-
1
-
-
0030738644
-
Blood pressure response to chronic episodic hypoxia: Role of the sympathetic nervous system
-
Bao G, Metreveli N, Li R, Taylor A, Fletcher EC. 1997. Blood pressure response to chronic episodic hypoxia: Role of the sympathetic nervous system. J Appl Physiol 83: 95-101.
-
(1997)
J Appl Physiol
, vol.83
, pp. 95-101
-
-
Bao, G.1
Metreveli, N.2
Li, R.3
Taylor, A.4
Fletcher, E.C.5
-
2
-
-
33846794822
-
The NOX family of ROS-generating NADPH oxidases: Physiology and pathophysiology
-
Bedard K, Krause KH. 2007. The NOX family of ROS-generating NADPH oxidases: Physiology and pathophysiology. Physiol Rev 87: 245-313.
-
(2007)
Physiol Rev
, vol.87
, pp. 245-313
-
-
Bedard, K.1
Krause, K.H.2
-
3
-
-
70349478990
-
MicroRNA-210 controls mitochondrial metabolism during hypoxia by repressing the iron-sulfur cluster assembly proteins ISCU1/2
-
Chan SY, Zhang YY, Hemann C, Mahoney CE, Zweier JL, Loscalzo J. 2009. MicroRNA-210 controls mitochondrial metabolism during hypoxia by repressing the iron-sulfur cluster assembly proteins ISCU1/2. Cell Metab 10: 273-284.
-
(2009)
Cell Metab
, vol.10
, pp. 273-284
-
-
Chan, S.Y.1
Zhang, Y.Y.2
Hemann, C.3
Mahoney, C.E.4
Zweier, J.L.5
Loscalzo, J.6
-
4
-
-
77955170881
-
Hypoxia-regulated microRNA-210 modulates mitochondrial function and decreases ISCU and COX10 expression
-
Chen Z, Li Y, Zhang H, Huang P, Luthra R. 2010. Hypoxia-regulated microRNA-210 modulates mitochondrial function and decreases ISCU and COX10 expression. Oncogene 29: 4362-4368.
-
(2010)
Oncogene
, vol.29
, pp. 4362-4368
-
-
Chen, Z.1
Li, Y.2
Zhang, H.3
Huang, P.4
Luthra, R.5
-
5
-
-
77954649706
-
Carotid body and cardiorespiratory alterations in intermittent hypoxia: The oxidative link
-
Del Rio R, Moya EA, Iturriaga R. 2010. Carotid body and cardiorespiratory alterations in intermittent hypoxia: The oxidative link. Eur Respir J 36: 143-150.
-
(2010)
Eur Respir J
, vol.36
, pp. 143-150
-
-
Del Rio, R.1
Moya, E.A.2
Iturriaga, R.3
-
6
-
-
77956402239
-
MicroRNA-210 regulates mitochondrial free radical response to hypoxia and Krebs cycle in cancer cells by targeting iron sulfur cluster protein ISCU
-
Favaro E, Ramachandran A, McCormick R, Gee H, Blancher C, Crosby M, Devlin C, Blick C, Buffa F, Li JL, Vojnovic B, Pires das Neves R, Glazer P, Iborra F, Ivan M, Ragoussis J, Harris AL. 2010. MicroRNA-210 regulates mitochondrial free radical response to hypoxia and Krebs cycle in cancer cells by targeting iron sulfur cluster protein ISCU. PLoS ONE 5: e10345.
-
(2010)
PLoS ONE
, vol.5
-
-
Favaro, E.1
Ramachandran, A.2
McCormick, R.3
Gee, H.4
Blancher, C.5
Crosby, M.6
Devlin, C.7
Blick, C.8
Buffa, F.9
Li, J.L.10
Vojnovic, B.11
Pires das Neves, R.12
Glazer, P.13
Iborra, F.14
Ivan, M.15
Ragoussis, J.16
Harris, A.L.17
-
7
-
-
0033566693
-
Reciprocal positive regulation of hypoxia-inducible factor 1alpha and insulin-like growth factor 2
-
Feldser D, Agani F, Iyer NV, Pak B, Ferreira G, Semenza GL. 1999. Reciprocal positive regulation of hypoxia-inducible factor 1alpha and insulin-like growth factor 2. Cancer Res 59: 3915-3918.
