Regulation of autophagy and its associated cell death by "sphingolipid rheostat": Reciprocal role of ceramide and sphingosine 1-phosphate in the mammalian target of rapamycin pathway

Journal of Biological Chemistry

Volumn 287, Issue 47, 2012, Pages 39898-39910

  Taniguchi, Makoto ^a,c   Kitatani, Kazuyuki ^a,d   Kondo, Tadakazu ^e   Hashimoto Nishimura, Mayumi ^a,b   Asano, Satoshi ^a,b   Hayashi, Akira ^a,c   Mitsutake, Susumu ^f   Igarashi, Yasuyuki ^f   Umehara, Hisanori ^c   Takeya, Hiroyuki ^a   Kigawa, Junzo ^b   Okazaki, Toshiro ^a,c  

^a TOTTORI UNIVERSITY   (Japan)

^b TOTTORI UNIVERSITY HOSPITAL   (Japan)

^c KANAZAWA MEDICAL UNIVERSITY   (Japan)

^d TOHOKU UNIVERSITY   (Japan)

^e KYOTO UNIVERSITY   (Japan)

^f HOKKAIDO UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

AUTOPHAGY; BIOLOGICAL ACTIONS; CELL SURFACE RECEPTORS; CERAMIDES; CHO CELL; DEPHOSPHORYLATIONS; HL-60 CELLS; MAMMALIAN TARGET; MAMMALIAN TARGET OF RAPAMYCIN (MTOR); OKADAIC ACID; PROTEIN PHOSPHATASE; SPHINGOLIPIDS; SPHINGOSINE 1 PHOSPHATES;

AMINO ACIDS; ANTIBIOTICS; CALCIUM ION SENSORS; CELL DEATH; CELL MEMBRANES;

AMIDES;

CELL SURFACE RECEPTOR; CERAMIDE; CERAMIDE ACTIVATED PROTEIN PHOSPHATASE; MAMMALIAN TARGET OF RAPAMYCIN; N ACETYLSPHINGOSINE; OKADAIC ACID; PHOSPHOPROTEIN PHOSPHATASE; SPHINGOLIPID; SPHINGOMYELIN PHOSPHODIESTERASE; SPHINGOSINE; SPHINGOSINE 1 PHOSPHATE; SPHINGOSINE 1 PHOSPHATE RECEPTOR; SPHINGOSINE 1 PHOSPHATE RECEPTOR 3; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; AUTOPHAGOSOME; AUTOPHAGY; CELL DEATH; CELL STRAIN HL 60; CHO CELL; CONTROLLED STUDY; ENZYME INACTIVATION; HUMAN; HUMAN CELL; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEPHOSPHORYLATION; SIGNAL TRANSDUCTION;

ANIMALS; AUTOPHAGY; CERAMIDES; CHO CELLS; CRICETINAE; CRICETULUS; GENE KNOCKDOWN TECHNIQUES; HL-60 CELLS; HUMANS; LYSOPHOSPHOLIPIDS; PHOSPHOPROTEIN PHOSPHATASES; PHOSPHORYLATION; RECEPTORS, LYSOSPHINGOLIPID; SIGNAL TRANSDUCTION; SPHINGOMYELIN PHOSPHODIESTERASE; SPHINGOSINE; TOR SERINE-THREONINE KINASES;

MAMMALIA;

EID: 84869208878     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M112.416552     Document Type: Article

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