-
1
-
-
0038218405
-
Sphingosine-1-phosphate: An enigmatic signalling lipid
-
S. Spiegel, and S. Milstien Sphingosine-1-phosphate: an enigmatic signalling lipid Nat. Rev. Mol. Cell Biol. 4 5 2003 397 407
-
(2003)
Nat. Rev. Mol. Cell Biol.
, vol.4
, Issue.5
, pp. 397-407
-
-
Spiegel, S.1
Milstien, S.2
-
2
-
-
84930541286
-
Sphingosine1-phosphate signaling at the blood-brain barrier
-
B. Prager, S.F. Spampinato, and R.M. Ransohoff Sphingosine1-phosphate signaling at the blood-brain barrier Trends Mol. Med. 21 6 2015 354 363
-
(2015)
Trends Mol. Med.
, vol.21
, Issue.6
, pp. 354-363
-
-
Prager, B.1
Spampinato, S.F.2
Ransohoff, R.M.3
-
3
-
-
84903955408
-
Sphingosine-1-phosphate: Boon and bane for the brain
-
G. van Echten-Deckert, and et al. Sphingosine-1-phosphate: boon and bane for the brain Cell Physiol. Biochem. 34 1 2014 148 157
-
(2014)
Cell Physiol. Biochem.
, vol.34
, Issue.1
, pp. 148-157
-
-
Van Echten-Deckert, G.1
-
4
-
-
84921380792
-
Drugging sphingosine kinases
-
W.L. Santos, and K.R. Lynch Drugging sphingosine kinases ACS Chem. Biol. 10 1 2015 225 233
-
(2015)
ACS Chem. Biol.
, vol.10
, Issue.1
, pp. 225-233
-
-
Santos, W.L.1
Lynch, K.R.2
-
5
-
-
84868569679
-
Post-translational regulation of sphingosine kinases
-
H. Chan, and S.M. Pitson Post-translational regulation of sphingosine kinases Biochim. Biophys. Acta 1831 1 2013 147 156
-
(2013)
Biochim. Biophys. Acta
, vol.1831
, Issue.1
, pp. 147-156
-
-
Chan, H.1
Pitson, S.M.2
-
6
-
-
84898897679
-
Sphingosine kinases/sphingosine-1-phosphate and death signalling in APP-transfected cells
-
M. Gassowska, and et al. Sphingosine kinases/sphingosine-1-phosphate and death signalling in APP-transfected cells Neurochem. Res. 39 4 2014 645 652
-
(2014)
Neurochem. Res.
, vol.39
, Issue.4
, pp. 645-652
-
-
Gassowska, M.1
-
7
-
-
77950519513
-
Expression and regulation of enzymes in the ceramide metabolic pathway in human retinal pigment epithelial cells and their relevance to retinal degeneration
-
D. Zhu, and et al. Expression and regulation of enzymes in the ceramide metabolic pathway in human retinal pigment epithelial cells and their relevance to retinal degeneration Vision Res. 50 7 2010 643 651
-
(2010)
Vision Res.
, vol.50
, Issue.7
, pp. 643-651
-
-
Zhu, D.1
-
8
-
-
77953966511
-
Sphingosine 1-phosphate and cancer
-
N.J. Pyne, and S. Pyne Sphingosine 1-phosphate and cancer Nat. Rev. Cancer 10 7 2010 489 503
-
(2010)
Nat. Rev. Cancer
, vol.10
, Issue.7
, pp. 489-503
-
-
Pyne, N.J.1
Pyne, S.2
-
9
-
-
35948936347
-
Involvement of sphingosine kinase 2 in p53-independent induction of p21 by the chemotherapeutic drug doxorubicin
-
H.M. Sankala, and et al. Involvement of sphingosine kinase 2 in p53-independent induction of p21 by the chemotherapeutic drug doxorubicin Cancer Res. 67 21 2007 10466 10474
-
(2007)
Cancer Res.
, vol.67
, Issue.21
, pp. 10466-10474
-
-
Sankala, H.M.1
-
10
-
-
0141924852
-
Sphingosine kinase type 2 is a putative BH3-only protein that induces apoptosis
-
H. Liu, and et al. Sphingosine kinase type 2 is a putative BH3-only protein that induces apoptosis J. Biol. Chem. 278 41 2003 40330 40336
-
(2003)
J. Biol. Chem.
, vol.278
, Issue.41
, pp. 40330-40336
-
-
Liu, H.1
-
11
-
-
84886101285
-
Roles, regulation and inhibitors of sphingosine kinase 2
-
H.A. Neubauer, and S.M. Pitson Roles, regulation and inhibitors of sphingosine kinase 2 FEBS J. 280 21 2013 5317 5336
-
(2013)
FEBS J.
, vol.280
, Issue.21
, pp. 5317-5336
-
-
Neubauer, H.A.1
Pitson, S.M.2
-
12
-
-
0028956049
-
Involvement of a pertussis toxin-sensitive G protein in the mitogenic signaling pathways of sphingosine 1- phosphate
-
K.A. Goodemote, and et al. Involvement of a pertussis toxin-sensitive G protein in the mitogenic signaling pathways of sphingosine 1- phosphate J. Biol. Chem. 270 17 1995 10272 10277
-
(1995)
J. Biol. Chem.
, vol.270
, Issue.17
, pp. 10272-10277
-
-
Goodemote, K.A.1
-
13
-
-
58849083220
-
The sphingolipid transporter spns2 functions in migration of zebrafish myocardial precursors
-
A. Kawahara, and et al. The sphingolipid transporter spns2 functions in migration of zebrafish myocardial precursors Science 323 5913 2009 524 527
-
(2009)
Science
, vol.323
, Issue.5913
, pp. 524-527
-
-
Kawahara, A.1
-
14
-
-
33750832270
-
Role of ABCC1 in export of sphingosine-1-phosphate from mast cells
-
P. Mitra, and et al. Role of ABCC1 in export of sphingosine-1-phosphate from mast cells Proc. Natl. Acad. Sci. U. S. A. 103 44 2006 16394 16399
-
(2006)
Proc. Natl. Acad. Sci. U. S. A.
, vol.103
, Issue.44
, pp. 16394-16399
-
-
Mitra, P.1
-
15
-
-
84904600448
-
Lysophospholipid receptor nomenclature review: IUPHAR Review 8
-
Y. Kihara, and et al. Lysophospholipid receptor nomenclature review: IUPHAR Review 8 Br. J. Pharmacol. 171 15 2014 3575 3594
-
(2014)
Br. J. Pharmacol.
, vol.171
, Issue.15
, pp. 3575-3594
-
-
Kihara, Y.1
-
16
-
-
84889670659
-
Sphingosine-1-phosphate receptor 2
-
M. Adada, and et al. Sphingosine-1-phosphate receptor 2 FEBS J. 280 24 2013 6354 6366
-
(2013)
FEBS J.
