-
1
-
-
79955631150
-
Autophagy in the cellular energetic balance
-
R. Singh, and A.M. Cuervo Autophagy in the cellular energetic balance Cell Metab 13 2011 495 504
-
(2011)
Cell Metab
, vol.13
, pp. 495-504
-
-
Singh, R.1
Cuervo, A.M.2
-
2
-
-
27644493346
-
The pleiotropic role of autophagy: From protein metabolism to bactericide
-
N. Mizushima The pleiotropic role of autophagy: from protein metabolism to bactericide Cell Death Differ 12 2005 1535 1541
-
(2005)
Cell Death Differ
, vol.12
, pp. 1535-1541
-
-
Mizushima, N.1
-
3
-
-
79959952405
-
Liver autophagy contributes to the maintenance of blood glucose and amino acid levels
-
J. Ezaki, N. Matsumoto, M. Takeda-Ezaki, and et al. Liver autophagy contributes to the maintenance of blood glucose and amino acid levels Autophagy 7 2011 727 736
-
(2011)
Autophagy
, vol.7
, pp. 727-736
-
-
Ezaki, J.1
Matsumoto, N.2
Takeda-Ezaki, M.3
-
4
-
-
11144245626
-
The role of autophagy during the early neonatal starvation period
-
A. Kuma, M. Hatano, M. Matsui, and et al. The role of autophagy during the early neonatal starvation period Nature 432 2004 1032 1036
-
(2004)
Nature
, vol.432
, pp. 1032-1036
-
-
Kuma, A.1
Hatano, M.2
Matsui, M.3
-
5
-
-
57049094929
-
Suppression of autophagy in skeletal muscle uncovers the accumulation of ubiquitinated proteins and their potential role in muscle damage in Pompe disease
-
N. Raben, V. Hill, L. Shea, and et al. Suppression of autophagy in skeletal muscle uncovers the accumulation of ubiquitinated proteins and their potential role in muscle damage in Pompe disease Hum Mol Genet 17 2008 3897 3908
-
(2008)
Hum Mol Genet
, vol.17
, pp. 3897-3908
-
-
Raben, N.1
Hill, V.2
Shea, L.3
-
6
-
-
65949095803
-
Autophagy regulates lipid metabolism
-
R. Singh, S. Kaushik, Y. Wang, and et al. Autophagy regulates lipid metabolism Nature 458 2009 1131 1135
-
(2009)
Nature
, vol.458
, pp. 1131-1135
-
-
Singh, R.1
Kaushik, S.2
Wang, Y.3
-
7
-
-
39849109338
-
Autophagy fights disease through cellular self-digestion
-
N. Mizushima, B. Levine, A.M. Cuervo, and et al. Autophagy fights disease through cellular self-digestion Nature 451 2008 1069 1075
-
(2008)
Nature
, vol.451
, pp. 1069-1075
-
-
Mizushima, N.1
Levine, B.2
Cuervo, A.M.3
-
8
-
-
0014148066
-
Participation of lysosomes in cellular autophagy induced in rat liver by glucagon
-
R.L. Deter, P. Baudhuin, and C. De Duve Participation of lysosomes in cellular autophagy induced in rat liver by glucagon J Cell Biol 35 1967 C11 C16
-
(1967)
J Cell Biol
, vol.35
, pp. C11-C16
-
-
Deter, R.L.1
Baudhuin, P.2
De Duve, C.3
-
9
-
-
84937639381
-
Eaten alive: Novel insights into autophagy from multicellular model systems
-
H. Zhang, and E.H. Baehrecke Eaten alive: novel insights into autophagy from multicellular model systems Trends Cell Biol 25 2015 376 387
-
(2015)
Trends Cell Biol
, vol.25
, pp. 376-387
-
-
Zhang, H.1
Baehrecke, E.H.2
-
10
-
-
51449085299
-
The role of autophagy in mammalian development: Cell makeover rather than cell death
-
F. Cecconi, and B. Levine The role of autophagy in mammalian development: cell makeover rather than cell death Dev Cell 15 2008 344 357
-
(2008)
Dev Cell
, vol.15
, pp. 344-357
-
-
Cecconi, F.1
Levine, B.2
-
11
-
-
84904690794
-
Variants of mitochondrial autophagy: Types 1 and 2 mitophagy and micromitophagy (type 3)
-
J.J. Lemasters Variants of mitochondrial autophagy: types 1 and 2 mitophagy and micromitophagy (type 3) Redox Biol 2 2014 749 754
-
(2014)
Redox Biol
, vol.2
, pp. 749-754
-
-
Lemasters, J.J.1
-
12
-
-
84887387419
-
After the banquet: Mitochondrial biogenesis, mitophagy, and cell survival
-
J. Zhu, K.Z. Wang, and C.T. Chu After the banquet: mitochondrial biogenesis, mitophagy, and cell survival Autophagy 9 2013 1663 1676
-
(2013)
Autophagy
, vol.9
, pp. 1663-1676
-
-
