Amide hydrogen exchange reveals conformational changes in Hsp70 chaperones important for allosteric regulation

Journal of Biological Chemistry

Volumn 281, Issue 24, 2006, Pages 16493-16501

  Rist, Wolfgang ^a,b   Graf, Christian ^a   Bukau, Bernd ^a   Mayer, Matthias P ^a  

^a UNIVERSITY OF HEIDELBERG   (Germany)

^b BOEHRINGER INGELHEIM PHARMA GMBH AND CO KG   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINETRIPHOSPHATE; BINDING ENERGY; BIOCHEMISTRY; CONFORMATIONS; ESCHERICHIA COLI; MASS SPECTROMETRY; NUCLEIC ACIDS; PROTEINS;

AMIDE HYDROGEN; CONFORMATIONAL CHANGES; NUCLEOTIDE-BINDING (NBD); SUBSTRATE-BINDING DOMAINS (SBD);

NITROGEN COMPOUNDS;

ADENOSINE TRIPHOSPHATE; AMIDE; CHAPERONE; ESCHERICHIA COLI PROTEIN; HEAT SHOCK PROTEIN 70; HYDROGEN; NUCLEOTIDE; PROTEIN DERIVATIVE; PROTEIN DNAK; SOLVENT;

ALLOSTERISM; ALPHA HELIX; ARTICLE; BETA SHEET; CONFORMATIONAL TRANSITION; ESCHERICHIA COLI; MASS SPECTROMETRY; PRIORITY JOURNAL; PROTEIN BINDING;

ADENOSINE TRIPHOSPHATE; ALLOSTERIC REGULATION; ALLOSTERIC SITE; AMINO ACID SEQUENCE; ESCHERICHIA COLI; ESCHERICHIA COLI PROTEINS; HSP70 HEAT-SHOCK PROTEINS; HYDROGEN; MODELS, MOLECULAR; MOLECULAR CONFORMATION; MOLECULAR SEQUENCE DATA; PROTEIN CONFORMATION; PROTEIN STRUCTURE, TERTIARY; SOLVENTS;

ESCHERICHIA COLI;

EID: 33745183353     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M600847200     Document Type: Article

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