-
2
-
-
0036274359
-
The fundamental role of epigenetic events in cancer
-
Jones PA, Baylin SB. The fundamental role of epigenetic events in cancer. Nat Rev Genet 2002; 3: 415-28.
-
(2002)
Nat Rev Genet
, vol.3
, pp. 415-428
-
-
Jones, P.A.1
Baylin, S.B.2
-
3
-
-
46249085489
-
Factor VM Thorgeirsson SS. Transforming growth factorbeta gene expression signature in mouse hepatocytes predicts clinical outcome in human cancer
-
Coulouarn C, Factor VM, Thorgeirsson SS. Transforming growth factorbeta gene expression signature in mouse hepatocytes predicts clinical outcome in human cancer. Hepatology 2008; 47: 2059-67.
-
(2008)
Hepatology
, vol.47
, pp. 2059-2067
-
-
Coulouarn, C.1
-
4
-
-
33645742425
-
A novel prognostic subtype of human hepatocellular carcinoma derived from hepatic progenitor cells
-
Lee JS, Heo J, Libbrecht L, Chu IS, Kaposi-Novak P, Calvisi DF, Mikaelyan A, Roberts LR, Demetris AJ, Sun Z, Nevens F, Roskams T, Thorgeirsson SS. A novel prognostic subtype of human hepatocellular carcinoma derived from hepatic progenitor cells. Nat Med 2006; 12: 410-6.
-
(2006)
Nat Med
, vol.12
, pp. 410-416
-
-
Lee, J.S.1
Heo, J.2
Libbrecht, L.3
Chu, I.S.4
Kaposi-Novak, P.5
Calvisi, D.F.6
Mikaelyan, A.7
Roberts, L.R.8
Demetris, A.J.9
Sun, Z.10
Nevens, F.11
Roskams, T.12
Thorgeirsson, S.S.13
-
5
-
-
71849115857
-
Genome-wide DNA methylation profiles in liver tissue at the precancerous stage and in hepatocellular carcinoma
-
Arai E, Ushijima S, Gotoh M, Ojima H, Kosuge T, Hosoda F, Shibata T, Kondo T, Yokoi S, Imoto I, Inazawa J, Hirohashi S, Kanai Y. Genome-wide DNA methylation profiles in liver tissue at the precancerous stage and in hepatocellular carcinoma. Int J Cancer 2009; 125: 2854-62.
-
(2009)
Int J Cancer
, vol.125
, pp. 2854-2862
-
-
Arai, E.1
Ushijima, S.2
Gotoh, M.3
Ojima, H.4
Kosuge, T.5
Hosoda, F.6
Shibata, T.7
Kondo, T.8
Yokoi, S.9
Imoto, I.10
Inazawa, J.11
Hirohashi, S.12
Kanai, Y.13
-
6
-
-
77956607702
-
Identification of novel methylation markers in hepatocellular carcinoma using a methylation array
-
Shin SH, Kim BH, Jang JJ, Suh KS, Kang GH. Identification of novel methylation markers in hepatocellular carcinoma using a methylation array. J Korean Med Sci 2010; 25: 1152-9.
-
(2010)
J Korean Med Sci
, vol.25
, pp. 1152-1159
-
-
Shin, S.H.1
Kim, B.H.2
Jang, J.J.3
Suh, K.S.4
Kang, G.H.5
-
7
-
-
78649991362
-
Sulfatase 1 and sulfatase 2 in hepatocellular carcinoma: associated signaling pathways, tumor phenotypes, and survival
-
Yang JD, Sun Z, Hu C, Lai J, Dove R, Nakamura I, Lee JS, Thorgeirsson SS, Kang KJ, Chu IS, Roberts LR. Sulfatase 1 and sulfatase 2 in hepatocellular carcinoma: associated signaling pathways, tumor phenotypes, and survival. Genes Chromosomes Cancer 2011; 50: 122-35
-
(2011)
Genes Chromosomes Cancer
, vol.50
, pp. 122-135
-
-
Yang, J.D.1
Sun, Z.2
Hu, C.3
Lai, J.4
Dove, R.5
Nakamura, I.6
Lee, J.S.7
Thorgeirsson, S.S.8
Kang, K.J.9
Chu, I.S.10
Roberts, L.R.11
-
8
-
-
33747822630
-
Illumina universal bead arrays
-
Fan JB, Gunderson KL, Bibikova M, Yeakley JM, Chen J, Wickham Garcia E, Lebruska LL, Laurent M, Shen R, Barker D. Illumina universal bead arrays. Methods Enzymol 2006; 410: 57-73.
