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Volumn 28, Issue 23, 2008, Pages 7212-7224

Tumor hypoxia blocks Wnt processing and secretion through the induction of endoplasmic reticulum stress

Author keywords

[No Author keywords available]

Indexed keywords

BETA CATENIN; CHAPERONE; MUTANT PROTEIN; PROTEIN WNT 16; UNCLASSIFIED DRUG; WNT PROTEIN;

EID: 57349163212     PISSN: 02707306     EISSN: None     Source Type: Journal    
DOI: 10.1128/MCB.00947-08     Document Type: Article
Times cited : (67)

References (37)
  • 1
    • 33751217466 scopus 로고    scopus 로고
    • Tumor morphology and phenotypic evolution driven by selective pressure from the microenvironment
    • Anderson, A. R., A. M. Weaver, P. T. Cummings, and V. Quaranta. 2006. Tumor morphology and phenotypic evolution driven by selective pressure from the microenvironment. Cell 127:905-915.
    • (2006) Cell , vol.127 , pp. 905-915
    • Anderson, A.R.1    Weaver, A.M.2    Cummings, P.T.3    Quaranta, V.4
  • 2
    • 33646134826 scopus 로고    scopus 로고
    • Wntless, a conserved membrane protein dedicated to the secretion of Wnt proteins from signaling cells
    • Banziger, C., D. Soldini, C. Schutt, P. Zipperlen, G. Hausmann, and K. Basler. 2006. Wntless, a conserved membrane protein dedicated to the secretion of Wnt proteins from signaling cells. Cell 125:509-522.
    • (2006) Cell , vol.125 , pp. 509-522
    • Banziger, C.1    Soldini, D.2    Schutt, C.3    Zipperlen, P.4    Hausmann, G.5    Basler, K.6
  • 3
    • 0033609070 scopus 로고    scopus 로고
    • T-cell factor-activated transcription is not sufficient to induce anchorage-independent growth of epithelial cells expressing mutant beta-catenin
    • Barth, A. I., D. B. Stewart, and W. J. Nelson. 1999. T-cell factor-activated transcription is not sufficient to induce anchorage-independent growth of epithelial cells expressing mutant beta-catenin. Proc. Natl. Acad. Sci. USA 96:4947-4952.
    • (1999) Proc. Natl. Acad. Sci. USA , vol.96 , pp. 4947-4952
    • Barth, A.I.1    Stewart, D.B.2    Nelson, W.J.3
  • 4
    • 33646123992 scopus 로고    scopus 로고
    • Secretion of Wnt ligands requires Evi, a conserved transmembrane protein
    • Bartscherer, K., N. Pelte, D. Ingelfinger, and M. Boutros. 2006. Secretion of Wnt ligands requires Evi, a conserved transmembrane protein. Cell 125:523-533.
    • (2006) Cell , vol.125 , pp. 523-533
    • Bartscherer, K.1    Pelte, N.2    Ingelfinger, D.3    Boutros, M.4
  • 6
    • 0032053823 scopus 로고    scopus 로고
    • The unique physiology of solid tumors: Opportunities (and problems) for cancer therapy
    • Brown, J. M., and A. J. Giaccia. 1998. The unique physiology of solid tumors: opportunities (and problems) for cancer therapy. Cancer Res. 58:1408-1416.
    • (1998) Cancer Res , vol.58 , pp. 1408-1416
    • Brown, J.M.1    Giaccia, A.J.2
  • 7
    • 0029150726 scopus 로고
    • Biochemical analysis of murine Wnt proteins reveals both shared and distinct properties
    • Burrus, L. W., and A. P. McMahon. 1995. Biochemical analysis of murine Wnt proteins reveals both shared and distinct properties. Exp. Cell Res. 220:363-373.
    • (1995) Exp. Cell Res , vol.220 , pp. 363-373
    • Burrus, L.W.1    McMahon, A.P.2
  • 9
    • 14044271131 scopus 로고    scopus 로고
    • The human protein disulphide isomerase family: Substrate interactions and functional properties
