-
1
-
-
0034093521
-
EDG receptors as a therapeutic target in the nervous system
-
Beer M. S., Stanton J. A., Salim K., Rigby M., Heavens R. P., Smith D. McAllister G. (2000) EDG receptors as a therapeutic target in the nervous system. Ann. NY Acad. Sci. 905, 118 131.
-
(2000)
Ann. NY Acad. Sci.
, vol.905
, pp. 118-131
-
-
Beer, M.S.1
Stanton, J.A.2
Salim, K.3
Rigby, M.4
Heavens, R.P.5
Smith, D.6
McAllister, G.7
-
3
-
-
34848826331
-
Distribution of sphingosine kinase activity and mRNA in rodent brain
-
Blondeau N., Lai Y., Tyndall S. et al. (2007) Distribution of sphingosine kinase activity and mRNA in rodent brain. J. Neurochem. 103, 509 517.
-
(2007)
J. Neurochem.
, vol.103
, pp. 509-517
-
-
Blondeau, N.1
Lai, Y.2
Tyndall, S.3
-
4
-
-
34250832664
-
Sphingosine 1-phosphate receptors in health and disease: Mechanistic insights from gene deletion studies and reverse pharmacology
-
Brinkmann V. (2007) Sphingosine 1-phosphate receptors in health and disease: mechanistic insights from gene deletion studies and reverse pharmacology. Pharmacol. Ther. 115, 84 105.
-
(2007)
Pharmacol. Ther.
, vol.115
, pp. 84-105
-
-
Brinkmann, V.1
-
6
-
-
49949116576
-
Biological roles of lysophospholipid receptors revealed by genetic null mice: An update
-
Choi J. W., Lee C. W. Chun J. (2008) Biological roles of lysophospholipid receptors revealed by genetic null mice: an update. Biochim. Biophys. Acta. 1781, 531 539.
-
(2008)
Biochim. Biophys. Acta.
, vol.1781
, pp. 531-539
-
-
Choi, J.W.1
Lee, C.W.2
Chun, J.3
-
7
-
-
0036266101
-
International Union of Pharmacology. XXXIV. Lysophospholipid receptor nomenclature.
-
Chun J., Goetzl E. J., Hla T., Igarashi Y., Lynch K. R., Moolenaar W., Pyne S. Tigyi G. (2002) International Union of Pharmacology. XXXIV. Lysophospholipid receptor nomenclature. Pharmacol. Rev. 54, 265 269.
-
(2002)
Pharmacol. Rev.
, vol.54
, pp. 265-269
-
-
Chun, J.1
Goetzl, E.J.2
Hla, T.3
Igarashi, Y.4
Lynch, K.R.5
Moolenaar, W.6
Pyne, S.7
Tigyi, G.8
-
8
-
-
0027501457
-
Cannabinoid structure-activity relationships: Correlation of receptor binding and in vivo activities
-
Compton D. R., Rice K. C., DeCosta B. R., Razdan R. K., Melvin L. S., Johnson M. R. Martin B. R. (1993) Cannabinoid structure-activity relationships: correlation of receptor binding and in vivo activities. J. Pharmacol. Exp. Ther. 265, 218 226.
-
(1993)
J. Pharmacol. Exp. Ther.
, vol.265
, pp. 218-226
-
-
Compton, D.R.1
Rice, K.C.2
Decosta, B.R.3
Razdan, R.K.4
Melvin, L.S.5
Johnson, M.R.6
Martin, B.R.7
-
9
-
-
44149098856
-
Antinociceptive activity of the S1P-receptor agonist FTY720
-
Coste O., Pierre S., Marian C., Brenneis C., Angioni C., Schmidt H., Popp L., Geisslinger G. Scholich K. (2008) Antinociceptive activity of the S1P-receptor agonist FTY720. J. Cell Mol. Med. 12, 995 1004.