-
(1999)
Cancer Res
, vol.59
, pp. 3915-3918
-
-
Feldser, D.1
Agani, F.2
Iyer, N.V.3
Pak, B.4
Ferreira, G.5
Semenza, G.L.6
-
8
-
-
0026602427
-
Repetitive, episodic hypoxia causes diurnal elevation of blood pressure in rats
-
Fletcher EC, Lesske J, Qian W, Miller CC III, Unger T. 1992. Repetitive, episodic hypoxia causes diurnal elevation of blood pressure in rats. Hypertension 19: 555-561.
-
(1992)
Hypertension
, vol.19
, pp. 555-561
-
-
Fletcher, E.C.1
Lesske, J.2
Qian, W.3
Miller III, C.C.4
Unger, T.5
-
9
-
-
33947724515
-
HIF-1 regulates cytochrome oxidase subunits to optimize efficiency of respiration in hypoxic cells
-
Fukuda R, Zhang H, Kim JW, Shimoda L, Dang CV, Semenza GL. 2007. HIF-1 regulates cytochrome oxidase subunits to optimize efficiency of respiration in hypoxic cells. Cell 129: 111-122.
-
(2007)
Cell
, vol.129
, pp. 111-122
-
-
Fukuda, R.1
Zhang, H.2
Kim, J.W.3
Shimoda, L.4
Dang, C.V.5
Semenza, G.L.6
-
10
-
-
15444342958
-
2 homeostasis by hypoxia-inducible factor 1a
-
2 homeostasis by hypoxia-inducible factor 1a. Genes Dev 12: 149-162.
-
(1998)
Genes Dev
, vol.12
, pp. 149-162
-
-
Iyer, N.V.1
Kotch, L.E.2
Agani, F.3
Leung, S.W.4
Laughner, E.5
Wenger, R.H.6
Gassmann, M.7
Gearhart, J.D.8
Lawler, A.M.9
Yu, A.Y.10
Semenza, G.L.11
-
11
-
-
79251546780
-
Nox2 mediates intermittent hypoxia-induced mitochondrial complex I inhibition: Relevance to blood pressure changes in rats
-
Khan S, Nanduri J, Yuan G, Kinsman B, Kumar GK, Joseph J, Kalyanaraman B, Prabhakar NR. 2010. Nox2 mediates intermittent hypoxia-induced mitochondrial complex I inhibition: Relevance to blood pressure changes in rats. Antioxid Redox Signal 14: 533-542.
-
(2010)
Antioxid Redox Signal
, vol.14
, pp. 533-542
-
-
Khan, S.1
Nanduri, J.2
Yuan, G.3
Kinsman, B.4
Kumar, G.K.5
Joseph, J.6
Kalyanaraman, B.7
Prabhakar, N.R.8
-
12
-
-
33644614520
-
HIF-1-mediated expression of pyruvate dehydrogenase kinase: A metabolic switch required for cellular adaptation to hypoxia
-
Kim JW, Tchernyshyov I, Semenza GL, Dang CV. 2006. HIF-1-mediated expression of pyruvate dehydrogenase kinase: A metabolic switch required for cellular adaptation to hypoxia. Cell Metab 3: 177-185.
-
(2006)
Cell Metab
, vol.3
, pp. 177-185
-
-
Kim, J.W.1
Tchernyshyov, I.2
Semenza, G.L.3
Dang, C.V.4
-
13
-
-
33746847626
-
Chronic intermittent hypoxia induces hypoxia-evoked catecholamine efflux in adult rat adrenal medulla via oxidative stress
-
Kumar GK, Rai V, Sharma SD, Ramakrishnan DP, Peng YJ, Souvannakitti D, Prabhakar NR. 2006. Chronic intermittent hypoxia induces hypoxia-evoked catecholamine efflux in adult rat adrenal medulla via oxidative stress. J Physiol 575: 229-239.