Zhu, J.1
Wang, K.Z.2
Chu, C.T.3
-
13
-
-
84913592131
-
Deficient chaperone-mediated autophagy in liver leads to metabolic dysregulation
-
J.L. Schneider, Y. Suh, and A.M. Cuervo Deficient chaperone-mediated autophagy in liver leads to metabolic dysregulation Cell Metab 20 2014 417 432
-
(2014)
Cell Metab
, vol.20
, pp. 417-432
-
-
Schneider, J.L.1
Suh, Y.2
Cuervo, A.M.3
-
14
-
-
84922311450
-
Fatty acid synthase is preferentially degraded by autophagy upon nitrogen starvation in yeast
-
T. Shpilka, E. Welter, N. Borovsky, and et al. Fatty acid synthase is preferentially degraded by autophagy upon nitrogen starvation in yeast Proc Natl Acad Sci U S A 112 2015 1434 1439
-
(2015)
Proc Natl Acad Sci U S A
, vol.112
, pp. 1434-1439
-
-
Shpilka, T.1
Welter, E.2
Borovsky, N.3
-
15
-
-
84891747382
-
The machinery of macroautophagy
-
Y. Feng, D. He, Z. Yao, and et al. The machinery of macroautophagy Cell Res 24 2014 24 41
-
(2014)
Cell Res
, vol.24
, pp. 24-41
-
-
Feng, Y.1
He, D.2
Yao, Z.3
-
16
-
-
84892875805
-
At the end of the autophagic road: An emerging understanding of lysosomal functions in autophagy
-
H.M. Shen, and N. Mizushima At the end of the autophagic road: an emerging understanding of lysosomal functions in autophagy Trends Biochem Sci 39 2014 61 71
-
(2014)
Trends Biochem Sci
, vol.39
, pp. 61-71
-
-
Shen, H.M.1
Mizushima, N.2
-
17
-
-
84864318195
-
Chaperone-mediated autophagy: A unique way to enter the lysosome world
-
S. Kaushik, and A.M. Cuervo Chaperone-mediated autophagy: a unique way to enter the lysosome world Trends Cell Biol 22 2012 407 417
-
(2012)
Trends Cell Biol
, vol.22
, pp. 407-417
-
-
Kaushik, S.1
Cuervo, A.M.2
-
18
-
-
84901815187
-
Cargo recognition and trafficking in selective autophagy
-
A. Stolz, A. Ernst, and I. Dikic Cargo recognition and trafficking in selective autophagy Nat Cell Biol 16 2014 495 501
-
(2014)
Nat Cell Biol
, vol.16
, pp. 495-501
-
-
Stolz, A.1
Ernst, A.2
Dikic, I.3
-
20
-
-
84885661260
-
Functional interaction between autophagy and ciliogenesis
-
O. Pampliega, I. Orhon, B. Patel, and et al. Functional interaction between autophagy and ciliogenesis Nature 502 2013 194 200
-
(2013)
Nature
, vol.502
, pp. 194-200
-
-
Pampliega, O.1
Orhon, I.2
Patel, B.3
-
21
-
-
84899977406
-
Connexins modulate autophagosome biogenesis
-
E. Bejarano, A. Yuste, B. Patel, and et al. Connexins modulate autophagosome biogenesis Nat Cell Biol 16 2014 401 414
-
(2014)
Nat Cell Biol
, vol.16
, pp. 401-414
-
-
Bejarano, E.1
Yuste, A.2
Patel, B.3
-
22
-
-
80955177196
-
TFEB links autophagy to lysosomal biogenesis
-
C. Settembre, C. Di Malta, V.A. Polito, and et al. TFEB links autophagy to lysosomal biogenesis Science 332 2011 1429 1433
-
(2011)
Science
, vol.332
, pp. 1429-1433
-
-
Settembre, C.1
Di Malta, C.2
Polito, V.A.3
-
23
-
-
84878606239
-
TFEB controls cellular lipid metabolism through a starvation-induced autoregulatory loop
-
C. Settembre, R. De Cegli, G. Mansueto, and et al. TFEB controls cellular lipid metabolism through a starvation-induced autoregulatory loop Nat Cell Biol 15 2013 647 658
-
(2013)
Nat Cell Biol
, vol.15
, pp. 647-658
-
-
Settembre, C.1
De Cegli, R.2
Mansueto, G.3
-
24
-
-
84878533962
-
MXL-3 and HLH-30 transcriptionally link lipolysis and autophagy to nutrient availability
-
E.J. O'Rourke, and G. Ruvkun MXL-3 and HLH-30 transcriptionally link lipolysis and autophagy to nutrient availability Nat Cell Biol 15 2013 668 676
-
(2013)
Nat Cell Biol
, vol.15
, pp. 668-676
-
-
O'Rourke, E.J.1
Ruvkun, G.2
-
25
-
-
84893055506
-
The nutrient-responsive transcription factor TFE3 promotes autophagy, lysosomal biogenesis, and clearance of cellular debris
-
J.A. Martina, H.I. Diab, L. Lishu, and et al. The nutrient-responsive transcription factor TFE3 promotes autophagy, lysosomal biogenesis, and clearance of cellular debris Sci Signal 7 2014 ra9