, vol.280
, Issue.24
, pp. 6354-6366
-
-
Adada, M.1
-
17
-
-
84857254248
-
Crystal structure of a lipid G protein-coupled receptor
-
M.A. Hanson, and et al. Crystal structure of a lipid G protein-coupled receptor Science 335 6070 2012 851 855
-
(2012)
Science
, vol.335
, Issue.6070
, pp. 851-855
-
-
Hanson, M.A.1
-
18
-
-
84930900389
-
SPHK1 inhibitor suppresses cell proliferation and invasion associated with the inhibition of NF-kappaB pathway in hepatocellular carcinoma
-
Z. Zhang, and et al. SPHK1 inhibitor suppresses cell proliferation and invasion associated with the inhibition of NF-kappaB pathway in hepatocellular carcinoma Tumour Biol. 36 3 2015 1503 1509
-
(2015)
Tumour Biol.
, vol.36
, Issue.3
, pp. 1503-1509
-
-
Zhang, Z.1
-
19
-
-
77949748845
-
Pharmacology and antitumor activity of ABC294640, a selective inhibitor of sphingosine kinase-2
-
K.J. French, and et al. Pharmacology and antitumor activity of ABC294640, a selective inhibitor of sphingosine kinase-2 J. Pharmacol. Exp. Ther. 333 1 2010 129 139
-
(2010)
J. Pharmacol. Exp. Ther.
, vol.333
, Issue.1
, pp. 129-139
-
-
French, K.J.1
-
20
-
-
24344501665
-
Immunohistochemical distribution of sphingosine kinase 1 in normal and tumor lung tissue
-
K.R. Johnson, and et al. Immunohistochemical distribution of sphingosine kinase 1 in normal and tumor lung tissue J. Histochem. Cytochem. 53 9 2005 1159 1166
-
(2005)
J. Histochem. Cytochem.
, vol.53
, Issue.9
, pp. 1159-1166
-
-
Johnson, K.R.1
-
21
-
-
33749185077
-
Intracellular role for sphingosine kinase 1 in intestinal adenoma cell proliferation
-
M. Kohno, and et al. Intracellular role for sphingosine kinase 1 in intestinal adenoma cell proliferation Mol. Cell Biol. 26 19 2006 7211 7223
-
(2006)
Mol. Cell Biol.
, vol.26
, Issue.19
, pp. 7211-7223
-
-
Kohno, M.1
-
22
-
-
77953790503
-
An update on sphingosine-1-phosphate and other sphingolipid mediators
-
H. Fyrst, and J.D. Saba An update on sphingosine-1-phosphate and other sphingolipid mediators Nat. Chem. Biol. 6 7 2010 489 497
-
(2010)
Nat. Chem. Biol.
, vol.6
, Issue.7
, pp. 489-497
-
-
Fyrst, H.1
Saba, J.D.2
-
23
-
-
84894299478
-
Review: Novel insights into the regulation of vascular tone by sphingosine 1-phosphate
-
D. Kerage, D.N. Brindley, and D.G. Hemmings Review: novel insights into the regulation of vascular tone by sphingosine 1-phosphate Placenta 35 Suppl 2014 S86 S92
-
(2014)
Placenta
, vol.35
, pp. S86-S92
-
-
Kerage, D.1
Brindley, D.N.2
Hemmings, D.G.3
-
24
-
-
52949108813
-
The alliance of sphingosine-1-phosphate and its receptors in immunity
-
J. Rivera, R.L. Proia, and A. Olivera The alliance of sphingosine-1-phosphate and its receptors in immunity Nat. Rev. Immunol. 8 10 2008 753 763
-
(2008)
Nat. Rev. Immunol.
, vol.8
, Issue.10
, pp. 753-763
-
-
Rivera, J.1
Proia, R.L.2
Olivera, A.3
-
25
-
-
28544437478
-
Essential role for sphingosine kinases in neural and vascular development
-
K. Mizugishi, and et al. Essential role for sphingosine kinases in neural and vascular development Mol. Cell Biol. 25 24 2005 11113 11121
-
(2005)
Mol. Cell Biol.
, vol.25
, Issue.24
, pp. 11113-11121
-
-
Mizugishi, K.1
-
26
-
-
84903270821
-
Active, phosphorylated fingolimod inhibits histone deacetylases and facilitates fear extinction memory
-
N.C. Hait, and et al. Active, phosphorylated fingolimod inhibits histone deacetylases and facilitates fear extinction memory Nat. Neurosci. 17 7 2014 971 980
-
(2014)
Nat. Neurosci.
, vol.17
, Issue.7
, pp. 971-980
-
-
Hait, N.C.1
-
27
-
-
14844309632
-
Extracellular release of newly synthesized sphingosine-1-phosphate by cerebellar granule cells and astrocytes
-
V. Anelli, and et al. Extracellular release of newly synthesized sphingosine-1-phosphate by cerebellar granule cells and astrocytes J. Neurochem. 92 5 2005 1204 1215
-
(2005)
J. Neurochem.
, vol.92
, Issue.5
, pp. 1204-1215
-
-
Anelli, V.1
-
28
-
-
1042278008
-
Sphingosine-1-phosphate induces proliferation and morphological changes of neural progenitor cells
-
J. Harada, and et al. Sphingosine-1-phosphate induces proliferation and morphological changes of neural progenitor cells J. Neurochem. 88 4 2004 1026 1039
-
(2004)
J. Neurochem.
, vol.88
, Issue.4
, pp. 1026-1039
-
-
Harada, J.1
-
29
-
-
0141918792
-
Pharmacological characterization of lysophospholipid receptor signal transduction pathways in rat cerebrocortical astrocytes
-
T.S. Rao, and et al. Pharmacological characterization of lysophospholipid receptor signal transduction pathways in rat cerebrocortical astrocytes Brain Res. 990 1-2 2003 182 194
-
(2003)
Brain Res.
, vol.990
, Issue.1-2
, pp. 182-194
-
-
Rao, T.S.1
-
30
-
-
0346024177
-
Characterization of lysophosphatidic acid and sphingosine-1-phosphate-mediated signal transduction in rat cortical oligodendrocytes
-
N. Yu, and et al. Characterization of lysophosphatidic acid and sphingosine-1-phosphate-mediated signal transduction in rat cortical oligodendrocytes Glia 45 1 2004 17 27
-
(2004)
Glia
, vol.45
, Issue.1
, pp. 17-27
-
-
Yu, N.1
-
31
-
-
39049125218
-
FTY720 modulates human oligodendrocyte progenitor process extension and survival
-
V.E. Miron, and et al. FTY720 modulates human oligodendrocyte progenitor process extension and survival Ann. Neurol. 63 1 2008 61 71
-
(2008)
Ann. Neurol.
