-
1
-
-
0036319335
-
Astrocyte-endothelial interactions and blood-brain barrier permeability
-
Abbott N. 2002. Astrocyte-endothelial interactions and blood-brain barrier permeability. J Anat 200:527.
-
(2002)
J Anat
, vol.200
, pp. 527
-
-
Abbott, N.1
-
2
-
-
3242671309
-
Cell surface receptors in lysophospholipid signaling
-
Anliker B, Chun J. 2004. Cell surface receptors in lysophospholipid signaling. Semin Cell Dev Biol 15:457-465.
-
(2004)
Semin Cell Dev Biol
, vol.15
, pp. 457-465
-
-
Anliker, B.1
Chun, J.2
-
3
-
-
0037077308
-
The immune modulator FTY720 targets sphingosine 1-phosphate receptors
-
Brinkmann V, Davis MD, Heise CE, Albert R, Cottens S, Hof R, Bruns C, Prieschl E, Baumruker T, Hiestand P, Foster CA, Zollinger M, Lynch KR. 2002. The immune modulator FTY720 targets sphingosine 1-phosphate receptors. J Biol Chem 277:21453-21457.
-
(2002)
J Biol Chem
, vol.277
, pp. 21453-21457
-
-
Brinkmann, V.1
Davis, M.D.2
Heise, C.E.3
Albert, R.4
Cottens, S.5
Hof, R.6
Bruns, C.7
Prieschl, E.8
Baumruker, T.9
Hiestand, P.10
Foster, C.A.11
Zollinger, M.12
Lynch, K.R.13
-
4
-
-
27844517355
-
Sphingosine 1-phosphate and ceramide 1-phosphate: Expanding roles in cell signaling
-
Chalfant CE, Spiegel S. 2005. Sphingosine 1-phosphate and ceramide 1-phosphate: Expanding roles in cell signaling. J Cell Sci 118:4605-4612.
-
(2005)
J Cell Sci
, vol.118
, pp. 4605-4612
-
-
Chalfant, C.E.1
Spiegel, S.2
-
5
-
-
0030841387
-
Establishment of human adult astrocyte cultures derived from postmortem multiple sclerosis and control brain and spinal cord regions: Immunophenotypical and functional characterization
-
DOI 10.1002/(SICI)1097-4547(19970801)49:3<342::AID-JNR9>3.0.CO;2-C
-
De Groot CJ, Langeveld CH, Jongenelen CA, Montagne L, van der Valk P, Dijkstra CD. 1997. Establishment of human adult astrocyte cultures derived from postmortem multiple sclerosis and control brain and spinal cord regions: Immunophenotypical and functional characterization. J Neurosci Res 49:342-354. (Pubitemid 27344194)
-
(1997)
Journal of Neuroscience Research
, vol.49
, Issue.3
, pp. 342-354
-
-
De Groot, C.J.A.1
Langeveld, C.H.2
Jongenelen, C.A.M.3
Montagne, L.4
Van Der Valk, P.5
Dijkstra, C.D.6
-
6
-
-
0033180342
-
The glial scar and central nervous system repair
-
Fawcett JW, Asher RA. 1999. The glial scar and central nervous system repair. Brain Res Bull 49:377-391.
-
(1999)
Brain Res Bull
, vol.49
, pp. 377-391
-
-
Fawcett, J.W.1
Asher, R.A.2
-
7
-
-
35348970884
-
Brain penetration of the oral immunomodulatory drug FTY720 and its phosphorylation in the central nervous system during experimental autoimmune encephalomyelitis: Consequences for mode of action in multiple sclerosis
-
Foster CA, Howard LM, Schweitzer A, Persohn E, Hiestand PC, Balatoni B, Reuschel R, Beerli C, Schwartz M, Billich A. 2007. Brain penetration of the oral immunomodulatory drug FTY720 and its phosphorylation in the central nervous system during experimental autoimmune encephalomyelitis: Consequences for mode of action in multiple sclerosis. J Pharmacol Exp Ther 323:469-475.
-
(2007)
J Pharmacol Exp Ther
, vol.323
, pp. 469-475
-
-
Foster, C.A.1
Howard, L.M.2
Schweitzer, A.3
Persohn, E.4
Hiestand, P.C.5
Balatoni, B.6
Reuschel, R.7
Beerli, C.8
Schwartz, M.9
Billich, A.10
-
8
-
-
2442679391
-
The immunosuppressant FTY720 downregulates sphingosine 1-phosphate G-protein-coupled receptors
-
Graler MH, Goetzl EJ. 2004. The immunosuppressant FTY720 downregulates sphingosine 1-phosphate G-protein-coupled receptors. FASEB J 18:551-553.
