-
1
-
-
0036789093
-
Mechanisms and consequences of somatic mosaicism in humans
-
Youssoufian, H., Pyeritz, R. E. Mechanisms and consequences of somatic mosaicism in humans. Nat. Rev. Genet. 3, 748-758 (2002).
-
(2002)
Nat. Rev. Genet.
, vol.3
, pp. 748-758
-
-
Youssoufian, H.1
Pyeritz, R.E.2
-
2
-
-
84882837534
-
Signatures of mutational processes in human cancer
-
Alexandrov, L. B. et al. Signatures of mutational processes in human cancer. Nature 500, 415-421 (2013).
-
(2013)
Nature
, vol.500
, pp. 415-421
-
-
Alexandrov, L.B.1
-
3
-
-
0025312728
-
A genetic model for colorectal tumorigenesis
-
Fearon, E. R., Vogelstein, B. A genetic model for colorectal tumorigenesis. Cell 61, 759-767 (1990).
-
(1990)
Cell
, vol.61
, pp. 759-767
-
-
Fearon, E.R.1
Vogelstein, B.2
-
4
-
-
84861550476
-
The life history of 21 breast cancers
-
Nik-Zainal, S. et al. The life history of 21 breast cancers. Cell 149, 994-1007 (2012).
-
(2012)
Cell
, vol.149
, pp. 994-1007
-
-
Nik-Zainal, S.1
-
5
-
-
84907737648
-
Genome sequencing of normal cells reveals developmental lineages and mutational processes
-
Behjati, S. et al. Genome sequencing of normal cells reveals developmental lineages and mutational processes. Nature 513, 422-425 (2014).
-
(2014)
Nature
, vol.513
, pp. 422-425
-
-
Behjati, S.1
-
6
-
-
0017167185
-
The clonal evolution of tumor cell populations
-
Nowell, P. C. The clonal evolution of tumor cell populations. Science 194, 23-28 (1976).
-
(1976)
Science
, vol.194
, pp. 23-28
-
-
Nowell, P.C.1
-
7
-
-
34047096557
-
Cancer stem cells: Models and concepts
-
Dalerba, P., Cho, R. W., Clarke, M. F. Cancer stem cells: models and concepts. Annu. Rev. Med. 58, 267-284 (2007).
-
(2007)
Annu. Rev. Med.
, vol.58
, pp. 267-284
-
-
Dalerba, P.1
Cho, R.W.2
Clarke, M.F.3
-
8
-
-
58149380742
-
Stem cell concepts renew cancer research
-
Dick, J. E. Stem cell concepts renew cancer research. Blood 112, 4793-4807 (2008).
-
(2008)
Blood
, vol.112
, pp. 4793-4807
-
-
Dick, J.E.1
-
9
-
-
34548073546
-
Genomic variability within an organism exposes its cell lineage tree
-
Frumkin, D., Wasserstrom, A., Kaplan, S., Feige, U., Shapiro, E. Genomic variability within an organism exposes its cell lineage tree. PLoS Comput. Biol. 1, e50 (2005).
-
(2005)
PLoS Comput. Biol.
, vol.1
, pp. e50
-
-
Frumkin, D.1
Wasserstrom, A.2
Kaplan, S.3
Feige, U.4
Shapiro, E.5
-
10
-
-
75749103383
-
Rate molecular spectrum, and consequences of human mutation
-
Lynch, M. Rate, molecular spectrum, and consequences of human mutation. Proc. Natl Acad. Sci. USA 107, 961-968 (2010).
-
(2010)
Proc. Natl Acad. Sci. USA
, vol.107
, pp. 961-968
-
-
Lynch, M.1
-
11
-
-
38049125552
-
The fidelity of DNA synthesis by eukaryotic replicative and translesion synthesis polymerases
-
McCulloch, S. D., Kunkel, T. A. The fidelity of DNA synthesis by eukaryotic replicative and translesion synthesis polymerases. Cell Res. 18, 148-161 (2008).
-
(2008)
Cell Res.
, vol.18
, pp. 148-161
-
-
McCulloch, S.D.1
Kunkel, T.A.2
-
12
-
-
84887983173
-
An estimation of the number of cells in the human body
-
Bianconi, E. et al. An estimation of the number of cells in the human body. Ann. Hum. Biol. 40, 463-471 (2013).
-
(2013)
Ann. Hum. Biol.
, vol.40
, pp. 463-471
-
-
Bianconi, E.1
-
13
-
-
84879756120
-
Somatic mutation, genomic variation, and neurological disease
-
Poduri, A., Evrony, G. D., Cai, X., Walsh, C. A. Somatic mutation, genomic variation, and neurological disease. Science 341, 1237758 (2013).
-
(2013)
Science
, vol.341
, pp. 1237758
-
-
Poduri, A.1
Evrony, G.D.2
Cai, X.3
Walsh, C.A.4
-
14
-
-
50849102293
-
A catalog of neutral and deleterious polymorphism in yeast
-
Doniger, S. W. et al. A catalog of neutral and deleterious polymorphism in yeast. PLoS Genet. 4, e1000183 (2008).
-
(2008)
PLoS Genet.
, vol.4
, pp. e1000183
-
-
Doniger, S.W.1
-
15
-
-
84902511942
-
GRASP: Analysis of genotype-phenotype results from 1390 genome-wide association studies and corresponding open access database
-
Leslie, R., O'Donnell, C. J., Johnson, A. D. GRASP: analysis of genotype-phenotype results from 1390 genome-wide association studies and corresponding open access database. Bioinformatics 30, i185-i194 (2014).
-
(2014)
Bioinformatics
, vol.30
, pp. i185-i194
-
-
Leslie, R.1
O'Donnell, C.J.2
Johnson, A.D.3
-
16
-
-
29744470898
-
Germline epimutation: A basis for epigenetic disease in humans
-
Martin, D. I., Ward, R., Suter, C. M. Germline epimutation: a basis for epigenetic disease in humans. Ann. NY Acad. Sci. 1054, 68-77 (2005).
-
(2005)
Ann. NY Acad. Sci.
, vol.1054
, pp. 68-77
-
-
Martin, D.I.1
Ward, R.2
Suter, C.M.3
-
17
-
-
84923989372
-
Combined hereditary and somatic mutations of replication error repair genes result in rapid onset of ultra-hypermutated cancers
-
Shlien, A. et al. Combined hereditary and somatic mutations of replication error repair genes result in rapid onset of ultra-hypermutated cancers. Nat. Genet. 47, 257-262 (2015).
-
(2015)
Nat. Genet.
, vol.47
, pp. 257-262
-
-
Shlien, A.1
-
18
-
-
34249790004
-
Molecular mechanisms of antibody somatic hypermutation
-
Di Noia, J. M., Neuberger, M. S. Molecular mechanisms of antibody somatic hypermutation. Annu. Rev. Biochem. 76, 1-22 (2007).
-
(2007)
Annu. Rev. Biochem.
, vol.76
, pp. 1-22
-
-
Di Noia, J.M.1
Neuberger, M.S.2
-
19
-
-
81855178276
-
Somatic retrotransposition alters the genetic landscape of the human brain
-
Baillie, J. K. et al. Somatic retrotransposition alters the genetic landscape of the human brain. Nature 479, 534-537 (2011).
-
(2011)
Nature
, vol.479
, pp. 534-537
-
-
Baillie, J.K.1
-
20
-
-
77957371828
-
Mitotic recombination in patients with ichthyosis causes reversion of dominant mutations in KRT10
-
Choate, K. A. et al. Mitotic recombination in patients with ichthyosis causes reversion of dominant mutations in KRT10. Science 330, 94-97 (2010).
-
(2010)
Science
, vol.330
, pp. 94-97
-
-
Choate, K.A.1
-
21
-
-
84904464829
-
Mechanisms of natural gene therapy in dystrophic epidermolysis bullosa
-
Kiritsi, D. et al. Mechanisms of natural gene therapy in dystrophic epidermolysis bullosa. J. Invest. Dermatol. 134, 2097-2104 (2014).
-
(2014)
J. Invest. Dermatol.
, vol.134
, pp. 2097-2104
-
-
Kiritsi, D.1
-
22
-
-
0029902033
-
Spontaneous in vivo reversion to normal of an inherited mutation in a patient with adenosine deaminase deficiency
-
Hirschhorn, R. et al. Spontaneous in vivo reversion to normal of an inherited mutation in a patient with adenosine deaminase deficiency. Nat. Genet. 13, 290-295 (1996).
-
(1996)
Nat. Genet.
, vol.13
, pp. 290-295
-
-
Hirschhorn, R.1
-
23
-
-
84922758305
-
Chromothriptic cure of WHIM syndrome
-
McDermott, D. H. et al. Chromothriptic cure of WHIM syndrome. Cell 160, 686-699 (2015).
-
(2015)
Cell
, vol.160
, pp. 686-699
-
-
McDermott, D.H.1
-
24
-
-
12644293813
-
Somatic mosaicism in Fanconi anemia: Molecular basis and clinical significance
-
Lo Ten Foe, J. R. et al. Somatic mosaicism in Fanconi anemia: molecular basis and clinical significance. Eur. J. Hum. Genet. 5, 137-148 (1997).
-
(1997)
Eur. J. Hum. Genet.
, vol.5
, pp. 137-148
-
-
Lo Ten Foe, J.R.1
-
25
-
-
0032796554
-
Spontaneous functional correction of homozygous Fanconi anaemia alleles reveals novel mechanistic basis for reverse mosaicism
-
Waisfisz, Q. et al. Spontaneous functional correction of homozygous Fanconi anaemia alleles reveals novel mechanistic basis for reverse mosaicism. Nat. Genet. 22, 379-383 (1999).
-
(1999)
Nat. Genet.
, vol.22
, pp. 379-383
-
-
Waisfisz, Q.1
-
26
-
-
0034611016
-
Massive idiosyncratic exon skipping corrects the nonsense mutation in dystrophic mouse muscle and produces functional revertant fibers by clonal expansion
-
Lu, Q. L. et al. Massive idiosyncratic exon skipping corrects the nonsense mutation in dystrophic mouse muscle and produces functional revertant fibers by clonal expansion. J. Cell Biol. 148, 985-996 (2000).