, vol.63
, Issue.1
, pp. 61-71
-
-
Miron, V.E.1
-
32
-
-
70350754356
-
Regulation of stem cell pluripotency and neural differentiation by lysophospholipids
-
S.M. Pitson, and A. Pebay Regulation of stem cell pluripotency and neural differentiation by lysophospholipids Neurosignals 17 4 2009 242 254
-
(2009)
Neurosignals
, vol.17
, Issue.4
, pp. 242-254
-
-
Pitson, S.M.1
Pebay, A.2
-
33
-
-
33846021925
-
Essential roles of sphingosine 1-phosphate/S1P1 receptor axis in the migration of neural stem cells toward a site of spinal cord injury
-
A. Kimura, and et al. Essential roles of sphingosine 1-phosphate/S1P1 receptor axis in the migration of neural stem cells toward a site of spinal cord injury Stem Cells 25 1 2007 115 124
-
(2007)
Stem Cells
, vol.25
, Issue.1
, pp. 115-124
-
-
Kimura, A.1
-
34
-
-
34247554847
-
Activation of sphingosine-1- phosphate receptor S1P5 inhibits oligodendrocyte progenitor migration
-
A.S. Novgorodov, and et al. Activation of sphingosine-1- phosphate receptor S1P5 inhibits oligodendrocyte progenitor migration FASEB J. 21 7 2007 1503 1514
-
(2007)
FASEB J.
, vol.21
, Issue.7
, pp. 1503-1514
-
-
Novgorodov, A.S.1
-
35
-
-
35348940243
-
Functional consequences of S1P receptor modulation in rat oligodendroglial lineage cells
-
C.G. Jung, and et al. Functional consequences of S1P receptor modulation in rat oligodendroglial lineage cells Glia 55 16 2007 1656 1667
-
(2007)
Glia
, vol.55
, Issue.16
, pp. 1656-1667
-
-
Jung, C.G.1
-
36
-
-
13844271705
-
Edg8/S1P5: An oligodendroglial receptor with dual function on process retraction and cell survival
-
C. Jaillard, and et al. Edg8/S1P5: an oligodendroglial receptor with dual function on process retraction and cell survival J. Neurosci. 25 6 2005 1459 1469
-
(2005)
J. Neurosci.
, vol.25
, Issue.6
, pp. 1459-1469
-
-
Jaillard, C.1
-
37
-
-
0029879915
-
Sphingosine-1-phosphate rapidly induces Rho-dependent neurite retraction: Action through a specific cell surface receptor
-
F.R. Postma, and et al. Sphingosine-1-phosphate rapidly induces Rho-dependent neurite retraction: action through a specific cell surface receptor EMBO J. 15 10 1996 2388 2392
-
(1996)
EMBO J.
, vol.15
, Issue.10
, pp. 2388-2392
-
-
Postma, F.R.1
-
38
-
-
0030780015
-
Involvement of sphingosine 1-phosphate in nerve growth factor-mediated neuronal survival and differentiation
-
L.C. Edsall, G.G. Pirianov, and S. Spiegel Involvement of sphingosine 1-phosphate in nerve growth factor-mediated neuronal survival and differentiation J. Neurosci. 17 18 1997 6952 6960
-
(1997)
J. Neurosci.
, vol.17
, Issue.18
, pp. 6952-6960
-
-
Edsall, L.C.1
Pirianov, G.G.2
Spiegel, S.3
-
39
-
-
3543132506
-
Differential transactivation of sphingosine-1-phosphate receptors modulates NGF-induced neurite extension
-
R.E. Toman, and et al. Differential transactivation of sphingosine-1-phosphate receptors modulates NGF-induced neurite extension J. Cell Biol. 166 3 2004 381 392
-
(2004)
J. Cell Biol.
, vol.166
, Issue.3
, pp. 381-392
-
-
Toman, R.E.1
-
40
-
-
0023950535
-
Suppression of nerve growth factor-directed neurite outgrowth in PC12 cells by sphingosine: An inhibitor of protein kinase C
-
F.L. Hall, and et al. Suppression of nerve growth factor-directed neurite outgrowth in PC12 cells by sphingosine: an inhibitor of protein kinase C J. Biol. Chem. 263 9 1988 4460 4466
-
(1988)
J. Biol. Chem.
, vol.263
, Issue.9
, pp. 4460-4466
-
-
Hall, F.L.1
-
41
-
-
0037440379
-
Sphingosine 1-phosphate induces the production of glial cell line-derived neurotrophic factor and cellular proliferation in astrocytes
-
K. Yamagata, and et al. Sphingosine 1-phosphate induces the production of glial cell line-derived neurotrophic factor and cellular proliferation in astrocytes Glia 41 2 2003 199 206
-
(2003)
Glia
, vol.41
, Issue.2
, pp. 199-206
-
-
Yamagata, K.1
-
42
-
-
80055006975
-
Sphingosine kinase 1/S1P pathway involvement in the GDNF-induced GAP43 transcription
-
M. Murakami, and et al. Sphingosine kinase 1/S1P pathway involvement in the GDNF-induced GAP43 transcription J. Cell Biochem. 112 11 2011 3449 3458
-
(2011)
J. Cell Biochem.
, vol.112
, Issue.11
, pp. 3449-3458
-
-
Murakami, M.1
-
43
-
-
0035824817
-
Depolarisation induces rapid and transient formation of intracellular sphingosine-1-phosphate
-
R. Alemany, and et al. Depolarisation induces rapid and transient formation of intracellular sphingosine-1-phosphate FEBS Lett. 509 2 2001 239 244
-
(2001)
FEBS Lett.
, vol.509
, Issue.2
, pp. 239-244
-
-
Alemany, R.1
-
44
-
-
34247552132
-
Involvement of sphingosine-1-phosphate in glutamate secretion in hippocampal neurons
-
T. Kajimoto, and et al. Involvement of sphingosine-1-phosphate in glutamate secretion in hippocampal neurons Mol. Cell Biol. 27 9 2007 3429 3440
-
(2007)
Mol. Cell Biol.
, vol.27
, Issue.9
, pp. 3429-3440
-
-
Kajimoto, T.1
-
45
-
-
79959989509
-
Endogenous sphingosine 1-phosphate regulates spontaneous glutamate release from mossy fiber terminals via S1P(3) receptors
-
T. Kanno, and T. Nishizaki Endogenous sphingosine 1-phosphate regulates spontaneous glutamate release from mossy fiber terminals via S1P(3) receptors Life Sci. 89 3-4 2011 137 140
-
(2011)
Life Sci.
, vol.89
, Issue.3-4
, pp. 137-140
-
-
Kanno, T.1
Nishizaki, T.2
-
46
-
-
67651171665
-
Sphingosine-1-phosphate receptors mediate neuromodulatory functions in the CNS
-
L.J. Sim-Selley, and et al. Sphingosine-1-phosphate receptors mediate neuromodulatory functions in the CNS J. Neurochem. 110 4 2009 1191 1202
-
(2009)
J. Neurochem.
, vol.110
, Issue.4
, pp. 1191-1202
-
-
Sim-Selley, L.J.1
-
47
-
-
84869221033
-
Sphingosine-1-phosphate receptors as emerging targets for treatment of pain
-
S.P. Welch, L.J. Sim-Selley, and D.E. Selley Sphingosine-1-phosphate receptors as emerging targets for treatment of pain Biochem. Pharmacol. 84 12 2012 1551 1562
-
(2012)
Biochem. Pharmacol.
