Role of Hsp70 ATPase domain intrinsic dynamics and sequence evolution in enabling its functional interactions with NEFs

PLoS Computational Biology

Volumn 6, Issue 9, 2010, Pages

  Liu, Ying ^a   Gierasch, Lila M ^b   Bahar, Ivet ^a  

^a UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF MASSACHUSETTS   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

COMPLEX NETWORKS; DYNAMICS; NUCLEOTIDES;

ATPASE DOMAIN; CO-EVOLUTION; COLLECTIVE DYNAMICS; CONSERVED RESIDUES; ELASTIC NETWORK MODELS; EVOLUTIONARY TRACES; FUNCTIONAL INTERACTION; KEY RESIDUES; MOLECULAR CHAPERONES; NUCLEOTIDE-EXCHANGE FACTOR;

STRUCTURAL DYNAMICS;

ADENOSINE TRIPHOSPHATASE; APYRASE; BAG 1 PROTEIN; GUANINE NUCLEOTIDE EXCHANGE FACTOR; HEAT SHOCK PROTEIN 70; HEAT SHOCK PROTEIN BP1 PROTEIN; PROTEIN GRPE; PROTEIN SSE 1; UNCLASSIFIED DRUG;

ALLOSTERISM; AMINO ACID SEQUENCE; ANISOTROPY; ARTICLE; BETA SHEET; BINDING SITE; COMPLEX FORMATION; CONTROLLED STUDY; ENZYME ACTIVITY; NONHUMAN; NUCLEOTIDE BINDING SITE; PHYLOGENY; PROTEIN DOMAIN; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; PROTEIN STRUCTURE; SEQUENCE ALIGNMENT; SEQUENCE ANALYSIS;

EID: 78049433050     PISSN: 1553734X     EISSN: 15537358     Source Type: Journal    
DOI: 10.1371/journal.pcbi.1000931     Document Type: Article

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