메뉴 건너뛰기




Volumn 68, Issue 13, 2008, Pages 5177-5184

Hypoxia-inducible factor-1α obstructs a wnt signaling pathway by inhibiting the hARD1-mediated activation of β-catenin

Author keywords

[No Author keywords available]

Indexed keywords

ACYLTRANSFERASE; AMIDE; BETA CATENIN; CYCLIN DEPENDENT KINASE INHIBITOR 1; HUMAN ARREST DEFECTIVE 1 PROTEIN; HYPOXIA INDUCIBLE FACTOR 1ALPHA; LITHIUM CHLORIDE; UNCLASSIFIED DRUG; WNT1 PROTEIN; ARD1A PROTEIN, HUMAN; HIF1A PROTEIN, HUMAN; MYC PROTEIN; MYC PROTEIN, HUMAN; PROTEIN P21; T CELL FACTOR 4; T CELL FACTOR PROTEIN; WNT PROTEIN;

EID: 48549098557     PISSN: 00085472     EISSN: None     Source Type: Journal    
DOI: 10.1158/0008-5472.CAN-07-6234     Document Type: Article
Times cited : (88)

References (48)
  • 1
    • 0035925098 scopus 로고    scopus 로고
    • Tumor hypoxia: Definitions and current clinical, biologic, and molecular aspects
    • Hockel M, Vaupel P. Tumor hypoxia: definitions and current clinical, biologic, and molecular aspects. J Natl Cancer Inst 2001;93:266-76.
    • (2001) J Natl Cancer Inst , vol.93 , pp. 266-276
    • Hockel, M.1    Vaupel, P.2
  • 2
    • 0029753768 scopus 로고    scopus 로고
    • Genetic instability induced by the tumor microenvironment
    • Reynolds TY, Rockwell S, Glazer PM. Genetic instability induced by the tumor microenvironment. Cancer Res 1996;56:5754-7.
    • (1996) Cancer Res , vol.56 , pp. 5754-5757
    • Reynolds, T.Y.1    Rockwell, S.2    Glazer, P.M.3
  • 3
    • 0034743861 scopus 로고    scopus 로고
    • Oxygen status of malignant tumors: Pathogenesis of hypoxia and significance for tumor therapy
    • Vaupel P, Kelleher DK, Hockel M. Oxygen status of malignant tumors: pathogenesis of hypoxia and significance for tumor therapy. Semin Oncol 2001;28:29-35.
    • (2001) Semin Oncol , vol.28 , pp. 29-35
    • Vaupel, P.1    Kelleher, D.K.2    Hockel, M.3
  • 4
    • 0036359548 scopus 로고    scopus 로고
    • Hypoxia-a key regulatory factor in tumour growth
    • Harris AL. Hypoxia-a key regulatory factor in tumour growth. Nat Rev Cancer 2002;2:38-47.
    • (2002) Nat Rev Cancer , vol.2 , pp. 38-47
    • Harris, A.L.1
  • 5
    • 0142166332 scopus 로고    scopus 로고
    • Targeting HIF-1 for cancer therapy
    • Semenza GL. Targeting HIF-1 for cancer therapy. Nat Rev Cancer 2002;3:721-32.
    • (2002) Nat Rev Cancer , vol.3 , pp. 721-732
    • Semenza, G.L.1
  • 7
    • 8544271638 scopus 로고    scopus 로고
    • Hypoxia-inducible factors and hypoxic cell death in tumour physiology
    • Bacon AL, Harris AL. Hypoxia-inducible factors and hypoxic cell death in tumour physiology. Ann Med 2004;36:530-9.
    • (2004) Ann Med , vol.36 , pp. 530-539
    • Bacon, A.L.1    Harris, A.L.2
  • 8
    • 0028816847 scopus 로고
    • Purification and characterization of hypoxia-inducible factor 1
    • Wang GL, Semenza GL. Purification and characterization of hypoxia-inducible factor 1. J Biol Chem 1995;270:1230-7.
    • (1995) J Biol Chem , vol.270 , pp. 1230-1237
    • Wang, G.L.1    Semenza, G.L.2
  • 9
    • 17944375360 scopus 로고    scopus 로고
    • Epstein AC, Gleadle JM, McNeill LA, et al. C. elegans EGL-9 and mammalian homologs define a family of dioxygenases that regulate HIF by prolyl hydroxylation. Cell 2001;107:43-54.
