Sphingosine kinases/sphingosine-1-phosphate and death signalling in APP-transfected cells

Neurochemical Research

Volumn 39, Issue 4, 2014, Pages 645-652

  Gassowska, Magdalena ^a   Cieslik, Magdalena ^a   Wilkaniec, Anna ^a   Strosznajder, Joanna B ^a  

^a MOSSAKOWSKI MEDICAL RESEARCH CENTRE   (Poland)

Author keywords

Alzheimer's disease; Amyloid peptides; Dopaminergic cells; Sphingolipids; Sphingosine kinases; Sphingosine 1 phosphate

Indexed keywords

5 (4 PHENYL 5 TRIFLUOROMETHYL 2 THIENYL) 3 (3 TRIFLUOROMETHYLPHENYL) 1,2,4 OXADIAZOLE; AMYLOID BETA PRECURSOR PROTEIN; AMYLOID BETA PROTEIN; AMYLOID PRECURSOR PROTEIN; SPHINGOSINE 1 PHOSPHATE; SPHINGOSINE 1 PHOSPHATE RECEPTOR; SPHINGOSINE 1 PHOSPHATE RECEPTOR 1; SPHINGOSINE KINASE 1; SPHINGOSINE KINASE 2; UNCLASSIFIED DRUG; ENZYME INHIBITOR; LYSOPHOSPHOLIPID; PHOSPHOTRANSFERASE; SPHINGOSINE; SPHINGOSINE 1-PHOSPHATE; SPHINGOSINE KINASE;

ANIMAL CELL; ARTICLE; CELL DEATH; CELL PROTECTION; CELL SURVIVAL; CELL VIABILITY; CONTROLLED STUDY; ENZYME ACTIVITY; GENETIC TRANSFECTION; IMMUNOREACTIVITY; IN VITRO STUDY; MTT ASSAY; NONHUMAN; POLYACRYLAMIDE GEL ELECTROPHORESIS; PRIORITY JOURNAL; PROTEIN EXPRESSION; QUANTITATIVE ANALYSIS; RAT; REAL TIME POLYMERASE CHAIN REACTION; WESTERN BLOTTING; ANALOGS AND DERIVATIVES; ANIMAL; ANTAGONISTS AND INHIBITORS; BIOSYNTHESIS; DRUG EFFECTS; HUMAN; PC12 CELL LINE; PHYSIOLOGY; PROCEDURES; SIGNAL TRANSDUCTION;

AMYLOID BETA-PROTEIN PRECURSOR; ANIMALS; CELL SURVIVAL; ENZYME INHIBITORS; HUMANS; LYSOPHOSPHOLIPIDS; PC12 CELLS; PHOSPHOTRANSFERASES (ALCOHOL GROUP ACCEPTOR); RATS; SIGNAL TRANSDUCTION; SPHINGOSINE; TRANSFECTION;

EID: 84898897679     PISSN: 03643190     EISSN: 15736903     Source Type: Journal    
DOI: 10.1007/s11064-014-1240-3     Document Type: Article

References (44)