-
(2008)
J. Cell Mol. Med.
, vol.12
, pp. 995-1004
-
-
Coste, O.1
Pierre, S.2
Marian, C.3
Brenneis, C.4
Angioni, C.5
Schmidt, H.6
Popp, L.7
Geisslinger, G.8
Scholich, K.9
-
10
-
-
0002261078
-
A method for determining the loss of pain sensation
-
D'Amour F. E. Smith D. C. (1941) A method for determining the loss of pain sensation. J. Pharmacol. Exp. Ther. 72, 74 79.
-
(1941)
J. Pharmacol. Exp. Ther.
, vol.72
, pp. 74-79
-
-
D'Amour, F.E.1
Smith, D.C.2
-
11
-
-
0033566208
-
Enzymatic measurement of sphingosine 1-phosphate
-
Edsall L. C. Spiegel S. (1999) Enzymatic measurement of sphingosine 1-phosphate. Anal. Biochem. 272, 80 86.
-
(1999)
Anal. Biochem.
, vol.272
, pp. 80-86
-
-
Edsall, L.C.1
Spiegel, S.2
-
12
-
-
33845296479
-
Synthesis and biological evaluation of gamma-aminophosphonates as potent, subtype-selective sphingosine 1-phosphate receptor agonists and antagonists
-
Foss F. W. Jr., Snyder A. H., Davis M. D., Rouse M., Okusa M. D., Lynch K. R. Macdonald T. L. (2007) Synthesis and biological evaluation of gamma-aminophosphonates as potent, subtype-selective sphingosine 1-phosphate receptor agonists and antagonists. Bioorg. Med. Chem. 15, 663 677.
-
(2007)
Bioorg. Med. Chem.
, vol.15
, pp. 663-677
-
-
Foss, Jr.F.W.1
Snyder, A.H.2
Davis, M.D.3
Rouse, M.4
Okusa, M.D.5
Lynch, K.R.6
MacDonald, T.L.7
-
13
-
-
0033198298
-
Enhancement of AMPA-mediated current after traumatic injury in cortical neurons
-
Goforth P. B., Ellis E. F. Satin L. S. (1999) Enhancement of AMPA-mediated current after traumatic injury in cortical neurons. J. Neurosci. 19, 7367 7374.
-
(1999)
J. Neurosci.
, vol.19
, pp. 7367-7374
-
-
Goforth, P.B.1
Ellis, E.F.2
Satin, L.S.3
-
14
-
-
0019441262
-
Improved patch-clamp techniques for high-resolution current recording from cells and cell-free membrane patches
-
Hamill O. P., Marty A., Neher E., Sakmann B. Sigworth F. J. (1981) Improved patch-clamp techniques for high-resolution current recording from cells and cell-free membrane patches. Pflugers Arch. 391, 85 100.
-
(1981)
Pflugers Arch.
, vol.391
, pp. 85-100
-
-
Hamill, O.P.1
Marty, A.2
Neher, E.3
Sakmann, B.4
Sigworth, F.J.5
-
15
-
-
0000977039
-
Some narcotic antagonists in the benzomorphan series
-
Harris L. S. Pierson A. K. (1964) Some narcotic antagonists in the benzomorphan series. J. Pharmacol. Exp. Ther. 143, 141 148.
-
(1964)
J. Pharmacol. Exp. Ther.
, vol.143
, pp. 141-148
-
-
Harris, L.S.1
Pierson, A.K.2
-
16
-
-
0025954862
-
Characterization and localization of cannabinoid receptors in rat brain: A quantitative in vitro autoradiographic study
-
Herkenham M., Lynn A. B., Johnson M. R., Melvin L. S., de Costa B. R. Rice K. C. (1991) Characterization and localization of cannabinoid receptors in rat brain: a quantitative in vitro autoradiographic study. J. Neurosci. 11, 563 583.
-
(1991)
J. Neurosci.
, vol.11
, pp. 563-583
-
-
Herkenham, M.1
Lynn, A.B.2
Johnson, M.R.3
Melvin, L.S.4
De Costa, B.R.5
Rice, K.C.6
-
17
-
-
0022477611
-
Primary culture of identified neurons from the visual cortex of postnatal rats
-
Huettner J. E. Baughman R. W. (1986) Primary culture of identified neurons from the visual cortex of postnatal rats. J. Neurosci. 6, 3044 3060.