    • Ellgaard, L., and L. W. Ruddock. 2005. The human protein disulphide isomerase family: substrate interactions and functional properties. EMBO Rep. 6:28-32.
    • (2005) EMBO Rep , vol.6 , pp. 28-32
    • Ellgaard, L.1    Ruddock, L.W.2
  • 11
    • 0038359353 scopus 로고    scopus 로고
    • Caught up in a Wnt storm: Wnt signaling in cancer
    • Giles, R. H., J. H. van Es, and H. Clevers. 2003. Caught up in a Wnt storm: Wnt signaling in cancer. Biochim. Biophys. Acta 1653:1-24.
    • (2003) Biochim. Biophys. Acta , vol.1653 , pp. 1-24
    • Giles, R.H.1    van Es, J.H.2    Clevers, H.3
  • 12
    • 0030025773 scopus 로고    scopus 로고
    • Hypoxia-mediated selection of cells with diminished apoptotic potential in solid tumours
    • Graeber, T. G., C. Osmanian, T. Jacks, D. E. Housman, C. J. Koch, S. W. Lowe, and A. J. Giaccia. 1996. Hypoxia-mediated selection of cells with diminished apoptotic potential in solid tumours. Nature 379:88-91.
    • (1996) Nature , vol.379 , pp. 88-91
    • Graeber, T.G.1    Osmanian, C.2    Jacks, T.3    Housman, D.E.4    Koch, C.J.5    Lowe, S.W.6    Giaccia, A.J.7
  • 13
    • 4444265582 scopus 로고    scopus 로고
    • Degradation of misfolded proteins prevents ER-derived oxidative stress and cell death
    • Haynes, C. M., E. A. Titus, and A. A. Cooper. 2004. Degradation of misfolded proteins prevents ER-derived oxidative stress and cell death. Mol. Cell 15:767-776.
    • (2004) Mol. Cell , vol.15 , pp. 767-776
    • Haynes, C.M.1    Titus, E.A.2    Cooper, A.A.3
  • 14
    • 0037349750 scopus 로고    scopus 로고
    • Expression and significance of PTEN, hypoxia-inducible factor-1 alpha in colorectal adenoma and adenocarcinoma
    • Jiang, Y. A., L. F. Fan, C. Q. Jiang, Y. Y. Zhang, H. S. Luo, Z. J. Tang, D. Xia, and M. Wang. 2003. Expression and significance of PTEN, hypoxia-inducible factor-1 alpha in colorectal adenoma and adenocarcinoma. World J. Gastroenterol. 9:491-494.
    • (2003) World J. Gastroenterol , vol.9 , pp. 491-494
    • Jiang, Y.A.1    Fan, L.F.2    Jiang, C.Q.3    Zhang, Y.Y.4    Luo, H.S.5    Tang, Z.J.6    Xia, D.7    Wang, M.8
  • 15
    • 33947217823 scopus 로고    scopus 로고
    • Interaction between beta-catenin and HIF-1 promotes cellular adaptation to hypoxia
    • Kaidi, A., A. C. Williams, and C. Paraskeva. 2007. Interaction between beta-catenin and HIF-1 promotes cellular adaptation to hypoxia. Nat. Cell Biol. 9:210-217.
    • (2007) Nat. Cell Biol , vol.9 , pp. 210-217
    • Kaidi, A.1    Williams, A.C.2    Paraskeva, C.3
  • 16
    • 0026601297 scopus 로고
    • Interaction of Wnt-1 proteins with the binding protein BiP
    • Kitajewski, J., J. O. Mason, and H. E. Varmus. 1992. Interaction of Wnt-1 proteins with the binding protein BiP. Mol. Cell. Biol. 12:784-790.
    • (1992) Mol. Cell. Biol , vol.12 , pp. 784-790
    • Kitajewski, J.1    Mason, J.O.2    Varmus, H.E.3
  • 17
    • 0028294349 scopus 로고
    • The regulation of GRP78 and messenger RNA levels by hypoxia is modulated by protein kinase C activators and inhibitors
    • Koong, A. C., E. A. Auger, E. Y. Chen, and A. J. Giaccia. 1994. The regulation of GRP78 and messenger RNA levels by hypoxia is modulated by protein kinase C activators and inhibitors. Radiat Res. 138:S60-S63.
    • (1994) Radiat Res , vol.138
    • Koong, A.C.1    Auger, E.A.2    Chen, E.Y.3    Giaccia, A.J.4
  • 18