-
(2004)
FASEB J
, vol.18
, pp. 551-553
-
-
Graler, M.H.1
Goetzl, E.J.2
-
9
-
-
33947634013
-
Erythrocytes store and release sphingosine 1-phosphate in blood
-
DOI 10.1096/fj.06-7433com
-
Hanel P, Andreani P, Graler MH. 2007. Erythrocytes store and release sphingosine 1-phosphate in blood. FASEB J 21:1202-1209. (Pubitemid 46495709)
-
(2007)
FASEB Journal
, vol.21
, Issue.4
, pp. 1202-1209
-
-
Hanel, P.1
Andreani, P.2
Graler, M.H.3
-
10
-
-
0029166259
-
Production and function of monocyte chemoattractant protein-1 and other β-chemokines in murine glial cells
-
Hayashi M, Luo Y, Laning J, Strieter RM, Dorf ME. 1995. Production and function of monocyte chemoattractant protein-1 and other β-chemokines in murine glial cells. J Neuroimmunol 60:143-150.
-
(1995)
J Neuroimmunol
, vol.60
, pp. 143-150
-
-
Hayashi, M.1
Luo, Y.2
Laning, J.3
Strieter, R.M.4
Dorf, M.E.5
-
11
-
-
17044411325
-
Analysis of endogenous S1P and LPA receptor expression in CHO-K1 cells
-
Holdsworth G, Slocombe P, Hutchinson G, Milligan G. 2005. Analysis of endogenous S1P and LPA receptor expression in CHO-K1 cells. Gene 350:59-63.
-
(2005)
Gene
, vol.350
, pp. 59-63
-
-
Holdsworth, G.1
Slocombe, P.2
Hutchinson, G.3
Milligan, G.4
-
12
-
-
0034596949
-
Resistance to experimental autoimmune encephalomyelitis in mice lacking the CC chemokine receptor (CCR)2
-
Izikson L, Klein RS, Charo IF, Weiner HL, Luster AD. 2000. Resistance to experimental autoimmune encephalomyelitis in mice lacking the CC chemokine receptor (CCR)2. J Exp Med 192:1075-1080.
-
(2000)
J Exp Med
, vol.192
, pp. 1075-1080
-
-
Izikson, L.1
Klein, R.S.2
Charo, I.F.3
Weiner, H.L.4
Luster, A.D.5
-
13
-
-
34250648475
-
Validation of a rapid, non-radioactive method to quantify internalisation of G-protein coupled receptors
-
DOI 10.1007/s00210-007-0164-8
-
Jongsma M, Florczyk UM, Hendriks-Balk MC, Michel MC, Peters SL, Alewijnse AE. 2007. Validation of a rapid, non-radioactive method to quantify internalisation of G-protein coupled receptors. Naunyn Schmiedebergs Arch Pharmacol 375:329-336. (Pubitemid 46945334)
-
(2007)
Naunyn-Schmiedeberg's Archives of Pharmacology
, vol.375
, Issue.5
, pp. 329-336
-
-
Jongsma, M.1
Florczyk, U.M.2
Hendriks-Balk, M.C.3
Michel, M.C.4
Peters, S.L.M.5
Alewijnse, A.E.6
-
14
-
-
33749018836
-
BML-241 fails to display selective antagonism at the sphingosine- 1-phosphate receptor, S1P(3)
-
Jongsma M, Hendriks-Balk MC, Michel MC, Peters SL, Alewijnse AE. 2006. BML-241 fails to display selective antagonism at the sphingosine- 1-phosphate receptor, S1P(3). Br J Pharmacol 149:277-282.
-
(2006)
Br J Pharmacol
, vol.149
, pp. 277-282
-
-
Jongsma, M.1
Hendriks-Balk, M.C.2
Michel, M.C.3
Peters, S.L.4
Alewijnse, A.E.5
-
15
-
-
77955799815
-
Oral fingolimod (FTY720) for relapsing multiple sclerosis
-
Kappos L, Antel J, Comi G, Montalban X, O'Connor P, Polman CH, Haas T, Korn AA, Karlsson G, Radue EW. 2006. Oral fingolimod (FTY720) for relapsing multiple sclerosis. N Engl J Med 355:1124-1140.