-
(2006)
Methods Enzymol
, vol.410
, pp. 57-73
-
-
Fan, J.B.1
Gunderson, K.L.2
Bibikova, M.3
Yeakley, J.M.4
Chen, J.5
Wickham Garcia, E.6
Lebruska, L.L.7
Laurent, M.8
Shen, R.9
Barker, D.10
-
9
-
-
79952038728
-
The tumor microenvironment in hepatocellular carcinoma: current status and therapeutic targets
-
Yang JD, Nakamura I, Roberts LR. The tumor microenvironment in hepatocellular carcinoma: current status and therapeutic targets. Semin Cancer Biol 2011; 21: 35-43.
-
(2011)
Semin Cancer Biol
, vol.21
, pp. 35-43
-
-
Yang, J.D.1
Nakamura, I.2
Roberts, L.R.3
-
11
-
-
34547440248
-
p53 downstream target DDA3 is a novel microtubule-associated protein that interacts with end-binding protein EB3 and activates beta-catenin pathway
-
Hsieh PC, Chang JC, Sun WT, Hsieh SC, Wang MC, Wang FF. p53 downstream target DDA3 is a novel microtubule-associated protein that interacts with end-binding protein EB3 and activates beta-catenin pathway. Oncogene 2007; 26: 4928-40.
-
(2007)
Oncogene
, vol.26
, pp. 4928-4940
-
-
Hsieh, P.C.1
Chang, J.C.2
Sun, W.T.3
Hsieh, S.C.4
Wang, M.C.5
Wang, F.F.6
-
12
-
-
52949152857
-
p53 target DDA3 binds ASPP2 and inhibits its stimulation on p53-mediated BAX activation
-
Sun WT, Hsieh PC, Chiang ML, Wang MC, Wang FF p53 target DDA3 binds ASPP2 and inhibits its stimulation on p53-mediated BAX activation. Biochem Biophys Res Commun 2008; 376: 395-8.
-
(2008)
Biochem Biophys Res Commun
, vol.376
, pp. 395-398
-
-
Sun, W.T.1
Hsieh, P.C.2
Chiang, M.L.3
Wang, M.C.4
Wang, F.F.5
-
13
-
-
34548074239
-
DNA methyltransferase expression and DNA methylation in human hepatocellular carcinoma and their clinicopathological correlation
-
Oh BK, Kim H, Park HJ, Shim YH, Choi J, Park C, Park YN. DNA methyltransferase expression and DNA methylation in human hepatocellular carcinoma and their clinicopathological correlation. Int J Mol Med 2007; 20: 65-73.
-
(2007)
Int J Mol Med
, vol.20
, pp. 65-73
-
-
Oh, B.K.1
Kim, H.2
Park, H.J.3
Shim, Y.H.4
Choi, J.5
Park, C.6
Park, Y.N.7
-
14
-
-
33845303143
-
Frequent epigenetic inactivation of spleen tyrosine kinase gene in human hepatocellular carcinoma
-
Yuan Y, Wang J, Li J, Wang L, Li M, Yang Z, Zhang C, Dai JL. Frequent epigenetic inactivation of spleen tyrosine kinase gene in human hepatocellular carcinoma. Clin Cancer Res 2006; 12: 6687-95.