-
(2000)
J. Cell Biol.
, vol.148
, pp. 985-996
-
-
Lu, Q.L.1
-
27
-
-
33645396945
-
Genetic clonal diversity predicts progression to esophageal adenocarcinoma
-
Maley, C. C. et al. Genetic clonal diversity predicts progression to esophageal adenocarcinoma. Nat. Genet. 38, 468-473 (2006).
-
(2006)
Nat. Genet.
, vol.38
, pp. 468-473
-
-
Maley, C.C.1
-
28
-
-
76649128993
-
Cellular and genetic diversity in the progression of in situ human breast carcinomas to an invasive phenotype
-
Park, S. Y., Gonen, M., Kim, H. J., Michor, F., Polyak, K. Cellular and genetic diversity in the progression of in situ human breast carcinomas to an invasive phenotype. J. Clin. Invest. 120, 636-644 (2010).
-
(2010)
J. Clin. Invest.
, vol.120
, pp. 636-644
-
-
Park, S.Y.1
Gonen, M.2
Kim, H.J.3
Michor, F.4
Polyak, K.5
-
29
-
-
84937521691
-
Somatic mosaicism: Implications for disease and transmission genetics
-
Campbell, I. M., Shaw, C. A., Stankiewicz, P., Lupski, J. R. Somatic mosaicism: implications for disease and transmission genetics. Trends Genet. 31, 382-392 (2015).
-
(2015)
Trends Genet.
, vol.31
, pp. 382-392
-
-
Campbell, I.M.1
Shaw, C.A.2
Stankiewicz, P.3
Lupski, J.R.4
-
30
-
-
84924359161
-
The reverse evolution from multicellularity to unicellularity during carcinogenesis
-
Chen, H., Lin, F., Xing, K., He, X. The reverse evolution from multicellularity to unicellularity during carcinogenesis. Nat. Commun. 6, 6367 (2015).
-
(2015)
Nat. Commun.
, vol.6
, pp. 6367
-
-
Chen, H.1
Lin, F.2
Xing, K.3
He, X.4
-
31
-
-
84945278558
-
Somatic mutation in single human neurons tracks developmental and transcriptional history
-
Lodato, M. A. et al. Somatic mutation in single human neurons tracks developmental and transcriptional history. Science 350, 94-98 (2015).
-
(2015)
Science
, vol.350
, pp. 94-98
-
-
Lodato, M.A.1
-
32
-
-
84929991442
-
Tumor evolution High burden and pervasive positive selection of somatic mutations in normal human skin
-
Martincorena, I. et al. Tumor evolution. High burden and pervasive positive selection of somatic mutations in normal human skin. Science 348, 880-886 (2015).
-
(2015)
Science
, vol.348
, pp. 880-886
-
-
Martincorena, I.1
-
33
-
-
84904861169
-
Immune surveillance of unhealthy cells by natural killer cells
-
Iannello, A., Raulet, D. H. Immune surveillance of unhealthy cells by natural killer cells. Cold Spring Harb. Symp. Quant. Biol. 78, 249-257 (2013).
-
(2013)
Cold Spring Harb. Symp. Quant. Biol.
, vol.78
, pp. 249-257
-
-
Iannello, A.1
Raulet, D.H.2
-
34
-
-
84888628269
-
Dissecting social cell biology and tumors using Drosophila genetics
-
Pastor-Pareja, J. C., Xu, T. Dissecting social cell biology and tumors using Drosophila genetics. Annu. Rev. Genet. 47, 51-74 (2013).
-
(2013)
Annu. Rev. Genet.
, vol.47
, pp. 51-74
-
-
Pastor-Pareja, J.C.1
Xu, T.2
-
35
-
-
79960940121
-
Colon stem cell and crypt dynamics exposed by cell lineage reconstruction
-
Reizel, Y. et al. Colon stem cell and crypt dynamics exposed by cell lineage reconstruction. PLoS Genet. 7, e1002192 (2011).
-
(2011)
PLoS Genet.
, vol.7
, pp. e1002192
-
-
Reizel, Y.1
-
36
-
-
77957223906
-
Intestinal crypt homeostasis results from neutral competition between symmetrically dividing Lgr5 stem cells
-
Snippert, H. J. et al. Intestinal crypt homeostasis results from neutral competition between symmetrically dividing Lgr5 stem cells. Cell 143, 134-144 (2010).
-
(2010)
Cell
, vol.143
, pp. 134-144
-
-
Snippert, H.J.1
-
38
-
-
0018188972
-
The lymphoid system. Its normal architecture and the potential for understanding the system through the study of lymphoproliferative diseases
-
Weissman, I. L., Warnke, R., Butcher, E. C., Rouse, R., Levy, R. The lymphoid system. Its normal architecture and the potential for understanding the system through the study of lymphoproliferative diseases. Hum. Pathol. 9, 25-45 (1978).
-
(1978)
Hum. Pathol.
, vol.9
, pp. 25-45
-
-
Weissman, I.L.1
Warnke, R.2
Butcher, E.C.3
Rouse, R.4
Levy, R.5
-
39
-
-
84882455458
-
Single-cell sequencing-based technologies will revolutionize whole-organism science
-
Shapiro, E., Biezuner, T., Linnarsson, S. Single-cell sequencing-based technologies will revolutionize whole-organism science. Nat. Rev. Genet. 14, 618-630 (2013).
-
(2013)
Nat. Rev. Genet.
, vol.14
, pp. 618-630
-
-
Shapiro, E.1
Biezuner, T.2
Linnarsson, S.3
-
40
-
-
84908136501
-
Clonal analysis identifies hemogenic endothelium as the source of the blood-endothelial common lineage in the mouse embryo
-
Padron-Barthe, L. et al. Clonal analysis identifies hemogenic endothelium as the source of the blood-endothelial common lineage in the mouse embryo. Blood 124, 2523-2532 (2014).
-
(2014)
Blood
, vol.124
, pp. 2523-2532
-
-
Padron-Barthe, L.1
-
41
-
-
0032750166
-
The orderly allocation of mesodermal cells to the extraembryonic structures and the anteroposterior axis during gastrulation of the mouse embryo
-
Kinder, S. J. et al. The orderly allocation of mesodermal cells to the extraembryonic structures and the anteroposterior axis during gastrulation of the mouse embryo. Development 126, 4691-4701 (1999).
-
(1999)
Development
, vol.126
, pp. 4691-4701
-
-
Kinder, S.J.1
-
42
-
-
84884365015
-
The causes and consequences of genetic heterogeneity in cancer evolution
-
Burrell, R. A., McGranahan, N., Bartek, J., Swanton, C. The causes and consequences of genetic heterogeneity in cancer evolution. Nature 501, 338-345 (2013).
-
(2013)
Nature
, vol.501
, pp. 338-345
-
-
Burrell, R.A.1
McGranahan, N.2
Bartek, J.3
Swanton, C.4
-
43
-
-
84904332749
-
Darwin's multicellularity: From neurotrophic theories and cell competition to fitness fingerprints
-
Moreno, E., Rhiner, C. Darwin's multicellularity: from neurotrophic theories and cell competition to fitness fingerprints. Curr. Opin. Cell Biol. 31, 16-22 (2014).
-
(2014)
Curr. Opin. Cell Biol.
, vol.31
, pp. 16-22
-
-
Moreno, E.1
Rhiner, C.2
-
44
-
-
84856241444
-
Interface between normal and transformed epithelial cells: A road to a novel type of cancer prevention and treatment
-
Fujita, Y. Interface between normal and transformed epithelial cells: a road to a novel type of cancer prevention and treatment. Cancer Sci. 102, 1749-1755 (2011).
-
(2011)
Cancer Sci.
, vol.102
, pp. 1749-1755
-
-
Fujita, Y.1
-
45
-
-
84938850603
-
Paracrine signaling between tumor subclones of mouse SCLC: A critical role of ETS transcription factor Pea3 in facilitating metastasis
-
Kwon, M. C. et al. Paracrine signaling between tumor subclones of mouse SCLC: a critical role of ETS transcription factor Pea3 in facilitating metastasis. Genes Dev. 29, 1587-1592 (2015).
-
(2015)
Genes Dev.
, vol.29
, pp. 1587-1592
-
-
Kwon, M.C.1
-
46
-
-
84901246854
-
Cell competition is a tumour suppressor mechanism in the thymus
-
Martins, V. C. et al. Cell competition is a tumour suppressor mechanism in the thymus. Nature 509, 465-470 (2014).
-
(2014)
Nature
, vol.509
, pp. 465-470
-
-
Martins, V.C.1
-
47
-
-
79959947008
-
Biomechanical remodeling of the microenvironment by stromal caveolin-1 favors tumor invasion and metastasis
-
Goetz, J. G. et al. Biomechanical remodeling of the microenvironment by stromal caveolin-1 favors tumor invasion and metastasis. Cell 146, 148-163 (2011).
-
(2011)
Cell
, vol.146
, pp. 148-163
-
-
Goetz, J.G.1
-
48
-
-
84876592083
-
A genomic view of mosaicism and human disease
-
Biesecker, L. G., Spinner, N. B. A genomic view of mosaicism and human disease. Nat. Rev. Genet. 14, 307-320 (2013).
-
(2013)
Nat. Rev. Genet.
, vol.14
, pp. 307-320
-
-
Biesecker, L.G.1
Spinner, N.B.2
-
49
-
-
0027276927
-
In utero rearrangements in the trithorax-related oncogene in infant leukaemias
-
Ford, A. M. et al. In utero rearrangements in the trithorax-related oncogene in infant leukaemias. Nature 363, 358-360 (1993).
-
(1993)
Nature
, vol.363
, pp. 358-360
-
-
Ford, A.M.1
-
50
-
-
0033619452
-
Prenatal origin of acute lymphoblastic leukaemia in children
-
Wiemels, J. L. et al. Prenatal origin of acute lymphoblastic leukaemia in children. Lancet 354, 1499-1503 (1999).