-
(2006)
N Engl J Med
, vol.355
, pp. 1124-1140
-
-
Kappos, L.1
Antel, J.2
Comi, G.3
Montalban, X.4
O'Connor, P.5
Polman, Ch.6
Haas, T.7
Korn, A.A.8
Karlsson, G.9
Radue, E.W.10
-
16
-
-
1642580757
-
Lymphocyte egress from thymus and peripheral lymphoid organs is dependent on S1P receptor 1
-
Matloubian M, Lo CG, Cinamon G, Lesneski MJ, Xu Y, Brinkmann V, Allende ML, Proia RL, Cyster JG. 2004. Lymphocyte egress from thymus and peripheral lymphoid organs is dependent on S1P receptor 1. Nature 427:355-360.
-
(2004)
Nature
, vol.427
, pp. 355-360
-
-
Matloubian, M.1
Lo, C.G.2
Cinamon, G.3
Lesneski, M.J.4
Xu, Y.5
Brinkmann, V.6
Allende, M.L.7
Proia, R.L.8
Cyster, J.G.9
-
17
-
-
54449099880
-
FTY720 therapy exerts differential effects on T cell subsets in multiple sclerosis
-
Mehling M, Brinkmann V, Antel J, Bar-Or A, Goebels N, Vedrine C, Kristofic C, Kuhle J, Lindberg RL, Kappos L. 2008. FTY720 therapy exerts differential effects on T cell subsets in multiple sclerosis. Neurology 71:1261-1267.
-
(2008)
Neurology
, vol.71
, pp. 1261-1267
-
-
Mehling, M.1
Brinkmann, V.2
Antel, J.3
Bar-Or, A.4
Goebels, N.5
Vedrine, C.6
Kristofic, C.7
Kuhle, J.8
Lindberg, R.L.9
Kappos, L.10
-
18
-
-
53149089045
-
Cyclical and dose-dependent responses of adult human mature oligodendrocytes to fingolimod
-
Miron VE, Hall JA, Kennedy TE, Soliven B, Antel JP. 2008a. Cyclical and dose-dependent responses of adult human mature oligodendrocytes to fingolimod. Am J Pathol 173:1143-1152.
-
(2008)
Am J Pathol
, vol.173
, pp. 1143-1152
-
-
Miron, V.E.1
Hall, J.A.2
Kennedy, T.E.3
Soliven, B.4
Antel, J.P.5
-
19
-
-
39049125218
-
FTY720 modulates human oligodendrocyte progenitor process extension and survival
-
DOI 10.1002/ana.21227
-
Miron VE, Jung CG, Kim HJ, Kennedy TE, Soliven B, Antel JP. 2008b. FTY720 modulates human oligodendrocyte progenitor process extension and survival. Ann Neurol 63:61-71. (Pubitemid 351240552)
-
(2008)
Annals of Neurology
, vol.63
, Issue.1
, pp. 61-71
-
-
Miron, V.E.1
Jung, C.G.2
Kim, H.J.3
Kennedy, T.E.4
Soliven, B.5
Antel, J.P.6
-
20
-
-
34547431060
-
Phosphorylated FTY720 promotes astrocyte migration through sphingosine-1-phosphate receptors
-
Mullershausen F, Craveiro LM, Shin Y, Cortes-Cros M, Bassilana F, Osinde M, Wishart WL, Guerini D, Thallmair M, Schwab ME, Sivasankaran R, Seuwen K, Dev KK. 2007. Phosphorylated FTY720 promotes astrocyte migration through sphingosine-1-phosphate receptors. J Neurochem 102:1151-1161.
-
(2007)
J Neurochem
, vol.102
, pp. 1151-1161
-
-
Mullershausen, F.1
Craveiro, L.M.2
Shin, Y.3
Cortes-Cros, M.4
Bassilana, F.5
Osinde, M.6
Wishart, W.L.7
Guerini, D.8
Thallmair, M.9
Schwab, M.E.10
Sivasankaran, R.11
Seuwen, K.12
Dev, K.K.13
-
21
-
-
65949105042
-
Persistent signaling induced by FTY720-phosphate is mediated by internalized S1P1 receptors
-
Mullershausen F, Zecri F, Cetin C, Billich A, Guerini D, Seuwen K. 2009. Persistent signaling induced by FTY720-phosphate is mediated by internalized S1P1 receptors. Nat Chem Biol 5:428-434.