    • Epstein AC, Gleadle JM, McNeill LA, et al. C. elegans EGL-9 and mammalian homologs define a family of dioxygenases that regulate HIF by prolyl hydroxylation. Cell 2001;107:43-54.
  • 10
    • 0035903468 scopus 로고    scopus 로고
    • Independent function of two destruction domains in hypoxia-inducible factor-α chains activated by prolyl hydroxylation
    • Masson N, Willam C, Maxwell PH, Pugh CW, Ratcliffe PJ. Independent function of two destruction domains in hypoxia-inducible factor-α chains activated by prolyl hydroxylation. EMBO J 2001;20:5197-206.
    • (2001) EMBO J , vol.20 , pp. 5197-5206
    • Masson, N.1    Willam, C.2    Maxwell, P.H.3    Pugh, C.W.4    Ratcliffe, P.J.5
  • 11
    • 0033587146 scopus 로고    scopus 로고
    • The tumour suppressor protein VHL targets hypoxia-inducible factors for oxygen-dependent proteolysis
    • Maxwell PH, Wiesener MS, Chang GW, et al. The tumour suppressor protein VHL targets hypoxia-inducible factors for oxygen-dependent proteolysis. Nature 1999;399:271-5.
    • (1999) Nature , vol.399 , pp. 271-275
    • Maxwell, P.H.1    Wiesener, M.S.2    Chang, G.W.3
  • 13
    • 18744375998 scopus 로고    scopus 로고
    • Regulation and destabilization of HIF-1α by ARD1-mediated acetylation
    • Jeong JW, Bae MK, Ahn MY, et al. Regulation and destabilization of HIF-1α by ARD1-mediated acetylation. Cell 2002;111:709-20.
    • (2002) Cell , vol.111 , pp. 709-720
    • Jeong, J.W.1    Bae, M.K.2    Ahn, M.Y.3
  • 14
    • 0037097861 scopus 로고    scopus 로고
    • FIH-1 is an asparaginyl hydroxylase enzyme that regulates the transcriptional activity of hypoxia-inducible factor
    • Lando D, Peet DJ, Gorman JJ, Whelan DA, Whitelaw ML, Bruick RK. FIH-1 is an asparaginyl hydroxylase enzyme that regulates the transcriptional activity of hypoxia-inducible factor. Genes Dev 2002;16:1466-71.
    • (2002) Genes Dev , vol.16 , pp. 1466-1471
    • Lando, D.1    Peet, D.J.2    Gorman, J.J.3    Whelan, D.A.4    Whitelaw, M.L.5    Bruick, R.K.6
  • 15
    • 0031888098 scopus 로고    scopus 로고
    • β-Catenin: A key mediator of Wnt signaling
    • Willert K, Nusse R. β-Catenin: a key mediator of Wnt signaling. Curr Opin Genet Dev 1998;8:95-102.
    • (1998) Curr Opin Genet Dev , vol.8 , pp. 95-102
    • Willert, K.1    Nusse, R.2
  • 16
    • 33744791463 scopus 로고    scopus 로고
    • Wnt signaling: Is the party in the nucleus?
    • Willert K, Jones KA. Wnt signaling: is the party in the nucleus? Genes Dev 2006;20:1394-404.
    • (2006) Genes Dev , vol.20 , pp. 1394-1404
    • Willert, K.1    Jones, K.A.2
  • 17
    • 35648949978 scopus 로고    scopus 로고
    • β-Catenin signaling in biological control and cancer
    • Gavert N, Ben-Ze'ev A. β-Catenin signaling in biological control and cancer. J Cell Biochem 2007;102:820-8.
    • (2007) J Cell Biochem , vol.102 , pp. 820-828
    • Gavert, N.1    Ben-Ze'ev, A.2
  • 18
    • 33846193290 scopus 로고    scopus 로고
    • The many ways of Wnt in cancer
    • Polakis P. The many ways of Wnt in cancer. Curr Opin Genet Dev 2007;17:45-51.
    • (2007) Curr Opin Genet Dev , vol.17 , pp. 45-51
    • Polakis, P.1
  • 19
    • 33947217823 scopus 로고    scopus 로고
    • Interaction between β-catenin and HIF-1 promotes cellular adaptation to hypoxia
    • Kaidi A, Williams AC, Paraskeva C. Interaction between β-catenin and HIF-1 promotes cellular adaptation to hypoxia. Nat Cell Biol 2007;9:210-7.