-
(1999)
Lancet
, vol.354
, pp. 1499-1503
-
-
Wiemels, J.L.1
-
51
-
-
6344285984
-
Prenatal origin of separate evolution of leukemia in identical twins
-
Teuffel, O. et al. Prenatal origin of separate evolution of leukemia in identical twins. Leukemia 18, 1624-1629 (2004).
-
(2004)
Leukemia
, vol.18
, pp. 1624-1629
-
-
Teuffel, O.1
-
52
-
-
77949448846
-
Darwin and evolutionary tales in leukemia. The Ham-Wasserman Lecture
-
Greaves, M. Darwin and evolutionary tales in leukemia. The Ham-Wasserman Lecture. Hematology Am. Soc. Hematol. Educ. Program 2009, 3-12 (2009).
-
(2009)
Hematology Am. Soc. Hematol. Educ. Program
, vol.2009
, pp. 3-12
-
-
Greaves, M.1
-
53
-
-
0344838398
-
Prenatal origin of TEL-AML1-positive acute lymphoblastic leukemia in children born in California
-
McHale, C. M. et al. Prenatal origin of TEL-AML1-positive acute lymphoblastic leukemia in children born in California. Genes Chromosomes Cancer 37, 36-43 (2003).
-
(2003)
Genes Chromosomes Cancer
, vol.37
, pp. 36-43
-
-
McHale, C.M.1
-
54
-
-
0037062496
-
Chromosome translocations and covert leukemic clones are generated during normal fetal development
-
Mori, H. et al. Chromosome translocations and covert leukemic clones are generated during normal fetal development. Proc. Natl Acad. Sci. USA 99, 8242-8247 (2002).
-
(2002)
Proc. Natl Acad. Sci. USA
, vol.99
, pp. 8242-8247
-
-
Mori, H.1
-
55
-
-
0029045087
-
The t(12;21) of acute lymphoblastic leukemia results in a telAML1 gene fusion
-
Romana, S. P. et al. The t(12;21) of acute lymphoblastic leukemia results in a telAML1 gene fusion. Blood 85, 3662-3670 (1995).
-
(1995)
Blood
, vol.85
, pp. 3662-3670
-
-
Romana, S.P.1
-
56
-
-
13344282725
-
TEL/AML1 fusion resulting from a cryptic t(12;21) is the most common genetic lesion in pediatric ALL and defines a subgroup of patients with an excellent prognosis
-
Shurtleff, S. A. et al. TEL/AML1 fusion resulting from a cryptic t(12;21) is the most common genetic lesion in pediatric ALL and defines a subgroup of patients with an excellent prognosis. Leukemia. 9, 1985-1989 (1995).
-
(1995)
Leukemia
, vol.9
, pp. 1985-1989
-
-
Shurtleff, S.A.1
-
57
-
-
0030742017
-
Incidence and clinical relevance of TEL/AML1 fusion genes in children with acute lymphoblastic leukemia enrolled in the German and Italian multicenter therapy trials
-
Borkhardt, A. et al. Incidence and clinical relevance of TEL/AML1 fusion genes in children with acute lymphoblastic leukemia enrolled in the German and Italian multicenter therapy trials. Blood 90, 571-577 (1997).
-
(1997)
Blood
, vol.90
, pp. 571-577
-
-
Borkhardt, A.1
-
58
-
-
38349183668
-
Initiating and cancer-propagating cells in TELAML1associated childhood leukemia
-
Hong, D. et al. Initiating and cancer-propagating cells in TELAML1associated childhood leukemia. Science 319, 336-339 (2008).
-
(2008)
Science
, vol.319
, pp. 336-339
-
-
Hong, D.1
-
59
-
-
84874303729
-
TEL (ETV6)-AML1 (RUNX1) initiates self-renewing fetal proB cells in association with a transcriptional program shared with embryonic stem cells in mice
-
Tsuzuki, S., Seto, M. TEL (ETV6)-AML1 (RUNX1) initiates self-renewing fetal proB cells in association with a transcriptional program shared with embryonic stem cells in mice. Stem Cells 31, 236-247 (2013).
-
(2013)
Stem Cells
, vol.31
, pp. 236-247
-
-
Tsuzuki, S.1
Seto, M.2
-
60
-
-
0035254207
-
Breakage and fusion of the TEL (ETV6) gene in immature B lymphocytes induced by apoptogenic signals
-
Eguchi-Ishimae, M. et al. Breakage and fusion of the TEL (ETV6) gene in immature B lymphocytes induced by apoptogenic signals. Blood 97, 737-743 (2001).
-
(2001)
Blood
, vol.97
, pp. 737-743
-
-
Eguchi-Ishimae, M.1
-
61
-
-
84897440556
-
The prenatal origins of cancer
-
Marshall, G. M. et al. The prenatal origins of cancer. Nat. Rev. Cancer 14, 277-289 (2014).
-
(2014)
Nat. Rev. Cancer
, vol.14
, pp. 277-289
-
-
Marshall, G.M.1
-
62
-
-
0037100422
-
Immature CD34+CD19-progenitor/stem cells in TEL/AML1positive acute lymphoblastic leukemia are genetically and functionally normal
-
Hotfilder, M. et al. Immature CD34+CD19-progenitor/stem cells in TEL/AML1positive acute lymphoblastic leukemia are genetically and functionally normal. Blood 100, 640-646 (2002).
-
(2002)
Blood
, vol.100
, pp. 640-646
-
-
Hotfilder, M.1
-
63
-
-
0141634051
-
Origins of chromosome translocations in childhood leukaemia
-
Greaves, M. F., Wiemels, J. Origins of chromosome translocations in childhood leukaemia. Nat. Rev. Cancer 3, 639-649 (2003).
-
(2003)
Nat. Rev. Cancer
, vol.3
, pp. 639-649
-
-
Greaves, M.F.1
Wiemels, J.2
-
64
-
-
0031471132
-
Backtracking leukemia to birth: Identification of clonotypic gene fusion sequences in neonatal blood spots
-
Gale, K. B. et al. Backtracking leukemia to birth: identification of clonotypic gene fusion sequences in neonatal blood spots. Proc. Natl Acad. Sci. USA 94, 13950-13954 (1997).
-
(1997)
Proc. Natl Acad. Sci. USA
, vol.94
, pp. 13950-13954
-
-
Gale, K.B.1
-
65
-
-
81555205127
-
Developmental origins and impact of BCRABL1 fusion and IKZF1 deletions in monozygotic twins with Ph+ acute lymphoblastic leukemia
-
Cazzaniga, G. et al. Developmental origins and impact of BCRABL1 fusion and IKZF1 deletions in monozygotic twins with Ph+ acute lymphoblastic leukemia. Blood 118, 5559-5564 (2011).
-
(2011)
Blood
, vol.118
, pp. 5559-5564
-
-
Cazzaniga, G.1
-
66
-
-
84865155361
-
Somatic mosaicism for oncogenic NRAS mutations in juvenile myelomonocytic leukemia
-
Doisaki, S. et al. Somatic mosaicism for oncogenic NRAS mutations in juvenile myelomonocytic leukemia. Blood 120, 1485-1488 (2012).
-
(2012)
Blood
, vol.120
, pp. 1485-1488
-
-
Doisaki, S.1
-
68
-
-
0023319298
-
Lethal genes surviving by mosaicism: A possible explanation for sporadic birth defects involving the skin
-
Happle, R. Lethal genes surviving by mosaicism: a possible explanation for sporadic birth defects involving the skin. J. Am. Acad. Dermatol. 16, 899-906 (1987).
-
(1987)
J. Am. Acad. Dermatol.
, vol.16
, pp. 899-906
-
-
Happle, R.1
-
69
-
-
33746754183
-
Mosaicism of activating FGFR3 mutations in human skin causes epidermal nevi
-
Hafner, C. et al. Mosaicism of activating FGFR3 mutations in human skin causes epidermal nevi. J. Clin. Invest. 116, 2201-2207 (2006).
-
(2006)
J. Clin. Invest.
, vol.116
, pp. 2201-2207
-
-
Hafner, C.1
-
70
-
-
34548069945
-
Oncogenic PIK3CA mutations occur in epidermal nevi and seborrheic keratoses with a characteristic mutation pattern
-
Hafner, C. et al. Oncogenic PIK3CA mutations occur in epidermal nevi and seborrheic keratoses with a characteristic mutation pattern. Proc. Natl Acad. Sci. USA 104, 13450-13454 (2007).
-
(2007)
Proc. Natl Acad. Sci. USA
, vol.104
, pp. 13450-13454
-
-
Hafner, C.1
-
71
-
-
84864078171
-
Keratinocytic epidermal nevi are associated with mosaic RAS mutations
-
Hafner, C. et al. Keratinocytic epidermal nevi are associated with mosaic RAS mutations. J. Med. Genet. 49, 249-253 (2012).
-
(2012)
J. Med. Genet.
, vol.49
, pp. 249-253
-
-
Hafner, C.1
-
72
-
-
78649620521
-
Mosaicism for oncogenic G12D KRAS mutation associated with epidermal nevus, polycystic kidneys and rhabdomyosarcoma
-
Bourdeaut, F. et al. Mosaicism for oncogenic G12D KRAS mutation associated with epidermal nevus, polycystic kidneys and rhabdomyosarcoma. J. Med. Genet. 47, 859-862 (2010).
-
(2010)
J. Med. Genet.
, vol.47
, pp. 859-862
-
-
Bourdeaut, F.1
-
73
-
-
81455135721
-
HRAS mutation mosaicism causing urothelial cancer and epidermal nevus
-
Hafner, C., Toll, A., Real, F. X. HRAS mutation mosaicism causing urothelial cancer and epidermal nevus. N. Engl. J. Med. 365, 1940-1942 (2011).
-
(2011)
N. Engl. J. Med.
, vol.365
, pp. 1940-1942
-
-
Hafner, C.1
Toll, A.2
Real, F.X.3
-
74
-
-
50849096110
-
Somatic oncogenic mutations benign skin lesions and cancer progression: Where to look next
-
Toll, A., Real, F. X. Somatic oncogenic mutations, benign skin lesions and cancer progression: where to look next Cell Cycle 7, 2674-2681 (2008).