-
(2009)
Nat Chem Biol
, vol.5
, pp. 428-434
-
-
Mullershausen, F.1
Zecri, F.2
Cetin, C.3
Billich, A.4
Guerini, D.5
Seuwen, K.6
-
22
-
-
0034672133
-
Interaction of sphingosine 1-phosphate with plasma components, including lipoproteins, regulates the lipid receptor-mediated actions
-
Murata N, Sato K, Kon J, Tomura H, Yanagita M, Kuwabara A, Ui M, Okajima F. 2000. Interaction of sphingosine 1-phosphate with plasma components, including lipoproteins, regulates the lipid receptor-mediated actions. Biochem J 352 (Pt 3):809-815.
-
(2000)
Biochem J
, vol.352
, Issue.PART 3
, pp. 809-815
-
-
Murata, N.1
Sato, K.2
Kon, J.3
Tomura, H.4
Yanagita, M.5
Kuwabara, A.6
Ui, M.7
Okajima, F.8
-
23
-
-
34247874512
-
Immunosuppressive and anti-angiogenic sphingosine 1-phosphate receptor-1 agonists induce ubiquitinylation and proteasomal degradation of the receptor
-
Oo ML, Thangada S, Wu MT, Liu CH, Macdonald TL, Lynch KR, Lin CY, Hla T. 2007. Immunosuppressive and anti-angiogenic sphingosine 1-phosphate receptor-1 agonists induce ubiquitinylation and proteasomal degradation of the receptor. J Biol Chem 282:9082-9089.
-
(2007)
J Biol Chem
, vol.282
, pp. 9082-9089
-
-
Oo, M.L.1
Thangada, S.2
Wu, M.T.3
Liu, C.H.4
Macdonald, T.L.5
Lynch, K.R.6
Lin, C.Y.7
Hla, T.8
-
24
-
-
34047253376
-
Phosphorylated FTY720 stimulates ERK phosphorylation in astrocytes via S1P receptors
-
Osinde M, Mullershausen F, Dev KK. 2007. Phosphorylated FTY720 stimulates ERK phosphorylation in astrocytes via S1P receptors. Neuropharmacology 52:1210-1218.
-
(2007)
Neuropharmacology
, vol.52
, pp. 1210-1218
-
-
Osinde, M.1
Mullershausen, F.2
Dev, K.K.3
-
25
-
-
34247379074
-
Promotion of lymphocyte egress into blood and lymph by distinct sources of sphingosine-1-phosphate
-
Pappu R, Schwab SR, Cornelissen I, Pereira JP, Regard JB, Xu Y, Camerer E, Zheng YW, Huang Y, Cyster JG, Coughlin SR. 2007. Promotion of lymphocyte egress into blood and lymph by distinct sources of sphingosine-1-phosphate. Science 316:295-298.
-
(2007)
Science
, vol.316
, pp. 295-298
-
-
Pappu, R.1
Schwab, S.R.2
Cornelissen, I.3
Pereira, J.P.4
Regard, J.B.5
Xu, Y.6
Camerer, E.7
Zheng, Y.W.8
Huang, Y.9
Cyster, J.G.10
Coughlin, S.R.11
-
26
-
-
0034661482
-
Sphingosine 1-phosphate signalling in mammalian cells
-
Pyne S, Pyne NJ. 2000. Sphingosine 1-phosphate signalling in mammalian cells. Biochem J 349:385-402.
-
(2000)
Biochem J
, vol.349
, pp. 385-402
-
-
Pyne, S.1
Pyne, N.J.2
-
27
-
-
0027530096
-
Astrocyte expression of mRNA encoding cytokines IP-10 and JE/MCP-1 in experimental autoimmune encephalomyelitis
-
Ransohoff RM, Hamilton TA, Tani M, Stoler MH, Shick HE, Major JA, Estes ML, Thomas DM, Tuohy VK. 1993. Astrocyte expression of mRNA encoding cytokines IP-10 and JE/MCP-1 in experimental autoimmune encephalomyelitis. FASEB J 7:592-600.
-
(1993)
FASEB J
, vol.7
, pp. 592-600
-
-
Ransohoff, R.M.1
Hamilton, T.A.2
Tani, M.3
Stoler, M.H.4
Shick, H.E.5
Major, J.A.6
Estes, M.L.7
Thomas, D.M.8
Tuohy, V.K.9
-
28
-
-
12544253058
-
Structural and functional characteristics of S1P receptors
-
Sanchez T, Hla T. 2004. Structural and functional characteristics of S1P receptors. J Cell Biochem 92:913-922.