    • 36248988054 scopus 로고    scopus 로고
    • Ubiquitin ligases, critical mediators of endoplasmic reticulum-associated degradation
    • Kostova, Z., Y. C. Tsai, and A. M. Weissman. 2007. Ubiquitin ligases, critical mediators of endoplasmic reticulum-associated degradation. Semin. Cell Dev. Biol. 18:770-779.
    • (2007) Semin. Cell Dev. Biol , vol.18 , pp. 770-779
    • Kostova, Z.1    Tsai, Y.C.2    Weissman, A.M.3
  • 19
    • 33746886623 scopus 로고    scopus 로고
    • Translating tumor hypoxia: Unfolded protein response (UPR)-dependent and UPR-independent pathways
    • Koumenis, C., and B. G. Wouters. 2006. "Translating" tumor hypoxia: unfolded protein response (UPR)-dependent and UPR-independent pathways. Mol. Cancer Res. 4:423-436.
    • (2006) Mol. Cancer Res , vol.4 , pp. 423-436
    • Koumenis, C.1    Wouters, B.G.2
  • 20
    • 33947213491 scopus 로고    scopus 로고
    • Post-translational palmitoylation and glycosylation of Wnt-5a are necessary for its signalling
    • Kurayoshi, M., H. Yamamoto, S. Izumi, and A. Kikuchi. 2007. Post-translational palmitoylation and glycosylation of Wnt-5a are necessary for its signalling. Biochem. J. 402:515-523.
    • (2007) Biochem. J , vol.402 , pp. 515-523
    • Kurayoshi, M.1    Yamamoto, H.2    Izumi, S.3    Kikuchi, A.4
  • 21
    • 8444251784 scopus 로고    scopus 로고
    • The Wnt signaling pathway in development and disease
    • Logan, C. Y., and R. Nusse. 2004. The Wnt signaling pathway in development and disease. Annu. Rev. Cell Dev. Biol. 20:781-810.
    • (2004) Annu. Rev. Cell Dev. Biol , vol.20 , pp. 781-810
    • Logan, C.Y.1    Nusse, R.2
  • 22
    • 0027097821 scopus 로고
    • Mutational analysis of mouse Wnt-1 identifies two temperature-sensitive alleles and attributes of Wnt-1 protein essential for transformation of a mammary cell line
    • Mason, J. O., J. Kitajewski, and H. E. Varmus. 1992. Mutational analysis of mouse Wnt-1 identifies two temperature-sensitive alleles and attributes of Wnt-1 protein essential for transformation of a mammary cell line. Mol. Biol. Cell 3:521-533.
    • (1992) Mol. Biol. Cell , vol.3 , pp. 521-533
    • Mason, J.O.1    Kitajewski, J.2    Varmus, H.E.3
  • 23
    • 13944276380 scopus 로고    scopus 로고
    • Ero1-L alpha plays a key role in a HIF-1-mediated pathway to improve disulfide bond formation and VEGF secretion under hypoxia: Implication for cancer
    • May, D., A. Itin, O. Gal, H. Kalinski, E. Feinstein, and E. Keshet. 2005. Ero1-L alpha plays a key role in a HIF-1-mediated pathway to improve disulfide bond formation and VEGF secretion under hypoxia: implication for cancer. Oncogene 24:1011-1020.
    • (2005) Oncogene , vol.24 , pp. 1011-1020
    • May, D.1    Itin, A.2    Gal, O.3    Kalinski, H.4    Feinstein, E.5    Keshet, E.6
  • 24
    • 24044490922 scopus 로고    scopus 로고
    • Inhibition of Wnt16 in human acute lymphoblastoid leukemia cells containing the t(1;19) translocation induces apoptosis
    • Mazieres, J., L. You, B. He, Z. Xu, A. Y. Lee, I. Mikami, F. McCormick, and D. M. Jablons. 2005. Inhibition of Wnt16 in human acute lymphoblastoid leukemia cells containing the t(1;19) translocation induces apoptosis. Oncogene 24:5396-5400.
    • (2005) Oncogene , vol.24 , pp. 5396-5400
    • Mazieres, J.1    You, L.2    He, B.3    Xu, Z.4    Lee, A.Y.5    Mikami, I.6    McCormick, F.7    Jablons, D.M.8