, vol.84
, Issue.12
, pp. 1551-1562
-
-
Welch, S.P.1
Sim-Selley, L.J.2
Selley, D.E.3
-
48
-
-
78650176947
-
Regulation of synaptic strength by sphingosine 1-phosphate in the hippocampus
-
T. Kanno, and et al. Regulation of synaptic strength by sphingosine 1-phosphate in the hippocampus Neuroscience 171 4 2010 973 980
-
(2010)
Neuroscience
, vol.171
, Issue.4
, pp. 973-980
-
-
Kanno, T.1
-
49
-
-
0034887535
-
An essential role for the H218/AGR16/Edg-5/LP(B2) sphingosine 1-phosphate receptor in neuronal excitability
-
A.J. MacLennan, and et al. An essential role for the H218/AGR16/Edg-5/LP(B2) sphingosine 1-phosphate receptor in neuronal excitability Eur. J. Neurosci. 14 2 2001 203 209
-
(2001)
Eur. J. Neurosci.
, vol.14
, Issue.2
, pp. 203-209
-
-
Maclennan, A.J.1
-
50
-
-
33746850399
-
Sphingosine-1-phosphate via activation of a G-protein-coupled receptor(s) enhances the excitability of rat sensory neurons
-
Y.H. Zhang, and et al. Sphingosine-1-phosphate via activation of a G-protein-coupled receptor(s) enhances the excitability of rat sensory neurons J. Neurophysiol. 96 3 2006 1042 1052
-
(2006)
J. Neurophysiol.
, vol.96
, Issue.3
, pp. 1042-1052
-
-
Zhang, Y.H.1
-
51
-
-
84869208878
-
Regulation of autophagy and its associated cell death by sphingolipid rheostat: Reciprocal role of ceramide and sphingosine 1-phosphate in the mammalian target of rapamycin pathway
-
M. Taniguchi, and et al. Regulation of autophagy and its associated cell death by sphingolipid rheostat: reciprocal role of ceramide and sphingosine 1-phosphate in the mammalian target of rapamycin pathway J. Biol. Chem. 287 47 2012 39898 39910
-
(2012)
J. Biol. Chem.
, vol.287
, Issue.47
, pp. 39898-39910
-
-
Taniguchi, M.1
-
52
-
-
33646831810
-
Regulation of autophagy by sphingosine kinase 1 and its role in cell survival during nutrient starvation
-
G. Lavieu, and et al. Regulation of autophagy by sphingosine kinase 1 and its role in cell survival during nutrient starvation J. Biol. Chem. 281 13 2006 8518 8527
-
(2006)
J. Biol. Chem.
, vol.281
, Issue.13
, pp. 8518-8527
-
-
Lavieu, G.1
-
53
-
-
84894468110
-
Mitochondrial dysfunction contributes to neurodegeneration in multiple sclerosis
-
M.E. Witte, and et al. Mitochondrial dysfunction contributes to neurodegeneration in multiple sclerosis Trends Mol. Med. 20 3 2014 179 187
-
(2014)
Trends Mol. Med.
, vol.20
, Issue.3
, pp. 179-187
-
-
Witte, M.E.1
-
54
-
-
33750347347
-
Mitochondrial dysfunction and oxidative stress in neurodegenerative diseases
-
M.T. Lin, and M.F. Beal Mitochondrial dysfunction and oxidative stress in neurodegenerative diseases Nature 443 7113 2006 787 795
-
(2006)
Nature
, vol.443
, Issue.7113
, pp. 787-795
-
-
Lin, M.T.1
Beal, M.F.2
-
55
-
-
79551648970
-
Sphingosine-1-phosphate produced by sphingosine kinase 2 in mitochondria interacts with prohibitin 2 to regulate complex IV assembly and respiration
-
G.M. Strub, and et al. Sphingosine-1-phosphate produced by sphingosine kinase 2 in mitochondria interacts with prohibitin 2 to regulate complex IV assembly and respiration FASEB J. 25 2 2011 600 612
-
(2011)
FASEB J.
, vol.25
, Issue.2
, pp. 600-612
-
-
Strub, G.M.1
-
56
-
-
84904130220
-
Sphingosine 1-phosphate (S1P) promotes mitochondrial biogenesis in Hep G2 cells by activating peroxisome proliferator-activated receptor gamma coactivator 1alpha (PGC-1alpha)
-
Z. Shen, and et al. Sphingosine 1-phosphate (S1P) promotes mitochondrial biogenesis in Hep G2 cells by activating peroxisome proliferator-activated receptor gamma coactivator 1alpha (PGC-1alpha) Cell Stress Chaperones 19 4 2014 541 548
-
(2014)
Cell Stress Chaperones
, vol.19
, Issue.4
, pp. 541-548
-
-
Shen, Z.1
-
57
-
-
74449090932
-
Involvement of mitochondria on neuroprotective effect of sphingosine-1-phosphate in cell death in an in vitro model of brain ischemia
-
A. Agudo-Lopez, and et al. Involvement of mitochondria on neuroprotective effect of sphingosine-1-phosphate in cell death in an in vitro model of brain ischemia Neurosci. Lett. 470 2 2010 130 133
-
(2010)
Neurosci. Lett.
, vol.470
, Issue.2
, pp. 130-133
-
-
Agudo-Lopez, A.1
-
58
-
-
0035525748
-
Sphingosine 1-phosphate antagonizes apoptosis of human leukemia cells by inhibiting release of cytochrome c and Smac/DIABLO from mitochondria
-
O. Cuvillier, and T. Levade Sphingosine 1-phosphate antagonizes apoptosis of human leukemia cells by inhibiting release of cytochrome c and Smac/DIABLO from mitochondria Blood 98 9 2001 2828 2836
-
(2001)
Blood
, vol.98
, Issue.9
, pp. 2828-2836
-
-
Cuvillier, O.1
Levade, T.2
-
59
-
-
84879165160
-
Oxidative stress: The mitochondria-dependent and mitochondria-independent pathways of apoptosis
-
K. Sinha, and et al. Oxidative stress: the mitochondria-dependent and mitochondria-independent pathways of apoptosis Arch. Toxicol. 87 7 2013 1157 1180
-
(2013)
Arch. Toxicol.