1. Haughey NJ, Bandaru VVR, Bae M, Mattson MP (2010) Roles for dysfunctional sphingolipid metabolism in Alzheimer's disease neuropathogenesis. Biochim Biophys Acta 1801:878-886
2. Katsel P, Li C, Haroutunian V (2007) Gene expression alterations in the sphingolipid metabolism pathways during progression of dementia and Alzheimer's disease: a shift toward ceramide accumulation at the earliest recognizable stages of Alzheimer's disease? Neurochem Res 32:845-856
3. Fukuda Y, Kihara A, Igarashi Y (2003) Distribution of sphingosine kinase activity in mouse tissues: contribution of SPHK1. Biochem Biophys Res Commun 309(1):155-160
4. Muller G, Ayoub M, Storz P, Rennecke J, Fabbro D, Pfizenmaier K (1995) PKC is a molecular switch in signal transduction of TNF-a, bifunctionally regulated by ceramide and arachidonic acid. EMBO J 14:1961-1969
5. Riboni L, Viani P, Bassi R, Giussani P, Tettamanti G (2001) Basic fibroblast growth factor-induced proliferation of primary astrocytes. Evidence for the involvement of sphingomyelin biosynthesis. J Biol Chem 276:12797-12804
6. Pettus BJ, Chalfant CE, Hannun YA (2002) Ceramide in apoptosis: an overview and current perspectives. Biochim Biophys Acta 1585:114-125
7. Alvarez SE, Milstien Sh, Spiegel S (2007) Autocrine and paracrine roles of sphingosine-1-phosphate. Trends Endocrinol Metab 18:300-307
8. Pyne NJ, Pyne S (2010) Sphongosine 1-phosphate and cancer. Nat Rev Cancer 10:489-503
9. Van Brocklyn JR, Lee MJ, Menzeleev R, Olivera A, Edsall L, Cuvillier O, Thomas DM, Coopman PJ, Thangada S, Liu CH, Hla T, Spiegel S (1998) Dual actions of sphingosine-1-phosphate: extracellular through the Gi-coupled receptor Edg-1 and intracellular to regulate proliferation and survival. J Cell Biol 142:229-240
10. Pitson SM (2011) Regulation of sphingosine kinase and sphingolipid signaling. Trends Biochem Sci 36:97-107
11. Hait NC, Allegood J, Maceyka M, Strub GM, Harikumar KB, Singh SK, Luo C, Marmorstein R, Kordula T, Milstien S, Spiegel S (2009) Regulation of histone acetylation in the nucleus by sphingosine-1-phosphate. Science 325:1254-1257
12. Alvarez SE, Harikumar KB, Hait NC, Allegood J, Strub GM, Kim EY, Maceyka M, Jiang H, Luo C, Kordula T, Milstien S, Spiegel S (2010) Sphingosine-1- phosphate is a missing cofactor for the E3 ubiquitin ligase TRAF2. Nature 465(7301):1084-1088
13. Hagen N, Hans M, Hartmann D, Swandulla D, Van Echten-Deckert G (2011) Sphingosine-1-phosphate links glycosphingolipid metabolism to neurodegeneration via a calpain-mediated mechanism. Cell Death Differ 18:1356-1365
14. Hannun YA, Obeid LM (2008) Principles of bioactive lipid signalling: lessons from sphingolipids. Nat Rev Mol Cell Biol 9(2):139-150
15. Meyer zu, Heringdorf D, Jakobs KH (2007) Lysophospholipid receptors: signalling, pharmacology and regulation by lysophospholipid metabolism. Biochim Biophys Acta 1768:923-940
16. Edsall LC, Cuvillier O, Twitty Sh, Spiegel S, Milstien Sh (2001) Sphingosine kinase expression regulates apoptosis and caspase activation in PC12 cells. J Neurochem 76:1573-1584
17. Takasugi N, Sasaki T, Suzuki K, Osawa S, Isshiki H, Hori Y, Shimada N, Higo T, Yokoshima S, Fukuyama T, Lee V, Trojanowski JQ, Tomita T, Iwatsubo T (2011) BACE1 activity is modulated by cell-associated sphingosine-1-phosphate. J Neurosci 31(18):6850-6857
18. Maceyka M, Sankala H, Hait NC et al (2005) Sphk1 and Sphk2: sphingosine kinase isoenzymes with opposing functions in sphingolipid metabolism. J Biol Chem 280:37118-37129
19. Strub GM, Maceykaa M, Hait NC, Milstienb S, Spiegel S (2010) Extracellular and intracellular actions of sphingosine-1-phosphate. Adv Exp Med Biol 688:141-155
20. Epis R, Marcello E, Gardoni F, Di Luca M (2012) Alpha, beta-and gamma-secretases in Alzheimer's disease. Front Biosci (Schol Ed) 4:1126-1150
21. Zinser EG, Hartmann T, Grimm MOW (2007) Amyloid beta-protein and lipid metabolism. Biochim Biophys Acta 1768:1991-2001
22. Van Echten-Deckert G, Walter J (2012) Sphingolipids: critical players in Alzheimer's disease. Prog Lipid Res 51:378-393