-
(2014)
Sci Signal
, vol.7
, pp. ra9
-
-
Martina, J.A.1
Diab, H.I.2
Lishu, L.3
-
26
-
-
84922968506
-
Transcriptional regulation of autophagy by an FXR-CREB axis
-
S. Seok, T. Fu, S.E. Choi, and et al. Transcriptional regulation of autophagy by an FXR-CREB axis Nature 516 2014 108 111
-
(2014)
Nature
, vol.516
, pp. 108-111
-
-
Seok, S.1
Fu, T.2
Choi, S.E.3
-
27
-
-
84923031534
-
Nutrient-sensing nuclear receptors coordinate autophagy
-
J.M. Lee, M. Wagner, R. Xiao, and et al. Nutrient-sensing nuclear receptors coordinate autophagy Nature 516 2014 112 115
-
(2014)
Nature
, vol.516
, pp. 112-115
-
-
Lee, J.M.1
Wagner, M.2
Xiao, R.3
-
28
-
-
0025294506
-
Peptide sequences that target cytosolic proteins for lysosomal proteolysis
-
J.F. Dice Peptide sequences that target cytosolic proteins for lysosomal proteolysis Trends Biochem Sci 15 1990 305 309
-
(1990)
Trends Biochem Sci
, vol.15
, pp. 305-309
-
-
Dice, J.F.1
-
29
-
-
51349130544
-
The chaperone-mediated autophagy receptor organizes in dynamic protein complexes at the lysosomal membrane
-
U. Bandyopadhyay, S. Kaushik, L. Varticovski, and et al. The chaperone-mediated autophagy receptor organizes in dynamic protein complexes at the lysosomal membrane Mol Cell Biol 28 2008 5747 5763
-
(2008)
Mol Cell Biol
, vol.28
, pp. 5747-5763
-
-
Bandyopadhyay, U.1
Kaushik, S.2
Varticovski, L.3
-
30
-
-
0034232418
-
Regulation of lamp2a levels in the lysosomal membrane
-
A.M. Cuervo, and J.F. Dice Regulation of lamp2a levels in the lysosomal membrane Traffic 1 2000 570 583
-
(2000)
Traffic
, vol.1
, pp. 570-583
-
-
Cuervo, A.M.1
Dice, J.F.2
-
31
-
-
0028848119
-
Activation of a selective pathway of lysosomal proteolysis in rat liver by prolonged starvation
-
A.M. Cuervo, E. Knecht, S.R. Terlecky, and et al. Activation of a selective pathway of lysosomal proteolysis in rat liver by prolonged starvation Am J Physiol 269 1995 C1200 C1208
-
(1995)
Am J Physiol
, vol.269
, pp. C1200-C1208
-
-
Cuervo, A.M.1
Knecht, E.2
Terlecky, S.R.3
-
32
-
-
84895930872
-
Liver autophagy: Much more than just taking out the trash
-
J.L. Schneider, and A.M. Cuervo Liver autophagy: much more than just taking out the trash Nat Rev Gastroenterol Hepatol 11 2014 187 200
-
(2014)
Nat Rev Gastroenterol Hepatol
, vol.11
, pp. 187-200
-
-
Schneider, J.L.1
Cuervo, A.M.2
-
33
-
-
84879121285
-
Chemical modulation of chaperone-mediated autophagy by retinoic acid derivatives
-
J. Anguiano, T.P. Garner, M. Mahalingam, and et al. Chemical modulation of chaperone-mediated autophagy by retinoic acid derivatives Nat Chem Biol 9 2013 374 382
-
(2013)
Nat Chem Biol
, vol.9
, pp. 374-382
-
-
Anguiano, J.1
Garner, T.P.2
Mahalingam, M.3
-
34
-
-
84908207126
-
Chaperone-mediated autophagy regulates T cell responses through targeted degradation of negative regulators of T cell activation
-
R. Valdor, E. Mocholi, Y. Botbol, and et al. Chaperone-mediated autophagy regulates T cell responses through targeted degradation of negative regulators of T cell activation Nat Immunol 15 2014 1046 1054
-
(2014)
Nat Immunol
, vol.15
, pp. 1046-1054
-
-
Valdor, R.1
Mocholi, E.2
Botbol, Y.3
-
35
-
-
21844440290
-
Ketone bodies stimulate chaperone-mediated autophagy
-
P.F. Finn, and J.F. Dice Ketone bodies stimulate chaperone-mediated autophagy J Biol Chem 280 2005 25864 25870
-
(2005)
J Biol Chem
, vol.280
, pp. 25864-25870
-
-
Finn, P.F.1
Dice, J.F.2
-
36
-
-
84858659826
-
Inhibitory effect of dietary lipids on chaperone-mediated autophagy
-
J.A. Rodriguez-Navarro, S. Kaushik, H. Koga, and et al. Inhibitory effect of dietary lipids on chaperone-mediated autophagy Proc Natl Acad Sci U S A 109 2012 E705 E714
-
(2012)
Proc Natl Acad Sci U S A
, vol.109
, pp. E705-E714
-
-
Rodriguez-Navarro, J.A.1