    • (2007) Nat Cell Biol , vol.9 , pp. 210-217
    • Kaidi, A.1    Williams, A.C.2    Paraskeva, C.3
  • 20
    • 0022407123 scopus 로고
    • The ARD1 gene of yeast functions in the switch between the mitotic cell cycle and alternative developmental pathways
    • Whiteway M, Szostak JW. The ARD1 gene of yeast functions in the switch between the mitotic cell cycle and alternative developmental pathways. Cell 1985;43:483-92.
    • (1985) Cell , vol.43 , pp. 483-492
    • Whiteway, M.1    Szostak, J.W.2
  • 21
    • 0026605888 scopus 로고
    • ARD1 and NAT1 proteins form a complex that has N-terminal acetyltransferase activity
    • Park EC, Szostak JW. ARD1 and NAT1 proteins form a complex that has N-terminal acetyltransferase activity. EMBO J 1995;11:2087-93.
    • (1995) EMBO J , vol.11 , pp. 2087-2093
    • Park, E.C.1    Szostak, J.W.2
  • 22
    • 0141925607 scopus 로고    scopus 로고
    • An evolutionarily conserved N-terminal acetyltransferase complex associated with neuronal development
    • Sugiura N, Adams SM, Corriveau RA. An evolutionarily conserved N-terminal acetyltransferase complex associated with neuronal development. J Biol Chem 2003;278:40113-20.
    • (2003) J Biol Chem , vol.278 , pp. 40113-40120
    • Sugiura, N.1    Adams, S.M.2    Corriveau, R.A.3
  • 25
    • 29644438345 scopus 로고    scopus 로고
    • Characterization of ARD1 variants in mammalian cells
    • Kim SH, Park JA, Kim JH, et al. Characterization of ARD1 variants in mammalian cells. Biochem Biophys Res Commun 2006;340:422-7.
    • (2006) Biochem Biophys Res Commun , vol.340 , pp. 422-427
    • Kim, S.H.1    Park, J.A.2    Kim, J.H.3
  • 26
    • 33845663235 scopus 로고    scopus 로고
    • Differential regulation of splicing, localization and stability of mammalian ARD1235 and ARD1225 isoforms
    • Chun KH, Cho SJ, Choi JS, Kim SH, Kim KW, Lee SK. Differential regulation of splicing, localization and stability of mammalian ARD1235 and ARD1225 isoforms. Biochem Biophys Res Commun 2007;353:18-25.
    • (2007) Biochem Biophys Res Commun , vol.353 , pp. 18-25
    • Chun, K.H.1    Cho, S.J.2    Choi, J.S.3    Kim, S.H.4    Kim, K.W.5    Lee, S.K.6
  • 27
    • 27744450043 scopus 로고    scopus 로고
    • Interaction between HIF-1 a (ODD) and hARD1 does not induce acetylation and destabilization of HIF-1 α
    • Arnesen T, Kong X, Evjenth R, et al. Interaction between HIF-1 a (ODD) and hARD1 does not induce acetylation and destabilization of HIF-1 α. FEBS Lett 2005;579:6428-32.
    • (2005) FEBS Lett , vol.579 , pp. 6428-6432
    • Arnesen, T.1    Kong, X.2    Evjenth, R.3
  • 28
    • 33845293454 scopus 로고    scopus 로고
    • Human arrest defective 1 acetylates and activates β-catenin, promoting lung cancer cell proliferation
    • Lim JH, Park JW, Chun YS. Human arrest defective 1 acetylates and activates β-catenin, promoting lung cancer cell proliferation. Cancer Res 2006;66:10677-82.
    • (2006) Cancer Res , vol.66 , pp. 10677-10682
    • Lim, J.H.1    Park, J.W.2    Chun, Y.S.3
  • 31
    • 0035205085 scopus 로고    scopus 로고
    • A new HIF-1 α variant induced by zinc ion suppresses HIF-1-mediated hypoxic responses
    • Chun YS, Choi E, Yeo EJ, Lee JH, Kim MS, Park JW. A new HIF-1 α variant induced by zinc ion suppresses HIF-1-mediated hypoxic responses. J Cell Sci 2001;114:4051-61.