-
(2008)
Cell Cycle
, vol.7
, pp. 2674-2681
-
-
Toll, A.1
Real, F.X.2
-
75
-
-
84862982298
-
Postzygotic HRAS and KRAS mutations cause nevus sebaceous and Schimmelpenning syndrome
-
Groesser, L. et al. Postzygotic HRAS and KRAS mutations cause nevus sebaceous and Schimmelpenning syndrome. Nat. Genet. 44, 783-787 (2012).
-
(2012)
Nat. Genet.
, vol.44
, pp. 783-787
-
-
Groesser, L.1
-
76
-
-
84856227825
-
Nevus sebaceous revisited
-
Moody, M. N., Landau, J. M., Goldberg, L. H. Nevus sebaceous revisited. Pediatr. Dermatol. 29, 15-23 (2012).
-
(2012)
Pediatr. Dermatol.
, vol.29
, pp. 15-23
-
-
Moody, M.N.1
Landau, J.M.2
Goldberg, L.H.3
-
77
-
-
84880324718
-
Phacomatosis pigmentokeratotica is caused by a postzygotic HRAS mutation in a multipotent progenitor cell
-
Groesser, L. et al. Phacomatosis pigmentokeratotica is caused by a postzygotic HRAS mutation in a multipotent progenitor cell. J. Invest. Dermatol. 133, 1998-2003 (2013).
-
(2013)
J. Invest. Dermatol.
, vol.133
, pp. 1998-2003
-
-
Groesser, L.1
-
78
-
-
84873902078
-
Birthmarks of medical significance in the neonate
-
Benjamin, L. T. Birthmarks of medical significance in the neonate. Semin. Perinatol. 37, 16-19 (2013).
-
(2013)
Semin. Perinatol.
, vol.37
, pp. 16-19
-
-
Benjamin, L.T.1
-
79
-
-
84884365535
-
Making a mountain out of a molehill: NRAS, mosaicism, and large congenital nevi
-
Gerami, P., Paller, A. S. Making a mountain out of a molehill: NRAS, mosaicism, and large congenital nevi. J. Invest. Dermatol. 133, 2127-2130 (2013).
-
(2013)
J. Invest. Dermatol.
, vol.133
, pp. 2127-2130
-
-
Gerami, P.1
Paller, A.S.2
-
80
-
-
33746819361
-
High frequency of BRAFV600E mutation in acquired nevi and small congenital nevi, but low frequency of mutation in medium-sized congenital nevi
-
Ichii-Nakato, N. et al. High frequency of BRAFV600E mutation in acquired nevi and small congenital nevi, but low frequency of mutation in medium-sized congenital nevi. J. Invest. Dermatol. 126, 2111-2118 (2006).
-
(2006)
J. Invest. Dermatol.
, vol.126
, pp. 2111-2118
-
-
Ichii-Nakato, N.1
-
81
-
-
84884412000
-
Multiple congenital melanocytic nevi and neurocutaneous melanosis are caused by postzygotic mutations in codon 61 of NRAS
-
Kinsler, V. A. et al. Multiple congenital melanocytic nevi and neurocutaneous melanosis are caused by postzygotic mutations in codon 61 of NRAS. J. Invest. Dermatol. 133, 2229-2236 (2013).
-
(2013)
J. Invest. Dermatol.
, vol.133
, pp. 2229-2236
-
-
Kinsler, V.A.1
-
82
-
-
33749485297
-
Somatic mosaicism for an HRAS mutation causes Costello syndrome
-
Gripp, K. W., Stabley, D. L., Nicholson, L., Hoffman, J. D., Sol-Church, K. Somatic mosaicism for an HRAS mutation causes Costello syndrome. Am. J. Med. Genet. A 140, 2163-2169 (2006).
-
(2006)
Am. J. Med. Genet. A
, vol.140
, pp. 2163-2169
-
-
Gripp, K.W.1
Stabley, D.L.2
Nicholson, L.3
Hoffman, J.D.4
Sol-Church, K.5
-
83
-
-
84860389181
-
A mosaic activating mutation in AKT1 associated with the Proteus syndrome
-
Lindhurst, M. J. et al. A mosaic activating mutation in AKT1 associated with the Proteus syndrome. N. Engl. J. Med. 365, 611-619 (2011).
-
(2011)
N. Engl. J. Med.
, vol.365
, pp. 611-619
-
-
Lindhurst, M.J.1
-
84
-
-
84862129718
-
Somatic mosaic activating mutations in PIK3CA cause CLOVES syndrome
-
Kurek, K. C. et al. Somatic mosaic activating mutations in PIK3CA cause CLOVES syndrome. Am. J. Hum. Genet. 90, 1108-1115 (2012).
-
(2012)
Am. J. Hum. Genet.
, vol.90
, pp. 1108-1115
-
-
Kurek, K.C.1
-
85
-
-
84877957142
-
Sturge-Weber syndrome and portwine stains caused by somatic mutation in GNAQ
-
Shirley, M. D. et al. Sturge-Weber syndrome and portwine stains caused by somatic mutation in GNAQ. N. Engl. J. Med. 368, 1971-1979 (2013).
-
(2013)
N. Engl. J. Med.
, vol.368
, pp. 1971-1979
-
-
Shirley, M.D.1
-
86
-
-
0030070963
-
Somatic mosaicism in a patient with neurofibromatosis type 1
-
Colman, S. D., Rasmussen, S. A., Ho, V. T., Abernathy, C. R., Wallace, M. R. Somatic mosaicism in a patient with neurofibromatosis type 1. Am. J. Hum. Genet. 58, 484-490 (1996).
-
(1996)
Am. J. Hum. Genet.
, vol.58
, pp. 484-490
-
-
Colman, S.D.1
Rasmussen, S.A.2
Ho, V.T.3
Abernathy, C.R.4
Wallace, M.R.5
-
87
-
-
79551573541
-
Mosaic type1 NF1 microdeletions as a cause of both generalized and segmental neurofibromatosis type1 (NF1)
-
Messiaen, L. et al. Mosaic type1 NF1 microdeletions as a cause of both generalized and segmental neurofibromatosis type1 (NF1). Hum. Mutat. 32, 213-219 (2011).
-
(2011)
Hum. Mutat.
, vol.32
, pp. 213-219
-
-
Messiaen, L.1
-
88
-
-
0027405720
-
A novel moesin-, ezrin-, radixinlike gene is a candidate for the neurofibromatosis 2 tumor suppressor
-
Trofatter, J. A. et al. A novel moesin-, ezrin-, radixinlike gene is a candidate for the neurofibromatosis 2 tumor suppressor. Cell 72, 791-800 (1993).
-
(1993)
Cell
, vol.72
, pp. 791-800
-
-
Trofatter, J.A.1
-
89
-
-
3242661620
-
Genotype-phenotype correlations for nervous system tumors in neurofibromatosis 2: A population-based study
-
Baser, M. E. et al. Genotype-phenotype correlations for nervous system tumors in neurofibromatosis 2: a population-based study. Am. J. Hum. Genet. 75, 231-239 (2004).
-
(2004)
Am. J. Hum. Genet.
, vol.75
, pp. 231-239
-
-
Baser, M.E.1
-
90
-
-
77957564914
-
Meningiomas and neurofibromatosis
-
Goutagny, S., Kalamarides, M. Meningiomas and neurofibromatosis. J. Neurooncol. 99, 341-347 (2010).
-
(2010)
J. Neurooncol.
, vol.99
, pp. 341-347
-
-
Goutagny, S.1
Kalamarides, M.2
-
91
-
-
82255183051
-
Ollier disease and Maffucci syndrome are caused by somatic mosaic mutations of IDH1 and IDH2
-
Amary, M. F. et al. Ollier disease and Maffucci syndrome are caused by somatic mosaic mutations of IDH1 and IDH2. Nat. Genet. 43, 1262-1265 (2011).
-
(2011)
Nat. Genet.
, vol.43
, pp. 1262-1265
-
-
Amary, M.F.1
-
92
-
-
82255183048
-
Somatic mosaic IDH1 and IDH2 mutations are associated with enchondroma and spindle cell hemangioma in Ollier disease and Maffucci syndrome
-
Pansuriya, T. C. et al. Somatic mosaic IDH1 and IDH2 mutations are associated with enchondroma and spindle cell hemangioma in Ollier disease and Maffucci syndrome. Nat. Genet. 43, 1256-1261 (2011).
-
(2011)
Nat. Genet.
, vol.43
, pp. 1256-1261
-
-
Pansuriya, T.C.1
-
93
-
-
84901272540
-
RB1 mutation spectrum in a comprehensive nationwide cohort of retinoblastoma patients
-
Dommering, C. J. et al. RB1 mutation spectrum in a comprehensive nationwide cohort of retinoblastoma patients. J. Med. Genet. 51, 366-374 (2014).
-
(2014)
J. Med. Genet.
, vol.51
, pp. 366-374
-
-
Dommering, C.J.1
-
94
-
-
84944353204
-
Next generation sequencing in sporadic retinoblastoma patients reveals somatic mosaicism
-
Amitrano, S. et al. Next generation sequencing in sporadic retinoblastoma patients reveals somatic mosaicism. Eur. J. Hum. Genet. 23, 1523-1530 (2015).
-
(2015)
Eur. J. Hum. Genet.
, vol.23
, pp. 1523-1530
-
-
Amitrano, S.1
-
95
-
-
81055126264
-
Mutations in 12 genes for inherited ovarian, fallopian tube, and peritoneal carcinoma identified by massively parallel sequencing
-
Walsh, T. et al. Mutations in 12 genes for inherited ovarian, fallopian tube, and peritoneal carcinoma identified by massively parallel sequencing. Proc. Natl Acad. Sci. USA 108, 18032-18037 (2011).
-
(2011)
Proc. Natl Acad. Sci. USA
, vol.108
, pp. 18032-18037
-
-
Walsh, T.1
-
96
-
-
84927176106
-
A pathogenic mosaic TP53 mutation in two germ layers detected by next generation sequencing
-
Behjati, S. et al. A pathogenic mosaic TP53 mutation in two germ layers detected by next generation sequencing. PLoS ONE 9, e96531 (2014).