, vol.87
, Issue.7
, pp. 1157-1180
-
-
Sinha, K.1
-
60
-
-
81255159138
-
Neutral sphingomyelinase activation precedes NADPH oxidase-dependent damage in neurons exposed to the proinflammatory cytokine tumor necrosis factor-alpha
-
B.M. Barth, S.J. Gustafson, and T.B. Kuhn Neutral sphingomyelinase activation precedes NADPH oxidase-dependent damage in neurons exposed to the proinflammatory cytokine tumor necrosis factor-alpha J. Neurosci. Res. 90 1 2012 229 242
-
(2012)
J. Neurosci. Res.
, vol.90
, Issue.1
, pp. 229-242
-
-
Barth, B.M.1
Gustafson, S.J.2
Kuhn, T.B.3
-
61
-
-
0033973670
-
Rapid activation of neutral sphingomyelinase by hypoxia-reoxygenation of cardiac myocytes
-
O.M. Hernandez, and et al. Rapid activation of neutral sphingomyelinase by hypoxia-reoxygenation of cardiac myocytes Circ. Res. 86 2 2000 198 204
-
(2000)
Circ. Res.
, vol.86
, Issue.2
, pp. 198-204
-
-
Hernandez, O.M.1
-
62
-
-
33846078397
-
Shooting the messenger: Oxidative stress regulates sphingosine-1-phosphate
-
M. Maceyka, S. Milstien, and S. Spiegel Shooting the messenger: oxidative stress regulates sphingosine-1-phosphate Circ. Res. 100 1 2007 7 9
-
(2007)
Circ. Res.
, vol.100
, Issue.1
, pp. 7-9
-
-
Maceyka, M.1
Milstien, S.2
Spiegel, S.3
-
63
-
-
33846047834
-
Oxidative stress-dependent sphingosine kinase-1 inhibition mediates monoamine oxidase A-associated cardiac cell apoptosis
-
D. Pchejetski, and et al. Oxidative stress-dependent sphingosine kinase-1 inhibition mediates monoamine oxidase A-associated cardiac cell apoptosis Circ. Res 100 1 2007 41 49
-
(2007)
Circ. Res
, vol.100
, Issue.1
, pp. 41-49
-
-
Pchejetski, D.1
-
64
-
-
84863009089
-
The control of the balance between ceramide and sphingosine-1-phosphate by sphingosine kinase: Oxidative stress and the seesaw of cell survival and death
-
J.R. Van Brocklyn, and J.B. Williams The control of the balance between ceramide and sphingosine-1-phosphate by sphingosine kinase: oxidative stress and the seesaw of cell survival and death Comp. Biochem. Physiol. B Biochem. Mol. Biol. 163 1 2012 26 36
-
(2012)
Comp. Biochem. Physiol. B Biochem. Mol. Biol.
, vol.163
, Issue.1
, pp. 26-36
-
-
Van Brocklyn, J.R.1
Williams, J.B.2
-
65
-
-
84911007634
-
Sphingosine kinase 1 and sphingosine-1-phosphate in oxidative stress evoked by 1-methyl-4-phenylpyridinium (MPP+) in human dopaminergic neuronal cells
-
J. Pyszko, and J.B. Strosznajder Sphingosine kinase 1 and sphingosine-1-phosphate in oxidative stress evoked by 1-methyl-4-phenylpyridinium (MPP+) in human dopaminergic neuronal cells Mol. Neurobiol. 50 1 2014 38 48
-
(2014)
Mol. Neurobiol.
, vol.50
, Issue.1
, pp. 38-48
-
-
Pyszko, J.1
Strosznajder, J.B.2
-
66
-
-
84867576045
-
Phytosphingosine-1-phosphate represses the hydrogen peroxide-induced activation of c-Jun N-terminal kinase in human dermal fibroblasts through the phosphatidylinositol 3-kinase/Akt pathway
-
J.P. Lee, and et al. Phytosphingosine-1-phosphate represses the hydrogen peroxide-induced activation of c-Jun N-terminal kinase in human dermal fibroblasts through the phosphatidylinositol 3-kinase/Akt pathway Arch. Dermatol. Res 304 8 2012 673 678
-
(2012)
Arch. Dermatol. Res
, vol.304
, Issue.8
, pp. 673-678
-
-
Lee, J.P.1
-
67
-
-
84895540233
-
Exogenous sphingosine 1- phosphate protects murine splenocytes against hypoxia-induced injury
-
S. Chawla, and et al. Exogenous sphingosine 1- phosphate protects murine splenocytes against hypoxia-induced injury Lipids 49 2 2014 191 202
-
(2014)
Lipids
, vol.49
, Issue.2
, pp. 191-202
-
-
Chawla, S.1
-
68
-
-
33745253950
-
Soluble oligomers of amyloid- beta peptide induce neuronal apoptosis by activating a cPLA2-dependent sphingomyelinase- ceramide pathway
-
C. Malaplate-Armand, and et al. Soluble oligomers of amyloid- beta peptide induce neuronal apoptosis by activating a cPLA2-dependent sphingomyelinase- ceramide pathway Neurobiol. Dis. 23 1 2006 178 189
-
(2006)
Neurobiol. Dis.
, vol.23
, Issue.1
, pp. 178-189
-
-
Malaplate-Armand, C.1
-
69
-
-
34547182992
-
Critical role for sphingosine kinase-1 in regulating survival of neuroblastoma cells exposed to amyloid-beta peptide
-
A. Gomez-Brouchet, and et al. Critical role for sphingosine kinase-1 in regulating survival of neuroblastoma cells exposed to amyloid-beta peptide Mol. Pharmacol. 72 2 2007 341 349
-
(2007)
Mol. Pharmacol.
, vol.72
, Issue.2
, pp. 341-349
-
-
Gomez-Brouchet, A.1
-
70
-
-
66449084111
-
Subcellular origin of sphingosine 1-phosphate is essential for its toxic effect in lyase-deficient neurons
-
N. Hagen, and et al. Subcellular origin of sphingosine 1-phosphate is essential for its toxic effect in lyase-deficient neurons J. Biol. Chem. 284 17 2009 11346 11353
-
(2009)
J. Biol. Chem.
, vol.284
, Issue.17
, pp. 11346-11353
-
-
Hagen, N.1
-
71
-
-
79551674537
-
FTY720 (fingolimod) efficacy in an animal model of multiple sclerosis requires astrocyte sphingosine 1-phosphate receptor 1 (S1P1) modulation
-
J.W. Choi, and et al. FTY720 (fingolimod) efficacy in an animal model of multiple sclerosis requires astrocyte sphingosine 1-phosphate receptor 1 (S1P1) modulation Proc. Natl. Acad. Sci. U. S. A. 108 2 2011 751 756
-
(2011)
Proc. Natl. Acad. Sci. U. S. A.
, vol.108
, Issue.2
, pp. 751-756
-
-
Choi, J.W.1
-
72
-
-
84875028261
-
Dual effects of daily FTY720 on human astrocytes in vitro: Relevance for neuroinflammation
-
C. Wu, and et al. Dual effects of daily FTY720 on human astrocytes in vitro: relevance for neuroinflammation J. Neuroinflammation 10 2013 41
-
(2013)
J. Neuroinflammation
, vol.10
, pp. 41
-
-
Wu, C.1
-
73
-
-
77953225859
-
Fingolimod (FTY720) enhances remyelination following demyelination of organotypic cerebellar slices
-
V.E. Miron, and et al. Fingolimod (FTY720) enhances remyelination following demyelination of organotypic cerebellar slices Am. J. Pathol. 176 6 2010 2682 2694
-
(2010)
Am. J. Pathol.