-
(2006)
Clin Cancer Res
, vol.12
, pp. 6687-6695
-
-
Yuan, Y.1
Wang, J.2
Li, J.3
Wang, L.4
Li, M.5
Yang, Z.6
Zhang, C.7
Dai, J.L.8
-
15
-
-
54749135818
-
Cytoglobin, the newest member of the globin family, functions as a tumor suppressor gene
-
Shivapurkar N, Stastny V, Okumura N, Girard L, Xie Y, Prinsen C, Thunnissen FB, Wistuba II, Czerniak B, Frenkel E, Roth JA, Liloglou T, Xinarianos G, Field JK, Minna JD, Gazdar AF. Cytoglobin, the newest member of the globin family, functions as a tumor suppressor gene. Cancer Res 2008; 68: 7448-56.
-
(2008)
Cancer Res
, vol.68
, pp. 7448-7456
-
-
Shivapurkar, N.1
Stastny, V.2
Okumura, N.3
Girard, L.4
Xie, Y.5
Prinsen, C.6
Thunnissen, F.B.7
Wistuba, I.I.8
Czerniak, B.9
Frenkel, E.10
Roth, J.A.11
Liloglou, T.12
Xinarianos, G.13
Field, J.K.14
Minna, J.D.15
Gazdar, A.F.16
-
16
-
-
56549090632
-
Localization and expression pattern of cytoglobin in carbon tetrachloride-induced liver fibrosis
-
Man KN, Philipsen S, Tan-Un KC. Localization and expression pattern of cytoglobin in carbon tetrachloride-induced liver fibrosis. Toxicol Lett 2008; 183: 36-44.
-
(2008)
Toxicol Lett
, vol.183
, pp. 36-44
-
-
Man, K.N.1
Philipsen, S.2
Tan-Un, K.C.3
-
17
-
-
33646888232
-
Cytoglobin overexpression protects against damage-induced fibrosis
-
Xu R, Harrison PM, Chen M, Li L, Tsui TY, Fung PC, Cheung PT, Wang G, Li H, Diao Y, Krissansen GW, Xu S, Farzaneh F. Cytoglobin overexpression protects against damage-induced fibrosis. Mol Ther 2006; 13: 1093-100.
-
(2006)
Mol Ther
, vol.13
, pp. 1093-1100
-
-
Xu, R.1
Harrison, P.M.2
Chen, M.3
Li, L.4
Tsui, T.Y.5
Fung, P.C.6
Cheung, P.T.7
Wang, G.8
Li, H.9
Diao, Y.10
Krissansen, G.W.11
Xu, S.12
Farzaneh, F.13
-
18
-
-
27744571741
-
Downregulation of human kallikrein 10 (KLK10/NES1) by CpG island hypermethylation in breast, ovarian and prostate cancers
-
Sidiropoulos M, Pampalakis G, Sotiropoulou G, Katsaros D, Diamandis EP. Downregulation of human kallikrein 10 (KLK10/NES1) by CpG island hypermethylation in breast, ovarian and prostate cancers. Tumour Biol 2005; 26: 324-36.
-
(2005)
Tumour Biol
, vol.26
, pp. 324-336
-
-
Sidiropoulos, M.1
Pampalakis, G.2
Sotiropoulou, G.3
Katsaros, D.4
Diamandis, E.P.5
-
19
-
-
66149102406
-
Kallikrein 10 (KLK10) methylation as a novel prognostic biomarker in early breast cancer
-
Kioulafa M, Kaklamanis L, Stathopoulos E, Mavroudis D, Georgoulias V, Lianidou ES. Kallikrein 10 (KLK10) methylation as a novel prognostic biomarker in early breast cancer. Ann Oncol 2009; 20: 1020-5.
-
(2009)
Ann Oncol
, vol.20
, pp. 1020-1025
-
-
Kioulafa, M.1
Kaklamanis, L.2
Stathopoulos, E.3
Mavroudis, D.4
Georgoulias, V.5
Lianidou, E.S.6
-
20
-
-
70350236515
-
Aberrant DNA methylation profile and frequent methylation of KLK10 and OXGR1 genes in hepatocellular carcinoma
-
Lu CY, Hsieh SY, Lu YJ, Wu CS, Chen LC, Lo SJ, Wu CT, Chou MY, Huang TH, Chang YS. Aberrant DNA methylation profile and frequent methylation of KLK10 and OXGR1 genes in hepatocellular carcinoma. Genes Chromosomes Cancer 2009; 48: 1057-68.