    • (2001) J Cell Sci , vol.114 , pp. 4051-4061
    • Chun, Y.S.1    Choi, E.2    Yeo, E.J.3    Lee, J.H.4    Kim, M.S.5    Park, J.W.6
  • 32
    • 0346059588 scopus 로고    scopus 로고
    • Phorbol ester stimulates the nonhypoxic induction of a novel hypoxia-inducible factor 1α isoform: Implications for tumor promotion
    • Chun YS, Lee KH, Choi E, et al. Phorbol ester stimulates the nonhypoxic induction of a novel hypoxia-inducible factor 1α isoform: implications for tumor promotion. Cancer Res 2003;63:8700-7.
    • (2003) Cancer Res , vol.63 , pp. 8700-8707
    • Chun, Y.S.1    Lee, K.H.2    Choi, E.3
  • 33
    • 27944445890 scopus 로고    scopus 로고
    • Differential responses of two degradation domains of HIF-1α to hypoxia and iron deficiency
    • Lee KH, Choi E, Chun YS, Kim MS, Park JW. Differential responses of two degradation domains of HIF-1α to hypoxia and iron deficiency. Biochimie 2006;88:163-9.
    • (2006) Biochimie , vol.88 , pp. 163-169
    • Lee, K.H.1    Choi, E.2    Chun, Y.S.3    Kim, M.S.4    Park, J.W.5
  • 34
    • 33846990665 scopus 로고    scopus 로고
    • A domain responsible for HIF-1α degradation by YC-1, a novel anticancer agent
    • Kim HL, Yeo EJ, Chun YS, Park JW. A domain responsible for HIF-1α degradation by YC-1, a novel anticancer agent. Int J Oncol 2006;29:255-60.
    • (2006) Int J Oncol , vol.29 , pp. 255-260
    • Kim, H.L.1    Yeo, E.J.2    Chun, Y.S.3    Park, J.W.4
  • 35
    • 18644373146 scopus 로고    scopus 로고
    • The β-catenin/TCF-4 complex imposes a crypt progenitor phenotype on colorectal cancer cells
    • van de Wetering M, Sancho E, Verweij C, et al. The β-catenin/TCF-4 complex imposes a crypt progenitor phenotype on colorectal cancer cells. Cell 2002;111:241-50.
    • (2002) Cell , vol.111 , pp. 241-250
    • van de Wetering, M.1    Sancho, E.2    Verweij, C.3
  • 36
    • 20144384882 scopus 로고    scopus 로고
    • Gartel AL, Radhakrishnan SK. Lost in transcription: p21 repression, mechanisms, and consequences. Cancer Res 2005;65:3980-5.
    • Gartel AL, Radhakrishnan SK. Lost in transcription: p21 repression, mechanisms, and consequences. Cancer Res 2005;65:3980-5.
  • 37
    • 16844379943 scopus 로고    scopus 로고
    • Hypoxia and anemia: Effects on tumor biology and treatment resistance
    • Vaupel P, Mayer A. Hypoxia and anemia: effects on tumor biology and treatment resistance. Transfus Clin Biol 2005;12:5-10.
    • (2005) Transfus Clin Biol , vol.12 , pp. 5-10
    • Vaupel, P.1    Mayer, A.2
  • 38
    • 23144464363 scopus 로고    scopus 로고
    • Transcriptional regulation and transformation by Myc proteins
    • Adhikary S, Eilers M. Transcriptional regulation and transformation by Myc proteins. Nat Rev Mol Cell Biol 2005;6:635-45.
    • (2005) Nat Rev Mol Cell Biol , vol.6 , pp. 635-645
    • Adhikary, S.1    Eilers, M.2
  • 39
    • 0037330625 scopus 로고    scopus 로고
    • Mechanisms of c-myc-mediated transcriptional repression of growth arrest genes
    • Gartel AL, Shchors K. Mechanisms of c-myc-mediated transcriptional repression of growth arrest genes. Exp Cell Res 2003;283:17-21.
    • (2003) Exp Cell Res , vol.283 , pp. 17-21
    • Gartel, A.L.1    Shchors, K.2
  • 40
    • 11144353713 scopus 로고    scopus 로고
    • Acetylation of β-catenin by p300 regulates β-catenin-Tcf4 interaction
    • Levy L, Wei Y, Labalette C, et al. Acetylation of β-catenin by p300 regulates β-catenin-Tcf4 interaction. Mol Cell Biol 2004;24:3404-14.