Kaushik, S.2
Koga, H.3
-
37
-
-
51349095898
-
Restoration of chaperone-mediated autophagy in aging liver improves cellular maintenance and hepatic function
-
C. Zhang, and A.M. Cuervo Restoration of chaperone-mediated autophagy in aging liver improves cellular maintenance and hepatic function Nat Med 14 2008 959 965
-
(2008)
Nat Med
, vol.14
, pp. 959-965
-
-
Zhang, C.1
Cuervo, A.M.2
-
38
-
-
0020510501
-
Quantitative correlation between proteolysis and macro- and microautophagy in mouse hepatocytes during starvation and refeeding
-
G.E. Mortimore, N.J. Hutson, and C.A. Surmacz Quantitative correlation between proteolysis and macro- and microautophagy in mouse hepatocytes during starvation and refeeding Proc Natl Acad Sci U S A 80 1983 2179 2183
-
(1983)
Proc Natl Acad Sci U S A
, vol.80
, pp. 2179-2183
-
-
Mortimore, G.E.1
Hutson, N.J.2
Surmacz, C.A.3
-
39
-
-
84871002139
-
Selective autophagy in budding yeast
-
K. Suzuki Selective autophagy in budding yeast Cell Death Differ 20 2013 43 48
-
(2013)
Cell Death Differ
, vol.20
, pp. 43-48
-
-
Suzuki, K.1
-
40
-
-
84934440405
-
Microautophagy in the yeast Saccharomyces cerevisiae
-
A. Uttenweiler, and A. Mayer Microautophagy in the yeast Saccharomyces cerevisiae Methods Mol Biol 445 2008 245 259
-
(2008)
Methods Mol Biol
, vol.445
, pp. 245-259
-
-
Uttenweiler, A.1
Mayer, A.2
-
41
-
-
84892536117
-
Lipid droplet autophagy in the yeast Saccharomyces cerevisiae
-
T. van Zutphen, V. Todde, R. de Boer, and et al. Lipid droplet autophagy in the yeast Saccharomyces cerevisiae Mol Biol Cell 25 2014 290 301
-
(2014)
Mol Biol Cell
, vol.25
, pp. 290-301
-
-
Van Zutphen, T.1
Todde, V.2
De Boer, R.3
-
42
-
-
78651423598
-
Microautophagy of cytosolic proteins by late endosomes
-
R. Sahu, S. Kaushik, C.C. Clement, and et al. Microautophagy of cytosolic proteins by late endosomes Dev Cell 20 2011 131 139
-
(2011)
Dev Cell
, vol.20
, pp. 131-139
-
-
Sahu, R.1
Kaushik, S.2
Clement, C.C.3
-
43
-
-
1542289063
-
Amino acids and insulin control autophagic proteolysis through different signaling pathways in relation to mTOR in isolated rat hepatocytes
-
T. Kanazawa, I. Taneike, R. Akaishi, and et al. Amino acids and insulin control autophagic proteolysis through different signaling pathways in relation to mTOR in isolated rat hepatocytes J Biol Chem 279 2004 8452 8459
-
(2004)
J Biol Chem
, vol.279
, pp. 8452-8459
-
-
Kanazawa, T.1
Taneike, I.2
Akaishi, R.3
-
44
-
-
80053476420
-
The autophagy initiating kinase ULK1 is regulated via opposing phosphorylation by AMPK and mTOR
-
D. Egan, J. Kim, R.J. Shaw, and et al. The autophagy initiating kinase ULK1 is regulated via opposing phosphorylation by AMPK and mTOR Autophagy 7 2011 643 644
-
(2011)
Autophagy
, vol.7
, pp. 643-644
-
-
Egan, D.1
Kim, J.2
Shaw, R.J.3
-
45
-
-
84862777407
-
Leucyl-tRNA synthetase is an intracellular leucine sensor for the mTORC1-signaling pathway
-
J.M. Han, S.J. Jeong, M.C. Park, and et al. Leucyl-tRNA synthetase is an intracellular leucine sensor for the mTORC1-signaling pathway Cell 149 2012 410 424
-
(2012)
Cell
, vol.149
, pp. 410-424
-
-
Han, J.M.1
Jeong, S.J.2
Park, M.C.3
-
46
-
-
84857997408
-
A lysosome-to-nucleus signalling mechanism senses and regulates the lysosome via mTOR and TFEB
-
C. Settembre, R. Zoncu, D.L. Medina, and et al. A lysosome-to-nucleus signalling mechanism senses and regulates the lysosome via mTOR and TFEB EMBO J 31 2012 1095 1108
-
(2012)
EMBO J
, vol.31
, pp. 1095-1108
-
-
Settembre, C.1
Zoncu, R.2
Medina, D.L.3
-
47
-
-
59049087460
-
Bidirectional transport of amino acids regulates mTOR and autophagy
-
P. Nicklin, P. Bergman, B. Zhang, and et al. Bidirectional transport of amino acids regulates mTOR and autophagy Cell 136 2009 521 534
-
(2009)
Cell
, vol.136
, pp. 521-534
-
-
Nicklin, P.1
Bergman, P.2
