Allostery and the monod-wyman-changeux model after 50 years

Annual Review of Biophysics

Volumn 41, Issue 1, 2012, Pages 103-133

  Changeux, Jean Pierre ^a  

^a CNRS   (France)

Author keywords

Allosteric proteins; Conformational selection versus induced fit; Drug design; Receptor diseases; Signal transduction

Indexed keywords

BACTERIAL ENZYME; CELL NUCLEUS RECEPTOR; G PROTEIN COUPLED RECEPTOR; GLUTAMATE RECEPTOR; HEMOGLOBIN; ION CHANNEL; MEMBRANE PROTEIN; NEUROTRANSMITTER; NICOTINIC RECEPTOR; OLIGOMER; PURINERGIC P2X RECEPTOR; REGULATOR PROTEIN; TOLL LIKE RECEPTOR; TYROSINE KINASE RECEPTOR;

ALLOSTERISM; ANALYTICAL PARAMETERS; BINDING SITE; CHEMICAL STRUCTURE; CONFORMATIONAL TRANSITION; INTRACELLULAR SIGNALING; MONOD WYMAN CHANGEUX; NONHUMAN; PRIORITY JOURNAL; PROTEIN LOCALIZATION; REVIEW; SIGNAL TRANSDUCTION;

ALLOSTERIC REGULATION; ANIMALS; BACTERIA; HEMOGLOBINS; HUMANS; LIGANDS; MEMBRANE PROTEINS; MODELS, BIOLOGICAL; SIGNAL TRANSDUCTION;

BACTERIA (MICROORGANISMS);

EID: 84861219631     PISSN: 1936122X     EISSN: 19361238     Source Type: Book Series    
DOI: 10.1146/annurev-biophys-050511-102222     Document Type: Review

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