-
(2014)
PLoS ONE
, vol.9
, pp. e96531
-
-
Behjati, S.1
-
97
-
-
38349147316
-
Somatic APC mosaicism: An underestimated cause of polyposis coli
-
Hes, F. J. et al. Somatic APC mosaicism: an underestimated cause of polyposis coli. Gut 57, 71-76 (2008).
-
(2008)
Gut
, vol.57
, pp. 71-76
-
-
Hes, F.J.1
-
98
-
-
65349097927
-
Familial adenomatous polyposis
-
Macrae, F., du Sart, D., Nasioulas, S. Familial adenomatous polyposis. Best Pract. Res. Clin. Gastroenterol. 23, 197-207 (2009).
-
(2009)
Best Pract. Res. Clin. Gastroenterol.
, vol.23
, pp. 197-207
-
-
MacRae, F.1
Du Sart, D.2
Nasioulas, S.3
-
99
-
-
79961126727
-
Detection of APC germ line mosaicism in patients with de novo familial adenomatous polyposis: A plea for the protein truncation test
-
Necker, J., Kovac, M., Attenhofer, M., Reichlin, B., Heinimann, K. Detection of APC germ line mosaicism in patients with de novo familial adenomatous polyposis: a plea for the protein truncation test. J. Med. Genet. 48, 526-529 (2011).
-
(2011)
J. Med. Genet.
, vol.48
, pp. 526-529
-
-
Necker, J.1
Kovac, M.2
Attenhofer, M.3
Reichlin, B.4
Heinimann, K.5
-
100
-
-
84923610613
-
Low-level constitutional mosaicism of a de novo BRCA1 gene mutation
-
Friedman, E. et al. Low-level constitutional mosaicism of a de novo BRCA1 gene mutation. Br. J. Cancer. 112, 765-768 (2015).
-
(2015)
Br. J. Cancer.
, vol.112
, pp. 765-768
-
-
Friedman, E.1
-
101
-
-
84872621246
-
Mosaic PPM1D mutations are associated with predisposition to breast and ovarian cancer
-
Ruark, E. et al. Mosaic PPM1D mutations are associated with predisposition to breast and ovarian cancer. Nature 493, 406-410 (2013).
-
(2013)
Nature
, vol.493
, pp. 406-410
-
-
Ruark, E.1
-
102
-
-
84892631703
-
PPM1D mutations in circulating white blood cells and the risk for ovarian cancer
-
Akbari, M. R. et al. PPM1D mutations in circulating white blood cells and the risk for ovarian cancer. J. Natl Cancer Inst. 106, 323 (2014).
-
(2014)
J. Natl Cancer Inst.
, vol.106
, pp. 323
-
-
Akbari, M.R.1
-
103
-
-
84893813840
-
Mosaicism in HIF2Arelated polycythemia-paraganglioma syndrome
-
Buffet, A. et al. Mosaicism in HIF2Arelated polycythemia-paraganglioma syndrome. J. Clin. Endocrinol. Metab. 99, E369-E373 (2014).
-
(2014)
J. Clin. Endocrinol. Metab.
, vol.99
, pp. E369-E373
-
-
Buffet, A.1
-
104
-
-
77955066602
-
Mosaic uniparental disomies and aneuploidies as large structural variants of the human genome
-
Rodriguez-Santiago, B. et al. Mosaic uniparental disomies and aneuploidies as large structural variants of the human genome. Am. J. Hum. Genet. 87, 129-138 (2010).
-
(2010)
Am. J. Hum. Genet.
, vol.87
, pp. 129-138
-
-
Rodriguez-Santiago, B.1
-
105
-
-
84921288028
-
Cancer etiology. Variation in cancer risk among tissues can be explained by the number of stem cell divisions
-
Tomasetti, C., Vogelstein, B. Cancer etiology. Variation in cancer risk among tissues can be explained by the number of stem cell divisions. Science 347, 78-81 (2015).
-
(2015)
Science
, vol.347
, pp. 78-81
-
-
Tomasetti, C.1
Vogelstein, B.2
-
106
-
-
84941795693
-
A critical examination of the bad luck" explanation of cancer risk
-
Rozhok, A. I., Wahl, G. M., DeGregori, J. A critical examination of the "bad luck" explanation of cancer risk. Cancer Prev. Res. (Phila.) 8, 762-764 (2015).
-
(2015)
Cancer Prev. Res. (Phila.)
, vol.8
, pp. 762-764
-
-
Rozhok, A.I.1
Wahl, G.M.2
DeGregori, J.3
-
107
-
-
0023275274
-
Molecular analysis of the t(14;18) chromosomal translocation in malignant lymphomas
-
Weiss, L. M., Warnke, R. A., Sklar, J., Cleary, M. L. Molecular analysis of the t(14;18) chromosomal translocation in malignant lymphomas. N. Engl. J. Med. 317, 1185-1189 (1987).
-
(1987)
N. Engl. J. Med.
, vol.317
, pp. 1185-1189
-
-
Weiss, L.M.1
Warnke, R.A.2
Sklar, J.3
Cleary, M.L.4
-
108
-
-
0025989443
-
Enhanced detection of the t(14;18) translocation in malignant lymphoma using pulsed-field gel electrophoresis
-
Zelenetz, A. D. et al. Enhanced detection of the t(14;18) translocation in malignant lymphoma using pulsed-field gel electrophoresis. Blood 78, 1552-1560 (1991).
-
(1991)
Blood
, vol.78
, pp. 1552-1560
-
-
Zelenetz, A.D.1
-
109
-
-
0024521441
-
Bcl2Immunoglobulin transgenic mice demonstrate extended B cell survival and follicular lymphoproliferation
-
McDonnell, T. J. et al. bcl2Immunoglobulin transgenic mice demonstrate extended B cell survival and follicular lymphoproliferation. Cell 57, 79-88 (1989).
-
(1989)
Cell
, vol.57
, pp. 79-88
-
-
McDonnell, T.J.1
-
110
-
-
1542283724
-
VavPBcl2 transgenic mice develop follicular lymphoma preceded by germinal center hyperplasia
-
Egle, A., Harris, A. W., Bath, M. L., O'Reilly, L., Cory, S. VavPBcl2 transgenic mice develop follicular lymphoma preceded by germinal center hyperplasia. Blood 103, 2276-2283 (2004).
-
(2004)
Blood
, vol.103
, pp. 2276-2283
-
-
Egle, A.1
Harris, A.W.2
Bath, M.L.3
O'Reilly, L.4
Cory, S.5
-
111
-
-
33644990397
-
Long-term clonal persistence and evolution of t(14;18)-bearing B cells in healthy individuals
-
Roulland, S. et al. Long-term clonal persistence and evolution of t(14;18)-bearing B cells in healthy individuals. Leukemia 20, 158-162 (2006).
-
(2006)
Leukemia
, vol.20
, pp. 158-162
-
-
Roulland, S.1
-
112
-
-
84902684758
-
T(14;18) translocation: A predictive blood biomarker for follicular lymphoma
-
Roulland, S. et al. t(14;18) translocation: a predictive blood biomarker for follicular lymphoma. J. Clin. Oncol. 32, 1347-1355 (2014).
-
(2014)
J. Clin. Oncol.
, vol.32
, pp. 1347-1355
-
-
Roulland, S.1
-
113
-
-
84920955541
-
Molecular pathogenesis of follicular lymphoma
-
Kishimoto, W., Nishikori, M. Molecular pathogenesis of follicular lymphoma. J. Clin. Exp. Hematop. 54, 23-30 (2014).
-
(2014)
J. Clin. Exp. Hematop.
, vol.54
, pp. 23-30
-
-
Kishimoto, W.1
Nishikori, M.2
-
114
-
-
84857050624
-
Age-related somatic structural changes in the nuclear genome of human blood cells
-
Forsberg, L. A. et al. Age-related somatic structural changes in the nuclear genome of human blood cells. Am. J. Hum. Genet. 90, 217-228 (2012).
-
(2012)
Am. J. Hum. Genet.
, vol.90
, pp. 217-228
-
-
Forsberg, L.A.1
-
115
-
-
84861628224
-
Detectable clonal mosaicism and its relationship to aging and cancer
-
Jacobs, K. B. et al. Detectable clonal mosaicism and its relationship to aging and cancer. Nat. Genet. 44, 651-658 (2012).
-
(2012)
Nat. Genet.
, vol.44
, pp. 651-658
-
-
Jacobs, K.B.1
-
116
-
-
84861591789
-
Detectable clonal mosaicism from birth to old age and its relationship to cancer
-
Laurie, C. C. et al. Detectable clonal mosaicism from birth to old age and its relationship to cancer. Nat. Genet. 44, 642-650 (2012).
-
(2012)
Nat. Genet.
, vol.44
, pp. 642-650
-
-
Laurie, C.C.1
-
117
-
-
84924140975
-
Characterization of large structural genetic mosaicism in human autosomes
-
Machiela, M. J. et al. Characterization of large structural genetic mosaicism in human autosomes. Am. J. Hum. Genet. 96, 487-497 (2015).
-
(2015)
Am. J. Hum. Genet.
, vol.96
, pp. 487-497
-
-
MacHiela, M.J.1
-
118
-
-
84856246409
-
Structural genetic variation in the context of somatic mosaicism
-
Dumanski, J. P., Piotrowski, A. Structural genetic variation in the context of somatic mosaicism. Methods Mol. Biol. 838, 249-272 (2012).
-
(2012)
Methods Mol. Biol.
, vol.838
, pp. 249-272
-
-
Dumanski, J.P.1
Piotrowski, A.2
-
119
-
-
84883464230
-
Association between large detectable clonal mosaicism and type 2 diabetes with vascular complications
-
Bonnefond, A. et al. Association between large detectable clonal mosaicism and type 2 diabetes with vascular complications. Nat. Genet. 45, 1040-1043 (2013).
-
(2013)
Nat. Genet.