Zhang, B.3
-
48
-
-
73649187940
-
Alpha-Glucosidase deficiency in generalized glycogenstorage disease (Pompe's disease)
-
H.G. Hers alpha-Glucosidase deficiency in generalized glycogenstorage disease (Pompe's disease) Biochem J 86 1963 11 16
-
(1963)
Biochem J
, vol.86
, pp. 11-16
-
-
Hers, H.G.1
-
49
-
-
78049409236
-
Starch binding domain-containing protein 1/genethonin 1 is a novel participant in glycogen metabolism
-
S. Jiang, B. Heller, V.S. Tagliabracci, and et al. Starch binding domain-containing protein 1/genethonin 1 is a novel participant in glycogen metabolism J Biol Chem 285 2010 34960 34971
-
(2010)
J Biol Chem
, vol.285
, pp. 34960-34971
-
-
Jiang, S.1
Heller, B.2
Tagliabracci, V.S.3
-
50
-
-
21644475161
-
Glycogen autophagy in the liver and heart of newborn rats. the effects of glucagon, adrenalin or rapamycin
-
D.J. Kondomerkos, S.A. Kalamidas, O.B. Kotoulas, and et al. Glycogen autophagy in the liver and heart of newborn rats. The effects of glucagon, adrenalin or rapamycin Histol Histopathol 20 2005 689 696
-
(2005)
Histol Histopathol
, vol.20
, pp. 689-696
-
-
Kondomerkos, D.J.1
Kalamidas, S.A.2
Kotoulas, O.B.3
-
51
-
-
84921822489
-
Reduced autophagy in livers of fasted, fat-depleted, ghrelin-deficient mice: Reversal by growth hormone
-
Y. Zhang, F. Fang, J.L. Goldstein, and et al. Reduced autophagy in livers of fasted, fat-depleted, ghrelin-deficient mice: reversal by growth hormone Proc Natl Acad Sci U S A 112 2015 1226 1231
-
(2015)
Proc Natl Acad Sci U S A
, vol.112
, pp. 1226-1231
-
-
Zhang, Y.1
Fang, F.2
Goldstein, J.L.3
-
52
-
-
84929606449
-
The small GTPase Rab7 as a central regulator of hepatocellular lipophagy
-
B. Schroeder, R.J. Schulze, S.G. Weller, and et al. The small GTPase Rab7 as a central regulator of hepatocellular lipophagy Hepatology 61 2015 1896 1907
-
(2015)
Hepatology
, vol.61
, pp. 1896-1907
-
-
Schroeder, B.1
Schulze, R.J.2
Weller, S.G.3
-
53
-
-
84930182353
-
Degradation of lipid droplet-associated proteins by chaperone-mediated autophagy facilitates lipolysis
-
S. Kaushik, and A.M. Cuervo Degradation of lipid droplet-associated proteins by chaperone-mediated autophagy facilitates lipolysis Nat Cell Biol 17 2015 759 770
-
(2015)
Nat Cell Biol
, vol.17
, pp. 759-770
-
-
Kaushik, S.1
Cuervo, A.M.2
-
54
-
-
27144506185
-
The CREB coactivator TORC2 is a key regulator of fasting glucose metabolism
-
S.H. Koo, L. Flechner, L. Qi, and et al. The CREB coactivator TORC2 is a key regulator of fasting glucose metabolism Nature 437 2005 1109 1111
-
(2005)
Nature
, vol.437
, pp. 1109-1111
-
-
Koo, S.H.1
Flechner, L.2
Qi, L.3
-
55
-
-
84893396046
-
Suppression of autophagic flux by bile acids in hepatocytes
-
S. Manley, H.M. Ni, B. Kong, and et al. Suppression of autophagic flux by bile acids in hepatocytes Toxicol Sci 137 2014 478 490
-
(2014)
Toxicol Sci
, vol.137
, pp. 478-490
-
-
Manley, S.1
Ni, H.M.2
Kong, B.3
-
56
-
-
77955789211
-
Altered lipid content inhibits autophagic vesicular fusion
-
H. Koga, S. Kaushik, and A.M. Cuervo Altered lipid content inhibits autophagic vesicular fusion FASEB J 24 2010 3052 3065
-
(2010)
FASEB J
, vol.24
, pp. 3052-3065
-
-
Koga, H.1
Kaushik, S.2
Cuervo, A.M.3
-
57
-
-
79955623510
-
During autophagy mitochondria elongate, are spared from degradation and sustain cell viability
-
L.C. Gomes, G. Di Benedetto, and L. Scorrano During autophagy mitochondria elongate, are spared from degradation and sustain cell viability Nat Cell Biol 13 2011 589 598
-
(2011)
Nat Cell Biol
, vol.13
, pp. 589-598
-
-
Gomes, L.C.1
Di Benedetto, G.2
Scorrano, L.3
-
58
-
-
84926624248
-
Hypoxia activation of mitophagy and its role in disease pathogenesis
-
H. Wu, and Q. Chen Hypoxia activation of mitophagy and its role in disease pathogenesis Antioxid Redox Signal 22 2015 1032 1046
