Hypoxia activates the hedgehog signaling pathway in a ligand-independent manner by upregulation of Smo transcription in pancreatic cancer

Cancer Science

Volumn 102, Issue 6, 2011, Pages 1144-1150

  Onishi, Hideya ^a   Kai, Masaya ^a   Odate, Seiichi ^a   Iwasaki, Hironori ^a   Morifuji, Yoshihiro ^a   Ogino, Toshitatsu ^a   Morisaki, Takafumi ^a   Nakashima, Yutaka ^b   Katano, Mitsuo ^a  

^a KYUSHU UNIVERSITY   (Japan)

^b FUKUOKA RED CROSS HOSPITAL   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

GELATINASE B; SMOOTHENED PROTEIN; SONIC HEDGEHOG PROTEIN; TRANSCRIPTION FACTOR GLI1;

ARTICLE; CANCER INVASION; GENE SILENCING; GENETIC TRANSCRIPTION; HUMAN; HUMAN CELL; HYPOXIA; PANCREAS ISLET CELL CARCINOMA; PANCREATIC DUCTAL ADENOCARCINOMA CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; SIGNAL TRANSDUCTION; UPREGULATION;

CARCINOMA, PANCREATIC DUCTAL; CELL HYPOXIA; CELL LINE, TUMOR; GENE EXPRESSION REGULATION, NEOPLASTIC; HEDGEHOG PROTEINS; HUMANS; IMMUNOBLOTTING; LIGANDS; MATRIX METALLOPROTEINASE 9; NEOPLASM INVASIVENESS; PANCREATIC NEOPLASMS; POLYMERASE CHAIN REACTION; RECEPTORS, G-PROTEIN-COUPLED; RNA INTERFERENCE; RNA, SMALL INTERFERING; SIGNAL TRANSDUCTION; TRANSCRIPTION FACTORS; TRANSCRIPTION, GENETIC; TUMOR MICROENVIRONMENT;

EID: 79956219871     PISSN: 13479032     EISSN: 13497006     Source Type: Journal    
DOI: 10.1111/j.1349-7006.2011.01912.x     Document Type: Article

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