-
(2006)
J Physiol
, vol.575
, pp. 229-239
-
-
Kumar, G.K.1
Rai, V.2
Sharma, S.D.3
Ramakrishnan, D.P.4
Peng, Y.J.5
Souvannakitti, D.6
Prabhakar, N.R.7
-
14
-
-
34848915482
-
Increased secretory capacity of mouse adrenal chromaffin cells by chronic intermittent hypoxia: Involvement of protein kinase C
-
Kuri BA, Khan SA, Chan SA, Prabhakar NR, Smith CB. 2007. Increased secretory capacity of mouse adrenal chromaffin cells by chronic intermittent hypoxia: Involvement of protein kinase C. J Physiol 584: 313-319.
-
(2007)
J Physiol
, vol.584
, pp. 313-319
-
-
Kuri, B.A.1
Khan, S.A.2
Chan, S.A.3
Prabhakar, N.R.4
Smith, C.B.5
-
15
-
-
0037205457
-
Intracellular localization and preassembly of the NADPH oxidase complex in cultured endothelial cells
-
Li JM, Shah AM. 2002. Intracellular localization and preassembly of the NADPH oxidase complex in cultured endothelial cells. J Biol Chem 277: 19952-19960.
-
(2002)
J Biol Chem
, vol.277
, pp. 19952-19960
-
-
Li, J.M.1
Shah, A.M.2
-
16
-
-
0034956261
-
Phenotypic properties and characteristics of superoxide production by mouse coronary microvascular endothelial cells
-
Li JM, Mullen AM, Shah AM. 2001. Phenotypic properties and characteristics of superoxide production by mouse coronary microvascular endothelial cells. J Mol Cell Cardiol 33: 1119-1131.
-
(2001)
J Mol Cell Cardiol
, vol.33
, pp. 1119-1131
-
-
Li, J.M.1
Mullen, A.M.2
Shah, A.M.3
-
17
-
-
67650531089
-
Genome-wide association of hypoxia-inducible factor (HIF)-1a and HIF-2a DNA binding with expression profiling of hypoxia-inducible transcripts
-
Mole DR, Blancher C, Copley RR, Pollard PJ, Gleadle JM, Ragoussis J, Ratcliffe PJ. 2009. Genome-wide association of hypoxia-inducible factor (HIF)-1a and HIF-2a DNA binding with expression profiling of hypoxia-inducible transcripts. J Biol Chem 284: 16767-16775.
-
(2009)
J Biol Chem
, vol.284
, pp. 16767-16775
-
-
Mole, D.R.1
Blancher, C.2
Copley, R.R.3
Pollard, P.J.4
Gleadle, J.M.5
Ragoussis, J.6
Ratcliffe, P.J.7
-
18
-
-
59049086571
-
Intermittent hypoxia degrades HIF-2a via calpains resulting in oxidative stress: Implications for recurrent apnea-induced morbidities
-
Nanduri J, Wang N, Yuan G, Khan SA, Souvannakitti D, Peng YJ, Kumar GK, Garcia JA, Prabhakar NR. 2009. Intermittent hypoxia degrades HIF-2a via calpains resulting in oxidative stress: Implications for recurrent apnea-induced morbidities. Proc Natl Acad Sci USA 106: 1199-1204.
-
(2009)
Proc Natl Acad Sci USA
, vol.106
, pp. 1199-1204
-
-
Nanduri, J.1
Wang, N.2
Yuan, G.3
Khan, S.A.4
Souvannakitti, D.5
Peng, Y.J.6
Kumar, G.K.7
Garcia, J.A.8
Prabhakar, N.R.9
-
19
-
-
0031461027
-
The sympathetic nervous system and obstructive sleep apnea: Implications for hypertension
-
Narkiewicz K, Somers VK. 1997. The sympathetic nervous system and obstructive sleep apnea: Implications for hypertension. J Hypertens 15: 1613-1619.