-
(2015)
Antioxid Redox Signal
, vol.22
, pp. 1032-1046
-
-
Wu, H.1
Chen, Q.2
-
59
-
-
84921369563
-
The roles of PINK1, parkin, and mitochondrial fidelity in Parkinson's disease
-
A.M. Pickrell, and R.J. Youle The roles of PINK1, parkin, and mitochondrial fidelity in Parkinson's disease Neuron 85 2015 257 273
-
(2015)
Neuron
, vol.85
, pp. 257-273
-
-
Pickrell, A.M.1
Youle, R.J.2
-
60
-
-
79251587803
-
Phosphorylation of ULK1 (hATG1) by AMP-activated protein kinase connects energy sensing to mitophagy
-
D.F. Egan, D.B. Shackelford, M.M. Mihaylova, and et al. Phosphorylation of ULK1 (hATG1) by AMP-activated protein kinase connects energy sensing to mitophagy Science 331 2011 456 461
-
(2011)
Science
, vol.331
, pp. 456-461
-
-
Egan, D.F.1
Shackelford, D.B.2
Mihaylova, M.M.3
-
61
-
-
84923147814
-
Regulation of TFEB-PGC1alpha axis by BECLIN-1 controls mitochondrial quality and cardiomyocyte death under stress
-
X. Ma, H. Liu, J.T. Murphy, and et al. Regulation of TFEB-PGC1alpha axis by BECLIN-1 controls mitochondrial quality and cardiomyocyte death under stress Mol Cell Biol 35 2015 956 976
-
(2015)
Mol Cell Biol
, vol.35
, pp. 956-976
-
-
Ma, X.1
Liu, H.2
Murphy, J.T.3
-
62
-
-
79959371914
-
Acetylation targets the M2 isoform of pyruvate kinase for degradation through chaperone-mediated autophagy and promotes tumor growth
-
L. Lv, D. Li, D. Zhao, and et al. Acetylation targets the M2 isoform of pyruvate kinase for degradation through chaperone-mediated autophagy and promotes tumor growth Mol Cell 42 2011 719 730
-
(2011)
Mol Cell
, vol.42
, pp. 719-730
-
-
Lv, L.1
Li, D.2
Zhao, D.3
-
63
-
-
40749163248
-
The M2 splice isoform of pyruvate kinase is important for cancer metabolism and tumour growth
-
H.R. Christofk, M.G. Vander Heiden, M.H. Harris, and et al. The M2 splice isoform of pyruvate kinase is important for cancer metabolism and tumour growth Nature 452 2008 230 233
-
(2008)
Nature
, vol.452
, pp. 230-233
-
-
Christofk, H.R.1
Vander Heiden, M.G.2
Harris, M.H.3
-
64
-
-
81455128769
-
Chaperone-mediated autophagy is required for tumor growth
-
M. Kon, R. Kiffin, H. Koga, and et al. Chaperone-mediated autophagy is required for tumor growth Sci Transl Med 3 2011 109ra117
-
(2011)
Sci Transl Med
, vol.3
, pp. 109ra117
-
-
Kon, M.1
Kiffin, R.2
Koga, H.3
-
65
-
-
84928023582
-
Regulated degradation of Chk1 by chaperone-mediated autophagy in response to DNA damage
-
C. Park, Y. Suh, and A.M. Cuervo Regulated degradation of Chk1 by chaperone-mediated autophagy in response to DNA damage Nat Commun 6 2015 6823
-
(2015)
Nat Commun
, vol.6
, pp. 6823
-
-
Park, C.1
Suh, Y.2
Cuervo, A.M.3
-
67
-
-
21044455137
-
Impairment of starvation-induced and constitutive autophagy in Atg7-deficient mice
-
M. Komatsu, S. Waguri, T. Ueno, and et al. Impairment of starvation-induced and constitutive autophagy in Atg7-deficient mice J Cell Biol 169 2005 425 434
-
(2005)
J Cell Biol
, vol.169
, pp. 425-434
-
-
Komatsu, M.1
Waguri, S.2
Ueno, T.3
-
68
-
-
77956400005
-
Defective hepatic autophagy in obesity promotes ER stress and causes insulin resistance
-
L. Yang, P. Li, S. Fu, and et al. Defective hepatic autophagy in obesity promotes ER stress and causes insulin resistance Cell Metab 11 2010 467 478
-
(2010)
Cell Metab
, vol.11
, pp. 467-478
-
-
Yang, L.1
Li, P.2
Fu, S.3
-
69
-
-
78651393239
-
A role for mitochondria in NLRP3 inflammasome activation
-
R. Zhou, A.S. Yazdi, P. Menu, and et al. A role for mitochondria in NLRP3 inflammasome activation Nature 469 2011 221 225
-
(2011)
Nature
, vol.469
, pp. 221-225
-
-
Zhou, R.1
Yazdi, A.S.2
Menu, P.3
-
70
-
-
6344275803
-
Activation of chaperone-mediated autophagy during oxidative stress
-
R. Kiffin, C. Christian, E. Knecht, and et al. Activation of chaperone-mediated autophagy during oxidative stress Mol Biol Cell 15 2004 4829 4840