, vol.45
, pp. 1040-1043
-
-
Bonnefond, A.1
-
120
-
-
84924620531
-
Leukemia-associated somatic mutations drive distinct patterns of age-related clonal hemopoiesis
-
McKerrell, T. et al. Leukemia-associated somatic mutations drive distinct patterns of age-related clonal hemopoiesis. Cell Rep. 10, 1239-1245 (2015).
-
(2015)
Cell Rep.
, vol.10
, pp. 1239-1245
-
-
McKerrell, T.1
-
121
-
-
84875312416
-
Confirmation of the reported association of clonal chromosomal mosaicism with an increased risk of incident hematologic cancer
-
Schick, U. M. et al. Confirmation of the reported association of clonal chromosomal mosaicism with an increased risk of incident hematologic cancer. PLoS ONE 8, e59823 (2013).
-
(2013)
PLoS ONE
, vol.8
, pp. e59823
-
-
Schick, U.M.1
-
122
-
-
84924691959
-
Clonal hematopoiesis and bloodcancer risk
-
Genovese, G., Jaiswal, S., Ebert, B. L., McCarroll, S. A. Clonal hematopoiesis and bloodcancer risk. N. Engl. J. Med. 372, 1071-1072 (2015).
-
(2015)
N. Engl. J. Med.
, vol.372
, pp. 1071-1072
-
-
Genovese, G.1
Jaiswal, S.2
Ebert, B.L.3
McCarroll, S.A.4
-
123
-
-
84920053873
-
Age-related clonal hematopoiesis associated with adverse outcomes
-
Jaiswal, S. et al. Age-related clonal hematopoiesis associated with adverse outcomes. N. Engl. J. Med. 371, 2488-2498 (2014).
-
(2014)
N. Engl. J. Med.
, vol.371
, pp. 2488-2498
-
-
Jaiswal, S.1
-
124
-
-
84922693801
-
Effect of mutation order on myeloproliferative neoplasms
-
Ortmann, C. A. et al. Effect of mutation order on myeloproliferative neoplasms. N. Engl. J. Med. 372, 601-612 (2015).
-
(2015)
N. Engl. J. Med.
, vol.372
, pp. 601-612
-
-
Ortmann, C.A.1
-
126
-
-
10644258336
-
Constitutional aneuploidy and cancer predisposition caused by biallelic mutations in BUB1B
-
Hanks, S. et al. Constitutional aneuploidy and cancer predisposition caused by biallelic mutations in BUB1B. Nat. Genet. 36, 1159-1161 (2004).
-
(2004)
Nat. Genet.
, vol.36
, pp. 1159-1161
-
-
Hanks, S.1
-
127
-
-
79957612407
-
Mutations in CEP57 cause mosaic variegated aneuploidy syndrome
-
Snape, K. et al. Mutations in CEP57 cause mosaic variegated aneuploidy syndrome. Nat. Genet. 43, 527-529 (2011).
-
(2011)
Nat. Genet.
, vol.43
, pp. 527-529
-
-
Snape, K.1
-
128
-
-
84901682843
-
Mosaic loss of chromosome y in peripheral blood is associated with shorter survival and higher risk of cancer
-
Forsberg, L. A. et al. Mosaic loss of chromosome Y in peripheral blood is associated with shorter survival and higher risk of cancer. Nat. Genet. 46, 624-628 (2014).
-
(2014)
Nat. Genet.
, vol.46
, pp. 624-628
-
-
Forsberg, L.A.1
-
129
-
-
84922481318
-
Mutagenesis. Smoking is associated with mosaic loss of chromosome y
-
Dumanski, J. P. et al. Mutagenesis. Smoking is associated with mosaic loss of chromosome Y. Science 347, 81-83 (2015).
-
(2015)
Science
, vol.347
, pp. 81-83
-
-
Dumanski, J.P.1
-
130
-
-
78650582977
-
Multiple oncogenic mutations and clonal relationship in spatially distinct benign human epidermal tumors
-
Hafner, C. et al. Multiple oncogenic mutations and clonal relationship in spatially distinct benign human epidermal tumors. Proc. Natl Acad. Sci. USA 107, 20780-20785 (2010).
-
(2010)
Proc. Natl Acad. Sci. USA
, vol.107
, pp. 20780-20785
-
-
Hafner, C.1
-
131
-
-
78651056338
-
Field cancerization in oral stratified squamous epithelium; Clinical implications of multicentric origin
-
Slaughter, D. P., Southwick, H. W., Smejkal, W. Field cancerization in oral stratified squamous epithelium; clinical implications of multicentric origin. Cancer 6, 963-968 (1953).
-
(1953)
Cancer
, vol.6
, pp. 963-968
-
-
Slaughter, D.P.1
Southwick, H.W.2
Smejkal, W.3
-
132
-
-
84931575394
-
Cancer stem cells and field cancerization of oral squamous cell carcinoma
-
Simple, M., Suresh, A., Das, D., Kuriakose, M. A. Cancer stem cells and field cancerization of oral squamous cell carcinoma. Oral Oncol. 51, 643-651 (2015).
-
(2015)
Oral Oncol.
, vol.51
, pp. 643-651
-
-
Simple, M.1
Suresh, A.2
Das, D.3
Kuriakose, M.A.4
-
133
-
-
84903822477
-
Oral field cancerization: An update on current concepts
-
Mohan, M., Jagannathan, N. Oral field cancerization: an update on current concepts. Oncol. Rev. 8, 244 (2014).
-
(2014)
Oncol. Rev.
, vol.8
, pp. 244
-
-
Mohan, M.1
Jagannathan, N.2
-
134
-
-
84891853396
-
Cutaneous field cancerization: Clinical, histopathological and therapeutic aspects
-
Torezan, L. A., Festa-Neto, C. Cutaneous field cancerization: clinical, histopathological and therapeutic aspects. An. Bras. Dermatol. 88, 775-786 (2013).
-
(2013)
An. Bras. Dermatol.
, vol.88
, pp. 775-786
-
-
Torezan, L.A.1
Festa-Neto, C.2
-
135
-
-
84859227133
-
Field cancerization in Barrett's esophagus
-
Zeki, S. S., McDonald, S. A., Graham, T. A. Field cancerization in Barrett's esophagus. Discov. Med. 12, 371-379 (2011).
-
(2011)
Discov. Med.
, vol.12
, pp. 371-379
-
-
Zeki, S.S.1
McDonald, S.A.2
Graham, T.A.3
-
136
-
-
84870684515
-
Field cancerization in mammary carcinogenesis-implications for prevention and treatment of breast cancer
-
Rivenbark, A. G., Coleman, W. B. Field cancerization in mammary carcinogenesis-implications for prevention and treatment of breast cancer. Exp. Mol. Pathol. 93, 391-398 (2012).
-
(2012)
Exp. Mol. Pathol.
, vol.93
, pp. 391-398
-
-
Rivenbark, A.G.1
Coleman, W.B.2
-
137
-
-
84942930135
-
Signatures of post-zygotic structural genetic aberrations in the cells of histologically normal breast tissue that can predispose to sporadic breast cancer
-
Forsberg, L. A. et al. Signatures of post-zygotic structural genetic aberrations in the cells of histologically normal breast tissue that can predispose to sporadic breast cancer. Genome Res. 25, 1521-1535 (2015).
-
(2015)
Genome Res.
, vol.25
, pp. 1521-1535
-
-
Forsberg, L.A.1
-
138
-
-
84859393237
-
Field cancerization in the intestinal epithelium of patients with Crohn's ileocolitis
-
Galandiuk, S. et al. Field cancerization in the intestinal epithelium of patients with Crohn's ileocolitis. Gastroenterology 142, 855-864.e8 (2012).
-
(2012)
Gastroenterology
, vol.142
, pp. 855-855e8
-
-
Galandiuk, S.1
-
139
-
-
77953774777
-
The origins of urothelial carcinoma
-
Cheng, L. et al. The origins of urothelial carcinoma. Expert Rev. Anticancer Ther. 10, 865-880 (2010).
-
(2010)
Expert Rev. Anticancer Ther.
, vol.10
, pp. 865-880
-
-
Cheng, L.1
-
140
-
-
84905502758
-
Ordering of mutations in preinvasive disease stages of esophageal carcinogenesis
-
Weaver, J. M. et al. Ordering of mutations in preinvasive disease stages of esophageal carcinogenesis. Nat. Genet. 46, 837-843 (2014).
-
(2014)
Nat. Genet.
, vol.46
, pp. 837-843
-
-
Weaver, J.M.1
-
141
-
-
0028085214
-
UV and skin cancer: Specific p53 gene mutation in normal skin as a biologically relevant exposure measurement
-
Nakazawa, H. et al. UV and skin cancer: specific p53 gene mutation in normal skin as a biologically relevant exposure measurement. Proc. Natl Acad. Sci. USA 91, 360-364 (1994).
-
(1994)
Proc. Natl Acad. Sci. USA
, vol.91
, pp. 360-364
-
-
Nakazawa, H.1
-
142
-
-
0028596185
-
Sunburn and p53 in the onset of skin cancer
-
Ziegler, A. et al. Sunburn and p53 in the onset of skin cancer. Nature 372, 773-776 (1994).
-
(1994)
Nature
, vol.372
, pp. 773-776
-
-
Ziegler, A.1
-
143
-
-
70350646899
-
Activating mutations in FGFR3 and HRAS reveal a shared genetic origin for congenital disorders and testicular tumors
-
Goriely, A. et al. Activating mutations in FGFR3 and HRAS reveal a shared genetic origin for congenital disorders and testicular tumors. Nat. Genet. 41, 1247-1252 (2009).
-
(2009)
Nat. Genet.
, vol.41
, pp. 1247-1252
-
-
Goriely, A.1
-
144
-
-
84899077299
-
Cellular evidence for selfish spermatogonial selection in aged human testes
-
Maher, G. J., Goriely, A., Wilkie, A. O. Cellular evidence for selfish spermatogonial selection in aged human testes. Andrology 2, 304-314 (2014).
-
(2014)
Andrology
, vol.2
, pp. 304-314
-
-
Maher, G.J.1
Goriely, A.2
Wilkie, A.O.3
-
145
-
-
84861971342
-
Multifocal epithelial tumors and field cancerization from loss of mesenchymal CSL signaling
-
Hu, B. et al. Multifocal epithelial tumors and field cancerization from loss of mesenchymal CSL signaling. Cell 149, 1207-1220 (2012).