-
(1997)
J Hypertens
, vol.15
, pp. 1613-1619
-
-
Narkiewicz, K.1
Somers, V.K.2
-
20
-
-
0343362699
-
Association of sleep-disordered breathing, sleep apnea, and hypertension in a large community-based study. Sleep Heart Health Study
-
Nieto FJ, Young TB, Lind BK, Shahar E, Samet JM, Redline S, D'Agostino RB, Newman AB, Lebowitz MD, Pickering TG. 2000. Association of sleep-disordered breathing, sleep apnea, and hypertension in a large community-based study. Sleep Heart Health Study. JAMA 283: 1829-1836.
-
(2000)
JAMA
, vol.283
, pp. 1829-1836
-
-
Nieto, F.J.1
Young, T.B.2
Lind, B.K.3
Shahar, E.4
Samet, J.M.5
Redline, S.6
D'Agostino, R.B.7
Newman, A.B.8
Lebowitz, M.D.9
Pickering, T.G.10
-
21
-
-
1342283025
-
Effect of two paradigms of chronic intermittent hypoxia on carotid body sensory activity
-
Peng YJ, Prabhakar NR. 2004. Effect of two paradigms of chronic intermittent hypoxia on carotid body sensory activity. J Appl Physiol 96: 1236-1242.
-
(2004)
J Appl Physiol
, vol.96
, pp. 1236-1242
-
-
Peng, Y.J.1
Prabhakar, N.R.2
-
22
-
-
0042691713
-
Induction of sensory long-term facilitation in the carotid body by intermittent hypoxia: Implications for recurrent apneas
-
Peng YJ, Overholt JL, Kline D, Kumar GK, Prabhakar NR. 2003. Induction of sensory long-term facilitation in the carotid body by intermittent hypoxia: Implications for recurrent apneas. Proc Natl Acad Sci USA 100: 10073-10078.
-
(2003)
Proc Natl Acad Sci USA
, vol.100
, pp. 10073-10078
-
-
Peng, Y.J.1
Overholt, J.L.2
Kline, D.3
Kumar, G.K.4
Prabhakar, N.R.5
-
23
-
-
33751329032
-
Heterozygous HIF-1a deficiency impairs carotid body-mediated systemic responses and reactive oxygen species generation in mice exposed to intermittent hypoxia
-
Peng YJ, Yuan G, Ramakrishnan D, Sharma SD, Bosch-Marce M, Kumar GK, Semenza GL, Prabhakar NR. 2006. Heterozygous HIF-1a deficiency impairs carotid body-mediated systemic responses and reactive oxygen species generation in mice exposed to intermittent hypoxia. J Physiol 577: 705-716.
-
(2006)
J Physiol
, vol.577
, pp. 705-716
-
-
Peng, Y.J.1
Yuan, G.2
Ramakrishnan, D.3
Sharma, S.D.4
Bosch-Marce, M.5
Kumar, G.K.6
Semenza, G.L.7
Prabhakar, N.R.8
-
24
-
-
65549160457
-
NADPH oxidase is required for the sensory plasticity of the carotid body by chronic intermittent hypoxia
-
Peng YJ, Nanduri J, Yuan G, Wang N, Deneris E, Pendyala S, Natarajan V, Kumar GK, Prabhakar NR. 2009. NADPH oxidase is required for the sensory plasticity of the carotid body by chronic intermittent hypoxia. J Neurosci 29: 4903-4910.
-
(2009)
J Neurosci
, vol.29
, pp. 4903-4910
-
-
Peng, Y.J.1
Nanduri, J.2
Yuan, G.3
Wang, N.4
Deneris, E.5
Pendyala, S.6
Natarajan, V.7
Kumar, G.K.8
Prabhakar, N.R.9
-
25
-
-
0034636477
-
Prospective study of the association between sleep-disordered breathing and hypertension
-
Peppard PE, Young T, Palta M, Skatrud J. 2000. Prospective study of the association between sleep-disordered breathing and hypertension. N Engl J Med 342: 1378-1384.
