Sphingosine 1-phosphate induces Mcl-1 upregulation and protects multiple myeloma cells against apoptosis

Biochemical and Biophysical Research Communications

Volumn 371, Issue 1, 2008, Pages 159-162

  Li, Qing Fang ^a   Wu, Chu Tse ^a   Guo, Qiang ^b   Wang, Hua ^a   Wang, Li Sheng ^a  

^a BEIJING INSTITUTE OF RADIATION MEDICINE   (China)

^b GENERAL HOSPITAL OF NORTHERN THEATER COMMAND   (China)

Author keywords

Apoptosis; Mcl 1; Multiple myeloma; Sphingosine1 phosphate

Indexed keywords

2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; 5 (4 PHENYL 5 TRIFLUOROMETHYL 2 THIENYL) 3 (3 TRIFLUOROMETHYLPHENYL) 1,2,4 OXADIAZOLE; CAY 10444; JTE 013; N BENZYL 2 CYANO 3 (3,4 DIHYDROXYPHENYL)ACRYLAMIDE; PERTUSSIS TOXIN; PROTEIN MCL 1; PROTEIN TYROSINE KINASE INHIBITOR; SPHINGOSINE 1 PHOSPHATE; SPHINGOSINE 1 PHOSPHATE RECEPTOR; SPHINGOSINE 2 PHOSPHATE; SPHINGOSINE 3 PHOSPHATE; SPHINGOSINE DERIVATIVE; WORTMANNIN;

APOPTOSIS; ARTICLE; CANCER CELL CULTURE; CELL PROTECTION; CELL SURVIVAL; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYTOLYSIS; HUMAN; HUMAN CELL; MULTIPLE MYELOMA; PRIORITY JOURNAL; PROTEIN EXPRESSION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; UPREGULATION; WESTERN BLOTTING;

APOPTOSIS; CELL LINE, TUMOR; HUMANS; LYSOPHOSPHOLIPIDS; MULTIPLE MYELOMA; NEOPLASM PROTEINS; PERTUSSIS TOXIN; PROTO-ONCOGENE PROTEINS C-BCL-2; RECEPTORS, LYSOSPHINGOLIPID; SPHINGOSINE; UP-REGULATION;

EID: 42749092078     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2008.04.037     Document Type: Article

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