, vol.176
, Issue.6
, pp. 2682-2694
-
-
Miron, V.E.1
-
74
-
-
84875367110
-
Fingolimod phosphate promotes the neuroprotective effects of microglia
-
H. Noda, and et al. Fingolimod phosphate promotes the neuroprotective effects of microglia J. Neuroimmunol. 256 1-2 2013 13 18
-
(2013)
J. Neuroimmunol.
, vol.256
, Issue.1-2
, pp. 13-18
-
-
Noda, H.1
-
75
-
-
84876095698
-
Fingolimod phosphate attenuates oligomeric amyloid beta-induced neurotoxicity via increased brain-derived neurotrophic factor expression in neurons
-
Y. Doi, and et al. Fingolimod phosphate attenuates oligomeric amyloid beta-induced neurotoxicity via increased brain-derived neurotrophic factor expression in neurons PLoS One 8 4 2013 e61988
-
(2013)
PLoS One
, vol.8
, Issue.4
-
-
Doi, Y.1
-
76
-
-
84898987283
-
Fingolimod increases brain- derived neurotrophic factor levels and ameliorates amyloid beta-induced memory impairment
-
K. Fukumoto, and et al. Fingolimod increases brain- derived neurotrophic factor levels and ameliorates amyloid beta-induced memory impairment Behav. Brain Res. 268 2014 88 93
-
(2014)
Behav. Brain Res.
, vol.268
, pp. 88-93
-
-
Fukumoto, K.1
-
77
-
-
84865538160
-
Fingolimod, a sphingosine-1 phosphate receptor modulator, increases BDNF levels and improves symptoms of a mouse model of Rett syndrome
-
R. Deogracias, and et al. Fingolimod, a sphingosine-1 phosphate receptor modulator, increases BDNF levels and improves symptoms of a mouse model of Rett syndrome Proc. Natl Acad Sci U. S. A. 109 35 2012 14230 14235
-
(2012)
Proc. Natl Acad Sci U. S. A.
, vol.109
, Issue.35
, pp. 14230-14235
-
-
Deogracias, R.1
-
78
-
-
77449106966
-
Activation of sphingosine 1-phosphate receptor-1 by FTY720 is neuroprotective after ischemic stroke in rats
-
Y. Hasegawa, and et al. Activation of sphingosine 1-phosphate receptor-1 by FTY720 is neuroprotective after ischemic stroke in rats Stroke 41 2 2010 368 374
-
(2010)
Stroke
, vol.41
, Issue.2
, pp. 368-374
-
-
Hasegawa, Y.1
-
79
-
-
79551495392
-
Fingolimod provides long-term protection in rodent models of cerebral ischemia
-
Y. Wei, and et al. Fingolimod provides long-term protection in rodent models of cerebral ischemia Ann. Neurol. 69 1 2011 119 129
-
(2011)
Ann. Neurol.
, vol.69
, Issue.1
, pp. 119-129
-
-
Wei, Y.1
-
80
-
-
84878950876
-
FTY720 (fingolimod) attenuates beta-amyloid peptide (Abeta42)-induced impairment of spatial learning and memory in rats
-
M. Asle-Rousta, and et al. FTY720 (fingolimod) attenuates beta-amyloid peptide (Abeta42)-induced impairment of spatial learning and memory in rats J. Mol. Neurosci. 50 3 2013 524 532
-
(2013)
J. Mol. Neurosci.
, vol.50
, Issue.3
, pp. 524-532
-
-
Asle-Rousta, M.1
-
81
-
-
84936754866
-
Crosstalk between insulin and toll-like receptor signaling pathways in the central nervous system
-
F. Hemmati, and et al. Crosstalk between insulin and toll-like receptor signaling pathways in the central nervous system Mol. Neurobiol. 50 3 2014 797 810
-
(2014)
Mol. Neurobiol.
, vol.50
, Issue.3
, pp. 797-810
-
-
Hemmati, F.1
-
82
-
-
84867277240
-
Toll-like receptors, signaling adapters and regulation of the pro-inflammatory response by PI3K
-
T.D. Troutman, J.F. Bazan, and C. Pasare Toll-like receptors, signaling adapters and regulation of the pro-inflammatory response by PI3K Cell Cycle 11 19 2012 3559 3567
-
(2012)
Cell Cycle
, vol.11
, Issue.19
, pp. 3559-3567
-
-
Troutman, T.D.1
Bazan, J.F.2
Pasare, C.3
-
83
-
-
84867013405
-
2-induced granulosa cell apoptosis via the PI3K/Akt signaling pathway
-
2-induced granulosa cell apoptosis via the PI3K/Akt signaling pathway Fertil. Steril. 98 4 2012 1001 1008.e1
-
(2012)
Fertil. Steril.
, vol.98
, Issue.4
, pp. 1001e1-1008e1
-
-
Nakahara, T.1
-
84
-
-
84939946943
-
Activation of S1P(1) receptor regulates PI3K/Akt/FoxO3a pathway in response to oxidative stress in PC12 cells
-
F. Safarian, and et al. Activation of S1P(1) receptor regulates PI3K/Akt/FoxO3a pathway in response to oxidative stress in PC12 cells J. Mol. Neurosci. 56 1 2015 177 187
-
(2015)
J. Mol. Neurosci.
, vol.56
, Issue.1
, pp. 177-187
-
-
Safarian, F.1
-
85
-
-
84878133071
-
Sphingosine-1-phosphate promotes the nuclear translocation of beta-catenin and thereby induces osteoprotegerin gene expression in osteoblast-like cell lines
-
E. Matsuzaki, and et al. Sphingosine-1-phosphate promotes the nuclear translocation of beta-catenin and thereby induces osteoprotegerin gene expression in osteoblast-like cell lines Bone 55 2 2013 315 324
-
(2013)
Bone
, vol.55
, Issue.2
, pp. 315-324
-
-
Matsuzaki, E.1
-
86
-
-
0035936023
-
The protein kinase PKB/Akt regulates cell survival and apoptosis by inhibiting Bax conformational change
-
H. Yamaguchi, and H.G. Wang The protein kinase PKB/Akt regulates cell survival and apoptosis by inhibiting Bax conformational change Oncogene 20 53 2001 7779 7786
-
(2001)
Oncogene
, vol.20
, Issue.53
, pp. 7779-7786
-
-
Yamaguchi, H.1
Wang, H.G.2
-
87
-
-
84862294189
-
ERK1/2 MAP kinases: Structure, function, and regulation
-
R. Roskoski Jr. ERK1/2 MAP kinases: structure, function, and regulation Pharmacol. Res. 66 2 2012 105 143
-
(2012)
Pharmacol. Res.