  • 25
    • 33845352082 scopus 로고    scopus 로고
    • Wnts as ligands: Processing, secretion, and reception
    • Mikels, A. J., and R. Nusse. 2006. Wnts as ligands: processing, secretion, and reception. Oncogene 25:7461-7468.
    • (2006) Oncogene , vol.25 , pp. 7461-7468
    • Mikels, A.J.1    Nusse, R.2
  • 26
    • 33644622570 scopus 로고    scopus 로고
    • HIF-1 mediates adaptation to hypoxia by actively downregulating mitochondrial oxygen consumption
    • Papandreou, I., R. A. Cairns, L. Fontana, A. L. Lim, and N. C. Denko. 2006. HIF-1 mediates adaptation to hypoxia by actively downregulating mitochondrial oxygen consumption. Cell Metab. 3:187-197.
    • (2006) Cell Metab , vol.3 , pp. 187-197
    • Papandreou, I.1    Cairns, R.A.2    Fontana, L.3    Lim, A.L.4    Denko, N.C.5
  • 27
    • 17144416875 scopus 로고    scopus 로고
    • Anoxia is necessary for tumor cell toxicity caused by a low-oxygen environment
    • Papandreou, I., C. Krishna, F. Kaper, D. Cai, A. J. Giaccia, and N. C. Denko. 2005. Anoxia is necessary for tumor cell toxicity caused by a low-oxygen environment. Cancer Res. 65:3171-3178.
    • (2005) Cancer Res , vol.65 , pp. 3171-3178
    • Papandreou, I.1    Krishna, C.2    Kaper, F.3    Cai, D.4    Giaccia, A.J.5    Denko, N.C.6
  • 28
    • 33644502519 scopus 로고    scopus 로고
    • Telomere position effect and silencing of transgenes near telomeres in the mouse
    • Pedram, M., C. N. Sprung, Q. Gao, A. W. Lo, G. E. Reynolds, and J. P. Murnane. 2006. Telomere position effect and silencing of transgenes near telomeres in the mouse. Mol. Cell. Biol. 26:1865-1878.
    • (2006) Mol. Cell. Biol , vol.26 , pp. 1865-1878
    • Pedram, M.1    Sprung, C.N.2    Gao, Q.3    Lo, A.W.4    Reynolds, G.E.5    Murnane, J.P.6
  • 29
    • 0033895709 scopus 로고    scopus 로고
    • Wnt signaling and cancer
    • Polakis, P. 2000. Wnt signaling and cancer. Genes Dev. 14:1837-1851.
    • (2000) Genes Dev , vol.14 , pp. 1837-1851
    • Polakis, P.1
  • 31
    • 0037470064 scopus 로고    scopus 로고
    • Reduction-reoxidation cycles contribute to catalysis of disulfide isomerization by protein-disulfide isomerase
    • Schwaller, M., B. Wilkinson, and H. F. Gilbert. 2003. Reduction-reoxidation cycles contribute to catalysis of disulfide isomerization by protein-disulfide isomerase. J. Biol. Chem. 278:7154-7159.
    • (2003) J. Biol. Chem , vol.278 , pp. 7154-7159
    • Schwaller, M.1    Wilkinson, B.2    Gilbert, H.F.3
  • 34
    • 0034711439 scopus 로고    scopus 로고
    • Biochemical basis of oxidative protein folding in the endoplasmic reticulum
    • Tu, B. P., S. C. Ho-Schleyer, K. J. Travers, and J. S. Weissman. 2000. Biochemical basis of oxidative protein folding in the endoplasmic reticulum. Science 290:1571-1574.
    • (2000) Science , vol.290 , pp. 1571-1574
    • Tu, B.P.1    Ho-Schleyer, S.C.2    Travers, K.J.3    Weissman, J.S.4
  • 35
    • 0036862532 scopus 로고    scopus 로고
    • The FAD- and O(2)-dependent reaction cycle of Ero1-mediated oxidative protein folding in the endoplasmic reticulum
    • Tu, B. P., and J. S. Weissman. 2002. The FAD- and O(2)-dependent reaction cycle of Ero1-mediated oxidative protein folding in the endoplasmic reticulum. Mol. Cell 10:983-994.
    • (2002) Mol. Cell , vol.10 , pp. 983-994
    • Tu, B.P.1    Weissman, J.S.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.