-
(2004)
Mol Biol Cell
, vol.15
, pp. 4829-4840
-
-
Kiffin, R.1
Christian, C.2
Knecht, E.3
-
71
-
-
84924235659
-
Loss of hepatic chaperone-mediated autophagy accelerates proteostasis failure in aging
-
J.L. Schneider, J. Villarroya, A. Diaz-Carretero, and et al. Loss of hepatic chaperone-mediated autophagy accelerates proteostasis failure in aging Aging Cell 14 2015 249 264
-
(2015)
Aging Cell
, vol.14
, pp. 249-264
-
-
Schneider, J.L.1
Villarroya, J.2
Diaz-Carretero, A.3
-
72
-
-
71449091240
-
Hepatic autophagy is suppressed in the presence of insulin resistance and hyperinsulinemia: Inhibition of FoxO1-dependent expression of key autophagy genes by insulin
-
H.Y. Liu, J. Han, S.Y. Cao, and et al. Hepatic autophagy is suppressed in the presence of insulin resistance and hyperinsulinemia: inhibition of FoxO1-dependent expression of key autophagy genes by insulin J Biol Chem 284 2009 31484 31492
-
(2009)
J Biol Chem
, vol.284
, pp. 31484-31492
-
-
Liu, H.Y.1
Han, J.2
Cao, S.Y.3
-
73
-
-
84901062946
-
Impaired autophagic flux is associated with increased endoplasmic reticulum stress during the development of NAFLD
-
A. Gonzalez-Rodriguez, R. Mayoral, N. Agra, and et al. Impaired autophagic flux is associated with increased endoplasmic reticulum stress during the development of NAFLD Cell Death Dis 5 2014 e1179
-
(2014)
Cell Death Dis
, vol.5
, pp. e1179
-
-
Gonzalez-Rodriguez, A.1
Mayoral, R.2
Agra, N.3
-
74
-
-
80052617116
-
Hepatic steatosis inhibits autophagic proteolysis via impairment of autophagosomal acidification and cathepsin expression
-
Y. Inami, S. Yamashina, K. Izumi, and et al. Hepatic steatosis inhibits autophagic proteolysis via impairment of autophagosomal acidification and cathepsin expression Biochem Biophys Res Commun 412 2011 618 625
-
(2011)
Biochem Biophys Res Commun
, vol.412
, pp. 618-625
-
-
Inami, Y.1
Yamashina, S.2
Izumi, K.3
-
75
-
-
84926252071
-
Autophagy in malignant transformation and cancer progression
-
L. Galluzzi, F. Pietrocola, J.M. Bravo-San Pedro, and et al. Autophagy in malignant transformation and cancer progression EMBO J 34 2015 856 880
-
(2015)
EMBO J
, vol.34
, pp. 856-880
-
-
Galluzzi, L.1
Pietrocola, F.2
Bravo-San Pedro, J.M.3
-
76
-
-
56449107131
-
Association of autophagy defect with a malignant phenotype and poor prognosis of hepatocellular carcinoma
-
Z.B. Ding, Y.H. Shi, J. Zhou, and et al. Association of autophagy defect with a malignant phenotype and poor prognosis of hepatocellular carcinoma Cancer Res 68 2008 9167 9175
-
(2008)
Cancer Res
, vol.68
, pp. 9167-9175
-
-
Ding, Z.B.1
Shi, Y.H.2
Zhou, J.3
-
77
-
-
79955377420
-
Autophagy-deficient mice develop multiple liver tumors
-
A. Takamura, M. Komatsu, T. Hara, and et al. Autophagy-deficient mice develop multiple liver tumors Genes Dev 25 2011 795 800
-
(2011)
Genes Dev
, vol.25
, pp. 795-800
-
-
Takamura, A.1
Komatsu, M.2
Hara, T.3
-
78
-
-
84906315540
-
Nrf2 promotes the development of fibrosis and tumorigenesis in mice with defective hepatic autophagy
-
H.M. Ni, B.L. Woolbright, J. Williams, and et al. Nrf2 promotes the development of fibrosis and tumorigenesis in mice with defective hepatic autophagy J Hepatol 61 2014 617 625
-
(2014)
J Hepatol
, vol.61
, pp. 617-625
-
-
Ni, H.M.1
Woolbright, B.L.2
Williams, J.3
-
79
-
-
79955492012
-
Persistent activation of Nrf2 through p62 in hepatocellular carcinoma cells
-
Y. Inami, S. Waguri, A. Sakamoto, and et al. Persistent activation of Nrf2 through p62 in hepatocellular carcinoma cells J Cell Biol 193 2011 275 284
-
(2011)
J Cell Biol
, vol.193
, pp. 275-284
-
-
Inami, Y.1
Waguri, S.2
Sakamoto, A.3
-
80
-
-
51649130168
-
Cancer related mutations in NRF2 impair its recognition by Keap1-Cul3 E3 ligase and promote malignancy
-