, vol.66
, Issue.2
, pp. 105-143
-
-
Roskoski, R.1
-
88
-
-
73649091056
-
ERK and cell death: ERK1/2 in neuronal death
-
S. Subramaniam, and K. Unsicker ERK and cell death: ERK1/2 in neuronal death FEBS J. 277 1 2001 22 29
-
(2001)
FEBS J.
, vol.277
, Issue.1
, pp. 22-29
-
-
Subramaniam, S.1
Unsicker, K.2
-
89
-
-
37549049697
-
Anti-apoptotic effect of sphingosine-1-phosphate and platelet-derived growth factor in human embryonic stem cells
-
R.C. Wong, and et al. Anti-apoptotic effect of sphingosine-1-phosphate and platelet-derived growth factor in human embryonic stem cells Stem Cells Dev. 16 6 2007 989 1002
-
(2007)
Stem Cells Dev.
, vol.16
, Issue.6
, pp. 989-1002
-
-
Wong, R.C.1
-
90
-
-
33751190327
-
A death-promoting role for extracellular signal- regulated kinase
-
S. Zhuang, and R.G. Schnellmann A death-promoting role for extracellular signal- regulated kinase J. Pharmacol. Exp. Ther. 319 3 2006 991 997
-
(2006)
J. Pharmacol. Exp. Ther.
, vol.319
, Issue.3
, pp. 991-997
-
-
Zhuang, S.1
Schnellmann, R.G.2
-
91
-
-
15244352198
-
Emerging role for ERK as a key regulator of neuronal apoptosis
-
E.C. Cheung, and R.S. Slack Emerging role for ERK as a key regulator of neuronal apoptosis Sci. STKE 2004 251 2004 PE45
-
(2004)
Sci. STKE
, vol.2004
, Issue.251
, pp. PE45
-
-
Cheung, E.C.1
Slack, R.S.2
-
92
-
-
42749092078
-
Sphingosine 1-phosphate induces Mcl-1 upregulation and protects multiple myeloma cells against apoptosis
-
Q.F. Li, and et al. Sphingosine 1-phosphate induces Mcl-1 upregulation and protects multiple myeloma cells against apoptosis Biochem. Biophys. Res. Commun. 371 1 2008 159 162
-
(2008)
Biochem. Biophys. Res. Commun.
, vol.371
, Issue.1
, pp. 159-162
-
-
Li, Q.F.1
-
93
-
-
0242384063
-
Sphingosine-1-phosphate inhibits human keratinocyte proliferation via Akt/protein kinase B inactivation
-
D.S. Kim, and et al. Sphingosine-1-phosphate inhibits human keratinocyte proliferation via Akt/protein kinase B inactivation Cell Signal. 16 1 2004 89 95
-
(2004)
Cell Signal.
, vol.16
, Issue.1
, pp. 89-95
-
-
Kim, D.S.1
-
94
-
-
84911006921
-
Ceramide in the molecular mechanisms of neuronal cell death. the role of sphingosine-1-phosphate
-
K. Czubowicz, and R. Strosznajder Ceramide in the molecular mechanisms of neuronal cell death. The role of sphingosine-1-phosphate Mol. Neurobiol. 50 1 2014 26 37
-
(2014)
Mol. Neurobiol.
, vol.50
, Issue.1
, pp. 26-37
-
-
Czubowicz, K.1
Strosznajder, R.2
-
95
-
-
84889602370
-
Regulation of cell survival by sphingosine-1-phosphate receptor S1P1 via reciprocal ERK-dependent suppression of Bim and PI-3-kinase/protein kinase C-mediated upregulation of Mcl-1
-
C. Rutherford, and et al. Regulation of cell survival by sphingosine-1-phosphate receptor S1P1 via reciprocal ERK-dependent suppression of Bim and PI-3-kinase/protein kinase C-mediated upregulation of Mcl-1 Cell Death Dis. 4 2013 e927
-
(2013)
Cell Death Dis.
, vol.4
, pp. e927
-
-
Rutherford, C.1
-
96
-
-
30544434809
-
Regulation by sphingosine 1-phosphate of bax and bad activities during apoptosis in a MEK-dependent manner
-
S. Betito, and O. Cuvillier Regulation by sphingosine 1-phosphate of bax and bad activities during apoptosis in a MEK-dependent manner Biochem. Biophys. Res. Commun. 340 4 2006 1273 1277
-
(2006)
Biochem. Biophys. Res. Commun.
, vol.340
, Issue.4
, pp. 1273-1277
-
-
Betito, S.1
Cuvillier, O.2
-
97
-
-
0037468614
-
Sphingosine-1-phosphate inhibits acid sphingomyelinase and blocks apoptosis in macrophages
-
A. Gomez-Munoz, and et al. Sphingosine-1-phosphate inhibits acid sphingomyelinase and blocks apoptosis in macrophages FEBS Lett. 539 1-3 2003 56 60
-
(2003)
FEBS Lett.
, vol.539
, Issue.1-3
, pp. 56-60
-
-
Gomez-Munoz, A.1
-
98
-
-
85018196942
-
Sphingosin-1-phosphate receptor 1: A potential target to inhibit neuroinflammation and restore the Sphingosin-1-phosphate metabolism
-
Z. Kolahdooz, and et al. Sphingosin-1-phosphate receptor 1: a potential target to inhibit neuroinflammation and restore the Sphingosin-1-phosphate metabolism Can. J. Neurol. Sci. 42 2015 195 202
-
(2015)
Can. J. Neurol. Sci.
, vol.42
, pp. 195-202
-
-
Kolahdooz, Z.1
-
99
-
-
34848867249
-
Protein kinase D-mediated phosphorylation and nuclear export of sphingosine kinase 2
-
G. Ding, and et al. Protein kinase D-mediated phosphorylation and nuclear export of sphingosine kinase 2 J. Biol. Chem. 282 37 2007 27493 27502
-
(2007)
J. Biol. Chem.
, vol.282
, Issue.37
, pp. 27493-27502
-
-
Ding, G.1
-
100
-
-
69949113620
-
Regulation of histone acetylation in the nucleus by sphingosine-1-phosphate
-
N.C. Hait, and et al. Regulation of histone acetylation in the nucleus by sphingosine-1-phosphate Science 325 5945 2009 1254 1257
-
(2009)
Science
, vol.325
, Issue.5945
, pp. 1254-1257
-
-
Hait, N.C.1
-
101
-
-
77953923379
-
Sphingosine-1-phosphate is a missing cofactor for the E3 ubiquitin ligase TRAF2
-
S.E. Alvarez, and et al. Sphingosine-1-phosphate is a missing cofactor for the E3 ubiquitin ligase TRAF2 Nature 465 7301 2010 1084 1088
-
(2010)
Nature
, vol.465
, Issue.7301
, pp. 1084-1088
-
-
Alvarez, S.E.1
-
102
-
-
74149083982
-
Deregulation of sphingolipid metabolism in Alzheimer's disease
-
X. He, and et al. Deregulation of sphingolipid metabolism in Alzheimer's disease Neurobiol. Aging 31 3 2010 398 408
-
(2010)
Neurobiol. Aging
, vol.31
, Issue.3
, pp. 398-408
-
-
He, X.1
-
103
-
-
10944272619
-
Fibrillar amyloid-beta peptides kill human primary neurons via NADPH oxidase-mediated activation of neutral sphingomyelinase. Implications for Alzheimer's disease
-
A. Jana, and K. Pahan Fibrillar amyloid-beta peptides kill human primary neurons via NADPH oxidase-mediated activation of neutral sphingomyelinase. Implications for Alzheimer's disease J. Biol. Chem. 279 49 2004 51451 51459
-
(2004)
