Hypoxic enhancement of exosome release by breast cancer cells BMC Cancer 12 2012 421
29. J.D. Paulauskis, and H.S. Sul Cloning and expression of mouse fatty acid synthase and other specific mRNAs. Developmental and hormonal regulation in 3T3-L1 cells J. Biol. Chem. 263 1988 7049 7054
30. J. Park, S.S. Choe, A.H. Choi, K.H. Kim, M.J. Yoon, T. Suganami, Y. Ogawa, and J.B. Kim Increase in glucose-6-phosphate dehydrogenase in adipocytes stimulates oxidative stress and inflammatory signals Diabetes 55 2006 2939 2949 (Pubitemid 44929428)
31. K.L. Levert, G.L. Waldrop, and J.M. Stephens A biotin analog inhibits acetyl-CoA carboxylase activity and adipogenesis J. Biol. Chem. 277 2002 16347 16350 (Pubitemid 34967642)
32. J. Park, H.K. Rho, K.H. Kim, S.S. Choe, Y.S. Lee, and J.B. Kim Overexpression of glucose-6-phosphate dehydrogenase is associated with lipid dysregulation and insulin resistance in obesity Mol. Cell. Biol. 25 2005 5146 5157 (Pubitemid 40781113)
33. J.M. Fernandez-Real, J.A. Menendez, J.M. Moreno-Navarrete, M. Bluher, A. Vazquez-Martin, M.J. Vazquez, F. Ortega, C. Dieguez, G. Fruhbeck, W. Ricart, and A. Vidal-Puig Extracellular fatty acid synthase: a possible surrogate biomarker of insulin resistance Diabetes 59 2010 1506 1511