-
(2012)
Cell
, vol.149
, pp. 1207-1220
-
-
Hu, B.1
-
146
-
-
84936890500
-
Subclonal diversification of primary breast cancer revealed by multiregion sequencing
-
Yates, L. R. et al. Subclonal diversification of primary breast cancer revealed by multiregion sequencing. Nat. Med. 21, 751-759 (2015).
-
(2015)
Nat. Med.
, vol.21
, pp. 751-759
-
-
Yates, L.R.1
-
147
-
-
2042437650
-
Initial sequencing and analysis of the human genome
-
Lander, E. S. et al. Initial sequencing and analysis of the human genome. Nature 409, 860-921 (2001).
-
(2001)
Nature
, vol.409
, pp. 860-921
-
-
Lander, E.S.1
-
148
-
-
0037965788
-
Hot L1s account for the bulk of retrotransposition in the human population
-
Brouha, B. et al. Hot L1s account for the bulk of retrotransposition in the human population. Proc. Natl Acad. Sci. USA 100, 5280-5285 (2003).
-
(2003)
Proc. Natl Acad. Sci. USA
, vol.100
, pp. 5280-5285
-
-
Brouha, B.1
-
149
-
-
66149168927
-
L1 retrotransposition occurs mainly in embryogenesis and creates somatic mosaicism
-
Kano, H. et al. L1 retrotransposition occurs mainly in embryogenesis and creates somatic mosaicism. Genes Dev. 23, 1303-1312 (2009).
-
(2009)
Genes Dev.
, vol.23
, pp. 1303-1312
-
-
Kano, H.1
-
150
-
-
84863892710
-
Human aneuploidy: Mechanisms and new insights into an age-old problem
-
Nagaoka, S. I., Hassold, T. J., Hunt, P. A. Human aneuploidy: mechanisms and new insights into an age-old problem. Nat. Rev. Genet. 13, 493-504 (2012).
-
(2012)
Nat. Rev. Genet.
, vol.13
, pp. 493-504
-
-
Nagaoka, S.I.1
Hassold, T.J.2
Hunt, P.A.3
-
151
-
-
33845274890
-
Detection of low-level mosaicism by array CGH in routine diagnostic specimens
-
Ballif, B. C. et al. Detection of low-level mosaicism by array CGH in routine diagnostic specimens. Am. J. Med. Genet. A 140, 2757-2767 (2006).
-
(2006)
Am. J. Med. Genet. A
, vol.140
, pp. 2757-2767
-
-
Ballif, B.C.1
-
152
-
-
40849109768
-
Phenotypically concordant and discordant monozygotic twins display different DNA copy-number-variation profiles
-
Bruder, C. E. et al. Phenotypically concordant and discordant monozygotic twins display different DNA copy-number-variation profiles. Am. J. Hum. Genet. 82, 763-771 (2008).
-
(2008)
Am. J. Hum. Genet.
, vol.82
, pp. 763-771
-
-
Bruder, C.E.1
-
153
-
-
51549095601
-
Somatic mosaicism for copy number variation in differentiated human tissues
-
Piotrowski, A. et al. Somatic mosaicism for copy number variation in differentiated human tissues. Hum. Mutat. 29, 1118-1124 (2008).
-
(2008)
Hum. Mutat.
, vol.29
, pp. 1118-1124
-
-
Piotrowski, A.1
-
154
-
-
81955168032
-
The consequences of structural genomic alterations in humans: Genomic disorders, genomic instability and cancer
-
Colnaghi, R., Carpenter, G., Volker, M., O'Driscoll, M. The consequences of structural genomic alterations in humans: genomic disorders, genomic instability and cancer. Semin. Cell Dev. Biol. 22, 875-885 (2011).
-
(2011)
Semin. Cell Dev. Biol.
, vol.22
, pp. 875-885
-
-
Colnaghi, R.1
Carpenter, G.2
Volker, M.3
O'Driscoll, M.4
-
155
-
-
84862491113
-
Mechanisms for recurrent and complex human genomic rearrangements
-
Liu, P., Carvalho, C. M., Hastings, P. J., Lupski, J. R. Mechanisms for recurrent and complex human genomic rearrangements. Curr. Opin. Genet. Dev. 22, 211-220 (2012).
-
(2012)
Curr. Opin. Genet. Dev.
, vol.22
, pp. 211-220
-
-
Liu, P.1
Carvalho, C.M.2
Hastings, P.J.3
Lupski, J.R.4
-
156
-
-
37349109667
-
A DNA replication mechanism for generating nonrecurrent rearrangements associated with genomic disorders
-
Lee, J. A., Carvalho, C. M., Lupski, J. R. A DNA replication mechanism for generating nonrecurrent rearrangements associated with genomic disorders. Cell 131, 1235-1247 (2007).
-
(2007)
Cell
, vol.131
, pp. 1235-1247
-
-
Lee, J.A.1
Carvalho, C.M.2
Lupski, J.R.3
-
157
-
-
59249105978
-
A microhomology-mediated break-induced replication model for the origin of human copy number variation
-
Hastings, P. J., Ira, G., Lupski, J. R. A microhomology-mediated break-induced replication model for the origin of human copy number variation. PLoS Genet. 5, e1000327 (2009).
-
(2009)
PLoS Genet.
, vol.5
, pp. e1000327
-
-
Hastings, P.J.1
Ira, G.2
Lupski, J.R.3
-
158
-
-
78650959663
-
Massive genomic rearrangement acquired in a single catastrophic event during cancer development
-
Stephens, P. J. et al. Massive genomic rearrangement acquired in a single catastrophic event during cancer development. Cell 144, 27-40 (2011).
-
(2011)
Cell
, vol.144
, pp. 27-40
-
-
Stephens, P.J.1
-
159
-
-
84863393824
-
Chromothripsis and human disease: Piecing together the shattering process
-
Maher, C. A., Wilson, R. K. Chromothripsis and human disease: piecing together the shattering process. Cell 148, 29-32 (2012).
-
(2012)
Cell
, vol.148
, pp. 29-32
-
-
Maher, C.A.1
Wilson, R.K.2
-
160
-
-
62249091705
-
Uniparental disomy in cancer
-
Tuna, M., Knuutila, S., Mills, G. B. Uniparental disomy in cancer. Trends Mol. Med. 15, 120-128 (2009).
-
(2009)
Trends Mol. Med.
, vol.15
, pp. 120-128
-
-
Tuna, M.1
Knuutila, S.2
Mills, G.B.3
-
161
-
-
84928770050
-
Detecting somatic mosaicism: Considerations and clinical implications
-
Cohen, A. S., Wilson, S. L., Trinh, J., Ye, X. C. Detecting somatic mosaicism: considerations and clinical implications. Clin. Genet. 87, 554-562 (2015).
-
(2015)
Clin. Genet.
, vol.87
, pp. 554-562
-
-
Cohen, A.S.1
Wilson, S.L.2
Trinh, J.3
Ye, X.C.4
-
162
-
-
84856822067
-
Realm of revertant mosaicism expanding
-
Jonkman, M. F., Pasmooij, A. M. Realm of revertant mosaicism expanding. J. Invest. Dermatol. 132, 514-516 (2012).
-
(2012)
J. Invest. Dermatol.
, vol.132
, pp. 514-516
-
-
Jonkman, M.F.1
Pasmooij, A.M.2
-
163
-
-
0032923739
-
Generalized lacZ expression with the ROSA26 Cre reporter strain
-
Soriano, P. Generalized lacZ expression with the ROSA26 Cre reporter strain. Nat. Genet. 21, 70-71 (1999).
-
(1999)
Nat. Genet.
, vol.21
, pp. 70-71
-
-
Soriano, P.1
-
164
-
-
84865797462
-
MASTR: A technique for mosaic mutant analysis with spatial and temporal control of recombination using conditional floxed alleles in mice
-
Lao, Z., Raju, G. P., Bai, C. B., Joyner, A. L. MASTR: a technique for mosaic mutant analysis with spatial and temporal control of recombination using conditional floxed alleles in mice. Cell Rep. 2, 386-396 (2012).
-
(2012)
Cell Rep.
, vol.2
, pp. 386-396
-
-
Lao, Z.1
Raju, G.P.2
Bai, C.B.3
Joyner, A.L.4
-
165
-
-
84964314145
-
A next-generation dual-recombinase system for time-and host-specific targeting of pancreatic cancer
-
Schonhuber, N. et al. A next-generation dual-recombinase system for time-and host-specific targeting of pancreatic cancer. Nat. Med. 20, 1340-1347 (2014).
-
(2014)
Nat. Med.
, vol.20
, pp. 1340-1347
-
-
Schonhuber, N.1
-
166
-
-
0041883654
-
Tumor induction by an endogenous K-ras oncogene is highly dependent on cellular context
-
Guerra, C. et al. Tumor induction by an endogenous K-ras oncogene is highly dependent on cellular context. Cancer Cell 4, 111-120 (2003).
-
(2003)
Cancer Cell
, vol.4
, pp. 111-120
-
-
Guerra, C.1
-
167
-
-
33847419143
-
Chronic pancreatitis is essential for induction of pancreatic ductal adenocarcinoma by K-Ras oncogenes in adult mice
-
Guerra, C. et al. Chronic pancreatitis is essential for induction of pancreatic ductal adenocarcinoma by K-Ras oncogenes in adult mice. Cancer Cell 11, 291-302 (2007).
-
(2007)
Cancer Cell
, vol.11
, pp. 291-302
-
-
Guerra, C.1
-
168
-
-
0030843461
-
Rapid colorectal adenoma formation initiated by conditional targeting of the Apc gene
-
Shibata, H. et al. Rapid colorectal adenoma formation initiated by conditional targeting of the Apc gene. Science 278, 120-123 (1997).
-
(1997)
Science
, vol.278
, pp. 120-123
-
-
Shibata, H.1
-
169
-
-
59049106578
-
Crypt stem cells as the cells-of-origin of intestinal cancer
-
Barker, N. et al. Crypt stem cells as the cells-of-origin of intestinal cancer. Nature 457, 608-611 (2009).