-
(1986)
J. Neurosci.
, vol.6
, pp. 3044-3060
-
-
Huettner, J.E.1
Baughman, R.W.2
-
18
-
-
0035823477
-
Selective loss of sphingosine 1-phosphate signaling with no obvious phenotypic abnormality in mice lacking its G protein-coupled receptor, LP(B3)/EDG-3
-
Ishii I., Friedman B., Ye X., Kawamura S., McGiffert C., Contos J. J., Kingsbury M. A., Zhang G., Brown J. H. Chun J. (2001) Selective loss of sphingosine 1-phosphate signaling with no obvious phenotypic abnormality in mice lacking its G protein-coupled receptor, LP(B3)/EDG-3. J. Biol. Chem. 276, 33697 33704.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 33697-33704
-
-
Ishii, I.1
Friedman, B.2
Ye, X.3
Kawamura, S.4
McGiffert, C.5
Contos, J.J.6
Kingsbury, M.A.7
Zhang, G.8
Brown, J.H.9
Chun, J.10
-
19
-
-
34247552132
-
Involvement of sphingosine-1-phosphate in glutamate secretion in hippocampal neurons
-
Kajimoto T., Okada T., Yu H., Goparaju S. K., Jahangeer S. Nakamura S. (2007) Involvement of sphingosine-1-phosphate in glutamate secretion in hippocampal neurons. Mol. Cell. Biol. 27, 3429 3440.
-
(2007)
Mol. Cell. Biol.
, vol.27
, pp. 3429-3440
-
-
Kajimoto, T.1
Okada, T.2
Yu, H.3
Goparaju, S.K.4
Jahangeer, S.5
Nakamura, S.6
-
20
-
-
0027426051
-
Evidence that the antinociceptive tail-flick response is produced independently from changes in either tail-skin temperature or core temperature
-
Lichtman A. H., Smith F. L. Martin B. R. (1993) Evidence that the antinociceptive tail-flick response is produced independently from changes in either tail-skin temperature or core temperature. Pain 55, 283 295.
-
(1993)
Pain
, vol.55
, pp. 283-295
-
-
Lichtman, A.H.1
Smith, F.L.2
Martin, B.R.3
-
21
-
-
0033783522
-
Edg-1, the G protein-coupled receptor for sphingosine-1-phosphate, is essential for vascular maturation
-
Liu Y., Wada R., Yamashita T. et al. (2000) Edg-1, the G protein-coupled receptor for sphingosine-1-phosphate, is essential for vascular maturation. J. Clin. Invest. 106, 951 961.
-
(2000)
J. Clin. Invest.
, vol.106
, pp. 951-961
-
-
Liu, Y.1
Wada, R.2
Yamashita, T.3
-
22
-
-
51749114831
-
Sphingosine 1-phosphate chemical biology
-
Lynch K. R. Macdonald T. L. (2008) Sphingosine 1-phosphate chemical biology. Biochim. Biophys. Acta 1781, 508 512.
-
(2008)
Biochim. Biophys. Acta
, vol.1781
, pp. 508-512
-
-
Lynch, K.R.1
MacDonald, T.L.2
-
23
-
-
0034887535
-
An essential role for the H218/AGR16/Edg-5/LP(B2) sphingosine 1-phosphate receptor in neuronal excitability
-
MacLennan A. J., Carney P. R., Zhu W. J., Chaves A. H., Garcia J., Grimes J. R., Anderson K. J., Roper S. N. Lee N. (2001) An essential role for the H218/AGR16/Edg-5/LP(B2) sphingosine 1-phosphate receptor in neuronal excitability. Eur. J. Neurosci. 14, 203 209.
-
(2001)
Eur. J. Neurosci.