T. Shibata, T. Ohta, K.I. Tong, and et al. Cancer related mutations in NRF2 impair its recognition by Keap1-Cul3 E3 ligase and promote malignancy Proc Natl Acad Sci U S A 105 2008 13568 13573
-
(2008)
Proc Natl Acad Sci U S A
, vol.105
, pp. 13568-13573
-
-
Shibata, T.1
Ohta, T.2
Tong, K.I.3
-
81
-
-
84863022322
-
Genes associated with recurrence of hepatocellular carcinoma: Integrated analysis by gene expression and methylation profiling
-
J.D. Yang, S.Y. Seol, S.H. Leem, and et al. Genes associated with recurrence of hepatocellular carcinoma: integrated analysis by gene expression and methylation profiling J Korean Med Sci 26 2011 1428 1438
-
(2011)
J Korean Med Sci
, vol.26
, pp. 1428-1438
-
-
Yang, J.D.1
Seol, S.Y.2
Leem, S.H.3
-
82
-
-
84888800151
-
Resveratrol modulates autophagy and NF-kappaB activity in a murine model for treating non-alcoholic fatty liver disease
-
L. Li, J. Hai, Z. Li, and et al. Resveratrol modulates autophagy and NF-kappaB activity in a murine model for treating non-alcoholic fatty liver disease Food Chem Toxicol 63 2014 166 173
-
(2014)
Food Chem Toxicol
, vol.63
, pp. 166-173
-
-
Li, L.1
Hai, J.2
Li, Z.3
-
83
-
-
84859444880
-
Autophagy releases lipid that promotes fibrogenesis by activated hepatic stellate cells in mice and in human tissues
-
V. Hernandez-Gea, Z. Ghiassi-Nejad, R. Rozenfeld, and et al. Autophagy releases lipid that promotes fibrogenesis by activated hepatic stellate cells in mice and in human tissues Gastroenterology 142 2012 938 946
-
(2012)
Gastroenterology
, vol.142
, pp. 938-946
-
-
Hernandez-Gea, V.1
Ghiassi-Nejad, Z.2
Rozenfeld, R.3
-
84
-
-
84922133228
-
Pharmacological correction of obesity-induced autophagy arrest using calcium channel blockers
-
H.W. Park, H. Park, I.A. Semple, and et al. Pharmacological correction of obesity-induced autophagy arrest using calcium channel blockers Nat Commun 5 2014 4834
-
(2014)
Nat Commun
, vol.5
, pp. 4834
-
-
Park, H.W.1
Park, H.2
Semple, I.A.3
-
85
-
-
84876287362
-
Pharmacological promotion of autophagy alleviates steatosis and injury in alcoholic and non-alcoholic fatty liver conditions in mice
-
C.W. Lin, H. Zhang, M. Li, and et al. Pharmacological promotion of autophagy alleviates steatosis and injury in alcoholic and non-alcoholic fatty liver conditions in mice J Hepatol 58 2013 993 999
-
(2013)
J Hepatol
, vol.58
, pp. 993-999
-
-
Lin, C.W.1
Zhang, H.2
Li, M.3
-
86
-
-
84919712770
-
Caloric restriction mimetics: Natural/physiological pharmacological autophagy inducers
-
G. Marino, F. Pietrocola, F. Madeo, and et al. Caloric restriction mimetics: natural/physiological pharmacological autophagy inducers Autophagy 10 2014 1879 1882
-
(2014)
Autophagy
, vol.10
, pp. 1879-1882
-
-
Marino, G.1
Pietrocola, F.2
Madeo, F.3
-
87
-
-
67650439330
-
Caloric restriction delays disease onset and mortality in rhesus monkeys
-
R.J. Colman, R.M. Anderson, S.C. Johnson, and et al. Caloric restriction delays disease onset and mortality in rhesus monkeys Science 325 2009 201 204
-
(2009)
Science
, vol.325
, pp. 201-204
-
-
Colman, R.J.1
Anderson, R.M.2
Johnson, S.C.3
-
88
-
-
84866163081
-
Impact of caloric restriction on health and survival in rhesus monkeys from the NIA study
-
J.A. Mattison, G.S. Roth, T.M. Beasley, and et al. Impact of caloric restriction on health and survival in rhesus monkeys from the NIA study Nature 489 2012 318 321
-
(2012)
Nature
, vol.489
, pp. 318-321
-
-
Mattison, J.A.1
Roth, G.S.2
Beasley, T.M.3
-
89
-
-
84863393597
-
Exercise-induced BCL2-regulated autophagy is required for muscle glucose homeostasis
-
C. He, M.C. Bassik, V. Moresi, and et al. Exercise-induced BCL2-regulated autophagy is required for muscle glucose homeostasis Nature 481 2012 511 515
-
(2012)
Nature
, vol.481
, pp. 511-515
-
-
He, C.1
Bassik, M.C.2
Moresi, V.3
|