-
(2004)
J Cell Biochem
, vol.92
, pp. 913-922
-
-
Sanchez, T.1
Hla, T.2
-
29
-
-
0032522207
-
Expression of monocyte chemoattractant protein-1 and other β-chemokines by resident glia and inflammatory cells in multiple sclerosis lesions
-
Simpson JE, Newcombe J, Cuzner ML, Woodroofe MN. 1998. Expression of monocyte chemoattractant protein-1 and other β-chemokines by resident glia and inflammatory cells in multiple sclerosis lesions. J Neuroimmunol 84:238-249.
-
(1998)
J Neuroimmunol
, vol.84
, pp. 238-249
-
-
Simpson, J.E.1
Newcombe, J.2
Cuzner, M.L.3
Woodroofe, M.N.4
-
30
-
-
0031204792
-
Lipopolysaccharide-induced IL-12 expression in the central nervous system and cultured astrocytes and microglia
-
Stalder AK, Pagenstecher A, Yu NC, Kincaid C, Chiang CS, Hobbs MV, Bloom FE, Campbell IL. 1997. Lipopolysaccharide-induced IL-12 expression in the central nervous system and cultured astrocytes and microglia. J Immunol 159:1344-1351.
-
(1997)
J Immunol
, vol.159
, pp. 1344-1351
-
-
Stalder, A.K.1
Pagenstecher, A.2
Yu, N.C.3
Kincaid, C.4
Chiang, C.S.5
Hobbs, M.V.6
Bloom, F.E.7
Campbell, I.L.8
-
31
-
-
33646823302
-
Protein kinase Ca-RhoA cross-talk in CCL2-induced alterations in brain endothelial permeability
-
Stamatovic SM, Dimitrijevic OB, Keep RF, Andjelkovic AV. 2006. Protein kinase Ca-RhoA cross-talk in CCL2-induced alterations in brain endothelial permeability. J Biol Chem 281:8379-8388.
-
(2006)
J Biol Chem
, vol.281
, pp. 8379-8388
-
-
Stamatovic, S.M.1
Dimitrijevic, O.B.2
Keep, R.F.3
Andjelkovic, A.V.4
-
32
-
-
0034062423
-
Staging of multiple sclerosis (MS) lesions: Pathology of the time frame of MS
-
van der Valk P, De Groot CJ. 2000. Staging of multiple sclerosis (MS) lesions: Pathology of the time frame of MS. Neuropathol Appl Neurobiol 26:2-10.
-
(2000)
Neuropathol Appl Neurobiol
, vol.26
, pp. 2-10
-
-
Van Der Valk, P.1
De Groot, C.J.2
-
33
-
-
33745227281
-
NAD(P)H:quinone oxidoreductase 1 expression in multiple sclerosis lesions
-
DOI 10.1016/j.freeradbiomed.2006.04.013, PII S0891584906002565
-
van Horssen J, Schreibelt G, Bo L, Montagne L, Drukarch B, van Muiswinkel FL, De Vries HE. 2006. NAD(P)H:quinone oxidoreductase 1 expression in multiple sclerosis lesions. Free Radic Biol Med 41:311-317. (Pubitemid 43928505)
-
(2006)
Free Radical Biology and Medicine
, vol.41
, Issue.2
, pp. 311-317
-
-
Van Horssen, J.1
Schreibelt, G.2
Bo, L.3
Montagne, L.4
Drukarch, B.5
Van Muiswinkel, F.L.6
De Vries, H.E.7
-
34
-
-
56349160121
-
Severe oxidative damage in multiple sclerosis lesions coincides with enhanced antioxidant enzyme expression
-
Van Horssen J, Schreibelt G, Drexhage J, Hazes T, Dijkstra CD, van der Valk P, De Vries HE. 2008. Severe oxidative damage in multiple sclerosis lesions coincides with enhanced antioxidant enzyme expression. Free Radic Biol Med 45:1729-1737.
-
(2008)
Free Radic Biol Med
, vol.45
, pp. 1729-1737
-
-
Van Horssen, J.1
Schreibelt, G.2
Drexhage, J.3
Hazes, T.4
Dijkstra, C.D.5
Van Der Valk, P.6
De Vries, H.E.7
-
35
-
-
1942422671
-
Distinctive G protein-dependent signaling in smooth muscle by sphingosine 1-phosphate receptors S1P1 and S1P2
-
Zhou H, Murthy KS. 2004. Distinctive G protein-dependent signaling in smooth muscle by sphingosine 1-phosphate receptors S1P1 and S1P2. Am J Physiol Cell Physiol 286:C1130-C1138.
-
(2004)
Am J Physiol Cell Physiol
, vol.286
-
-
Zhou, H.1
Murthy, K.S.2
|