Residue centrality, functionally important residues, and active site shape: Analysis of enzyme and non-enzyme families

Protein Science

Volumn 15, Issue 9, 2006, Pages 2120-2128

  Del Sol, Antonio ^a   Fujihashi, Hirotomo ^a   Amoros, Dolors ^a   Nussinov, Ruth ^b,c  

^a FUJIREBIO INC   (Japan)

^b SAIC FREDERICK INC   (United States)

^c TEL AVIV UNIVERSITY   (Israel)

Author keywords

Active sites; Characteristic path length; Closeness centrality; Conserved central positions; Network

Indexed keywords

ENZYME; PROTEIN DERIVATIVE;

ARTICLE; ATOM; BINDING SITE; ENZYME ACTIVE SITE; ENZYME ANALYSIS; ENZYME BINDING; ENZYME STRUCTURE; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN FOLDING; PROTEIN PROTEIN INTERACTION; RESIDUE ANALYSIS;

AMINO ACID SEQUENCE; BINDING SITES; ENZYMES; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; PROTEIN FOLDING; PROTEIN STRUCTURE, TERTIARY; SENSITIVITY AND SPECIFICITY; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 33748207211     PISSN: 09618368     EISSN: 1469896X     Source Type: Journal    
DOI: 10.1110/ps.062249106     Document Type: Article

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