Induction of HIF-1α expression by intermittent hypoxia: Involvement of NADPH oxidase, Ca2+ signaling, prolyl hydroxylases, and mTOR

Journal of Cellular Physiology

Volumn 217, Issue 3, 2008, Pages 674-685

  Yuan, Guoxiang ^a   Nanduri, Jayasri ^a   Khan, Shakil ^a   Semenza, Gregg L ^b   Prabhakar, Nanduri R ^a,c  

^a UNIVERSITY OF CHICAGO   (United States)

^b JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c Center for Systems Biology   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CALCIUM ION; CYCLOHEXIMIDE; HYPOXIA INDUCIBLE FACTOR 1ALPHA; MAMMALIAN TARGET OF RAPAMYCIN; PHOSPHOLIPASE C GAMMA; PROCOLLAGEN PROLINE 2 OXOGLUTARATE 4 DIOXYGENASE; PROTEIN KINASE C; RAPAMYCIN; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE; S6 KINASE; CALCIUM; OXYGEN; PROTEIN KINASE;

ANIMAL CELL; ANTIOXIDANT ACTIVITY; ARTICLE; CALCIUM SIGNALING; CHRONIC INTERMITTENT HYPOXIA; COMORBIDITY; CONTROLLED STUDY; ENZYME REGULATION; HYDROXYLATION; HYPOXIA; MOLECULAR MECHANICS; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; SLEEP DISORDERED BREATHING; ANIMAL; BIOLOGICAL MODEL; CELL HYPOXIA; CELL STRAIN; DRUG EFFECT; ENZYME ACTIVATION; METABOLISM; PROTEIN SYNTHESIS; RAT; THERMODYNAMICS;

MUS;

ANIMALS; CALCIUM; CALCIUM SIGNALING; CELL HYPOXIA; ENZYME ACTIVATION; HYDROXYLATION; HYPOXIA-INDUCIBLE FACTOR 1, ALPHA SUBUNIT; MICE; MODELS, BIOLOGICAL; NADPH OXIDASE; OXYGEN; PC12 CELLS; PHOSPHOLIPASE C GAMMA; PROCOLLAGEN-PROLINE DIOXYGENASE; PROTEIN BIOSYNTHESIS; PROTEIN KINASE C; PROTEIN KINASES; RATS; REACTIVE OXYGEN SPECIES; RIBOSOMAL PROTEIN S6 KINASES; SIROLIMUS; THERMODYNAMICS;

EID: 54049088213     PISSN: 00219541     EISSN: None     Source Type: Journal    
DOI: 10.1002/jcp.21537     Document Type: Article

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