-
(2009)
Genes Chromosomes Cancer
, vol.48
, pp. 1057-1068
-
-
Lu, C.Y.1
Hsieh, S.Y.2
Lu, Y.J.3
Wu, C.S.4
Chen, L.C.5
Lo, S.J.6
Wu, C.T.7
Chou, M.Y.8
Huang, T.H.9
Chang, Y.S.10
-
21
-
-
77449136807
-
Complement factor H is expressed in adipose tissue in association with insulin resistance
-
Moreno-Navarrete JM, Martínez-Barricarte R, Catalán V, Sabater M, Gómez-Ambrosi J, Ortega FJ, Ricart W, Blüher M, Frühbeck G, Rodríguez de Cordoba S, Fernández-Real JM. Complement factor H is expressed in adipose tissue in association with insulin resistance. Diabetes 2010; 59: 200-9.
-
(2010)
Diabetes
, vol.59
, pp. 200-209
-
-
Moreno-Navarrete, J.M.1
Martínez-Barricarte, R.2
Catalán, V.3
Sabater, M.4
Gómez-Ambrosi, J.5
Ortega, F.J.6
Ricart, W.7
Blüher, M.8
Frühbeck, G.9
Rodríguez de Cordoba, S.10
Fernández-Real, J.M.11
-
22
-
-
42149130812
-
Acquisition of biologically relevant gene expression data by Affymetrix microarray analysis of archival formalin-fixed paraffin-embedded tumours
-
Linton KM, Hey Y, Saunders E, Jeziorska M, Denton J, Wilson CL, Swindell R, Dibben S, Miller CJ, Pepper SD, Radford JA, Freemont AJ. Acquisition of biologically relevant gene expression data by Affymetrix microarray analysis of archival formalin-fixed paraffin-embedded tumours. Br J Cancer 2008; 98: 1403-14.
-
(2008)
Br J Cancer
, vol.98
, pp. 1403-1414
-
-
Linton, K.M.1
Hey, Y.2
Saunders, E.3
Jeziorska, M.4
Denton, J.5
Wilson, C.L.6
Swindell, R.7
Dibben, S.8
Miller, C.J.9
Pepper, S.D.10
Radford, J.A.11
Freemont, A.J.12
-
23
-
-
0033544724
-
The DNA double-strand break repair gene hMRE11 is mutated in individuals with an ataxia-telangiectasia-like disorder
-
Stewart GS, Maser RS, Stankovic T, Bressan DA, Kaplan MI, Jaspers NG, Raams A, Byrd PJ, Petrini JH, Taylor AM. The DNA double-strand break repair gene hMRE11 is mutated in individuals with an ataxia-telangiectasia-like disorder. Cell 1999; 99: 577-87.
-
(1999)
Cell
, vol.99
, pp. 577-587
-
-
Stewart, G.S.1
Maser, R.S.2
Stankovic, T.3
Bressan, D.A.4
Kaplan, M.I.5
Jaspers, N.G.6
Raams, A.7
Byrd, P.J.8
Petrini, J.H.9
Taylor, A.M.10
-
24
-
-
56649086648
-
Aberrations of the MRE11-RAD50-NBS1 DNA damage sensor complex in human breast cancer: MRE11 as a candidate familial cancer-predisposing gene
-
Bartkova J, Tommiska J, Oplustilova L, Aaltonen K, Tamminen A, Heikkinen T, Mistrik M, Aittomäki K, Blomqvist C, Heikkilä P, Lukas J, Nevanlinna H, Bartek J. Aberrations of the MRE11-RAD50-NBS1 DNA damage sensor complex in human breast cancer: MRE11 as a candidate familial cancer-predisposing gene. Mol Oncol 2008; 2: 296-316.