, vol.14
, pp. 203-209
-
-
MacLennan, A.J.1
Carney, P.R.2
Zhu, W.J.3
Chaves, A.H.4
Garcia, J.5
Grimes, J.R.6
Anderson, K.J.7
Roper, S.N.8
Lee, N.9
-
24
-
-
0037066466
-
Alteration of lymphocyte trafficking by sphingosine-1-phosphate receptor agonists
-
Mandala S., Hajdu R., Bergstrom J. et al. (2002) Alteration of lymphocyte trafficking by sphingosine-1-phosphate receptor agonists. Science 296, 346 349.
-
(2002)
Science
, vol.296
, pp. 346-349
-
-
Mandala, S.1
Hajdu, R.2
Bergstrom, J.3
-
25
-
-
63849147004
-
Oral fingolimod (FTY720) in multiple sclerosis: Two-year results of a phase II extension study
-
O'Connor P., Comi G., Montalban X., Antel J., Radue E. W., de Vera A., Pohlmann H. Kappos L. (2009) Oral fingolimod (FTY720) in multiple sclerosis: two-year results of a phase II extension study. Neurology 72, 73 79.
-
(2009)
Neurology
, vol.72
, pp. 73-79
-
-
O'Connor, P.1
Comi, G.2
Montalban, X.3
Antel, J.4
Radue, E.W.5
De Vera, A.6
Pohlmann, H.7
Kappos, L.8
-
26
-
-
33745255388
-
Sphingosine and its analog, the immunosuppressant 2-amino-2-(2-[4- octylphenyl]ethyl)-1,3-propanediol, interact with the CB1 cannabinoid receptor
-
Paugh S. W., Cassidy M. P., He H., Milstien S., Sim-Selley L. J., Spiegel S. Selley D. E. (2006) Sphingosine and its analog, the immunosuppressant 2-amino-2-(2-[4-octylphenyl]ethyl)-1,3-propanediol, interact with the CB1 cannabinoid receptor. Mol. Pharmacol. 70, 41 50.
-
(2006)
Mol. Pharmacol.
, vol.70
, pp. 41-50
-
-
Paugh, S.W.1
Cassidy, M.P.2
He, H.3
Milstien, S.4
Sim-Selley, L.J.5
Spiegel, S.6
Selley, D.E.7
-
27
-
-
33846864904
-
The immunosuppressant drug FTY720 inhibits cytosolic phospholipase A2 independently of sphingosine-1-phosphate receptors
-
Payne S. G., Oskeritzian C. A., Griffiths R., Subramanian P., Barbour S. E., Chalfant C. E., Milstien S. Spiegel S. (2007) The immunosuppressant drug FTY720 inhibits cytosolic phospholipase A2 independently of sphingosine-1- phosphate receptors. Blood 109, 1077 1085.
-
(2007)
Blood
, vol.109
, pp. 1077-1085
-
-
Payne, S.G.1
Oskeritzian, C.A.2
Griffiths, R.3
Subramanian, P.4
Barbour, S.E.5
Chalfant, C.E.6
Milstien, S.7
Spiegel, S.8
-
28
-
-
0016513490
-
Determination and characterization of the antinociceptive activity of intraventricularly administered acetylcholine in mice
-
Pedigo N. W., Dewey W. L. Harris L. S. (1975) Determination and characterization of the antinociceptive activity of intraventricularly administered acetylcholine in mice. J. Pharmacol. Exp. Ther. 193, 845 852.
-
(1975)
J. Pharmacol. Exp. Ther.
, vol.193
, pp. 845-852
-
-
Pedigo, N.W.1
Dewey, W.L.2
Harris, L.S.3
-
29
-
-
0015445325
-
The ring test: A quantitative method for assessing the 'cataleptic' effect of cannabis in mice
-
Pertwee R. G. (1972) The ring test: a quantitative method for assessing the 'cataleptic' effect of cannabis in mice. Br. J. Pharmacol. 46, 753 763.
-
(1972)
Br. J. Pharmacol.