-
(2009)
Nature
, vol.457
, pp. 608-611
-
-
Barker, N.1
-
170
-
-
84864854371
-
Lineage tracing reveals Lgr5+ stem cell activity in mouse intestinal adenomas
-
Schepers, A. G. et al. Lineage tracing reveals Lgr5+ stem cell activity in mouse intestinal adenomas. Science 337, 730-735 (2012).
-
(2012)
Science
, vol.337
, pp. 730-735
-
-
Schepers, A.G.1
-
171
-
-
84881477172
-
Myc-driven endogenous cell competition in the early mammalian embryo
-
Claveria, C., Giovinazzo, G., Sierra, R., Torres, M. Myc-driven endogenous cell competition in the early mammalian embryo. Nature 500, 39-44 (2013).
-
(2013)
Nature
, vol.500
, pp. 39-44
-
-
Claveria, C.1
Giovinazzo, G.2
Sierra, R.3
Torres, M.4
-
172
-
-
84907390474
-
Cell competition promotes phenotypically silent cardiomyocyte replacement in the mammalian heart
-
Villa del Campo, C., Claveria, C., Sierra, R., Torres, M. Cell competition promotes phenotypically silent cardiomyocyte replacement in the mammalian heart. Cell Rep. 8, 1741-1751 (2014).
-
(2014)
Cell Rep.
, vol.8
, pp. 1741-1751
-
-
Villa Del Campo, C.1
Claveria, C.2
Sierra, R.3
Torres, M.4
-
173
-
-
0016613341
-
Minutes: Mutants of Drosophila autonomously affecting cell division rate
-
Morata, G., Ripoll, P. Minutes: mutants of Drosophila autonomously affecting cell division rate. Dev. Biol. 42, 211-221 (1975).
-
(1975)
Dev. Biol.
, vol.42
, pp. 211-221
-
-
Morata, G.1
Ripoll, P.2
-
174
-
-
0037129195
-
Cells compete for decapentaplegic survival factor to prevent apoptosis in Drosophila wing development
-
Moreno, E., Basler, K., Morata, G. Cells compete for decapentaplegic survival factor to prevent apoptosis in Drosophila wing development. Nature 416, 755-759 (2002).
-
(2002)
Nature
, vol.416
, pp. 755-759
-
-
Moreno, E.1
Basler, K.2
Morata, G.3
-
175
-
-
84894086619
-
Cell competition: How to eliminate your neighbours
-
Amoyel, M., Bach, E. A. Cell competition: how to eliminate your neighbours. Development 141, 988-1000 (2014).
-
(2014)
Development
, vol.141
, pp. 988-1000
-
-
Amoyel, M.1
Bach, E.A.2
-
176
-
-
84901839347
-
Functions of the Drosophila JAK-STAT pathway: Lessons from stem cells
-
Amoyel, M., Bach, E. A. Functions of the Drosophila JAK-STAT pathway: lessons from stem cells. JAKSTAT 1, 176-183 (2012).
-
(2012)
JAKSTAT
, vol.1
, pp. 176-183
-
-
Amoyel, M.1
Bach, E.A.2
-
177
-
-
38549147654
-
Is cell competition relevant to cancer
-
Moreno, E. Is cell competition relevant to cancer Nat. Rev. Cancer 8, 141-147 (2008).
-
(2008)
Nat. Rev. Cancer
, vol.8
, pp. 141-147
-
-
Moreno, E.1
-
178
-
-
64049115862
-
Characterization of the interface between normal and transformed epithelial cells
-
Hogan, C. et al. Characterization of the interface between normal and transformed epithelial cells. Nat. Cell Biol. 11, 460-467 (2009).
-
(2009)
Nat. Cell Biol.
, vol.11
, pp. 460-467
-
-
Hogan, C.1
-
179
-
-
77955971943
-
A tumor-suppressing mechanism in Drosophila involving cell competition and the Hippo pathway
-
Menendez, J., Perez-Garijo, A., Calleja, M., Morata, G. A tumor-suppressing mechanism in Drosophila involving cell competition and the Hippo pathway. Proc. Natl Acad. Sci. USA 107, 14651-14656 (2010).
-
(2010)
Proc. Natl Acad. Sci. USA
, vol.107
, pp. 14651-14656
-
-
Menendez, J.1
Perez-Garijo, A.2
Calleja, M.3
Morata, G.4
-
180
-
-
85028194578
-
Cell competition may function either as tumour-suppressing or as tumour-stimulating factor in Drosophila
-
Ballesteros-Arias, L., Saavedra, V., Morata, G. Cell competition may function either as tumour-suppressing or as tumour-stimulating factor in Drosophila. Oncogene 33, 4377-4384 (2013).
-
(2013)
Oncogene
, vol.33
, pp. 4377-4384
-
-
Ballesteros-Arias, L.1
Saavedra, V.2
Morata, G.3
-
181
-
-
75749106942
-
Interaction between RasV12 and scribbled clones induces tumour growth and invasion
-
Wu, M., Pastor-Pareja, J. C., Xu, T. Interaction between RasV12 and scribbled clones induces tumour growth and invasion. Nature 463, 545-548 (2010).
-
(2010)
Nature
, vol.463
, pp. 545-548
-
-
Wu, M.1
Pastor-Pareja, J.C.2
Xu, T.3
-
182
-
-
42049095950
-
Distinct mechanisms of apoptosis-induced compensatory proliferation in proliferating and differentiating tissues in the Drosophila eye
-
Fan, Y., Bergmann, A. Distinct mechanisms of apoptosis-induced compensatory proliferation in proliferating and differentiating tissues in the Drosophila eye. Dev. Cell 14, 399-410 (2008).
-
(2008)
Dev. Cell
, vol.14
, pp. 399-410
-
-
Fan, Y.1
Bergmann, A.2
-
183
-
-
29144453339
-
Dpp signaling and the induction of neoplastic tumors by caspase-inhibited apoptotic cells in Drosophila
-
Perez-Garijo, A., Martin, F. A., Struhl, G., Morata, G. Dpp signaling and the induction of neoplastic tumors by caspase-inhibited apoptotic cells in Drosophila. Proc. Natl Acad. Sci. USA 102, 17664-17669 (2005).
-
(2005)
Proc. Natl Acad. Sci. USA
, vol.102
, pp. 17664-17669
-
-
Perez-Garijo, A.1
Martin, F.A.2
Struhl, G.3
Morata, G.4
-
184
-
-
33845478597
-
Regulation of imaginal disc growth by tumor-suppressor genes in Drosophila
-
Hariharan, I. K., Bilder, D. Regulation of imaginal disc growth by tumor-suppressor genes in Drosophila. Annu. Rev. Genet. 40, 335-361 (2006).
-
(2006)
Annu. Rev. Genet.
, vol.40
, pp. 335-361
-
-
Hariharan, I.K.1
Bilder, D.2
-
185
-
-
83455176258
-
Mosaic amplification of multiple receptor tyrosine kinase genes in glioblastoma
-
Snuderl, M. et al. Mosaic amplification of multiple receptor tyrosine kinase genes in glioblastoma. Cancer Cell 20, 810-817 (2011).
-
(2011)
Cancer Cell
, vol.20
, pp. 810-817
-
-
Snuderl, M.1
-
186
-
-
84857397985
-
Intratumoral heterogeneity of receptor tyrosine kinases EGFR and PDGFRA amplification in glioblastoma defines subpopulations with distinct growth factor response
-
Szerlip, N. J. et al. Intratumoral heterogeneity of receptor tyrosine kinases EGFR and PDGFRA amplification in glioblastoma defines subpopulations with distinct growth factor response. Proc. Natl Acad. Sci. USA 109, 3041-3046 (2012).
-
(2012)
Proc. Natl Acad. Sci. USA
, vol.109
, pp. 3041-3046
-
-
Szerlip, N.J.1
-
187
-
-
84933279834
-
Lymphatic and other vascular malformative/overgrowth disorders are caused by somatic mutations in PIK3CA
-
Luks, V. L. et al. Lymphatic and other vascular malformative/overgrowth disorders are caused by somatic mutations in PIK3CA. J. Pediatr. 166, 1048-1054 (2015).
-
(2015)
J. Pediatr.
, vol.166
, pp. 1048-1054
-
-
Luks, V.L.1
-
188
-
-
84907177667
-
Mosaic partial deletion of the PTEN gene in a patient with Cowden syndrome
-
Salo-Mullen, E. E. et al. Mosaic partial deletion of the PTEN gene in a patient with Cowden syndrome. Fam. Cancer 13, 459-467 (2014).
-
(2014)
Fam. Cancer
, vol.13
, pp. 459-467
-
-
Salo-Mullen, E.E.1
-
189
-
-
84867096540
-
PGD for germline mosaicism
-
Altarescu, G. et al. PGD for germline mosaicism. Reprod. Biomed. Online 25, 390-395 (2012).
-
(2012)
Reprod. Biomed. Online
, vol.25
, pp. 390-395
-
-
Altarescu, G.1
-
190
-
-
84879995215
-
Diagnostic value of investigating GNAS mutations in fibro-osseous lesions: A retrospective study of 91 cases of fibrous dysplasia and 40 other fibro-osseous lesions
-
Tabareau-Delalande, F. et al. Diagnostic value of investigating GNAS mutations in fibro-osseous lesions: a retrospective study of 91 cases of fibrous dysplasia and 40 other fibro-osseous lesions. Mod. Pathol. 26, 911-921 (2013).
-
(2013)
Mod. Pathol.
, vol.26
, pp. 911-921
-
-
Tabareau-Delalande, F.1
-
191
-
-
67650403821
-
Genotype-phenotype correlations in Fanconi anemia
-
Neveling, K., Endt, D., Hoehn, H., Schindler, D. Genotype-phenotype correlations in Fanconi anemia. Mutat. Res. 668, 73-91 (2009).
-
(2009)
Mutat. Res.
, vol.668
, pp. 73-91
-
-
Neveling, K.1
Endt, D.2
Hoehn, H.3
Schindler, D.4
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