23. Lütjohann D, Meichsner S, Pettersson H (2012) Lipids in Alzheimer's disease and their potential for therapy. Discl Clin Lipidol 7(1):65-78
24. Grimm MOW, Rothhaar TL, Hartmann T (2012) The role of APP proteolytic processing in lipid metabolism. Exp Brain Res 217:365-375
25. Tamboli IY, Prager K, Barth E, Heneka M, Sandhoff K, Walter J (2005) Inhibition of glycosphingolipid biosynthesis reduces secretion of the β-amyloid precursor protein and amyloid β-peptide. J Biol Chem 280(30):28110-28117
26. Grimm MOW, Grimm HS, Hartmann T (2007) Amyloid beta as a regulator of lipid homeostasis. Trends Mol Med 13(8):337-344
27. Billich A, Ettmayer P (2004) Fluorescence-based assay of sphingosine kinases. Anal Biochem 326(1):114-119
28. Chalimoniuk M, Stolecka A, Cakała M, Hauptmann S, Shulz K, Lipka U, Leuner K, Eckert A, Muller WE, Strosznajder BJ (2007) Amyloid beta enhances cytosolic phospholipase A2 level and arachidonic acid release via nitric oxide in APP-transfected PC12 cells. Acta Biochim Pol 54(3):611-623
29. Paja̧k B, Songin M, Strosznajder BJ, Orzechowski A, Gajkowska B (2009) Ultrastructural evidence of amyloid β-induced autophagy in PC12 cells. Folia Neuropathol 47(3):252-258
30. Gomez-Brouchet A, Pchejetski D, Brizuela L, Garcia V, Altie' M-F, Maddelein M-L, Delisle M-B, Cuvillier O (2007) Critical role for sphingosine kinase-1 in regulating survival of neuroblastoma cells exposed to amyloid-β peptide. Mol Pharmacol 72:341-349
31. Olivera A, Spiegel S (2001) Sphingosine kinase: a mediator of vital cellular functions. Prostaglandins Lipid Med 64:123-134
32. Young KW, Willets JM, Parkinson MJ, Bartlett P, Spiegel S, Nahorski SR, Challiss RA (2003) Ca2/calmodulin-dependent translocation of sphingosine kinase: role in plasma membrane relocation but not activation. Cell Calcium 33:119-128
33. Jolly PS, Bektas M, Watterson KR, Sankala H, Payne SG, Milstien S, Spiegel S (2005) Expression of SphK1 impairs degranulation and motility of RBL-2H3 mast cells by desensitizing S1P receptors. Blood 105(12):4736-4742
34. Wattenberg BW, Pitson SM, Raben DM (2006) The sphingosine and diacylglycerol kinase superfamily of signaling kinases: localization as a key to signalling function. J Lipid Res 47:1128-1139
35. 2+ release mediator in the balance. Cell Calcium 32:335-341
36. Olivera A, Kohama T, Edsall L, Nava V, Cuvillier O, Poulton S, Spiegel S (1999) Sphingosine kinase expression increases intracellular sphingosine-1-phosphate and promotes cell growth and survival. J Cell Biol 147(3):545-558
37. Nava VE, Cuvillier O, Edsall LC, Kimura K, Milstien S, Gelmann EP, Spiegel S (2000) Sphingosine enhances apoptosis of radiation-resistant prostate cancer cells. Cancer Res 60:4468-4474
38. Taha TA, Osta W, Kozhaya L, Bielawski J, Johnson KR, Gillanders WE, Dbaibo GS, Hannun YA, Obeid LM (2004) Down-regulation of sphingosine kinase-1 by DNA damage: dependence on proteases and p53. J Biol Chem 279:20546-20554
39. Pchejetski D, Golzio M, Bonhoure E, Calvet C, Doumerc N, Garcia V, Mazerolles C, Rischmann P, Teissie J, Malavaud B et al (2005) Sphingosine kinase-1 as a chemotherapy sensor in prostate adenocarcinoma cell and mouse models. Cancer Res 65:11667-11675
40. Bonhoure E, Pchejetski D, Aouali N, Morjani H, Levade T, Kohama T, Cuvillier O (2006) Overcoming MDR-associated chemoresistance in HL-60 acute myeloid leukemia cells by targeting sphingosine kinase-1. Leukemia 20:95-102
41. Takabe K, Paugh SW, Milstein S, Spiegel S (2008) "Inside-out" signalling of sphingosine-1-phosphate: therapeutic targets. Pharmacol Rev 60:181-195
42. Ozaki H, Hla T, Lee MJ (2003) Sphingosine-1-phosphate signaling in endothelial activation. J Atheroscler Thromb 10:125-131
43. Rosen H, Goetzl EJ (2005) Sphingosine 1-phosphate and its receptors: an autocrine and paracrine network. Nat Rev Immunol 5:560-570
44. Kaneider NC, Lindner J, Feistritzer C, Sturn DH, Mosheimer BA, Djanani AM, Wiedermann ChJ (2004) The immune modulator FTY720 targets sphingosine-kinase dependent migration of human monocytes in response to amyloid beta-protein and its precursor. FASEB J 18(11):1309-1311