, vol.46
, pp. 753-763
-
-
Pertwee, R.G.1
-
30
-
-
11144353922
-
Sphingosine 1-phosphate (S1P) receptor subtypes S1P1 and S1P3, respectively, regulate lymphocyte recirculation and heart rate
-
Sanna M. G., Liao J., Jo E. et al. (2004) Sphingosine 1-phosphate (S1P) receptor subtypes S1P1 and S1P3, respectively, regulate lymphocyte recirculation and heart rate. J. Biol. Chem. 279, 13839 13848.
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 13839-13848
-
-
Sanna, M.G.1
Liao, J.2
Jo, E.3
-
33
-
-
0034733910
-
Sphingosine-1-phosphate: Signaling inside and out
-
Spiegel S. Milstien S. (2000) Sphingosine-1-phosphate: signaling inside and out. FEBS Lett. 476, 55 57.
-
(2000)
FEBS Lett.
, vol.476
, pp. 55-57
-
-
Spiegel, S.1
Milstien, S.2
-
34
-
-
0038218405
-
Sphingosine-1-phosphate: An enigmatic signalling lipid
-
Spiegel S. Milstien S. (2003) Sphingosine-1-phosphate: an enigmatic signalling lipid. Nat. Rev. Mol. Cell Biol. 4, 397 407.
-
(2003)
Nat. Rev. Mol. Cell Biol.
, vol.4
, pp. 397-407
-
-
Spiegel, S.1
Milstien, S.2
-
35
-
-
46949104885
-
"inside-out" signaling of sphingosine-1-phosphate: Therapeutic targets
-
Takabe K., Paugh S. W., Milstien S. Spiegel S. (2008) "Inside-out" signaling of sphingosine-1-phosphate: therapeutic targets. Pharmacol. Rev. 60, 181 195.
-
(2008)
Pharmacol. Rev.
, vol.60
, pp. 181-195
-
-
Takabe, K.1
Paugh, S.W.2
Milstien, S.3
Spiegel, S.4
-
36
-
-
0345578701
-
Edg-8 receptors are preferentially expressed in oligodendrocyte lineage cells of the rat CNS
-
Terai K., Soga T., Takahashi M., Kamohara M., Ohno K., Yatsugi S., Okada M. Yamaguchi T. (2003) Edg-8 receptors are preferentially expressed in oligodendrocyte lineage cells of the rat CNS. Neuroscience 116, 1053 1062.
-
(2003)
Neuroscience
, vol.116
, pp. 1053-1062
-
-
Terai, K.1
Soga, T.2
Takahashi, M.3
Kamohara, M.4
Ohno, K.5
Yatsugi, S.6
Okada, M.7
Yamaguchi, T.8
-
37
-
-
0036695390
-
Lysophospholipid receptors in the nervous system
-
Toman R. E. Spiegel S. (2002) Lysophospholipid receptors in the nervous system. Neurochem. Res. 27, 619 627.
-
(2002)
Neurochem. Res.
, vol.27
, pp. 619-627
-
-
Toman, R.E.1
Spiegel, S.2
-
38
-
-
0032842039
-
35S]thio)triphosphate binding stimulated by sphingosine 1-phosphate and lysophosphatidic acid
-
35S]thio)triphosphate binding stimulated by sphingosine 1-phosphate and lysophosphatidic acid. J. Neurochem. 73, 1212 1221.
-
(1999)
J. Neurochem.
, vol.73
, pp. 1212-1221
-
-
Waeber, C.1
Chiu, M.L.2
-
39
-
-
33746850399
-
Sphingosine-1-phosphate via excitation of a G-protein-coupled receptor(s) enhances the excitability of rat sensory neurons
-
Zhang Y. H., Fehrenbacher J. C., Vasko M. R. Nicol G. D. (2006) Sphingosine-1-phosphate via excitation of a G-protein-coupled receptor(s) enhances the excitability of rat sensory neurons. J. Neurophysiol. 96, 1042 1052.
-
(2006)
J. Neurophysiol.
, vol.96
, pp. 1042-1052
-
-
Zhang, Y.H.1
Fehrenbacher, J.C.2
Vasko, M.R.3
Nicol, G.D.4
|