Dancing through life: Molecular dynamics simulations and network-centric modeling of allosteric mechanisms in Hsp70 and Hsp110 chaperone proteins

PLoS ONE

Volumn 10, Issue 11, 2015, Pages

  Stetz, Gabrielle ^a   Verkhivker, Gennady M ^a  

^a CHAPMAN UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

HEAT SHOCK PROTEIN 110; HEAT SHOCK PROTEIN 70; PROTEIN DNAK; PEPTIDE;

ALLOSTERISM; ARTICLE; CALCULATION; CONFORMATIONAL TRANSITION; CONTROLLED STUDY; CRYSTAL STRUCTURE; ENTROPY; HYDROPHOBICITY; MOLECULAR DOCKING; MOLECULAR DYNAMICS; MOLECULAR INTERACTION; MOLECULAR MODEL; MOLECULAR PROBE; MUTATIONAL ANALYSIS; NONHUMAN; NUCLEOTIDE BINDING SITE; PHASE TRANSITION; PREVALENCE; PROTEIN DOMAIN; PROTEIN STABILITY; RESIDUE ANALYSIS; SENSITIVITY ANALYSIS; STRUCTURE ACTIVITY RELATION; STRUCTURE ANALYSIS; ALLOSTERIC SITE; CHEMISTRY; METABOLISM; PROTEIN CONFORMATION; PROTEIN FOLDING;

ALLOSTERIC REGULATION; ALLOSTERIC SITE; ENTROPY; HSP110 HEAT-SHOCK PROTEINS; HSP70 HEAT-SHOCK PROTEINS; MODELS, MOLECULAR; MOLECULAR DYNAMICS SIMULATION; PEPTIDES; PROTEIN CONFORMATION; PROTEIN FOLDING; PROTEIN STABILITY;

EID: 84957539705     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0143752     Document Type: Article

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