    • (2004) Mol Cell Biol , vol.24 , pp. 3404-3414
    • Levy, L.1    Wei, Y.2    Labalette, C.3
  • 41
    • 0033870727 scopus 로고    scopus 로고
    • Hypoxia-inducible factor-1α is a positive factor in solid tumor growth
    • Ryan HE, Poloni M, McNulty W, et al. Hypoxia-inducible factor-1α is a positive factor in solid tumor growth. Cancer Res 2000;60:4010-5.
    • (2000) Cancer Res , vol.60 , pp. 4010-4015
    • Ryan, H.E.1    Poloni, M.2    McNulty, W.3
  • 42
    • 0037414180 scopus 로고    scopus 로고
    • YC-1: A potential anticancer drug targeting hypoxia-inducible factor 1
    • Yeo EJ, Chun YS, Cho YS, et al. YC-1: a potential anticancer drug targeting hypoxia-inducible factor 1. J Natl Cancer Inst 2003;95:516-25.
    • (2003) J Natl Cancer Inst , vol.95 , pp. 516-525
    • Yeo, E.J.1    Chun, Y.S.2    Cho, Y.S.3
  • 43
    • 0032581277 scopus 로고    scopus 로고
    • Role of HIF-1α in hypoxia-mediated apoptosis, cell proliferation and tumour angiogenesis
    • Carmeliet P, Dor Y, Herbert JM, et al. Role of HIF-1α in hypoxia-mediated apoptosis, cell proliferation and tumour angiogenesis. Nature 1998;394:485-90.
    • (1998) Nature , vol.394 , pp. 485-490
    • Carmeliet, P.1    Dor, Y.2    Herbert, J.M.3
  • 44
    • 0038383678 scopus 로고    scopus 로고
    • Loss of pVHL is sufficient to cause HIF dysregulation in primary cells but does not promote tumor growth
    • Mack FA, Rathmell WK, Arsham AM, Gnarra J, Keith B, Simon MC. Loss of pVHL is sufficient to cause HIF dysregulation in primary cells but does not promote tumor growth. Cancer Cell 2003;3:75-88.
    • (2003) Cancer Cell , vol.3 , pp. 75-88
    • Mack, F.A.1    Rathmell, W.K.2    Arsham, A.M.3    Gnarra, J.4    Keith, B.5    Simon, M.C.6
  • 45
    • 33751072389 scopus 로고    scopus 로고
    • Bafilomycin induces the p21-mediated growth inhibition of cancer cells under hypoxic conditions by expressing hypoxia-inducible factor-1α
    • Lim JH, Park JW, Kim MS, Park SK, Johnson RS, Chun YS. Bafilomycin induces the p21-mediated growth inhibition of cancer cells under hypoxic conditions by expressing hypoxia-inducible factor-1α. Mol Pharmacol 2006;70:1856-65.
    • (2006) Mol Pharmacol , vol.70 , pp. 1856-1865
    • Lim, J.H.1    Park, J.W.2    Kim, M.S.3    Park, S.K.4    Johnson, R.S.5    Chun, Y.S.6
  • 46
    • 33847751015 scopus 로고    scopus 로고
    • Suppression of the hypoxia-inducible factor-1 response in cervical carcinoma xenografts by proteasome inhibitors
    • Birle DC, Hedley DW. Suppression of the hypoxia-inducible factor-1 response in cervical carcinoma xenografts by proteasome inhibitors. Cancer Res 2007;67:1735-43.
    • (2007) Cancer Res , vol.67 , pp. 1735-1743
    • Birle, D.C.1    Hedley, D.W.2
  • 48
    • 33744971921 scopus 로고    scopus 로고
    • Induction of apoptosis in human cells by RNAi-mediated knockdown of hARD1 and NATH, components of the protein N-α-acetyltransferase complex
    • Arnesen T, Gromyko D, Pendino F, Ryningen A, Varhaug JE, Lillehaug JR. Induction of apoptosis in human cells by RNAi-mediated knockdown of hARD1 and NATH, components of the protein N-α-acetyltransferase complex. Oncogene 2006;25:4350-60.
    • (2006) Oncogene , vol.25 , pp. 4350-4360
    • Arnesen, T.1    Gromyko, D.2    Pendino, F.3    Ryningen, A.4    Varhaug, J.E.5    Lillehaug, J.R.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.