-
(2008)
Mol Oncol
, vol.2
, pp. 296-316
-
-
Bartkova, J.1
Tommiska, J.2
Oplustilova, L.3
Aaltonen, K.4
Tamminen, A.5
Heikkinen, T.6
Mistrik, M.7
Aittomäki, K.8
Blomqvist, C.9
Heikkilä, P.10
Lukas, J.11
Nevanlinna, H.12
Bartek, J.13
-
25
-
-
77952040472
-
LC3A-positive light microscopy detected patterns of autophagy and prognosis in operable breast carcinomas
-
Sivridis E, Koukourakis MI, Zois CE, Ledaki I, Ferguson DJ, Harris AL, Gatter KC, Giatromanolaki A. LC3A-positive light microscopy detected patterns of autophagy and prognosis in operable breast carcinomas. Am J Pathol 2010; 176: 2477-89.
-
(2010)
Am J Pathol
, vol.176
, pp. 2477-2489
-
-
Sivridis, E.1
Koukourakis, M.I.2
Zois, C.E.3
Ledaki, I.4
Ferguson, D.J.5
Harris, A.L.6
Gatter, K.C.7
Giatromanolaki, A.8
-
26
-
-
78650825936
-
Autophagy in endometrial carcinomas and prognostic relevance of 'stone-like' structures (SLS): what is destined for the atypical endometrial hyperplasia?
-
Sivridis E, Giatromanolaki A, Liberis V, Koukourakis MI. Autophagy in endometrial carcinomas and prognostic relevance of 'stone-like' structures (SLS): what is destined for the atypical endometrial hyperplasia? Autophagy 2011; 7: 74-82.
-
(2011)
Autophagy
, vol.7
, pp. 74-82
-
-
Sivridis, E.1
Giatromanolaki, A.2
Liberis, V.3
Koukourakis, M.I.4
-
27
-
-
33846821794
-
Myosin 1E interacts with synaptojanin-1 and dynamin and is involved in endocytosis
-
Krendel M, Osterweil EK, Mooseker MS. Myosin 1E interacts with synaptojanin-1 and dynamin and is involved in endocytosis. FEBS Lett 2007; 581: 644-50.
-
(2007)
FEBS Lett
, vol.581
, pp. 644-650
-
-
Krendel, M.1
Osterweil, E.K.2
Mooseker, M.S.3
-
28
-
-
34249019902
-
Analysis of the linkage of MYRIP and MYO7A to melanosomes by RAB27A in retinal pigment epithelial cells
-
Klomp AE, Teofilo K, Legacki E, Williams DS. Analysis of the linkage of MYRIP and MYO7A to melanosomes by RAB27A in retinal pigment epithelial cells. Cell Motil Cytoskeleton 2007; 64: 474-87.
-
(2007)
Cell Motil Cytoskeleton
, vol.64
, pp. 474-487
-
-
Klomp, A.E.1
Teofilo, K.2
Legacki, E.3
Williams, D.S.4
-
29
-
-
66549127369
-
Rab27a and MyRIP regulate the amount and multimeric state of VWF released from endothelial cells
-
Nightingale TD, Pattni K, Hume AN, Seabra MC, Cutler DF. Rab27a and MyRIP regulate the amount and multimeric state of VWF released from endothelial cells. Blood 2009; 113: 5010-8.
-
(2009)
Blood
, vol.113
, pp. 5010-5018
-
-
Nightingale, T.D.1
Pattni, K.2
Hume, A.N.3
Seabra, M.C.4
Cutler, D.F.5
-
30
-
-
27144528747
-
Human mitochondrial complex I assembly is mediated by NDUFAF1
-
Vogel RO, Janssen RJ, Ugalde C, Grovenstein M, Huijbens RJ, Visch HJ, van den Heuvel LP, Willems PH, Zeviani M, Smeitink JA, Nijtmans LG. Human mitochondrial complex I assembly is mediated by NDUFAF1. FEBS J 2005; 272: 5317-26.
-
(2005)
FEBS J
, vol.272
, pp. 5317-5326
-
-
Vogel, R.O.1
Janssen, R.J.2
Ugalde, C.3
Grovenstein, M.4
Huijbens, R.J.5
Visch, H.J.6
van den Heuvel, L.P.7
Willems, P.H.8
Zeviani, M.9
Smeitink, J.A.10
Nijtmans, L.G.11
|