J. Biol. Chem.
, vol.279
, Issue.49
, pp. 51451-51459
-
-
Jana, A.1
Pahan, K.2
-
104
-
-
0347122965
-
Amyloid-beta peptide induces oligodendrocyte death by activating the neutral sphingomyelinase-ceramide pathway
-
J.T. Lee, and et al. Amyloid-beta peptide induces oligodendrocyte death by activating the neutral sphingomyelinase-ceramide pathway J. Cell Biol. 164 1 2004 123 131
-
(2004)
J. Cell Biol.
, vol.164
, Issue.1
, pp. 123-131
-
-
Lee, J.T.1
-
105
-
-
84905406924
-
Sphingosine kinase-1 protects differentiated n2a cells against Beta-amyloid25-35-induced neurotoxicity via the mitochondrial pathway
-
Y. Yang, and et al. Sphingosine kinase-1 protects differentiated n2a cells against Beta-amyloid25-35-induced neurotoxicity via the mitochondrial pathway Neurochem. Res. 39 5 2014 932 940
-
(2014)
Neurochem. Res.
, vol.39
, Issue.5
, pp. 932-940
-
-
Yang, Y.1
-
106
-
-
84902831529
-
Reduced sphingosine kinase-1 and enhanced sphingosine 1-phosphate lyase expression demonstrate deregulated sphingosine 1-phosphate signaling in Alzheimer's disease
-
J. Ceccom, and et al. Reduced sphingosine kinase-1 and enhanced sphingosine 1-phosphate lyase expression demonstrate deregulated sphingosine 1-phosphate signaling in Alzheimer's disease Acta Neuropathol. Commun. 2 1 2014 12
-
(2014)
Acta Neuropathol. Commun.
, vol.2
, Issue.1
, pp. 12
-
-
Ceccom, J.1
-
107
-
-
79955770841
-
BACE1 activity is modulated by cell-associated sphingosine-1-phosphate
-
N. Takasugi, and et al. BACE1 activity is modulated by cell-associated sphingosine-1-phosphate J. Neurosci. 31 18 2011 6850 6857
-
(2011)
J. Neurosci.
, vol.31
, Issue.18
, pp. 6850-6857
-
-
Takasugi, N.1
-
108
-
-
55749104704
-
A defect of sphingolipid metabolism modifies the properties of normal appearing white matter in multiple sclerosis
-
D. Wheeler, and et al. A defect of sphingolipid metabolism modifies the properties of normal appearing white matter in multiple sclerosis Brain 131 2008 3092 3102
-
(2008)
Brain
, vol.131
, pp. 3092-3102
-
-
Wheeler, D.1
-
109
-
-
77951991002
-
Neurons and oligodendrocytes recycle sphingosine 1-phosphate to ceramide: Significance for apoptosis and multiple sclerosis
-
J. Qin, and et al. Neurons and oligodendrocytes recycle sphingosine 1-phosphate to ceramide: significance for apoptosis and multiple sclerosis J. Biol. Chem. 285 19 2010 14134 14143
-
(2010)
J. Biol. Chem.
, vol.285
, Issue.19
, pp. 14134-14143
-
-
Qin, J.1
-
110
-
-
77956568581
-
Sphingosine 1-phosphate receptor 1 and 3 are upregulated in multiple sclerosis lesions
-
R. Van Doorn, and et al. Sphingosine 1-phosphate receptor 1 and 3 are upregulated in multiple sclerosis lesions Glia 58 12 2010 1465 1476
-
(2010)
Glia
, vol.58
, Issue.12
, pp. 1465-1476
-
-
Van Doorn, R.1
-
111
-
-
36549047503
-
Brain sphingosine-1-phosphate receptors: Implication for FTY720 in the treatment of multiple sclerosis
-
K.K. Dev, and et al. Brain sphingosine-1-phosphate receptors: implication for FTY720 in the treatment of multiple sclerosis Pharmacol. Ther. 117 1 2008 77 93
-
(2008)
Pharmacol. Ther.
, vol.117
, Issue.1
, pp. 77-93
-
-
Dev, K.K.1
-
112
-
-
84876119766
-
Fingolimod: Direct CNS effects of sphingosine 1 -phosphate (S1P) receptor modulation and implications in multiple sclerosis therapy
-
A. Groves, Y. Kihara, and J. Chun Fingolimod: direct CNS effects of sphingosine 1 -phosphate (S1P) receptor modulation and implications in multiple sclerosis therapy J. Neurol. Sci. 328 1-2 2013 9 18
-
(2013)
J. Neurol. Sci.
, vol.328
, Issue.1-2
, pp. 9-18
-
-
Groves, A.1
Kihara, Y.2
Chun, J.3
-
113
-
-
84897541254
-
FTY720 (fingolimod) is a neuroprotective and disease-modifying agent in cellular and mouse models of Huntington disease
-
A. Di Pardo, and et al. FTY720 (fingolimod) is a neuroprotective and disease-modifying agent in cellular and mouse models of Huntington disease Hum. Mol. Genet. 23 9 2014 2251 2265
-
(2014)
Hum. Mol. Genet.
, vol.23
, Issue.9
, pp. 2251-2265
-
-
Di Pardo, A.1
-
114
-
-
84891416141
-
A Metabolic Shift Favoring Sphingosine 1-Phosphate at the Expense of Ceramide Controls Glioblastoma Angiogenesis
-
H.J. Abuhusain, and et al. A Metabolic Shift Favoring Sphingosine 1-Phosphate at the Expense of Ceramide Controls Glioblastoma Angiogenesis J. Biol. Chem. 288 52 2013 37355 37364
-
(2013)
J. Biol. Chem.
, vol.288
, Issue.52
, pp. 37355-37364
-
-
Abuhusain, H.J.1
-
115
-
-
84879472607
-
Extracellular sphingosine-1-phosphate: A novel actor in human glioblastoma stem cell survival
-
E. Riccitelli, and et al. Extracellular sphingosine-1-phosphate: a novel actor in human glioblastoma stem cell survival PLoS One 8 6 2013 e68229
-
(2013)
PLoS One
, vol.8
, Issue.6
-
-
Riccitelli, E.1
|