-
(2000)
N Engl J Med
, vol.342
, pp. 1378-1384
-
-
Peppard, P.E.1
Young, T.2
Palta, M.3
Skatrud, J.4
-
26
-
-
0028221842
-
Epidemiology and pathophysiology of apnoea of prematurity
-
Poets CF, Samuels MP, Southall DP. 1994. Epidemiology and pathophysiology of apnoea of prematurity. Biol Neonate 65: 211-219.
-
(1994)
Biol Neonate
, vol.65
, pp. 211-219
-
-
Poets, C.F.1
Samuels, M.P.2
Southall, D.P.3
-
27
-
-
78049387065
-
Mechanisms of sympathetic activation and blood pressure elevation by intermittent hypoxia
-
Prabhakar NR, Kumar GK. 2010. Mechanisms of sympathetic activation and blood pressure elevation by intermittent hypoxia. Respir Physiol Neurobiol 174: 156-161.
-
(2010)
Respir Physiol Neurobiol
, vol.174
, pp. 156-161
-
-
Prabhakar, N.R.1
Kumar, G.K.2
-
28
-
-
85047682984
-
Regulation of oxygen homeostasis by hypoxia-inducible factor 1
-
Semenza GL. 2009. Regulation of oxygen homeostasis by hypoxia-inducible factor 1. Physiology (Bethesda) 24: 97-106.
-
(2009)
Physiology (Bethesda)
, vol.24
, pp. 97-106
-
-
Semenza, G.L.1
-
29
-
-
0030460724
-
Hypoxia response elements in the aldolase A, enolase 1, and lactate dehydrogenase A gene promoters contain essential binding sites for hypoxia-inducible factor 1
-
Semenza GL, Jiang BH, Leung SW, Passantino R, Concordet JP, Maire P, Giallongo A. 1996. Hypoxia response elements in the aldolase A, enolase 1, and lactate dehydrogenase A gene promoters contain essential binding sites for hypoxia-inducible factor 1. J Biol Chem 271: 32529-32537.
-
(1996)
J Biol Chem
, vol.271
, pp. 32529-32537
-
-
Semenza, G.L.1
Jiang, B.H.2
Leung, S.W.3
Passantino, R.4
Concordet, J.P.5
Maire, P.6
Giallongo, A.7
-
30
-
-
66349130218
-
Neonatal intermittent hypoxia leads to long-lasting facilitation of acute hypoxia-evoked catecholamine secretion from rat chromaffin cells
-
Souvannakitti D, Kumar GK, Fox A, Prabhakar NR. 2009. Neonatal intermittent hypoxia leads to long-lasting facilitation of acute hypoxia-evoked catecholamine secretion from rat chromaffin cells. J Neurophysiol 101: 2837-2846.
-
(2009)
J Neurophysiol
, vol.101
, pp. 2837-2846
-
-
Souvannakitti, D.1
Kumar, G.K.2
Fox, A.3
Prabhakar, N.R.4
-
31
-
-
77956202249
-
2+ channels and ryanodine receptors mediate the augmented exocytosis of catecholamines from intermittent hypoxia-treated neonatal rat chromaffin cells
-
2+ channels and ryanodine receptors mediate the augmented exocytosis of catecholamines from intermittent hypoxia-treated neonatal rat chromaffin cells. J Neurosci 30: 10763-10772.
-
(2010)
J Neurosci
, vol.30
, pp. 10763-10772
-
-
Souvannakitti, D.1
Nanduri, J.2
Yuan, G.3
Kumar, G.K.4
Fox, A.P.5
Prabhakar, N.R.6
-
32
-
-
36148987611
-
Reactive oxygen species contribute to sleep apnea-induced hypertension in rats
-
Troncoso Brindeiro CM, da Silva AQ, Allahdadi KJ, Youngblood V, Kanagy NL. 2007. Reactive oxygen species contribute to sleep apnea-induced hypertension in rats. Am J Physiol Heart Circ Physiol 293: H2971-H2976.
-
(2007)
Am J Physiol Heart Circ Physiol
, vol.293
-
-
Troncoso Brindeiro, C.M.1
da Silva, A.Q.2
Allahdadi, K.J.3
Youngblood, V.4
Kanagy, N.L.5
-
34
-
-
0037414180
-
YC-1: A potential anticancer drug targeting hypoxia-inducible factor 1
-
Yeo EJ, Chun YS, Cho YS, Kim J, Lee JC, Kim MS, Park JW. 2003. YC-1: A potential anticancer drug targeting hypoxia-inducible factor 1. J Natl Cancer Inst 95: 516-525.
-
(2003)
J Natl Cancer Inst
, vol.95
, pp. 516-525
-
-
Yeo, E.J.1
Chun, Y.S.2
Cho, Y.S.3
Kim, J.4
Lee, J.C.5
Kim, M.S.6
Park, J.W.7
-
35
-
-
14244256421
-
2+/calmodulin kinase-dependent activation of hypoxia inducible factor 1 transcriptional activity in cells subjected to intermittent hypoxia
-
2+/calmodulin kinase-dependent activation of hypoxia inducible factor 1 transcriptional activity in cells subjected to intermittent hypoxia. J Biol Chem 280: 4321-4328.
-
(2005)
J Biol Chem
, vol.280
, pp. 4321-4328
-
-
Yuan, G.1
Nanduri, J.2
Bhasker, C.R.3
Semenza, G.L.4
Prabhakar, N.R.5
-
36
-
-
54049088213
-
2+ signaling, prolyl hydroxylases, and mTOR
-
2+ signaling, prolyl hydroxylases, and mTOR. J Cell Physiol 217: 674-685.
-
(2008)
J Cell Physiol
, vol.217
, pp. 674-685
-
-
Yuan, G.1
Nanduri, J.2
Khan, S.3
Semenza, G.L.4
Prabhakar, N.R.5
-
37
-
-
25444437443
-
NADPH oxidase mediates hypersomnolence and brain oxidative injury in a murine model of sleep apnea
-
Zhan G, Serrano F, Fenik P, Hsu R, Kong L, Pratico D, Klann E, Veasey SC. 2005. NADPH oxidase mediates hypersomnolence and brain oxidative injury in a murine model of sleep apnea. Am J Respir Crit Care Med 172: 921-929.
-
(2005)
Am J Respir Crit Care Med
, vol.172
, pp. 921-929
-
-
Zhan, G.1
Serrano, F.2
Fenik, P.3
Hsu, R.4
Kong, L.5
Pratico, D.6
Klann, E.7
Veasey, S.C.8
-
38
-
-
43649104579
-
Mitochondrial autophagy is an HIF-1-dependent adaptive metabolic response to hypoxia
-
Zhang H, Bosch-Marce M, Shimoda LA, Tan YS, Baek JH, Wesley JB, Gonzalez FJ, Semenza GL. 2008a. Mitochondrial autophagy is an HIF-1-dependent adaptive metabolic response to hypoxia. J Biol Chem 283: 10892-10903.
-
(2008)
J Biol Chem
, vol.283
, pp. 10892-10903
-
-
Zhang, H.1
Bosch-Marce, M.2
Shimoda, L.A.3
Tan, Y.S.4
Baek, J.H.5
Wesley, J.B.6
Gonzalez, F.J.7
Semenza, G.L.8
-
39
-
-
58149374576
-
Digoxin and other cardiac glycosides inhibit HIF-1a synthesis and block tumor growth
-
Zhang H, Qian DZ, Tan YS, Lee K, Gao P, Ren YR, Rey S, Hammers H, Chang D, Pili R, Dang CV, Liu JO, Semenza GL. 2008b. Digoxin and other cardiac glycosides inhibit HIF-1a synthesis and block tumor growth. Proc Natl Acad Sci USA 105: 19579-19586.
-
(2008)
Proc Natl Acad Sci USA
, vol.105
, pp. 19579-19586
-
-
Zhang, H.1
Qian, D.Z.2
Tan, Y.S.3
Lee, K.4
Gao, P.5
Ren, Y.R.6
Rey, S.7
Hammers, H.8
Chang, D.9
Pili, R.10
Dang, C.V.11
Liu, J.O.12
Semenza, G.L.13
|